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Topic:Musculoskeletal System

The musculoskeletal system in horses encompasses the bones, muscles, tendons, ligaments, and joints that facilitate movement and provide structural support. This system is essential for locomotion, athletic performance, and overall health in equine species. The equine skeleton consists of approximately 205 bones, which are connected by joints and supported by a network of muscles and connective tissues. Tendons connect muscles to bones, while ligaments link bones to other bones, contributing to joint stability. The musculoskeletal system is subject to various conditions, including injuries, degenerative diseases, and developmental disorders, which can impact a horse's mobility and performance. This page compiles peer-reviewed research studies and scholarly articles that explore the anatomy, physiology, pathology, and treatment of musculoskeletal conditions in horses.
Compressive fatigue life of subchondral bone of the metacarpal condyle in thoroughbred racehorses.
Bone    September 21, 2013   Volume 57, Issue 2 392-398 doi: 10.1016/j.bone.2013.09.006
Martig S, Lee PV, Anderson GA, Whitton RC.In racehorses, fatigue related subchondral bone injury leads to overt fracture or articular surface collapse and subsequent articular cartilage degeneration. We hypothesised that the fatigue behaviour of equine subchondral bone in compression follows a power law function similar to that observed in cortical and trabecular bone. We determined the fatigue life of equine metacarpal subchondral bone in-vitro and investigated the factors influencing initial bone stiffness. Subchondral bone specimens were loaded cyclically in compression [54MPa (n=6), 66MPa (n=6), 78MPa (n=5), and 90MPa (n=6)] until...
Effect of different kinds of anoxia/reoxygenation on the mitochondrial function and the free radicals production of cultured primary equine skeletal myoblasts.
Research in veterinary science    September 18, 2013   Volume 95, Issue 3 870-878 doi: 10.1016/j.rvsc.2013.09.004
Ceusters JD, Mouithys-Mickalad AA, Franck TJ, Deby-Dupont GP, Derochette S, Serteyn DA.Horses are outstanding athletes, performing in many different disciplines involving different kinds of efforts and metabolic responses. Depending on exercise intensity, their skeletal muscle oxygenation decreases, and the reperfusion at cessation of the exercise can cause excessive production of free radicals. This study on cultured primary equine myoblasts investigated the effect of different kinds of anoxia/reoxygenation (A/R) on routine respiration, mitochondrial complex I specific activity and free radicals production. Our data revealed that short cycles of A/R caused a decrease of all the...
Elastographic characteristics of the metacarpal tendons in horses without clinical evidence of tendon injury. Lustgarten M, Redding WR, Labens R, Morgan M, Davis W, Seiler GS.Tendon and ligament injuries are common causes of impaired performance in equine athletes. Gray-scale ultrasonography is the current standard method for diagnosing and monitoring these injuries, however this modality only provides morphologic information. Elastography is an ultrasound technique that allows detection and measurement of tissue strain, and may provide valuable mechanical information about equine tendon and ligament injuries. The purpose of this study was to determine the feasibility, reproducibility, and repeatability of elastography; and to describe elastographic characteristics...
Accuracy of low-field magnetic resonance imaging versus radiography for guiding injection of equine distal interphalangeal joint collateral ligaments. Lamb MM, Barrett JG, White NA, Werre SR.Desmopathy of the distal interphalangeal joint collateral ligament is a common cause of lameness in the horse and carries a variable prognosis for soundness. Intralesional treatment has been proposed for improving outcome; however, limited reports describe methods for injecting this ligament. The purpose of this study was to compare accuracy of low-field magnetic resonance imaging (MRI) vs. radiography for injecting the collateral ligament of the distal interphalangeal joint. Equine cadaver digit pairs (n = 10) were divided by random assignment to injection of the ligament by either technique....
Constraints on Mammalian forelimb development: insights from developmental disparity.
Evolution; international journal of organic evolution    September 12, 2013   Volume 67, Issue 12 3645-3652 doi: 10.1111/evo.12204
Ross D, Marcot JD, Betteridge KJ, Nascone-Yoder N, Bailey CS, Sears KE.Tetrapod limb development has been studied extensively for decades, yet the strength and role of developmental constraints in this process remains unresolved. Mammals exhibit a particularly wide array of limb morphologies associated with various locomotion modes and behaviors, providing a useful system for identifying periods of developmental constraint and conserved developmental mechanisms or morphologies. In this study, landmark-based geometric morphometrics are used to investigate levels and patterns of morphological diversity (disparity) among the developing forelimbs of four mammals with...
Musculoskeletal injury rates in Thoroughbred racehorses following local corticosteroid injection.
Veterinary journal (London, England : 1997)    September 12, 2013   Volume 200, Issue 1 71-76 doi: 10.1016/j.tvjl.2013.09.003
Whitton RC, Jackson MA, Campbell AJ, Anderson GA, Parkin TD, Morton JM, Boden LA.A retrospective cohort study was performed to compare the rates of musculoskeletal injury (MSI) in horses receiving local corticosteroid injection (LCI) with those that were untreated and those prior to treatment. Of the 1911 study horses, 392 had been treated. A LCI was defined as any injection of corticosteroid into or adjacent to a synovial structure, muscle, or tendon/ligament. A MSI was defined as any limb injury identified by a veterinarian, following which the horse did not race for at least 6 months, or was retired. Hazard ratios (HR) comparing hazard of injury following injection to t...
Area of cartilage accessible to curettage for subsequent arthrodesis of the equine proximal interphalangeal joint. Comparison of conventional and collateral ligament sparing approaches.
Veterinary and comparative orthopaedics and traumatology : V.C.O.T    September 6, 2013   Volume 26, Issue 6 489-492 doi: 10.3415/VCOT-12-01-0016
Kuemmerle JM, Berchtold S.This study compared the areas of cartilage accessible for curettage in arthrodesis of the equine proximal interphalangeal joint using the conventional and collateral ligament sparing approaches. For this purpose, forelimbs and hindlimbs of six equine cadavers without radiographic evidence of proximal interphalangeal joint disease were used. One limb of each pair of limbs was randomly assigned to a dissection using a standard approach to the proximal interphalangeal joint including transection of the collateral ligaments, while each contralateral limb was exposed using the same approach but lea...
Distal hindlimb kinematics of galloping Thoroughbred racehorses on dirt and synthetic racetrack surfaces.
Equine veterinary journal    August 30, 2013   Volume 46, Issue 2 227-232 doi: 10.1111/evj.12113
Symons JE, Garcia TC, Stover SM.The effect of racetrack surface (dirt or synthetic) on distal hindlimb kinematics of racehorses running at competition speeds is not known. Objective: To compare distal hindlimb and hoof kinematics during stance of breezing (unrestrained gallop) racehorses between dirt and synthetic surfaces. Methods: Two-dimensional kinematic video analysis of 5 Thoroughbred racehorses galloping at high speeds (12-17 m/s) on a dirt racetrack and a synthetic racetrack. Methods: The positions of kinematic markers applied to the left hindlimb were recorded at 500 Hz. Position, velocity and acceleration of jo...
Tensile properties in collagen-rich tissues of Quarter Horses with hereditary equine regional dermal asthenia (HERDA).
Equine veterinary journal    August 30, 2013   Volume 46, Issue 2 216-222 doi: 10.1111/evj.12110
Bowser JE, Elder SH, Pasquali M, Grady JG, Rashmir-Raven AM, Wills R, Swiderski CE.Hereditary equine regional dermal asthenia (HERDA) is an autosomal recessive disorder of Quarter Horses characterised by skin fragility. Horses with HERDA have a missense mutation in peptidyl-prolyl cis-trans isomerase B (PPIB), which encodes cyclophilin B and alters folding and post translational modifications of fibrillar collagen. Objective: The study aimed to test the hypothesis that tendons, ligaments and great vessels, which, like skin, are rich in fibrillar collagen, will also have abnormal biomechanical properties in horses with HERDA. Methods: Ex vivo biomechanical study comparing...
Ultrasound-guided biopsy of the cricoarytenoideus lateralis muscle: technique and safety in horses.
Equine veterinary journal    August 30, 2013   Volume 46, Issue 2 244-248 doi: 10.1111/evj.12105
O'Neill HD, Ballegeer EA, De Feijter-Rupp HL, Stick JA, Derksen FJ, Robinson NE.Current diagnosis of recurrent laryngeal neuropathy (RLN) depends upon disease recognition in the clinically affected horse. Biopsy of the intrinsic laryngeal muscles may provide a method to identify the changes in fibre-type composition that occur in RLN before clinical signs become apparent. Objective: To develop an ultrasound-guided biopsy technique of the left cricoarytenoideus lateralis muscle (CALM) and evaluate its efficacy and safety in vivo. Methods: A longitudinal descriptive study. Methods: Six standing horses underwent ultrasound-guided biopsy of the left CALM. Frozen muscle cores ...
Effect of forelimb lameness on hoof kinematics of horses at a walk.
American journal of veterinary research    August 28, 2013   Volume 74, Issue 9 1192-1197 doi: 10.2460/ajvr.74.9.1192
Moorman VJ, Reiser RF, Peterson ML, McIlwraith CW, Kawcak CE.To determine kinematic changes to the hoof of horses at a walk after induction of unilateral, weight-bearing forelimb lameness and to determine whether hoof kinematics return to prelameness (baseline) values after perineural anesthesia. Methods: 6 clinically normal Quarter Horses. Methods: For each horse, a sole-pressure model was used to induce 3 grades of lameness in the right forelimb, after which perineural anesthesia was administered to eliminate lameness. Optical kinematics were obtained for both forelimbs with the horse walking before (baseline) and after induction of each grade of lame...
Girth pressure measurements reveal high peak pressures that can be avoided using an alternative girth design that also results in increased limb protraction and flexion in the swing phase.
Veterinary journal (London, England : 1997)    August 20, 2013   Volume 198, Issue 1 92-97 doi: 10.1016/j.tvjl.2013.07.028
Murray R, Guire R, Fisher M, Fairfax V.Girths are frequently blamed for veterinary and performance problems, but research into girth/horse interaction is sparse. The study objectives were (1) to determine location of peak pressure under a range of girths, and (2) to compare horse gait between the horse's standard girth and a girth designed to avoid detected peak pressure locations. In the first part of the study, and following validation procedures, a calibrated pressure mat placed under the girth of 10 horses was used to determine the location of peak pressures. A girth was designed to avoid peak pressure locations (Girth F). In t...
Physiological responses of young thoroughbred horses to intermittent high-intensity treadmill training.
Acta veterinaria Scandinavica    August 17, 2013   Volume 55, Issue 1 59 doi: 10.1186/1751-0147-55-59
Ohmura H, Matsui A, Hada T, Jones JH.Training of young Thoroughbred horses must balance development of cardiopulmonary function and aerobic capacity with loading of the musculoskeletal system that can potentially cause structural damage and/or lameness. High-speed equine treadmills are sometimes used to supplement exercise on a track in the training of young Thoroughbreds because the horse can run at high speeds but without the added weight of a rider. We tested the hypothesis that intermittent high-intensity exercise on a treadmill of young Thoroughbred horses entering training can enhance development of aerobic capacity (VO2max...
Comparison of the moment at the distal interphalangeal joint on asphalt and on sand in horses at trot.
Computer methods in biomechanics and biomedical engineering    August 16, 2013   Volume 16 Suppl 1 142-144 doi: 10.1080/10255842.2013.815980
Camus M, Pourcelot P, Falala S, Ravary-Plumioen B, Poupot M, Denoix JM, Chateau H, Crevier-Denoix N.No abstract available
Preliminary study of rider back biomechanics.
Computer methods in biomechanics and biomedical engineering    August 16, 2013   Volume 16 Suppl 1 48-49 doi: 10.1080/10255842.2013.815845
Biau S, Gilbert CH, Gouz J, Roquet CH, Fabis J, Leporcq B.No abstract available
External loads on the leading and trailing forelimbs of a jumping horse at landing measured with a dynamometric horseshoe.
Computer methods in biomechanics and biomedical engineering    August 16, 2013   Volume 16 Suppl 1 145-146 doi: 10.1080/10255842.2013.815981
Crevier-Denoix N, Camus M, Falala S, Ravary-Plumioen B, Douilly-Holden L, Robin D, Denoix JM, Chateau H, Pourcelot P.No abstract available
Equine health survey highlights the prevalence of lameness.
The Veterinary record    August 13, 2013   Volume 173, Issue 6 132 doi: 10.1136/vr.f4967
No abstract available
Expression of β2 adrenoceptors within enteric neurons of the horse ileum.
Research in veterinary science    August 12, 2013   Volume 95, Issue 3 837-845 doi: 10.1016/j.rvsc.2013.07.006
Bombardi C, Grandis A, Gardini A, Sorteni C, Clavenzani P, Chiocchetti R.The activity of the gastrointestinal tract is regulated through the activation of adrenergic receptors (ARs). Since data concerning the distribution of ARs in the horse intestine is virtually absent, we investigated the distribution of β2-AR in the horse ileum using double-immunofluorescence. The β2-AR-immunoreactivity (IR) was observed in most (95%) neurons located in submucosal plexus (SMP) and in few (8%) neurons of the myenteric plexus (MP). Tyrosine hydroxylase (TH)-IR fibers were observed close to neurons expressing β2-AR-IR. Since β2-AR is virtually expressed in most neurons located...
Effect of a Pessoa training aid on temporal, linear and angular variables of the working trot.
Veterinary journal (London, England : 1997)    July 30, 2013   Volume 198, Issue 2 404-411 doi: 10.1016/j.tvjl.2013.07.005
Walker VA, Dyson SJ, Murray RC.Development of core muscle strength is important for training and during rehabilitation following injury. A Pessoa training aid (PTA) is a system of ropes and pulleys which is commonly used during equine training and rehabilitation, but there is limited information on its effectiveness. The objective of the study was to determine the effect of the PTA on the temporal, linear and angular kinematics of the working trot. Influence of testing order on effect of a PTA was assessed in four horses. Twelve riding horses were lunged at working trot on a 16 m diameter circle without (WO) and with a PTA ...
Impact of health disorders and culling reasons on functional and biological longevity in Warmblood breeding stallions.
Veterinary journal (London, England : 1997)    July 30, 2013   Volume 197, Issue 2 273-279 doi: 10.1016/j.tvjl.2013.02.026
König von Borstel U, Bernhard V.The objective of this study was to compare the impact of health disorders and reasons for culling on the functional and biological longevity of warmblood breeding stallions using semi-parametric survival analysis accounting for competing risks. Complete breeding records were collected from 455 warmblood stallions serving between 1975 and 2010 at Marbach State Stud in Germany. The median length of life (18.0 years) was twice as long as the median length of service (9.0 years). However, both figures increased significantly over the time period examined (e.g., functional longevity increased from ...
Functional limits of agreement applied as a novel method comparison tool for accuracy and precision of inertial measurement unit derived displacement of the distal limb in horses.
Journal of biomechanics    July 23, 2013   Volume 46, Issue 13 2320-2325 doi: 10.1016/j.jbiomech.2013.06.004
Olsen E, Pfau T, Ritz C.Over ground motion analysis in horses is limited by a small number of strides and restraints of the indoor gait laboratory. Inertial measurement units (IMUs) are transforming the knowledge of human motion and objective clinical assessment through the opportunity to obtain clinically relevant data under various conditions. When using IMUs on the limbs of horses to determine local position estimates, conditions with high dynamic range of both accelerations and rotational velocities prove particularly challenging. Here we apply traditional method agreement and suggest a novel method of functional...
Imaging horse tendons using multimodal 2-photon microscopy.
Methods (San Diego, Calif.)    July 19, 2013   Volume 66, Issue 2 256-267 doi: 10.1016/j.ymeth.2013.07.016
Sivaguru M, Eichorst JP, Durgam S, Fried GA, Stewart AA, Stewart MC.Injuries and damage to tendons plague both human and equine athletes. At the site of injuries, various cells congregate to repair and re-structure the collagen. Treatments for collagen injury range from simple procedures such as icing and pharmaceutical treatments to more complex surgeries and the implantation of stem cells. Regardless of the treatment, the level of mechanical stimulation incurred by the recovering tendon is crucial. However, for a given tendon injury, it is not known precisely how much of a load should be applied for an effective recovery. Both too much and too little loading...
Computed tomographic features of lesions detected in horses with tarsal lameness.
Equine veterinary journal    July 16, 2013   Volume 46, Issue 2 189-193 doi: 10.1111/evj.12097
Raes E, Bergman HJ, Van Ryssen B, Vanderperren K, Stock E, Saunders JH.Tarsal pain is a common cause of hindlimb lameness in horses. Diagnosis can usually be made with radiography and ultrasonography; however, in some cases, these techniques are inconclusive and additional imaging is necessary. No studies describing computed tomography (CT) features of different tarsal lesions in horses with tarsal lameness are reported. Objective: Our aims were as follows: 1) to characterise CT abnormalities in horses with tarsal lameness; 2) to compare CT findings with those from other imaging techniques; and 3) to assess whether CT can help to diagnose tarsal pathology. ...
Non-invasive assessment of equine muscular function: A case study.
Open veterinary journal    July 12, 2013   Volume 3, Issue 2 80-84 
Riis KH, Harrison AP, Riis-Olesen K.Assessment of muscle function after an injury or during recovery is of great importance in the veterinary field. Accelerometry, bioimpedance analysis and mechanomyography/acoustic myography have been used to assess human muscular problems, but have not been applied to the veterinary clinic. We report the clinical use of these techniques in a 12-year-old Danish Warmblood horse presenting with recurring and shifting lameness. Acoustic myography, assessing both the amplitude and frequency of active muscles, was employed to locate the specific area of muscle injury, the right hip, which exhibited ...
IHH gene polymorphism among three horse breeds and its application for association test in horses with osteochondrosis.
Hereditas    July 8, 2013   Volume 150, Issue 2-3 38-43 doi: 10.1111/j.1601-5223.2013.02282.x
Zabek T, Golonka P, Fornal A, Semik E.Genetic polymorphism of IHH gene were investigated in Angloarabian, Polish Coldblood and Polish Halfbred horses with the inclusion of a group of Polish Halfbreds affected by osteochondrosis. IHH is a good candidate gene for association study of developmental disorders mainly affecting skeleton development. DNA sequence spanning IHH gene annotated in the horse genome and its putative promoter were investigated using SANGER sequencing. Analysis of genetic variability at polymorphic sites in the IHH gene body and the promoter region confirmed genetic differences between warmblood and coldblood ho...
Are there radiologically identifiable prodromal changes in Thoroughbred racehorses with parasagittal fractures of the proximal phalanx?
Equine veterinary journal    July 4, 2013   Volume 46, Issue 1 88-91 doi: 10.1111/evj.12093
Smith MR, Wright IM.Fractures of the proximal phalanx are generally considered to result from monotonic supraphysiological loads, but radiological observations from clinical cases suggest there may be a stress-related aetiology. Objective: To determine whether there are radiologically identifiable prodromal changes in Thoroughbred racehorses with confirmed parasagittal fractures of the proximal phalanx. Methods: Retrospective cross-sectional study. Methods: Case records and radiographs of Thoroughbred racehorses with parasagittal fractures of the proximal phalanx were analysed. Thickness of the subchondral bone p...
Morphologic radiographic study of the proximal sesamoid bones of the forelimb in thoroughbred racehorses in training.
Anatomia, histologia, embryologia    June 25, 2013   Volume 43, Issue 5 403-407 doi: 10.1111/ahe.12075
Beccati F, Gialletti R, Giontella A, Davanzo S, Di Meo A, Pepe M.The aim of this study was to identify differences in bone shape (height and width) of proximal sesamoid bones (PSB) in 2-year-old Thoroughbred racehorses in training. Dorsal 15° proximal-palmarodistal oblique images of each metacarpophalangeal joint were acquired before the horses started training and at 1 year after the start of exercise and racing. There were no changes in height and width of PSBs induced by training. There was a significant difference of height and width between medial and lateral PSBs. In both forelimbs, the medial PSB was significantly wider and shorter than the lateral...
Modelling biomechanical requirements of a rider for different horse-riding techniques at trot.
The Journal of experimental biology    June 21, 2013   Volume 216, Issue Pt 10 1850-1861 doi: 10.1242/jeb.070938
de Cocq P, Muller M, Clayton HM, van Leeuwen JL.The simplest model possible for bouncing systems consists of a point mass bouncing passively on a mass-less spring without viscous losses. This type of spring-mass model has been used to describe the stance period of symmetric running gaits. In this study, we investigated the interaction between horse and rider at trot using three models of force-driven spring (-damper)-mass systems. The first system consisted of a spring and a mass representing the horse that interact with another spring and mass representing the rider. In the second spring-damper-mass model, dampers, a free-fall and a forcin...
Are mesenchymal progenitor cells set to revolutionise management of musculoskeletal injuries in the horse?
Veterinary journal (London, England : 1997)    June 15, 2013   Volume 197, Issue 3 533-534 doi: 10.1016/j.tvjl.2013.05.018
Dyson SJ.No abstract available
Therapeutic use of stem cells in horses: which type, how, and when?
Veterinary journal (London, England : 1997)    June 15, 2013   Volume 197, Issue 3 570-577 doi: 10.1016/j.tvjl.2013.04.018
Schnabel LV, Fortier LA, McIlwraith CW, Nobert KM.Stem cells are commonly used in equine practice to treat musculoskeletal disorders including tendonitis, osteoarthritis, and more recently laminitis. As the field of regenerative medicine continues to advance, equine practitioners need contemporary information regarding the choice of stem cell type and recommendations regarding clinical implementation of stem cell therapies. Clinicians must also be aware of the limitation in current knowledge regarding stem cells, and the impending regulatory laws that may limit the use of equine stem cells in clinical patients.
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