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Topic:Equine Health

Equine health encompasses the study and management of diseases, disorders, and overall well-being of horses. It involves understanding various physiological systems, preventive care, and treatment strategies to maintain optimal health in equine populations. Common areas of focus include nutrition, infectious diseases, orthopedic conditions, and reproductive health. Research in equine health aims to advance knowledge on diagnostic methods, therapeutic interventions, and management practices that improve horse welfare and performance. This page collects peer-reviewed research studies and scholarly articles that explore the diverse aspects of equine health, offering insights into current findings and advancements in the field.
Posttranscriptional effector domains in the Rev proteins of feline immunodeficiency virus and equine infectious anemia virus.
Journal of virology    March 1, 1994   Volume 68, Issue 3 1998-2001 doi: 10.1128/JVI.68.3.1998-2001.1994
Mancuso VA, Hope TJ, Zhu L, Derse D, Phillips T, Parslow TG.By systematically dissecting the Rev proteins of feline immunodeficiency virus (FIV) and equine infectious anemia virus (EIAV), we have identified within each a short peptide that is functionally interchangeable with the effector domains found in Rev-like proteins from other retroviruses. The active sequences from FIV and EIAV differ in several respects from other known effectors and may represent a distinct class of effector domain.
Welfare of competition horses.
Revue scientifique et technique (International Office of Epizootics)    March 1, 1994   Volume 13, Issue 1 217-232 doi: 10.20506/rst.13.1.765
Atock MA, Williams RB.In the large majority of cases and circumstances, horses benefit from their association with man. However, abuse of horses can occur, due to neglect or through the pressures of competition. The welfare of all animals, including competition horses, has become increasingly topical over the past ten years. Equestrian sport is coming under closer public scrutiny due to reports of apparent abuse. The bodies responsible for regulating these sports strenuously endeavour to protect the welfare of horses which compete under their rules and regulations. The Fédération Equestre Internationale (FEI: Int...
Coccidioides immitis abortion in an Arabian mare.
Veterinary pathology    March 1, 1994   Volume 31, Issue 2 258-259 doi: 10.1177/030098589403100217
Stoltz JH, Johnson BJ, Walker RL, Pappagianis D.No abstract available
Effect of xylazine and ketamine on the pharmacokinetics of alfentanil during halothane anaesthesia.
British journal of anaesthesia    March 1, 1994   Volume 72, Issue 3 345-347 doi: 10.1093/bja/72.3.345
Pascoe PJ, Black WD, Steffey EP.We measured plasma concentrations of alfentanil in two horses after three different randomly ordered treatments. Each horse received halothane in oxygen by mask followed by a bolus dose of alfentanil 60 micrograms kg-1 i.v., halothane in oxygen by mask followed by an i.v. alfentanil infusion for 120 min and xylazine and ketamine followed by halothane and a bolus dose of alfentanil 60 micrograms kg-1 i.v. Halothane was maintained at 1.05-1.07% end-tidal concentration with a PaCO2 of 6-7.3 kPa. The plasma concentration-time curves were similar after bolus and infusion doses of alfentanil with ha...
Skeletal muscle mitochondrial myopathy as a cause of exercise intolerance in a horse.
Muscle & nerve    March 1, 1994   Volume 17, Issue 3 305-312 doi: 10.1002/mus.880170308
Valberg SJ, Carlson GP, Cardinet GH, Birks EK, Jones JH, Chomyn A, DiMauro S.Although exertional myopathies are commonly recognized in horses, specific etiologies have not been identified. This is the first report in the horse of a deficiency of Complex I respiratory chain enzyme associated with profound exercise intolerance. Physical examination, routine blood tests, endoscopy, and ultrasonograms of the heart and iliac arteries were unremarkable. With slow, incremental exercise (speeds 1.5-7 m/s), the Arabian mare showed a marked lactic acidosis, increased mixed venous PVO2, and little change in oxygen consumption. Muscle biopsies contained large accumulations of mito...
The role of the carotid chemoreceptors in the control of breathing during exercise.
Medicine and science in sports and exercise    March 1, 1994   Volume 26, Issue 3 328-336 
Forster HV, Pan LG.Our objective was to gain insight into the role of the carotid chemoreceptors (CC) in the exercise hyperpnea. Humans and ponies were studied at rest and during submaximal exercise breathing room air. In healthy humans, alveolar ventilation (VA) was tightly matched to CO2 production (CO2) resulting in PaCO2 deviating during exercise less than 1-2 mm Hg from rest. In contrast, ponies' VA increased proportionately more than VCO2 during exercise resulting in a workload dependent hypocapnia. Attenuating CC activity through hyperoxia had no effect on exercise PaCO2 of humans but hyperoxia accentuate...
Caprylic acid fractionation of hyperimmune horse plasma: description of a simple procedure for antivenom production.
Toxicon : official journal of the International Society on Toxinology    March 1, 1994   Volume 32, Issue 3 351-363 doi: 10.1016/0041-0101(94)90087-6
Rojas G, Jiménez JM, Gutiérrez JM.A simple methodology for hyperimmune horse plasma fractionation, based on caprylic acid precipitation, is described. Optimal conditions for fractionation were studied; the method gives best results when concentrated caprylic acid was added to plasma, whose pH had been adjusted to 5.8, until a final caprylic acid concentration of 5% was reached. The mixture was vigorously stirred during caprylic acid addition and then for 60 min; afterwards the mixture was filtered. Non-immunoglobulin proteins precipitated in these conditions, whereas a highly enriched immunoglobulin preparation was obtained in...
Tetanus in the horse: a review of 20 cases (1970 to 1990).
Journal of veterinary internal medicine    March 1, 1994   Volume 8, Issue 2 128-132 doi: 10.1111/j.1939-1676.1994.tb03210.x
Green SL, Little CB, Baird JD, Tremblay RR, Smith-Maxie LL.The case records of 20 horses with tetanus referred to the Ontario Veterinary College-Veterinary Teaching Hospital between 1970 and 1990 were reviewed. The fatality rate was 75%. There was a strong association with previous vaccination and survival (P = .03). Most of the animals had been injured an average of 9 days (range 2 to 21 days) prior to development of clinical signs. Hyperesthesia and prolapse of the third eyelid were the most common clinical signs. Treatment regimens varied during hospitalization; however, all horses received parenteral penicillin, tranquilizers, tetanus toxoid, and ...
Diaphragm and lung afferents contribute to inspiratory load compensation in awake ponies.
Journal of applied physiology (Bethesda, Md. : 1985)    March 1, 1994   Volume 76, Issue 3 1330-1339 doi: 10.1152/jappl.1994.76.3.1330
Forster HV, Lowry TF, Pan LG, Erickson BK, Korducki MJ, Forster MA.We determined the effect of pulmonary vagal (hilar nerve) denervation (HND) and diaphragm deafferentation (DD) on inspiratory load compensation. We studied awake intact (I; n = 10), DD (n = 5), HND (n = 4), and DD+HND (n = 7) ponies at rest and during mild (1.8 mph, 5% grade) and moderate (1.8 mph, 15% grade) treadmill exercise before, during, and after resistance of the inspiratory circuit was increased from approximately 1.5 to approximately 20 cmH2O.l-1.s. During the first loaded breath in I ponies at rest, inspiratory time (TI) increased, expiratory time decreased, and inspiratory drive in...
Effects of acetylpromazine, xylazine, and vertical load on digital arterial blood flow in horses.
American journal of veterinary research    March 1, 1994   Volume 55, Issue 3 375-378 
Hunt RJ, Brandon CI, McCann ME.Palmar digital arterial blood flow was measured in 6 conscious, standing horses, using surgically placed perivascular ultrasonic flow probes. The effects of 2 dosages of xylazine (0.55 and 1.1 mg/kg of body weight) and of 3 dosages of acetylpromazine (0.01, 0.02, and 0.04 mg/kg), as well as the effect of vertical load, on digital blood flow were evaluated. Intravenous administration of xylazine induced a significant (P < 0.05), transient decrease in digital blood flow. Intravenous administration of acetylpromazine induced a significant (P < 0.05), prolonged increase in digital blood flow...
Progression and association with lameness and racing performance of radiographic changes in the proximal sesamoid bones of young standardbred trotters.
Equine veterinary journal    March 1, 1994   Volume 26, Issue 2 152-155 doi: 10.1111/j.2042-3306.1994.tb04356.x
Grøndahl AM, Gaustad G, Engeland A.Radiographic examination of the metacarpo- and metatarsophalangeal joints was performed on 753 Standardbred trotters (6-21 months of age): 21 showed obvious changes in 26 proximal sesamoid bones on lateromedial projection. The radiographic changes were divided into 6 different types: (1) irregular abaxial margin (8 horses); (2) enlargement of the sesamoid bone (6 horses); (3) 'fracture' or separate centre of ossification of the apex (4 horses); (4) vertical, non-articular fracture of the plantar part of the sesamoid bone (1 horse); (5) a small bony fragment located in a defect in the apical pa...
Recommendations for the control of anthelmintic resistant nematodes of farm animals in the EU.
The Veterinary record    February 26, 1994   Volume 134, Issue 9 205-206 doi: 10.1136/vr.134.9.205
Coles GC, Borgsteede FH, Geerts S.As a result of a recent European Union meeting on anthelmintic resistant nematodes of farm animals, a list was made of nine proposals for research and five to control anthelmintic resistance. The most important were the need to have standardised and new tests to monitor the development and spread of resistant nematodes in sheep, goats, horses, cattle and pigs, and for education of veterinary surgeons and farmers in the optimal control strategies to be used to delay the development of anthelmintic resistance in nematodes.
Pregnancy diagnosis by ultrasound.
The Veterinary record    February 26, 1994   Volume 134, Issue 9 223 doi: 10.1136/vr.134.9.223-a
Gabriel DC, Webster J.No abstract available
Horses and MRLs.
The Veterinary record    February 26, 1994   Volume 134, Issue 9 224 doi: 10.1136/vr.134.9.224-a
Cole MJ.No abstract available
Pyrexia associated with respiratory disease in young thoroughbred horses.
The Veterinary record    February 26, 1994   Volume 134, Issue 9 219-220 doi: 10.1136/vr.134.9.219
Burrell MH, Whitwell KE, Wood JL, Mumford JA.No abstract available
Epidemiological observations on sarcoids in a population of donkeys (Equus asinus).
The Veterinary record    February 26, 1994   Volume 134, Issue 9 207-211 doi: 10.1136/vr.134.9.207
Reid SW, Gettinby G, Fowler JN, Ikin P.An epidemiological study of equine sarcoid in a population of 4126 donkeys showed that the peak incidence of the disease was 15.2 cases per 100 animal-years and occurred in animals in their fourth year of life. The crude incidence of the disease was 0.6 cases per 100 animal-years. The disease occurred most frequently in younger, male animals during their first five years in the population. The lesions were observed most commonly in the paragenital region. Pre-entry quarantine procedures did not appear to play a significant role in the spread of the disease but there was an indication that clos...
Gastrojejunostomy for management of acute proximal enteritis in a horse.
Journal of the American Veterinary Medical Association    February 15, 1994   Volume 204, Issue 4 633-635 
Gillis JP, Taylor TS, Puckett MJ.A 5-year-old Arabian stallion was treated medically 6 days for proximal enteritis. On the sixth day, exploratory celiotomy verified the diagnosis and ruled out other intraluminal and extraluminal gastrointestinal tract obstructions. A gastrojejunostomy was performed. The horse had trouble maintaining and gaining weight in the first year after surgery, but 8 years after surgery, the owner reported that the horse was doing well.
Molecular entrapment of small molecules within the interior of horse spleen ferritin.
Archives of biochemistry and biophysics    February 15, 1994   Volume 309, Issue 1 178-183 doi: 10.1006/abbi.1994.1100
Webb B, Frame J, Zhao Z, Lee ML, Watt GD.A procedure for trapping small molecules inside the interior of horse spleen ferritin (HoSF) and methods for characterizing HoSF and its small entrapped molecules are described. HoSF is first dissociated into subunits by adjustment to pH 2 in the presence of the small molecules to be trapped. The pH of the dissociated HoSF is then increased to 7 at which time the dissociated subunits reassemble reforming the 24-mer HoSF, thereby trapping solvent within its interior. HoSF is then separated from unbound molecules by dialysis, ultrafiltration, and/or ammonium sulfate precipitation. Sephadex G-25 ...
Diagnostic testing for pituitary pars intermedia dysfunction in horses.
Journal of the American Veterinary Medical Association    February 15, 1994   Volume 204, Issue 4 627-632 
Dybdal NO, Hargreaves KM, Madigan JE, Gribble DH, Kennedy PC, Stabenfeldt GH.Pituitary pars intermedia dysfunction is a slowly progressive disorder that afflicts most breeds of horses. Because it shares features with human Cushing disease, it has been referred to as equine Cushing disease. A variety of tests of pituitary-adrenocortical function were performed on horses with evidence of pituitary pars intermediate dysfunction, and results were compared with those in healthy control horses. Diurnal variations in plasma cortisol concentration were not statistically different between control horses and those with pituitary pars intermedia dysfunction. An ACTH stimulation (...
Enhancement of EIAV replication and disease by immunization with a baculovirus-expressed recombinant envelope surface glycoprotein.
Virology    February 15, 1994   Volume 199, Issue 1 247-251 doi: 10.1006/viro.1994.1120
Wang SZ, Rushlow KE, Issel CJ, Cook RF, Cook SJ, Raabe ML, Chong YH, Costa L, Montelaro RC.The potential for antibody-dependent enhancement of replication of macrophage/monocyte tropic viruses has posed a significant problem in the development of vaccines for several animal and human viruses and has raised significant concern in the design of potential AIDS vaccines. Using the previously described equine infectious anemia virus/Shetland pony system as a model for HIV-1 vaccine development, we have evaluated the efficacy of a recombinant subunit vaccine containing a baculovirus-expressed envelope surface glycoprotein (gp90) of EIAV. The results of these trials demonstrate not only th...
Prevalence of, and factors associated with, musculoskeletal racing injuries of thoroughbreds.
Journal of the American Veterinary Medical Association    February 15, 1994   Volume 204, Issue 4 620-626 
Peloso JG, Mundy GD, Cohen ND.All horses diagnosed by a commission veterinarian of the Kentucky Racing Commission as having sustained a musculoskeletal injury, defined as an obvious change in soundness immediately before, during, or after a race held between Jan 1, 1992 and May 31, 1993 were included in a study to determine the prevalence of and factors associated with racing injuries involving the musculoskeletal system of horses competing at 4 Thoroughbred racetracks in Kentucky. During the 17-month study, there were 35,484 racing starts among 7,649 horses in 3,824 official Kentucky Racing Commission races. During this p...
Duration of protective efficacy of equine influenza immunostimulating complex/tetanus vaccines.
The Veterinary record    February 12, 1994   Volume 134, Issue 7 158-162 doi: 10.1136/vr.134.7.158
Mumford JA, Jessett DM, Rollinson EA, Hannant D, Draper ME.Seven previously untreated five-month-old New Forest ponies received two doses of equine influenza immunostimulating complex vaccines, one with and one without an immunopurified tetanus toxoid component, given by deep intramuscular injection six weeks apart, followed by a booster dose without tetanus toxoid five months later. Fifteen months after the third dose of vaccine, the ponies were challenged by exposure to an aerosol of influenza A/Equine 2/Sussex/89 (H3N8), a virus isolated from a recent outbreak of influenza A/equine 2 in Britain. The challenge produced severe clinical signs of influ...
Pregnancy diagnosis by ultrasound.
The Veterinary record    February 12, 1994   Volume 134, Issue 7 176 doi: 10.1136/vr.134.7.176-a
Lloyd CH.No abstract available
Pregnancy diagnosis by ultrasound.
The Veterinary record    February 12, 1994   Volume 134, Issue 7 176 doi: 10.1136/vr.134.7.176
Wain EB, Gillespie ID, Keith NW, McKerchar HB, Anderson R, Taylor D, Lyons C, Johnston CJ.No abstract available
Sperm-induced leukocytosis in the equine uterus.
Theriogenology    February 2, 1994   Volume 41, Issue 3 629-636 doi: 10.1016/0093-691x(94)90173-g
Kotilainen T, Huhtinen M, Katila T.The objective of this study was to investigate the inflammatory reaction induced in the equine uterus by insemination with fresh and frozen semen. Eleven groups (6 to 8 mares per group) were studied during 2 breeding seasons. The mares were inseminated using raw semen, frozen semen, extended fresh and frozen semen, concentrated fresh semen, seminal plasma and seminal extenders only. One group was bred naturally. Six hours after insemination, the uteri were flushed with 50 ml of phosphate-buffered saline (PBS). Seventeen out of 104 samples (16%) exhibited slight bacterial growth. Neutrophil con...
Follicular and FSH responses to parturition during the anovulatory season in mares.
Theriogenology    February 2, 1994   Volume 41, Issue 3 613-627 doi: 10.1016/0093-691x(94)90172-f
Ginther OJ, Baucus KL, Bergfelt DR.The ovaries of periparturient pony mares (n=9 to 16 parturitions per month for January to April) were scanned ultrasonically on the day of parturition, while those of postpartum and control mares (n=12) were examined at least twice weekly. Four mares had apparent lactational anovulation (incidence, 7%) that corrected spontaneously (1 mare) or within 14 d after the weaning of foals on August 10 (3 mares). All but 2 of the postpartum ovulations occurred after April 29; that is, parturition did not effectively stimulate ovulation in ponies foaling during the anovulatory season. Mean diameter of t...
Concentration of ceftiofur metabolites in the plasma and lungs of horses following intramuscular treatment.
Journal of veterinary pharmacology and therapeutics    February 1, 1994   Volume 17, Issue 1 24-30 doi: 10.1111/j.1365-2885.1994.tb00517.x
Jaglan PS, Roof RD, Yein FS, Arnold TS, Brown SA, Gilbertson TJ.Ceftiofur sodium, a broad spectrum cephalosporin antibiotic approved for veterinary use, is metabolized to desfuroylceftiofur which is conjugated to micro as well as macromolecules. Twelve horses, weighting 442-618 kg, were injected intramuscularly with a single dose of 2.2 mg ceftiofur/kg (1.0 mg/lb) body weight. Blood was collected at various intervals over 24 h after treatment. Three groups of four horses each were euthanized and lungs were collected at 1, 12, and 24 h after treatment. The concentration of desfuroylceftiofur and desfuroylceftiofur conjugates in the plasma and lungs was dete...
Scintigraphic and ultrasonographic diagnosis of soft tissue injury in a thoroughbred horse.
The Journal of veterinary medical science    February 1, 1994   Volume 56, Issue 1 169-172 doi: 10.1292/jvms.56.169
Williams J, Miyabayashi T, Ruggles A, Yamamoto J, Takiguchi M.A 2.5-year-old female Thoroughbred horse was referred to the veterinary teaching hospital for right front limb lameness of 1 year duration. Physical examination and diagnostic nerve blocks failed to localize the origin of the lameness. Scintigraphy with 99mTc-MDP suggested increased radionuclide uptake in the palmar metacarpal soft tissues of the right front limb. Ultrasonographic examination revealed hypoechoic lesions in the superficial digital flexor tendon and the suspensory ligament, suggesting tendinitis and desmitis. Combined imaging modalities improved detection and characterization of...
Application to cows and horses of Spotchem, a dry-chemistry blood analyzer for use in veterinary clinics.
Zentralblatt fur Veterinarmedizin. Reihe A    February 1, 1994   Volume 41, Issue 1 22-30 doi: 10.1111/j.1439-0442.1994.tb00061.x
Hoshi F, Satho M, Koyama S, Nakadaka K, Chiba M, Ikeda N, Hakamada R, Higuchi S, Kawamura S.The usefulness of a dry-chemistry blood analyzer, Spotchem SP-4410 (SP-4410) in a veterinary clinic for analysis of bovine and equine blood chemistry was studied. We quantitated total protein (TP), albumin (Alb), total bilirubin (T-Bil), blood urea nitrogen (BUN), total cholesterol (T-Cho), glucose (Glu), calcium (Ca), aspartate aminotransferase (AST), gamma-glutamyltransferase (GGT), creatinine phosphokinase (CPK), and alkaline phosphatase (ALP) in bovine sera. Each sample was assayed with both the SP-4410 and an automated blood analyzer which served as a wet-chemistry reference system, and t...
Comparison of methods of cardiac output measurements determined by dye dilution, pulsed Doppler echocardiography and thermodilution in horses.
The Journal of veterinary medical science    February 1, 1994   Volume 56, Issue 1 1-5 doi: 10.1292/jvms.56.1
Mizuno Y, Aida H, Hara H, Fujinaga T, Hagio M.Cardiac output (CO) measurements by the three methods of dye dilution, pulsed Doppler echocardiography and thermodilution in horses under anesthetized conditions were compared. Although CO determined by the thermodilution method was slightly higher than those obtained by the other two methods, the measurements by all methods showed almost similar results. The coefficients of correlation between the dye dilution and thermodilution methods, the dye dilution and pulsed Doppler echocardiography methods, and the thermodilution and pulsed Doppler echocardiography methods were 0.87, 0.89, and 0.88, r...