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Topic:Veterinary Medicine

Veterinary medicine for horses encompasses the study and application of medical practices to diagnose, treat, and prevent diseases in equine species. This field involves a comprehensive understanding of equine anatomy, physiology, pathology, and pharmacology. Veterinary practitioners employ a range of diagnostic tools and therapeutic interventions to address health issues in horses, including lameness, gastrointestinal disorders, respiratory conditions, and infectious diseases. Preventative care, such as vaccination and deworming programs, is also a significant aspect of equine veterinary medicine. This page gathers peer-reviewed research studies and scholarly articles that explore various aspects of veterinary medicine as it pertains to horses, including advancements in diagnostic techniques, treatment protocols, and preventive health strategies.
Glomerular filtration rate, effective renal plasma flow, blood pressure and pulse rate in the equine neonate during the first 10 days post partum.
Equine veterinary journal    August 15, 1998   Volume 30, Issue 4 335-343 doi: 10.1111/j.2042-3306.1998.tb04107.x
Holdstock NB, Ousey JC, Rossdale PD.The aim of this study was to determine glomerular filtration rate (GFR), effective renal plasma flow (RPF) and filtration fraction (FF) values in Pony foals during the first 10 days post partum in order to assess any age-related changes and the reliability of the single injection inulin/p-aminohippurate (PAH) method. Arterial blood pressure and pulse rate were determined in Pony and Thoroughbred (TB) foals during the first 10 days post partum to establish age-related changes, differences between breeds and possible interrelationships with GFR and RPF. Inulin and PAH were injected intravenously...
Cardiovascular effects of surgical castration during anaesthesia maintained with halothane or infusion of detomidine, ketamine and guaifenesin in ponies.
Equine veterinary journal    August 15, 1998   Volume 30, Issue 4 304-309 doi: 10.1111/j.2042-3306.1998.tb04102.x
Taylor PM, Kirby JJ, Shrimpton DJ, Johnson CB.Sixteen colts were premedicated with acepromazine and anaesthesia was induced with detomidine and ketamine. Ponies were randomly allocated to receive halothane (HAL) or infusion of detomidine, ketamine and guaiphenesin (DKG) to maintain anaesthesia. Heart and respiratory rate, ECG, mean arterial blood pressure (MABP), cardiac index (CI), blood gases and plasma cortisol, ketamine and guaiphenesin were measured. Surgical castration took place between 45 and 75 min and anaesthesia lasted 90 min. MABP with DKG was significantly higher than with HAL, and, with HAL, MABP increased from pre-surgery (...
Quantification of exercise-induced pulmonary haemorrhage with bronchoalveolar lavage.
Equine veterinary journal    August 15, 1998   Volume 30, Issue 4 284-288 doi: 10.1111/j.2042-3306.1998.tb04098.x
Meyer TS, Fedde MR, Gaughan EM, Langsetmo I, Erickson HH.Exercise-induced pulmonary haemorrhage (EIPH) causes serious economic losses in the horse racing industry. Endoscopic examination indicates that 40-90% of horses exhibit EIPH following sprint exercise, but the limitations of the endoscope prevent diagnosis in many horses. Bronchoalveolar lavage (BAL) was utilised to detect red blood cells (RBCs) in the terminal airways in 6 horses. Two lavages were performed at weekly intervals prior to exercise, one within 90 min after exercise, and 5 at weekly intervals after exercise. The horses were exercised strenuously at 12.5-14.6 m/s on a treadmill (3 ...
Effect of cisapride on gastric emptying in horses following endotoxin treatment.
Equine veterinary journal    August 15, 1998   Volume 30, Issue 4 344-348 doi: 10.1111/j.2042-3306.1998.tb04108.x
Valk N, Doherty TJ, Blackford JT, Abraha TW, Frazier DL.The effect of cisapride pretreatment on gastric emptying in horses was determined by measuring serum concentrations of acetaminophen, a drug known to be readily absorbed in the small intestine but not in the stomach. The time to reach maximum serum acetaminophen concentrations (Tmax), the maximum serum concentrations (Cmax) and the area under the serum acetaminophen concentration vs. time curves (AUC) were compared among treatment groups. In the first part of the study, the effect of orally administered cisapride (0.1, 0.2 and 0.4 mg/kg bwt) on gastric emptying was examined in 6 normal fasted ...
Lactalbumin-positive mammary carcinoma in a mare.
Equine veterinary journal    August 15, 1998   Volume 30, Issue 4 358-360 doi: 10.1111/j.2042-3306.1998.tb04113.x
Kato M, Higuchi T, Hata H, Ishikawa Y, Kadota K.No abstract available
Low-field magnetic resonance imaging (0.2 T) of tendons with sonographic and histologic correlation. Cadaveric study.
Investigative radiology    August 15, 1998   Volume 33, Issue 8 433-438 doi: 10.1097/00004424-199808000-00002
Rand T, Bindeus T, Alton K, Voegele T, Kukla C, Stanek C, Imhof H.The authors evaluate the role of low-field strength magnetic resonance imaging (MRI) compared with sonography in the evaluation of degenerative changes of tendons, with histologic correlation, based on investigations of horse cadavers. Methods: Low-field MRI and sonography was performed in 42 hours specimens for the evaluation of tendons and ligaments. Magnetic resonance imaging included sagittal and axial T1-weighted, T2-weighted, and gradient echo images. Sonography and MR images were evaluated for degenerative changes or tears and the findings were correlated with the histologic results. Re...
Arterial blood gases and acid-base balance in healthy young and aged horses.
Equine veterinary journal    August 15, 1998   Volume 30, Issue 4 352-354 doi: 10.1111/j.2042-3306.1998.tb04111.x
Aguilera-Tejero E, Estepa JC, López I, Mayer-Valor R, Rodríguez M.No abstract available
A questionnaire survey on nematode control practices on horse farms in Denmark and the existence of risk factors for the development of anthelmintic resistance.
Veterinary parasitology    August 15, 1998   Volume 78, Issue 1 49-63 doi: 10.1016/s0304-4017(98)00117-4
Lendal S, Larsen MM, Bjørn H, Craven J, Chriél M, Olsen SN.A questionnaire survey to obtain information on endoparasite control practices and management on 68 Danish horse farms was undertaken in 1995. The study revealed that foals, young horses and adults were on average, annually treated 4.3, 4.0 and 3.7 times, respectively. The most commonly used drug from 1993-1995 was ivermectin. On average 2.4 different drugs were used annually. The most used method of weight estimation was eye measure: for foals by 78%, for youngsters by 81% and adults by 82% of the herd owners. The most commonly used weight in the dosing of anthelmintics was individual weights...
Survey of anthelmintic resistance on Danish horse farms, using 5 different methods of calculating faecal egg count reduction.
Equine veterinary journal    August 15, 1998   Volume 30, Issue 4 289-293 doi: 10.1111/j.2042-3306.1998.tb04099.x
Craven J, Bjørn H, Henriksen SA, Nansen P, Larsen M, Lendal S.This study reports on the prevalence of anthelmintic resistance in strongyles of horses in Denmark. Of 5 methods used for the calculation of faecal egg count reduction (FECR) the method recommended by the World Association for the Advancement of Veterinary Parasitology, for the detection of resistance in sheep was the most sensitive procedure for detecting resistance. Using this method benzimidazole resistance was detected on 33 of 42 farms (79%) examined. Pyrantel was tested on 15 farms and FECR tests indicate resistance on 3 (30%) farms. On 2 farms on which resistance to pyrantel was detecte...
Water and electrolyte intake and output in conditioned Thoroughbred horses transported by road.
Equine veterinary journal    August 15, 1998   Volume 30, Issue 4 316-323 doi: 10.1111/j.2042-3306.1998.tb04104.x
van den Berg JS, Guthrie AJ, Meintjes RA, Nurton JP, Adamson DA, Travers CW, Lund RJ, Mostert HJ.The objectives of this trial were to measure the water and electrolyte intake and loss, of horses during road transportation in relatively hot environmental conditions. Six mature, Thoroughbred horses in full training were used in a balanced crossover design. The horses were conditioned on a treadmill for 6 weeks before the start of the trial in order to simulate the type of horse that is transported most often over long distances in South Africa. The horses were assigned randomly to one of 2 treatment groups. On a particular day 3 horses were transported, while the other horses served as cont...
Is anthelmintic resistance inevitable: back to basics?
Equine veterinary journal    August 15, 1998   Volume 30, Issue 4 280-283 doi: 10.1111/j.2042-3306.1998.tb04097.x
Lloyd S, Soulsby .No abstract available
Serum gentamicin concentrations in compromised neonatal foals.
Equine veterinary journal    August 15, 1998   Volume 30, Issue 4 324-328 doi: 10.1111/j.2042-3306.1998.tb04105.x
Raisis AL, Hodgson JL, Hodgson DR.Twenty-one compromised neonatal foals hospitalised at the Rural Veterinary Centre (RVC) during 1993 were studied to determine i) serum gentamicin concentrations obtained when gentamicin was administered at 3.3 mg/kg bwt twice daily i.m.; ii) factors which contributed to inter-foal variation in serum gentamicin concentrations achieved and iii) clinical efficacy of gentamicin therapy in foals with confirmed septicaemia. Septicaemia was confirmed in 7 foals with positive blood cultures and suspected in 8 foals with a sepsis score > 11. Peak serum concentrations (Ps) were > 6 microg/ml in al...
Cutaneous lymphoma with extensive periarticular involvement in a horse.
Journal of the American Veterinary Medical Association    August 14, 1998   Volume 213, Issue 3 391-393 
Gerard MP, Healy LN, Bowman KF, Miller RT.Two months after colic surgery, subcutaneous masses were found on the ventral and lateral portions of the thorax of a 3-year-old Hanoverian-cross filly. Six months later, the filly was admitted for evaluation of severe lameness. Arthrocentesis of the tarsocrural joint yielded clotted sanguineous material; however, unusual multinucleated giant cells were seen. Radiography of the right tarsus revealed soft tissue opacity and degenerative joint disease. The filly was euthanatized to prevent further suffering. At necropsy, multiple soft-tissue masses were located throughout the fascial planes of t...
Monitoring and detection of acute viral respiratory tract disease in horses.
Journal of the American Veterinary Medical Association    August 14, 1998   Volume 213, Issue 3 385-390 
Mumford EL, Traub-Dargatz JL, Salman MD, Collins JK, Getzy DM, Carman J.To develop a system to monitor and detect acute infections of the upper respiratory tract (i.e., nares, nasopharynx, and pharynx) in horses and to assess the association among specific viral infections, risk factors, and clinical signs of disease. Methods: Prospective study. Methods: 151 horses with clinical signs of acute infectious upper respiratory tract disease (IURD) from 56 premises in Colorado. Methods: Health management data, blood samples, and nasal or nasopharyngeal swab samples were obtained for 151 horses with clinical signs of acute IURD. Of these horses, 112 had an additional blo...
[Experiences with spermatic cord ligation as a method of castration in the stallion. The surgical castration of the testicle in situ appears to be of value].
Tijdschrift voor diergeneeskunde    August 13, 1998   Volume 123, Issue 14-15 432-434 
Wiemer P.In 22 stallions the surgically prepared spermatic cord was crushed and ligated. Preoperative and postoperative plasma-testosterone concentrations were measured and 60 days after surgery a HCG-stimulation test was carried out in 12 horses. In these 12 horses the testosterone production had ceased. In all 22 horses the wounds healed by primary intention. Ligation of the spermatic cord is a castration technique without surgical complications, at least in this study.
Pegasus joins the jet age.
Australian veterinary journal    August 13, 1998   Volume 76, Issue 7 476-477 doi: 10.1111/j.1751-0813.1998.tb10186.x
Ellis PM.No abstract available
Diversity of genomic electropherotypes of naturally occurring equine herpesvirus 1 isolates in Argentina.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas    August 12, 1998   Volume 31, Issue 6 771-774 doi: 10.1590/s0100-879x1998000600007
Galosi CM, Norimine J, Echeverría MG, Oliva GA, Nosetto EO, Etcheverrigaray ME, Tohya Y, Mikami T.The genomes of 10 equine herpesvirus 1 (EHV-1) strains isolated in Argentina from 1979 to 1991, and a Japanese HH1 reference strain were compared by restriction endonuclease analysis. Two restriction enzymes, BamHI and BglII, were used and analysis of the electropherotypes did not show significant differences among isolates obtained from horses with different clinical signs. This suggests that the EHV-1 isolates studied, which circulated in Argentina for more than 10 years, belong to a single genotype.
Borna disease in Austrian horses.
The Veterinary record    August 12, 1998   Volume 143, Issue 1 21-22 doi: 10.1136/vr.143.1.21
Weissenböck H, Suchy A, Caplazi P, Herzog S, Nowotny N.No abstract available
Use of metronidazole in horses.
The Veterinary record    August 12, 1998   Volume 143, Issue 1 27 
Rutter JM.No abstract available
The potential of collagenase as a new therapy for separation of human retained placenta: hydrolytic potency on human, equine and bovine placentae.
Placenta    August 12, 1998   Volume 19, Issue 5-6 379-383 doi: 10.1016/s0143-4004(98)90077-7
Fecteau KA, Haffner JC, Eiler H.The purpose of this study was to determine to what degree bacterial collagenase may digest human placentae compared to equine and bovine placentae. Placenta samples from human, equine and bovine were incubated with bacterial collagenase solution at various concentrations. The degree of hydrolysis and collagen breakdown was measured by the release of total proteins and hydroxyproline into the incubation media. Also, whole placentae were injected via umbilical cord arteries with collagenase solution (200 U/ml, 200 ml total volume in human and 1000 ml in equine) and hydrolysis determined chemical...
Characterization of 24 equine microsatellite loci.
Animal genetics    August 12, 1998   Volume 29, Issue 2 153-156 
van Haeringen WA, van de Goor LH, van der Hout N, Lenstra JA.No abstract available
Nitrergic relaxation of the horse corpus cavernosum. Role of cGMP.
European journal of pharmacology    August 11, 1998   Volume 351, Issue 1 85-94 doi: 10.1016/s0014-2999(98)00282-9
Recio P, López PG, Hernández M, Prieto D, Contreras J, García-Sacristán A.The involvement of nitric oxide (NO) and the mechanisms mediating neurogenic relaxation were investigated in the horse corpus cavernosum. NADPH-diaphorase activity was expressed in nerve fibres around arteries and muscular bundles in the horse trabecular tissue. Relaxations in response to electrical field stimulation were tetrodotoxin (10(-6) M)-sensitive, indicating their neurogenic origin. The NO synthase inhibitor, L-NO-arginine (L-NO-Arg, 3 x 10(-5) M), abolished the electrically induced relaxations, which were significantly reversed by L-arginine (3 x 10(-3) M). Exogenous NO (10(-6)-10(-3...
A comparative study of mast cells and eosinophil leukocytes in the mammalian testis.
Zentralblatt fur Veterinarmedizin. Reihe A    August 11, 1998   Volume 45, Issue 4 209-218 doi: 10.1111/j.1439-0442.1998.tb00819.x
Anton F, Morales C, Aguilar R, Bellido C, Aguilar E, Gaytán F.The existence of a physiological integration between the immune and endocrine systems has long been recognized. In spite of the abundant literature data on the presence of cells of the immune system in the testis, mast cells and eosinophil leukocytes have received little attention. We have studied the presence, distribution and numbers of mast cells and eosinophils in the testes of 12 mammalian species. Mast cells were frequently found in equine (stallion, ass and mule) and human testis, whereas eosinophils were nearly absent. On the contrary, eosinophils were abundant in the hare testis, whil...
Screening of chlorpropamide in horse plasma by high-performance liquid chromatography with ultraviolet absorbance detection, and confirmation by gas chromatography-mass spectrometry.
Journal of chromatography. B, Biomedical sciences and applications    August 11, 1998   Volume 712, Issue 1-2 243-252 doi: 10.1016/s0378-4347(98)00184-4
Chua HC, Stewart B, Lim BH, Lee HK.A chromatographic method was developed to detect and confirm the presence of chlorpropamide (I) in horse plasma samples, for antidoping control. The plasma sample (1 ml) was extracted with dichloromethane and screened by high-performance liquid chromatography, and confirmation of the drug's presence was accomplished by using gas chromatography-mass spectrometry (GC-MS). The limit of detection was found to be 3.5 ng/ml at a signal-to-noise ratio of three. Derivatization of I with N,O-bis-(trimethylsilyl)trifluoroacetamide with 1% trimethylchlorosilane allowed for highly stable, accurate and sen...
Effect of sodium methyl arsinate and imidocarb dipropionate antiprotozoal drugs on the pharmacokinetic of gentamicin in equines.
DTW. Deutsche tierarztliche Wochenschrift    August 11, 1998   Volume 105, Issue 7 274-276 
Soliman GA.The pharmacokinetic behaviour of gentamicin sulphate (3.4 mg/kg bwt) was studied following its intramuscular injection to a group of horses and to another group of horses premedicated with sodium methyl arsinate (2 mg/kg bwt) or imidocarb dipropionate (4.8 mg/kg bwt). Considerable differences were observed in the pharmacokinetics of gentamicin in pre-medicated horses and in horses which had received the antibiotic alone. Peak serum concentration of gentamicin (9.85 +/- 0.05 and 11.15 +/- 0.15 micrograms/ml) were attained within 1.45 +/- 0.05 and 0.92 +/- 0.04 h in arsinate and imidocarb-medica...
Pharmacokinetics of sulfonamides and trimethoprim in the donkey (Equus asinus).
Zentralblatt fur Veterinarmedizin. Reihe A    August 11, 1998   Volume 45, Issue 4 191-198 doi: 10.1111/j.1439-0442.1998.tb00817.x
Oukessou M, Alsouss L.The body disposition of sulfadimidine (SDM), sulfadiazine (SDZ), sulfamethoxypyridazine (SMPZ) and a trimethoprim-sulfadimethoxine combination (TMP-SDMX) was investigated in the donkey. The four sulfonamides and TMP were injected intravenously at doses of 20 mg/kg (SDM, SDZ, SMPZ), 12.5 mg/kg (SDMX) and 2.5 mg/kg (TMP). The body clearance (ClB) of SDZ (1.70 +/- 0.14 ml/min/kg) was significantly higher than those of SDM (1.13 +/- 0.18 ml/min/kg), SMPZ (1.10 +/- 0.09 ml/min/kg) and SDMX (0.75 +/- 0.04 ml/min/kg). In contrast, the volume of distribution at steady state (Vss) was similar for the f...
Comparative molecular characterization of Corynebacterium pseudotuberculosis of different origin.
Veterinary microbiology    August 8, 1998   Volume 62, Issue 2 135-143 doi: 10.1016/s0378-1135(98)00202-8
Costa LR, Spier SJ, Hirsh DC.Ribotyping and susceptibility to 17 antimicrobial agents were used to compare 37 isolates of Corynebacterium pseudotuberculosis (28 from horses, 1 from cattle, 3 from sheep and 5 from goats) derived from various types of lesions, and different geographic locations. According to the presence of nitrate reductase, all but one isolate from horses reduced nitrate (nitrate-positive), whereas all isolates from sheep and goats were unable to reduce nitrate (nitrate-negative). The ribotype of the nitrate-negative isolate from a horse with ulcerative lymphangitis was identical to all the other isolates...
Equine infectious anemia virus is found in tissue macrophages during subclinical infection.
Journal of virology    August 8, 1998   Volume 72, Issue 9 7263-7269 doi: 10.1128/JVI.72.9.7263-7269.1998
Oaks JL, McGuire TC, Ulibarri C, Crawford TB.The equine infectious anemia virus (EIAV) often results in lifelong subclinical infection following early episodes of clinical disease. To identify the cellular reservoirs of EIAV during subclinical infection, horses were infected with EIAV and allowed to develop subclinical infections. Horses with acute disease served as a basis for comparison. The tissue distribution, replication status, location of infected cells, and viral load were characterized by PCR for proviral DNA and reverse transcriptase PCR for viral RNA, in situ hybridization, and in situ PCR. Proviral DNA was widespread in tissu...
A waveguide-based acoustic microscope.
Ultrasonics    August 8, 1998   Volume 36, Issue 8 855-863 doi: 10.1016/s0041-624x(98)00014-6
Peterson ML, Srinath S, Murphy J.A new instrument is presented which is capable of high resolution acoustic imaging at relatively low frequencies. This approach results in increased complexity of the signal processing required and reduced throughput of the instrument. However, these disadvantages are amply compensated by the ability to create velocity scan images of materials with either high attenuation or low material velocities. These measurements are not possible using traditional/acoustic microscopes. The initial performance of the new instrument is demonstrated using thin samples of shim materials to show that acceptabl...
The horse as a model for thermoregulatory responses to exercise.
International journal of sports medicine    August 7, 1998   Volume 19 Suppl 2 S100-S102 doi: 10.1055/s-2007-971968
McConaghy FF, Hodgson DR, Hales JR, Rose RJ.No abstract available