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Topic:Public Health

The topic of Public Health and horses encompasses the study of interactions between equine populations and human health systems. It involves examining the transmission of zoonotic diseases, which are diseases that can be transferred between animals and humans, as well as the role of horses in the epidemiology of such diseases. This field also considers the impact of equine-related activities on public health, including injuries and environmental effects. Research in this area often explores preventive measures, management strategies, and policies to mitigate health risks associated with horses. This page compiles peer-reviewed research studies and scholarly articles that investigate the intersection of equine and public health, focusing on disease transmission, risk assessment, and health management strategies.
DEFRA’s proposals on equine dentistry.
The Veterinary record    September 4, 2001   Volume 149, Issue 6 190-191 
House CJ.No abstract available
DEFRA seeks comments on proposals to extend the role of veterinary nurses…and of trained technicians in equine dentistry.
The Veterinary record    August 24, 2001   Volume 149, Issue 5 130-131 
No abstract available
Transmission of opportunistic pathogens in a veterinary teaching hospital.
Veterinary microbiology    August 17, 2001   Volume 82, Issue 4 347-359 doi: 10.1016/s0378-1135(01)00396-0
Boerlin P, Eugster S, Gaschen F, Straub R, Schawalder P.Acinetobacter baumannii, Enterococcus faecalis, Enterococcus faecium, and Staphylococcus intermedius isolates from infected surgical wounds and other types of infections in a veterinary teaching hospital were typed by pulsed field gel electrophoresis. A first cluster of infections with a multiresistant A. baumannii strain was observed in dogs and cats in 1998-1999. This strain disappeared after cleaning and disinfection of the companion animals intensive care unit. It was followed in 2000 by a second multiresistant strain, which caused another cluster of infections and was also transmitted to ...
Trypanosoma evansi control and horse mortality in the Brazilian Pantanal.
Memorias do Instituto Oswaldo Cruz    August 14, 2001   Volume 96, Issue 5 599-602 doi: 10.1590/s0074-02762001000500002
Seidl AF, Moraes AS, Silva RA.The impact of three treatment strategies for Trypanosoma evansi control on horse mortality in the Brazilian Pantanal based on four size categories of cattle ranches is explored. The region's 49,000 horses are indispensable to traditional extensive cattle ranching and T. evansi kills horses. About 13% of these horses would be lost, annually, due to T. evansi if no control were undertaken. One preventive and two curative treatment strategies are financially justifiable in the Pantanal. The best available technology for the treatment of T. evansi from a horse mortality perspective is the preventi...
Candidate vaccine against botulinum neurotoxin serotype A derived from a Venezuelan equine encephalitis virus vector system.
Infection and immunity    August 14, 2001   Volume 69, Issue 9 5709-5715 doi: 10.1128/IAI.69.9.5709-5715.2001
Lee JS, Pushko P, Parker MD, Dertzbaugh MT, Smith LA, Smith JF.A candidate vaccine against botulinum neurotoxin serotype A (BoNT/A) was developed by using a Venezuelan equine encephalitis (VEE) virus replicon vector. This vaccine vector is composed of a self-replicating RNA containing all of the VEE nonstructural genes and cis-acting elements and also a heterologous immunogen gene placed downstream of the subgenomic 26S promoter in place of the viral structural genes. In this study, the nontoxic 50-kDa carboxy-terminal fragment (H(C)) of the BoNT/A heavy chain was cloned into the replicon vector (H(C)-replicon). Cotransfection of BHK cells in vitro with t...
Dispersion of horse allergen in the ambient air, detected with sandwich ELISA.
Allergy    August 8, 2001   Volume 56, Issue 8 771-774 doi: 10.1034/j.1398-9995.2001.056008771.x
Emenius G, Larsson PH, Wickman M, Härfast B.The objective was to establish an ELISA to detect horse allergen in ambient air and settled dust. Methods: Monoclonal antibodies (mAbs) were produced against extracts of horse antigen. Two mAbs were selected and used in a sandwich ELISA. By the aid of portable pumps, air samples were collected in one stable and in the ambient air surrounding this stable. Furthermore, settled dust was collected by wiping spots with pieces of fabric, at sites within 500 m of the stable. Results: Extracts of horsehair could be extensively diluted and still be positive. Extracts of cat and dog allergen failed to b...
Production of potent polyvalent antivenom against three elapid venoms using a low dose, low volume, multi-site immunization protocol.
Toxicon : official journal of the International Society on Toxinology    August 2, 2001   Volume 39, Issue 10 1487-1494 doi: 10.1016/s0041-0101(01)00108-8
Chotwiwatthanakun C, Pratanaphon R, Akesowan S, Sriprapat S, Ratanabanangkoon K.The purpose of this study was to prepare a potent polyvalent antivenom against three elapids namely, the Thai cobra (Naja kaouthia, NK), the King cobra (Ophiophagus hannah, OH) and the banded krait (Bungarus fasciatus, BF). Two groups of horses were immunized. Group 1, comprising five horses, was immunized twice with a mixture of postsynaptic neurotoxins followed by an additional six immunizations with a mixture of crude venoms of the three elapids. Group 2, comprising four horses, was immunized with a mixture of crude venoms throughout the course. For the first immunization, the immunogens we...
Clinical, pathologic, immunohistochemical, and virologic findings of eastern equine encephalomyelitis in two horses.
Veterinary pathology    July 27, 2001   Volume 38, Issue 4 451-456 doi: 10.1354/vp.38-4-451
Del Piero F, Wilkins PA, Dubovi EJ, Biolatti B, Cantile C.Natural eastern equine encephalitis alphavirus (EEEV) infection was diagnosed in two adult horses with anorexia and colic, changes in sensorium, hyperexcitability, and terminal severe depression. Myocardium, tunica muscularis of stomach, intestine, urinary bladder, and spleen capsule had coagulative necrosis and perivascular lymphocytic infiltrate. Central nervous system (CNS) lesions were diffuse polioencephalomyelitis with leptomeningitis characterized by perivascular T lymphocyte cuffing, marked gliosis, neuronophagia, and multifocal microabscesses. Lesions were more prominent within cerebr...
Specific heterologous F(ab’)2 antibodies revert blood incoagulability resulting from envenoming by Lonomia obliqua caterpillars.
The American journal of tropical medicine and hygiene    July 21, 2001   Volume 64, Issue 5-6 283-289 doi: 10.4269/ajtmh.2001.64.283
Rocha-Campos AC, Gonçalves LR, Higashi HG, Yamagushi IK, Fernandes I, Oliveira JE, Ribela MT, Sousa-E-Silva MC, da Silva WD.Contact with Lonomia obliqua caterpillars results in a bleeding syndrome characterized by hemorrhage and blood coagulation disturbances. Conventional therapy using antifibrinolytics or cryoprecipitates has been unable to treat pathophysiologic alterations. As antivenoms are effective therapy for treatment of victims of venomous animals, a process of manufacturing a specific antilonomic serum by immunizing horses with Lonomia caterpillar bristle extracts (LBE) was developed. Lonomia caterpillar bristle extracts exhibited several protein bands on SDS-PAGE, induced blood coagulation abnormalities...
[Prevalence of the Salmonella plasmid virulence gene “spvD” in Salmonella strains from animals].
DTW. Deutsche tierarztliche Wochenschrift    July 14, 2001   Volume 108, Issue 6 243-245 
Bauerfeind R, Barth S, Weiss R, Baljer G.Strains of Salmonella isolated from animals in Germany (n = 878) were analysed for the presence of the spvD gene ("Salmonella plasmid virulence gene D") by DNA-DNA hybridization. The spvD gene was only detected in strains of serovars Typhimurium (93.3%), Enteritidis (97.1%), and Dublin (100%) as well as in two rough strains of Salmonella enterica. Salmonella isolates from mammals carried the gene more frequently (cattle 94.0%, horses 92.6%, pigs 73.7%) than those from birds (33.3%) or reptiles (4.5%). Due to its high prevalence in epidemiologically relevant salmonellae, the virulence factor sp...
Borna disease virus-specific circulating immune complexes, antigenemia, and free antibodies–the key marker triplet determining infection and prevailing in severe mood disorders.
Molecular psychiatry    July 10, 2001   Volume 6, Issue 4 481-491 doi: 10.1038/sj.mp.4000909
Bode L, Reckwald P, Severus WE, Stoyloff R, Ferszt R, Dietrich DE, Ludwig H.Borna disease virus (BDV), a unique genetically highly conserved RNA virus (Bornaviridae; Mononegavirales), preferentially targets neurons of limbic structures causing behavioral abnormalities in animals. Markers and virus in patients with affective disorders and schizophrenia have raised worldwide interest. A persistent infection was suggestive from follow-up studies, but inconstant detectability weakened a possible linkage.This study for the first time discloses that detection gaps are caused by BDV-specific circulating immune complexes (CIC), and their interplay with free antibodies and pla...
Caterpillars, cherry trees may take blame for foal deaths in Kentucky.
Journal of the American Veterinary Medical Association    July 7, 2001   Volume 219, Issue 1 13-14 
No abstract available
[Legal liability of the owner of a horse for injury to a veterinarian].
Tijdschrift voor diergeneeskunde    July 5, 2001   Volume 126, Issue 12 431 
Bruyninckx EL, Boissevain I.No abstract available
[Equine estrogens vs. esterified estrogens in the climacteric and menopause. The controversy arrives in Mexico].
Gaceta medica de Mexico    July 4, 2001   Volume 137, Issue 3 237-242 
Velasco-Murillo V.It exists controversies about if the effects and benefits of the esterified estrogens could be similar to those informed for equines, because its chemical composition and bioavailability are different. Esterified estrogens has not delta 8,9 dehydroestrone, and its absorption and level of maximum plasmatic concentrations are reached very fast. In United States of America and another countries, esterified estrogens has been marketed and using for treatment of climacteric syndrome and prevention of postmenopausal osteoporosis, based on the pharmacopoiea of that country, but the Food and Drug admi...
Lack of antibodies to porcine circovirus type 2 virus in beef and dairy cattle and horses in western Canada.
The Canadian veterinary journal = La revue veterinaire canadienne    June 27, 2001   Volume 42, Issue 6 461-464 
Ellis JA, Konoby C, West KH, Allan GM, Krakowka S, McNeilly F, Meehan B, Walker I.Porcine circovirus type 2 (PCV2) is a recently recognized agent that is consistently associated with postweaning multisystemic wasting disease in swine. There are conflicting data concerning the ability of this virus to infect and cause disease in other species. To determine if normal cattle, cattle affected with various illnesses, and normal horses in endemic areas of PCV2 infection in swine have had PCV2 infections, 100 randomly selected bovine sera, 100 equine sera, and 100 colostrum samples from clinically normal dairy cattle were examined for the presence of antibodies to porcine circovir...
Characterisation of Rhodococcus equi strains isolated from foals and from immunocompromised human patients.
Acta veterinaria Hungarica    June 14, 2001   Volume 48, Issue 3 253-259 
Makrai L, Fodor L, Csivincsik A, Varga J, Senoner Z, Szabó B.The cultural, morphological, biochemical, serological characteristics and antibiotic susceptibility of 25 Rhodococcus equi strains isolated from lungs and lung abscesses of pneumonic foals and 5 R. equi strains isolated from immuno-compromised human patients were examined. All R. equi strains showed common cultural, morphological and biochemical characteristics both with conventional tests and on the basis of their enzyme profile. The R. equi strains examined were resistant to penicillins with the exception of ampicillin, to sulphamethazine and several strains also to sulphamethoxazole-trimeth...
West Nile virus encephalomyelitis in eight horses.
Journal of the American Veterinary Medical Association    June 8, 2001   Volume 218, Issue 10 1576-1579 doi: 10.2460/javma.2001.218.1576
Snook CS, Hyman SS, Del Piero F, Palmer JE, Ostlund EN, Barr BS, Desrochers AM, Reilly LK.No abstract available
Intranasal immunogenicity of a Delta cya Delta crp-pabA mutant of Salmonella enterica serotype Typhimurium for the horse.
Vaccine    June 8, 2001   Volume 19, Issue 27 3787-3795 doi: 10.1016/s0264-410x(01)00091-3
Sheoran AS, Timoney JF, Tinge SA, Sundaram P, Curtiss R.The aim of this study was to investigate the intranasal immunogenicity for the horse of a Deltacya Deltacrp-pabA mutant (MGN-707) of Salmonella enterica serotype Typhimurium (S. typhimurium). MGN-707 caused no sign of disease, was not detected in feces and a single administration induced strong Salmonella-specific serum and nasal mucosal antibody responses. All ponies had made strong salmonella specific serum IgGa, IgGb, IgA and IgM antibody responses by day 25 after the first immunization. IgM responses to salmonella lipopolysaccharide (LPS) were short lived whereas salmonella specific serum ...
An equine mystery in the bluegrass. An epidemic is killing Kentucky’s finest foals.
U.S. news & world report    June 1, 2001   Volume 130, Issue 21 42-43 
Hayden T.No abstract available
Cadmium accumulation and distribution in slaughtered horse kidneys from the Argentine central region.
Archives of environmental contamination and toxicology    June 1, 2001   Volume 41, Issue 1 100-103 doi: 10.1007/s002440010225
Beldoménico HR, Baroni E, Campagnoli DU, Sigrist ME, Rubio M, Boggio JC.In this paper we report the results of surveys conducted in Argentina between 1997 and 1998 to know the Cd concentrations in kidney from horses of different age, sex, and origin. Cd in renal cortex and medulla was positively correlated, and higher concentrations in the cortex were found. No significant differences between values from left and right kidneys of the same animal were found. An increase in Cd levels with age of animals were observed, and no sex incidence was verified in renal Cd composition. No detectable residues were found in the fetuses tested. Levels observed in Argentine equin...
Application of Sartwell’s model (lognormal distribution of incubation periods) to age at onset and age at death of foals with Rhodococcus equi pneumonia as evidence of perinatal infection.
Journal of veterinary internal medicine    May 31, 2001   Volume 15, Issue 3 171-175 doi: 10.1892/0891-6640(2001)0152.3.co;2
Horowitz ML, Cohen ND, Takai S, Becu T, Chaffin MK, Chu KK, Magdesian KG, Martens RJ.The distributions of the incubation periods for infectious and neoplastic diseases originating from point-source exposures, and for genetic diseases, follow a lognormal distribution (Sartwell's model). Conversely, incubation periods in propagated outbreaks and diseases with strong environmental components do not follow a lognormal distribution. In this study Sartwell's model was applied to the age at onset and age at death of foals with Rhodococcus equi pneumonia. The age at onset of clinical signs and age at death were compiled for 107 foals that had been diagnosed with R. equi pneumonia at b...
Streptococcal meningitis resulting from contact with an infected horse.
Journal of clinical microbiology    May 29, 2001   Volume 39, Issue 6 2358-2359 doi: 10.1128/JCM.39.6.2358-2359.2001
Downar J, Willey BM, Sutherland JW, Mathew K, Low DE.We report a case of group C streptococcal meningitis in a woman with a history of close animal contact as well as head trauma as a result of a kick by a horse. Blood and cerebrospinal fluid cultures grew Streptococcus equi subsp. zooepidemicus, as did a throat culture taken from the colt that had kicked her 2 weeks prior to admission.
Discovery and occurrence of the fumonisins: a historical perspective.
Environmental health perspectives    May 22, 2001   Volume 109 Suppl 2, Issue Suppl 2 239-243 doi: 10.1289/ehp.01109s2239
Marasas WF.This article describes the events leading to the discovery of the fumonisins in South Africa in 1988 and highlights the first 10 years (1988-1998) of fumonisin research. The predominant fungus isolated from moldy corn implicated in a field outbreak of equine leukoencephalomalacia (ELEM) in South Africa in 1970 was Fusarium verticillioides (F. moniliforme). This fungus was also prevalent in moldy home-grown corn consumed by people in high-incidence areas of esophageal cancer (EC) in the Transkei region of South Africa. Culture material on corn of F. verticillioides strain MRC 826, which was iso...
The West Nile virus: its recent emergence in North America.
Microbes and infection    May 19, 2001   Volume 3, Issue 3 223-229 doi: 10.1016/s1286-4579(01)01374-0
Garmendia AE, Van Kruiningen HJ, French RA.West Nile fever emerged in New York in the summer of 1999 when seven people, several horses and thousands of wild birds died. It was soon established that the human disease and the mortality of birds were related. Continued surveillance detected West Nile virus in mosquitoes, birds, horses, small mammals, bats and humans, and has shown its spread to several northeastern states. These events confirm the establishment of West Nile virus endemically in the United States.
A horse is not a large rat: getting toxicology into perspective.
Veterinary journal (London, England : 1997)    May 16, 2001   Volume 161, Issue 3 222-223 doi: 10.1053/tvjl.2001.0578
Miert AV.No abstract available
Arbovirus surveillance in South Carolina, 1996-98.
Journal of the American Mosquito Control Association    May 10, 2001   Volume 17, Issue 1 73-78 
Wozniak A, Dowda HE, Tolson MW, Karabatsos N, Vaughan DR, Turner PE, Ortiz DI, Wills W.Arboviruses isolated and identified from mosquitoes in South Carolina (USA) are described, including new state records for eastern equine encephalitis virus (EEE), St. Louis encephalitis virus (SLE), Flanders virus, Tensaw virus (TEN), and a variant of Jamestown Canyon virus (JC). Mosquitoes were collected at 52 locations in 30 of 46 South Carolina counties beginning in June 1996, and ending in October 1998, and tested for arboviruses. Of 1,329 mosquito pools tested by virus isolation (85,806 mosquitoes representing 34 mosquito species or complexes), 15 pools were positive. Virus isolations in...
Authors do not believe article provides evidence of vaccine efficacy.
American journal of veterinary research    May 9, 2001   Volume 62, Issue 5 648 
Morley PS, Townsend HG, Haines DM.No abstract available
Risk factors to tick infestations and their occurrence on horses in the state of São Paulo, Brazil.
Veterinary parasitology    May 5, 2001   Volume 97, Issue 1 1-14 doi: 10.1016/s0304-4017(01)00387-9
Labruna MB, Kerber CE, Ferreira F, Faccini JL, De Waal DT, Gennari SM.From December 1998 to March 1999, 40 stud farms were studied in the state of São Paulo, Brazil. During visits to farms, horses reared under grazing conditions were examined for the presence of ticks. On each farm visit, horse pastures were closely inspected and a questionnaire was given to the farm supervisor with the purpose of gaining information about ecological and management variables (independent variables) that could be associated with the presence and infestation levels of ticks on the farm (dependent variables). Three tick species were found during the study. Anocentor nitens, Amblyo...
New approaches for validation of lethal phenotypes and genetic reversion in Helicobacter pylori.
Helicobacter    May 1, 2001   Volume 6, Issue 1 15-23 doi: 10.1046/j.1523-5378.2001.00001.x
McDaniel TK, Dewalt KC, Salama NR, Falkow S.Because of limited genetic tools for use in Helicobacter pylori, tests routinely applied in other bacteria for demonstrating a gene's role in viability and other phenotypes have not been applied to this organism. In a mutational study of putative response regulator genes, we aimed to develop such tools for H. pylori. Methods: We attempted to mutate five response regulator genes by allelic exchange insertional mutagenesis. For genes that yielded no viable mutants, a second copy of the gene was inserted into the chromosome via a suicide vector, and it was seen if providing the second copy would ...
Epidemiology of Rhodococcus equi strains on Thoroughbred horse farms.
Applied and environmental microbiology    April 25, 2001   Volume 67, Issue 5 2167-2175 doi: 10.1128/AEM.67.5.2167-2175.2001
Morton AC, Begg AP, Anderson GA, Takai S, Lämmler C, Browning GF.Pulsed-field gel electrophoresis of restriction endonuclease-digested genomic DNA from a large collection of clinical isolates of Rhodococcus equi, an important pathogen of foals, was used to compare strain distribution between farms and over time. Forty-four strains were found among 209 isolates, with 5 of these accounting for over half the isolates and the 22 strains isolated more than once accounting for 90% of the isolates. The average genotypic diversity on each farm and in each year was found to be less than the genotypic diversity of the isolates taken as a whole, with 5.2% of the total...