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Topic:Veterinary Medicine

Veterinary medicine for horses encompasses the study and application of medical practices to diagnose, treat, and prevent diseases in equine species. This field involves a comprehensive understanding of equine anatomy, physiology, pathology, and pharmacology. Veterinary practitioners employ a range of diagnostic tools and therapeutic interventions to address health issues in horses, including lameness, gastrointestinal disorders, respiratory conditions, and infectious diseases. Preventative care, such as vaccination and deworming programs, is also a significant aspect of equine veterinary medicine. This page gathers peer-reviewed research studies and scholarly articles that explore various aspects of veterinary medicine as it pertains to horses, including advancements in diagnostic techniques, treatment protocols, and preventive health strategies.
Outcome of desmoplasty and fasciotomy for desmitis involving the origin of the suspensory ligament in horses: 27 cases (1995-2004).
Journal of the American Veterinary Medical Association    August 3, 2006   Volume 229, Issue 3 407-412 doi: 10.2460/javma.229.3.407
Hewes CA, White NA.To determine outcome of percutaneous ultrasound-guided desmoplasty with simultaneous fasciotomy for proximal suspensory desmitis (ie, desmitis of the origin of the suspensory ligament) in horses that have not responded to stall rest. Methods: Retrospective case series. Methods: 27 horses. Methods: Medical records of horses with proximal suspensory desmitis treated by means of desmoplasty with fasciotomy were reviewed. Follow-up information was obtained through telephone conversations with owners and trainers of the horses or by examination of horses at the hospital. Results: 23 of the 27 (85%)...
Vascular distribution of contrast medium during intraosseous regional perfusion of the distal portion of the equine forelimb.
American journal of veterinary research    August 3, 2006   Volume 67, Issue 8 1445-1452 doi: 10.2460/ajvr.67.8.1445
Keys GJ, Berry DB, Pleasant RS, Jones JC, Freeman LE.To describe the vascular distribution pattern of contrast medium during intraosseous regional perfusion (IORP) of the distal portion of the equine forelimb. Methods: 13 cadaveric forelimbs from 12 horses without forelimb diseases. Methods: Serial lateromedial radiographic views were taken of the distal portion of 10 heparinized cadaveric forelimbs at 0, 1, 2, 6, 15, and 30 minutes during IORP of the third metacarpal bone (MCIII) by use of iodinated contrast medium and a tourniquet placed over the proximal portion of MCIII. Vascular regions of interest (ROI) were created for each radiograph. Re...
Classification of Actinobacillus spp isolates from horses involved in mare reproductive loss syndrome.
American journal of veterinary research    August 3, 2006   Volume 67, Issue 8 1426-1432 doi: 10.2460/ajvr.67.8.1426
Donahue JM, Sells SF, Bolin DC.To identify Actinobacillus spp isolates recovered from fetuses and pericardial fluid from horses affected with mare reproductive loss syndrome (MRLS) and determine whether these bacterial species are the same as those isolated from clinically normal horses. Methods: Isolates of actinobacilli recovered from 18 horses with pericarditis and 109 fetuses aborted by mares affected by MRLS. Procedures-Actinobacillus spp isolates were identified to the level of species or subspecies by use of conventional phenotypic tests and biochemical and enzyme test kits. The 16S rRNA gene from selected isolates w...
Septic arthritis, tenosynovitis, and infections of hoof structures.
The Veterinary clinics of North America. Equine practice    August 3, 2006   Volume 22, Issue 2 363-viii doi: 10.1016/j.cveq.2006.03.005
Lugo J, Gaughan EM.Infectious diseases of synovial and hoof structures in horses can be devastating to soundness and can result in life-threatening complications. Timely diagnosis and early aggressive treatment can result in successful outcomes and resumption of athletic careers; however, delays in recognition and therapy can be the most costly reasons for failure. Sterilization of affected compartments and tissues requires removal of microorganisms and compromised tissue. Debridement, lavage, and appropriate antimicrobial drug use are the most reliable avenues of treatment. Antimicrobial drugs can be administer...
Infections in the equine abdomen and pelvis: perirectal abscesses, umbilical infections, and peritonitis.
The Veterinary clinics of North America. Equine practice    August 3, 2006   Volume 22, Issue 2 419-ix doi: 10.1016/j.cveq.2006.04.002
Elce YA.This article addresses the pathophysiology, diagnosis, management, and prognosis of several different infections within the equine abdomen and pelvic region. The latest advances in the diagnosis and treatment of perirectal abscesses, umbilical infections, and local and diffuse peritonitis are discussed. Emphasis is placed on recent advances in diagnostics and therapeutics with reference to human literature that may be useful in equine practice.
Meningitis and encephalomyelitis in horses.
The Veterinary clinics of North America. Equine practice    August 3, 2006   Volume 22, Issue 2 553-x doi: 10.1016/j.cveq.2006.03.003
Pellegrini-Masini A, Livesey LC.This article provides an overview of meningitis and encephalomyelitis in horses, including diagnostic tests, treatment developments, and preventative measures reported in the equine and human medical literature of the past few years.
Pathophysiology, diagnosis, and management of urinary tract infection in horses.
The Veterinary clinics of North America. Equine practice    August 3, 2006   Volume 22, Issue 2 497-x doi: 10.1016/j.cveq.2006.03.004
Frye MA.Equine urinary tract infection (UTI) most commonly occurs as a sequela to structural or functional inhibition of normal urine flow. Although it is an infrequent diagnosis in equids, the incidence of UTI in human beings is high and has inspired great investigative effort. The resultant findings with potentially broad application as well as current equine studies are reviewed here. Recent developments in the understanding of host-agent interactions and renal defense mechanisms, emerging antimicrobial resistance, and novel therapeutic alternatives to prophylactic antibiotic use are emphasized.
Use of infrared spectroscopy for diagnosis of traumatic arthritis in horses.
American journal of veterinary research    August 3, 2006   Volume 67, Issue 8 1286-1292 doi: 10.2460/ajvr.67.8.1286
Vijarnsorn M, Riley CB, Shaw RA, McIlwraith CW, Ryan DA, Rose PL, Spangler E.To evaluate use of infrared spectroscopy for diagnosis of traumatic arthritis in horses. Methods: 48 horses with traumatic arthritis and 5 clinically and radiographically normal horses. Methods: Synovial fluid samples were collected from 77 joints in 48 horses with traumatic arthritis. Paired samples (affected and control joints) from 29 horses and independent samples from an affected (n = 12) or control (7) joint from 19 horses were collected for model calibration. A second set of 20 normal validation samples was collected from 5 clinically and radiographically normal horses. Fourier transfor...
Surgical and traumatic wound infections, cellulitis, and myositis in horses.
The Veterinary clinics of North America. Equine practice    August 3, 2006   Volume 22, Issue 2 335-viii doi: 10.1016/j.cveq.2006.04.003
Adam EN, Southwood LL.Surgical site infections (SSIs) and traumatic wound management remain challenging clinical scenarios. The prevention of SSIs involves meticulous surgical technique and aftercare. Traumatic wounds require thorough evaluation to assess the involvement of synovial structures and radiographs to check for fractures. Chronic wounds can require a biopsy and histologic evaluation to obtain a diagnosis, because many underlying pathologic processes grossly appear similar but different treatment regimens are required. Early recognition and diagnosis of cellulitis and myositis enable the rapid aggressive ...
Septicemia and cardiovascular infections in horses.
The Veterinary clinics of North America. Equine practice    August 3, 2006   Volume 22, Issue 2 481-ix doi: 10.1016/j.cveq.2006.03.007
Jesty SA, Reef VB.This article first reviews cardiovascular infections, including endocarditis, myocarditis, vasculitis, and pericarditis. It then addresses what is known at this stage about the effects of sepsis on the cardiovascular system. Some information is provided from current human literature to familiarize the reader with the diagnostics and therapeutics that may eventually be used in equine practice as well.
Enteritis and colitis in horses.
The Veterinary clinics of North America. Equine practice    August 3, 2006   Volume 22, Issue 2 437-ix doi: 10.1016/j.cveq.2006.03.008
Feary DJ, Hassel DM.Enteritis and colitis remain challenging and life-threatening diseases despite many recent advances. Successful treatment is largely dependent on early recognition and directed therapy, which is facilitated by obtaining a complete history and physical examination. A number of new therapies and methods of monitoring critically ill patients have become integral components of treatment success. The critical monitoring of equine foals and adults continues to be an exciting and emerging field.
Reproductive tract infections in horses.
The Veterinary clinics of North America. Equine practice    August 3, 2006   Volume 22, Issue 2 519-x doi: 10.1016/j.cveq.2006.03.010
Lu KG, Morresey PR.Diagnosis, treatment, and, ultimately, prevention of reproductive disease are vital components of equine veterinary medicine. A thorough understanding of anatomy and physiology is necessary to reconcile the pathologic findings of disease. Only then can a rational treatment plan be formulated. Many recent advances in knowledge about the reproductive system of multiple species have application to the mare and stallion.
Advanced techniques in the diagnosis and management of infectious pulmonary diseases in horses.
The Veterinary clinics of North America. Equine practice    August 3, 2006   Volume 22, Issue 2 633-xi doi: 10.1016/j.cveq.2006.03.001
Brown VA, Wilkins PA.Techniques for novel approaches to the diagnosis and management of equine pulmonary disease continue to be developed and used in clinical practice. Diagnostic techniques involving immunoassays and nucleic acid-based tests not only decrease the time in which results become available but increase the sensitivity and specificity of test results. These assays do not substitute for careful clinical evaluation but can shorten the time to a confirmed accurate diagnosis, and thus allow for early initiation of therapeutic strategies and prevention protocols. With further understanding of the molecular ...
Osteomyelitis in horses.
The Veterinary clinics of North America. Equine practice    August 3, 2006   Volume 22, Issue 2 389-ix doi: 10.1016/j.cveq.2006.04.001
Goodrich LR.Much has been learned in the past decade about osteomyelitis. The inhibitory mechanisms of the "biofilm slime" layer that is formed by bacterial extracapsular exopolysaccharides and binds to bone, joints, and implants are now better understood than in the past. The surface colonization of bacteria that occurs within these biofilms is a biologic phenomenon that is somewhat unique to orthopedic infections. This survival strategy of bacteria is effective, and it is important for veterinarians who treat osteomyelitis to be aware of current diagnostic and therapeutic treatment modalities. The pract...
Prevention of postoperative infections in horses.
The Veterinary clinics of North America. Equine practice    August 3, 2006   Volume 22, Issue 2 323-viii doi: 10.1016/j.cveq.2006.03.002
Santschi EM.The best defense against postoperative infection is to use multiple strategies to minimize wound contamination, maintain wound tissue health, and provide rational antimicrobial strategies that do not promote the development of resistant bacteria and superinfections.
Exclusion of linkage of the RYR1, CACNA1S, and ATP2A1 genes to recurrent exertional rhabdomyolysis in Thoroughbreds.
American journal of veterinary research    August 3, 2006   Volume 67, Issue 8 1395-1400 doi: 10.2460/ajvr.67.8.1395
Dranchak PK, Valberg SJ, Onan GW, Gallant EM, Binns MM, Swinburne JE, Mickelson JR.To determine whether there was genetic linkage between the recurrent exertional rhabdomyolysis (RER) trait in Thoroughbred horse pedigrees and DNA markers in genes (the sarcoplasmic reticulum calcium release channel [RYR1] gene, the sarcoplasmic reticulum calcium ATPase [ATP2A1] gene, and the transverse tubule dihydropyridine receptor-voltage sensor [CACNA1S] gene) that are important in myoplasmic calcium regulation. Methods: 34 horses in the University of Minnesota RER resource herd and 62 Thoroughbreds from 3 families of Thoroughbreds outside of the university in which RER-affected status wa...
Temporomandibular joint cytokine profiles in the horse.
Journal of veterinary dentistry    August 2, 2006   Volume 23, Issue 2 83-88 doi: 10.1177/089875640602300204
Carmalt JL, Gordon JR, Allen AL.It has been suggested that dental abnormalities lead to temporomandibular joint inflammation and pain that may be mitigated by regular dental care. There is considerable literature on the pathophysiology of equine joint disease including studies on cytokine profiles in diseased appendicular joints. This study examined the effects of age and dental malocclusions summarized as a dental pathology score on equine temporomandibular joint cytokine (IL-1, IL-6, IL-8, TNF alpha and TGF-beta1, -beta2, -beta3) concentrations. TGF-beta3 was not detected in any joint sample. IL-1, IL-6 and TNF alpha were ...
Effect of exercise and suspensory on scrotal surface temperature in the stallion.
Theriogenology    July 31, 2006   Volume 66, Issue 9 2120-2126 doi: 10.1016/j.theriogenology.2006.06.008
Staempfli S, Janett F, Burger D, Kündig H, Imboden I, Hässig M, Thun R.In this study, the effect of exercise (treadmill, riding) on scrotal surface temperature (SST) in the stallion with and without suspensory was evaluated. Experiments were carried out between September and November 2004 using 12 Franches-Montagnes stallions from the National Stud in Avenches (Switzerland). Each stallion performed a standardized incremental treadmill and a ridden test with and without suspensory. The intensity of exercise was monitored by heart rate and blood lactate concentration. For SST measurements, special thermistors were developed and affixed to the most ventral part of t...
Developments in European horse breeding and consequences for veterinarians in equine reproduction.
Reproduction in domestic animals = Zuchthygiene    July 28, 2006   Volume 41, Issue 4 275-279 doi: 10.1111/j.1439-0531.2006.00719.x
Aurich J, Aurich C.The liberalization of European animal breeding legislation and an increasing diversity of equestrian sports have led to a constant rise in the number of horse breeds and breed registries. In addition to the trend towards more and smaller breed registries, there is another trend towards an international expansion of the bigger established sport horse breeds. Regional breeds, at least in smaller countries, may no longer be able to run an independent breeding programme. The typical horse breeder, in the future, will be a female and qualified in equestrian sports. Artificial insemination (AI) main...
Clonidine in horses: identification, detection, and clinical pharmacology.
Veterinary therapeutics : research in applied veterinary medicine    July 28, 2006   Volume 7, Issue 2 141-155 
Dirikolu L, McFadden ET, Ely KJ, ElkHoly H, Lehner AF, Thompson K.Clonidine is classified as a class 3 performance-enhancing agent by the Association of Racing Commissioners International and thus has the potential to influence the outcome of a race. In this study, the authors developed and validated a sensitive gas chromatograph and mass spectrometer method to determine the pharmacokinetic parameters of clonidine in equine plasma samples after IV administration of a single dose (0.025 mg/kg) of clonidine in horses. At this dose, clonidine produced rapid and profound sedation, which cold be quickly reversed with yohimbine. Clonidine was able to produce an an...
Oral hyaluronan gel reduces post operative tarsocrural effusion in the yearling Thoroughbred.
Equine veterinary journal    July 27, 2006   Volume 38, Issue 4 375-378 doi: 10.2746/042516406777749218
Bergin BJ, Pierce SW, Bramlage LR, Stromberg A.Hyaluronan (HA) has been used to treat joint disease via intra-articular, i.v. and oral administration. The efficacy of intra-articular and i.v. use has been evaluated but the oral route has yet to be examined. Objective: To determine the effect of oral hyaluronan gel on joint effusion following arthroscopic surgery for osteochondritis dissecans (OCD) of the tarsocrural joint of yearling Thoroughbreds. Methods: Forty-eight yearlings diagnosed with unilateral or bilateral osteochondritis dessicans (OCD) of the tarsus were arbitrarily chosen prior to arthroscopic surgery. The yearlings were incl...
Measurement of abnormal respiratory sounds during over-ground exercise.
Equine veterinary journal    July 27, 2006   Volume 38, Issue 4 319-323 
Burn JF, Franklin SH.The presence of abnormal respiratory sounds is commonly associated with obstructions of the upper respiratory tract. In order to establish their clinical significance measurements are required of both normal and abnormal respiratory sounds produced by horses exercising over-ground. Objective: To determine whether high quality recordings of respiratory sound can be made during over-ground exercise, and to develop a convenient measurement system that can be used to obtain respiratory sounds from horses exercising in field conditions. Methods: A range of prototypes was evaluated against the requi...
Equine adenovirus 1 infection of hospitalised and healthy foals and horses.
Equine veterinary journal    July 27, 2006   Volume 38, Issue 4 379-381 doi: 10.2746/042516406777749173
Bell SA, Leclere M, Gardner IA, Maclachlan NJ.No abstract available
Correlates between human lung injury after particle exposure and recurrent airway obstruction in the horse.
Equine veterinary journal    July 27, 2006   Volume 38, Issue 4 362-367 doi: 10.2746/042516406777749272
Ghio AJ, Mazan MR, Hoffman AM, Robinson NE.No abstract available
Pharmacokinetics of danofloxacin in horses after intravenous, intramuscular and intragastric administration.
Equine veterinary journal    July 27, 2006   Volume 38, Issue 4 342-346 doi: 10.2746/042516406777749245
Fernández-Varón E, Ayala I, Marín P, Carrión A, Martos N, Escudero E, Cárceles CM.Danofloxacin is a fluoroquinolone developed for veterinary medicine showing an excellent activity. However, danofloxacin pharmacokinetics profile have not been studied in horses previously. Objective: To study the pharmacokinetics following i.v., i.m. and intragastric (i.g.) administration of 1.25 mg/kg bwt danofloxacin to 6 healthy horses. Methods: A cross-over design was used in 3 phases (2 x 2 x 2), with 2 washout periods of 15 days (n = 6). Danofloxacin (18%) was administered by i.v. and i.m. routes at single doses of 1.25 mg/kg bwt. For i.g. administration an oral solution was prepared an...
What is the likelihood that a horse treated for septic digital tenosynovitis will return to its previous level of athletic function?
Equine veterinary journal    July 27, 2006   Volume 38, Issue 4 337-341 doi: 10.2746/042516406777749155
Smith LJ, Mellor DJ, Marr CM, Mair TS.Septic digital tenosynovitis is a serious problem in the horse, with a poor prognosis being reported for recovery. Objective: The occurrence of septic digital tenosynovitis would significantly reduce the likelihood of a horse returning to its previous level of athletic function. Methods: Medical records of 90 horses treated for septic digital tenosynovitis were reviewed. Data retrieved included age, sex, location of inciting cause of sepsis, time from onset of clinical signs to presentation for treatment, and whether the horse survived to be discharged. Long-term outcome was determined through...
Knowledge of the equine temporomandibular joint.
Equine veterinary journal    July 27, 2006   Volume 38, Issue 4 361 
Cook WR.No abstract available
[Influence of animal breeding manner on the occurence of internal parasites].
Wiadomosci parazytologiczne    July 27, 2006   Volume 50, Issue 3 647-651 
Romaniuk K, Reszka K, Lasota E.On the turn of July and August the prevalence and intensity of internal parasites of cattle, deer, and primitive Polish horses were estimated. It was determined, that all groups of animals were infected with parasites. The prevalence and intensity of infection were diversified and depended on the animal species, breed, age, and even sex. For instance, dairy cows of lowland black-and-white breed were six times stronger infected than Polish red breed, despite using the same pasture and the same cowshed. Nematodes and coccidia were present in calves using small, frequently wet, calf-runs and at h...
Risk factors for colic in horses after general anaesthesia for MRI or nonabdominal surgery: absence of evidence of effect from perianaesthetic morphine.
Equine veterinary journal    July 27, 2006   Volume 38, Issue 4 368-374 doi: 10.2746/042516406777749263
Andersen MS, Clark L, Dyson SJ, Newton JR.Post anaesthetic colic is a recognised risk of general anaesthesia (GA), but causes are poorly understood. Objective: To identify risk factors for development of colic following GA for magnetic resonance imaging (MRI) or nonabdominal surgery and to test whether the use of perianaesthetic morphine was associated with an increased risk of post anaesthetic colic. Methods: A total of 553 anaesthetic and clinical records of 500 horses anaesthetised at the Animal Health Trust were analysed, 342 (62%) involved MRI and 211 (38%) nonabdominal, predominantly orthopaedic surgery. Multivariable logistic r...
Prevalence of gastric squamous ulceration in horses with abdominal pain.
Equine veterinary journal    July 27, 2006   Volume 38, Issue 4 347-349 doi: 10.2746/042516406777749164
Dukti SA, Perkins S, Murphy J, Barr B, Boston R, Southwood LL, Bernard W.Prevalence of gastric ulcerations differs widely according to breed and circumstances of management. Further study of the biological variables involved is required in order to identify more exactly the reasons for the reported range. Objective: The objectives of this present study, which do not appear to have been addressed previously in the literature, were 1) the prevalence of gastric ulceration in horses with abdominal pain. 2) difference in prevalence in horses responding to medical therapy and those requiring surgical intervention. 3) whether gastric ulceration is associated with any part...