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Topic:Veterinary Research
Veterinary research in horses encompasses the study of diseases, health management, and medical treatments specific to equine species. This field investigates various aspects of horse health, including infectious diseases, metabolic disorders, and musculoskeletal conditions. Researchers focus on understanding the pathophysiology of equine ailments, developing diagnostic tools, and evaluating therapeutic interventions. The study of horse health also involves examining preventive measures such as vaccination protocols and nutritional management to promote overall well-being. This page collects peer-reviewed research studies and scholarly articles that explore the diverse areas of veterinary science related to horses, providing insights into disease mechanisms, treatment strategies, and advancements in equine healthcare.
[Effect of 2 methods of demineralization on the on the preservation of glycoproteins and proteoglycans in the intertubular and peritubular dentin in the horse]. The effect of 2 methods of demineralization on the preservation of proteoglycans and glycoproteins was studied in the intertubular and peritubular dentine of the horse. The specimens embedded in Epon were demineralized with a 2% acid formic solution (Bonucci and Gheradi, 1975). Other fragments were treated with an organic solution of EDTA alkylammonium salt (Scott and Kyffin, 1979). These methods preserved in a satisfactory way these labile organic components. In the intertubular dentine, glycoproteins and proteoglycans were also identified, either associated with collagen fibres as a glue and...
Lymphocyte responses to virus and mitogen in ponies during experimental infection with equine herpesvirus 1. Six pony foals, experimentally infected with equine herpesvirus 1 (EHV-1), were studied for their lymphocyte responses to EHV-1 and phytohemagglutinin (PHA) stimulations. Lymphocyte blastic transformation in the presence of EHV-1 appeared as early as 2 days after the foals were inoculated, reached a peak in 7 to 10 days, and subsequently decreased. In contrast, the lymphocyte blastic transformation in the presence of PHA increased sharply, reaching a peak in 2 to 3 days, and then decreased to its lowest level in 10 days after which it returned to its near preinoculation level. As for the mecha...
Helix packing and subunit conformation in horse spleen apoferritin. An electron density map of horse spleen apoferritin at 0.28-nm (2.8 A) resolution and its preliminary interpretation have been described previously. Rigorous examination of this and newer maps at the same nominal resolution but calculated from more extensive data sets, including model building in a Richards' comparator, now allows us to report on structural features in more detail. We list inter-helical angles within and between neighbouring subunits, and describe a new short region of inter-subunit anti-parallel pleated sheet. A short section of electron density not properly accounted for in ...
Rectal prolapse in the horse. Eleven horses with rectal prolapses were examined at Purdue University. Nine of the 11 prolapses were corrected by submucosal resection. Four of those were treated by a modified submucosal resection that apposes mucosa as well as submucosa. Follow-up of 8 cases, at intervals ranging from 4 months to 6 years, established that rectal prolapse did not recur following the resection.
Effects of denervation of the digit of the horse. A study was conducted in an effort to explain why digital necrosis sometimes follows neurectomy in the horse. Six horses were subjected to unilateral section of the medial and lateral palmar nerves. Arteriography was done on each digit prior to surgery. Terminally, arteriography was repeated. Sections of bone, nerve, artery, skin, coronary band, and deep flexor tendon were examined histologically. Changes in arterial pattern and bone quality were noted. During the study, 2 of the horses had clinical signs of digital necrosis. The composite findings suggested trauma or infection, or both, of th...
[The immunological relation between human and equine Gc proteins (author’s transl)]. The immunological comparison of human and equine Gc proteins showed partial identical reactions between both species. Immunizations of goats and rabbits with horse serum produced antisera able to recognize human Gc proteins.
Counselling for genetic diseases of horses. Dead or deformed foals produced by purebred parents represent an economic and emotional loss to the horse breeder. In order to avoid producing such defective foals in the future, the breeder may seek guidance in determining whether their origin is environmental or genetic. Only a few genetic diseases of horses have been rigorously defined. Selected, rare genetic diseases that prevent reproduction, cause the natural death, or necessitate the humane destruction of a foal before it fulfills its intended purpose serve as examples for collecting evidence to define the genetics of other deleterious ...
The major metabolite of fentanyl in the horse. Fentanyl, a potent, synthetic narcotic analgesic, has reportedly been used to "dope" racehorses. Urine was collected from a horse dosed with 70 mg of [3H]fentanyl, and the primary metabolite, a water-soluble, amphoteric compound, was isolated by high-pressure liquid chromatography and identified by spectroscopic analysis. This metabolite was found to be N-[1-(2-phenethyl-4-piperidinyl)] malonanilinic acid.
Aspects of genetics and disease in the horse. Dead or deformed foals produced by purebred parents represent an economic and emotional loss to the horse breeder. To avoid repeating production of such defective foals, the breeder may seek assistance in identifying the possible environmental or genetic causes for such animals. Only a few genetic diseases of the horse have been rigorously defined. Selected rare genetic diseases that prevent reproduction, cause the natural death or necessitate the humane destruction of a foal before it fulfills its intended purpose serve as examples for the definition of genetics of other deleterious diseases ...
Quantitative epidemiological studies on the prevalence of babesiosis in horses in Kuwait. Racehorses imported into Kuwait were tested for serum antibodies to Babesia equi and B. caballi by complement fixation (CF) and indirect fluorescent antibody (IFA) tests. The prevalence of B. equi was high (77.1% by IFA) whereas that of B. caballi was much lower (11.4%). Data for B. equi showed that infection was acquired after about 6 months at risk and that in the following 12 months animals had antibody levels detectable by both CF and IFA tests by 24 months the CF reaction was no longer detectable. Estimates of incidence and inoculation rates were calculated and found to be consistent with...
Efficacy of ivermectin (22,23-dihydroavermectin B1) against gastrointestinal parasites in ponies. The controlled test method was used to evaluate the antiparasitic efficacy of IM inoculated 22,23-dihydroavermectin B1 (ivermectin) against gastrointestinal parasites of horses (ponies). Parasite infections were naturally acquired in southern Louisiana. Dose levels of the drug tested were 0.2 mg/kg, 0.3 mg/kg, and 0.5 mg/kg. Ivermectin at all dose levels tested had an efficacy greater than 97% (P less than 0.05) against Gasterophilus intestinalis larvae, Trichostrongylus axei, Oxyuris equi larvae, Strongylus vulgaris, S edentatus, 15 species of small strongyles, and small strongyle larvae. Pon...
Pancreatic beta-cell function in the fetal foal and mare. Insulin secretion and the factors influencing beta-cell function were investigated in the chronically catheterized fetal foal and mare during the second half of gestation. The response of the fetal beta cells to exogenous glucose was also examined. The mean concentration of insulin in the fetal foal was 7.5 +/- 0.5 (S.E.M.) microunit./ml (n = 20) which was significantly less than the corresponding maternal value of 49.0 +/- 5.0 microunit./ml (n = 20, P < 0.01). The insulin concentration in non-pregnant horses was 24.5 +/- 1.5 microunit./ml (n = 5) which was significantly less than the value...
Attempted induction of an avian eosinophilia using various agents. A series of experiments is described in which attempts were made to produce an avian eosinophilia using various agents. Although none of the experiments was decisive, two demonstrated a slight rise in the eosinophil counts. In one experiment horse serum was injected into a group of fowls on alternate days for 42 days. No eosinophils were seen in any blood smears after this treatment. After a rest period of eight days the birds received further injections for 10 days. The mean eosinophil count rose to over 4 per cent with a range of 1 to 11 per cent. It is considered that this type of response ...
Correlation of dermal-epidermal laminar lesions of equine hoof with various disease conditions. Dermal and epidermal laminar lesions were correlated with acute intestinal, primary hepatic, septicemic, chronic laminar, and acute laminar diseases. Horses with acute intestinal disease had edema in the secondary dermal laminae. Those with hepatic disease had increased keratinization of the secondary epidermal laminae. Septicemia caused increased keratin formation in the primary and secondary epidermal laminae. Chronic laminitis caused architectural changes of the epidermal laminae characterized by hyperplasia and keratin formation of the basal epidermal layer. Horses with acute laminitis had...
Selected ion monitoring assay for bromhexine in biological fluids. A method has been developed for quantification of bromhexine in plasma using gas chromatography mass spectrometry with selected ion monitoring. A deuterium labelled analogue was synthesized and used as the internal standard. To evaluate the gas chromatographic electron capture detection method described earlier, 23 plasma samples have been analysed by both techniques. Although a good correlation was shown, selected ion monitoring was superior to the electron capture detection method for levels below 3 ng ml-1. The mass spectrometric method has also been used to set up a pharmacokinetic study o...
