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Topic:Veterinary Medicine

Veterinary medicine for horses encompasses the study and application of medical practices to diagnose, treat, and prevent diseases in equine species. This field involves a comprehensive understanding of equine anatomy, physiology, pathology, and pharmacology. Veterinary practitioners employ a range of diagnostic tools and therapeutic interventions to address health issues in horses, including lameness, gastrointestinal disorders, respiratory conditions, and infectious diseases. Preventative care, such as vaccination and deworming programs, is also a significant aspect of equine veterinary medicine. This page gathers peer-reviewed research studies and scholarly articles that explore various aspects of veterinary medicine as it pertains to horses, including advancements in diagnostic techniques, treatment protocols, and preventive health strategies.
Incidence of polysaccharide storage myopathy: necropsy study of 225 horses.
Veterinary pathology    November 23, 2005   Volume 42, Issue 6 823-827 doi: 10.1354/vp.42-6-823
Valentine BA, Cooper BJ.Muscle samples were obtained at necropsy from 225 horses and ponies 1 year of age or older. Samples were processed in routine manner and were stained with hematoxylin and eosin and with periodic acid-Schiff for glycogen. Sections were examined for abnormal glycogen content and amylase-resistant complex polysaccharide and for chronic myopathic change (excessive fiber size variation, increase in number of internal nuclei). A total of 101 horses and ponies with lesions of polysaccharide storage myopathy were identified. Age of affected horses ranged from one to 30 years, with a mean of 14.7 years...
A modified critical test and its use in two dose titration trials to assess efficacy of praziquantel for Anoplocephala perfoliata in equids.
Veterinary parasitology    November 23, 2005   Volume 136, Issue 2 127-135 doi: 10.1016/j.vetpar.2005.10.025
Slocombe JO.Aims of this study with 43 equids naturally infected with Anoplocephala perfoliata in two dose titration trials were to document (i) the usefulness of a critical test with a 48 h treatment to necropsy period, (ii) efficacy of an oral paste of 0.5-2.0 mg praziquantel/kg body weight, and (iii) when after treatment would fecal egg counts provide best estimates of the tapeworm's prevalence in a herd. All feces passed by an equid after treatment and collected in successive 12 h batches were examined for tapeworms. At necropsy, tapeworms were identified as attached to the mucosa or unattached. Tapew...
Prescription-only anthelmintics–a questionnaire survey of strategies for surveillance and control of equine strongyles in Denmark.
Veterinary parasitology    November 23, 2005   Volume 135, Issue 1 47-55 doi: 10.1016/j.vetpar.2005.10.020
Nielsen MK, Monrad J, Olsen SN.In 1999, legislation in Denmark made anthelmintic drugs available only by prescription, and prohibited their use for routine, prophylactic treatment. A questionnaire survey was conducted in 2004 to determine current strategies for surveillance and control of equine strongyles used in Danish equine veterinary practices. Eighty-seven of 170 (51.2%) registered equine veterinary practices responded. Ninety seven percent of the respondents used faecal egg counts for diagnosis and surveillance, and 41% used larval cultures. Logistic regression revealed that the use of larval cultures was positively ...
Skeletal muscle blood flow in anaesthetized horses. Part II: effects of anaesthetics and vasoactive agents.
Veterinary anaesthesia and analgesia    November 22, 2005   Volume 32, Issue 6 331-337 doi: 10.1111/j.1467-2995.2005.00192.x
Raisis AL.This review aims at evaluating studies investigating the effects of anaesthesia on skeletal muscle blood flow and associated cardiovascular function in anaesthetized horses and discusses how the results of these studies contribute to our understanding of the pathogenesis and prevention of post-anaesthetic myopathy. Methods: Pubmed & personal files. Conclusions: There is little published information on the effects of anaesthesia on skeletal muscle blood flow in horses. Available reports predominantly refer to halothane and isoflurane. The effects of vasoactive drugs have mainly been studied...
Effect of repeated oral administration of hypertonic electrolyte solution on equine gastric mucosa.
Equine veterinary journal    November 22, 2005   Volume 37, Issue 6 501-504 doi: 10.2746/042516405775314880
Holbrook TC, Simmons RD, Payton ME, MacAllister CG.Electrolyte supplementation is common in horses during endurance competitions, but the effect on the gastric mucosa is unknown. Objective: Repeated oral administration of hypertonic electrolyte solution is associated with exacerbation of gastric ulcers in mature horses. Methods: The study design was a randomised, blinded, crossover trial. Fourteen horses were divided randomly into equal groups and administered either 60 ml water (placebo) or 56.7 g commercial electrolyte supplement mixed with 60 ml water by dose syringe orally once an hour for 8 h. The minimum concentration of individual const...
Extracorporeal shock wave therapy for treatment of osteoarthritis in the horse: clinical applications.
The Veterinary clinics of North America. Equine practice    November 22, 2005   Volume 21, Issue 3 609-vi doi: 10.1016/j.cveq.2005.09.001
Revenaugh MS.Veterinarians have begun using extracorporeal shock wave therapy (ESWT) for treatment of osteoarthritis (OA) in horses, although relatively little information has been published about its efficacy or mechanism of action. As a clinician, it can be difficult to know if and when ESWT should be recommended. Case studies in which ESWT is used to treat advanced OA in horses are discussed. ESWTseems to be a valuable adjunct for management of equine OA. It is the purpose of this article to discuss indications and techniques as well as to share clinical experiences using ESWT in the treatment of OA in ...
High inspired oxygen concentrations increase intrapulmonary shunt in anaesthetized horses.
Veterinary anaesthesia and analgesia    November 22, 2005   Volume 32, Issue 6 338-347 doi: 10.1111/j.1467-2995.2005.00199.x
Marntell S, Nyman G, Hedenstierna G.To compare pulmonary function and gas exchange in anaesthetized horses during and after breathing either O2-rich gas mixtures or air. Methods: Six healthy standard bred trotters (age range 3-12 years; mass range 423-520 kg), four geldings and two mares. Study design Randomized, cross-over experimental study. Methods: Horses were anaesthetized on two occasions with tiletamine-zolazepam after pre-anaesthetic medication with acepromazine, romifidine and butorphanol. After endotracheal intubation and positioning in left lateral recumbency, animals were allowed to breathe spontaneously. One of two,...
MRSA: an emerging equine problem?
Equine veterinary journal    November 22, 2005   Volume 37, Issue 6 490-492 doi: 10.2746/042516405775314790
Slater JD.No abstract available
New surgical treatments for osteochondritis dissecans and subchondral bone cysts.
The Veterinary clinics of North America. Equine practice    November 22, 2005   Volume 21, Issue 3 673-vii doi: 10.1016/j.cveq.2005.07.005
Fortier LA, Nixon AJ.Osteochondritis dissecans (OCD) and subchondral bone cysts (SBCs) occur commonly and at many different locations in equine limbs and can lead to secondary osteoarthritis when left untreated. Depending on the location and extent of the lesion, arthroscopic surgical debridement may be an effective treatment for returning a horse to athletic soundness. In many cases, however, additional techniques to improve the healing response in bone and cartilage are needed so as to preserve articular function. Methods for improving cartilage repair (ie, restoration of damaged cartilage)or regeneration (ie, r...
Use of serum amyloid A and other acute phase reactants to monitor the inflammatory response after castration in horses: a field study.
Equine veterinary journal    November 22, 2005   Volume 37, Issue 6 552-556 doi: 10.2746/042516405775314853
Jacobsen S, Jensen JC, Frei S, Jensen AL, Thoefner MB.Early recognition of excessive inflammation and infectious complications after surgery, leading to early institution of therapy, reduces post operative discomfort and facilitates recovery. Because serum amyloid A (SAA) is a highly sensitive marker of inflammation, measurements of SAA and other acute phase reactants in the equine surgical patient may be valuable in assisting clinical assessment of post operative inflammation. Objective: To investigate changes in inflammatory markers after castration and to correlate levels of acute phase reactants with clinical severity of inflammation after ca...
Equine rehabilitation therapy for joint disease.
The Veterinary clinics of North America. Equine practice    November 22, 2005   Volume 21, Issue 3 599-vi doi: 10.1016/j.cveq.2005.08.002
Porter M.The principles of physical rehabilitation therapy can be applied to the horse to provide a reduction in discomfort and dysfunction associated with the various forms of joint disease. Physical agents,such as ice, heat, electricity, sound, light, magnetic fields, compression, and movement, can be used by the rehabilitation therapist to attempt to control pain, reduce swelling, and restore optimal movement and function in the affected joint. The equine therapist's attention is focused not only on the affected joint but on the body as a whole to manage secondary or compensatory problems.
Skeletal muscle blood flow in anaesthetized horses. Part I: measurement techniques.
Veterinary anaesthesia and analgesia    November 22, 2005   Volume 32, Issue 6 324-330 doi: 10.1111/j.1467-2995.2005.00191.x
Raisis AL.The objective of this review was to describe the methodology and limitations of techniques that have been used to measure skeletal muscle blood flow in anaesthetized horses. Methods: Pubmed, personal files. Conclusions: Numerous techniques have been used in horses to study skeletal muscle blood flow during anaesthesia and after the administration of vasoactive agents. Of the available techniques, blood flow measurements are limited to either microvascular flow (radioactive xenon, laser Doppler flowmetry) or total blood flow (radioactive microspheres, electromagnetic flowmetry, Doppler ultrason...
Black walnut extract-induced laminitis in horses is associated with heterogeneous dysfunction of the laminar microvasculature.
Equine veterinary journal    November 22, 2005   Volume 37, Issue 6 546-551 doi: 10.2746/042516405775314781
Peroni JF, Harrison WE, Moore JN, Graves JE, Lewis SJ, Krunkosky TM, Robertson TP.Equine laminitis purportedly involves haemodynamic dysfunction at the level of the laminar vasculature. However, to date, no studies have been performed characterising the function of laminar arteries and veins during the prodromal stages of equine laminitis. Objective: That the prodromal stages of laminitis are associated with contractile dysfunction of the equine laminar vasculature. Objective: To assess contractile function of laminar arteries and veins to phenylephrine (PE) and 5-hydroxytryptamine (5-HT). Methods: Horses were administered black walnut heartwood extract (BWHE) or water (con...
Total intravenous anaesthesia in horses using medetomidine and propofol.
Veterinary anaesthesia and analgesia    November 22, 2005   Volume 32, Issue 6 348-354 doi: 10.1111/j.1467-2995.2005.00202.x
Bettschart-Wolfensberger R, Kalchofner K, Neges K, Kästner S, Fürst A.To examine the clinical suitability of medetomidine-propofol infusions for total intravenous anaesthesia in horses. Methods: Fifty client-owned horses of mixed breed, age [mean +/- SD (range)] 6.6 +/- 4.4 (0.04-18) years, mass 478 +/- 168.3 (80-700) kg presented for a range of operations requiring general anaesthesia. Methods: Pre-anaesthetic medication was intravenous (IV) medetomidine 7 mug kg(-1). Anaesthesia was induced with IV ketamine (2 mg kg(-1)) and diazepam (0.02 mg kg(-1)). After endotracheal intubation, O2 was delivered (FiO2 > 0.85). Positive pressure ventilation was initiated if ...
Scintigraphic, radiographic, and thermographic appearance of the metacarpal and metatarsal regions of adult healthy horses treated with nonfocused extracorporeal shock wave therapy–a pilot study.
Veterinary therapeutics : research in applied veterinary medicine    November 22, 2005   Volume 6, Issue 3 268-276 
Verna M, Turner TA, Anderson KL.Nonfocused extracorporeal shock wave therapy (ESWT) treatment protocol is commonly used in veterinary practice. This study investigated the effects of four nonfocused ESWT treatments, given 2 weeks apart, on bone radiopharmaceutical uptake and radiographic and thermographic appearance in the metacarpal and metatarsal regions in six adult untrained horses. There were no measurable treatment effects determined by thermography (daily), scintigraphy (at 2-week intervals), and radiography (before study initiation and at study completion) between treated and control limbs. It was concluded that no g...
Changes in steady-state concentrations of messenger ribonucleic acids in luteal tissue during prostaglandin F2alpha induced luteolysis in mares.
Animal reproduction science    November 22, 2005   Volume 90, Issue 3-4 273-285 doi: 10.1016/j.anireprosci.2005.02.008
Beg MA, Gastal EL, Gastal MO, Ji S, Wiltbank MC, Ginther OJ.Transvaginal ultrasound-guided luteal biopsy was used to evaluate the effects of prostaglandin (PG)F2alpha on steady-state concentrations of mRNA for specific genes that may be involved in regression of the corpus luteum (CL). Eight days after ovulation (Hour 0), mares (n=8/group) were randomized into three groups: control (no treatment or biopsy), saline+biopsy (saline treatment at Hour 0 and luteal biopsy at Hour 12), or PGF2alpha+biopsy (5mg PGF2alpha at Hour 0 and luteal biopsy at Hour 12). The effects of biopsy on CL were compared between the controls (no biopsy) and saline+biopsy group. ...
Closing in on the equine joint.
Equine veterinary journal    November 22, 2005   Volume 37, Issue 6 493-494 doi: 10.2746/042516405775314907
van Weeren PR, Nixon AJ.No abstract available
Cross-sectional anatomy and comparative ultrasonography of the equine medial femorotibial joint and its related structures.
Equine veterinary journal    November 22, 2005   Volume 37, Issue 6 520-529 doi: 10.2746/042516405775314817
Hoegaerts M, Nicaise M, Van Bree H, Saunders JH.Injuries of the equine stifle are frequent causes of hindlimb lameness. Ultrasonography is useful for the diagnosis of many soft tissue lesions but, until recently, its application to the equine stifle has been limited to a description of normal and abnormal structures. A comparative study using gross anatomical sections to identify all structures visible on ultrasonographic images of the equine stifle has not previously been reported. Objective: To provide a comprehensive comparative cross-sectional atlas of the normal equine medial femorotibial (MFT) joint and its related structures using ul...
Attempted eradication of methicillin-resistant staphylococcus aureus colonisation in horses on two farms.
Equine veterinary journal    November 22, 2005   Volume 37, Issue 6 510-514 doi: 10.2746/042516405775314835
Weese JS, Rousseau J.Methicillin-resistant Staphylococcus aureus (MRSA) is an emerging equine and zoonotic pathogen. Infection control protocols can be used to control MRSA in human hospitals, but measures to eradicate MRSA on horse farms have not been evaluated. Objective: To describe an MRSA eradication programme that was used to attempt to eliminate MRSA colonisation among horses and horse personnel on 2 equine farms. Methods: Active surveillance cultures and infection control protocols were implemented on 2 farms with endemic MRSA. Results: Active screening and strict implementation of infection control protoc...
Effect of acupuncture, electroacupuncture and Panax pseudoginseng on blood coagulation variables in horses.
The Veterinary record    November 22, 2005   Volume 157, Issue 21 662-664 doi: 10.1136/vr.157.21.662
Angeli AL, Joaquim JG, Takahira RK, Bulla C, Luna SP.No abstract available
Arthrodesis techniques in horses.
The Veterinary clinics of North America. Equine practice    November 22, 2005   Volume 21, Issue 3 691-vii doi: 10.1016/j.cveq.2005.07.004
Zubrod CJ, Schneider RK.When medical therapy and surgical treatments of an injured joint fail to return the animal to athletic performance or comfortable use of the limb, arthrodes is is a final option for some joints. Arthrodesis refers to the surgical fusion of a joint, resulting in bony ankylosis. Successful arthrodesis requires debridement of the articular cartilage through the calcified cartilage layer, exposing the subchondral bone; alignment of the joint into a weight-bearing position; and stabilization. The methods by which these steps are accomplished are variable, depending on the individual joint. There ar...
Behavioural assessment of pain in horses and donkeys: application to clinical practice and future studies.
Equine veterinary journal    November 22, 2005   Volume 37, Issue 6 565-575 doi: 10.2746/042516405775314826
Ashley FH, Waterman-Pearson AE, Whay HR.No abstract available
Role of transcranial magnetic stimulation in differentiating motor nervous tract disorders from other causes of recumbency in four horses and one donkey.
The Veterinary record    November 22, 2005   Volume 157, Issue 21 656-658 doi: 10.1136/vr.157.21.656
Nollet H, Vanschandevijl K, Van Ham L, Vanderstraeten G, Deprez P.Transcranial magnetic stimulation and measurement of the magnetic motor-evoked potentials (MMEPs) in the thoracic and pelvic limbs of four recumbent horses and one recumbent donkey were used to assess the integrity of the descending motor pathways, in order to confirm or exclude a descending motor tract lesion as the cause of the recumbency. In two of the animals abnormal MMEPs were recorded; in one of the horses a lesion along the cervical spinal cord due to a fracture of the fifth cervical vertebra was diagnosed and confirmed by radiography and postmortem examination; in another horse, damag...
Detection of equine herpesvirus type 1 by real time PCR.
Journal of virological methods    November 22, 2005   Volume 133, Issue 1 70-75 doi: 10.1016/j.jviromet.2005.10.024
Elia G, Decaro N, Martella V, Campolo M, Desario C, Lorusso E, Cirone F, Buonavoglia C.A real-time PCR assay was developed for detection and quantitation of equid herpesvirus type 1 (EHV-1). The sensitivity of the assay was compared with an established nested-PCR (n-PCR). The real-time PCR detected 1 copy of target DNA, with a sensitivity 1 log higher than gel-based n-PCR. The assay was able to detect specifically EHV-1 DNA in equine tissue samples and there was no cross-amplification of other horse herpesviruses. Real-time PCR was applied to determine EHV-1 load in tissue samples from equine aborted fetuses. The high sensitivity and reproducibility of the EHV-1-specific fluorog...
Diagnosis and treatment of ligamentous and meniscal injuries in the equine stifle.
The Veterinary clinics of North America. Equine practice    November 22, 2005   Volume 21, Issue 3 651-vii doi: 10.1016/j.cveq.2005.08.003
Walmsley JP.The accuracy of the diagnosis of ligamentous and meniscal injuries in the equine stifle has improved significantly in the last 20 years. There are, however, significant limitations in the diagnosis of stifle injuries because of the size and anatomy of the equine stifle. Treatment of soft tissue injuries to the equine stifle has been empirical,with only a few large case studies for specific conditions of stifle ligaments and menisci and only retrospective case studies of the outcome of treatment. This article describes the diagnosis and treatment of ligamentous and meniscal injuries in the equi...
Effect of a constant rate infusion of lidocaine on the quality of recovery from sevoflurane or isoflurane general anaesthesia in horses.
Equine veterinary journal    November 22, 2005   Volume 37, Issue 6 559-564 doi: 10.2746/042516405775314772
Valverde A, Gunkelt C, Doherty TJ, Giguère S, Pollak AS.Lidocaine constant rate infusions (CRIs) are common as an intraoperative adjunct to general anaesthesia, but their influence on quality of recovery has not been thoroughly determined. Objective: To determine the effects of an intraoperative i.v. CRI of lidocaine on the quality of recovery from isoflurane or sevoflurane anaesthesia in horses undergoing various surgical procedures, using a modified recovery score system. Objective: The administration of intraoperative lidocaine CRI decreases the quality of recovery in horses. Methods: Lidocaine (2 mg/kg bwt bolus followed by 50 microg/kg bwt/min...
Two clinical manifestations of desmopathy of the accessory ligament of the deep digital flexor tendon in the hindlimb of 23 horses.
Equine veterinary journal    November 22, 2005   Volume 37, Issue 6 495-500 doi: 10.2746/042516405775314871
Eliashar E, Dysont SJ, Archer RM, Singer ER, Smith RK.Desmopathy of the accessory ligament of the deep digital flexor tendon (ALDDFT) in the hindlimb is an unusual cause of lameness in horses, and reports of the condition are sparse. Objective: To describe the clinical and ultrasonographic findings, therapy and outcome of 23 horses treated for desmopathy of the ALDDFT in the hindlimb. Methods: Records of 23 horses with ultrasonographic evidence of desmopathy of the ALDDFT in one or both hindlimbs from 3 referral centres were reviewed retrospectively. Age, breed, sex, duration and nature of clinical signs, results of clinical and lameness examinat...
The use of nutraceuticals for osteoarthritis in horses.
The Veterinary clinics of North America. Equine practice    November 22, 2005   Volume 21, Issue 3 575-vi doi: 10.1016/j.cveq.2005.08.004
Trumble TN.In horses, lameness is often attributable to some degree of osteoarthritis (OA), a complex disease process that is highlighted by eventual degradation of articular cartilage. Conventional therapies for OA in horses are designed to relieve pain and discomfort and often include pharmacologic intervention with nonsteroidal anti-inflammatory drugs or intra-articular steroids. Oral administration of nutraceutical products to the horse is common and easy and is perceived to be a benign treatment for OA in horses. The main goal for use of nutraceuticals is to use them in OA cases to attempt to lower ...
Future directions in treatment of joint disease in horses.
The Veterinary clinics of North America. Equine practice    November 22, 2005   Volume 21, Issue 3 713-viii doi: 10.1016/j.cveq.2005.07.001
Frisbie DD.Osteoarthritis is one of the most economically important diseases facing equine practitioners. The loss of use associated with joint disease is a leading problem in the equine industry. Although osteoarthritis in all species is believed to be a multifactorial disease that is not well understood, significant advances are being made. This article presents areas of research that are relatively well developed but have not made it to commercialization or routine clinical practice and looks at new applications being investigated for peo-ple that may have an equine application.
Radiographic scoring lacks predictive value in inflammatory airway disease.
Equine veterinary journal    November 22, 2005   Volume 37, Issue 6 541-545 doi: 10.2746/042516405775314899
Mazan MR, Vin R, Hoffman AM.Diagnosis of inflammatory airway disease (IAD) currently rests upon the results of bronchoalveolar lavage (BAL) cytology, lung function testing and histamine bronchoprovocation (HBP), none of which provides direct information about structural change in the lung. Objective: That thoracic radiography might better portray structural change in the lungs and therefore offer a good clinical assessment of IAD. Methods: A radiographic scoring system was developed to assess the extent of bronchial and interstitial pattern on thoracic radiographs in the dorsocaudal, dorsocranial and caudoventral regions...