Veterinary practice in relation to horses encompasses the medical care, management, and treatment of equine species. This field involves various aspects of equine health, including preventive care, diagnosis, and treatment of diseases, surgical interventions, and emergency care. Equine veterinarians employ a range of diagnostic tools and techniques such as physical examinations, imaging, and laboratory tests to assess and monitor horse health. In addition to addressing physical ailments, veterinary practice also includes nutritional management, reproductive health, and performance-related issues. This page compiles peer-reviewed research studies and scholarly articles that explore the methodologies, advancements, and outcomes in veterinary practices specific to equine health.
Bladon BM, Hillyer MH.Extensive resection of the ileum of the horse, using automated stapling equipment followed by a stapled jejunocaecostomy, without closure of the mesenteric defect, was evaluated prospectively as a surgical treatment for lesions involving the distal small intestine. Of 153 horses treated surgically for colic, 10 horses with strangulating lesions involving the distal ileum were treated by extensive resection and jejunocaecal anastomosis leaving a residual mesenteric defect. These were compared with 12 horses with jejunoileal lesions treated by jejunocaecal anastomosis with closure of the mesente...
Hardy J, Minton M, Robertson JT, Beard WL, Beard LA.The clinical findings and outcome of 161 horses diagnosed with 174 episodes of nephrosplenic entrapment (NSE) were reviewed retrospectively. The median age at presentation was 5 years (9 months to 24 years), and duration of colic was 2-92 h. Nasogastric reflux was present in 49 of 113 horses (43.4%) and was significant (> or = 21) in 32 (28.3%) horses. The recurrence rate was 13/161 (8.1%). Thirteen horses (13/174, 7.5%) had other lesions including small intestinal obstruction (4), 360 degrees large colon torsion (5), gastric rupture (2), thromboembolic colic (1) and small colon infarction (1)...
Mair TS.Eight horses with Grade 3b rectal tears of the peritoneal part of the rectum or small colon were treated by a combination of medical therapy and dietary manipulation. All of the horses developed septic peritonitis during the course of treatment. Medical therapy consisted of a combination of penicillin, gentamicin and flunixin meglumine administered parenterally, metronidazole administered orally and liquid paraffin administered by nasogastric tube. Some horses also received fluid and electrolyte therapy i.v., plasma and heparin i.v. All horses were maintained on a laxative diet. Six of the 8 h...
Thoefner MB, Ersbøll AK, Hesselholt M.A prospective survey of 528 colic horses, referred to the Large Animal Hospital at the Royal Veterinary and Agricultural University of Copenhagen, Denmark, during the period August 1994 to December 1998, was undertaken to develop a predictive model for application in the clinical assessment of prognosis. In the multivariate logistic regression analysis, 357 colic cases were used in the elaboration of a simple clinical-practical model consisting of degree of pain, packed cell volume, capillary refill time and rectal temperature. The relationship between rectal temperature and outcome (survival/...
Thoefner MB, Ersbøll AK, Jensen AL, Hesselholt M.A prospective survey of horses with colic referred to the Large Animal Hospital at the Royal Veterinary and Agricultural University of Copenhagen, Denmark, was undertaken between August 1994 and December 1997. The interrelationships between 17 clinical variables were analysed using factor analysis. Factor analysis uncovers the structure of the variability in data and therefore detects multicollinearity. A total of 528 horses were admitted in the study period. Of these, 16 were excluded from the analysis as a result of miscellaneous conditions. Only 205 horses had observations for all 17 variab...
Hannah HW.This research study discusses the effectiveness of liens for veterinary services, exploring different court cases that define and interpret possessory and non-possessory liens in veterinary contexts. The article highlights the […]
Natalini CC, Robinson EP.To evaluate and compare effects of epidurally administered morphine, alfentanil, butorphanol, tramadol, and U50488H on avoidance threshold to noxious electrical stimulation over the dermatomes of the perineal, sacral, lumbar, and thoracic regions in horses. Methods: 5 healthy adult horses. Methods: Using a Latin square complete repeated-measures design, horses were randomly assigned to receive 1 of 6 treatments (morphine, alfentanil, butorphanol, tramadol, U50488H, or sterile water) at intervals of at least 7 days. Agents were injected epidurally at the first intercoccygeal epidural space, and...
Freeman SL, England GC.The effects of two intravenous doses of romifidine (80 and 120 microg/kg) and one dose of detomidine (20 microg/kg) were compared in a blinded study in 30 horses requiring to be sedated for routine dental treatment. Several physiological parameters were assessed before and for two hours after the administration of the drugs, and the horses' teeth were rasped 30 minutes after they were administered. Romifidine produced a dose-dependent effect on most parameters. Detomidine at 20 microg/kg was similar to romifidine at 120 microg/kg in the magnitude of its sedative effects, but was similar to rom...
Blackford J, Doherty TJ, Ferslew KE, Panus PC.In human rehabilitation medicine, dexamethasone-phosphate is theoretically iontophoresed to localized subcutaneous tissue where conversion to dexamethasone occurs. This delivery system has recently been introduced into veterinary medicine for the same purpose. However, the pharmacokinetic justification for parenteral delivery of this prodrug remains undocumented. Utilizing iontophoretic methods that are relevant to both human and veterinary clinical practice, the present investigation compared injection and iontophoresis of dexamethasone-phosphate into the equine tibiotarsal joint, also known ...
Dowling BA, Dart AJ, Hodgson DR.A 2-week-old Miniature Horse foal was referred for evaluation and treatment of a luxated right tarsometatarsal joint. Treatment consisted of closed reduction and internal fixation using two partially threaded Steinmann pins placed in normograde fashion through the tuber calcis into the proximal third metatarsus. Traumatic luxation has been reported to occur in the tarsocrural, proximal intertarsal and tarsometatarsal joints within the equine tarsus. Treatment for luxation of the distal intertarsal joint has not been documented. The treatment method most commonly suggested for tarsal luxation i...
Verheyen K, Newton JR, Talbot NC, de Brauwere MN, Chanter N.Three protracted outbreaks of strangles were investigated using endoscopic examination and a total of 14 asymptomatic carriers of Streptococcus equi were identified of which 13 showed evidence of carriage in the guttural pouch. Treatment was initiated to eliminate S. equi colonisation since these animals posed an infectious risk to susceptible horses. Two further horses were referred to us with severe guttural pouch pathology and from which S. equi was cultured, and treatment of these cases is also described. Treatment in the first instance was directed towards removal of gross guttural pouch ...
Neuwirth L, Romine C.The construction of ancillary equipment used to improve image quality and reduce personnel radiation exposure in the equine nuclear medicine laboratory is illustrated. The devices include a self supporting lead sheet for shielding the distal limb or limb pair, a hanging lead sheet for shielding the proximal limb, a lead square for shielding the urinary bladder or jugular catheter, a restraining board for acquiring a palmar view of the foot, a head support to stabilize the head for imaging and a head support for stabilizing the neck for imaging. The restraining board and head supports decrease ...
Behn C, Bostedt H.Under field conditions, the diagnosis of foal's diseases relies almost exclusively on the physical examination. As the signs of illness in the equine neonate are frequently vage and non-localizing, the diagnosis of diseases may be problematic. This often causes misinterpretations and leads to ineffective prophylaxis and treatment. The purpose of this study was to evaluate the usefulness of diagnostic ultrasonography of the foal's abdomen under field conditions to provide an optimized technique and to describe the normal findings. Diagnostic ultrasonography of the abdomen was performed after ob...
Saville WJ, Morley PS, Reed SM, Granstrom DE, Kohn CW, Hinchcliff KW, Wittum TE.To investigate risk factors for use in predicting clinical improvement and survival of horses with equine protozoal myeloencephalitis (EPM). Methods: Longitudinal epidemiologic study. Methods: 251 horses with EPM. Methods: Between 1992 and 1995, 251 horses with EPM were admitted to our facility. A diagnosis of EPM was made on the basis of neurologic abnormalities and detection of antibody to Sarcocystis neurona or S neurona DNA in CSF. Data were obtained from hospital records and through telephone follow-up interviews. Factors associated with clinical improvement and survival were analyzed, us...
Bienzle D, Stanton JB, Embry JM, Bush SE, Mahaffey EA.To compare CBC results obtained by use of an in-house centrifugal analyzer with results of a reference method. Methods: Prospective study. Methods: Blood samples from 147 dogs, 42 cats, and 60 horses admitted to a veterinary teaching hospital and from 24 cows in a commercial dairy herd. Methods: Results obtained with the centrifugal analyzer were compared with results obtained with an electrical-impedance light-scatter hematology analyzer and manual differential cell counting (reference method). Results: The centrifugal analyzer yielded error messages for 50 of 273 (18%) samples. Error message...
Collard XR, Danse EM, Rombouts JJ.The treatment of acute complete (grade III) tears of the lateral ligaments of the ankle has generated much controversy in the medical literature. Functional treatment has become the standard treatment as it has been shown that there is no significant difference in long term results whatever the treatment (operative repair and cast, cast alone, or early controlled mobilization). Functional treatment includes only a short period of protection by tape bandage or brace and allows early weight-bearing. Major trauma with avulsion of bone and severe ligamentous damage on both medial and lateral sides...
van den Wollenberg L, Pellicaan CH, Müller K.Two horses were accidentally administered propylene glycol instead of mineral oil. After discovery of the mistake intensive medical therapy with intravenous fluids, etc. was started, and both animals recovered fully from their clinical symptoms. Veterinarians use propylene glycol as well as paraffin routinely for the treatment of their patients. Mistakes are likely to be made because both medicines and sometimes their packing have a similar appearance. Several incidents have been reported in other countries. A large amount of propylene glycol given to a horse, but also to other animals, can be...
Bassage LH, Garcia-Lopez J, Currid EM.Two adult horses were evaluated for chronic hind limb lameness. Nonseptic calcanean bursitis with associated focal osteolytic lesions at the point of insertion of the gastrocnemius tendon was diagnosed in each horse by physical and lameness examinations, radiography, ultrasonography, and synovial fluid analysis. Both horses underwent arthroscopic exploration and lavage of the affected bursa, and one horse also underwent surgical debridement of the osseous lesion. Both horses remained lame for 13 months after the surgical procedures. To our knowledge, osseous lesions of the calcaneus in horses ...
This section includes clinical conditions which have unique characteristics which make them unsuitable for inclusion in the first six sections. The clinical description, aetiology and histopathologic findings of the unusual ear lesion, aural plaques, are described. Dermatoses complicated by, or caused by, photosensitivity are discussed in regards to their aetiology and pathogenesis as well as clinical features. The suggestion that photosensitization plays a role in the development of the lesions seen in pastern leukocytoclastic vasculitis is made. This section ends with an in depth discussion ...
Ragle CA.Laparoscopic cystotomy is the method of choice for treatment of a cystic calculus in the horse. The main advantage of this procedure over others is the excellent ability to view and gain operative access to the urinary bladder. This article describes the procedure, including techniques, instrumentation, preoperative and postoperative care, and complications.
Lejeune JP, Schneider N, Caudron I, Duvivier DH, Serteyn D.Ossification of collateral cartilages is a common radiographic finding in draught horses and indication of a high frequency of interphalangeal osteo-arthropathy have been found in Ardenner horses. This study first aimed at following the evolution of the digits of the forelimbs on radiographic images in a group of 32 Ardenner horses from weaning to 852 +/- 19 days and, secondly, at evaluating the clinical significance of the observed radiographic changes. At 250 +/- 21 days, only 23% of the horses presented a small separate ossification centre of collateral cartilages above the level of the dis...
Caldwell FJ, Waguespack RW.To develop a tenoscopic approach for desmotomy of the accessory ligament of the deep digital flexor tendon (AL-DDFT) in horses. Methods: Experimental. Methods: Cadaveric forelimbs (n=10) and 4 forelimbs from 2 horses anesthetized for terminal teaching procedures, and 12 forelimbs of 6 experimental horses. Methods: Saline distention of the carpal flexor sheath facilitated insertion of an arthroscope into the distal medial aspect of the sheath between the AL-DDFT and deep digital flexor tendon (DDFT). Location of an instrument portal on the lateral aspect of the metacarpus was identified with a ...
Fregin GF.The approach to pre-purchase evaluation of the equine cardiovascular system is discussed with emphasis on cardiac auscultation and on the terminology that should be used when reporting clinical findings. Innocent cardiac murmurs and arrhythmias are contrasted with those that should be considered as reliable signs of cardiovascular disease. Ultrasonography and electrocardiography are recommended to establish baseline values for future reference, to support opinions rendered by the examining veterinarians, or to provide for diagnosis and treatment.
Feng KR.A method of electro-acupuncture for treatment of intestinal impaction of the horse was reported. The unique technique of the treatment includes deep needle insertion and the "triple tetanic treatment." Possible mechanism of this form of treatment was discussed.
Schumacher J, DeGraves FJ, Spano JS.The clinical and clinicopathologic effects of raw linseed oil and mineral oil were compared. In a crossover experimental design trial, 6 horses were given either raw linseed oil (2.5 mL/kg body weight) or mineral oil (10 mL/kg body weight), twice, 12 hours apart. Two weeks later, the horses received the opposite treatment. All horses given mineral oil or linseed oil developed nonformed feces by 24 hours of the first administration of oil. Horses treated with mineral oil had formed feces at 48 hours; horses treated with linseed oil developed normally formed feces at 96 to 108 hours. All horses ...
Belotta AF, Mayer MN, Waldner CL, Robinson K, Sidhu N, Carmalt J, Bell CD, Koehncke NK.The objective of this study was to report observed radiation safety practices among equine workers using portable X-ray units at 3 veterinary practices in Canada. Practice 1 was comprised of equine field service workers from an academic institution, whereas Practices 2 and 3 were comprised of workers from private equine referral practices. Out of 2969 exposure-worker observations, protective aprons were worn for > 99% (2968/2969), thyroid shields for 87% (2584/2969), and eyeglasses for 10% (310/2969). The cassette was held by hand for 97% (1078/1114) of observations, and the X-ray unit was ...
Sellon DC, Sanz M, Kopper JJ.Little is known about the acquisition and use of equine analgesic drugs by horse owners in the United States (US). Objective: To determine factors associated with possession of analgesic drugs by horse owners in the US or with analgesic drug acquisition from sources noncompliant with a valid veterinarian-client-patient (VCPR) relationship. Methods: Cross-sectional survey. Methods: An internet-based questionnaire included items related to experiences with horses and equine analgesic drugs. Factors associated with possession of ≥5 types of analgesic drugs and with the acquisition of drugs from...
Kleijn WM, Sloet van Oldruitenborgh-Oosterbaan MM.Measuring the height of ponies at the withers is currently a prerequisite at Fédération Equestre Internationale (FEI) competitions. A pony measured at a competition site must not measure more than 151 cm with, or 150 cm without horse shoes. When a pony exceeds the regulated height, it is excluded from participation in the competition. Moreover, the sale value of a pony can decrease dramatically if by height measurement it is designated as a 'horse'. The aim of this study was firstly to determine whether measuring ponies at the withers with a laser device is repeatable; secondly, to evaluate ...
Tinkler SH, Couëtil LL, Kennedy SA, Constable PD.To determine whether plasma total CO(2) concentrations would vary with the size of the evacuated tube used to collect blood samples. Methods: Randomized crossover study. Methods: Convenience sample of 20 healthy adult horses. Methods: Jugular venous blood was collected from horses in random order into 8 types of evacuated tubes: 2-mL glass, 2- or 3-mL plastic or plastic plasma separator, 4- or 6-mL plastic, and 10-mL glass or plastic. Total CO(2) concentrations in plasma were measured with a biochemistry analyzer. Data were analyzed via repeated-measures ANOVA and multivariate regression. Resu...
Canola PA, Cardenas JJ, Sá GC, de Paula VB.To evaluate the feasibility of performing needle arthroscopy of the scapulohumeral joint and bicipital bursa in standing horses by using the thoracic limbs of euthanized horses. To that purpose, this experimental study was designed. Ten thoracic limbs, five left and five right from euthanized horses were retained in an upright position to simulate a standing horse. The craniolateral and lateral scapulohumeral arthroscopic portals were used to access the articular structures. A third (caudal) portal was also identified and described. The degree of difficulty in accessing the articular space and...
Giusto G, Gandini M.In equine abdominal surgery, resection and anastomosis of strangulated intestine is a commonly performed procedure. To date, ligatures, vessel sealing devices and the ligate-divide stapler have been described for this use in horses. The objective of this study was to compare the application of haemostatic clips and ligatures to occlude equine mesenteric vessels. Portions of jejunum with ten associated mesenteric vessels were collected from 12 horses at a local abattoir and divided into two groups. Portions of intestine were divided into two sections comprising five vessels each and assigned to...
Ogden NKE, Cullen MD, Stack JD.Accuracy of intrasynovial injections can be challenging to assess in a clinical setting in horses. Contrast-enhanced ultrasonography (CEUS) using injectate agitated with air has been used to determine the success rates of synovial injections in human rheumatology. Objective: To assess the diagnostic sensitivity and specificity of CEUS and to describe its clinical use. Methods: Cadaveric study followed by a prospective descriptive observational study. Methods: Part 1: CEUS was performed following injection of agitated methylene-blue solution targeting 13 different anatomical synovial structures...
Baggot JD, Prescott JF.The success of antimicrobial therapy depends on administration of an agent to which the pathogenic microorganisms are susceptible at the concentrations attained at the site of infection. The route of administration, size of the dose and dosing interval must be appropriate for the drug preparation selected. With penicillins in particular, dosage can be tailored to the severity of the infection and quantitative susceptibility of the microorganism. This approach cannot be applied to aminoglycosides because their relatively narrow margin of safety limits the amount which can be administered. In se...
Spagnolo JD, Castro LM, Corrêa RR, Garcia Filho SG, Ambrósio AM, Baccarin RYA, Hagen SCF, de Sá LM, Silva LCLC.This study aimed to describe and evaluate a laparoscopic technique to promote nephrosplenic space ablation in horses using a homologous pericardium implant, preserved in 98% glycerin and fixed using laparoscopic polydioxanone staples. In this experimental study, six Arabian horses without previous related abdominal diseases were used. The surgical procedures were performed in the standing position under sedation with alpha-2 agonists and opioids, associated with local infiltration of the local anesthetic in the portal sites. The horses were restrained in a stock, and the left flanks were clipp...
Goodrich LR, Moll HD, Crisman MV, Lessard P, Bigbie RB.To evaluate healing of pinch-grafted wounds on the distal aspect of the limbs of ponies bandaged with equine amnion or a standard nonadherent wound dressing material. Methods: 6 ponies. Methods: A 2.5x2.5-cm full-thickness section of skin was removed from the dorsal aspect of each limb at the midpoint of the metacarpus or metatarsus. Six days later, wounds were grafted with partial-thickness pinch grafts. Half the wounds were bandaged with amnion, and the other half were bandaged with a nonadherent dressing. Bandages were changed every 3 days until wound healing was complete. At each bandage c...
Leonardi L, Bertoletti A, Bellezza E, Pettinari I, Gialletti R.Teratoma is a rare germ cell testicular cancer composed of cells that are not normally present in the site where it originates. These tumors are rarely described in horses, where they may develop due to cryptorchidism. Teratomas consist of cells originating from different germinal layers, arising from germinal multi-potential cells with differentiation defects, and can simultaneously contain several tissues from two or more embryonic layers. Testicular teratomas are described in horses, cats, dogs, wild boars, bulls, and humans. In the rare descriptions found in literature of testicular terato...
Dixon PM, Andrew R, Brannon H, Burgess R, Gibson A, Little JC, Orange B, Ross L, Rudolph T, Shaw DJ.A survey of 854 horse owners, trainers and equestrian managers in 10 regions of Great Britain and Ireland showed that 83 per cent provided their horses with routine prophylactic dental care at fixed intervals, including 49 per cent at intervals of 12 months and 30 per cent at intervals of six months; a further 10 per cent provided it only when they felt it was required and 7 per cent did not provide it at all. Overall, 44 per cent of the owners had their horse's wolf teeth (first premolar) extracted routinely; when prophylactic dentistry was provided, it was carried out solely by equine dental...
Castro FA, Schumacher JS, Pauwels F, Blackford JT.To evaluate the accuracy of a new technique for perineural injection of the lateral palmar nerve and to determine frequency of inadvertent injection into the carpal synovial sheath with this technique. Methods: Prospective experimental study. Methods: Thirty equine cadaver forelimbs. Methods: Each of 3 clinicians injected 0.5 mL of a 1% aqueous solution of new methylene blue as a marker at the medial aspect of the accessory carpal bone of 10 limbs. Immediately after each injection, the lateral palmar nerve was identified by dissection of and inspected for proximity of dye, and the carpal synov...
Fouché N, Oesch S, Gerber V, Richter H, Howard J, Peters LM.Sorbitol dehydrogenase (SDH) activity is one of the most sensitive and specific markers for hepatocellular injury in horses, but its reported lability makes it impractical for use in many clinical settings. To date, stability of SDH in equine samples has only been evaluated in a limited number of studies in serum samples of horses with activities within reference intervals. The objective of the study was to determine pre-analytical stability of equine SDH activity in heparinized plasma stored at different temperatures for up to 72 h. Twenty client-owned horses admitted to a veterinary teaching...
Mycotoxin contaminated feed has been associated with colic of horses caused by intestinal disorders. Whether such disease conditions alter the intestinal toxin metabolism and transfer across a compromised mucosal barrier is unknown. A screening approach was used to relate blood residue levels of DON, ZEN and their metabolites to the status of the horses (sick vs. healthy). A total of 55 clinically healthy horses from 6 different farms with varying feeding background served as control for sick horses (N = 102) hospitalized due to colic. ZEN, alpha-zearalenol (ZEL), beta-ZEL and DON were detecta...
Chanda M, Puangthong C, Pathomsakulwong W, Apichaimongkonkun T, Leklub J.Two horses diagnosed with underrun heels leading to navicular syndrome were fitted with Z-bar shoes. They occasionally showed moderate lameness on the affected legs after the sixth and tenth consecutive farrier adjustments. The affected hooves were sensitive to compression of the frog and sole in their palmar regions. Modified Z-bar shoes were created and shod on the lame legs based on previous with regional anaesthesia and recent clinical examination. The lameness scores were slightly improved at the first shoeing with the modified Z-bar shoes but were markedly improved at four and eight week...
Traub-Dargatz JL, Trotter GW, Kaser-Hotz B, Bennett DG, Kiper ML, Veeramachaneni DN, Squires E.Clinical signs of chronic epididymitis in a stallion included recurrent signs of inguinal pain--retraction of the right testis into the inguinal area, resentment of palpation of the right testis, and right-sided scrotal swelling. The tail of the right epididymis was firm and seemed to be adhered to the testis. The tail of the left epididymis felt firmer than normal. Ultrasonographically, the diameter of the head of the epididymis was considered larger than normal, was hyperechoic in relation to the right testis, and had an irregular border. Several bright 1- to 5-mm-diameter echogenic areas th...
Schenck PA, Chew DJ, Brooks CL.It has been previously shown that Ca(I) concentration is stable in serum collected from healthy horses for 10 days if stored at 40 degrees C. This may not be true for horses with abnormal Ca(I) concentrations. Thus the stability of ionized calcium (Ca(I)) concentration and pH measurement in serum from horses with both normal and abnormal Ca(I) concentrations stored for various times at 40 degrees C and -10 degrees C was evaluated. Our results indicated that serum Ca(I) concentration was stable throughout 7 days of cold or frozen storage, after being received by the Clinical Chemistry Laborator...
Galuppo LD, Snyder JR, Pascoe JR, Stover SM, Morgan R.To provide an accurate and detailed description of the laparoscopic anatomy of the abdomen of horses positioned in dorsal recumbency and to compare those observations with laparoscopic anatomy of standing horses. The effects of laparoscopy and positional changes on arterial blood pressure and blood gas values also were investigated. Methods: Descriptive anatomic study. Methods: Laparoscopy was performed on 6 horses (2 mares, 2 geldings, and 2 stallions) to record the normal laparoscopic anatomy of the abdomen in dorsal recumbency. Methods: Feed was withheld from all horses for 36 hours. Horses...
Coleman MC, Slovis NM, Hunt RJ.It has been suggested that the success of gastric bypass surgery in foals for the treatment of gastric outflow obstruction is poor. However, few reports exist evaluating the long-term prognosis of these cases. Objective: To determine the long-term success of foals, including racing records, surgically treated for gastric outflow obstruction secondary to gastroduodenal ulceration. Methods: Medical records of foals undergoing surgical treatment of gastric outflow obstruction secondary to gastroduodenal ulceration were evaluated for clinical information. Owners, trainers and race records were eva...
Venugopal CS, Holmes EP, Polikepahad S, Laborde S, Kearney M, Moore RM.The purpose of the study was to compare in vitro airway responses to neurokinin A & B (NKA and NKB) and expression of NK-2 receptors in airways of horses affected and unaffected with recurrent airway obstruction (RAO). Neurokinin-A, an inflammatory mediator belonging to the tachykinin family of neuropeptides, causes bronchoconstriction by binding to NK-2 receptors. Neurokinin-B is a lesser-known neuropeptide that acts on NK-3 receptors. Horses were placed into RAO-affected and RAO-unaffected groups based on their history, clinical scoring, and pulmonary function testing. Lung tissue from e...
Kuemmerle JM, Uhlig H, Kofler J.Hyaluronate (HA) was administered by intra-articular injection to a 13-year-old Haflinger mare for treatment of metacarpophalangeal osteoarthritis. Ten hours after the injection, a severe inflammatory reaction developed in the treated joint. While awaiting results of synovial fluid analysis, treatment for iatrogenic infectious arthritis was initiated, but the analysis did not confirm sepsis. Clinical signs improved significantly following systemic non-steroidal anti-inflammatory medication and the horse was discharged three days later. Following an intravenous hyaluronate injection, four days ...
Lizarraga I, Castillo F, Valderrama ME.Isoxsuprine is used clinically to treat navicular disease and laminitis in horses. Although it is thought to increase digital and laminar blood flow, isoxsuprine's mechanism of action remains controversial, and analgesia has been suggested recently as such possible mechanism. This research investigated the analgesic potential of isoxsuprine in healthy horses submitted to a mechanical nociceptive test. Isoxsuprine (1.2 mg/kg), xylazine (1.1 mg/kg), distilled water : ethanol 95% (2 : 1, v/v, 20 ml) and saline (0.9%, 20 ml) were injected intravenously, and nociceptive thresholds were measured ove...
Megid Gomaa NA, Köller G, Fritz Schusser G.To measure serum alcohol dehydrogenase (ADH) activity in horses with acute intestinal obstruction and to determine the diagnostic and prognostic utility of this analyte. Methods: Prospective observational study. Methods: University Veterinary Hospital. Methods: Thirty healthy horses (control group) and 77 horses with acute intestinal obstruction, including 36 horses with nonstrangulating obstruction (23 with left ventral colon impaction and 13 with left dorsal displacement [G1], 22 with small intestinal strangulation [G2], and 19 with colon torsion [G3]). Methods: Serum ADH activity was assaye...
