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Topic:Veterinary Medicine

Veterinary medicine for horses encompasses the study and application of medical practices to diagnose, treat, and prevent diseases in equine species. This field involves a comprehensive understanding of equine anatomy, physiology, pathology, and pharmacology. Veterinary practitioners employ a range of diagnostic tools and therapeutic interventions to address health issues in horses, including lameness, gastrointestinal disorders, respiratory conditions, and infectious diseases. Preventative care, such as vaccination and deworming programs, is also a significant aspect of equine veterinary medicine. This page gathers peer-reviewed research studies and scholarly articles that explore various aspects of veterinary medicine as it pertains to horses, including advancements in diagnostic techniques, treatment protocols, and preventive health strategies.
Pharmacokinetics and therapeutic efficacy of rimantadine in horses experimentally infected with influenza virus A2.
American journal of veterinary research    July 17, 1999   Volume 60, Issue 7 888-894 
Rees WA, Harkins JD, Lu M, Holland RE, Lehner AF, Tobin T, Chambers TM.To determine pharmacokinetics of single and multiple doses of rimantadine hydrochloride in horses and to evaluate prophylactic efficacy of rimantadine in influenza virus-infected horses. Methods: 5 clinically normal horses and 8 horses seronegative to influenza A. Methods: Horses were given rimantadine (7 mg/kg of body weight, i.v., once; 15 mg/kg, p.o., once; 30 mg/kg, p.o., once; and 30 mg/kg, p.o., q 12 h for 4 days) to determine disposition kinetics. Efficacy in induced infections was determined in horses seronegative to influenza virus A2. Rimantadine was administered (30 mg/kg, p.o., q 1...
In vitro allergen-induced degranulation of pulmonary mast cells from horses with recurrent airway obstruction (heaves).
American journal of veterinary research    July 17, 1999   Volume 60, Issue 7 841-847 
Hare JE, Viel L, Conlon PD, Marshall JS.To determine the capacity of pulmonary mast cells (PMC) to degranulate in response to various potential allergens and other secretagogues in horses with recurrent airway obstruction (heaves) and clinically normal horses before and after exposure to moldy hay. Methods: 5 horses with heaves and 5 clinically normal horses. Methods: Heaves was characterized as an increased clinical respiratory score and maximum change in transpulmonary pressure of > 20 cm H2O after exposure. Bronchoalveolar lavage was performed during each period. Washed and resuspended cells were exposed for 20 minutes at 37 C wi...
Myeloperoxidase activity of the large intestine in an equine model of acute colitis.
American journal of veterinary research    July 17, 1999   Volume 60, Issue 7 807-813 
McConnico RS, Weinstock D, Poston ME, Roberts MC.To determine whether quantification of myeloperoxidase (MPO) activity could be a useful laboratory technique to detect granulocyte infiltration in equine intestinal tissues. Methods: Intestinal tissue (inflamed or healthy) collected from 16 age- and sex-matched Shetland Ponies. Methods: Intestinal tissue MPO activity was determined, and histologic assessment of adjacent specimens from healthy and inflamed intestine was done. Results: Intestinal tissue MPO activity and histopathologic score increased with time after castor oil challenge and peaked at 16 hours in an equine diarrhea model in whic...
Equine arteritis virus derived from an infectious cDNA clone is attenuated and genetically stable in infected stallions.
Virology    July 16, 1999   Volume 260, Issue 1 201-208 doi: 10.1006/viro.1999.9817
Balasuriya UB, Snijder EJ, van Dinten LC, Heidner HW, Wilson WD, Hedges JF, Hullinger PJ, MacLachlan NJ.Virus derived from an infectious cDNA clone of equine arteritis virus (EAV030H) was intranasally inoculated into two stallions, neither of which subsequently developed clinical manifestations of equine viral arteritis (EVA). Virus was isolated from nasal swabs and mononuclear cells collected from both stallions
Galloping to the defence of other species. Burgener L.No abstract available
Malignant rhabdoid tumour in the orbit of a horse.
Journal of comparative pathology    July 16, 1999   Volume 121, Issue 2 197-201 doi: 10.1053/jcpa.1999.0311
Hong CB, Van Meter PW, Latimer CL.A malignant rhabdoid tumour was diagnosed in the orbit of a 2-year-old Thoroughbred filly. The neoplasm, which was very aggressive, was present in nearly every part of the ocular and periocular structures and had spread to the lymph nodes of the head and neck, the salivary glands and the subcutaneous tissues around the eye. The neoplasm was composed of polygonal cells with abundant eosinophilic cytoplasm. Many cells had a large, vesiculate, indented nucleus and contained a paranuclear globular inclusion. Ultrastructurally, the inclusions were seen to consist of whorls of intermediate filaments...
Diagnosis of larval cyathostominosis in horses in Belgium.
The Veterinary record    July 15, 1999   Volume 144, Issue 24 665-668 doi: 10.1136/vr.144.24.665
Smets K, Shaw DJ, Deprez P, Vercruysse J.Between October 1996 and May 1997, 94 horses which were suspected of being infected with strongyles were examined clinically, and samples of faeces were examined for strongyle eggs and cyathostome larvae (L4) and adults. Blood samples were monitored for total protein, albumin and beta-globulins. In 28 of the horses (30 per cent) cyathostome L4 and adults were detected in the faeces, and were significantly associated with the horses' condition, the occurrence of diarrhoea, with lower concentrations of total protein and albumin, and with higher percentages of beta-globulin. Thirty-four of the ho...
Pilot study to investigate the efficacy of a 1 per cent selenium sulphide shampoo in the treatment of equine chorioptic mange.
The Veterinary record    July 15, 1999   Volume 144, Issue 24 674-675 doi: 10.1136/vr.144.24.674
Curtis CF.No abstract available
Antibody responses to DNA vaccination of horses using the influenza virus hemagglutinin gene.
Vaccine    July 14, 1999   Volume 17, Issue 18 2245-2258 doi: 10.1016/s0264-410x(98)00496-4
Lunn DP, Soboll G, Schram BR, Quass J, McGregor MW, Drape RJ, Macklin MD, McCabe DE, Swain WF, Olsen CW.Equine influenza virus infection remains one of the most important infectious diseases of the horse, yet current vaccines offer only limited protection. The equine immune response to natural influenza virus infection results in long-term protective immunity, and is characterized by mucosal IgA and serum IgGa and IgGb antibody responses. DNA vaccination offers a radical alternative to conventional vaccines, with the potential to generate the same protective immune responses seen following viral infection. Antigen-specific antibody isotype responses in serum and mucosal secretions were studied i...
Serum cortisol concentrations in response to incremental doses of inhaled beclomethasone dipropionate.
Equine veterinary journal    July 13, 1999   Volume 31, Issue 3 258-261 doi: 10.1111/j.2042-3306.1999.tb03183.x
Rush BR, Trevino IC, Matson CJ, Hakala JE.No abstract available
Ultrasonographic anatomy of the accessory ligament of the superficial digital flexor tendon in horses.
Equine veterinary journal    July 13, 1999   Volume 31, Issue 3 186-191 doi: 10.1111/j.2042-3306.1999.tb03170.x
Denoix JM, Busoni V.The ultrasonographic anatomy of the accessory ligament of the superficial digital flexor tendon (AL-SDFT) in the horse is presented. Comparison between anatomical sections of isolated limbs and ultrasound scans of the distal antebrachium in sound horses enabled the authors to establish the normal reference ultrasonographic images of this structure. The AL-SDFT inserts 7-14 cm above the antebrachiocarpal joint on the palmaromedial aspect of the radius. Ultrasonographically it appears as an uniformly echogenic structure located deep to the median artery. The knowledge of ultrasonographic anatomy...
Results of screw fixation combined with cortical drilling for treatment of dorsal cortical stress fractures of the third metacarpal bone in 56 Thoroughbred racehorses.
Equine veterinary journal    July 13, 1999   Volume 31, Issue 3 252-257 
Dallap BL, Bramlage LR, Embertson RM.The purpose of this study was to evaluate screw fixation with cortical drilling as a surgical treatment for dorsal cortical stress fractures of MCIII in the Thoroughbred racehorse. Details of age, sex, limb affected, fracture assessment, and post operative recommendations were obtained from medical records and radiographs. Fracture healing was assessed radiographically at the time of screw removal. Performance evaluation was determined from race records obtained from The Jockey Club Information System, Lexington, Kentucky. Fifty-six Thoroughbred racehorses were treated surgically for stress fr...
The role of prostanoids and nitric oxide in endotoxin-induced hyporesponsiveness of equine digital blood vessels.
Equine veterinary journal    July 13, 1999   Volume 31, Issue 3 212-218 doi: 10.1111/j.2042-3306.1999.tb03175.x
Bailey SR, Elliott J.Endotoxin has been implicated in the pathophysiology of acute laminitis. The aim of this study was to examine the direct effects of endotoxin on isolated equine digital blood vessels. Equine digital veins (EDV), incubated in Krebs-Henseleit solution containing lipopolysaccharide (LPS) (1 microg/ml) became hyporesponsive to 5-HT after 16 h. Cycloheximide and ibuprofen blocked this effect of LPS and increased the maximum response obtained to 5-HT when compared to control vessels. L-nitroarginine methyl ester (L-NAME) reversed the hyporesponsiveness caused by LPS. Vessels maintained in culture me...
Endoscopic examination of the tarsal sheath of the lateral digital flexor tendon in horses.
Equine veterinary journal    July 13, 1999   Volume 31, Issue 3 219-227 doi: 10.1111/j.2042-3306.1999.tb03176.x
Cauvin ER, Tapprest J, Munroe GA, May SA, Schramme MC.This study was designed to develop a reliable technique for endoscopic examination of the tarsal sheath of the lateral digital flexor tendon of horses. The anatomy of the tendon sheath and associated structures was studied in detail in cadavers before determining portals for the insertion of an arthroscope into the sheath. Approaches into the sheath through the proximal pouch and through the flexor retinaculum, at the level of the sustentaculum tali, were performed and compared in cadavers. The proximal pouch portal permitted visualisation only of the proximal half of the sheath, while the app...
Assessment of bilateral infra-orbital nerve blockade and bilateral infra-orbital neurectomy in the investigation and treatment of idiopathic headshaking.
Equine veterinary journal    July 13, 1999   Volume 31, Issue 3 262-264 doi: 10.1111/j.2042-3306.1999.tb03184.x
Mair TS.No abstract available
Distribution of substance P binding sites in equine airways.
Equine veterinary journal    July 13, 1999   Volume 31, Issue 3 238-242 doi: 10.1111/j.2042-3306.1999.tb03179.x
Sonea IM, Bowker RM, Robinson NE.Autoradiography with [125I]-Bolton Hunter substance P ([I]-BHSP) was used to detect substance P binding sites in the equine lung. Specific [I]-BHSP binding sites were very dense over small bronchial vessels, tracheobronchial glands and airway epithelium in large and small airways. The density of [I]-BHSP binding sites over airway smooth muscle was much lower than in the preceding tissues. Competition with an excess of either a specific neurokinin 1 receptor agonist, or a specific neurokinin 2 receptor agonist indicated that most specific [I]-BHSP binding sites in the equine lung represent neur...
The science and art of angular limb deformity correction.
Equine veterinary journal    July 13, 1999   Volume 31, Issue 3 182-183 doi: 10.1111/j.2042-3306.1999.tb03168.x
Bramlage LR.No abstract available
Prediction of first season stallion fertility of 3-year-old Dutch Warmbloods with prebreeding assessment of percentage of morphologically normal live sperm.
Equine veterinary journal    July 13, 1999   Volume 31, Issue 3 248-251 doi: 10.1111/j.2042-3306.1999.tb03181.x
Parlevliet JM, Colenbrander B.In the selection procedure to acquire a breeding licence, 3-year-old Dutch Warmblood stallions have to undergo a breeding soundness test It is questioned whether this evaluation is predictive of the stallion's fertility results in the first breeding season. Therefore, semen parameters at the beginning of their first breeding season were evaluated and correlated to nonreturn at first cycle and foaling rate of mares bred by stallions (n = 13). The total number of mares inseminated with chilled semen from those stallions was 1055. Semen parameters were recorded on 2 ejaculates, collected 1 h apar...
Dystocia and caesarean sections: the importance of duration and good judgement.
Equine veterinary journal    July 13, 1999   Volume 31, Issue 3 179-180 doi: 10.1111/j.2042-3306.1999.tb03167.x
Embertson RM.No abstract available
Physeal growth retardation leads to correction of intracarpal angular deviations as well as physeal valgus deformity.
Equine veterinary journal    July 13, 1999   Volume 31, Issue 3 193-196 doi: 10.1111/j.2042-3306.1999.tb03171.x
Brauer TS, Booth TS, Riedesel E.Retrospective analysis of the radiographs of horses with carpal valgus, presented to the Iowa State University Veterinary Teaching Hospital from 1987-1996, were used to compare 2 methods of geometric analysis for finding the total angle of deviation. The pivot point angle method and the individual joint angle method were found to be comparable for determining the total angle of deviation. The individual joint angle method was used to analyse individual carpal joint angles and physis angle in joints with carpal valgus, as well as the changes that occurred in response to surgical correction. Mul...
New treatment technologies demand rigorous evaluation.
Equine veterinary journal    July 13, 1999   Volume 31, Issue 3 184 doi: 10.1111/j.2042-3306.1999.tb03169.x
Kaneps AJ.No abstract available
Comparison of bacteriology and cytology of tracheal fluid samples collected by percutaneous transtracheal aspiration or via an endoscope using a plugged, guarded catheter.
Equine veterinary journal    July 13, 1999   Volume 31, Issue 3 197-202 doi: 10.1111/j.2042-3306.1999.tb03172.x
Christley RM, Hodgson DR, Rose RJ, Reid SW, Hodgson JL.Cytological and bacteriological results from tracheal fluid samples obtained endoscopically using a telescoping, plugged catheter (TPC) were compared with results from samples collected by percutaneous transtracheal aspiration (PTA). The TPC technique and PTA were performed in random order on 9 healthy Standardbred geldings. Three weeks later the procedures were performed on the same horses in the reverse order. The presence of oropharyngeal contamination was determined by quantitative bacteriology and quantification of squamous epithelial cells (SEC)/ml sample. The relative numbers of macroph...
In vitro interactions of cryopreserved stallion spermatozoa and oviduct (uterine tube) epithelial cells or their secretory products.
Animal reproduction science    July 13, 1999   Volume 56, Issue 1 51-65 doi: 10.1016/s0378-4320(99)00030-5
Ellington JE, Samper JC, Jones AE, Oliver SA, Burnett KM, Wright RW.Formation of a spermatozoa ('sperm') reservoir in the mare is thought to occur through lectin-mediated sperm attachment to the oviductal epithelium. Once attached, prefertilization sperm survival is supported by oviductal factors. Cryopreservation of stallion sperm decreases the number of sperm attaching to oviduct epithelial cells (OEC) and the length of time these sperm survive. Quantification of in vitro interactions between sperm and OEC in a co-culture system may provide an assay for functional integrity of cryopreserved or fresh sperm samples. Additionally, superior additives for in vitr...
Caesarean section and other methods for assisted delivery: comparison of effects on mare mortality and complications.
Equine veterinary journal    July 13, 1999   Volume 31, Issue 3 203-207 doi: 10.1111/j.2042-3306.1999.tb03173.x
Freeman DE, Hungerford LL, Schaeffer D, Lock TF, Sertich PL, Baker GJ, Vaala WE, Johnston JK.Data from 116 mares that had caesarean section or vaginal delivery at 2 university hospitals were analysed in 5 groups, as follows: dystocia corrected by caesarean section, Group DCS (n = 48); elective caesarean section, Group ECS (n = 10); caesarean section concurrently with colic surgery, Group CCS (n = 8); assisted vaginal delivery, Group AVD (n = 22); and controlled vaginal delivery under general anaesthesia, Group CVD (n = 28). Survival rate in all mares that had caesarean section, excluding Group CCS, was 88% (51/58). All mares in Group ECS survived and Group CCS had the lowest survival ...
Expression of endothelin in equine laminitis.
Equine veterinary journal    July 13, 1999   Volume 31, Issue 3 243-247 doi: 10.1111/j.2042-3306.1999.tb03180.x
Katwa LC, Johnson PJ, Ganjam VK, Kreeger JM, Messer NT.Biosynthesis of endothelin-1 (ET-1), the most potent endogenous vasoconstrictor yet identified, is increased following myocardial infarction (MI) in man. Pathological events which occur in the connective tissues of the equine hoof during laminitis are similar in some respects, to changes occurring in the myocardial connective tissues following MI in man. The objective of this study was to determine whether ET-1 expression in connective tissues obtained from the hoof of laminitic horses is increased compared with tissues obtained from healthy horses. Expression of ET-1 in connective tissues of ...
The effect of low level laser therapy (LLLT) on wound healing in horses.
Equine veterinary journal    July 13, 1999   Volume 31, Issue 3 228-231 doi: 10.1111/j.2042-3306.1999.tb03177.x
Petersen SL, Botes C, Olivier A, Guthrie AJ.Laser therapy is used in many countries, including South Africa, for the treatment of skin wounds. Low level galium aluminium arsenide (GaAlAs) laser was administered to full thickness skin wounds (3 x 3 cm) induced surgically on the dorsal aspect of the metacarpophalangeal joints of 6 crossbred horses in a randomised, blind, controlled study. Treated wounds that received a daily laser dosage of 2 J/cm2 were compared with nontreated control wounds on the opposite leg. There were no wound complications. Both groups of wounds were cleaned daily using tap water. Wound contraction and epithelialis...
[Acute blindness as the consequence of trauma in a Welsh pony foal].
Tijdschrift voor diergeneeskunde    July 10, 1999   Volume 124, Issue 12 383 
van den Brink G.No abstract available
Efficacy of a commercial vaccine for preventing disease caused by influenza virus infection in horses.
Journal of the American Veterinary Medical Association    July 9, 1999   Volume 215, Issue 1 61-66 
Morley PS, Townsend HG, Bogdan JR, Haines DM.To evaluate efficacy of a commercial vaccine for prevention of infectious upper respiratory tract disease (IURD) caused by equine influenza virus. Methods: Double-masked, randomized, controlled field trial. Methods: 462 horses stabled at a Thoroughbred racetrack. Methods: Vaccine or saline solution placebo was administered 4 times in the population at 6-week intervals. The vaccine contained 3 strains of inactivated influenza virus, and inactivated equine herpesvirus type 4. Horses received 1 or 2 doses of vaccine or placebo prior to onset of a natural influenza epidemic, and were examined 5 d/...
Effects of blood contamination of cerebrospinal fluid on western blot analysis for detection of antibodies against Sarcocystis neurona and on albumin quotient and immunoglobulin G index in horses.
Journal of the American Veterinary Medical Association    July 9, 1999   Volume 215, Issue 1 67-71 
Miller MM, Sweeney CR, Russell GE, Sheetz RM, Morrow JK.To determine effects of blood contamination on western blot (WB) analysis of CSF samples for detection of anti-Sarcocystis neurona antibodies, and on CSF albumin and IgG concentrations, albumin quotient (AQ), and IgG index in horses. Methods: Prospective in vitro study. Methods: Blood with various degrees of immunoreactivity against S neurona was collected from 12 healthy horses. Cerebrospinal fluid without immunoreactivity against S neurona was harvested from 4 recently euthanatized horses. Methods: Blood was serially diluted with pooled nonimmunoreactive CSF so that final dilutions correspon...
A comparison of the bioequivalence of 0.5% fenbendazole top dress pellets or 10% fenbendazole oral suspension against a spectrum of equine parasites.
Veterinary parasitology    July 7, 1999   Volume 83, Issue 1 79-85 doi: 10.1016/s0304-4017(99)00041-2
Hutchens DE, Paul AJ, DiPietro JA, Lock TF, Jones CJ, Rowley DD, Wallace RW.A controlled test was conducted to assess the efficacy bioequivalence of a single dose of 0.5% fenbendazole (FBZ) top dress pellets to a 10% FBZ suspension formulation (Panacur suspension 10%, Hoechst Roussel Vet). Thirty horses with naturally-acquired parasite infections, in replicates of three, were used. Strongyle egg per gram counts were not significantly different (P>0.1) between groups pretreatment, but FBZ treated groups were significantly different from the control group post-treatment. At necropsy, which occurred seven to nine days post-treatment, two methods of nematode recovery were...