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Topic:Equine Health

Equine health encompasses the study and management of diseases, disorders, and overall well-being of horses. It involves understanding various physiological systems, preventive care, and treatment strategies to maintain optimal health in equine populations. Common areas of focus include nutrition, infectious diseases, orthopedic conditions, and reproductive health. Research in equine health aims to advance knowledge on diagnostic methods, therapeutic interventions, and management practices that improve horse welfare and performance. This page collects peer-reviewed research studies and scholarly articles that explore the diverse aspects of equine health, offering insights into current findings and advancements in the field.
Glyoxalase 2 deficiency in the erythrocytes of a horse: 1H NMR studies of enzyme kinetics and transport of S-lactoylglutathione.
Archives of biochemistry and biophysics    December 1, 1991   Volume 291, Issue 2 291-299 doi: 10.1016/0003-9861(91)90137-8
Rae C, Board PG, Kuchel PW.In mammalian red blood cells the metabolism of methylglyoxal, and some alpha-ketoaldehydes, takes place via two, generally, highly active enzymes, glyoxalase 1 and 2. The 1H NMR spin-echo spectra of horse erythrocytes, and the various reactants in the glyoxalase system, were characterized as a prelude to obtaining series of spectra in time courses of methylglyoxal metabolism. We characterized the kinetics of the enzyme system in red cells from a normal horse and also from one which had very low activity of glyoxylase 2. The kinetics of the reaction scheme, with methylglyoxal as the starting su...
Standing surgical procedures of the foot.
The Veterinary clinics of North America. Equine practice    December 1, 1991   Volume 7, Issue 3 695-722 doi: 10.1016/s0749-0739(17)30495-9
Honnas CM.Several surgical conditions affecting the foot can be successfully managed with the horse standing. Many factors affect the clinician's choice of whether to perform surgery with the horse standing or anesthetized. Temperament or pregnancy of the horse and economics may influence the decision to perform surgery with the horse standing. This article discusses several foot conditions that can be treated successfully in the ambulatory horse.
Standing surgery.
The Veterinary clinics of North America. Equine practice    December 1, 1991   Volume 7, Issue 3 485-722 
No abstract available
Bone biopsy in the horse. 3. Normal histomorphometric data according to age and sex.
Zentralblatt fur Veterinarmedizin. Reihe A    December 1, 1991   Volume 38, Issue 10 793-797 doi: 10.1111/j.1439-0442.1991.tb01080.x
Savage CJ, Tidd LC, Ostblom LC, Melsen F, Jeffcott LB.Histomorphometrical analysis of bone biopsies from the wing of ilium in 35 clinically normal horses are reported according to age. The biopsies were collected from 20 mixed-bred foals (mean age 6 +/- 1 months) and 15 older horses (mean age 73 +/- 62 months). No gender differences were found in the group of foals examined, but a significant difference (p less than 0.001) in a number of the primary measurements occurred between them and the older horses. The parameters which altered with age were the extent of osteoid surface (OS/BS), the extent of resorption (erosion) surface (ES/BS), the osteo...
The pharmacology of local anesthetics.
The Veterinary clinics of North America. Equine practice    December 1, 1991   Volume 7, Issue 3 489-500 doi: 10.1016/s0749-0739(17)30482-0
Day TK, Skarda RT.Understanding of the pharmacology of local anesthesia is important for selection of a local anesthetic for use in equine standing surgery. In general, the action potential is inhibited by local anesthetics by preventing the influx of sodium ions across the axonal membrane. The physicochemical properties of each local anesthetic determine the onset of action, potency, and duration of action. Procaine, chlorprocaine, lidocaine, and mepivacaine are the local anesthetics still used clinically in horses; lidocaine is the most widely used. The future of equine local anesthesia may see the introducti...
Possible importance for laminitis research of recent studies on substances influencing the differentiation of cultured keratinocytes.
Zentralblatt fur Veterinarmedizin. Reihe A    December 1, 1991   Volume 38, Issue 10 721-727 doi: 10.1111/j.1439-0442.1991.tb01071.x
Ekfalck A, Jones B, Obel N.After a survey of the state of laminitis research the authors conclude that none of the present concepts of the pathogenesis of laminitis unequivocally explains the basic clinical and morphological observations in this disease. There is therefore reason to consider the advances that have been made during the last decades in respect to the influence of various substances on the differentiation of cultured skin keratinocytes. The technique is available for studying hoof keratinocytes in a comparable way. Relevant literature on cultured skin keratinocytes is surveyed. Some of the results from exp...
Medetomidine in horses.
The Veterinary record    November 23, 1991   Volume 129, Issue 21 476 doi: 10.1136/vr.129.21.476
Jones P, Hoare C.No abstract available
Cloning and characterization of gene TNF alpha encoding equine tumor necrosis factor alpha.
Gene    November 15, 1991   Volume 107, Issue 2 319-321 doi: 10.1016/0378-1119(91)90333-7
Su XZ, Morris DD, McGraw RA.We report the molecular cloning and nucleotide sequence of the equine gene encoding tumor necrosis factor alpha. The 2610-bp genomic sequence was derived from three overlapping polymerase chain reaction products.
Arterioureteral fistula in a colt.
Equine veterinary journal    November 11, 1991   Volume 23, Issue 6 483-484 doi: 10.1111/j.2042-3306.1991.tb03767.x
Latimer FG, Magnus R, Duncan RB.No abstract available
Effect of an isoxsuprine-resin preparation on blood flow in the equine thoracic limb.
The Veterinary record    November 9, 1991   Volume 129, Issue 19 427-429 doi: 10.1136/vr.129.19.427
Deumer J, de Haan F, Tulp MT, van den Hoven R.The effects of an oral isoxsuprine-resin preparation on the blood flow in the thoracic limb of seven horses was determined by thermography. Treatment with the oral resin preparation resulted in increased skin temperatures compared with the non-medicated controls. The maximal temperature differences, 2.2 degrees C for the horses treated with 0.9 mg/kg and 1.8 degrees C for the horses treated with 1.2 mg/kg, occurred four hours after dosing. Plasma total isoxsuprine, determined in three horses, was detectable two hours after oral dosing and maximal eight hours after dosing, but free isoxsuprine ...
Facial swelling in cattle and horses.
The Veterinary record    November 9, 1991   Volume 129, Issue 19 436 doi: 10.1136/vr.129.19.436
Arbuckle JB.No abstract available
Comparison of the sedative effects of medetomidine and xylazine in horses.
The Veterinary record    November 9, 1991   Volume 129, Issue 19 421-423 doi: 10.1136/vr.129.19.421
Bryant CE, England GC, Clarke KW.The sedative effects in horses of the new alpha 2 agonist medetomidine were compared with those of xylazine. Four ponies and one horse were treated on separate occasions with two doses of medetomidine (5 micrograms/kg bodyweight and 10 micrograms/kg bodyweight) and with one dose of xylazine (1 mg/kg bodyweight) given by intravenous injection. Medetomidine at 10 micrograms/kg was similar to 1 mg/kg xylazine in its sedative effect but produced more severe and more prolonged ataxia, and one animal fell over during the study. Medetomidine at 5 micrograms/kg produced less sedation but a similar deg...
Diagnosis of pulmonary valve endocarditis in a horse.
Equine veterinary journal    November 1, 1991   Volume 23, Issue 6 479-482 doi: 10.1111/j.2042-3306.1991.tb03766.x
Nilsfors L, Lombard CW, Weckner D, Kvart C.No abstract available
Radiographic, high detail radiographic, microangiographic and histological findings of the distal portion of the tarsus in weanling, young and adult horses.
Equine veterinary journal    November 1, 1991   Volume 23, Issue 6 413-421 doi: 10.1111/j.2042-3306.1991.tb03753.x
Laverty S, Stover SM, Bélanger D, O'Brien TR, Pool RR, Pascoe JR, Taylor K, Harrington T.Clinical radiographic (LM and D35L-P1MO views), high detail radiographic, microangiographic and histological findings of the distal portion of the tarsus of 16 horses (five weanling, four young and six adult), without known clinical histories, were evaluated to determine the sensitivity of clinical radiographs for the detection of abnormalities in the distal tarsus and the prevalence of abnormalities in this population. Clinical radiographic and high detail radiographic abnormalities were observed in at least 30 per cent of the tarsi examined. Statistical agreement between observations from cl...
Immunotherapy of cryptosporidiosis in immunodeficient animal models.
The Journal of protozoology    November 1, 1991   Volume 38, Issue 6 98S-100S 
Perryman LE, Bjorneby JM.Immunotherapy for persistent infection caused by Cryptosporidium parvum was attempted in two immunodeficient animal models. BALB/c Athymic (nude) mice were infected with two oral doses of 2 x 10(7) C. parvum oocysts, and subsequently treated with monoclonal antibody (MAb) 17.41 that neutralizes sporozoites and merozoites. Persistent infection was established in all exposed mice. Daily oral treatment with MAb 17.41 for 10 days significantly reduced (p less than 0.005) the number of C. parvum organisms observed by microscopic study of intestinal tracts of infected mice. Young horses with severe ...
[Adenoma of the pigmented epithelium of the iris with endothelialization and descemetization in the horse].
Zentralblatt fur Veterinarmedizin. Reihe A    November 1, 1991   Volume 38, Issue 9 652-659 
Daicker B, Gywat L, Keller M, Spiess B, Brückner R.The authors describe peculiar tumors with brown-white piebald anterior surface, which had grown bilaterally from the corpora nigra (C.N.) of an adult horse and occluded the pupils. The surgical procedure for removing the larger tumor and the postoperative treatment are described. The findings by light and electron microscopy suggest that the tumor represent a so-called adenoma of the iris pigment epithelium. The white patches on its surface consist of newly formed Descemet-like material produced by displaced corneal endothelial cells, which have probably grown on the tumor after contact with t...
Actinobacillus spp. and related bacteria in infected wounds of humans bitten by horses and sheep.
Journal of clinical microbiology    November 1, 1991   Volume 29, Issue 11 2535-2538 doi: 10.1128/jcm.29.11.2535-2538.1991
Peel MM, Hornidge KA, Luppino M, Stacpoole AM, Weaver RE.We describe the isolation of Actinobacillus lignieresii and an A. equuli-like bacterium from an infected horse-bite wound in a 22-year-old stable foreman and A. suis from a bite injury in a 35-year-old man who had been attacked by a horse. A. lignieresii was also isolated in pure culture from an infected sheep-bite wound in a rural worker. These species of the genus Actinobacillus are primarily associated with animals and animal diseases and are rarely isolated from humans. The purpose of this report is to raise awareness of the possible occurrence of Actinobacillus spp. in bite wounds inflict...
Measurements of the accuracy of clinical diagnoses of equine neurologic disease.
Journal of veterinary internal medicine    November 1, 1991   Volume 5, Issue 6 332-334 doi: 10.1111/j.1939-1676.1991.tb03146.x
Mayhew IG.Parameters for the accuracy of clinical diagnosis of neurologic diseases in the horse were determined from 210 horses in which a definitive pathologic diagnosis was confirmed. The overall efficiency of diagnosis for all diseases was 0.95 although the validity varied from 0.79 to 1.00, the sensitivity varied from 0.73 to 0.95, and the specificity varied from 0.88 to 1.00 for individual disease categories. Equine protozoal myeloencephalitis was overdiagnosed, whereas Eastern equine encephalomyelitis, equine degenerative myeloencephalopathy, and traumatic neurologic disease were underdiagnosed. T...
Blood gas analyses on equine blood: required correction factors [see comment].
Equine veterinary journal    November 1, 1991   Volume 23, Issue 6 410-412 doi: 10.1111/j.2042-3306.1991.tb03752.x
Fedde MR.Correction factors have been determined to obtain the best estimates of PO2, PCO2 and pH in equine blood with standard blood gas and pH electrodes. There was a significant difference between the PO2 readings for tonometred blood of most horses and the equilibrating gas. Thus, if the PO2 electrode is calibrated with a gas, an electrode correction factor should be obtained by tonometring a blood sample from each horse. This factor was not dependent on packed cell volume. No such correction is required for the PCO2 electrode. If the animal's temperature differs from that of the analyser, the PO2,...
The body condition of feral ponies on Assateague Island.
Equine veterinary journal    November 1, 1991   Volume 23, Issue 6 453-456 doi: 10.1111/j.2042-3306.1991.tb03760.x
Rudman R, Keiper RR.The summer body condition of 47 adult feral ponies on Assateague Island (off the coast of Maryland, USA) was assessed in June 1988 using a visual body condition scoring system. Winter body condition for 36 of the ponies was assessed in February and March, 1989. The ponies were categorised by gender, reproductive status and location on the island, and body condition scores of the ponies in each category were then compared by statistical analyses. No significant seasonal differences were found in the body conditions of the ponies. However, body condition of stallions was better than that of mare...
A technique for transrectal ultrasonography of stallions during ejaculation.
Theriogenology    November 1, 1991   Volume 36, Issue 5 831-837 doi: 10.1016/0093-691x(91)90349-i
Weber JA, Woods GL.A technique was developed in which the accessory sex glands of stallions were visualized with transrectal ultrasonography during ejaculation. The technique was judged to be effective, since 10 of 11 stallions were trained to tolerate transrectal ultrasonography during ejaculation; they ejaculated during 195 of 200 attempts, and acceptable visualization of their accessory sex glands and excurrent ducts occurred during 97 of 195 ejaculations. Sixty-five percent (89 136 ) of the recordings were successful for stallions that weighed more than 300 kg, whereas 14% (8 59 ) of the recordings were succ...
Co-culture of day-5 to day-7 equine embryos in medium with oviductal tissue.
Theriogenology    November 1, 1991   Volume 36, Issue 5 815-822 doi: 10.1016/0093-691x(91)90347-g
Freeman DA, Butler JE, Weber JA, Geary RT, Woods GL.Oviductal and uterine embryos were collected from mares at 5 to 7 days following ovulation 1) to evaluate the effects of oviductal tissue explants on in vitro growth and development of equine embryos and 2) to study the morphologic development of equine embryos in culture. Embryos were incubated for 5 days in a medium (control group) or in medium supplemented with oviductal tissue explants (co-culture group). Embryos were evaluated and the media changed daily. Following 5 days in culture, 10 10 (100%) control embryos and 27 29 (93%) co-cultured embryos had doubled in diameter. All embryos that...
Endoscopic examination of normal paranasal sinuses in horses.
Veterinary surgery : VS    November 1, 1991   Volume 20, Issue 6 418-423 doi: 10.1111/j.1532-950x.1991.tb00350.x
Ruggles AJ, Ross MW, Freeman DE.The frontal, caudal maxillary, and rostral maxillary sinuses of 10 equine cadavers were examined endoscopically, and the findings were confirmed by sinusotomy. Similar endoscopic examinations were performed in five conscious, adult horses by using sedation and local anesthesia. Useful portals of entry for the arthroscope in adult horses were: for the frontal sinus, 60% of the distance in a lateral direction from midline to the medial canthus and 0.5 cm caudal to the medial canthus; for the caudal maxillary sinus, 2 cm rostral and 2 cm ventral to the medial canthus; and for the rostral maxillar...
Influence of age on neutrophil function in foals.
Equine veterinary journal    November 1, 1991   Volume 23, Issue 6 466-469 doi: 10.1111/j.2042-3306.1991.tb03763.x
Wichtel MG, Anderson KL, Johnson TV, Nathan U, Smith L.Functional activities (phagocytosis and killing) of neutrophil leucocytes (NL) and immunoglobulin G concentrations were evaluated in six healthy foals from birth to 6 months of age. Peripheral blood NL were reacted with Streptococcus equisimilis in 20 per cent pooled equine serum for 30, 60 and 90 mins and functional activities of NL were determined using a fluorochrome microassay. Values for foal NL function were compared with those of healthy adult horses (n = 28). Foal neutrophil function was influenced by age. Killing capacity of NL decreased, whereas phagocytic capacity increased, until 1...
The isolated perfused equine skin flap. Preparation and metabolic parameters.
Veterinary surgery : VS    November 1, 1991   Volume 20, Issue 6 424-433 doi: 10.1111/j.1532-950x.1991.tb00351.x
Bristol DG, Riviere JE, Monteiro-Riviere NA, Bowman KF, Rogers RA.A model for the study of equine cutaneous physiology, pharmacology, and toxicology was developed. Four 4 x 12 cm and twenty-one 6 x 12 cm single-pedicle axial pattern skin flaps based on the caudal superficial epigastric artery, and eight 6 x 12 cm flaps based on the saphenous artery and medial saphenous vein, were raised and sutured in a tubed configuration. On day 2, each flap was removed, the artery was cannulated, and the flap was perfused with a modified Krebs-Ringer's albumin-based medium for at least 6 hours. Flap viability was assessed by glucose use, lactate production, and histologic...
Femoral head ostectomy in horses and cattle.
Veterinary surgery : VS    November 1, 1991   Volume 20, Issue 6 453-458 doi: 10.1111/j.1532-950x.1991.tb00354.x
Squire KR, Fessler JF, Toombs JP, Van Sickle DC, Blevins WE.Femoral head ostectomy was performed in six horses, three ponies, and four cattle for treatment of fractures of the femoral capital physis, coxofemoral luxation, fractured acetabulum, or severe degenerative joint disease. The procedures were performed via a cranial approach that did not involve osteotomy of the greater trochanter. A dorsal approach for femoral head ostectomy via osteotomy of the greater trochanter was evaluated in three healthy adult ponies. Three animals (2 ponies, 1 calf) were euthanatized within a month and one horse was euthanatized at year 2 due to postoperative complicat...
Morphine and etorphine: XIV. Detection by ELISA in equine urine.
Journal of analytical toxicology    November 1, 1991   Volume 15, Issue 6 305-310 doi: 10.1093/jat/15.6.305
Stanley S, Jeganathan A, Wood T, Henry P, Turner S, Woods WE, Green M, Tai HH, Watt D, Blake J.We have raised antibodies to morphine and etorphine and developed one-step enzyme-linked immunosorbent assays (ELISA) for these drugs as part of a panel of post race tests for drugs in racing horses. These tests are simple, can be completed in 2 h, and can be read by visual inspection. The morphine ELISA has an I50 for morphine of about 1.5 ng/mL, while the etorphine ELISA has an I50 for etorphine of 250 pg/mL. Cross-reactivity studies show that the antimorphine antibody cross-reacts well with levorphanol, hydromorphone, and oxycodone, while the anti-etorphine antibody showed no cross-reactivi...
Measurement of cardiac dimensions with two-dimensional echocardiography in the living horse.
Equine veterinary journal    November 1, 1991   Volume 23, Issue 6 461-465 doi: 10.1111/j.2042-3306.1991.tb03762.x
Voros K, Holmes JR, Gibbs C.Two-dimensional echocardiography (2DE) was performed on 22 unsedated Thoroughbred and part Thoroughbred horses weighing between 411 and 650 kg to establish normal reference values for 2DE measurements. Animals stood during examinations performed with a 3.5 MHz mechanical sector transducer using various transducer positions and tomographic planes. Right ventricular diameter (RVD), ventricular septal thickness (VSTh), aortic diameter (AoD), area of the chordal lumen of the left ventricle (CTA), left ventricular diameter (LVD) and left atrial diameter (LAD) were determined at ventricular end-dias...
The genetic basis of equine allergic diseases. 1. Chronic hypersensitivity bronchitis.
Equine veterinary journal    November 1, 1991   Volume 23, Issue 6 457-460 doi: 10.1111/j.2042-3306.1991.tb03761.x
Marti E, Gerber H, Essich G, Oulehla J, Lazary S.The genetic influence on chronic hypersensitivity bronchitis (CB) was investigated in families at two studs and among half-siblings of three affected and three non-affected sires at several farms. The family members at the two studs were born and raised under the same conditions, whereas the half-siblings were kept individually under very different conditions and were exposed to various environmental factors. The diagnosis was based on long-term observations and multiple clinical examinations at each of the two studs. In the half-sibling group, the diagnosis was based on the individual history...
Immune-mediated thrombocytopenia in horses infected with equine infectious anemia virus.
Journal of virology    November 1, 1991   Volume 65, Issue 11 6242-6251 doi: 10.1128/JVI.65.11.6242-6251.1991
Clabough DL, Gebhard D, Flaherty MT, Whetter LE, Perry ST, Coggins L, Fuller FJ.An adult horse infected with a virulent, cell culture-adapted strain of equine infectious anemia virus (EIAV) developed cyclical thrombocytopenia in which the nadir of platelet counts coincided with peak febrile responses. In order to investigate the mechanism of thrombocytopenia during acute febrile episodes, four adult horses were experimentally infected with the wild-type Wyoming strain of EIAV. Platelet counts decreased from baseline as rectal temperature increased. Serum reverse transcriptase activity increased above background levels in all horses, coincident with increase in rectal temp...