Equine health encompasses the study and management of diseases, disorders, and overall well-being of horses. It involves understanding various physiological systems, preventive care, and treatment strategies to maintain optimal health in equine populations. Common areas of focus include nutrition, infectious diseases, orthopedic conditions, and reproductive health. Research in equine health aims to advance knowledge on diagnostic methods, therapeutic interventions, and management practices that improve horse welfare and performance. This page collects peer-reviewed research studies and scholarly articles that explore the diverse aspects of equine health, offering insights into current findings and advancements in the field.
Science (New York, N.Y.)September 21, 1962
Volume 137, Issue 3534 979-980 doi: 10.1126/science.137.3534.979
STEINBERG S, BOTELHO S.Congenital myotonia, similar to that which has been reported in humans and in goats, is here reported for the first time in another species. Evidence is given to show (i) that the myotonic phenomenon is present despite complete block of neuromuscular transmission; (ii) prior to injection of curare, synchronous activity of muscle fibers may result not only from ephaptic stimulation of neighboring fibers but also from reflex firing; and (iii) water deprivation does not relieve the myotonia.
PLUMMER G.A VIRUS was isolated in monkey kidney tissue cultures from the fæces of 13 of 290 horses held in the stables of the Wellcome Research Laboratories. One of these strains was selected for investigation. Rabbit hyperimmune serum prepared against it and possessing a neutralizing titre of 1/4,000 neutralized all 12 remaining isolates to the same titre.
TURK RD, UECKERT BW, BELL RR.No signs of intoxication were seen in horses dosed with thiabendazole at either 200 mg. or 400 mg. per kg. body-weight. 17 horses were dosed with the drug at a level of 100 mg. per kg. These horses had a mean egg count of 1, 296 e.p.g. before treatment; all were negative for strongyle eggs by the 7th day after treatment. 3 of these horses were killed and few or no strongyles were found; an untreated control animal killed at the same time had many thousands of strongyle worms. Thiabendazole was effective when given either by stomach tube or when mixed in the feed.
INGRAM DG.A method is described for the quantitative measurement of the reactions between sensitized cells and horse complement and between alexinated cells and conglutinin. The method is laborious but its application has allowed the determination of the optimal times of the reactions at various temperatures. The results obtained in these experiments indicate that the alexinated configuration with which conglutinin and immuno-conglutinin react is not one of the recognized intermediates formed during the process of immune haemolysis.
Aref S.A study of the migration of fourth stage larvae of the parasite Strongylus vulgaris in the intestinal arteries of the horse is presented. It is established, that the larvae migrate along the arteries in almost straight lines. It is suggested that this is primarily due to their ability to sense the curvature of the vessel wall, and not, as might have been expected, because of an ability to sense the direction of blood flow. A larva will sometimes alter its direction of motion when encountering a small off-branching artery. This behaviour suggests, that the migration of S. vulgaris larvae can be...
Velineni S, DeNegri R, Artiushin SC, Timoney JF.Streptococcus zooepidemicus (Sz) and its clonal derivative Streptococcus equi (Se) share greater than 96% DNA identity and elicit immune responses to many shared proteins. Identification of proteins uniquely targeted by the immune response to each infection would have diagnostic value. Objective: The aim of the study was to compare serum antibody responses of horses infected by Se or Sz. Methods: Antibody levels were measured to panels of recombinant proteins of Sz and Se in sera of horses and ponies before and after experimental and naturally occurring invasive infections by these organisms. ...
Watson ED.The mechanisms that permit maternal tolerance of the conceptus allograft during early pregnancy in the mare have not been investigated. Embryos and endometria were collected from mares 14 days after ovulation and cultured for 20.5 h. The effect of addition of culture supernatant on incorporation of [3H]thymidine by equine peripheral blood lymphocytes was studied. Culture supernatant from endometrium of nonpregnant mares did not affect lymphocyte blastogenesis, but supernatant from both embryos and endometrium of pregnant mares reduced concanavalin A (Con A)- and phytohemagglutinin-induced blas...
Butler DG.Mailed questionnaires administered to employers of graduates and to graduates of the Ontario Veterinary College in 2000 and 2001, 7 to 10 months after convocation, surveyed new graduate performance in the workplace. Proficiency at 9 species-specific (in 4 practice contexts) and 7 nonspecies-specific clinical activities were rated as "high," "some," or "low." Fifteen nonvocation-specific attributes, reflecting interpersonal, communication, and business skills, and the new graduate's competence to do his/her job were rated as "very good," "good," or "poor." Ninety or more percent of employers re...
Mirck MH, Franken P.Experimental infections using 600,000 infective larvae of Strongyloides westeri were carried out in seven worm-free Shetland ponies, four foals and thee yearlings. In the foals, the prepatent period varied from ten to fourteen days, the patent period ranging from forty-three to eighty-three days. Within approximately two months after infection, a decrease in the concentration of haemoglobin and an increase in the beta-globulin fraction of the protein pattern of the serum, practically coinciding with the maximum S. westeri faecal egg counts, were recorded. In the yearlings, the prepatent period...
Rollin B.This research paper discusses the responsibility of humans towards animals they own, focusing specifically on the concept of the “unwanted horse”. The author argues that once a human acquires an […]
Kudrimoti S, Machin J, Arojojoye AS, Awuah SG, Eisenberg R, Fenger C, Maylin G, Lehner AF, Tobin T.Based on structural similarities and equine administration experiments, Barbarin, 5-phenyl-2-oxazolidinethione from Brassicaceae plants, is a possible source of equine urinary identifications of aminorex, (R,S)-5-phenyl-4,5-dihydro-1,3-oxazol-2-amine, an amphetamine-related US Drug Enforcement Administration (DEA) controlled substance considered illegal in sport horses. We now report the synthesis and certification of d -barbarin to facilitate research on the relationship between plant barbarin and such aminorex identifications. D -barbarin synthesis commenced with production of d -2-oxo-2-phe...
Collier MA, Haugland LM, Bellamy J, Johnson LL, Rohrer MD, Walls RC, Bartels KE.This study was performed to investigate the effects of holmium:yttrium-aluminum-garnet (Ho:YAG) laser energy on articular cartilage and subchondral bone adjacent to traumatically created cartilage lesions in a continuous weight-bearing model. The 2.1-microns wavelength was delivered efficiently and precisely in hand-controlled contact and near-contact hard tissue arthroscopic surgery in a saline medium. Bilateral arthroscopy was performed on normal antebrachiocarpal and intercarpal joints of four adult horses. One hundred twenty traumatic lesions were created on three weight-bearing articular ...
van Dyk E, Immelman A, van Heerden JS.After isolation of Pseudomonas aeruginosa from endometrial biopsies of 6 mares they were treated with amikacin sulphate. Three were treated by intra-uterine application of the drug, in one the drug was given by intramuscular injection, in another the intravenous route was used while in the last mare simultaneous local and intravenous treatment was applied. An intra-uterine Tris-EDTA instillation preceeded the uterine amikacin instillations to aid in the breakdown of the capsule around the bacterium. Serum concentrations of amikacin were determined after intravenous and intramuscular administra...
McIlwraith CW.The article discusses the key findings and discussions from the fifth Welfare and Safety of the Racehorse Summit. This summit presented several ways in which data collection and analysis can […]
Wood AK, Sehgal CM, Reef VB.In a feasability study, a technique for constructing 3-dimensional sonographic images of the superficial digital flexor tendon (SDFT) was established in 6 clinically normal horses and applied to 7 horses with injured SDFT. Two-dimensional B-mode sonographic images were recorded on videotape as the sonographic transducer was manually moved along the palmar aspect of the metacarpal region. Selected videofields were digitized, and 3-dimensional images were constructed, using a computer work station and dedicated software program. The 3-dimensional images were of high quality and presented qualita...
Madsen K, Martens A, Haspeslagh M, Meulyzer M, Gustafsson K.Medical grade honey (MGH) has been introduced as a protective measure against surgical site infections in equine surgery, but the effect on suture material has not been investigated. Objective: To evaluate the effect of MGH on the tensile properties of three synthetic absorbable suture materials. Methods: In vitro experiments. Methods: Ten strands of Polydioxanone USP 2 (PD2), Polyglactin 910 USP 2 (PG2) and Polyglecaprone USP 2-0 (PC2-0) were incubated 1, 7, 14, 21 and 28 days in MGH, phosphate-buffered saline (PBS), equine plasma (EP) and MGH mixed with equine plasma (HP). Mechanical testi...
Hornof WJ, Stover SM, Koblik PD, Arthur RM.The research article discusses a study on the use of oblique dorsal views in detecting stress fractures in horses who participate in races. The aim of the researchers was to […]
Williams S, Scott P.Meal contaminated by Datura stramonium seeds at the rate of 0.5% by weight was fed to two horses. Both horses showed clinical signs of depression, anorexia, weight loss, rapid heart and respiration rates, mydriasis, polyuria, polydipsia and diarrhoea. Both recovered with treatment. Maize screenings contaminated by the seeds had been used in the manufacture of the meal.
Tåmová B, Stumpa A, Zakopal J, Vĕzníková D, Mensík J.Equine influenza occurred in Czechoslovakia 14 years after the last epizootic in horses that had returned from abroad. Six strains A (Heq1Neq1) antigenically related to, but not identical with, strain A/eq/Praha/56 were isolated from 10 washings. Seroconversion was demonstrated with paired sera, but the antibody increase was more marked against the newly isolated strain.
Bondesson U, Johansson IM.This study demonstrates the development of a method using gas chromatography-mass spectrometry for determining nefopam, a non-narcotic pain reliever that is sometimes abused in horse doping, in equine plasma. Background […]
Whan G, Runciman RJ, Hurtig M.Whole bone in vitro biomechanical compressive testing can be complicated by three factors: sample asymmetry, heterogeneous material properties, and unknown effective centroid location. Methods: The technique presented here facilitates the calculation of effective centroid position, modulus of elasticity and equivalent uniform strain magnitude for a cross section of bone from a simple whole bone compressive test. Simplification of section response to load is achieved through a combination of linear beam and simple planer geometry theory. The technique requires three longitudinal strain gauges b...
Bishop J, Heffron B, Taddei L, Benoit M, Hurt L, Costello S, Gross M, Negrusz A.Clenbuterol (CLE) is used in horses as a bronchodilator and for its anabolic steroid-like effects. CLE is a Class 3 drug according to current Association of Racing Commissioners International (ARCI) Uniform Classification Guidelines. The Racing Medication and Testing Consortium recommended a urine CLE threshold of 140 pg/mL after careful scientific review of the results of studies describing the disposition of CLE in the horse and this threshold was adopted by the ARCI. Enzyme-linked immunosorbent assay was previously used to screen samples for CLE in Illinois, but could not detect such low co...
