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Topic:Horses

"Horses" is a broad topic that encompasses various aspects of equine biology, behavior, and management. This category includes studies on the anatomy, physiology, and genetics of horses, as well as their behavior, nutrition, and care. Research in this area may also cover the historical and cultural significance of horses, their roles in agriculture, sport, and therapy, and the challenges associated with their conservation and welfare. The page aggregates peer-reviewed research articles and scholarly studies that explore the multifaceted relationships between humans and horses, examining both scientific and socio-economic perspectives.
Post-entry restriction of retroviral infections.
AIDS reviews    November 6, 2003   Volume 5, Issue 3 156-164 
Towers GJ, Goff SP.Pathogenic retroviruses have driven the evolution of several dominant-acting mechanisms able to block infection and protect the host. These are exemplified by the mouse gene Fv1, which encodes a Gag-like protein able to protect against murine leukemia virus (MLV) infection. The block is saturable, occurs after reverse transcription and is directed against the viral capsid gene. Several other mammalian species are also able to block MLV infection with the same capsid specificity. A human gene with this activity has been named Ref1. Recently, primates have been shown to restrict a variety of ret...
Preparation of equine isolated hepatocytes.
Toxicology in vitro : an international journal published in association with BIBRA    November 6, 2003   Volume 17, Issue 5-6 615-621 doi: 10.1016/s0887-2333(03)00112-7
Bakala A, Karlik W, Wiechetek M.In this study a detailed description of the equine hepatocyte isolation procedure is presented. Livers were obtained from horses slaughtered at the local slaughterhouse. For blood removal and liver preservation the following steps are suggested: perfusion with the oxygenated HBSS (0-2 degrees C, with continuous flow of 500-800 ml/min for 3-6 min), protection from ischemia injury by flushing with ice-cold University of Wisconsin Solution (UW, flow rate of 500-800 ml/min), and finally immersion of the liver lobe in UW solution (2 degrees C) during its transport to the laboratory. For equine isol...
Screening for West Nile virus infections of susceptible animal species in Austria.
Epidemiology and infection    November 5, 2003   Volume 131, Issue 2 1023-1027 doi: 10.1017/s0950268803001031
Weissenböck H, Hubálek Z, Halouzka J, Pichlmair A, Maderner A, Fragner K, Kolodziejek J, Loupal G, Kölbl S, Nowotny N.Avian mortality and encephalomyelitis in equines are considered good indicators for West Nile virus (WNV) activity. We retrospectively tested 385 horse sera for WNV antibodies and looked for WNV nucleic acid and/or WNV antigen in paraffin embedded tissues from 12 horses with aetiologically unresolved encephalomyelitis and 102 free-living birds of different species which had been found dead. With the exception of four horses originating from eastern European countries investigated on the occasion of transit through Austria, all horse sera were negative. Nested RT-PCR of the horse tissues yielde...
Epidemiology of leptospirosis: observations on serological data obtained by a “diagnostic laboratory for leptospirosis” from 1995 to 2001.
The new microbiologica    November 5, 2003   Volume 26, Issue 4 383-389 
Cerri D, Ebani VV, Fratini F, Pinzauti P, Andreani E.Serological data on leptospira infection were reported and discussed. From 1995 to 2001, the blood serum samples of 9885 domestic and wild animals and humans, living in Northern and Central Italy, were examined by the macroagglutination test (MAT) employing bratislava, ballum, canicola, grippotyphosa, icterohaemorrhagiae, pomona, hardjo and tarassovi serovars as antigens. Considering sera with > or = 1:400 antibody titers as positive, 674 (6.81%) animals scored positive. Sheep, horses, pigs and dogs gave the highest number of positive responses, particularly against the serovar bratislava and,...
Determination of reference range values indicative of glucose metabolism and insulin resistance by use of glucose clamp techniques in horses and ponies.
American journal of veterinary research    November 5, 2003   Volume 64, Issue 10 1260-1264 doi: 10.2460/ajvr.2003.64.1260
Rijnen KE, van der Kolk JH.To acquire reference range values indicative of glucose metabolism by use of the hyperglycemic clamp technique in healthy horses and evaluate the usefulness of the euglycemic hyperinsulinemic clamp technique in healthy horses and ponies. Methods: Dutch Warmblood horses and 4 Shetland ponies. Methods: The hyperglycemic clamp technique was used for quantification of the sensitivity of beta cells to exogenous glucose infusion in horses. The euglycemic hyperinsulinemic clamp technique was used to determine the sensitivity and responsiveness of tissues to exogenous insulin in horses and ponies. Res...
Equine passports.
The Veterinary record    October 31, 2003   Volume 153, Issue 15 475 
Ellis RN.No abstract available
West Nile virus activity–United States, October 23-29, 2003.
MMWR. Morbidity and mortality weekly report    October 31, 2003   Volume 52, Issue 43 1053-1054 
This report summarizes West Nile virus (WNV) surveillance data reported to CDC through ArboNET as of 3 a.m., Mountain Standard Time, October 29, 2003.
[Malignant melanoma of the pelvis as a possible cause of pelvic limb lameness in two gray mares].
Tijdschrift voor diergeneeskunde    October 30, 2003   Volume 128, Issue 17 512-518 
de Blaauw JA, Rijkenhuizen AB, van Nieuwstadt RA, Grinwis GC, Back W.Two grey mares, a 12-year-old Arabian and a 13-year-old Lippizaner cross, were referred for chronic pelvic limb lameness and abduction of the limb during the non supporting phase of the stride. The clinical examination revealed melanomas under the tail and on the perineum, and oedema of the proximal lame limb. A mass in the pelvic area was detected on rectal palpation. Laparoscopy was performed and the provisional diagnosis of malignant melanoma was made. Histological examination of the biopsy taken under laparoscopic control from the mass in the pelvis confirmed the diagnosis of malignant mel...
Intracapsular lens removal in a Przewalski’s wild horse (Equus caballus przewalskii).
Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians    October 30, 2003   Volume 34, Issue 3 284-286 doi: 10.1638/02-027
Kenny DE, Dugan SJ, Knightly F, Baier J.A 11.5-yr-old female Przewalski's wild horse (Equus caballus przewalskii) presented for unilateral blepharitis and drainage from the left eye. The left cornea was not ulcerated, and intraocular evaluation was hampered by severe corneal edema. The left eye appeared to respond positively to treatment with anti-inflammatories and a topical mydriatic agent. During the ensuing 2 yr, there were minor episodes of epiphora from the left eye. The discharge then increased, and a luxated lens was noted during an examination by a veterinary ophthalmologist as part of the preshipment examination. Initially...
Outbreak of equine herpesvirus type 1 myeloencephalitis: new insights from virus identification by PCR and the application of an EHV-1-specific antibody detection ELISA.
The Veterinary record    October 30, 2003   Volume 153, Issue 14 417-423 doi: 10.1136/vr.153.14.417
Studdert MJ, Hartley CA, Dynon K, Sandy JR, Slocombe RF, Charles JA, Milne ME, Clarke AF, El-Hage C.Five of 10 pregnant, lactating mares, each with a foal at foot, developed neurological disease. Three of them became recumbent, developed complications and were euthanased; of the two that survived, one aborted an equine herpesvirus type 1 (EHV-1)-positive fetus 68 days after the first signs were observed in the index case and the other gave birth to a healthy foal on day 283 but remained ataxic and incontinent. The diagnosis of EHV-1 myeloencephalitis was supported by postmortem findings, PCR identification of the virus and by serological tests with an EHV-1-specific ELISA. At the time of the...
Comparative pharmacokinetics of diphenhydramine in camels and horses after intravenous administration.
Veterinary research communications    October 30, 2003   Volume 27, Issue 6 463-473 doi: 10.1023/a:1025789607863
Wasfi IA, Abdel Hadi AA, Elghazali M, Alkateeri NA, Hussain MM, Hamid AM.The pharmacokinetics of diphenhydramine (DPHM) was compared in camels (n = 8) and horses (n = 6) following intravenous (i.v.) administration of a dose of 0.625 mg/kg body weight. In addition, the metabolism and urinary detection time of DPHM was evaluated in camels. The data obtained (median and range in brackets) in camels and horses, respectively, were as follows. The terminal elimination half lives (h) were 1.58 (1.13-2.58) and 6.11 (4.80-14.1), and the total body clearances (L/h per kg) were 1.42 (1.13-1.74) and 0.79 (0.66-0.90). The volumes of distribution at steady state (L/kg) were 2.38...
Diagnosis, treatment, and farriery for horses with chronic heel pain.
The Veterinary clinics of North America. Equine practice    October 25, 2003   Volume 19, Issue 2 417-441 doi: 10.1016/s0749-0739(03)00025-7
Dabareiner RM, Carter GK.In conclusion, horses with heel or navicular area pain vary, and no one treatment option is suitable for all horses. Each horse must be evaluated individually to determine which structure in the palmar aspect of the foot is injured, severity of disease, horse and hoof conformation, and horse use and level of performance expectation before a treatment plan can be developed. Overall, there are many treatment options to help these horses to perform their intended athletic event.
Hoof capsule distortion: understanding the mechanisms as a basis for rational management.
The Veterinary clinics of North America. Equine practice    October 25, 2003   Volume 19, Issue 2 443-462 doi: 10.1016/s0749-0739(03)00027-0
Redden RF.Understanding the basic mechanisms of hoof capsule distortion enables the clinician to unravel the sometimes complex mix of abnormalities, identify early warning signs, and manage existing problems more effectively. Distortion of the hoof capsule can often seem like a complicated puzzle by the time the veterinarian is called to examine the lame horse. Evaluating each of the components of the hoof capsule, both individually and as an integrated unit, allows the clinician to tease apart the tangle of primary and secondary problems and come up with effective options for countering or attenuating ...
Rabies DNA vaccine in the horse: strategies to improve serological responses.
Vaccine    October 25, 2003   Volume 21, Issue 31 4593-4596 doi: 10.1016/s0264-410x(03)00504-8
Fischer L, Minke J, Dufay N, Baudu P, Audonnet JC.In order for DNA vaccines to become a practical alternative to conventional vaccines their ability to induce antibody responses in large mammals needs to be improved. We used DNA vaccination against rabies in the horse as a model to test the potential of two different strategies to enhance antibody responses in a large mammalian species. The administration of the DNA vaccine in the presence of aluminum phosphate improved both the onset and the intensity of serological responses but was not potent enough to achieve seroconversion in all vaccinated ponies. However, when the DNA vaccine was formu...
Form and function of the equine digit.
The Veterinary clinics of North America. Equine practice    October 25, 2003   Volume 19, Issue 2 285-v doi: 10.1016/s0749-0739(03)00018-x
Parks A.The list of possible diagnoses derived from matching anatomic structures or tissues to pathologic processes is inevitably broad in nature. Understanding and observation of distal limb function, conformation, and balance is the basis of identifying where the greatest abnormal stresses within the distal limb are likely to occur. This is key to focusing the diagnostic process and, in some instances, to treating the horse when a definitive diagnosis cannot be achieved.
Foot management in the foal and weanling.
The Veterinary clinics of North America. Equine practice    October 25, 2003   Volume 19, Issue 2 501-517 doi: 10.1016/s0749-0739(03)00016-6
Greet TR, Curtis SJ.Foot management and hoof care of foals, weanlings, and yearlings tends to be considered a specialist job. Many farriers and veterinary surgeons have little exposure to young and growing stock. Nevertheless, a variety of angular and flexural limb deformities can benefit from simple podiatry techniques, which can be performed provided that a few basic rules are followed. The combined skills of the farrier and veterinary surgeon offer many young horses with angular or flexural limb deformities a chance of a future athletic career.
Chronic laminitis: current treatment strategies.
The Veterinary clinics of North America. Equine practice    October 25, 2003   Volume 19, Issue 2 393-vi doi: 10.1016/s0749-0739(03)00019-1
Parks A, O'Grady SE.Laminitis is divided into four different phases: developmental, acute, subacute, and chronic. The focus of this article is on treating the laminitic horse after the cessation of therapy for the acute phase, that is, usually 2 to 4 weeks after the onset of clinical signs.
Natural balance trimming and shoeing: its theory and application.
The Veterinary clinics of North America. Equine practice    October 25, 2003   Volume 19, Issue 2 353-vi doi: 10.1016/s0749-0739(03)00017-8
Ovnicek GD, Page BT, Trotter GW.The principles and techniques of natural balance trimming and shoeing are designed to optimize the efficiency and function of the foot. The basic guidelines have evolved in part from wild horse hoof imprint studies done in 1986 through 1987 and first presented in 1995. Further research has contributed to these principles and guidelines to make them applicable to domestic horses.
Radiographic imaging of the equine foot.
The Veterinary clinics of North America. Equine practice    October 25, 2003   Volume 19, Issue 2 379-vi doi: 10.1016/s0749-0739(03)00026-9
Redden RF.Radiographic examination of the equine foot can provide the veterinarian and farrier with a wealth of information. Positioning and selection of exposure factors are of central importance if one is to produce radiographs of maximum diagnostic value.
Hoof wall defects: chronic hoof wall separations and hoof wall cracks.
The Veterinary clinics of North America. Equine practice    October 25, 2003   Volume 19, Issue 2 463-477 doi: 10.1016/s0749-0739(03)00003-8
Moyer W.Hoof wall defects in horses are common occurrences, and, fortunately, many of those detected present little or no danger to the individual horse. Those defects that are either presently a problem or have a great likelihood of being a problem do often require specialized consideration. Horse shoeing and farriery are ancient practices; over the years, a multitude of methods, theories, and management schemes have been proposed. It is unfortunate to note that few studies are available to provide an accurate incidence rate, a better understanding of the various causes, and, lastly, a comparative ap...
Hoof wall surgery in the horse: approaches to and underlying disorders.
The Veterinary clinics of North America. Equine practice    October 25, 2003   Volume 19, Issue 2 479-499 doi: 10.1016/s0749-0739(03)00002-6
Honnas CM, Dabareiner RM, McCauley BH.Because of the hoof capsule, surgery of the equine foot is often perceived to be quite difficult. Knowledge of the specific disease entities that require surgical intervention as well as an in-depth understanding of the anatomy of the tissues beneath the hoof capsule is a definite prerequisite to successful surgical treatment. This article details the surgical approaches used to treat septic navicular bursitis, septic pedal osteitis, infection of the collateral cartilages, and keratomas. The principles used to treat these conditions can be applied to a variety of other conditions for which acc...
The role and importance of farriery in equine veterinary practice.
The Veterinary clinics of North America. Equine practice    October 25, 2003   Volume 19, Issue 2 273-283 doi: 10.1016/s0749-0739(03)00022-1
Merriam JG.There is a lot of room for us to become the central source of medical information regarding shoeing and lameness in our own practice area. This takes a good bit of effort and a real "outreach" to client and farrier. It can be done with the one tool we are best at--the acquisition and careful dispensing of information that we can put together regarding the health of the foot. Such information includes the following: 1. Radiographically guided hoof trimming and shoeing. 2. Ultrasonography. 3. Digital radiography. 4. Thermography. 5. Nutritional and health counseling. Become the "local" expert in...
Examination of the equine foot.
The Veterinary clinics of North America. Equine practice    October 25, 2003   Volume 19, Issue 2 309-332 doi: 10.1016/s0749-0739(03)00023-3
Turner TA.The examination of the foot must be based on observations of the hoof, followed by a careful determination of areas of pain. This must be followed by an assessment of the biomechanical forces on the hoof and limb. Finally, imaging gives insight into the nature of the injury and allows the examiner to prognosticate the outcome.
Rhodococcus equi secreted antigens are immunogenic and stimulate a type 1 recall response in the lungs of horses immune to R. equi infection.
Infection and immunity    October 24, 2003   Volume 71, Issue 11 6329-6337 doi: 10.1128/IAI.71.11.6329-6337.2003
Kohler AK, Stone DM, Hines MT, Byrne BA, Alperin DC, Norton LK, Hines SA.Rhodococcus equi is an opportunistic pathogen in immunocompromised humans and an important primary pathogen in young horses. Although R. equi infection can produce life-threatening pyogranulomatous pneumonia, most foals develop a protective immune response that lasts throughout life. The antigen targets of this protective response are currently unknown; however, Mycobacterium tuberculosis is a closely related intracellular pathogen and provides a model system. Based on previous studies of M. tuberculosis protective antigens released into culture filtrate supernatant (CFS), a bacterial growth s...
Long-term follow-up of manipulative treatment in a horse with back problems.
Journal of veterinary medicine. A, Physiology, pathology, clinical medicine    October 22, 2003   Volume 50, Issue 5 241-245 doi: 10.1046/j.1439-0442.2003.00527.x
Faber MJ, van Weeren PR, Schepers M, Barneveld A.In order to objectively quantify the effect of manipulation on back-related locomotion anomalies in the horse, a recently developed kinematic measuring technique for the objective quantification of thoracolumbar motion in the horse was applied in a dressage horse that was suffering from a back problem. In this horse, clinically, a right-convex bending (scoliosis) from the 10th thoracic vertebra to the second lumbar vertebra was diagnosed. As a result, there was a marked asymmetric movement of the thoracolumbar spine. Functionally, there was severe loss of performance. Thoracolumbar motion was ...
Comparison of perioperative versus postoperative intratumoral administration of cisplatin for treatment of cutaneous sarcoids and squamous cell carcinomas in horses.
Journal of the American Veterinary Medical Association    October 22, 2003   Volume 215, Issue 11 1655-1660 
Théon AP, Pascoe JR, Galuppo LD, Fisher PE, Griffey SM, Madigan JE.To determine the benefits of reducing the interval between surgical cytoreduction and intratumoral administration of cisplatin. Methods: Randomized clinical study. Methods: 70 horses with 89 incompletely resected T2- and T3-stage sarcoids (n = 64) and squamous cell carcinomas (25). Methods: Horses were given 4 intratumoral treatments of cisplatin at 2-week intervals. The first treatment was given at the time of, or immediately after, surgical resection for horses treated in accordance with the perioperative protocol (group 1). Horses in group 2 were treated with cisplatin after the skin healed...
Empyema of the guttural pouch (auditory tube diverticulum) in horses: 91 cases (1977-1997).
Journal of the American Veterinary Medical Association    October 22, 2003   Volume 215, Issue 11 1666-1670 
Judy CE, Chaffin MK, Cohen ND.To identify features of guttural pouch (auditory tube diverticulum) empyema in horses and compare findings of uncomplicated guttural pouch empyema with guttural pouch empyema complicated by chondroids. Methods: Retrospective study. Methods: 91 horses with guttural pouch empyema. Methods: Medical records of horses with guttural pouch empyema were reviewed. Results: The most common owner complaint and abnormal finding was persistent nasal discharge. Chondroids were detected in 21% (19/91) of affected horses. Streptococcus equi was isolated from the guttural pouch in 14 of 44 horses; for Streptoc...
Clinical and pathologic findings in two draft horses with progressive muscle atrophy, neuromuscular weakness, and abnormal gait characteristic of shivers syndrome.
Journal of the American Veterinary Medical Association    October 22, 2003   Volume 215, Issue 11 1661-1621 
Valentine BA, de Lahunta A, Divers TJ, Ducharme NG, Orcutt RS.Two Belgian geldings, 4 and 14 years old, respectively, with muscle atrophy, weakness, and abnormal gait characteristic of severe advanced shivers were examined clinically and on necropsy. Neurologic examination revealed no evidence of ataxia, and the clinical diagnosis was neuromuscular weakness and shivers. Necropsies of both horses, including examination of pituitary, brain, spinal cord, spinal roots and ganglia, and peripheral nerves, revealed no gross or histologic abnormalities. Examination of multiple skeletal muscle specimens revealed chronic myopathic changes and periodic acid-Schiff ...
Usefulness of aerobic microbial culture and cytologic evaluation of corneal specimens in the diagnosis of infectious ulcerative keratitis in animals.
Journal of the American Veterinary Medical Association    October 22, 2003   Volume 215, Issue 11 1671-1674 
Massa KL, Murphy CJ, Hartmann FA, Miller PE, Korsower CS, Young KM.To determine the diagnostic value of aerobic microbial culture and cytologic evaluation of corneal specimens in the diagnosis of infectious ulcerative keratitis (IUK). Methods: Prospective study. Methods: 48 animals (26 dogs, 13 horses, 7 cats, 1 bird, and 1 llama) with corneal ulcers. Methods: Scrapings from corneal ulcers were examined cytologically. Corneal swab specimens were submitted for microbial culture. Animals were grouped according to whether they had been receiving antimicrobials at the time of admission. Results: Of the 38 animals receiving antimicrobials, 19 had positive results ...
Horses added to the list of cloned species.
Reproductive biomedicine online    October 22, 2003   Volume 7, Issue 2 138 
No abstract available