Omneity® Pellets
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Topic:Horses
"Horses" is a broad topic that encompasses various aspects of equine biology, behavior, and management. This category includes studies on the anatomy, physiology, and genetics of horses, as well as their behavior, nutrition, and care. Research in this area may also cover the historical and cultural significance of horses, their roles in agriculture, sport, and therapy, and the challenges associated with their conservation and welfare. The page aggregates peer-reviewed research articles and scholarly studies that explore the multifaceted relationships between humans and horses, examining both scientific and socio-economic perspectives.
Comparison of uterine protein content and distribution of bacteria in the reproductive tract of mares after intrauterine inoculation of Haemophilus equigenitalis or Pseudomonas aeruginosa. Two groups of 3 mares were inoculated with Haemophilus equigenitalis or Pseudomonas aeruginosa on the 1st day of estrus. Uterine flushing samples were recovered on day 3 of estrus and day 8 after ovulation for each cycle. Mares were killed 22, 25, and 30 days after inoculation with P aeruginosa and 45, 46, and 49 days after inoculation with H equigenitalis. Pseudomonas aeruginosa was recovered from the uterus of 2 mares 48 hours after inoculation. Although the initial flushing sample of 1 of these 2 mares had an increased total protein concentration, there appeared to be little difference betw...
Effect of electromyography on serum creatine kinase values in clinically normal dogs and horses. The effect of needle electromyography (EMG) on serum creatine kinase (CK) activity was determined, using clinically normal dogs (males and females; n = 8) and horses (females; n = 8). All animals appeared normal on EMG evaluation. Serum CK was measured before and 4, 24, and 48 hours after EMG. Except for a single 24-hour sample in a dog, the animals did not have abnormally increased serum CK activity after EMG. For dogs and horses, mean values were increased, but within normal range at 4 and 24 hours and returned to base-line values by 48 hours after EMG. For dogs, but not for horses, these CK...
Seasonal variation of histomorphologic features of equine endometrium. The effect of seasonal morphologic variation of equine endometrium on histologic interpretation of periglandular fibrosis was investigated in 5 mares. Endometrial tissue was procured monthly and examined microscopically for the degree of periglandular fibrosis. A prognostic category for each mare was based on the mean number of fibrotic foci per linear field of 5.5 mm. It was found that seasonal changes reflected in endometrial glands and stroma influenced quantitative assessment of fibrosis. This occasionally resulted in a change in the assigned prognostic category. Marked nonseasonal variati...
Critical test evaluations of oxfendazole and trichlorfon: effectiveness of a paste formulation in the horse. Critical tests were performed on 6 horses to evaluate the antiparasitic effectiveness of oxfendazole given in combination with trichlorfon in a paste formulation. Treatments were given orally as a single dose. The rates of active ingredient administration were 2.5 and 40 mg/kg of body weight for oxfendazole and trichlorfon, respectively. The combined activities of the 2 antiparasitic compounds proved 100% efficacious in the removal of adult Strongylus vulgaris, S edentatus, Oxyuris equi, and Parascaris equorum. Fourth stage O equi, and 2nd and 3rd instars of Gasterophilus nasalis also were com...
Kinetic study of CO and O2 binding to horse heart myoglobin reconstituted with synthetic hemes lacking methyl and vinyl side chains. Carbon monoxide- and oxygen-binding rates and affinities were measured for horse heart myoglobins reconstituted with synthetic hemes lacking peripheral methyl and vinyl groups. There is an apparent correlation between heme size and ligand specificity, i.e. larger m values (ratios of CO vs O2 association rates, l'/k') with smaller hemes. However, this correlation broke down with the most dealkylated heme. This is interpreted as resulting from protein conformational changes altering the steric crowdedness at the O2-binding site. Spectral properties and autoxidation rates also corroborate this vi...
Chemotactic properties and protein of equine uterine fluid. Forty uterine fluid samples were obtained from 4 mares classified as resistant to uterine bacterial infection. The uterus of each mare was flushed with 50 ml of saline solution during estrus and diestrus of successive estrous cycles. Bacteria or fungi were isolated from 4 samples, and 7 additional samples were obtained from a mare with active intrauterine infection. Fluid volumes obtained during estrus (means = 40.3 +/- 11 ml) tended to be greater than those recovered during diestrus (means = 36.8 +/- 7.9 ml), but the difference was not significant. Concentrations and yields of protein in reco...
Vitamin K3-induced renal toxicosis in the horse. Renal toxicosis attributable to vitamin K3 (menadione sodium bisulfite) was suspected in 5 young adult horses in which acute renal failure developed following parenteral administration of vitamin K3 at the manufacturers' recommended dosages. Renal disease was subsequently induced experimentally in 5 of 6 horses by administration of vitamin K3 at manufacturers' recommended dosages. Signs of renal disease in the clinical patients as well as in the horses treated experimentally included renal colic, hematuria, azotemia, and electrolyte abnormalities consistent with acute renal failure. Two clinic...
Lacerations of the equine eye: a review of 48 cases. Perforating corneal wounds in horses have a better prognosis than wounds that involve both cornea and sclera. Sharp objects tend to produce more isolated corneal wounds and have a better prognosis than do wounds produced by blunt objects. The records of 43 horses that sustained penetrating wounds of the cornea were reviewed. In addition, the surgical approach and postoperative wound management is described. The report attempts to provide more information regarding the management of ocular trauma in horses.
Conjunctival fungal flora in horses, cattle, dogs, and cats. Conjunctival swab specimens were obtained from both eyes of 43 horses, 25 cows, 50 dogs, and 25 cats without keratitis or other ophthalmologic problems. Fungi were isolated from 95% of the horses, 100% of the cows, 22% of the dogs, and 40% of the cats. Aspergillus spp were isolated from 56% of the horses, 12% of the cows, 8% of the cats, and none of the dogs. Penicillium spp and Cladosporium spp were isolated ubiquitously. Collectively, 28 species from 209 isolants were identified.
Preliminary X-ray investigation of enzyme substrate complexes of horse muscle phosphoglycerate kinase. Crystals of horse muscle 3-phosphoglycerate kinase have been grown in the presence of a wide variety of substrates using either potassium tartrate or polyethylene glycol as a precipitant. In those grown from polyethylene glycol, two related crystal forms have been obtained by varying the nature of the substrates present in the crystallization medium. In order to obtain one of these forms, form B, the presence of the substrate 3-phosphoglycerate appears to be essential. The two crystal forms are not interconvertible by simple diffusion experiments and the crystals grown in the absence of 3-phos...
Stride characteristics of horses competing in Grand Prix jumping. An investigation was made of the stride characteristics of horses jumping 2 obstacles during a Grand Prix competition. One obstacle was a picket fence and rail 1.3 m high (fence 2), and the other was a coop and rail 1.52 m high (fence 11). Thirteen distance and 22 timing measurements of 17 horses were extracted from high-speed films, using computer-aided analysis. These data were used to compare takeoff and landing of the lead and nonlead legs, the thoracic limbs and pelvic limbs, and fence 2 and fence 11. Paired t-tests were used to compare means and a stepwise regression analysis was done fo...
Inbreeding and reproductive performance in standardbred horses. The relationship between inbreeding and both conception and foaling rates in Standardbred horses (trotters and pacers) was examined for 1194 breeding years. There was a statistically significant (P less than 0.05) trend for conception and foaling rates to decrease with increased inbreeding; however, this relationship accounted for less than 2 percent of the variation. Additionally, the relationship between reproductive performance and inbreeding was not consistent between trotters and pacers. For trotters (F = 0.103) there was a trend for an increase in conception and foaling rates with increa...
Blood metabolite profiles of broodmares and foals. Serum amino acid profiles and other serum characteristics of broodmares and their foals wee studied. Compared with mares, foals had significantly higher concentrations of serum leucine, threonine, aspartic acid, asparagine, glutamic acid, glutamine, proline and tyrosine, glucose, cholesterol, creatinine and phosphorus. Foals had significantly less serum histidine, glycine, cystine, taurine, protein and urea nitrogen. Lysine and/or methionine supplementation of pregnant and lactating broodmare diets were conducted. Changes in serum amino acid profiles caused by dietary amino acid supplemented w...
Perilla ketone toxicity: a chemical model for the study of equine restrictive lung disease. Perilla ketone was assessed for its usefulness as a model of equine restrictive pulmonary disease. Three ponies were given 18 mg/kg bodyweight synthetic perilla ketone in dimethyl-sulphoxide. Within 24 h of administration, respiratory rate, peak inspiratory and expiratory flow rates and minute volume were increased. By 48 h there was a significant decrease in tidal volume, and blood pH and base excess were also decreased but not outside normal limits. At necropsy there was congestion and oedema of the lungs. Histologically there was diffuse alveolar injury but no evidence of significant obstru...
Bone strain in the equine tibia: inertia as a cause of the presupport peak. Strain tracings obtained from the tibial cortex of walking ponies reveal peaks in the principal tension and compression strains occurring immediately before and after the support phase. Evidence is presented that the presupport peak is caused by inertial forces.
Relationship between paired plasma and serum viscosity and plasma proteins in the horse. The relationship between paired plasma and serum viscosity measurements and plasma proteins, including fibrinogen, were compared in 106 horses with both normal and abnormal serum protein levels. There is a highly significant positive correlation between serum viscosity and total serum proteins and total globulin levels. The difference between plasma and serum viscosity correlated well with clottable fibrinogen concentration. Albumin levels showed a negative correlation with plasma and serum viscosity, globulins and fibrinogen. Simultaneous estimation of serum and plasma viscosity improves the ...
Ivermectin and an ivermectin-penicillin combination: a comparison of anthelmintic efficacy in horses. Ivermectin given IM at 200 micrograms/kg, alone or in combination with procaine penicillin G at 600 IU/kg, to 20 randomly selected young horses of various breeds reduced fecal strongyle egg counts from 400-4100 epg (avg greater than 1000) pretreatment to zero 7 days posttreatment. There were no systemic or injection-site reactions, either immediate or delayed, in any of the horses.
Esophageal anastomosis in two foals. Esophageal anastomosis was performed on 2 foals after resecting a midcervical stricture. Nasogastric tube alimentation and antibiotic therapy allowed these foals to recover, and they matured to useful performing horses. These cases demonstrated a feasible and successful surgical management regimen for the strictured esophagus.
The effects of naloxone on endotoxic and hemorrhagic shock in horses. The effects of naloxone on the cardiovascular, hematologic and metabolic derangements associated with endotoxic and hemorrhagic shock were studied in unanesthetized horses. In the first of 3 experiments blood glucose and lactate levels, hematocrit, white, red and differential white cell counts, rectal temperature and clinical signs were obtained before and after endotoxin (10 micrograms/Kg) administration in 5 horses. In the second experiment, two groups of 3 horses received either intravenous naloxone (0.04 mg/Kg) or saline, 7 minutes prior to endotoxin. In a third experiment two groups of 4 ...
Arterial oxygen and carbon dioxide tensions in conscious laterally recumbent ponies. Six adult ponies were trained calmly to assume and maintain left lateral recumbency without the use of sedative or immobilising agents. During a 30 min recumbent period, pHa, arterial oxygen and carbon dioxide tensions (PaO2 and PaCO2) and heart and respiratory rates were monitored at regular intervals to evaluate ventilatory response. Overall, there were no statistically significant differences found between mean control and recumbent or final standing values. When lightweight ponies were compared to heavyweight ponies, only mean PaO2 at 10 mins recumbency was different. This information supp...
Serum concentration of penicillin in the horse after repeated intramuscular injections of procaine penicillin G alone or in combination with benzathine penicillin and/or phenylbutazone. Twenty-one adult horses were randomly assigned into 7 groups of 3 and were treated for 5 days with procaine penicillin G, benzathine penicillin , or phenylbutazone in various combinations and dosage schedules. Serum concentration of penicillin was measured serially over a 7-day period. The highest mean peak serum concentration was 2.06 micrograms/ml. Comparable peak values were seen 2 to 4 hours after administration of 22,000 IU of procaine penicillin G/kg of body weight given once or twice daily. A minimum serum concentration of 0.25 micrograms/ml was selected as adequate for efficacy against...
Cellular constituents of clinically normal foal bronchoalveolar lavage fluid during postnatal maturation. Bronchoalveolar lavage was performed 5 times, sequentially, on 3 healthy foals when each was between 2 and 63 days of age. Total and differential counts were performed on recovered cells. The lungs of foals less than 19 days of age contained few alveolar macrophages recoverable by bronchoalveolar lavage. This number increased sharply during the first 2 to 3 weeks of life, but remained relatively constant subsequently. Approximately 86% of the alveolar cells in the lungs of foals up to 3 weeks of age were alveolar macrophages. During the first 2 months of life, this number decreased to approxim...
Uterine culture in mares. A guarded, sterile swab is used to obtain samples for uterine culture. With the mare in stocks, the tail bandage and the perineum washed, the culture rod is introduced into the vagina with a gloved hand. After the rod is guided through the cervix, the guard cap is dislodged and the swab is rubbed along the endometrium, after which the rod is extracted. Samples for uterine culture should only be obtained during full estrus. Swabs should be directly plated onto agar within 2 hours of collection. Blood agar is appropriate for initial screening, but use of specialized types of agar expedites ident...
