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Topic:Veterinary Practice

Veterinary practice in relation to horses encompasses the medical care, management, and treatment of equine species. This field involves various aspects of equine health, including preventive care, diagnosis, and treatment of diseases, surgical interventions, and emergency care. Equine veterinarians employ a range of diagnostic tools and techniques such as physical examinations, imaging, and laboratory tests to assess and monitor horse health. In addition to addressing physical ailments, veterinary practice also includes nutritional management, reproductive health, and performance-related issues. This page compiles peer-reviewed research studies and scholarly articles that explore the methodologies, advancements, and outcomes in veterinary practices specific to equine health.
Effect of long-term administration of an injectable enrofloxacin solution on physical and musculoskeletal variables in adult horses.
Journal of the American Veterinary Medical Association    January 11, 2000   Volume 217, Issue 10 1514-1521 doi: 10.2460/javma.2000.217.1514
Bertone AL, Tremaine WH, Macoris DG, Simmons EJ, Ewert KM, Herr LG, Weisbrode SE.To evaluate clinical safety of administration of injectable enrofloxacin. Methods: Randomized controlled clinical trial. Methods: 24 adult horses. Methods: Healthy horses were randomly allocated into 4 equal groups that received placebo injections (control) or IV administration of enrofloxacin (5 mg/kg [2.3 mg/lb], 15 mg/kg [6.8 mg/lb], or 25 mg/kg [11.4 mg/lb] of body weight, q 24 h) for 21 days. Joint angles, cross-sectional area of superficial and deep digital flexor and calcaneal tendons, carpal or tarsal osteophytes or lucency, and midcarpal and tarsocrural articular cartilage lesions wer...
Proceedings of the 1st International Congress on Equine Clinical Behaviour. Basel, Switzerland, June 1996.
Equine veterinary journal. Supplement    December 28, 1999   Issue 27 1-64 
No abstract available
Opinion on use of prerace inspection.
Journal of the American Veterinary Medical Association    December 28, 1999   Volume 215, Issue 8 1092-1093 
Gall C.No abstract available
Review of equine laparoscopy and an analysis of 158 laparoscopies in the horse.
Equine veterinary journal    December 22, 1999   Volume 31, Issue 6 456-464 
Walmsley JP.No abstract available
An apparently gluten-induced photosensitivity in horses.
Veterinary and human toxicology    December 11, 1999   Volume 41, Issue 6 386-388 
Yeruham I, Avidar Y, Perl S.Primary photosensitization was observed in 3 Appaloosa mares. The skin lesions were diffuse erythema followed by edema and subsequently weeping and finally dry gangrene and ulceration. The severe photosensitivity dermatitis was apparently induced by gluten ingestion. Resolution of lesions occurred after withdrawal of the suspected dairy concentrate feed and prevention of exposure to sunlight. Neither the ponies nor donkey, which were not fed with the suspected concentrate, exhibited similar skin lesions or other clinical abnormalities. Gluten metabolites may contain photodynamic agents that ca...
Clinical pharmacology of nervous system diseases.
The Veterinary clinics of North America. Equine practice    December 10, 1999   Volume 15, Issue 3 575-588 doi: 10.1016/s0749-0739(17)30133-5
Dowling PM.The well-developed defense barriers of the CNS and the expense of drug therapy limit the pharmacologic options for the treatment of neurologic diseases in horses. New approaches to controlling inflammation in the CNS are improving the outcomes of bacterial meningitis. The appropriate treatment of EPM remains controversial. More research is needed to evaluate the pharmacokinetics and pharmacodynamics of drugs in the CNS of the horse. Behavioral pharmacology has become fashionable in human and small animal medicine, but it needs to be evaluated for the potential of unethical use in performance h...
Pharmacologic considerations in the treatment of neonatal septicemia and its complications.
The Veterinary clinics of North America. Equine practice    December 10, 1999   Volume 15, Issue 3 725-746 doi: 10.1016/s0749-0739(17)30141-4
Wichtel ME, Buys E, DeLuca J, Stringel G.This article focuses on the pharmacologic properties of drugs commonly used in the treatment of neonatal septicemia and its complications. Rational therapy demands an awareness of not only the pharmacology of individual drugs but also the interactions and anticipated fate of such drugs in the rapidly changing physiologic environment of the neonate. Further research in the area of equine neonatal pharmacology should greatly assist our understanding of the impact of the disease state on the unique physiology of the newborn and should allow us to better predict the ultimate fate of drugs commonly...
Equine reproductive pharmacology.
The Veterinary clinics of North America. Equine practice    December 10, 1999   Volume 15, Issue 3 687-x doi: 10.1016/s0749-0739(17)30139-6
Perkins NR.This article reviews therapies and strategies commonly used to treat diseases of the mare's genital tract and modulate the reproductive cycle of the mare. Many reproductive treatments are based on historical use and empirical evidence rather than well controlled clinical studies. This article attempts to present practical information in a summary form while highlighting the need for continued research documenting the efficacy and safety of reproductive therapies.
Treatment and control of gastrointestinal parasites.
The Veterinary clinics of North America. Equine practice    December 10, 1999   Volume 15, Issue 3 561-viii doi: 10.1016/s0749-0739(17)30132-3
Hutchens DE, Paul AJ, DiPietro JA.Routine anthelmintic treatments are one of the most important components of an equine wellness program used by horse owners and veterinarians today. Thirteen different compounds are available in the United States in the treatment of gastrointestinal parasites, most of which are available over the counter. As a result, there is a decreased reliance on the veterinarian to perform routine tube dewormings. Therefore, the future of the veterinarian's role in the management of gastrointestinal parasites is likely to be in the consultation and design of parasite control programs. With this in mind, t...
Formulary of common equine drugs.
The Veterinary clinics of North America. Equine practice    December 10, 1999   Volume 15, Issue 3 747-xi doi: 10.1016/s0749-0739(17)30142-6
Whittem T.This article presents in easily accessible form a collection of drug names and dose rates for the drugs recommended or referred to by the authors of the individual articles in this issue. Although the formulary provides recommendations for drug use, the reader is cautioned that the responsibility for the choice of agent, formulation, dose, and dose interval lies with the clinician. The author also addresses regulations that govern the use of drugs in competition horses.
Equine cardiac disease. Clinical pharmacology and therapeutics.
The Veterinary clinics of North America. Equine practice    December 10, 1999   Volume 15, Issue 3 523-vii doi: 10.1016/s0749-0739(17)30130-x
Mogg TD.Cardiac disease is often life-threatening and challenging to treat. Prolonged therapy is indicated in many cases, which can lead to problems with treatment costs, owner compliance, and potential drug toxicity. Many therapies are empirical or based on data from other species because of a lack of well-designed prospective clinical trials in horses. This article reviews the clinical pharmacology and therapeutics of heart failure, cardiac arrhythmias, myocardial disease, endocarditis, and pericardial disease.
Therapeutics of musculoskeletal disease in the horse.
The Veterinary clinics of North America. Equine practice    December 10, 1999   Volume 15, Issue 3 589-602 doi: 10.1016/s0749-0739(17)30134-7
Kollias-Baker C.Therapeutic medications play a crucial role in the successful therapy of many musculoskeletal diseases that occur in horses. For example, appropriate antibiotic therapy is extremely important in the treatment of diseases caused by infections with microorganisms such as botulism, tetanus, osteomyelitis, and muscle abscesses. In addition, numerous prescription medications and nutritional supplements are available for the treatment of osteoarthritis in horses. Many of these agents currently on the market fall into a new class of drugs called SADMO agents. Unfortunately, the efficacy and mechanism...
Analgesia.
The Veterinary clinics of North America. Equine practice    December 10, 1999   Volume 15, Issue 3 705-723 doi: 10.1016/s0749-0739(17)30140-2
Clark JO, Clark TP.Critical to reducing patient morbidity as well as heightened ethical awareness, alleviation of pain in animals has become integral to medical case management and surgical procedures. Pharmacotherapy is directed at peripheral nociceptors, primary and secondary spinal neurons, and pain-processing areas in the CNS. Accordingly, three primary pharmacologic strategies have evolved: drugs that bind to and activate opioid receptors, drugs that bind to and activate alpha 2 receptors, and drugs that reduce de novo prostaglandin synthesis. In horses, the two predominant types of pain encountered are mus...
Renal pharmacology.
The Veterinary clinics of North America. Equine practice    December 10, 1999   Volume 15, Issue 3 647-ix doi: 10.1016/s0749-0739(17)30137-2
Jose-Cunilleras E, Hinchcliff KW.Pharmacologic treatment of diseases of the urinary tract of horses is limited to administration of antibiotics for treatment of urinary tract infections (UTIs), administration of drugs that alter urine pH, administration of drugs that alter bladder smooth muscle function or urethral sphincter tone, and treatment of acute renal failure. The indications, mechanisms of action, pharmacokinetic characteristics, and adverse effects of these agents in each of these groups are discussed in this article. The use of the agents is discussed within the context of the pathophysiology of the disease being t...
Modes of local drug delivery to the musculoskeletal system.
The Veterinary clinics of North America. Equine practice    December 10, 1999   Volume 15, Issue 3 603-622 doi: 10.1016/s0749-0739(17)30135-9
Anderson BH, Ethell MT.A number of methods for the local delivery of drugs to musculoskeletal tissues in the horse are now available. Further research is required to document the disposition of drugs delivered by such methods and to correlate this information with efficacy. Perhaps the greatest potential area for the methods discussed is the treatment of synovial and bone infections. To be able to provide high and sustained therapeutic concentrations of antimicrobials to the site of infection should increase the chances of success in such cases. These methods of drug delivery need to be used in conjunction with othe...
Equine infectious keratitis.
The Veterinary clinics of North America. Equine practice    December 10, 1999   Volume 15, Issue 3 623-646 doi: 10.1016/s0749-0739(17)30136-0
Hamor RE, Whelan NC.Corneal ulcers are one of the most common ocular disease presentations in the horse. With the use of correct diagnostic techniques and selection of an appropriate treatment regimen, most cases result in a satisfactory outcome. The eye does not respond well to inflammation, and in complicated ulcers, this should be managed aggressively using systemic NSAIDs with a high priority assigned to removing the infectious agent. Care needs to be taken to avoid topical or systemic corticosteroid use for the treatment of equine ocular disease, however, unless the clinician is completely sure that the corn...
Inhaled carbon monoxide concentration during halothane or isoflurane anesthesia in horses.
Veterinary surgery : VS    December 3, 1999   Volume 28, Issue 6 506-512 doi: 10.1111/j.1532-950x.1999.00506.x
Dodam JR, Branson KR, Gross ME, Petroski GF.The purpose of this study was to assess carbon monoxide (CO) exposure during equine anesthesia with either halothane (H) or isoflurane (I) delivered in a circle rebreathing system. Methods: Prospective clinical investigation. Methods: Fifty client-owned horses. Methods: Horses were randomly assigned for anesthetic maintenance with H (n = 26) or I (n = 24). Two large animal anesthetic machines were used and assigned to a single agent for 2-4 weeks at a time. Machines were disassembled and soda lime changed prior to switching anesthetic agents. Inhalant anesthetic concentration and CO concentrat...
Monthly, daily, and circadian variations of measurements of pulmonary mechanics in horses with chronic obstructive pulmonary disease.
American journal of veterinary research    November 24, 1999   Volume 60, Issue 11 1341-1346 
Jean D, Vrins A, Lavoie JP.To determine temporal variations of pulmonary function in horses without respiratory tract disease (controls) and horses with chronic obstructive pulmonary disease (COPD) and determine whether reversibility of airway obstruction after environmental control can be predicted by response to atropine administration. Methods: 7 COPD-affected and 5 control horses. Methods: Pulmonary function testing was performed monthly during 3 consecutive months, daily for 5 consecutive days, and at 6-hour intervals for 24 hours before and after administration of atropine (0.02 mg/kg of body weight, i.v.) and aft...
Use of unlicensed medicines.
The Veterinary record    October 26, 1999   Volume 145, Issue 12 352 
Keith NW.No abstract available
Supporting forelimb lameness: clinical judgement vs. computerised symmetry measurement.
Equine veterinary journal    October 3, 1999   Volume 31, Issue 5 417-421 doi: 10.1111/j.2042-3306.1999.tb03842.x
Peham C, Licka T, Girtler D, Scheidl M.The aim of this study was to compare supporting forelimb lameness determined by a motion analysis system with the subjective grading of a trained equine orthopaedic surgeon. Trotting on a treadmill, 29 individuals with a supporting forelimb lameness were measured with the SELSPOT II system and judged by the clinician. The vertical motion of the head was measured, analysed using Fourier transform, and the percentages of symmetry determined. The veterinarian evaluated the lameness and graded it according to a clinical routine. Veterinarian and system for motion analysis assigned the lameness to ...
Pharmacokinetics of ibuprofen after intravenous and oral administration and assessment of safety of administration to healthy foals.
American journal of veterinary research    September 18, 1999   Volume 60, Issue 9 1066-1073 
Breuhaus BA, DeGraves FJ, Honore EK, Papich MG.To determine pharmacokinetics of ibuprofen in healthy foals and to determine clinical effects after oral administration for 6 days. Methods: 7 healthy 5- to 10-week-old foals. Methods: Serum concentrations of ibuprofen were measured after IV and oral (nasogastric tube) administration at dosages of 10 and 25 mg/kg of body weight. Foals were given ibuprofen (25 mg/kg, PO, q 8 h) as a paste for 6 days. Serum and urine were obtained before and after the 6-day period. Results: Half-life of elimination (Kel t1/2) of IV-administered ibuprofen (ie, 10 and 25 mg/kg), was 79 and 108 minutes, maximal ser...
Validity of saddle pressure measurements using force-sensing array technology–preliminary studies.
Veterinary journal (London, England : 1997)    September 18, 1999   Volume 158, Issue 2 113-119 doi: 10.1053/tvjl.1998.0334
Jeffcott LB, Holmes MA, Townsend HG.Back pain is a common and poorly understood clinical problem. An important factor in this regard is the induction or exacerbation of back pain from badly designed or poorly fitting saddles. This study used a pressure-sensing mat to investigate saddle fit. The aims of the study were to confirm the accuracy and reliability of the force-sensing array technology when used to measure pressure beneath the saddles of horses, and to collect some initial data from normal healthy horses with well-fitting saddles. Experiments were undertaken to establish that a linear relationship existed between the tot...
Equine clinical behaviour.
Equine veterinary journal. Supplement    September 15, 1999   Issue 27 3 doi: 10.1111/j.2042-3306.1998.tb05134.x
Bracher V, Stohler T.No abstract available
Characterisation of headshaking syndrome–31 cases.
Equine veterinary journal. Supplement    September 15, 1999   Issue 27 28-29 doi: 10.1111/j.2042-3306.1998.tb05141.x
Madigan JE, Bell SA.Headshaking is a maturity onset condition with the most commonly reported clinical signs being 'flipping' of the nose, nose rubbing, snorting or sneezing, and acting like a bee is flying up the nostril. A questionnaire was completed by owners of 31 horses with headshaking syndrome. The history, time of onset, clinical presentation and treatment of this condition were reported. Headshaking appeared to be light-stimulated in approximately 60% of the horses. The condition is seasonal and recurring in the majority of horses. Treatment with cyproheptadine produced improvement of symptoms in 76% of ...
The identification of abnormal behaviour and behavioural problems in stabled horses and their relationship to horse welfare: a comparative review.
Equine veterinary journal. Supplement    September 15, 1999   Issue 27 5-9 doi: 10.1111/j.2042-3306.1998.tb05136.x
Cooper JJ, Mason GJ.Many behaviours in domestic animals, such as the 'stable vices' of horses, are treated because they are considered undesirable for economic or cultural reasons, and not because the activity affects the horse's quality of life. The impact of a behaviour on the human reporter is not a function of its impact on the animal performer, and an understanding of the causes and effects of the particular activity is necessary to assess the costs and benefits of treatment. Where the behaviour is a sign of poor welfare, such as an inadequate environment, treatment can best be achieved by removing these und...
The pharmacologic basis for the treatment of developmental and acute laminitis.
The Veterinary clinics of North America. Equine practice    September 3, 1999   Volume 15, Issue 2 345-362 doi: 10.1016/s0749-0739(17)30149-9
Brumbaugh GW, Sumano López H, Hoyas Sepúlveda ML.Each horse with laminitis is presented to the veterinarian at a different stage in progression of the condition and with varying severity. The pathogenic timing is often unknown and is difficult to determine. Because timing and severity are related to both the lesion's severity and responsiveness to treatment, these factors are critical to treatment selection and success. It is erroneous to assume that each horse with laminitis should receive each treatment. It is therefore important to ascertain as logically and objectively as possible the pathophysiological stage of development of each horse...
Clinical presentation, diagnosis, and prognosis of acute laminitis.
The Veterinary clinics of North America. Equine practice    September 3, 1999   Volume 15, Issue 2 311-vi doi: 10.1016/s0749-0739(17)30147-5
Swanson TD.The purpose of this article is to describe the clinical features present in the patient affected with acute laminitis. The variations in the stance and characteristic lameness of the acute disease are described in relation to the disease severity and limb involvement. The elements of establishing a diagnosis including clinical history, physical and radiologic evaluation, and differential diagnosis are discussed. Difficulties and criteria used in establishing a prognosis of the acute phase patient are defined.
Trimming and shoeing the chronically affected horse.
The Veterinary clinics of North America. Equine practice    September 3, 1999   Volume 15, Issue 2 463-480 doi: 10.1016/s0749-0739(17)30155-4
Curtis S, Ferguson DW, Luikart R, Ovnicek G.Several of the technical approaches applied to the foot overlap with regard to intent. Frog or solar support, for example, may be provided either to stabilize the distal phalanx within the hoof capsule or in an effort to unload regional pain arising from the solar surface of the foot. It is likewise obvious that some techniques such as lowering the heels to achieve phalangeal realignment and raising the heels to relieve deep digital flexor tendon tension are contradictory. In these instances, it is not that one technique is always correct but that differences exist among horses. Currently, it ...
Treatment of acute laminitis. Supportive therapy.
The Veterinary clinics of North America. Equine practice    September 3, 1999   Volume 15, Issue 2 363-374 doi: 10.1016/s0749-0739(17)30150-5
Parks AH, Balch OK, Collier MA.Over the last decade, both the farriery and veterinary professions have greatly increased their collective experience and understanding of the treatment of acute laminitis. Many horses that would have not been considered candidates for treatment 10 to 15 years ago are now saved, and some progress to successful careers as athletes. Unfortunately, the difficulties over prediction of the course of the disease persist, which continues to complicate treatment decisions. By its nature, supportive therapy is designed to make the horse more comfortable and limit further laminar injury by countering ad...
Clinicopathological features of equine primary hepatic disease: a review of 50 cases.
The Veterinary record    August 31, 1999   Volume 145, Issue 5 134-139 doi: 10.1136/vr.145.5.134
McGorum BC, Murphy D, Love S, Milne EM.The clinicopathological features of 50 cases of equine hepatic disease were reviewed. There was a wide range of clinical signs and at least 50 per cent of the animals exhibited either dull demeanour, anorexia, abdominal pain, cerebral dysfunction and/or weight loss. Life-threatening complications of hepatic failure recorded were: gastric impaction in 10 cases, bilateral laryngeal paralysis in seven cases and coagulopathy in five cases. All the cases had high activities of gamma-glutamyl transferase (GGT) and most had high activities of glutamate dehydrogenase (GLDH) and high concentrations of ...
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