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Topic:Veterinary Medicine

Veterinary medicine for horses encompasses the study and application of medical practices to diagnose, treat, and prevent diseases in equine species. This field involves a comprehensive understanding of equine anatomy, physiology, pathology, and pharmacology. Veterinary practitioners employ a range of diagnostic tools and therapeutic interventions to address health issues in horses, including lameness, gastrointestinal disorders, respiratory conditions, and infectious diseases. Preventative care, such as vaccination and deworming programs, is also a significant aspect of equine veterinary medicine. This page gathers peer-reviewed research studies and scholarly articles that explore various aspects of veterinary medicine as it pertains to horses, including advancements in diagnostic techniques, treatment protocols, and preventive health strategies.
Distribution of filipin-sterol complexes in the plasma membrane of stallion spermatozoa during the epididymal maturation process.
Molecular reproduction and development    February 1, 1991   Volume 28, Issue 2 158-168 doi: 10.1002/mrd.1080280209
López ML, de Souza W.The presence and distribution of cholesterol in mature and immature epididymal spermatozoa was analyzed using filipin as a cytochemical tool in freeze-fracture replicas and thin section preparations. The polyenic-antibiotic filipin formed complexes with 3, beta -OH sterols, producing characteristic protrusions, or pits, that were heterogeneously distributed in the plasma membrane of stallion spermatozoa, revealing a specific organization in a functionally specialized area of the gamete. The acrosomal region of the sperm head presented a significantly higher density of filipin sterol complexes ...
[The effects of crude drugs using diuretic on horse kidney (Na+ + K+)-adenosine triphosphatase].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan    February 1, 1991   Volume 111, Issue 2 138-145 doi: 10.1248/yakushi1947.111.2_138
Satoh K, Yasuda I, Nagai F, Ushiyama K, Akiyama K, Kano I.In the folk-medicine, several kinds of crude drugs are used as diuretics. Twenty three kinds of diuretic drugs were chosen, and examined for their effects on the horse kidney (Na+ + K+)-adenosine triphosphatase (ATPase), which is an intrinsic enzyme of the plasma membrane and responsible for the active transport of Na+ and K+ across the membrane. Twenty one out of twenty three kinds of ethanol extracts of diuretic drugs inhibited the kidney (Na+ + K+)-ATPase activity. The intensity of the inhibition of these drugs was compared by estimating the amounts of their ethanol extracts which inhibited...
Equine cutaneous mastocytoma: morphology, biological behaviour and evolution of the lesion.
Journal of comparative pathology    February 1, 1991   Volume 104, Issue 2 171-178 doi: 10.1016/s0021-9975(08)80100-4
McEntee MF.Thirty equine cutaneous mastocytomas were examined histologically and two were studied ultrastructurally. Lesions were characterized by distinct sheets of well-differentiated mast cells with variable degrees of eosinophil infiltration, collagen degeneration, necrosis, granulomatous inflammation and fibrosis. Twenty-two of 25 growths did not recur for up to 6 years after surgical excision, two recurred at the surgical site and one spontaneously regressed less than 3 months after obtaining a biopsy sample. Equine cutaneous mastocytoma is a benign proliferative lesion which seldom recurs after ex...
Avocado (Persea americana) poisoning of horses.
Australian veterinary journal    February 1, 1991   Volume 68, Issue 2 77-78 doi: 10.1111/j.1751-0813.1991.tb03147.x
McKenzie RA, Brown OP.No abstract available
[A case of diprosopus in a foal].
Tierarztliche Praxis    February 1, 1991   Volume 19, Issue 1 82-83 
Götz HJ.A case of diprosopus in a foal is described. This is only the second report of such a deformity in the equine species. Hereditary pathology and pathogenesis are discussed.
Effect of increased inspired CO2 on respiratory dead space in ponies.
Journal of applied physiology (Bethesda, Md. : 1985)    February 1, 1991   Volume 70, Issue 2 732-739 doi: 10.1152/jappl.1991.70.2.732
Lowry TF, Forster HV, Forster MA, Murphy CL, Brice AG, Pan LG.The objective of the present study was to determine the effect of elevated inspired CO2 on respiratory dead space (VD) of 12 normal, 8 carotid body-denervated (CBD), 7 hilar nerve-denervated (HND), and 6 CBD+HND ponies. The Fowler technique was used to determine VD on a breath-by-breath basis while the ponies breathed room air and inspired CO2 at 3 and 6%. During room air breathing, tidal volume (VT) and VD were greater in HND ponies than in normal and CBD ponies (P less than 0.05), and VT was less and VD/VT was greater after CBD than before CBD. For all groups. VD, VT, and breathing frequency...
Biochemical study of repair of induced osteochondral defects of the distal portion of the radial carpal bone in horses by use of periosteal autografts.
American journal of veterinary research    February 1, 1991   Volume 52, Issue 2 328-332 
Vachon AM, McIlwraith CW, Keeley FW.Periosteal autografts were used for repair of large osteochondral defects in 10 horses aged 2 to 3 years old. In each horse, osteochondral defects measuring 1.0 x 1.0 cm2 were induced bilaterally on the distal articular surface of each radial carpal bone. Control and experimental defects were drilled. Periosteum was harvested from the proximal portion of the tibia and was glued into the principal defects, using a fibrin adhesive. Control defects were glued, but were not grafted. Sixteen weeks after the grafting procedure, the quality of the repair tissue of control and grafted defects was asse...
[Symptomatology and diagnosis of Borna encephalitis of horses. A case analysis of the last 13 years].
Tierarztliche Praxis    February 1, 1991   Volume 19, Issue 1 68-73 
Grabner A, Fischer A.In a retrospective study of 38 horses with Borna encephalitis which were clinically and histopathologically examined in the "I. Medizinische Tierklinik" in Munich between 1977 and 1990, the epidemiology, the clinical symptomatic and the diagnostic procedures available are presented. Indirect immunofluorescence showed antibodies in the serum of 12 out of 29 cases (41%) and in the cerebrospinal fluid (CSF) of 17 out of 28 cases (61%). The evaluation of 23 cases in which indirect immunofluorescence of serum and CSF, and also the post mortem virological and histopathological examination of the bra...
Effect of aspiration of the preovulatory follicle on luteinization, corpus luteum function, and peripheral plasma gonadotropin concentrations in the mare.
Biology of reproduction    February 1, 1991   Volume 44, Issue 2 292-298 doi: 10.1095/biolreprod44.2.292
Hinrichs K, Rand WM, Palmer E.Follicular fluid from small- to medium-sized follicles has been shown to have an inhibiting effect on luteinization of granulosa cells in vitro. This study was conducted to investigate the effect of in vivo removal of follicular fluid on luteinization, peripheral gonadotropin concentrations, and ovulation of secondary follicles in the mare. Follicular fluid was aspirated from the preovulatory follicles of mares when the diameter of the follicle was 30-34 mm (Group A), 35-39 mm (Group B), or 40-44 mm (Group C). Mares in Group D served as controls and the preovulatory follicle was not aspirated....
Effects of increased end-expiratory lung volume on breathing in awake ponies.
Journal of applied physiology (Bethesda, Md. : 1985)    February 1, 1991   Volume 70, Issue 2 715-725 doi: 10.1152/jappl.1991.70.2.715
Brice AG, Forster HV, Pan LG, Lowry TF, Murphy CL, Mead J.We studied the changes in breathing and respiratory muscle electromyograms (EMG) during passively induced increases in end-expiratory lung volume (EELV) in awake normal (N), hilar nerve-denervated (HND), carotid body-denervated (CBD), and HND + CBD ponies. EELV was increased by applying continuous negative pressure (-10 and -20 cmH2O) around the torso of the standing pony. In all groups, negative pressure produced sustained increases in EELV that were linearly related to the degree of negative pressure. Elevated EELV decreased breathing frequency (f) in N and CBD ponies but increased f in HND ...
Atrial septal defect and atrial fibrillation in a foal.
The Veterinary record    January 26, 1991   Volume 128, Issue 4 80-81 doi: 10.1136/vr.128.4.80
Taylor FG, Wotton PR, Hillyer MH, Barr FJ, Lucke VM.Clinical examination of a four-and-a-half-month old foal revealed evidence of progressive heart failure associated with an atrial septal defect and atrial fibrillation. Atrial septal defects are rarely reported in foals and the foal's growth, development and demeanour were normal until a sudden onset of lethargic behaviour. The value of B-mode echocardiography in identifying the congenital lesion is indicated.
Determination of isoxsuprine in equine plasma by high-performance liquid chromatography with electrochemical detection.
Journal of chromatography    January 18, 1991   Volume 563, Issue 1 216-223 doi: 10.1016/0378-4347(91)80299-r
Hashem A, Lubczyk B.No abstract available
Prognostic factors and survival of horses with ocular/adnexal squamous cell carcinoma: 147 cases (1978-1988).
Journal of the American Veterinary Medical Association    January 15, 1991   Volume 198, Issue 2 298-303 
Dugan SJ, Roberts SM, Curtis CR, Severin GA.Between January 1978 and December 1988, 147 horses with ocular/adnexal squamous cell carcinoma (SCC) were admitted to the Colorado State University Veterinary Teaching Hospital (CSU-VTH). Diagnosis was confirmed by histologic examination of appropriate tissue specimens. Medical records and communication with owners, referring veterinarians, or both provided information regarding initial examination, treatment at the CSU-VTH, and final outcome. At initial examination, 123 (83.7%) horses had unilateral involvement and 24 (16.3%) horses had bilateral involvement. The nictitating membrane, nasal c...
Epidemiologic study of ocular/adnexal squamous cell carcinoma in horses.
Journal of the American Veterinary Medical Association    January 15, 1991   Volume 198, Issue 2 251-256 
Dugan SJ, Curtis CR, Roberts SM, Severin GA.Proportional hospital accession ratios for equine ocular/adnexal squamous cell carcinoma (SCC) were determined for 14 colleges of veterinary medicine participating in the Veterinary Medical Data Program between January 1978 and December 1986. Comparison of the ratios with their respective geographical, physical data has shown an increased prevalence of SCC with an increase in longitude, altitude, or mean annual solar radiation. In contrast, prevalence of SCC increased with a decrease in latitude. Between January 1978 and December 1988, 147 horses with ocular/adnexal SCC were admitted to the Co...
Use of gastrotomy to relieve esophageal obstruction in a horse.
Journal of the American Veterinary Medical Association    January 15, 1991   Volume 198, Issue 2 295-296 
Orsini JA, Dikes N, Ruggles A, Charlton C, Perry R.Esophageal obstruction of 1 week's duration in a gelding was diagnosed by contrast radiography and esophagoscopy. A food bolus was found at the junction of the caudal thoracic portion of the esophagus and the cardia. A gastrotomy was performed through a cranial abdominal incision and a phytobezoar was manually broken down and removed. The gelding was started on complete pellet food and water on the fifth day after surgery. The horse remained clinically normal more than 1 year after surgery.
[A horse seropositive for Ehrlichia risticii].
Tijdschrift voor diergeneeskunde    January 15, 1991   Volume 116, Issue 2 69-72 
van der Kolk JH, Bernadina WE, Visser IJ.A four year old Dutch warmblooded mare was born and raised in the province of North-Brabant, the Netherlands. On May 16, 1989, she showed signs of colic, anorexia, depression, ileus, severe dehydration and leukopenia. When the mare collapsed, euthanasia was carried out. Acute colitis and cytoplasmic inclusion bodies in macrophages were observed at autopsy. When an indirect immunofluorescence assay was performed, the Ehrlichia risticii titre of the serum was found to be 1:640.
Atypical myoglobinuria.
The Veterinary record    January 12, 1991   Volume 128, Issue 2 44 doi: 10.1136/vr.128.2.44-a
Robinson HC.No abstract available
Interpretation of dope test results in racehorses.
The Veterinary record    January 12, 1991   Volume 128, Issue 2 41 doi: 10.1136/vr.128.2.41
Sanford J.No abstract available
Myocardial blood flow, metabolism, and function with repeated brief coronary occlusions in conscious ponies.
The American journal of physiology    January 11, 1991   Volume 260, Issue 1 Pt 2 H100-H109 doi: 10.1152/ajpheart.1991.260.1.H100
Williams DO, Boatwright RB, Rugh KS, Garner HE, Griggs DM.Studies were performed in the conscious pony instrumented with a Doppler flow probe and hydraulic occluder on the left anterior descending coronary artery (LAD), sonomicrometry crystals and intraventricular micromanometer in the left ventricle, and catheters in the left atrium and anterior interventricular vein. Two-minute LAD occlusions were performed every 30 min continuously or during working hours. Data on release of catabolites (potassium, hydrogen ions, and lactate) and norepinephrine from the initially dysfunctional region were obtained periodically during a regimen of 445 +/- 56 occlus...
Atlantoaxial malformation in a half-Arabian colt.
The Cornell veterinarian    January 11, 1991   Volume 81, Issue 1 67-75 
Blikslager AT, Wilson DA, Constantinescu GM, Miller MA, Corwin LA.A 1-year-old half-Arabian colt was referred for evaluation of a cranial cervical abnormality. Physical examination revealed the left wing of the atlas to be more ventral than the right wing. A head tilt, with the pole deviated to the left, was present because of the malpositioned atlas. Neurologic examination identified symmetrical weakness, ataxia, and proprioceptive deficits in all four limbs. Radiographs of the cranial cervical region revealed fusion of the atlas and axis, and deviation of the atlantoaxial joint to the left of the median plane. Euthanasia was elected. Necropsy confirmed the...
Calmodulin-mediated adenylyl cyclase from equine sperm.
Methods in enzymology    January 11, 1991   Volume 195 91-110 doi: 10.1016/0076-6879(91)95157-f
Toscano WA, Gross MK.No abstract available
Immunohistochemical diagnosis of protozoan parasites in lesions of equine protozoal myeloencephalitis. Granstrom DE, Giles RC, Tuttle PA, Williams NM, Poonacha KB, Petrites-Murphy MB, Tramontin RR, Swerczek TW, Hong CB, Rezabek GB.No abstract available
Clinical signs, laboratory changes and toxicokinetics of brodifacoum in the horse. Boermans HJ, Johnstone I, Black WD, Murphy M.Six horses gavaged with a commercial brodifacoum (BDF)-containing bait (Talone) at a dosage of 0.125 mg of BDF/kg of body weight showed weight loss, severe hypocoagulability and hemogram alterations. Four of the horses became depressed and anorectic; one required vitamin K1 therapy. Increases in clotting times were observed at 24 h in the partial thromboplastin time (PTT) followed by the thrombotest (TBT) and one-stage prothrombin time (PT) at 48 h. Elevated mean PTT, PT and TBT were observed from days 4 to 8 (p less than 0.05) with levels returning to pretreatment levels by day 12. Maximum pr...
Purification of equine neutrophil lysozyme and its antibacterial activity against gram-positive and gram-negative bacteria.
Veterinary research communications    January 1, 1991   Volume 15, Issue 6 427-435 doi: 10.1007/BF00346538
Pellegrini A, Waiblinger S, Von Fellenberg R.Lysozyme from equine neutrophil granulocytes was isolated in a pure form by fast performance liquid chromatography, i.e. ion-exchange chromatography and reversed-phase chromatography. The lysozyme lysed Micrococcus luteus, Bacillus subtilis and Staphylococcus lentus and was also bactericidal against the Gram-negative bacteria Escherichia coli, Klebsiella pneumoniae, Bordetella bronchiseptica, and Serratia marcescens. Staphylococcus aureus and Staphylococcus epidermidis were not lysed. The lysozyme was only very slightly bactericidal for S. epidermidis and S. aureus. Equine neutrophil lysozyme ...
Experimental models of endotoxaemia related to abortion in the mare.
Journal of reproduction and fertility. Supplement    January 1, 1991   Volume 44 509-516 
Kindahl H, Daels P, Odensvik K, Daunt D, Fredricksson G, Stabenfeldt G, Hughes JP.Three different routes of administering Salmonella typhimurium endotoxin to mimic naturally occurring endotoxaemia were tried in the mare. Bolus injection, repeated bolus injections and continuous low-dose infusion were compared with prostaglandin F2 alpha release, leucocyte count and clinical response. A biphasic prostaglandin release and a pronounced leucopenia of almost identical patterns were seen in all models. Repeated bolus injections showed that the second injection initiated only a small prostaglandin release indicating the development of refractoriness to the treatment. A similar ref...
Rethinking endotoxaemia in 1991.
Equine veterinary journal    January 1, 1991   Volume 23, Issue 1 3-4 doi: 10.1111/j.2042-3306.1991.tb02701.x
Moore JN.No abstract available
Inheritance of the equine Tf F3 allele.
Animal genetics    January 1, 1991   Volume 22, Issue 2 187-190 doi: 10.1111/j.1365-2052.1991.tb00662.x
Cothran EG, Henney PJ, King JA.The inheritance of the equine Tf F3 allele was examined in 39 parent-offspring combinations. For 26 of the cases the allele inherited by the offspring from the heterozygous parent could be determined. The proportion of individuals that inherited the F3 variant compared to the alternative allele was exactly 1:1. In five cases the parental phenotype was identical to that of the offspring. For the remaining eight cases the parent was homozygous for the F3 allele and all offspring had the F3 allele. The results were consistent with Mendelian inheritance.
A rare GC mutant in horses disclosed by isoelectric focusing and subsequent immunoprinting.
Experimental and clinical immunogenetics    January 1, 1991   Volume 8, Issue 1 49-54 
Cleve H, Schmid DO.An apparent incompatibility in the GC/DBP system in a mare and her colt was found after classification by polyacrylamide gel electrophoresis. Because of this observation an analysis of the equine GC/DBP system by isoelectric focusing and subsequent immunoprinting was initiated. Further GC subtypes, however, were not encountered: the three phenotypes GC F, FS and S were also delineated by this method. The GC types in the case of disputed descent were dissolved: GC S was found in the mare and GC FS in her colt as well as in another of her male offspring. It is proposed that a rare GC mutant is r...
The morphology of abdominal and inguinal cryptorchid testes in stallions: a light and electron microscopic study.
International journal of fertility    January 1, 1991   Volume 36, Issue 1 57-64 
al-Bagdadi F, Hoyt P, Karns P, Martin G, Memon M, McClure R, McCoy D, Shoemaker S.Eleven unilateral cryptorchid stallions, two to three years old, were castrated at Louisiana State University Veterinary Teaching Hospital. Five of these cryptorchid cases were abdominal and the rest were inguinal. This study was initiated to document the differences between the abdominal and inguinal equine cryptorchid testes. Specimens were obtained from the abepididymal side of each cryptorchid testes and processed for light and electron microscopic study. The cryptorchid testes were smaller than the scrotal testes, with the abdominal testes being one-fourth the size of the scrotal testes. ...
Establishment of equine oviduct cell monolayers for co-culture with early equine embryos.
Journal of reproduction and fertility. Supplement    January 1, 1991   Volume 44 393-403 
Battut I, Bézard J, Palmer E.A culture for equine oviduct epithelial cells is described. Primary cultures reached confluence in 5-8 days, forming a monolayer of polygonal cells and remaining morphologically intact for about 20 days. Subcultures were obtained by collecting cells detached spontaneously from the monolayers, and confluence was reached again after 5-7 days. Cells frozen before primary culture were confluent 10-15 days after thawing. Dishes containing confluent cells also were frozen, and some cohesive monolayers formed after thawing. Equine embryos, collected 2 days after ovulation, were cultured alone or with...