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Topic:Veterinary Care

Veterinary care in horses encompasses the medical and preventive measures taken to maintain and improve the health and well-being of equine patients. It includes a wide range of practices such as routine health examinations, vaccinations, dental care, parasite control, and management of injuries and diseases. Veterinary care also involves diagnostic procedures, surgical interventions, and therapeutic treatments tailored to the specific needs of horses. This page gathers peer-reviewed research studies and scholarly articles that explore various aspects of equine veterinary care, including advancements in diagnostic techniques, treatment protocols, and health management strategies to support the well-being and performance of horses.
Focal experimental injury leads to widespread gene expression and histologic changes in equine flexor tendons.
PloS one    April 2, 2015   Volume 10, Issue 4 e0122220 doi: 10.1371/journal.pone.0122220
Jacobson E, Dart AJ, Mondori T, Horadogoda N, Jeffcott LB, Little CB, Smith MM.It is not known how extensively a localised flexor tendon injury affects the entire tendon. This study examined the extent of and relationship between histopathologic and gene expression changes in equine superficial digital flexor tendon after a surgical injury. One forelimb tendon was hemi-transected in six horses, and in three other horses, one tendon underwent a sham operation. After euthanasia at six weeks, transected and control (sham and non-operated contralateral) tendons were regionally sampled (medial and lateral halves each divided into six 3 cm regions) for histologic (scoring and ...
Relative stiffness of 3 bandage/splint constructs for stabilization of equine midmetacarpal fractures.
Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)    April 2, 2015   Volume 25, Issue 3 379-387 doi: 10.1111/vec.12299
Lutter JD, Cary JA, Stephens RR, Potts LB.Determine the relative stiffness of 3 bandage/splint constructs intended for emergency fracture stabilization. Methods: Experimental model. A single plane free end deflection model was developed to simulate the forces placed on a bandage/splint construct during stabilization of a complete mid-metacarpal bone fracture. The total deflection of the model in one plane was measured following application of 3 different bandage/splint combinations including a classic, 3 layered Robert Jones Bandage (RJB) with a splint placed on the outside of the bandage (RJB-3), an RJB with splint placed after the f...
Comparison of cardiorespiratory variables in dorsally recumbent horses anesthetized with guaifenesin-ketamine-xylazine spontaneously breathing 50% or maximal oxygen concentrations.
The Canadian veterinary journal = La revue veterinaire canadienne    April 2, 2015   Volume 56, Issue 4 387-392 
Karrasch NM, Hubbell JA, Aarnes TK, Bednarski RM, Lerche P.This study compared cardiorespiratory variables in dorsally recumbent horses anesthetized with guaifenesin-ketamine-xylazine and spontaneously breathing 50% or maximal (> 90%) oxygen (O2) concentrations. Twelve healthy mares were randomly assigned to breathe 50% or maximal O2 concentrations. Horses were sedated with xylazine, induced to recumbency with ketamine-diazepam, and anesthesia was maintained with guaifenesin-ketamine-xylazine to effect. Heart rate, arterial blood pressures, respiratory rate, lithium dilution cardiac output (CO), inspired and expired O2 and carbon dioxide partial pr...
Gammaherpesvirus infections in equids: a review.
Veterinary medicine (Auckland, N.Z.)    April 1, 2015   Volume 6 91-101 doi: 10.2147/VMRR.S39473
Marenzoni ML, Stefanetti V, Danzetta ML, Timoney PJ.Although the first equine gammaherpesvirus was identified over 50 years ago, the isolation and characterization of other members of this virus group has been relatively recent. Even so, numerous clinical syndromes have been identified in equid species in association with these viruses. Equid gammaherpesviruses are a genetically heterogeneous viral subfamily, the function of which in host immune modulation and disease pathogenesis has not yet been elucidated. While they share similarities with gammaherpesviruses in humans, the role they play in their relationship with the host is the subject of...
Equine Surgery at the Ontario Veterinary College in the Early 20th Century.
Canadian bulletin of medical history = Bulletin canadien d'histoire de la medecine    April 1, 2015   Volume 32, Issue 1 181-202 doi: 10.3138/cbmh.32.1.181
Woodger K, Stone EA.This article seeks to examine the history of equine surgery at the Ontario Veterinary College (OVC) in the context of the changing horse economy during the first half of the 20th century. We argue that despite the transition to livestock medicine, public health and small animal practice, the horse, especially as a surgical topic, retained a (diminished) place at OVC due to the lucrative new recreational equine market, the deep links between horses and veterinary medicine, and the equine focus for nearly half a century of Dr. W.J.R. Fowler, the College's primary surgical instructor.
Effect of dantrolene premedication on various cardiovascular and biochemical variables and the recovery in healthy isoflurane-anesthetized horses.
American journal of veterinary research    March 31, 2015   Volume 76, Issue 4 293-301 doi: 10.2460/ajvr.76.4.293
McKenzie EC, Di Concetto S, Payton ME, Mandsager RE, Arko M.To determine the effect of dantrolene premedication on various cardiovascular and biochemical variables and recovery in isoflurane-anesthetized horses. Methods: 6 healthy horses. Methods: Each horse was anesthetized twice with a 21- to 28-day washout period between anesthetic sessions. Food was not withheld from horses before either session. During each session, dantrolene (6 mg/kg in 2 L of water) or water (2 L) was administered via a nasogastric tube 1 hour before anesthesia was induced. Anesthesia was maintained with isoflurane for 90 minutes, during which blood gas analyses and lithium-dil...
BEVA seeks assurance on continuation of equine research funding.
The Veterinary record    March 31, 2015   Volume 176, Issue 13 320 doi: 10.1136/vr.h1642
No abstract available
Plasma exchange as a treatment for hyperbilirubinemia in 2 foals with neonatal isoerythrolysis.
Journal of veterinary internal medicine    March 31, 2015   Volume 29, Issue 2 736-738 doi: 10.1111/jvim.12549
Broux B, Lefère L, Deprez P, van Loon G.No abstract available
‘Fly-grazing Bill’ to become law.
The Veterinary record    March 31, 2015   Volume 176, Issue 13 320 doi: 10.1136/vr.h1600
No abstract available
Prevalence and Antibiogram study of Rhodococcus equi in equines of Jammu and Kashmir, India.
Journal of equine science    March 31, 2015   Volume 26, Issue 1 21-24 doi: 10.1294/jes.26.21
Mir IA, Kumar B, Taku A, Bhardwaj RK, Bhat MA, Badroo GA.The present study was conducted to determine the prevalence of Rhodococcus equi infection in equines of Jammu and Kashmir, India, and evaluate the zoonotic threat posed by this organism to equine owners and tourists. One hundred and forty-one samples (98 samples from adult animals ≥5 years old and 43 samples from foals less than 6 months old) were collected in duplicate from nasopharyngeal tract of equines for isolation and direct PCR. A total of 12 isolates of R. equi were recovered, of which 9 were from foals and 3 from adult animals. Therefore, the present study recorded prevalence rates ...
Preliminary investigation of the area under the L-lactate concentration-time curve (LACArea) in critically ill equine neonates.
Journal of veterinary internal medicine    March 31, 2015   Volume 29, Issue 2 659-662 doi: 10.1111/jvim.12559
Wilkins PA, Sheahan BJ, Vander Werf KA, Castagnetti C, Hardy J, Schoster A, Boston RC.A variety of measures of L-lactate concentration ([LAC]) in the blood of critically ill neonatal foals have shown utility as prognostic indicators. These measures, evaluating either the severity of hyperlactatemia or the duration of exposure to hyperlactatemia, perform fairly well and have correctly classified 75-80% of foals examined in several studies. The area under the L-lactate concentration versus time curve (LACArea) encompasses both severity and duration of hyperlactatemia and should improve correct classification of patient survival. Objective: LACArea is larger in nonsurviving critic...
Anti-Müllerian hormone as an indicator of hemi-castrated unilateral cryptorchid horses.
Journal of equine science    March 31, 2015   Volume 26, Issue 1 15-20 doi: 10.1294/jes.26.15
Murase H, Saito S, Amaya T, Sato F, Ball BA, Nambo Y.Anti-Müllerian hormone (AMH), a glycoprotein secreted from the fetal testis, is responsible for regression of the Müllerian duct in the male fetus. The aim of this study was to evaluate the usefulness of serum AMH as a biomarker for diagnosis of cryptorchidism in horses. Serum AMH concentrations were measured in intact stallions, hemi-castrated unilateral cryptorchid stallions, and geldings. In addition, expression of AMH was characterized in cryptorchid testes by immunohistochemistry. Serum AMH was detected in intact stallions (n=11, 13.3 ± 1.8 ng/ml) and in hemi-castrated cryptorchid stal...
Glucocorticoid receptor density and binding affinity in healthy horses and horses with systemic inflammatory response syndrome.
Journal of veterinary internal medicine    March 31, 2015   Volume 29, Issue 2 626-635 doi: 10.1111/jvim.12558
Hoffman CJ, McKenzie HC, Furr MO, Desrochers A.Dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis occurs in horses with systemic inflammatory response syndrome (SIRS). Peripheral resistance to glucocorticoids has not been investigated in horses. Objective: To determine if glucocorticoid receptor (GR) function in horses can be measured using flow cytometry, and to use this information to evaluate HPA axis dynamics. Methods: Eleven healthy adult horses in parts 1 and 2. Ten horses with SIRS and 10 age and sex matched controls in part 3. Methods: Flow cytometry was used to evaluate GR density and binding affinity (BA) in 3 healthy...
Trotter welfare’s protection: A legislative perspective.
Veterinary world    March 30, 2015   Volume 8, Issue 3 427-431 doi: 10.14202/vetworld.2015.427-431
Passantino A, Giannetto C, Passantino L, Piccione G.The Council of Europe's activities in the field of animal welfare are particularly noteworthy and comprise the elaboration of several norms for the protection of animals. Concerning the specific European Directive, Regulations or Convention for the protection of animals, the Authors underline the missing of specifics recommendations concerning the welfare of sport horses and especially of trotters. Guidelines are reported by regulation of equestrian sports. The paper's purpose is to give practical elements to individuate the welfare state and to promote a clear regulation on welfare, care and ...
Pilot experimental study on amniotic epithelial mesenchymal cell transplantation in natural occurring tendinopathy in horses. Ultrasonographic and histological comparison.
Muscles, ligaments and tendons journal    March 27, 2015   Volume 5, Issue 1 5-11 
amnion-derived stem cells are considered a promising alternative source for tendon tissue regeneration. Objective: aims of this paper were to illustrate the ultrasound and histological outcomes following the treatment of acute and chronic superficial digital flexor tendon spontaneous lesions in horses with ovine amniotic epithelial cells xenotransplantation. Methods: six adult horses suffering from unilateral acute (4 cases) and chronic (2 cases) tendinopathy (clinical and ultrasound diagnosis) were enrolled. At baseline, ovine amniotic epithelial cells were grafted, in sterile conditions and ...
A universal approach to determine footfall timings from kinematics of a single foot marker in hoofed animals.
PeerJ    March 26, 2015   Volume 3 e783 doi: 10.7717/peerj.783
Starke SD, Clayton HM.The study of animal movement commonly requires the segmentation of continuous data streams into individual strides. The use of forceplates and foot-mounted accelerometers readily allows the detection of the foot-on and foot-off events that define a stride. However, when relying on optical methods such as motion capture, there is lack of validated robust, universally applicable stride event detection methods. To date, no method has been validated for movement on a circle, while algorithms are commonly specific to front/hind limbs or gait. In this study, we aimed to develop and validate kinemati...
Comprehensive protein profiling of synovial fluid in osteoarthritis following protein equalization.
Osteoarthritis and cartilage    March 26, 2015   Volume 23, Issue 7 1204-1213 doi: 10.1016/j.joca.2015.03.019
Peffers MJ, McDermott B, Clegg PD, Riggs CM.The aim of the study was to characterise the protein complement of synovial fluid (SF) in health and osteoarthritis (OA) using liquid chromatography mass spectrometry (LC-MS/MS) following peptide-based depletion of high abundance proteins. Methods: SF was used from nine normal and nine OA Thoroughbred horses. Samples were analysed with LC-MS/MS using a NanoAcquity™ LC coupled to an LTQ Orbitrap Velos. In order to enrich the lower-abundance protein fractions protein equalisation was first undertaken using ProteoMiner™. Progenesis-QI™ LC-MS software was used for label-free quantification. ...
Identification of Equine Lactadherin-derived Peptides That Inhibit Rotavirus Infection via Integrin Receptor Competition.
The Journal of biological chemistry    March 26, 2015   Volume 290, Issue 19 12403-12414 doi: 10.1074/jbc.M114.620500
Human rotavirus is the leading cause of severe gastroenteritis in infants and children under the age of 5 years in both developed and developing countries. Human lactadherin, a milk fat globule membrane glycoprotein, inhibits human rotavirus infection in vitro, whereas bovine lactadherin is not active. Moreover, it protects breastfed infants against symptomatic rotavirus infections. To explore the potential antiviral activity of lactadherin sourced by equines, we undertook a proteomic analysis of milk fat globule membrane proteins from donkey milk and elucidated its amino acid sequence. Alignm...
Circumferential hoof clamp method of lameness induction in the horse.
Veterinary journal (London, England : 1997)    March 25, 2015   Volume 205, Issue 1 81-86 doi: 10.1016/j.tvjl.2015.03.026
Swaab ME, Mendez-Angulo JL, Groschen DM, Ernst NS, Brown MP, Trumble TN.A circumferential hoof clamp method to induce controlled and reversible lameness in the forelimbs of eight horses was assessed. Peak vertical forces and vertical impulses were recorded using a force plate to verify induced lameness. Video recordings were used by blinded observers to determine subjective lameness using a 0-5 scale and any residual lameness following clamp loosening. Tightening of clamps resulted in consistent, visible lameness in the selected limbs in all horses. Lameness was confirmed by significant decreases from baseline in the peak vertical force (P <0.01). Lameness wa...
Serodiagnosis of Toxoplasma gondii infection in farm animals (horses, swine, and sheep) by enzyme-linked immunosorbent assay using chimeric antigens.
Parasitology international    March 25, 2015   Volume 64, Issue 5 288-294 doi: 10.1016/j.parint.2015.03.004
Ferra B, Holec-Gąsior L, Kur J.Toxoplasma gondii infects all warm-blooded animals including humans, causing serious public health problems and great economic loss in the animal husbandry. Commonly used serological tests for diagnosis of toxoplasmosis involve preparation of whole Toxoplasma lysate antigen (TLA) from tachyzoites. The production of this antigen is associated with high costs and lengthy preparation and the possibility of staff infection. There are also some difficulties in the standardization of such tests. One approach in order to improve the diagnosis of T. gondii infection is to use recombinant chimeric anti...
Horse racing model rules see gradual adoption.
Journal of the American Veterinary Medical Association    March 24, 2015   Volume 246, Issue 4 382-385 
Larkin M.No abstract available
As time goes by. Many advances seen in equine medicine since AAEP’s founding 60 years ago.
Journal of the American Veterinary Medical Association    March 24, 2015   Volume 246, Issue 4 377-378 
Larkin M.No abstract available
Intermediate hosts of Angiostrongylus cantonensis in Tenerife, Spain.
PloS one    March 24, 2015   Volume 10, Issue 3 e0120686 doi: 10.1371/journal.pone.0120686
Martin-Alonso A, Abreu-Yanes E, Feliu C, Mas-Coma S, Bargues MD, Valladares B, Foronda P.The nematode Angiostrongylus cantonensis is the causative agent of human angiostrongyliasis, the main clinical manifestation of which is eosinophilic meningitis. Although this parasite has been found recently in its definitive rat host in Tenerife (Canary Islands, Spain), showing a widespread distribution over the north-east part of the island, there are no available data regarding which snail and/or slug species are acting as intermediate hosts on this island. Consequently, the objective of this work was to determine the possible role of three mollusc species, Plutonia lamarckii, Cornu aspers...
Cryptorchidectomy in equids: 604 cases (1977-2010).
Journal of the American Veterinary Medical Association    March 21, 2015   Volume 246, Issue 7 777-784 doi: 10.2460/javma.246.7.777
Hartman R, Hawkins JF, Adams SB, Moore GE, Fessler JF.To evaluate the management of equids undergoing cryptorchidectomy at a referral hospital. Methods: Retrospective case series. Methods: 604 client-owned equids. Methods: Medical records of all equids undergoing surgical treatment of cryptorchidism from 1977 to 2010 were retrospectively reviewed. Analyses of breed, location of retained testes, accuracy of palpation per rectum for determining the location of retained testes, surgical technique, and postoperative complications were performed. Results: The most frequently affected breed was the Quarter Horse (282/604 [47%]), which was significantly...
Bacterial isolates, antimicrobial susceptibility patterns, and factors associated with infection and outcome in foals with septic arthritis: 83 cases (1998-2013).
Journal of the American Veterinary Medical Association    March 21, 2015   Volume 246, Issue 7 785-793 doi: 10.2460/javma.246.7.785
Hepworth-Warren KL, Wong DM, Fulkerson CV, Wang C, Sun Y.To determine clinical characteristics, clinicopathologic data, and bacterial culture and antimicrobial susceptibility results associated with septic arthritis in foals ≤ 180 days old. Methods: Retrospective case series. Methods: 83 foals with septic arthritis. Methods: Medical records at 2 teaching hospitals between 1998 and 2013 were searched to identify those for foals ≤ 180 days old with confirmed infection of ≥ 1 synovial structure. Data extracted from the records included signalment, clinicopathologic information, bacteriologic culture and antimicrobial susceptibility results, and o...
Rallying together to respond to another bushfire animal emergency.
Australian veterinary journal    March 20, 2015   Volume 93, Issue 1-2 N14-N15 
Pratt G.No abstract available
Not just a number: effect of age on fertility, pregnancy and offspring vigour in thoroughbred brood-mares.
Reproduction, fertility, and development    March 20, 2015   Volume 27, Issue 6 872-879 doi: 10.1071/RD14390
Scoggin CF.Advancing age can adversely affect a thoroughbred brood-mare's reproductive efficiency and influence the commercial and athletic potential of her progeny. Causes for the decline in fertility include decreased oocyte and embryo quality, anatomical defects and endometrial degeneration. In addition, evidence exists that as the age of a dam increases, her foals will be at increased risk of morbidity and mortality during the neonatal period. Health issues can have lasting and deleterious effects on surviving foals, including decreased sale value and reduced athletic performance. The purpose of this...
A Critical Analysis of the British Horseracing Authority’s Review of the Use of the Whip in Horseracing.
Animals : an open access journal from MDPI    March 20, 2015   Volume 5, Issue 1 138-150 doi: 10.3390/ani5010138
Jones B, Goodfellow J, Yeates J, McGreevy PD.There is increasing controversy about the use of the whip as a performance aid in Thoroughbred horseracing and its impact on horse welfare. This paper offers a critical analysis of the British Horseracing Authority's (BHA) 2011 Report Responsible Regulation: A Review of the Use of the Whip in Horseracing. It examines the BHA's process of consultation and use of science and public opinion research through the application of current scientific literature and legal analysis. This analysis suggests that the BHA's findings on the welfare impact and justification for whip use are insufficiently defe...
Intraarterial Injection of Iodinated Contrast Medium for Contrast-Enhanced Computed Tomography of the Equine Head. Carmalt JL, Montgomery J.Minimizing the volume of contrast administered for contrast-enhanced computed tomography (CT) of the equine head is desirable for reducing costs and risks of adverse reactions, however evidence-based studies on the effects of varying volumes on image quality are currently lacking. The objective of the current study was to determine whether low-volume intraarterial administration of contrast medium would result in an equivalent image quality and tissue attenuation vs. high-volume intravenous bolus administration. A prospective cross-over experimental design was used in a sample of six horses. A...
The foot-surface interaction and its impact on musculoskeletal adaptation and injury risk in the horse.
Equine veterinary journal    March 18, 2015   Volume 47, Issue 5 519-525 doi: 10.1111/evj.12420
Parkes RS, Witte TH.The equine limb has evolved for efficient locomotion and high-speed performance, with adaptations of bone, tendon and muscle. However, the system lacks the ability seen in some species to dynamically adapt to different circumstances. The mechanical interaction of the limb and the ground is influenced by internal and external factors including fore-hind mass distribution, lead limb, moving on a curve, shoeing and surface properties. It is unclear which of the components of limb loading have the largest effect on injury and performance but peak load, impact and vibration all play a role. Factors...