Veterinary care in horses encompasses the medical and preventive measures taken to maintain and improve the health and well-being of equine patients. It includes a wide range of practices such as routine health examinations, vaccinations, dental care, parasite control, and management of injuries and diseases. Veterinary care also involves diagnostic procedures, surgical interventions, and therapeutic treatments tailored to the specific needs of horses. This page gathers peer-reviewed research studies and scholarly articles that explore various aspects of equine veterinary care, including advancements in diagnostic techniques, treatment protocols, and health management strategies to support the well-being and performance of horses.
Hill EW, Eivers SS, McGivney BA, Fonseca RG, Gu J, Smith NA, Browne JA, MacHugh DE, Katz LM.The role of molecular signalling pathways in the phenotypic adaptation of skeletal muscle to different exercise stimuli in the Thoroughbred horse has not been reported previously. Objective: To examine CKM, COX4I1, COX4I2 and PDK4 gene expression following high intensity sprint and moderate intensity treadmill exercise stimuli in skeletal muscle of Thoroughbred horses. Methods: Two groups of trained 3-year-old Thoroughbred horses participated. Group A (n = 6 females, n = 3 males) participated in an incremental step test (moderate intensity) to fatigue or HR(max) on a Sato high speed treadmill ...
Scott R, Nankervis K, Stringer C, Westcott K, Marlin D.Water treadmill exercise is often incorporated into rehabilitation programmes for horses yet little is known about the biomechanical and physiological responses to water walking. Objective: To establish whether stride frequency (SF) reached steady state as a result of 6 introductory water treadmill sessions and then to investigate the effect of increasing water height on SF, stride length (SL) and heart rate (HR). Methods: Nine horses with no previous experience of water treadmills completed 6 sessions of walking for between 15 and 30 min. Each horse was fitted with a leg mounted accelerometer...
Sleutjens J, Voorhout G, Van Der Kolk JH, Wijnberg ID, Back W.In dressage, the head and neck position has become an issue of concern as certain extreme positions may imply a welfare risk for the horse. In man, extension and flexion of the cervical spine cause a decrease and increase in intervertebral foramina dimensions, respectively. However, in horses, the influence of flexion and extension on foramina dimensions and its possible interference with peripheral nerve functioning remains unknown. Objective: To determine the effect of ex vivo flexion and extension on intervertebral foramina dimensions in the equine cervical spine. Methods: Computed tomograp...
Ohmura H, Mukai K, Takahashi T, Matsui A, Hiraga A, Jones JH.Accumulated O(2) deficit (AOD) and plasma lactate accumulation rate (PLAR) are alternative methods for estimating net anaerobic energy utilisation (NAEU) in exercising horses. How they compare or their accuracy is unknown. Objective: We hypothesised net anaerobic energy utilisation calculated by PLAR (NAUE(PLAR)) is equivalent to NAUE estimated by AOD (NAUE(AOD)). Methods: Six Thoroughbred horses ran at identical supramaximal speeds (118% aerobic capacity) until exhaustion for 2 runs while breathing normoxic (NO, 21% O(2)) or hyperoxic (HO, 26% O(2)) gas. Jugular blood was sampled at 15 s inte...
Jönsson L, Dalin G, Egenvall A, Näsholm A, Roepstorff L, Philipsson J.Disturbances in skeletal development, primarily osteochondrosis (OC) and palmar/plantar osseous fragments (POF), have been commonly reported as problems in young horses. However, there are few reports of such findings for epidemiological analyses or breeding purposes. Objective: To evaluate equine hospital data as a possible source of information for genetic evaluations by estimating prevalence and heritability of OC in the stifle, hock and fetlock joints and of POF in the fetlock. Methods: Data on Swedish Warmblood (SWB) horses were obtained from a large equine hospital in south Sweden. Preva...
Liburt NR, Adams AA, Betancourt A, Horohov DW, McKeever KH.Studies have demonstrated increases in mRNA expression for inflammatory cytokines following exercise in horses and have suggested those markers of inflammation may play a role in delayed onset muscle soreness. However, measurement of mRNA expression in white blood cells is an indirect method. No studies to date have documented the cytokine response to exercise directly in muscle in horses. Objective: This study tested the hypothesis that exercise increases cytokine markers of inflammation in blood and muscle. Methods: Blood and muscle biopsies were obtained from 4 healthy, unfit Standardbred m...
Thomsen MH, Persson AB, Jensen AT, Sørensen H, Andersen PH.Equine lameness examination is based on subjective visual scoring of lameness. Instrumented objective methods for lameness examinations may be complicated to perform and the equipment is often stationary. Accelerometry has a potential clinical use; however, the reduction and interpretation of equine accelerometric data are not yet routine and the value of accelerometry in equine lameness examination is unclear. Objective: To use accelerometric data to calculate 2 different accelerometric symmetry scores and to evaluate the agreement of these with traditional lameness scores done by experienced...
Haussler KK, Martin CE, Hill AE.Spinal mobilisation and spinal manipulative therapy (SMT) are being applied to horses; however, there are limited objective measures of their effects on spinal mobility or stiffness in actively ridden horses. Objective: To quantify passive spinal movements induced during dorsoventral mobilisation of the trunk and to identify any potential effects of SMT on measures of spinal mobility within the thoracolumbar region in standing horses. We hypothesise that displacement amplitudes will be significantly increased across vertebral levels after SMT, compared to spinal mobilisation only within the co...
Silver IA, Jeffcott LB, Rossdale PD.The British Equine Veterinary Association (BEVA) was established in 1961 and launched the Equine Veterinary Journal (EVJ) in 1968. This review outlines some of the major advances in equine science and practice that have occurred in that time and the role played by the Journal in facilitating those developments.
Nagy A, Murray JK, Dyson S.Endurance is the fastest growing Féderation Équestre International (FEI) discipline and the large number of eliminations on veterinary grounds needs to be investigated. Objective: To document elimination rates and explore potential risk factors for elimination due to lameness or metabolic reasons in 9 countries representing 5 continents. Methods: Data for rides of ≥ 100 km ('elite endurance rides') in Australia, France, Italy, South Africa, Spain, United Arab Emirates (UAE), UK, Uruguay and USA were collected from the FEI website. Data were collected for all started horses on the country, ...
Muñoz A, Riber C, Trigo P, Castejón-Riber C, Castejón FM.Limited information exists concerning the defence of homeostasis during endurance competitions and the relationship with performance. Objective: This research analysed renin (REN), angiotensin II (ANG), aldosterone (ALD) and vasopressin (AVP) in horses covering different distances, assesses differences between successful and eliminated horses and evaluates correlations between hydration status, renal function, electrolytes, REN, ANG, ALD and AVP. Methods: Packed cell volume (PCV), velocity and serum concentrations of REN, ANG, ALD, AVP, Na, K, Cl, Ca, Mg, P, creatine kinase, aspartate aminotra...
Geor RJ, Stewart-Hunt L, McCutcheon LJ.There is limited information about factors regulating glucose utilisation post exercise in horses. Objective: To determine the effects of a single bout of moderate intensity exercise on measures of insulin-mediated (IMGU) and noninsulin-mediated (NIMGU) glucose uptake during a hyperglycaemic clamp (HC). Methods: Hyperglycaemic clamps were administered in random order to 8 Standardbreds under 4 conditions: 1) rest, insulinopenia (R-L); 2) rest, hyperinsulinaemia (R-H); 3) post exercise (45 min at ∼ 50% VO2peak), insulinopenia (Ex-L) and 4) post exercise, hyperinsulinaemia (Ex-H). In the R-L a...
Urschel KL, Geor RJ, Waterfall HL, Shoveller AK, McCutcheon LJ.Providing protein or amino acid mixtures in combination with glucose to post exercise in man has resulted in increases in the post feeding insulin response and in muscle glycogen and protein synthesis rates. However, whether protein and/or amino acids can modify the post exercise insulin responses in horses remains to be fully elucidated. Objective: To determine whether whey protein or leucine addition to a glucose solution affects the post gavage plasma insulin, glucose and amino acid responses in horses and whether these responses are different following a period of exercise vs. rest. Method...
Barnes A, Kingston J, Beetson S, Kuiper C.This study investigated the physiology of endurance horses competing in warm weather over technical terrain, a situation where horses may become metabolically compromised. Objective: There will be changes in physiological, haematological and biochemical variables as horses progress through the 160 km ride and horses detected clinically at the veterinary inspections as metabolically compromised will have significant differences in measured laboratory variables compared to horses that complete the ride successfully. Methods: Forty-eight horses competing in the Australian Tom Quilty 160 km endura...
Trachsel DS, Bitschnau C, Waldern N, Weishaupt MA, Schwarzwald CC.Frequent supraventricular or ventricular arrhythmias during and after exercise are considered pathological in horses. Prevalence of arrhythmias seen in apparently healthy horses is still a matter of debate and may depend on breed, athletic condition and exercise intensity. Objective: To determine intra- and interobserver agreement for detection of arrhythmias at rest, during and after exercise using a telemetric electrocardiography device. Methods: The electrocardiogram (ECG) recordings of 10 healthy Warmblood horses (5 of which had an intracardiac catheter in place) undergoing a standardised ...
Meyer ND, Bayly WM, Sides RH, Wardrop KJ, Slinker BK.Prolonged equine exercise can cause hypochloraemic alkalosis and hypokalaemia secondary to the loss of hypertonic sweat. Movement of ions in and out of erythrocytes during exercise may help regulate acid-base balance and changes in plasma ion concentrations. The extent to which this happens during prolonged equine exercise has not been reported. Objective: To measure changes in blood gases and major plasma and intraerythrocytic (iRBC) ion concentrations of horses undergoing prolonged submaximal exercise. Methods: Six horses were trotted at ∼ 30% VO2max on a treadmill for 105 min. Arterial ((...
McKenzie EC, Garrett RL, Payton ME, Riehl JH, Firshman AM, Valberg SJ.Dantrolene sodium is used to prevent exertional rhabdomyolysis in predisposed horses. Food intake might negatively impact dantrolene bioavailability in horses; however, prolonged feed restriction might be detrimental to performance. Objective: To determine a minimum duration of feed restriction that would optimise plasma dantrolene concentrations in horses after nasogastric administration. It was hypothesised that feed restriction for 4, 8 or 12 h before dantrolene administration would result in higher plasma dantrolene concentrations than achieved with no feed restriction before treatment. Me...
Barrey E.Equine breeding selection has been developed by applying quantitative genetic methods for calculating the heritability of the complex traits such as performance in racing or sport competitions. With the great development of biotechnologies, equine molecular genetics has come of age. The recent sequencing of the equine genome by an international consortium was a major advance that will impact equine genomics in the near future. With the rapid progress in equine genetics, new applications in early performance evaluation and the detection of disease markers become available. Many new biomolecular...
Kemmink A, Westermann CM, van der Kolk JH.The quantity of glucose disposal during exercise (walk and trot) compared to rest by use of the hyperglycaemic clamp technique has not been reported previously and has relevance to nutritional requirements. Objective: Exercise (walk and trot) significantly increases glucose disposal compared to rest. Methods: Seven healthy Dutch Warmblood mares, all in dioestrus, mean ± s.d. age 11.6 ± 2.4 years and weighing 569 ± 40 kg were fasted for 12 h prior to a hyperglycaemic clamp at rest (maintaining a steady state of the blood glucose concentration during 30 min), walk (10 min, 1.5 m/s), trot (20 ...
Byström A, Stalfelt A, Egenvall A, Von Peinen K, Morgan K, Roepstorff L.Saddle fit is well recognised as an important factor for the health and performance of riding horses. However, only few studies have addressed general effects of different saddle construction details within a group of horses. Objective: To assess the influence of girth strap placement, traditional vs. v-system, and panel flocking material, wool vs. synthetic foam, on the saddle pressure pattern during riding. Methods: Six horses were ridden by 3 riders in sitting and rising trot and sitting canter. Saddle pressure was measured with 3 different saddle variants: 1) wool flocked panels and tradit...
Hill C, Crook T.Massage is widely used in physiotherapy, but there has been little previous research examining its effectiveness in increasing equine soft tissue length. Objective: To determine the effect of massage on equine hindlimb protraction. We hypothesised that massage to the caudal muscles of the equine hindlimb, specifically the superficial gluteal, semitendinosus, biceps femoris and semimembranosus muscles, can increase passive and active hindlimb protraction. Methods: The study used a crossover design in which 8 horses were randomly assigned to 2 groups of 4, A and B. Group A received massage for 3...
Lawson SE, Marlin DJ.The function of the forelimb is fundamental to understanding both sound and pathological locomotion. The precise movements of the equine shoulder are hidden by layers of skin and muscle and hence the shoulder is normally modelled as a simple pivot during locomotion which assumes that any translational motion is negligible. Objective: To record and quantify the sliding motion of the scapula during locomotion, using a novel imaging technique. Methods: Scapula motion during locomotion in the horse was calculated by tracking the ripple of the shoulder blade's movement under an array of markers pla...
Ramseyer A, Sides R, Slinker B, Evans D, Bayly W.The ability to obtain breath-by-breath measures of ventilatory mechanics for the entirety of an exercise test, regardless of speed(s) or duration enables evaluations of equine ventilation during exercise that are necessary for assessments of performance. Objective: Evaluation of a new ergospirometer (Quadflow; QF) system's accuracy and repeatability for measuring pulmonary variables in contrast to the established pneumotachometer-based system (control) and assessment of its effects, if any, on exercise capacity at high speeds. Methods: Five Thoroughbred horses each performed 10 incremental exe...
Allen KJ, Franklin SH.Overground endoscopy is being performed with increasing frequency in the UK. A previous study has shown that the type of exercise test may affect the diagnosis of upper respiratory tract (URT) obstructions. The successful clinical application of overground endoscopy systems requires understanding of appropriate field exercise testing protocols. Objective: The aim of this study was to report the exercise test parameters used during overground endoscopy in UK Thoroughbred racehorses and to investigate potential effects of these on the diagnosis of URT obstructions. Methods: The exercise test par...
Warner SM, Koch TO, Pfau T.Assessing back movement is an important part of clinical examination in the horse and objective assessment tools allow for evaluating success of treatment. Objective: Accuracy and consistency of inertial sensor measurements for quantification of back movement and movement symmetry during over ground locomotion were assessed; sensor measurements were compared to optical motion capture (mocap) and consistency of measurements focusing on movement symmetry was measured. Methods: Six nonlame horses were trotted in hand with synchronised mocap and inertial sensor data collection (landmarks: T6, T10,...
Latif SN, Von Peinen K, Wiestner T, Bitschnau C, Renk B, Weishaupt MA.To a large extent the success of a racehorse depends on effective and health preserving training methods. An important issue is the prevention of back pain. The influence of different types of training saddles (normal tree: S(A), treeless: S(B), flexible tree: S(C)) on the saddle pressure patterns in racehorses have not previously been investigated. It is commonly assumed that S(A) limits the motion of the back especially in the lower thoracic region during gallop. Objective: S(A) produces higher pressures in the caudal part of the saddle at trot (rising trot), canter and gallop (both in a joc...
von Peinen K, Wiestner T, von Rechenberg B, Weishaupt MA.Similar to human decubitus ulcers, local high pressure points from ill-fitting saddles induce perfusion disturbances of different degrees resulting in tissue hypoxia and alteration in sweat production. Objective: To relate the different clinical manifestations of saddle sores to the magnitude of saddle pressures at the location of the withers. Methods: Sixteen horses with dry spots after exercise (Group A) and 7 cases presented with acute clinical signs of saddle pressure in the withers area (Group B) were compared with a control group of 16 sound horses with well fitting saddles (Group C). Al...
Sloet van Oldruitenborgh-Oosterbaan MM, Genzel W, van Weeren PR.Welfare concerns over the reasons for interruption or termination of a sporting career in horses have been expressed. Objective: To study the career of competition horses and factors that influence career length. Methods: In 2004, 46,576 rider-horse combinations were registered with the Dutch National Equestrian Federation (KNHS) in dressage, show jumping, eventing and endurance. From this population, approximately 1% of horses in each discipline were selected at random and all recorded competition data from the KNHS registration system collected and supplemented by detailed rider/owner teleph...
Finno CJ, McKenzie E, Valberg SJ, Pagan J.Recurrent exertional rhabdomyolysis (RER) occurs in fit, nervous Thoroughbreds fed high nonstructural carbohydrate (NSC) diets. Clinical signs are diminished by feeding low NSC, high fat diets; however, the mechanism is unclear. Objective: To determine if the glucose, insulin and cortisol response to isocaloric diets varying in fat and NSC availability differ in fit vs. unfit Thoroughbreds with RER. Methods: Four fit (10 weeks treadmill training) RER Thoroughbred mares were exercised and fed 3 isocaloric (121 MJ/day) diets in a 5 day/diet block design. Two high NSC concentrates, sweet feed (SF...
Axon JE, Carrick JB, Barton MD, Collins NM, Russell CM, Kiehne J, Coombs G.To evaluate if methicillin-resistant Staphylococcus aureus (MRSA) is present in the horse population in Australia. Methods: A two-part retrospective study of laboratory submissions of microbial culture results from horses. Methods: Part A: medical records of 216 horses that had MRSA screening performed on nasal swabs collected over a 30-day period at admission to the Scone Equine Hospital Clovelly Intensive Care Unit were retrieved. Part B: laboratory records from 2004 to 2009 of culture submissions to the Scone Veterinary Laboratory were reviewed and cultures that grew MRSA were identified. T...
Limone LE, Baratt RM.This step-by-step article describes radiographic imaging of the horse's teeth and paranasal sinuses with standard radiographic equipment. Obtaining radiographs of the horse's skull that are of diagnostic quality can be challenging. The descriptions offered in this article can help practitioners become more comfortable with obtaining diagnostic images, which will improve recognition of radiographic signs of dental and paradental pathology.
Roberts MC, Pinsent PJ.Three horses suffering from malabsorption were shown to have alimentary lymphosarcoma predominantly affecting the small intestine and the associated lymph nodes. The diffuse cellular infiltration in two of the case produced marked changes in the villous architecture reducing the available mucosal surface area, and, with lowered or barely detectable disaccharidase activities, contributed to the impairment of digestive-absorptive processes. One of the horses maintained a voracious appetite and was not diarrhoeic, but failed to gain weight, indicating differences in the production and utilisation...
Murray DR, Ladds PW, Johnson RH, Pott BW.Extensive subcutaneous phycomycosis of the lower hindlimb developed over a period of 8 months in a Thoroughbred filly. There was no response to treatments such as trichlorphon, sodium iodide, or etisazole. Extension of the limb lesion over the following 3 months was associated with an enlarged inguinal lymph node, which was removed. Characteristic phycomycotic lesions were observed in the node, and a fungus having the morphologic features of Hyphomyces destruens was isolated from both the limb and nodal lesions.
Hood DM.Many of the difficulties in managing the horse with chronic laminitis are associated with the foot's mechanical failure. The occurrence of digital collapse cannot be viewed in isolation as the primary therapeutic focus. The circulatory, metabolic, and growth pattern changes induced by the foot's mechanical collapse often serve as major limiting factors to successful rehabilitation. From the discussion above, it is obvious that a significant amount of research is needed to better understand the biomechanical pathologies of the failed foot.
Major DA.This paper describes a protocol for hygiene practices that was devised by a practice in which all veterinarians were involved on a daily basis in visiting infected premises, including sampling, treatment of clinical cases and general veterinary work. This protocol was strictly followed when attending an infected or at risk property.
Gygax D, Fürst A, Picek S, Kummer M.To report internal fixation of a fractured axis with a dynamic compression plate (DCP). Methods: Case report. Methods: A 7-year-old Warmblood gelding. Methods: Surgery was performed under anesthesia in sternal recumbency. After fracture reduction the complete transverse fracture in the cranial third of the axis was stabilized with a 7-hole 4.5 mm DCP. Optimal positioning of the plate and the length of the screws were facilitated by fluoroscopy. Recovery from anesthesia was supervised in a pool. Results: The horse had an excellent outcome and returned to its previous activity level. Conclusions...
Robinson KA, Manning ST.This report describes a primiparous 8-year-old Morgan mare, which displayed premature lactation that began at approximately 240 d of gestation and lasted approximately 4 wk. The premature lactation resolved spontaneously, and the pregnancy was subsequently carried to full term with the delivery of a live foal and a mummified fetus. Lactation prématurée et rétention d’un fœtus momifié avec naissance vivante du jumeau chez une jument Morgan primipare. Ce rapport décrit une jument Morgan primipare âgée de 8 ans, qui a manifesté une lactation prématurée qui a commencé vers 240 jours ...
Ishii H, Shibuya M, Leung GN, Nozawa S, Yamashita S, Yamada M, Kushiro A, Kasashima Y, Okada J, Kawasaki K, Kijima-Suda I.GW1516 is a peroxisome proliferator-activated receptor-δ (PPAR-δ) agonist that is banned in horseracing and equestrian sports. Long-term detection and longitudinal distribution of GW1516 in the mane of a horse are reported for the first time and this hair analysis could prolong the detection window of GW1516 for doping control. Methods: Mane hairs were divided into three segments (0-7, 7-15, and >15 cm from the cut end) and completely pulverized and homogenized for analysis. The pulverized hair samples were extracted with methanol followed by further purification and the extracts were a...
Baker D, Kreeger J.An expansile, yellow, soft mass was observed in the free wall of the right ventricle of a 3-year-old, male, Morgan, horse at necropsy. The mass was composed of well differentiated adipocytes in solid sheets or infiltrating between muscle fibers with associated myofiber degeneration. The mass was interpreted to be an infiltrative lipoma of the heart.
Kološ F, Bodeček Š, Žert Z.To describe and report preliminary outcomes of a contralateral trans-nasal endoscopic laser fenestration of the conchae for endoscopic examination and treatment of paranasal sinuses in horses. Methods: Cadaveric experimental and prospective clinical study. Methods: Normal cadaveric equine heads (n = 7) and equine patients (horses n = 7, donkey n = 1) diagnosed with sinusitis. Methods: Ex vivo: a video-endoscope containing a diode laser fiber in the working canal was passed through the nostril and retroflexed in the nasopharynx toward the contralateral conchae. Ventral or dorsal con...
Uldahl M, Bundgaard L, Dahl J, Clayton HM.This study addresses the presence and location of oral lesions in 342 dressage, show jumping, and eventing horses examined at an obligatory veterinary inspection before competing in the Danish National Championship in 2020. Ulcers in the lip commissures were photographed for subsequent pathological analysis. If a lesion was found at the lip commissures on one side, there was an increased risk of finding a similar lesion on the other side (ulcer: p < 0.0001; scarring/depigmentation: p < 0.0001; fissure: p = 0.002; erosion/contusion: p < 0.0001). At the lip commissures, external (cutaneous) ulce...
Wierup M, DiPietro JA.The fecal flora of 56 clinically healthy and 23 sick horses were examined bacteriologically for counts of Clostridium perfringens, molds, coliforms, alpha- and beta-hemolytic streptococci, and microbes belonging to genus Bacillus, as well as for the presence of Salmonella spp. Of the healthy horses, 85.7% had a C perfringens count less than 10(1) colony-forming units/g of feces. Of the healthy horses, lowest counts were found in race-horses. Of the sick horses, equine intestinal clostridiosis was diagnosed in 2 horses with large C perfringens counts (10(4) to 10(7) colony-forming units/g) and ...
Haussler KK, Stover SM.Thirty-six Thoroughbred racehorses that died at California racetracks between October 1993 and July 1994 were evaluated for stress fractures in the caudal portion of the thoracic and lumbosacral regions of the spine and the pelvis. The lumbosacral spine and pelvis were collected, debrided of soft tissues and examined visually for the presence of an incomplete fracture line and focal periosteal proliferation, characteristic of a stress fracture. Sixty-one per cent of specimens had evidence of stress fracture in the caudal portion of the thoracic and lumbosacral regions of the spine and the pelv...
Ginther OJ.Fixation and orientation of the conceptus within the uterine lumen of 40 barren mares were examined by ultrasound daily on days 11-21 and at three-day intervals thereafter until day 48. The growth curve of the in situ conceptus had a distinct plateau between days 17-24, as determined by measurements of the width and area of conceptuses on the ultrasound images. The vesicle expanded at an average daily rate of 3-4 mm before the plateau and 2-3 mm after the plateau. Dramatic changes occurred in the shape of conceptus. The predominant shapes were approximately as follows: days 11-16, spherical; d...
Olsén L, Bremer H, Olofsson K, Bröjer J, Bondesson U, Bergh A, Nostell K, Broström H, Bengtsson B, Ingvast-Larsson C.The aim was to supply information about the possibility of replacing the procaine salt with the sodium salt for benzylpenicillin IM treatment in horse in order to diminish the risk for procaine adverse effects. In a crossover study eight horses were given 15 mg/kg sodium benzylpenicillin (Na-pc) twice daily or procaine benzylpenicillin (control) once daily IM for four days. The half-life of Na-pc was 1.9h, peak concentration was 14,600 ng/mL reached after about 23 min. Trough plasma concentration was 281 ng/mL and protein binding 62.8%. The fT>MIC for Staphylococcus aureus was 63% and 100% for...
Pasolini MP, Spinella G, Del Prete C, Valentini S, Coluccia P, Auletta L, Greco M, Meomartino L.Ultrasonography (US) is the recommended imaging technique to evaluate jugular veins. This prospective randomized clinical study was designed to collect a series of B-mode US measurements of manually distended jugular veins in healthy Italian Standardbreds and to find possible correlations between ultrasound measurements and animal morphometric characteristics. Forty-two horses, eight males and 34 females (range 3-22 years; bodyweight 494.4 ± 41.7 kg), were included in the study. The diameters and wall thicknesses of both jugular veins were measured at three different sites of the neck...
McMullen RJ, Clode AB, Pandiri AK, Malarkey DE, Michau TM, Gilger BC.A case of epibulbar melanoma in a 6-month-old, gelded, chestnut Hanoverian foal is reported. The location and clinical appearance upon initial presentation led to the tentative diagnosis of staphyloma or a congenital mass of unknown origin. An attempt was made to surgically excise the mass under general anesthesia, but due to its infiltrative nature and intraoperative appearance, most, but not all was removed without compromising the integrity of the globe. Histopathological evaluation revealed a multinodular to packeted, poorly demarcated, unencapsulated, infiltrative exophytic melanocytic ne...
Solís-Hernández D, Saucedo-Gutiérrez KL, Meza-Lucas A, Gómez-de-Anda FR, Medina-Lerena MS, García-Rodea R, Corona-Souza MT, Pérez-Ramírez MÁ....This work aimed to investigate the prevalence of Trichinella infection in horses (Equus ferus caballus) handled by rural slaughterhouses across five distinctive socioeconomic regions in Mexico. Serum samples were obtained by non-probabilistic convenience sampling in the Eastern, Southern Central and Western regions (100 samples of each). Additionally, muscle tissue samples were collected from the East (n=45), Southeastern (n=88), Southern Central (n=39) and Southwestern (n=11) regions. Antibodies were determined by Western blot and the muscle tissue was examined by artificial digestion. A glob...
Pearson H, Pinsent PJ, Polley LR, Waterman A.Four cases of fatal diaphragmatic rupture in the horse are described. In 2 cases there was no history of injury but the other 2 animals had sustained recent thoracic trauma. Three of the horses had signs of colic and bowel obstruction complicated, in 2 cases, by respiratory embarrassment; the fourth died rapidly, presumably of shock. Previously published cases are reviewed and the causes, clinical effects, diagnosis and treatment of the disorder are discussed.