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Topic:Equine Health

Equine health encompasses the study and management of diseases, disorders, and overall well-being of horses. It involves understanding various physiological systems, preventive care, and treatment strategies to maintain optimal health in equine populations. Common areas of focus include nutrition, infectious diseases, orthopedic conditions, and reproductive health. Research in equine health aims to advance knowledge on diagnostic methods, therapeutic interventions, and management practices that improve horse welfare and performance. This page collects peer-reviewed research studies and scholarly articles that explore the diverse aspects of equine health, offering insights into current findings and advancements in the field.
Equine ehrlichiosis.
The Veterinary clinics of North America. Equine practice    August 1, 1993   Volume 9, Issue 2 423-428 doi: 10.1016/s0749-0739(17)30408-x
Madigan JE.Equine ehrlichiosis is a seasonal disease of horses first reported in 1969. Clinical signs in horses include high fever, depression, partial hypophagia, anorexia, limb edema, petechiation, icterus, ataxia, and reluctance to move. Hematologic changes include leukopenia, thrombocytopenia, icterus, anemia, and inclusion bodies, principally in neutrophils and occasionally in eosinophils. Diagnosis is made by clinical signs and observing characteristic morulae in a blood smear with standard Wright's stain. Mortality is low unless secondary infection develops or injury occurs as a result of incoordi...
[Pilot study of the occurrence of Prototheca in fecal samples of horses].
Berliner und Munchener tierarztliche Wochenschrift    August 1, 1993   Volume 106, Issue 8 264-265 
Enders F, Weber A.Fecal samples of 146 horses were culturally investigated for occurrence of Prototheca spp. using a selective medium, developed by PORE (1973). Prototheca zopfii could be isolated in monoculture from 9 fecal samples (6.2%). The results of this pilot study show that horses too can harbour and shed Prototheca spp. in variable frequency.
Application of epidemiologic principles and methods to investigating and controlling equine infectious diseases.
The Veterinary clinics of North America. Equine practice    August 1, 1993   Volume 9, Issue 2 247-255 doi: 10.1016/s0749-0739(17)30394-2
Dargatz DA, Salman MD.Epidemiology is a tool much like any other diagnostic tool that the practitioner uses as an aid in the complete physical examination of the group of animals. It can be used to generate a specific differential diagnosis list. Epidemiology is especially useful to design a disease control and prevention program by helping to elucidate the key determinants of disease occurrence.
Characterization of virulence variants of African horsesickness virus.
Virology    August 1, 1993   Volume 195, Issue 2 836-839 doi: 10.1006/viro.1993.1440
Laegreid WW, Skowronek A, Stone-Marschat M, Burrage T.There are three clinicopathologic syndromes associated with African horsesickness (AHS) virus infection in horses. These different forms of AHS (pulmonary, cardiac, and fever forms) vary in the organs affected, the severity of lesions, time of onset of clinical signs and mortality rates. We have studied the effects of infection with three cell culture passaged variants of AHS virus in naive North American horses. One of these viruses, AHS/4SP, consistently caused the pulmonary form of AHS with rapid onset of severe pulmonary edema and 100% mortality. A second variant, AHS/9PI, resulted in sign...
African horse sickness.
The Veterinary clinics of North America. Equine practice    August 1, 1993   Volume 9, Issue 2 355-364 doi: 10.1016/s0749-0739(17)30402-9
House JA.AHS is a noncontagious vector-borne disease of Equidae caused by Orbiviruses. Species susceptibility in decreasing order is horses, mules, donkeys, and zebras. The main vectors of AHS are culicoides. The disease is endemic in sub-Saharan Africa, but epizootics have occurred outside of this area on several occasions. The most recent outbreaks outside of the endemic area were in Spain, Morocco, and Portugal between 1987 and 1990. AHS causes mortality up to 95% and is classically divided into four clinical forms: the pulmonary, cardiac, mixed, and horse fever forms. Pathologic changes are subcuta...
Clostridia-associated enterocolitis in adult horses and foals.
The Veterinary clinics of North America. Equine practice    August 1, 1993   Volume 9, Issue 2 411-421 doi: 10.1016/s0749-0739(17)30407-8
Traub-Dargatz JL, Jones RL.A review of the literature describing clostridia-associated enterocolitis is presented. The bacteria, their toxins, and possible factors that interact to contribute to the pathogenesis of enterocolitis are described. Clinical signs associated with clostridia-associated enterocolitis, methods of diagnosis, treatments, and preventive strategies are discussed.
Ultrasonographic measurement of stallion accessory sex glands and excurrent ducts during seminal emission and ejaculation.
Biology of reproduction    August 1, 1993   Volume 49, Issue 2 267-273 doi: 10.1095/biolreprod49.2.267
Weber JA, Woods GL.Accessory sex gland and excurrent duct activity of 10 stallions was visualized with transrectal ultrasonography during seminal emission and ejaculation. First and last penile urethral contractions were defined as the start (0 sec) and end of ejaculation, respectively. Duration of ejaculation (n = 63 ejaculations) averaged 6.15 +/- 2.98 sec. Penile urethral contractions occurred an average of 6.2 +/- 2.2 times per ejaculation. Right bulbourethral glands (n = 19 ejaculations) alternated repeatedly from ovoid to flattened, irregular shapes during ejaculation. Cross-sectional area of right bulbour...
Role of decreased plasma volume in hematocrit alterations during incremental treadmill exercise in horses.
The American journal of physiology    August 1, 1993   Volume 265, Issue 2 Pt 2 R404-R408 doi: 10.1152/ajpregu.1993.265.2.R404
McKeever KH, Hinchcliff KW, Reed SM, Robertson JT.Six intact (IN) and six splenectomized (SP) mares were subjected to an incremental exercise test to examine the role of decreases in plasma volume (PV) in the changes in hematocrit (Hct) normally seen with exercise. Each horse underwent an incremental exercise test in which it ran on a treadmill up a fixed incline of 6 degrees. The test started at a speed of 4 m/s, and speed was increased 1 m/s each min until heart rate reached a plateau. Blood samples were obtained at rest and at the end of the 4, 5, 6, and 7 m/s steps of the exercise test. Resting PV was greater (P < 0.05) in the IN group...
Synteny mapping in the horse using horse-mouse heterohybridomas.
Animal genetics    August 1, 1993   Volume 24, Issue 4 257-260 doi: 10.1111/j.1365-2052.1993.tb00308.x
Williams H, Richards CM, Konfortov BA, Miller JR, Tucker EM.In a study of 35 horse-mouse heterohybridoma cell lines, synteny in the horse was found between LDHB, PEPB and IGF1 and between NP, MPI and IDH2. A synteny between ADA and PEPC was also indicated. The loci for horse immunoglobulin light chain (IgL) genes and for LDHA were independent.
Biomechanical considerations in the treatment of navicular disease.
The Veterinary record    July 31, 1993   Volume 133, Issue 5 109-114 doi: 10.1136/vr.133.5.109
Wright IM, Douglas J.In recent years much attention has been paid to vascular studies of the navicular bone in health and disease; however, the relative importance of these studies has overshadowed biomechanical factors which may yet prove to be of importance. This paper outlines the pertinent anatomy, and discusses current concepts in the aetiology and pathogenesis of the disease. It describes the treatment regimens which are based on biomechanical considerations and compares the results of some currently employed techniques. All aspects of navicular disease remain controversial. This paper is not intended to rev...
Hematuria and leptospiruria in a foal.
Journal of the American Veterinary Medical Association    July 15, 1993   Volume 203, Issue 2 276-278 
Bernard WV, Williams D, Tuttle PA, Pierce S.A Thoroughbred foal that was born after 305 days of gestation was referred 6 hours after birth. On initial examination, the foal was alert, but weak and unable to stand. Heart rate was 150 beats/min, respiratory rate was 48 breaths/min, and rectal temperature was 33 C. Leukocytosis was detected (26,000 WBC/microliters). Dysuria and passage of red urine was observed approximately 30 hours after admission. Urine collected by free catch had a 3+ reaction for blood on dipstick analysis. Examination of Warthin Starry-stained sections of allantochorion revealed organisms morphologically characterist...
Peritonitis in horses: 67 cases (1985-1990).
Journal of the American Veterinary Medical Association    July 15, 1993   Volume 203, Issue 2 284-288 
Hawkins JF, Bowman KF, Roberts MC, Cowen P.Peritonitis was diagnosed in 67 horses between 1985 and 1990: 14 horses developed septic peritonitis after intestinal rupture, 25 horses developed peritonitis after abdominal surgery, and 28 horses had peritonitis not associated with intestinal rupture or abdominal surgery. Forty of 67 horses (59.7%) did not survive. Nonsurvivors had higher heart rates (P = 0.01), RBC count (P = 0.039), serum creatinine concentration (P = 0.036), PCV (P = 0.007), and anion gap (P = 0.005); lower venous blood pH (P = 0.002); and a greater number of bacterial species cultured from peritoneal fluid samples (P = 0...
Standing laparoscopic laser technique for ovariectomy in five mares.
Journal of the American Veterinary Medical Association    July 15, 1993   Volume 203, Issue 2 279-283 
Palmer SE.Laparoscopic laser instrumentation and endoscopic stapling techniques were used to perform 10 unilateral ovariectomy procedures on 5 standing Thoroughbred mares. In all instances, mares had a clinically normal reproductive tract and estrous cycle, and ovariectomy was performed to eliminate regular estrous behavior. All procedures were accompanied by minimal trauma and uncomplicated postoperative recovery. Mares were able to resume normal activity 2 weeks after surgery. Regular estrous behavior was eliminated in all 5 mares, although 1 mare continued to have signs of estrous behavior occasional...
Horsepower from a horse.
Nature    July 15, 1993   Volume 364, Issue 6434 195 doi: 10.1038/364195a0
Stevenson RD, Wassersug RJ.No abstract available
Renal tubular acidosis in a mare.
The Veterinary record    July 10, 1993   Volume 133, Issue 2 43-44 doi: 10.1136/vr.133.2.43
van der Kolk JH, Kalsbeek HC.No abstract available
Reconstitution of horse heart myoglobin with hemins methylated at 6- or 7-positions: a circular dichroism study.
Biochimica et biophysica acta    July 10, 1993   Volume 1164, Issue 2 133-137 doi: 10.1016/0167-4838(93)90239-n
Santucci R, Ascoli F, La Mar GN, Pandey RK, Smith KM.The reconstitution kinetics of horse heart myoglobin, as met-cyano derivative, with two synthetic hemins in which the 6- or the 7-propionate is replaced by a methyl group, has been investigated by circular dichroism, in order to gain information on the heme re-orientation process following the heme insertion into the globin pocket. The results obtained confirm that the preferred heme orientation places the sole propionate into the position occupied by the 6-propionate in the crystal structure, supporting the importance of the salt bridge occurring between this propionate and the basic CD3 resi...
Diagnosis of grass sickness by ileal biopsy.
The Veterinary record    July 3, 1993   Volume 133, Issue 1 7-10 doi: 10.1136/vr.133.1.7
Scholes SF, Vaillant C, Peacock P, Edwards GB, Kelly DF.Ileal biopsies were obtained from 18 horses with grass sickness, 15 horses with other alimentary disease and three horses without gastrointestinal disease. Samples of small intestine were also obtained from nine cases of obstruction due to small intestinal strangulation. Histological examination revealed that severe enteric neuropathy in the absence of other significant morphological changes was confined to the horses with grass sickness.
Dorsal displacement of the soft palate in neonatal foals.
Equine veterinary journal    July 1, 1993   Volume 25, Issue 4 329-332 doi: 10.1111/j.2042-3306.1993.tb02975.x
Altmaier K, Morris EA.No abstract available
Uterine transport of prostaglandin E(2)-releasing simulated embryonic vesicles in mares.
Theriogenology    July 1, 1993   Volume 40, Issue 1 13-20 doi: 10.1016/0093-691x(93)90337-5
Vanderwall DK, Woods GL, Weber JA, Lichtenwalner AB.Transrectal ultrasonography was used to test the hypothesis that prostaglandin E(2) (PGE(2)) would increase the uterine transport of simulated embryonic vesicles in mares. Uterine transport of PGE(2)-releasing (PGE) vesicles, vehicle-releasing (sham) vesicles, and equine embryos was contrasted on Day 12 or Day 13 post ovulation. In Experiment 1, there was no difference (P>0.10) in transport of PGE vesicles, sham vesicles, Day-12 embryos, and Day-12 embryos after cervical manipulation (n = 3 per group). In Experiments 2 and 3, respectively, transport of PGE and sham vesicles was contrasted with...
Hemodialysis for treatment of oxytetracycline-induced acute renal failure in a neonatal foal.
Journal of the American Veterinary Medical Association    July 1, 1993   Volume 203, Issue 1 105-107 
Vivrette S, Cowgill LD, Pascoe J, Suter C, Becker T.Acute renal failure in a 4-day-old foal secondary to oxytetracycline toxicosis was treated by hemodialysis. Oxytetracycline had been administrered as treatment for forelimb flexor tendon contracture. Conservtive treatment with fluids, furosemide, and dopamine partially alleviated serum electrolyte concentration imbalances, but was ineffective in promoting diuresis or decreasing azotemia. Three hemodialysis treatments over 4 days were administered, after which the clinical appearance of the foal improved, and biochemical and electrolyte values returned to within reference ranges. The nephrotoxi...
Generation and partial characterization of an eosinophil chemotactic cytokine produced by sensitized equine mononuclear cells stimulated with Strongylus vulgaris antigen.
Veterinary immunology and immunopathology    July 1, 1993   Volume 37, Issue 2 135-149 doi: 10.1016/0165-2427(93)90061-8
Dennis VA, Klei TR, Chapman MR.Supernatants generated by stimulation of peripheral blood mononuclear cells (PBMC) from Strongylus vulgaris sensitized or immunized ponies were assayed in vitro for eosinophil chemotactic activity (ECA) using the filter system in blind well chambers. The supernatants from these cultures were chemotactic for eosinophils, but not for neutrophils. Supernates from cultures of unsensitized PBMC stimulated with S. vulgaris antigen were not chemotactic for eosinophils. ECA was first detected in culture supernatants after 1.5 h of incubation and was dependent on both antigen and PBMC concentrations, b...
Comparison of five tests for the serologic diagnosis of myiasis by Gasterophilus spp. larvae (Diptera: Gasterophilidae) in horses and donkeys: a preliminary study.
Medical and veterinary entomology    July 1, 1993   Volume 7, Issue 3 233-237 doi: 10.1111/j.1365-2915.1993.tb00682.x
Escartin-Peña M, Bautista-Garfias CR.Sera from 41 horses and 159 donkeys, from twelve States of México, were tested to ascertain anti-Gasterophilus circulating antibodies by double immunodiffusion (DD), counterimmunoelectrophoresis (CIE), indirect haemagglutination (IH), thin layer immunoassay (TIA) and diffusion-in-gel ELISA (DIG-ELISA) methods using crude somatic antigen from third instar larvae of G. intestinalis (DeGeer). At necropsy, 33/41 horses and 24/159 donkeys were found to be parasitized by G. intestinalis and/or G. nasalis (L.). Gasterophilus intestinalis was the species most commonly found in the equines. Analysis o...
Clinical pharmacokinetics of amikacin in hypoxic premature foals.
Equine veterinary journal    July 1, 1993   Volume 25, Issue 4 276-280 doi: 10.1111/j.2042-3306.1993.tb02963.x
Green SL, Conlon PD.The pharmacokinetics of amikacin, administered iv at 7 mg/kg, every 8 h, were evaluated over the first 48 h of hospitalisation in 7 critically ill hypoxic premature foals and compared with those in 8 full-term nonhypoxic critically ill neonatal foals. The pharmacokinetic data were used to calculate dosage schedules that would maintain the plasma amikacin concentrations in individual foals within a target range of > or = 15 micrograms/ml but < 30 micrograms/ml for peak values and < or = 3 micrograms/ml for trough values. The results indicated a statistically significant increase in the amikacin...
ELISA screening with GC-MS confirmation of the tranquilizer chlorprothixene administered in subtherapeutic doses to horses.
Journal of pharmaceutical and biomedical analysis    July 1, 1993   Volume 11, Issue 7 569-575 doi: 10.1016/0731-7085(93)80007-n
Delbeke FT, Teale P, Debackere M, Houghton E.A commercially available generic promazine ELISA kit is available which shows cross-reactivity for the tranquilizer chlorprothixene (CPT). The ELISA test readily detects the presence of CPT or its metabolites in equine urine for up to 24 h after the i.v. and i.m. administration of sub-therapeutic doses (4.5 mg) to three horses. Maximum concentrations (CPT equivalents) are obtained 2 h after i.v. dosing. No distinct concentration peak values are observed after i.m. administration. Following solid-phase extraction, confirmation of CPT and its metabolites by electron impact mass spectrometry afte...
Histoplasmosis in horses.
Journal of comparative pathology    July 1, 1993   Volume 109, Issue 1 47-55 doi: 10.1016/s0021-9975(08)80239-3
Rezabek GB, Donahue JM, Giles RC, Petrites-Murphy MB, Poonacha KB, Rooney JR, Smith BJ, Swerczek TW, Tramontin RR.Histoplasmosis was diagnosed in nine horses during 1986-1990. The infection with Histoplasma capsulatum caused granulomatous placentitis and abortion in one mare in the 7th month of gestation and three mares in the 10th month. Four newborn foals died from severe granulomatous pneumonia within a few days of birth; and a weanling thoroughbred developed granulomatous pneumonia and lymphadenitis at 5 months of age.
Paravertebral thoracolumbar anaesthesia in 10 horses.
Equine veterinary journal    July 1, 1993   Volume 25, Issue 4 304-308 doi: 10.1111/j.2042-3306.1993.tb02968.x
Moon PF, Suter CM.The caudal border of the last rib was used as a reliable point of orientation while performing paravertebral thoracolumbar anaesthesia (PTLA) on 10 horses undergoing standing flank laparotomy. The local anaesthetic in all horses was 2% lidocaine. The PTLA procedure was completed in 9.8 +/- 1.8 mins (mean +/- sd). Sedation was provided by a combination of intravenous morphine with xylazine or detomidine. Overall analgesia, provided by the combination of PTLA and sedation, was rated as excellent in 2 horses and good in 6 horses. In the remaining 2 horses, overall analgesia was rated as fair beca...
Hypersensitivity of horses in British Columbia to extracts of native and exotic species of Culicoides (Diptera: Ceratopogonidae).
Journal of medical entomology    July 1, 1993   Volume 30, Issue 4 657-663 doi: 10.1093/jmedent/30.4.657
Anderson GS, Belton P, Kleider N.Six horses from British Columbia severely affected by Culicoides hypersensitivity, a seasonal dermatitis caused by the bites of Culicoides spp., were inoculated intradermally with extracts of six species or forms of Culicoides from British Columbia, United States, and Israel. Two native and four exotic species were thought to cause the disease in their own geographical area. The horses developed large welts within 20 min after injection of any of the six extracts, indicating an immediate (type I) reaction. The skin reactions caused by each extract peaked at or after 24 h, indicating an additio...
Intra-operative cardiac arrest: routes to recovery.
Equine veterinary journal    July 1, 1993   Volume 25, Issue 4 259-260 doi: 10.1111/j.2042-3306.1993.tb02959.x
Hodgson DS, Steffey EP.No abstract available
Development of a competitive enzyme-linked immunosorbent assay for detection of bovine, ovine, porcine, and equine antibodies to vesicular stomatitis virus.
Journal of clinical microbiology    July 1, 1993   Volume 31, Issue 7 1860-1865 doi: 10.1128/jcm.31.7.1860-1865.1993
Afshar A, Shakarchi NH, Dulac GC.Two competitive (C) enzyme-linked immunosorbent assays (ELISAs) were developed for the detection of antibodies to vesicular stomatitis virus (VSV) in animal sera. The assays are based upon the availability of polyclonal antibodies (PAbs) from mouse ascitic fluids prepared against the New Jersey (NJ) and the Indiana (IN) VSV serotypes. The assays were performed by the immobilization of VSV-NJ and VSV-IN antigens on a solid phase (microtiter plate). Appropriately diluted test serum mixed with an equal volume of serotype-specific PAb was allowed to incubate in the presence of the relevant VSV ant...
Use of ultrasound in horses for diagnosis of left dorsal displacement of the large colon and monitoring its nonsurgical correction.
Veterinary surgery : VS    July 1, 1993   Volume 22, Issue 4 281-284 doi: 10.1111/j.1532-950x.1993.tb00398.x
Santschi EM, Slone DE, Frank WM.During a 28 month period, 82 horses with clinical signs of abdominal pain were examined for left dorsal displacement of the large colon (LDDLC) using percutaneous ultrasound. Left dorsal displacement of the large colon was diagnosed when a gas echo dorsal to the spleen obliterated the dorsal splenic border, or when the colon was observed lateral to the spleen. In 42 horses, ultrasound confirmed a diagnosis of LDDLC and 40 horses had no evidence of LDDLC. There were five false negative results and no false positives. In four horses with LDDLC, the colon was displaced between the spleen and body...