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Topic:Joint Health

Joint health in horses involves the study of anatomical structures such as cartilage, synovial fluid, ligaments, and bones that contribute to the function and mobility of equine joints. Research in this area focuses on understanding the physiology of equine joints, the mechanisms of joint disorders, and the effects of wear and tear over time. Common joint issues in horses include osteoarthritis, synovitis, and joint effusion, which can impact performance and quality of life. Diagnostic techniques often involve imaging, synovial fluid analysis, and clinical evaluation to assess joint condition. This page compiles peer-reviewed research studies and scholarly articles that explore the anatomy, pathology, diagnostics, and therapeutic approaches related to joint health in horses.
Use of a three-drill-tract technique for arthrodesis of the distal tarsal joints in horses with distal tarsal osteoarthritis: 54 cases (1990-1999).
Journal of the American Veterinary Medical Association    December 24, 2003   Volume 223, Issue 12 1800-1805 doi: 10.2460/javma.2003.223.1800
Dechant JE, Baxter GM, Southwood LL, Crawford WH, Jackman BR, Stashak TS, Trotter GW, Hendrickson DA.To assess the long-term clinical outcome of horses with distal tarsal osteoarthritis (OA) in which a 3-drill-tract technique was used to induce arthrodesis of the affected joints, identify any preoperative or operative factors associated with outcome, and describe any complications associated with the technique. Methods: Retrospective study. Methods: 54 horses. Methods: Medical records were reviewed for information on signalment, use, history, physical and lameness examination findings, surgical technique, and postoperative care. Radiographs were examined, and severity of OA was graded. Follow...
Effect of induced unilateral synovitis of distal intertarsal and tarsometatarsal joints on sagittal plane kinematics and kinetics of trotting horses.
American journal of veterinary research    December 16, 2003   Volume 64, Issue 12 1491-1495 doi: 10.2460/ajvr.2003.64.1491
Khumsap S, Lanovaz JL, Rosenstein DS, Byron C, Clayton HM.To study the effect of unilateral synovitis in the distal intertarsal and tarsometatarsal joints on locomotion, including the compensating effects within and between limbs. Methods: 4 clinically normal horses. Methods: Gait analyses including kinematics, force plate, and inverse dynamic analysis were performed at the trot before lameness, after which synovitis was induced by injecting endotoxin into the right distal intertarsal and tarsometatarsal joints. Gait analyses were repeated 24 to 30 hours later during lameness. Differences between the stride variables during the 2 conditions (lame and...
Quantification and age-related distribution of articular cartilage degeneration in the equine fetlock joint.
Equine veterinary journal    December 3, 2003   Volume 35, Issue 7 697-701 doi: 10.2746/042516403775696357
Brommer H, van Weeren PR, Brama PA, Barneveld A.The equine fetlock joint has the largest number of traumatic and degenerative lesions of all joints of the appendicular skeleton. Objective: To gain insight into the distribution of cartilage degeneration across the articular surface in relation to age in order better to understand the dynamic nature and progression of osteoarthritis (OA). Objective: That there would be a specific age-related distribution pattern of cartilage degeneration in the equine metacarpophalangeal joint. Methods: The proximal articular cartilage surfaces of the first phalanges (P1) of 73 slaughter horses (age range 0.4...
Scapulohumeral arthrodesis in miniature horses.
Veterinary surgery : VS    October 22, 2003   Volume 32, Issue 5 416-420 doi: 10.1053/jvet.2003.50053
Semevolos SA, Watkins JP, Auer JA.To describe surgical arthrodesis of the scapulohumeral joint and to evaluate its efficacy in reducing morbidity associated with severe shoulder dysfunction in miniature horses. Methods: Retrospective study. Methods: Four miniature horses. Methods: Medical records and radiographs were reviewed for history, physical examination findings, lameness evaluation, radiographic evaluation, surgical techniques, postoperative complications, and outcome. A 10- or 11-hole, 4.5-mm narrow dynamic compression plate and 4.5-mm cortical screws were applied to the cranial surface of the scapula and cranial surfa...
Arthroscopy in the horse.
Veterinary research communications    October 11, 2003   Volume 27 Suppl 1 79-83 doi: 10.1023/b:verc.0000014122.81514.88
Muttini A, Vantini C, Cuomo A.No abstract available
A preliminary evaluation of the use of equine neutrophil elastase 2A concentration in synovial fluid as a marker for joint inflammation in horses.
Equine veterinary journal    October 1, 2003   Volume 35, Issue 6 623-626 doi: 10.2746/042516403775467306
Dagleish MP, Wakeman KD, McDiarmid AM.No abstract available
Endoscopic surgery in the treatment of contaminated and infected synovial cavities.
Equine veterinary journal    October 1, 2003   Volume 35, Issue 6 613-619 doi: 10.2746/042516403775467225
Wright IM, Smith MR, Humphrey DJ, Eaton-Evans TC, Hillyer MH.Contamination and infection of synovial cavities are a common occurrence in clinical practice and, if inadequately treated, may have career or life threatening consequences for affected horses. Objective: The objectives in treating contamination and infection of joints, tendon sheaths and bursae are most effectively met by endoscopic surgery. Methods: Over a 6 year period, cases of synovial contamination and infection admitted to a referral clinic were evaluated and treated endoscopically. The horses received local and systemic antimicrobial drugs with minimal nonsteroidal anti-inflammatory me...
Meniscal tears in horses: an evaluation of clinical signs and arthroscopic treatment of 80 cases.
Equine veterinary journal    July 26, 2003   Volume 35, Issue 4 402-406 doi: 10.2746/042516403776014163
Walmsley JR, Phillips TJ, Townsend HG.There is little published information available describing clinical signs, arthroscopic findings and prognosis of meniscal injuries in horses. Objective: To evaluate the effect on the outcome not only of the arthroscopic findings and treatment, but also of the clinical and radiographic signs in these horses. Methods: The following were recorded for each case: the meniscal injury, graded according to severity; clinical and radiographic findings prior to surgery; any concurrent injury in the joint seen at arthroscopy. The effect of these factors and the grade of injury on the outcome were analys...
The effects of local anaesthetic solution in the navicular bursa of horses with lameness caused by distal interphalangeal joint pain.
Equine veterinary journal    July 24, 2003   Volume 35, Issue 5 502-505 doi: 10.2746/042516403775600460
Schumacher J, Schumacher J, Gillette R, DeGraves F, Schramme M, Smith R, Perkins J, Coker M.Analgesia of the palmar digital (PD) nerves has been demonstrated to cause analgesia of the distal interphalangeal (DIP) joint as well as the sole. Because the PD nerves lie in close proximity to the navicular bursa, we suspected that that analgesia of the navicular bursa would anaesthetise the PD nerves, which would result in analgesia of the DIP joint. Objective: To determine the response of horses with pain in the DIP joint to instillation of local anaesthetic solution into the navicular bursa. Methods: Lameness was induced in 6 horses by creating painful synovitis in the DIP joint of one f...
Articular chondrocyte apoptosis in equine osteoarthritis.
Veterinary journal (London, England : 1997)    June 6, 2003   Volume 166, Issue 1 52-57 doi: 10.1016/s1090-0233(02)00305-2
Kim DY, Taylor HW, Moore RM, Paulsen DB, Cho DY.Osteoarthritis (OA) is the most common joint disease in horses. Chondrocyte apoptosis has been implicated as a major pathological OA change in humans and experimental animals but no studies have been performed on equine OA. Articular cartilage was collected from three normal and five OA horses. Histopathological changes were scored by a modified Mankin grading system. A terminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling (TUNEL) assay was performed to identify chondrocyte apoptosis. Nitric oxide (NO) production from chondrocytes was indirectly evaluated by immunohistochemistr...
Cylindrical press-fit osteochondral allografts for resurfacing the equine metatarsophalangeal joint.
Veterinary surgery : VS    June 5, 2003   Volume 32, Issue 3 220-230 doi: 10.1053/jvet.2003.50032
Pearce SG, Hurtig MB, Boure LP, Radcliffe RM, Richardson DW.To investigate the feasibility of resurfacing the equine fetlock joint using cylindrical, orthotopic, press-fit, osteochondral allografts. Methods: Experimental study. Methods: Ten mature, mixed-breed horses. Methods: Cylindrical, osteochondral grafts (6.5-mm diameter) were harvested aseptically from cadaveric equine metatarsophalangeal joints. Allografts were transplanted into 6 horses; 4 horses were sham operated. The surgical approach involved creation of a bone block at the origin of the medial collateral ligament and luxation of the metatarsophalangeal joint. Grafts were placed into the m...
The sacroiliac joints: evaluation using nuclear scintigraphy. Part 2: Lame horses.
Equine veterinary journal    May 21, 2003   Volume 35, Issue 3 233-239 doi: 10.2746/042516403776148282
Dyson S, Murray R, Branch M, Harding E.Sacroiliac (SI) joint disease is difficult to diagnose definitively on clinical grounds. Objective: Lameness not attributable to SI joint pain may result in asymmetrical uptake of radiopharmaceutical in the tubera sacrale and SI joints; and that horses with clinical signs suggestive of sacroiliac joint disease would have differences in the ratios of radiopharmaceutical uptake between the fifth lumbar vertebra (L5) and either the tubera sacrale or SI joints compared with normal horses. Objective: To determine whether differences in radiopharmaceutical activity could identify individuals with pr...
The sacroiliac joints: evaluation using nuclear scintigraphy. Part 1: The normal horse.
Equine veterinary journal    May 21, 2003   Volume 35, Issue 3 226-232 doi: 10.2746/042516403776148219
Dyson S, Murray R, Branch M, Whitton C, Donovan T, Harding E.Sacroiliac (SI) disease is recognised as a cause of poor hindlimb action but differential diagnosis is often difficult. Objective: That in clinically normal horses there would be a significant difference in the ratio of radiopharmaceutical uptake (RU) between the fifth lumbar vertebra (L5) and each tuber sacrale (TS) and between L5 and each SI joint; and that these ratios would alter with age, but ratios would be bilaterally symmetrical. Methods: Dorsal scintigraphic images of the SI region of 15 horses, selected randomly from the clinic database, were analysed by 2 of the authors, comparing n...
Pain associated with the sacroiliac joint region: a clinical study of 74 horses.
Equine veterinary journal    May 21, 2003   Volume 35, Issue 3 240-245 doi: 10.2746/042516403776148255
Dyson S, Murray R.There has been no large study of horses with suspected sacroiliac (SI) joint region pain in which the clinical diagnosis has been supported by either abnormal radiopharmaceutical activity in the SI joint region or by periarticular infiltration of local anaesthetic solution. Objective: To describe the clinical features of horses with SI joint region pain, to document the age, breed, sex, discipline, size and conformation of affected horses and to compare these with the author's (SD) normal case population and to document the results of infiltration of local anaesthetic solution around the SI jo...
Effect of foot balance on the intra-articular pressure in the distal interphalangeal joint in vitro.
Equine veterinary journal    March 18, 2003   Volume 35, Issue 2 184-189 doi: 10.2746/042516403776114199
Viitanen MJ, Wilson AM, McGuigan HR, Rogers KD, May SA.Increased joint pressure has been implicated in the progression of osteoarthritis. Objective: That intra-articular pressure in the distal interphalangeal joint (DIP) is significantly higher in legs loaded with heel up (HU), low heel (TU), lateral side up (LU) and medial side up (MU) imbalance compared to the balanced position. Methods: Twelve elbow down limbs were compressed in a hydraulic loading jig and DIP pressure measured. Results: Elevating the heels by 5 degrees significantly increased DIP pressure. After 5 ml of contrast was injected into the joint, heel elevation caused a greater incr...
New approach for quantitative assessment of articular cartilage degeneration in horses with osteoarthritis.
American journal of veterinary research    January 10, 2003   Volume 64, Issue 1 83-87 doi: 10.2460/ajvr.2003.64.83
Brommer H, van Weeren PR, Brama PA.To evaluate a modified digital imaging technique for quantitative assessment of the grade of osteoarthritis across the proximal articular surface of the first phalanx in horses. Methods: 6 metacarpophalangeal (fet-lock) joint specimens from 6 horses with various stages of osteoarthritis. Methods: First phalanx specimens, together with 4 gray scale reference calibration targets, were positioned in a bath with the proximal articular cartilage surface submerged in saline (0.9% NaCl) solution. Digital images were obtained from the articular surface before and after staining with Indian ink. Comput...
Plasma and synovial fluid endothelin-1 and nitric oxide concentrations in horses with and without joint disease.
American journal of veterinary research    December 21, 2002   Volume 63, Issue 12 1648-1654 doi: 10.2460/ajvr.2002.63.1648
de la Calle J, Burba DJ, Ramaswamy CM, Hosgood G, Williams J, LeBlanc C, Moore RM.To compare plasma and synovial fluid endothelin-1 (ET-1) and nitric oxide (NO) concentrations in clinically normal horses and horses with joint disease. Methods: 36 horses with joint disease, and 15 horses without joint disease. Methods: Horses with joint disease were assigned to 1 of the 3 groups (ie, synovitis, degenerative joint disease [DJD], or joint sepsis groups) on the basis of findings on clinical and radiographic examination and synovial fluid analysis. Endothelin-1 and NO concentrations were measured in plasma from blood samples, collected from the jugular vein and ipsilateral cepha...
Effects of analgesia of the distal interphalangeal joint and navicular bursa on experimental lameness caused by solar pain in horses.
Journal of veterinary medicine. A, Physiology, pathology, clinical medicine    December 20, 2002   Volume 49, Issue 9 478-481 doi: 10.1046/j.1439-0442.2002.00482.x
Sardari K, Kazemi H, Mohri M.It has been hypothesized that pain originating from the dorsal margin of the sole of the hoof in horses can be attenuated by analgesia of either the distal interphalangeal (DIP) joint, or of the navicular bursa (NB). To test this hypothesis, an experimental lameness was induced in the toe region of the left forelimb in six adult horses. After this, both synovial structures were blocked and the effects on the lameness were semi-quantitatively scored. Lameness was induced by creating pressure on the dorsal margin of the sole with the help of set-screws that were screwed into a nut, welded to the...
Evaluation of a cranial arthroscopic approach to the stifle joint for the treatment of femorotibial joint disease in horses: 23 cases (1998-1999).
Journal of the American Veterinary Medical Association    November 8, 2002   Volume 220, Issue 7 1046-1052 doi: 10.2460/javma.2002.220.1046
Peroni JF, Stick JA.To describe a single-portal cranial arthroscopic approach to the stifle joint in horses and to determine the clinical outcome in horses with femorotibial joint disease in which this approach was used. Methods: Retrospective study. Methods: 23 adult horses. Methods: Medical records were reviewed to obtain information on clinical outcome in horses in which the single-portal cranial arthroscopic approach was used. Results: Twenty-nine stifle joints of 23 horses were examined arthroscopically, using the described approach. Subchondral bone cysts were treated in 19 medial femoral condyles of 12 hor...
Inhibition of articular cartilage degradation by glucosamine-HCl and chondroitin sulphate.
Equine veterinary journal. Supplement    October 31, 2002   Issue 34 224-229 doi: 10.1111/j.2042-3306.2002.tb05423.x
Orth MW, Peters TL, Hawkins JN.Glucosamine and chondroitin sulphate in many animal and human trials has improved joint health. In vitro studies are beginning to clarify their mode of action. The objective of this research was to: 1) determine at what concentrations glucosamine-HCl (GLN) and/or chondroitin sulphate (CS) would inhibit the cytokine-induced catabolic response in equine articular cartilage explants and 2) to determine if a combination of the 2 was more effective at inhibiting the catabolic response than the individual compounds. Articular cartilage was obtained from carpal joints of horses (age 1-4 years). Carti...
Serum level of cartilage oligomeric matrix protein (COMP) in equine osteoarthritis.
Equine veterinary journal    October 3, 2002   Volume 34, Issue 6 602-608 doi: 10.2746/042516402776180205
Misumi K, Vilim V, Hatazoe T, Murata T, Fujiki M, Oka T, Sakamoto H, Carter SD.This study was designed to assay and compare cartilage oligomeric matrix protein (COMP) in horse sera, in samples from normal and joint diseased horses, and to investigate the relationships between COMP in sera and synovial fluids (SF) with keratan sulphate (KS) data. Sera from 38 horses free of any joint pathology (controls) and from horses with aseptic joint disease (AJD horses, n = 40) were assayed for COMP and KS concentrations. Of the 78 horses in the study, 53 were also assayed for COMP and KS concentrations in SF. COMP and KS were measured by inhibition ELISA, using monoclonal antibodie...
Subluxation of the left elbow joint in a pony at induction of general anaesthesia.
The Veterinary record    August 31, 2002   Volume 151, Issue 6 183-184 doi: 10.1136/vr.151.6.183
Senior M, Smith M, Clegg P.No abstract available
Three-dimensional kinematics of the equine interphalangeal joints: articular impact of asymmetric bearing.
Veterinary research    August 30, 2002   Volume 33, Issue 4 371-382 doi: 10.1051/vetres:2002023
Chateau H, Degueurce C, Jerbi H, Crevier-Denoix N, Pourcelot P, Audigié F, Pasqui-Boutard V, Denoix JM.The objective of this study was to assess the effects of asymmetric placement of the foot on the three-dimensional motions of the interphalangeal joints. Four isolated forelimbs were used. Trihedrons, made of three axes fitted with reflective markers, were screwed into each phalanx. They allowed to establish a local frame associated with each bone and thus to define the spatial orientation of the phalanges. The limbs were then placed under a power press, and subjected to compression with gradually increasing force (from 500 to 6 000 N). The procedure was performed in neutral position and with ...
[Direct endoscopic approach improves prognosis of septic-synovitis in the horse].
Tijdschrift voor diergeneeskunde    August 17, 2002   Volume 127, Issue 14-15 444-449 
ter Braake F.The medical records of 71 horses with sepic arthritis, bursitis, or tenosynovitis, treated between 1996 and 2001 at Dierenkliniek Enmeloord, were reviewed. A total number of 81 joints, tendon sheaths and bursae were treated (21 tarsi, 17 digital tendon sheaths, 14 metacarpo/metatarso-phalangeal joints, 12 stifles, 6 carpi, 4 coffin joints, 2 navicular bursae, 1 elbow joint, 1 proximal-interphalangeal joint, 1 tarsal sheath, 1 bursa calcanei subtendineum). The aetiology in 42 cases was a penetrating wound (group 1), in 4 cases an intra-articular injection, and in 2 cases arthroscopic surgery (g...
ATPase and Adpase activities in synovial membrane of equine metacarpophalangeal joint.
Life sciences    August 2, 2002   Volume 70, Issue 20 2445-2455 doi: 10.1016/s0024-3205(02)01529-1
Jiménez PA, García L, Adarmes H, González E, Valenzuela MA.ATPase and ADPase activities capable of hydrolyzing nucleoside di- and triphosphates in the presence of Ca2+ are present in synovial membrane of metacarpophalangeal joint mainly associated to membrane fractions. These hydrolytic activities have been considered involved in the inflammatory process where ATP and ADP are inflammatory mediators while adenosine counteracts this effect. Both, subcellular localization and kinetic properties of these nucleotidase activities, suggest that could correspond to single enzyme called ATP-diphosphohydrolase or apyrase. The comparison of the activity on ATP-C...
The arthroscopic approach and intra-articular anatomy of the equine temporomandibular joint.
Equine veterinary journal    July 16, 2002   Volume 34, Issue 4 421-424 doi: 10.2746/042516402776249155
Weller R, Maierl J, Bowen IM, May SA, Liebich HG.No abstract available
Synovial regeneration in the equine carpus after arthroscopic mechanical or carbon dioxide laser synovectomy.
Veterinary surgery : VS    July 3, 2002   Volume 31, Issue 4 331-343 doi: 10.1053/jvet.2002.33605
Doyle-Jones PS, Sullins KE, Saunders GK.To compare synovial regeneration in the equine carpus after mechanical or CO(2) laser synovectomy. Methods: Arthroscopic partial synovectomy was performed in the radiocarpal and intercarpal joints. Methods: Twelve horses, 3 to 6 years of age, were randomly divided into 3 groups. Methods: The antebrachiocarpal and intercarpal joints in each horse were randomly assigned a treatment such that each horse had one joint treated as a control (arthroscopic lavage), one in which a mechanical or CO(2) laser partial dorsal carpal synovectomy was performed, and one in which a combination of the mechanical...
The influence of exercise on the composition of developing equine joints.
Biorheology    June 26, 2002   Volume 39, Issue 1-2 183-191 
van de Lest CH, Brama PA, Van Weeren PR.An overview is given of the direct and long-term effects of exercise on the biochemical characteristics of cartilage and subchondral bone, and on the metabolic activity of chondrocytes in the juvenile horse. In the experimental setup 43 foals were reared until weaning at 5 months of age under similar conditions, except for the type and amount of exercise. Fifteen foals remained at pasture (Pasture group and also control group), 14 foals were kept in box stalls (Box group), and 14 foals were kept in the same box stalls but were subjected daily to an increasing number of gallop sprints (Training...
Serum keratan sulphate as a cartilage metabolic marker in horses: the effect of exercise.
Journal of veterinary medicine. A, Physiology, pathology, clinical medicine    June 19, 2002   Volume 49, Issue 4 195-197 doi: 10.1046/j.1439-0442.2002.00434.x
Okumura M, Kim GH, Tagami M, Haramaki S, Fujinaga T.Keratan sulphate (KS) concentration in sera from resting horses and horses training daily on a racetrack was measured by an inhibition enzyme-linked immunosorbent assay (ELISA) using anti-equine KS antibody 1/14/16H9. For the in-training horses, serum KS concentrations in 2-year-old-horses was significantly higher than 3- or 4-year-old-horses. A higher concentration of serum KS was found in the in-training group than in the long-term resting group in 2-year-old-horses. Serum KS concentration increased remarkably immediately after training in healthy horses, and at 1, 5, 9 and 24 h after traini...
The role of complementary techniques in managing musculoskeletal pain in performance horses.
The Veterinary clinics of North America. Equine practice    June 18, 2002   Volume 18, Issue 1 107-vii doi: 10.1016/s0749-0739(01)00005-0
Wolf L.The locomotor system requires normal movement for normal function. Movement restrictions of soft tissues and joints stimulate nociceptive pathways in the corresponding vertebral segment. Reflex-induced alterations of sensory and motor neuron activity within the segment lead to detrimental changes within many of the tissues associated with and distant from the area. Manual therapy is utilized in both diagnosis and treatment of tissue and joint movement restrictions. Early recognition and treatment of dysfunction in the equine athlete prevents permanent pathology and facilitates performance exce...
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