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Topic:Retrospective Study

Retrospective studies in horses involve the analysis of pre-existing data to identify patterns, outcomes, and associations related to health and disease within equine populations. These studies utilize historical records, such as veterinary medical histories, treatment outcomes, and diagnostic results, to explore various aspects of equine health and management. Retrospective studies can provide insights into the prevalence of diseases, the effectiveness of treatments, and risk factors associated with certain conditions. This page aggregates peer-reviewed research studies and scholarly articles that focus on the methodologies, findings, and implications of retrospective analyses in equine veterinary science.
A retrospective histologic study of 140 cases of clinically significant equine ocular disorders. Flores MM, Del Piero F, Habecker PL, Langohr IM.Ocular diseases are an important category in equine medicine; however, most articles regarding histologic ocular lesions in horses are exclusive to a specific condition and do not provide a complete review of clinically significant ocular disease frequency in a diagnostic laboratory. We reviewed sections of equine eyes from 140 cases (98 enucleations [biopsies] and 42 autopsies) with clinically relevant ocular alterations at 2 diagnostic centers in the United States. The most common primary conditions were non-traumatic keratitis (36), equine recurrent uveitis (ERU; 31), traumatic injuries (22...
Mortality, clinical findings, predisposing factors and treatment of Clostridioides difficile colitis in Japanese thoroughbred racehorses.
The Veterinary record    March 22, 2020   Volume 187, Issue 2 e14 doi: 10.1136/vr.105605
Nomura M, Kuroda T, Tamura N, Muranaka M, Niwa H.Although Clostridioides difficile-associated diseases (CDAD) is considered to be associated with colitis in horses, few studies have been performed with a focus on the characteristics of CDAD in thoroughbred racehorses. Between 2010 and 2018, a test for C. difficile was performed using faecal samples from 137 thoroughbred racehorses with colitis presenting with diarrhoea and fever. The mortality rate, clinical findings, predisposing factors and the selected treatments were investigated in a retrospective manner. Twenty-four cases were diagnosed as CDAD and 113 as non-CDAD. The mortality rate w...
Clinical findings, diagnoses, and outcomes of horses presented for colic to a referral hospital in Atlantic Canada (2000-2015).
The Canadian veterinary journal = La revue veterinaire canadienne    March 14, 2020   Volume 61, Issue 3 281-288 
Kaufman JM, Nekouei O, Doyle AJ, Biermann NM.Medical records of equine patients presented for signs of abdominal pain to the Atlantic Veterinary College Teaching Hospital between 2000 and 2015 were reviewed. A total of 575 patients were enrolled, and the most common clinical findings, diagnoses, and outcomes are described. Potential predictors of survival to discharge were assessed. The most common diagnosis was large colon impaction (18.4%), followed by large colon volvulus (6.2%). Overall survival to discharge was 69%. The survival rates for horses were 82.9% for those with no diagnosis, 74.6% for those with large intestine lesions, an...
Standing MRI lesions of the distal interphalangeal joint and podotrochlear apparatus occur with a high frequency in warmblood horses. Gutierrez-Nibeyro SD, Werpy NM, Gold SJ, Olguin S, Schaeffer DJ.Foot pain is a common presenting complaint in Warmblood horses. The aim of this retrospective, cross-sectional study was to determine the spectrum of foot lesions detected by magnetic resonance imaging (MRI) in Warmblood horses used for dressage, jumping, and eventing. The medical records of 550 Warmblood horses with foot pain that were scanned using standing MRI were reviewed and the following data were recorded: signalment, occupation, lameness, diagnostic analgesia, imaging results, treatments, and follow-up assessments. Associations between standing MRI lesions and chronic lameness followi...
Racing performance after surgical repair of medial condylar fracture of the third metacarpal/metatarsal bone in thoroughbred racehorses.
Veterinary surgery : VS    March 4, 2020   Volume 49, Issue 4 648-658 doi: 10.1111/vsu.13403
Boorman S, Richardson DW, Hogan PM, Stefanovski D, Levine DG.To report the performance of thoroughbred racehorses after surgical repair of a medial condylar fracture of the third metacarpal/metatarsal bone. Methods: Retrospective cohort study. Methods: Forty-three horses surgically treated for medial condylar fractures, 30 with previous racing experience, 13 without previous racing experience (nonexperienced). Methods: Medical records (2009-2017) were reviewed for signalment, radiographic fracture characteristics, repair technique, and postoperative morbidity and mortality. Each experienced horse was matched with two horses randomly selected from its mo...
Higher body mass index may increase the risk for the development of incisional complications in horses following emergency ventral midline celiotomy.
Equine veterinary journal    February 21, 2020   Volume 52, Issue 6 799-804 doi: 10.1111/evj.13242
Hill JA, Tyma JF, Hayes GM, Radcliffe R, Fubini SL.Obesity is common in the equine population and it has been associated with increased surgical morbidity and mortality in humans. The effect of increased body mass index (BMI) on the incidence of surgical site infections has not been investigated in horses. Objective: To determine whether horses with increased body fat, as estimated by BMI, are more likely to develop post-operative complications, particularly incisional complications, following emergency ventral midline celiotomy. Methods: Retrospective, multi-institutional clinical study. Methods: Medical records of horses >2 years old presen...
Sagittal plane slab fractures of the third carpal bone in 45 racing Thoroughbred horses.
Equine veterinary journal    February 19, 2020   Volume 52, Issue 5 692-698 doi: 10.1111/evj.13230
Tallon R, O'Neill H, Bladon B.Sagittal plane slab fractures of the third carpal bone are a recognised injury in the racehorse. Currently no published data exist for the UK Thoroughbred racehorse population. Objective: To document return to racing following sagittal slab fracture of the third carpal bone in a UK-based racehorse population, and to compare conservative and surgical management. Methods: Single centre retrospective study. Methods: Computerised medical and racing records were searched over a 15-year period for Thoroughbred racehorses with a simple sagittal slab fracture of the third carpal bone. Horses with comm...
Using time-series analysis techniques to enhance the understanding of musculoskeletal injury in Thoroughbred racehorses.
Equine veterinary journal    February 18, 2020   Volume 52, Issue 5 699-708 doi: 10.1111/evj.13220
Johnston AS, Riggs CM, Cogger N, Benschop J, Rogers CW, Rosanowski SM.Many racing jurisdictions monitor race-day musculoskeletal injury (MSI) but fail to evaluate injuries occurring during training. Additionally, previous risk factor analyses have failed to explore temporal trends in injury occurrence. Objective: To use time-series analysis techniques to identify trends, cyclicity and peaks in MSI incidence, in racehorses training and racing at the Hong Kong Jockey Club (HKJC) from July 2010 to June 2018. Methods: Retrospective longitudinal study. Methods: The monthly incidence of all MSI, superficial digital flexor tendon (SDFT) injury, suspensory ligament inju...
Changing policy to treat foals with Rhodococcus equi pneumonia in the later course of disease decreases antimicrobial usage without increasing mortality rate.
Equine veterinary journal    February 17, 2020   Volume 52, Issue 4 531-537 doi: 10.1111/evj.13219
Arnold-Lehna D, Venner M, Berghaus LJ, Berghaus R, Giguère S.There is a lack of data on the efficacy of treatment of Rhodococcus equi pneumonia in association with an optimised selection of foals. Objective: To evaluate whether targeted treatment protocols resulting in decreased antimicrobial use impact foal mortality rates. Methods: Retrospective study. Methods: Three hundred and thirty foals with pneumonia per year were randomly selected from 2008 to 2016. All foals were examined once weekly from birth until weaning. A physical examination of the respiratory tract, body temperature, haematology and an ultrasonographic examination of the lungs was incl...
A Retrospective Survey of Factors Affecting the Risk of Incidents and Equine Injury During Non-Commercial Transportation by Road in the United Kingdom.
Animals : an open access journal from MDPI    February 12, 2020   Volume 10, Issue 2 288 doi: 10.3390/ani10020288
Hall C, Kay R, Green J.The number of equines injured as a result of incidents during road transport is currently unknown in the United Kingdom. Although previous research has identified factors that affect an equine's behavioural and physiological responses to transportation, their contribution to incident occurrence and injury risk is unclear. The aim of this study was to identify factors associated with incident occurrence and equine injury during transportation by road. An online survey was administered between 12th May 2017 and 21st July 2017 in the UK. The survey was open to those transporting equines non-comme...
Computed tomography characteristics of equine paranasal sinus cysts.
Equine veterinary journal    February 12, 2020   Volume 52, Issue 4 538-546 doi: 10.1111/evj.13212
Ostrowska J, Lindström L, Tóth T, Hansson K, Uhlhorn M, Ley CJ.Computed tomography (CT) is commonly used to investigate equine paranasal sinus disease, however, only limited information is available in the literature about the detailed CT appearance of equine paranasal sinus cysts. Objective: To investigate if paranasal sinus cysts have specific characteristics in CT images that allow differentiation from other sinus diseases. Methods: Retrospective observational study. Methods: Evaluation and comparison of CT studies of eight horses with surgically and/or histopathologically confirmed paranasal sinus cysts and 10 horses with other confirmed paranasal sin...
Subchondral lucencies of the proximal tibia in 17 horses.
Veterinary surgery : VS    February 7, 2020   Volume 49, Issue 4 778-786 doi: 10.1111/vsu.13387
Santschi EM, Whitman JL, Prichard MA, Lopes MAF, Pigott JH, Brokken MT, Jenson PW, Johnson CR, Morrow C, Brusie RW, Juzwiak JS, Morehead JP.To describe subchondral lucencies (SCL) in the equine proximal tibia, several treatment options, and clinical outcomes. Methods: Retrospective study. Methods: Seventeen horses with proximal tibial SCL. Methods: Medical record and radiograph review. Follow-up was obtained via examination and radiography when possible and by telephone and race records when required. The median duration of follow-up was 20 months (range, 0-48). Results: Proximal tibial SCL were associated with lameness in 14 of 17 horses. Subchondral lucencies were primary in 11 horses and secondary to an ipsilateral medial fem...
Accuracy of transcranial magnetic stimulation and a Bayesian latent class model for diagnosis of spinal cord dysfunction in horses.
Journal of veterinary internal medicine    February 6, 2020   Volume 34, Issue 2 964-971 doi: 10.1111/jvim.15699
Rijckaert J, Raes E, Buczinski S, Dumoulin M, Deprez P, Van Ham L, van Loon G, Pardon B.Spinal cord dysfunction/compression and ataxia are common in horses. Presumptive diagnosis is most commonly based on neurological examination and cervical radiography, but the interest into the diagnostic value of transcranial magnetic stimulation (TMS) with recording of magnetic motor evoked potentials has increased. The problem for the evaluation of diagnostic tests for spinal cord dysfunction is the absence of a gold standard in the living animal. Objective: To compare diagnostic accuracy of TMS, cervical radiography, and neurological examination. Methods: One hundred seventy-four horses ad...
Description of a rare osteochondrosis lesion of the medial aspect of the distal intermediate ridge of the tibia in seven Thoroughbred horses (2008-2018). Kadic LIM, Rodgerson DH, Newsom LE, Spirito MA.Osteochondritis dissecans (OCD) of the distal intermediate ridge of the tibia (DIRT) is commonly identified on either the lateral to medial (LM) or dorso45°medial-plantarolateral oblique (D45M-PLO) projection of the tarsus. This manuscript describes a retrospective case series out of Hagyard Equine Medical Institute, for which medical records and radiographic projections of the tarsus were reviewed, consistent with Keeneland's repository requirements. This original investigation identified seven yearling Thoroughbred horses between 2008 and 2018 with radiographic signs of atypical osteochondr...
Differences in isolation rate and antimicrobial susceptibility of bacteria isolated from foals with sepsis at admission and after ≥48 hours of hospitalization.
Journal of veterinary internal medicine    February 5, 2020   Volume 34, Issue 2 955-963 doi: 10.1111/jvim.15692
Theelen MJP, Wilson WD, Byrne BA, Edman JM, Kass PH, Mughini-Gras L, Magdesian KG.Antimicrobial treatment protocols for foals with sepsis that do not improve clinically often are adjusted based on bacteriological and antimicrobial susceptibility testing results from samples collected at hospital admission. Objective: To evaluate whether hospitalization for ≥48 hours affects bacteriological and antimicrobial susceptibility testing results. Methods: Two-hundred sixty-seven foals <30 days of age admitted to a neonatal intensive care unit and diagnosed with sepsis. Methods: Medical records were reviewed retrospectively to identify foals with sepsis and positive bacteri...
Management of postoperative dysphagia after prosthetic laryngoplasty or arytenoidectomy.
Veterinary surgery : VS    February 4, 2020   Volume 49, Issue 3 529-539 doi: 10.1111/vsu.13389
Luedke LK, Cheetham J, Mohammed HO, Ducharme NG.To evaluate the efficacy of various treatments for dysphagia after laryngeal surgery. Methods: Retrospective. Methods: Horses treated for dysphagia after laryngeal surgery. Methods: Medical records of horses treated for dysphagia after prosthetic laryngoplasty (PLP) or partial arytenoidectomy (PA) were reviewed. Signalment, prior surgery, preoperative videoendoscopic diagnosis, and surgical treatments were recorded. Short- and long-term follow-up were obtained. Chi-square and logistical regression were performed to correlate independent variables and outcomes. Results: Forty-four percent of ho...
Childhood horse and donkey bites; a single tertiary health center experience in a rural area.
Avicenna journal of medicine    January 23, 2020   Volume 10, Issue 1 1-5 doi: 10.4103/ajm.ajm_158_19
Bucak IH, Turgut K, Almis H, Turgut M.The aim of this study was to examine the characteristics of patients presenting to a pediatric emergency department in a rural province of Turkey due to horse and donkey bites and to analyze whether these features differ from those of more common animal bites in rural areas. Methods: The records of patients presenting to the pediatric emergency department of a tertiary hospital due to horse and donkey bites over a 3-year period were examined retrospectively. Demographic data, month of presentation, animal species involved (horse or donkey), the body area bitten, treatment applied to the wound ...
Risk Factors of Anesthesia-Related Mortality and Morbidity in One Equine Hospital: A Retrospective Study on 1,161 Cases Undergoing Elective or Emergency Surgeries.
Frontiers in veterinary science    January 22, 2020   Volume 6 514 doi: 10.3389/fvets.2019.00514
Laurenza C, Ansart L, Portier K.A retrospective analysis was performed to determine mortality and morbidity rates for elective and emergency cases in an equine university teaching hospital. It investigated the effect of horse-, anesthetic-, timing, and clinician experience-related variables on anesthetic complications. In total, 1,161 horses undergoing general anesthesia between January 2012 and December 2016 were included in the study. Patient information and details of the anesthetic, recovery period and immediate complications were retrieved from an archival database. Statistical analysis of qualitative and quantitative f...
Retrospective assessment of perioperative antimicrobial use for elective arthroscopy in horses.
Veterinary surgery : VS    January 17, 2020   Volume 49, Issue 3 427-435 doi: 10.1111/vsu.13382
Muntwyler N, Dubois MS, Weese JS.To describe perioperative antimicrobial use in horses undergoing elective arthroscopy. Methods: Retrospective study. Methods: Horses that underwent elective arthroscopy at one institution between July 2016 and May 2018, excluding those with a suspected infectious orthopedic disease or with a comorbidity that may have impacted prophylactic antimicrobial use decisions. Methods: Medical records were reviewed to evaluate preoperative, intraoperative, and postoperative antimicrobial drug selection, dose, and timing. Associations between body weight and underdosing were evaluated by using analysis o...
A study investigating the treatment of equine squamous gastric disease with long-acting injectable or oral omeprazole.
Veterinary medicine and science    January 16, 2020   Volume 6, Issue 2 235-241 doi: 10.1002/vms3.220
Gough S, Hallowell G, Rendle D.Equine squamous gastric disease (ESGD) is a highly prevalent disease in horses, particularly in elite athletes. Some horses respond slowly, or fail to respond, to the licensed treatment, oral omeprazole (ORLO). To compare rates of ESGD healing and improvement between ORLO and a long-acting injectable omeprazole preparation (LAIO). Retrospective clinical study. The case records and gastroscopy images of horses presenting to Rainbow Equine Hospital over a 12-month period were reviewed, with images being reviewed blind by one of the authors (David Rendle). Treatment responses were compared betwe...
Retrospective Identification of Bacterial Isolates From Emergency Laparotomy Surgical Site Infections in Horses.
Journal of equine veterinary science    January 15, 2020   Volume 87 102927 doi: 10.1016/j.jevs.2020.102927
Dziubinski N, Mählmann K, Lübke-Becker A, Lischer C.Surgical site infection (SSI) with multiresistant bacteria is an important cause of postoperative morbidity after laparotomy in horses. The objective of this study was to identify bacteria isolates and their antibiotic resistance patterns associated with the development of wound infection in horses after laparotomy. This is a retrospective case series. Medical records of horses that underwent ventral midline exploratory laparotomy in a four-year period at one equine hospital were reviewed. Results of microbiologic culture and susceptibility testing are described. The study group consisted of 1...
Long-term outcome and effect of diagnostic analgesia in horses undergoing interspinous ligament desmotomy for overriding dorsal spinous processes.
Veterinary surgery : VS    January 9, 2020   Volume 49, Issue 3 590-599 doi: 10.1111/vsu.13377
Brown KA, Davidson EJ, Ortved K, Ross MW, Stefanovski D, Wulster KB, Levine DG.To report the long-term outcome of horses treated with interspinous ligament desmotomy (ISLD) for pain associated with overriding dorsal spinous processes (ORDSP) and determine the influence of preoperative diagnostic analgesia on long-term outcome. Methods: Retrospective study. Methods: Eighteen horses. Methods: Data were collected from horses presenting for ISLD to the University of Pennsylvania New Bolton Center between January 2013 and May 2018. Follow-up of ≥3 months postsurgically was obtained from the owner, trainer, or referring veterinarian. Long-term improvement was compared betw...
What is the Evidence of Hyaluronic Acid and Polyacrylamide Hydrogel in Intra-articular Therapy in Equines? Systematic Literature Review.
Journal of equine veterinary science    January 7, 2020   Volume 86 102909 doi: 10.1016/j.jevs.2019.102909
de Souza AF, Paretsis NF, De Zoppa ALDV.A systematic review was conducted to investigate evidence to support or refute the use of hyaluronic acid and polyacrylamide hydrogel as intra-articular therapy in equines, which are frequent treatment options in the routine of veterinarians of equines in cases of osteoarthritis. In total, 19 studies were included, among clinical and in vitro studies, as well as a retrospective series of cases. The outcomes of the included studies provided fragile evidence supporting the recommendation for intra-articular use of hyaluronic acid. No study was included showing any clinical outcome in diseased s...
Equine Coronavirus-Associated Colitis in Horses: A Retrospective Study.
Journal of equine veterinary science    January 3, 2020   Volume 87 102906 doi: 10.1016/j.jevs.2019.102906
Mattei DN, Kopper JJ, Sanz MG.Equine coronavirus (ECoV) is a known cause of fever, anorexia, and lethargy in adult horses. Although there are multiple reports of ECoV outbreaks, less is known about the clinical presentation of individual horses during a nonoutbreak situation. The purpose of this study was to describe the clinical presentation of horses diagnosed with ECoV infection that were not associated with an outbreak. Medical records of all horses admitted to Washington State University, Veterinary Teaching Hospital, during an 8-year period were reviewed (2010-2018). The five horses included in this study were older ...
Neurosurgical management of head injuries incurred during sports: a single centre experience.
British journal of neurosurgery    January 3, 2020   Volume 34, Issue 2 119-122 doi: 10.1080/02688697.2019.1708267
Hall S, McElligott S, Sadek AR, Griffith C, Waters R, Nader-Sepahi A. Accidents during sporting activities are a common cause of head injury, particularly in children and young adults. Whilst most sporting head injuries are minor, there remains a proportion which is associated with high morbidity and mortality. The epidemiology of sports associated head injuries is variable based on geographical region so the aim of this study was to review the management and outcomes of sporting head injuries managed by a single neurosurgical unit in the South of England. A retrospective review of the Trauma Audit and Research Network database was conducted for all patients ad...
Do riders who wear an air jacket in equestrian eventing have reduced injury risk in falls? A retrospective data analysis.
Journal of science and medicine in sport    January 2, 2020   Volume 23, Issue 5 428-429 doi: 10.1016/j.jsams.2019.12.028
Nylund LE, Sinclair PJ, Hitchens PL, Cobley S.No abstract available
Do riders who wear an air jacket in equestrian eventing have reduced injury risk in falls? A retrospective data analysis.
Journal of science and medicine in sport    January 2, 2020   Volume 23, Issue 5 428-429 doi: 10.1016/j.jsams.2019.12.028
Nylund LE, Sinclair PJ, Hitchens PL, Cobley S.No abstract available
Effect of Timing of Postovulatory Insemination Relative to Human Chorionic Gonadotropin/Buserelin Treatment With 1 Straw of Frozen-Thawed Semen on Mare Fertility.
Journal of equine veterinary science    December 24, 2019   Volume 87 102900 doi: 10.1016/j.jevs.2019.102900
Immonen I, Cuervo-Arango J.The reproductive management of mares for frozen semen artificial insemination (AI) can be costly and labor intensive. Predicting the exact time of ovulation can be challenging even when ovulation-inducing drugs are used. The main objective of this retrospective study was to determine whether there was an effect of interval between examinations to detect ovulation on likelihood of pregnancy and early embryonic loss in mares after postovulatory breeding with a single straw of frozen/thawed semen. The second objective was to determine the efficacy of two different drugs (human chorionic gonadotro...
Symptoms and management of temporohyoid osteoarthropathy and its association with crib-biting behavior in 11 Japanese Thoroughbreds.
Journal of equine science    December 18, 2019   Volume 30, Issue 4 81-85 doi: 10.1294/jes.30.81
Saito Y, Amaya T.There have been few reports about temporohyoid osteoarthropathy in Japanese horses. The aim of this study was to describe the symptoms and management of temporohyoid osteoarthropathy and to investigate its association with crib-biting behavior, which is commonly observed in Japanese horses. The data concerning case details, signs, diagnosis procedures, treatment, and outcomes were collected retrospectively from the medical records of 11 Thoroughbreds with temporohyoid osteoarthropathy. The trainers and owners were asked whether the horses had displayed crib-biting behavior. Nine of the horses ...
Retrospective evaluation of the association between hyponatremia and neurological dysfunction in hospitalized foals (2012-2016): 109 cases.
Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)    December 17, 2019   Volume 30, Issue 1 66-73 doi: 10.1111/vec.12906
Dunkel B, Dodson F, Chang YM, Slovis NM.Hyponatremia and rapid correction of hyponatremia can lead to neurological abnormalities. The objective of the study was to determine whether plasma sodium concentrations (Na ) and speed of correction of hyponatremia are significantly associated with neurological abnormalities in foals. Methods: Retrospective cohort study 2012 to 2016. Methods: Equine hospital. Methods: One hundred and nine foals <6 months old with hyponatremia (Na concentration ≤125 mmol/L). Methods: Case records were reviewed for any foal with hyponatremia. Clinicopathological findings, presence or absence of neurologi...
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