Omneity® Pellets
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Topic:Horses
"Horses" is a broad topic that encompasses various aspects of equine biology, behavior, and management. This category includes studies on the anatomy, physiology, and genetics of horses, as well as their behavior, nutrition, and care. Research in this area may also cover the historical and cultural significance of horses, their roles in agriculture, sport, and therapy, and the challenges associated with their conservation and welfare. The page aggregates peer-reviewed research articles and scholarly studies that explore the multifaceted relationships between humans and horses, examining both scientific and socio-economic perspectives.
Cardiopulmonary effects of ephedrine in halothane-anesthetized horses. The cardiopulmonary effects of intravenous (i.v.) administration of the sympathomimetic drug ephedrine during two different levels of halothane anesthesia [end-tidal concentration of 1.37% (light anesthesia) and 2.1% (deep anesthesia)] were studied in eight horses. Anesthesia was induced and maintained using only halothane in O2. Ventilation was controlled to maintain a Paco2 of 38-42 mmHg. Following instrumentation and stabilization of the horse at the halothane concentration being studied, baseline measurements of cardiac output (Q), arterial blood pressure (AP), pulmonary artery pressure, h...
Absorption of two trimethoprim/sulphonamide combinations from the uterus of pony mares. Plasma drug concentrations were measured after two commercially available potentiated sulphonamides, trimethoprim and sulfadoxine and trimethoprim and sulphadiazine, were infused daily for 2 and 3 days, respectively, into the uteri of pony mares which had been mated before ovulation. Intravenous administration of trimethoprim and sulfadoxine allowed uterine absorption of trimethoprim (23-43%) and sulfadoxine (29-34%) to be calculated. After intra-uterine administration trimethoprim and sulphadiazine were detected in the milk of a lactating mare. In order to maintain plasma concentrations likel...
Effect of dietary linolenic acid on endotoxin-induced thromboxane and prostacyclin production by equine peritoneal macrophages. In laboratory animals, the incorporation of alpha linolenic acid or other n-3 series fatty acids into the diet results in marked changes in cell membrane composition as well as arachidonic acid metabolism. The purpose of the present study was to determine whether endotoxin-induced thromboxane A2 (TxA2) and/or prostacyclin (PGI2) production by equine peritoneal macrophages was altered by feeding horses a diet containing 8% linseed oil as a source of alpha linolenic acid for 8 weeks. Peritoneal macrophages were cultured in vitro in the presence of endotoxin (LPS) (0.5-500 ng/ml) or calcium ionop...
Pharmacokinetic disposition of an immediate-release aminophylline and a sustained-release theophylline formulation in the horse. The pharmacokinetic disposition of theophylline was determined by high-performance liquid chromatographic analysis of plasma samples from six healthy, adult horses following the administration of intravenous aminophylline (dosed at 9.94 mg/kg as theophylline), immediate-release aminophylline tablets (dosed at 9.94 mg/kg as theophylline), and sustained-release theophylline tablets (dosed at 20 mg/kg). The elimination rate constant (lambda z), apparent volume of distribution (Vz), and clearance (Cl) determined by compartmental analysis of the intravenous data were 0.07 +/- 0.01 h-1, 0.80 +/- 0.0...
The management of open joint injuries. The prognosis for returning horses with open joint injuries to athletic function is most closely related to the duration of the injury prior to treatment. Prompt diagnosis and appropriate therapy should yield a favorable result. Delayed diagnosis or inappropriate therapy that allow the wound to progress to an infected state makes the likelihood of return to athletic function poor. Refractory joint infection can occur despite early diagnosis and prompt appropriate therapy. The development of these infections is undoubtedly increased by tissue loss and gross contamination. Appropriate antibiotic...
Delayed wound closure and scar revision. Delayed closure is an underutilized technique that can produce a good cosmetic result in lower leg wounds and can significantly shorten the healing time. To be successful, the surgeon should be able to utilize tension-relieving techniques and manage dead space. Scar revision should be limited to simple elliptical excision or modifications thereof until experience is developed. Sliding skin flaps, Z-plasties, and W-plasties are used infrequently and require adequate preoperative planning.
Heart weight and running ability. The weight of the heart as determined by dissection techniques was compared with liveweight and total muscle weight in different types of horses and dogs as adults and during growth. With increasing body size both within and between species, heart weight forms a lesser proportion of liveweight and of total muscle weight. Heart weight forms a greater proportion of liveweight in Thoroughbreds and Greyhounds (breeds noted for high speed running) than in other less fleet members of their species and Greyhounds have greater heart weights relative to total muscle weight than other dogs.
Skin grafting of the horse. Free autogenous skin grafting of the horse is indicated for wounds too large to heal by contraction and epithelization. Techniques of pinch, punch, tunnel, and sheet grafting are described. Allografting and storage of skin for delayed grafting are discussed.
A hemolytic assay for the measurement of equine complement. A hemolytic assay was developed for the measurement of functional equine complement activity. The assay utilizes antibody sensitized chicken erythrocytes as the target cell and was specific for classical pathway (antibody dependent) complement activity. The assay was found to be reproducible and more sensitive than previous reports using other species of target cells. Total serum complement (CH50) values were determined for five mares and their foals and followed over a period of 3 months.
Cross-neutralizing and subclass characteristics of antibody from horses with equine infectious anemia virus. Antibody responses in horses with equine infectious anemia virus (EIAV) were examined to determine their cross-neutralizing capacity. Antibodies induced by infection with any of six biologically cloned variants of EIAV cross-neutralized multiple variants from the group. Anti-EIAV antibody was found in both the IgG and IgG(T) subclasses in plasmas with virus-neutralizing activity and the majority of antiviral antibody was of the IgG(T) subclass. Depletion of IgG(T) did not increase the neutralization indexes of either neutralizing or non-neutralizing plasma samples.
Accuracy of prediction of the liveweight of horses from body measurements. Fifty-three horses, all but two of them over two years of age and varying in type, sex and liveweight (230 to 707 kg) were weighed and seven different body measurements were recorded in duplicate by a single operator. The best overall prediction of liveweight using an equation with two variables was found to be: liveweight (kg) = (umbilical girth [cm])1.78 X (length of body from tuber ischii to elbow [cm]0.97/3011). This equation had an adjusted R2 value of 94.9 per cent and was derived from the pooled data, because differences of sex, type and weight did not significantly affect the relations...
Thin-layer chromatographic screening procedure for some drugs in horse plasma. A thin-layer chromatographic screening procedure for some basic, neutral and acidic drugs was developed using 3 ml of horse plasma. Chloroform-2-propanol (95:5, v/v) was used as the extraction solvent. The drugs were identified by a high-performance thin-layer chromatographic plate and spraying successively with some detection reagents. In this study, the extraction recovery rates and the detection limits were determined at the same time.
Influence of clenbuterol on mucociliary transport in healthy horses and horses with chronic obstructive pulmonary disease. The mucociliary tracheal transport rate and clearance index were measured in 16 healthy horses and 16 horses suffering from chronic obstructive pulmonary disease. A marker, Indian ink in syrup, was placed in the mucus layer of the interior wall of the trachea, just in front of the carina, and its displacement was measured after 30 and 60 minutes. The same procedure was repeated 30 minutes after the intravenous administration of 0.8 microgram clenbuterol/kg bodyweight. In the diseased horses the mucociliary transport rate was significantly lower than in the healthy horses. After clenbuterol adm...
[Neonatal hemolytic icterus in foals. A study of antibodies in colostrum and serum]. Investigations for the presence of antibodies to red blood cell antigens were carried out in equine colostrum and serum. Material from 181 mares without clinical disease was tested. The object was to obtain information on the number of mares producing antibodies capable of inducing haemolytic disease in newborn foals. Of the mares 2.8% was positive for haemolysins. These mares are expected to be a risk for haemolytic disease. In addition agglutinating antibodies were identified in 39.2 per cent of the mares examined. It is not known whether or not these antibodies constitute a hazard for the f...
Staphylectomy for treatment of dorsal displacement of the soft palate in two foals. Dorsal displacement of the soft palate associated with dysphagia and aspiration pneumonia was diagnosed in 2 young foals. The displacement appeared to be congenital. Clinical signs associated with the condition were resolved after staphylectomy. Dorsal displacement of the soft palate is usually recognized in adult animals as an upper respiratory tract disease, but may be a contributing factor to dysphagia and lower respiratory tract disease in young animals.
Internal fixation of a transverse scapular neck fracture in a filly. A 3-week-old Standardbred filly had a non-weightbearing forelimb lameness caused by scapular neck fracture. The fracture was repaired with 2 dynamic compression plates placed 90 degrees to each other. A 10-hole 4.5-mm narrow dynamic compression plate was placed on the cranial aspect of the scapular spine, and a 10-hole 3.5-mm dynamic compression plate was placed caudal to the scapular spine. One year after surgery, the filly was not lame when exercising in the pasture, and muscle atrophy was not evident on the affected limb. Eighteen months after surgery, the filly was in race training with no...
Class-specific and polyvalent enzyme-linked immunosorbent assays for detection of antibodies to Borrelia burgdorferi in equids. Class-specific and polyvalent ELISA were developed to detect IgM antibody or total immunoglobulins to Borrelia burgdorferi in equine sera. Analyses of 122 serum specimens, collected during 1985 from horses and ponies in tick-infested areas of Connecticut, revealed IgM antibody in 41 (34%) samples; titration end points ranged from 1:160 to 1:2,560. In polyvalent ELISA, 73 (16%) of 454 serum specimens contained IgM and/or IgG antibody. Seropositivity was highest (32%) for blood samples collected during May. Both ELISA procedures had comparable sensitivities.
Methods of stimulating acupuncture points for treatment of chronic back pain in horses. Horses with chronic back pain of 2 to 108 months' duration were treated using acupuncture (n = 15), laser acupuncture (n = 15), or injection acupuncture (n = 15). Horses were treated once a week for 8 treatments (mean) with needle acupuncture, 11 treatments with laser acupuncture, or 9 treatments with injection acupuncture. After treatment, 37 horses had alleviation of clinical signs of pain and could train and compete: 13 horses treated with needle acupuncture; 11 horses treated with laser acupuncture; and 13 horses treated with injection acupuncture. Seemingly, the 3 types of acupuncture wer...
Cervical hyperplasia with prolapse in a mare. Cervical hyperplasia with prolapse through the vulvar lips was documented in a mare. Postmortem examination indicated that the mass originated from the cervical wall. The surface of the prolapsed mass had histologic features of normal cervix. Cervical hyperplasia can be considered in a list of differential diagnoses in cases of prolapse of the internal genitalia in mares.
[The pattern of riding injuries]. During the period from 1.1. to 31.12.1988, 104 patients with injuries resulting from riding or other forms of direct contact with horses were examined and treated in a casualty department in the County of Vejle. Antecedent data from these patients were collected. The majority of injuries occurred on falling from the horse and involved particularly the upper part of the body. The commonest injuries were bruises which did not require special treatment. The relationships between concussion, fracture of the humerus and fracture of the clavicle and riding were investigated by odds ratio. Much fewer...
Field efficacy of ivermectin, fenbendazole and pyrantel embonate paste anthelmintics in horses. Three anthelmintic pastes were compared in terms of their ability to suppress the output of parasite eggs in the faeces of 108 grazing horses at four sites in Britain; the horses were treated once with either ivermectin, fenbendazole or pyrantel. At each site, the horses grazed together throughout the trials which took place during the summers of 1985 and 1986. The median periods before parasite eggs reappeared in faeces were 70 days for ivermectin, 14 days for fenbendazole and 39 days for pyrantel embonate. Geometric mean faecal egg counts in the groups treated with ivermectin and pyrantel we...
Influence of limb temperature on sensory nerve conduction velocity in horses. Sensory nerve conduction velocity was measured in the lateral palmar nerve of 8 horses. The limb temperature was manipulated by external means and monitored. Alterations in the nerve conduction velocity related to limb temperature variation were identified at both increased and decreased temperatures. These were quantified and a mean value of 2.15 +/- 0.2 m/s/degree Celsius was determined. The effect of altered limb temperature should be considered in nerve conduction velocity determinations.
Immunohistochemical investigation of the distribution of immunoglobulins G, A and M within the anterior uvea of the normal equine eye. Distribution of the immunoglobulin (Ig) classes G, A and M within the anterior uvea of eight clinically normal equine eyes was examined using indirect immunoperoxidase labelling. Increased staining intensity of stromal IgG and IgA was observed within the ciliary processes, the iris stroma being relatively free of immunoglobulin. This may reflect anatomical variation in the permeability of the uveal microvasculature to lipid insoluble plasma macro-molecules. Intracellular IgG and IgA were observed within the non-pigmented ciliary epithelium in seven and four of the eight eyes respectively, alth...
The arterial supply of the navicular bone in the normal horse. An arteriographic and histological study of the arterial blood supply of 35 navicular bones, from 19 adult horses with no clinical or radiographical signs of navicular disease, is described. The arteries enter the navicular bone from four directions: distal, proximal, medial, and lateral. The navicular bone can be divided into areas which receive arteries from one, two, or three directions, whereas the distal supply covers the largest part of the navicular bone. The distal arteries enter the navicular bone through the nutrient foramen which contains loose connective tissue, nutrient vessels an...
Intradermal challenge of Icelandic horses with extracts of four species of the genus Culicoides. Twenty-three Icelandic horses were challenged with extracts of four species of biting midges: Culicoides pulicaris, C chiopterus, C obsoletus and C impunctatus. Fourteen of the tested horses were affected with summer eczema. The horses were challenged intradermally with 0.1 ml of whole-body extracts of midges at a concentration of 0.01 or 0.005 per cent weight/volume. The skin reactions were measured after 30 minutes, 60 or 180 minutes and four, 24 and 48 hours after injection. Antigen titration showed that the reaction was dependent on the antigen concentration. Eight of nine unaffected horse...
