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Topic:Equine Health

Equine health encompasses the study and management of diseases, disorders, and overall well-being of horses. It involves understanding various physiological systems, preventive care, and treatment strategies to maintain optimal health in equine populations. Common areas of focus include nutrition, infectious diseases, orthopedic conditions, and reproductive health. Research in equine health aims to advance knowledge on diagnostic methods, therapeutic interventions, and management practices that improve horse welfare and performance. This page collects peer-reviewed research studies and scholarly articles that explore the diverse aspects of equine health, offering insights into current findings and advancements in the field.
Effect of interleukin 1 on articular cartilage from young and aged horses and comparison with metabolism of osteoarthritic cartilage.
American journal of veterinary research    January 1, 1994   Volume 55, Issue 1 138-146 
Morris EA, Treadwell BV.The effect of interleukin 1 (IL-1) on equine articular cartilage was investigated, using a cartilage explant culture system. Measurement of [35S]O4 incorporation revealed synthesis of matrix proteoglycan by cartilage to be decreased 45, 59.7, and 37.5% after 1, 3, and 5 days, respectively, in culture in the presence of 5 U of IL-1/ml. There was no change in proteoglycan degradation as determined by measurement of [35S]O4 release into the culture medium. Sodium dodecyl sulfate-polyacrylamide gel electrophoresis of cartilage-conditioned medium indicated that exposure of cartilage to IL-1 caused ...
Influence of air movement, facemask design and exercise on upper airway, transpulmonary, and transdiaphragmatic pressures in thoroughbred horses.
The Cornell veterinarian    January 1, 1994   Volume 84, Issue 1 77-90 
Bayly WM, Slocombe RF, Weidner JP, Schott HC, Hodgson DR.The influences of facial airflow, exercise and wearing a facemask on gas exchange and upper airway (Pu), transpulmonary (PTP) and transdiaphragmatic (PTD) pressures were investigated in 6 horses performing an incremental exercise test on an inclined (10%) treadmill. The test consisted of a 2 min walk followed by two 2 min exercise bouts at intensities which produced 40% and 80% of maximal oxygen consumption. Horses performed the test 4 times, once for each of 4 protocols, which involved not wearing a facemask (A), wearing a mask with either no biased flow through it (B), with an expiratory bia...
Characterization of horse (Equus caballus) T-cell receptor beta chain genes.
Immunogenetics    January 1, 1994   Volume 40, Issue 2 135-144 doi: 10.1007/BF00188177
Schrenzel MD, Watson JL, Ferrick DA.Genes encoding the horse (Equus caballus) T-cell receptor beta chain (TCRB) were cloned and characterized. Of 33 cDNA clones isolated from the mesenteric lymph node, 30 had functionally rearranged gene segments, and three contained germline sequences. Sixteen unique variable segments (TCRBV), 14 joining genes (TCRBJ), and two constant region genes (TCRBC) were identified. Horse TCRBV were grouped into nine families based on similarity to human sequences. TCRBV2 and TCRBV12 were the most commonly represented horse families. Analysis of predicted protein structure revealed the presence of conser...
Fine structure of equine oocytes matured in vitro for 15 hours.
Molecular reproduction and development    January 1, 1994   Volume 37, Issue 1 87-92 doi: 10.1002/mrd.1080370112
Willis P, Caudle AB, Fayrer-Hosken RA.Transmission electron microscopy (TEM) was used to evaluate the fine structure of equine oocytes cultured in vitro. Oocytes obtained by follicular aspiration were cultured for either zero or 15 hr. After treatment oocytes were processed either by light microscopy (nuclear evaluation) or TEM (cytoplasmic evaluation). Those oocytes cultured for 15 hr were incubated in modified TCM 199 with 15% (v/v) mare serum (day of ovulation) at 39 +/- 0.2 degree C. Evaluation using TEM revealed that cortical granules were present in all oocytes. However, zero-time oocytes contained few cortical granules, and...
Efficacy of intravenous plasma to transfer passive immunity in clinically healthy and clinically ill equine neonates with failure of passive transfer.
The Cornell veterinarian    January 1, 1994   Volume 84, Issue 1 7-14 
Wilkins PA, Dewan-Mix S.The efficacy intravenous plasma to transfer passive immunity to clinically healthy colostrum-deprived and clinically ill foals with failure of passive transfer was investigated. Efficacy of transfer was evaluated by the elevation of serum IgG per gram of IgG administered as a function of body weight. Colostrum deprived healthy foals had a significantly greater increase in serum IgG than did clinically ill foals with failure of passive transfer. Knowledge of the IgG content of plasma to be administered and the health status of a foal with failure of passive transfer should allow more accurate p...
[Hematological reference values for foals in the first two months of life].
Schweizer Archiv fur Tierheilkunde    January 1, 1994   Volume 136, Issue 4 127-136 
Waelchli RO, Lutz H, Hermann M, Rüegg C, Eggenberger E.Hematologic reference values were established in 18 healthy foals in the first two months of life. Blood samples were collected prior to colostrum consumption and at 30 hours, 1 week, 3, 5, 7 and 9 weeks of age. PCV, Hb and RBC decreased during the first week and RBC, but not PCV and Hb, increased toward the end of the second month. With the exception of the sample at 1 week, the foals had mean RBC values significantly higher than those of controls. Mean MCV and MCH did not change during the first week, but decreased slightly thereafter; all means were smaller than in controls. The numbers of ...
Rare alleles, MHC and captive breeding.
EXS    January 1, 1994   Volume 68 187-204 doi: 10.1007/978-3-0348-8510-2_16
Hedrick PW, Miller PS.In recent years, more detailed genetic information has become available for individuals of endangered species in captive breeding programs. There have been suggestions that this information be used to identify rare alleles, particularly those at the MHC, that can be subsequently selected for captive breeding programs. First, we summarize the current information on the MHC relevant to conservation genetics, so that such a possible breeding program is seen in a proper perspective. For example, very few specific alleles at the MHC have been identified as selectively advantageous, even though ther...
Fibre type distribution, capillarization and enzymatic profile of locomotor and nonlocomotor muscles of horses and steers.
Acta anatomica    January 1, 1994   Volume 151, Issue 2 97-106 doi: 10.1159/000147649
Karlström K, Essén-Gustavsson B, Lindholm A.Samples were taken at slaughter from heart and both locomotor and nonlocomotor muscles from animals of similar body weight but adapted to different levels of activity: three horses and three steers. All samples were analyzed biochemically to measure the activity of key metabolic enzymes. The skeletal muscles were analyzed histochemically for fibre type composition, fibre area and capillary supply. The general pattern of differences in fibre type composition and metabolic profile between muscle groups was similar in both horses and steers. The hearts of both species had high citrate synthase (C...
Culture of equine embryos in media containing egg yolk, mare’s milk and saline: Preliminary results.
Theriogenology    January 1, 1994   Volume 41, Issue 6 1201-1206 doi: 10.1016/0093-691x(94)90476-y
Lebedev SG, Lebedeva LF.A medium containing egg yolk, mare's milk and/or modified PBS was used to culture Day-8 to 8.5 equine blastocysts. Twenty-one variants of the medium containing different concentrations of the 3 components were prepared. Embryos were recovered nonsurgically and placed into the media at 37 degrees C for 24 h. A total of 45 embryos was cultured; of these 7 died in culture and 13 showed inadequate development at the onset, while 25 continued to grow in the media. It was established that embryos grew best in media containing 20 to 60% yolk, 20 to 60% mare's milk and/or 20 to 60% PBS. It was found e...
Heparin: a review of its pharmacology and therapeutic use in horses.
Journal of veterinary internal medicine    January 1, 1994   Volume 8, Issue 1 26-35 doi: 10.1111/j.1939-1676.1994.tb03192.x
Moore BR, Hinchcliff KW.Heparin is used clinically in horses to treat hemostatic abnormalities associated with severe gastrointestinal disease, septicemia, and endotoxemia. The primary anticoagulant effect of heparin is through the suppression of thrombin-dependent amplification of the coagulation cascade, and inhibition of thrombin-mediated conversion of fibrinogen to fibrin. Heparin may be of benefit in preventing the complications associated with hypercoagulable states such as jugular vein thrombosis, laminitis, and organ failure. Heparin may also be beneficial in the prevention of intraabdominal adhesions after g...
Diagnosis of eastern equine encephalomyelitis virus infection in horses by immunoglobulin M and G capture enzyme-linked immunosorbent assay. Sahu SP, Alstad AD, Pedersen DD, Pearson JE.Immunoglobulin M (IgM) and G (IgG) capture enzyme-linked immunosorbent assays (ELISAs) were used as possible adjuncts to hemagglutination inhibition (HI) and virus neutralization (VN) tests to differentiate between reaction to recent exposure to eastern equine encephalomyelitis (EEE) virus and those due to prior vaccination. Serum samples were evaluated by the IgM-capture ELISA, and the results were compared with those of HI and VN tests. Of 381 serum samples, 51% (195 samples) were positive by HI test (> or = 1:40) and 54% (205 samples) were positive by VN test (> or = 1:10), but only 3...
Equine fetal kinetics: entry and retention of fetal hind limbs in a uterine horn.
Theriogenology    January 1, 1994   Volume 41, Issue 4 795-807 doi: 10.1016/0093-691x(94)90496-6
Ginther OJ, Williams D, Curran S.Transrectal ultrasonic examinations were made in 31 pregnant pony mares once a week during Months 6 to 11. Each uterine horn was divided into 3 approximately equal segments (caudal, middle, cranial). The percentage of examinations with cranial fetal presentation increased (P<0.05) progressively from 58% at Month 6 to 99% at Month 9 and was followed in all mares by entry of the fetal hind limbs into one uterine horn. The mean number of uterinehorn segments with limb parts increased (P<0.05) between each set of consecutive months from Month 6 to Month 10. Initially (Months 7 and 8), retrac...
Frequency and morpho-structural organization of the thyroid gland isthmus in horses, donkeys and small ruminants.
Bollettino della Societa italiana di biologia sperimentale    January 1, 1994   Volume 70, Issue 1-2 1-4 
Zedda M, Acone F, Bo Minelli L, Sanna L.No abstract available
Proteolytic enzymes in equine joints with infectious arthritis.
Equine veterinary journal    January 1, 1994   Volume 26, Issue 1 48-50 doi: 10.1111/j.2042-3306.1994.tb04330.x
Spiers S, May SA, Harrison LJ, Bennett D, Edwards GB.Significant amounts of collagenase and caseinase activity were detected in infected synovial fluid samples. Partial characterisation of the enzymes by gel filtration suggested that synovial fluid from cases of infectious arthritis may contain enzymes from both the synovial cells and neutrophils. This finding was also supported by analysis of sequential synovial fluid samples from 4 infected joints. In 3 joints the concentration of caseinase and in 1 joint collagenase paralleled the decline in total nucleated cell count. However, in 3 joints the concentration of collagenase remained high after ...
[The genital microflora in the stallion–microbiological study of presecretion samples from 1972 to 1991].
DTW. Deutsche tierarztliche Wochenschrift    January 1, 1994   Volume 101, Issue 1 18-22 
Scherbarth R, Pózvári M, Heilkenbrinker T, Mumme J.From 1972 to 1991, presecretion on an average of 183 stallions per year had been examined. Facultatively pathogenic germs were ascertained in 13.5% of the samples. However, the portion showed considerable annual fluctuation, as did the percentage of the different kinds of germs. In most of the cases, only minimal growth had been observed in culture. Except for the total percentage, these results are contradictory to those we found during the examination of cervical swabs of mares. In order to ascertain the importance of the respective results and to render possible a correct interpretation, th...
Animal models of Cushing’s disease.
Trends in endocrinology and metabolism: TEM    January 1, 1994   Volume 5, Issue 1 21-28 doi: 10.1016/1043-2760(94)90117-1
Kemppainen RJ, E Peterson M.Cushing's disease, defined as hyperadrenocorticism resulting from excessive secretion of pituitary ACTH, occurs spontaneously and quite commonly in dogs and horses. In dogs, as in humans, the disease is usually associated with a small tumor of the pituitary pars distalis. However, the disease may arise occasionally (dogs) or exclusively (horses) from tumors or hyperplasia of the pituitary pars intermedia. In dogs, pars intermedia tumors may arise from one of two proopiomelanocortin-containing cell types that are present in normal tissue.
The equine placenta and equine chorionic gonadotrophin–an overview.
Experimental and clinical endocrinology    January 1, 1994   Volume 102, Issue 3 235-243 doi: 10.1055/s-0029-1211287
Hoppen HO.Chorionic gonadotrophins seem to be unique for primate and equid species. Unlike primates, the equine conceptus does not implant in the maternal uterine endometrium until around day 37 of pregnancy. At this time specialized cells of the trophoblast, organized in the embryonic girdle, invade the endometrium and become established in the endometrial stroma, forming the so-called endometrial cups. This migration of girdle cells is accompanied by their morphological transformation into large decidual-like cells and by the appearance of a gonadotrophic hormone in the mare's blood. There is convinci...
[A discovery of horseshoes from the 17th century in Kiesen in Bern canton].
Schweizer Archiv fur Tierheilkunde    January 1, 1994   Volume 136, Issue 1 9-14 
Imhof U.The discovery of all four horseshoes in connection with the horse-skeleton (see IMHOF: "Discovery of a skeleton of the 17th century in Kiesen/Switzerland") made it possible to determinate its age by the radiocarbon method indirectly. The horseshoes are fully documented with pictures and scales and the findings described and discussed in detail.
Eccentrocytosis in equine red maple leaf toxicosis.
Veterinary clinical pathology    January 1, 1994   Volume 23, Issue 4 123-127 doi: 10.1111/j.1939-165x.1994.tb00922.x
Reagan WJ, Carter C, Turek J.This study documents a case of red maple leaf toxicosis in a horse, characterized by notable changes in red blood cells, specifically the formation of eccentrocytes, following ingestion of wilted […]
The relationship of daily sperm production with number of Sertoli cells and testicular size in adult horses: role of primitive spermatogonia.
Journal of reproduction and fertility    January 1, 1994   Volume 100, Issue 1 315-321 doi: 10.1530/jrf.0.1000315
Johnson L, Carter GK, Varner DD, Taylor TS, Blanchard TL, Rembert MS.The number of Sertoli cells is important in spermatogenesis as noted by significant correlations between the number of Sertoli cells and the number of germ cells observed as early as type B2 spermatogonia in the horse. However, the stage within spermatocytogenesis at which these relationships first occur is unclear. The relationships between the number of Sertoli cells and parenchymal weight and the number of germ cells during the mitosis of spermatogenesis were determined in 184 adult horses to identify the developmental stage (that is, the earliest germ cell) at which significant relationshi...
The development of Babesia (Theileria) equi (Laveran, 1901) in the gut and the haemolymph of the vector ticks, Hyalomma species.
Parasitology research    January 1, 1994   Volume 80, Issue 4 297-302 doi: 10.1007/BF02351869
Zapf F, Schein E.The development of the piroplasm Babesia equi was studied by light microscopy in the gut and the haemolymph of three different Hyalomma species during and after the nymphs had engorged on parasitaemic horses. The stock of B. equi used was isolated from a horse imported from Turkmenistan (CIS) in 1991. The existence of gamogony was identified by the occurrence of gamonts and gametes in the gut contents of the nymphs at between 3 and 4 days after infestation of the nymphs, before the ticks dropped off the experimentally infected horses. Zygotes and kinetes were observed in the intestinal cells f...
Assessment of vertebral canal diameter and bony malformations of the cervical part of the spine in horses with cervical stenotic myelopathy.
American journal of veterinary research    January 1, 1994   Volume 55, Issue 1 5-13 
Moore BR, Reed SM, Biller DS, Kohn CW, Weisbrode SE.Magnification of cervical radiographs prevents accurate interpretation of vertebral canal absolute minimum sagittal diameter (MSD) values and application of the established MSD values for diagnosis of cervical stenotic myelopathy (CSM). Variability in MSD determination in human beings, owing to radiographic magnification, is minimized by assessing a ratio of the vertebral canal diameter to the sagittal width of the vertebral body. This relative measurement technique improves the accuracy of diagnosis of cervical spinal stenosis in human beings. The MSD of the vertebral canal was determined in ...
Uremic encephalopathy in a horse.
Veterinary pathology    January 1, 1994   Volume 31, Issue 1 111-115 doi: 10.1177/030098589403100116
Bouchard PR, Weldon AD, Lewis RM, Summers BA.No abstract available
The effects of furosemide and pentoxifylline on the flow properties of equine erythrocytes: in vitro studies.
Veterinary research communications    January 1, 1994   Volume 18, Issue 5 373-381 doi: 10.1007/BF01839288
Weiss DJ, Evanson OA, Geor RJ.The effects of various concentrations of furosemide and pentoxifylline on equine RBC in vitro were evaluated to facilitate better understanding of the potential effects of these drugs on blood flow properties. Furosemide induced increased mean cell volume (MCV), increased RBC potassium concentration, increased whole blood viscosity, and decreased the RBC filtrability. These data indicate that furosemide may block the RBC membrane transport pathways resulting in potassium and water retention. The increase in size and the resultant decrease in the surface-area-to-volume ratio may have caused the...
Molecular cloning and characterization of horse DQA cDNA.
Immunogenetics    January 1, 1994   Volume 40, Issue 6 457 doi: 10.1007/BF00177830
Szalai G, Antczak DF, Gerber H, Lazary S.No abstract available
Cloning and sequencing of horse interferon-gamma cDNA.
Immunogenetics    January 1, 1994   Volume 39, Issue 6 448-449 doi: 10.1007/BF00176167
Grünig G, Himmler A, Antczak DF.No abstract available
Medically important arboviruses of the United States and Canada.
Clinical microbiology reviews    January 1, 1994   Volume 7, Issue 1 89-116 doi: 10.1128/CMR.7.1.89
Calisher CH.Of more than 500 arboviruses recognized worldwide, 5 were first isolated in Canada and 58 were first isolated in the United States. Six of these viruses are human pathogens: western equine encephalitis (WEE) and eastern equine encephalitis (EEE) viruses (family Togaviridae, genus Alphavirus), St. Louis encephalitis (SLE) and Powassan (POW) viruses (Flaviviridae, Flavivirus), LaCrosse (LAC) virus (Bunyaviridae, Bunyavirus), and Colorado tick fever (CTF) virus (Reoviridae, Coltivirus). Their scientific histories, geographic distributions, virology, epidemiology, vectors, vertebrate hosts, transm...
Imipramine and xylazine-induced ex copula ejaculation in stallions.
Theriogenology    January 1, 1994   Volume 41, Issue 5 1005-1010 doi: 10.1016/s0093-691x(05)80023-8
McDonnell SM, Odian MJ.This study is a part of our ongoing work toward developing pharmacological methods for enhancing and inducing ejaculation in stallions with ejaculatory dysfunction. We evaluated a combination treatment of imipramine hydrochloride followed 10 minutes later by xylazine hydrochloride for the induction of ex copula ejaculation. Eight pony stallions each underwent 6 treatment trials conducted at 4-day intervals. The trials were conducted in the animals' stalls, where they were observed for 90 minutes following treatment. To evaluate the effect of pretreatment sexual stimulation on the rate of ejacu...
Corpus luteal function in nonpregnant mares following intrauterine administration of prostaglandin E(2) or estradiol-17beta.
Theriogenology    January 1, 1994   Volume 42, Issue 7 1069-1083 doi: 10.1016/0093-691x(94)90855-9
Vanderwall DK, Woods GL, Weber JA, Lichtenwalner AB.The objective of this study was to test the hypothesis that intrauterine administration of prostaglandin E(2) (PGE(2)) or estradiol-17beta (E-17beta) would prolong CL function in nonpregnant mares. Nonpregnant mares were continuously infused with 240 mug/d of PGE(2), 6 mug/d of E-17beta, or vehicle (sham-treated) on Days 10 to 16 post ovulation (ovulation = Day 0), using osmotic minipumps surgically placed into the uterine lumen on Day 10 (n = 11 per group). Nonpregnant and pregnant mares served as negative and positive controls, respectively (n = 11 per group). Mares were defined as having pr...
Cardio-respiratory, haematological and biochemical parameter adjustments to exercise: effect of a probiotic in horses during training.
Veterinary research    January 1, 1994   Volume 25, Issue 4 361-370 
Art T, Votion D, McEntee K, Amory H, Linden A, Close R, Lekeux P.Two randomly distributed groups of thoroughbred horses were compared during a 12-week period for their cardio-respiratory and metabolic adjustment to strenuous exercise, training and detraining. The horses were trained following the same standardized schedule and were regularly investigated using standardized treadmill exercise tests (SET) of increasing speed. After the first SET and during the whole experimental period, a group of 6 horses received a probiotic (Bioracing) once a day while a group of 5 horses received a placebo. All other conditions were similar for both groups. During each SE...