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Topic:Veterinary Science

Veterinary science and horses encompass the study and application of medical, surgical, and therapeutic practices to maintain and improve the health and welfare of equines. This field addresses a wide range of topics, including disease prevention, diagnosis, and treatment, as well as nutrition, reproduction, and behavior. Research in veterinary science for horses often involves understanding the pathophysiology of equine-specific diseases, developing advanced diagnostic techniques, and improving treatment protocols. This page gathers peer-reviewed research studies and scholarly articles that explore various aspects of veterinary science related to horses, providing insights into the latest advancements and methodologies in equine healthcare.
Recent clinical trials of cancer immunogene therapy in companion animals.
World journal of experimental medicine    May 20, 2017   Volume 7, Issue 2 42-48 doi: 10.5493/wjem.v7.i2.42
This mini-review presents the results of veterinary clinical trials on immunogene therapy published from 2014 to 2016. A variety of tumors, among them melanoma (canine and equine), mastocytoma (canine), mammary adenocarcinoma (canine) and fibrosarcoma (feline) were treated by using diverse strategies. Non-viral vectors were usually employed to transfer genes of cytokines, suicide enzymes and/or tumor associated antigens. In general terms, minor or no adverse collateral effects were related to these procedures, and treated patients frequently improved their conditions (better quality of life, d...
What is your diagnosis? Blood smear from a horse.
Veterinary clinical pathology    May 19, 2017   Volume 46, Issue 3 542-543 doi: 10.1111/vcp.12504
Boes KM, Weinstein NM.No abstract available
Ingestive mastication in horses resembles rumination but not ingestive mastication in cattle and camels.
Journal of experimental zoology. Part A, Ecological and integrative physiology    May 17, 2017   Volume 327, Issue 2-3 98-109 doi: 10.1002/jez.2075
Dittmann MT, Kreuzer M, Runge U, Clauss M.Horses achieve a higher degree of particle size reduction through ingestive mastication than functional ruminants. We characterized mastication using chew-monitoring halters (RumiWatch) in six domestic horses, cattle, and Bactrian camels each. All animals were offered grass hay of the same batch for 15 min. In cattle and camels, measurements were continued after eating until rumination was observed. Except for one horse, 96% of the horses' ingestive mastication data were identified as "rumination" by the proprietary RumiWatch algorithm, whereas ingestion and rumination by cattle and camels wer...
Preliminary investigations into a novel, long-acting, injectable, intramuscular formulation of omeprazole in the horse.
Equine veterinary journal    May 17, 2017   Volume 49, Issue 6 795-801 doi: 10.1111/evj.12688
Sykes BW, Kathawala K, Song Y, Garg S, Page SW, Underwood C, Mills PC.Pilot investigations have suggested that a novel, long-acting, injectable i.m. formulation of omeprazole (LA-OMEP) can induce acid suppression for up to 7 days following a single injection. Objective: To investigate the pharmacodynamics and assess the clinical efficacy of the LA-OMEP formulation. Methods: Part A comprised a pharmacodynamic study. Part B consisted of a pilot clinical trial. Methods: Part A enrolled six adult Thoroughbred horses with percutaneous gastrotomy tubes. Intragastric pH was measured for continuous 23-h periods (08.00-07.00 h) for eight consecutive days (days 0-7). A si...
Are horses capable of mirror self-recognition? A pilot study.
PloS one    May 16, 2017   Volume 12, Issue 5 e0176717 doi: 10.1371/journal.pone.0176717
Baragli P, Demuru E, Scopa C, Palagi E.Mirror Self-Recognition (MSR) unveils complex cognitive, social and emotional skills and it has been found only in humans and few other species, such as great apes, dolphins, elephants and magpies. In this pilot study, we tested if horses show the capacity of MSR. Four subjects living socially under naturalistic conditions were selected for the experiment. We adopted the classical mark test, which consists in placing a coloured mark on an out-of-view body part, visible only through mirror inspection. If the animal considers the image as its own, it will use its reflection to detect the mark an...
High metabolic activity of tissue-nonspecific alkaline phosphatase not only in young but also in adult bone as demonstrated using a new histochemical detection protocol.
General and comparative endocrinology    May 11, 2017   Volume 258 109-118 doi: 10.1016/j.ygcen.2017.05.008
Maly IP, Eppler E, Müller-Gerbl M.Tissue-nonspecific alkaline phosphatase (TNAP) is playing a key role in bone calcification, as has been demonstrated in different mammalian species including human and rodents. However, to investigate age-related changes during life history, histochemical demonstration of TNAP is severely hampered, particularly in the elderly, by technical difficulties associated with sectioning calcified tissue. Sufficient fixation must precede decalcification since poorly fixed bone tissue is exposed to the deleterious effects of decalcification reagents. In order to find a method that would allow cryosectio...
Lack of significant associations with early career performance suggest no link between the DMRT3 “Gait Keeper” mutation and precocity in Coldblooded trotters.
PloS one    May 10, 2017   Volume 12, Issue 5 e0177351 doi: 10.1371/journal.pone.0177351
Jäderkvist Fegraeus K, Lawrence C, Petäjistö K, Johansson MK, Wiklund M, Olsson C, Andersson L, Andersson LS, Røed KH, Ihler CF, Strand E....The Swedish-Norwegian Coldblooded trotter (CBT) is a local breed in Sweden and Norway mainly used for harness racing. Previous studies have shown that a mutation from cytosine (C) to adenine (A) in the doublesex and mab-3 related transcription factor 3 (DMRT3) gene has a major impact on harness racing performance of different breeds. An association of the DMRT3 mutation with early career performance has also been suggested. The aim of the current study was to investigate this proposed association in a randomly selected group of CBTs. 769 CBTs (485 raced, 284 unraced) were genotyped for the DMR...
Galloping Hooves in Africa: Horse, Zebra, or Wildebeest?
Annals of the American Thoracic Society    May 2, 2017   Volume 14, Issue 5 624-625 doi: 10.1513/AnnalsATS.201701-061ED
Rylance S, Mortimer K.No abstract available
Discrimination of Streptococcus equi subsp. equi and Streptococcus equi subsp. zooepidemicus using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Mani RJ, Thachil AJ, Ramachandran A.Accurate and timely identification of infectious etiologies is of great significance in veterinary microbiology, especially for critical diseases such as strangles, a highly contagious disease of horses caused by Streptococcus equi subsp. equi. We evaluated a matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) platform for use in species- and subspecies-level identification of S. equi isolates from horses and compared it with an automated biochemical system. We used 25 clinical isolates each of S. equi subsp. equi and S. equi subsp. zooepidemicus. Using ...
Phenotypic and Genetic Analysis of the Leopard Complex Spotting in Noriker Horses.
The Journal of heredity    April 30, 2017   Volume 108, Issue 5 505-514 doi: 10.1093/jhered/esx039
Druml T, Grilz-Seger G, Neuditschko M, Neuhauser B, Brem G.Genetic analyses of coat colors are frequently restricted to subjectively categorized phenotype information. The aim of this study was to develop a method to numerically quantify the variability of leopard complex (LP) spotting phenotypes introducing tools from image analysis. Generalized Procrustes analysis eliminates systematic errors due to imaging process. The binarization of normalized images and the application of principal component analysis (PCA) on the derived pixel matrices, transform pixel information into numerical data space. We applied these methods on 90 images to ascertain the ...
Laparoscopic evaluation of the small intestine in the standing horse: Technique and effects.
Veterinary surgery : VS    April 29, 2017   Volume 46, Issue 6 812-820 doi: 10.1111/vsu.12664
Jones ARE, Ragle CA, Anderson D, Scott C.To evaluate the feasibility and clinical outcomes after laparoscopic evaluation of the small intestines via laparoscopy. Methods: Prospective pilot study. Methods: Healthy adult horses (n = 5). Methods: Horses were restrained in standing stocks and received an infusion of detomidine. One port was placed in the left last intercostal space and 3 ports were placed in the right paralumbar fossa. The small intestine was run with atraumatic laparoscopic grasping forceps, from the duodenocolic plica to the ileocecal plica. Postoperative pain was scored every 4 hours for the first 48 hours. Horses...
Molecular confirmation of Sarcocystis fayeri in a donkey.
Veterinary parasitology    April 29, 2017   Volume 240 30-33 doi: 10.1016/j.vetpar.2017.04.026
Coultous RM, Raftery AG, Shiels BR, Sutton DGM, Weir W.Sarcocystis fayeri is a canine protozoan parasite with an equine intermediate host. Historically classified as an incidental pathogen, recent literature has described the toxic effects of Sarcocystis fayeri in human food poisoning, and highlighted potential involvement in equine neuromuscular disease. Until now, horses were believed to be the exclusive intermediate host. This study reports the first molecular confirmation of S. fayeri in a donkey, and gives rise to the consideration of donkeys being a potential reservoir for the parasite. This finding is of particular importance in understandi...
Effects of tourniquet number and exsanguination on amikacin concentrations in the radiocarpal and distal interphalangeal joints after low volume intravenous regional limb perfusion in horses.
Veterinary surgery : VS    April 29, 2017   Volume 46, Issue 5 675-682 doi: 10.1111/vsu.12662
Schoonover MJ, Moser DK, Young JM, Payton ME, Holbrook TC.To determine the influence of a dual tourniquet technique and limb exsanguination on amikacin concentrations in the synovial fluid of the radiocarpal joint (RCJ) and distal interphalangeal joint (DIPJ) after low volume, cephalic intravenous regional limb perfusion (IVRLP). Methods: Randomized cross-over design. Methods: Six healthy adult horses. Methods: One gram of amikacin in 6 mL of 0.9% NaCl was infused via cephalic IVRLP in 6 standing, sedated horses using 4 techniques: proximal pneumatic tourniquet (P), proximal pneumatic tourniquet with exsanguination (PE), proximal pneumatic and distal...
Application of Genomic Estimation Methods of Inbreeding and Population Structure in an Arabian Horse Herd.
The Journal of heredity    April 27, 2017   Volume 108, Issue 4 361-368 doi: 10.1093/jhered/esx025
Al Abri MA, König von Borstel U, Strecker V, Brooks SA.Horse breeders rely heavily on pedigrees for identification of ancestry in breeding stock. Inaccurate pedigrees may erroneously assign individuals to false lineages or breed memberships resulting in wrong estimates of inbreeding and coancestry. Moreover, discrepancies in pedigree records can lead breeders seeking to limit inbreeding into making misguided breeding decisions. Genome-wide SNPs provide a quantitative tool to aid in the resolution of lineage assignments and the calculation of genomic measures of relatedness. The aim of this project was to pilot a comparison between pedigree and gen...
Whole genome sequencing reveals a novel deletion variant in the KIT gene in horses with white spotted coat colour phenotypes.
Animal genetics    April 26, 2017   Volume 48, Issue 4 483-485 doi: 10.1111/age.12556
Dürig N, Jude R, Holl H, Brooks SA, Lafayette C, Jagannathan V, Leeb T.White spotting phenotypes in horses can range in severity from the common white markings up to completely white horses. EDNRB, KIT, MITF, PAX3 and TRPM1 represent known candidate genes for such phenotypes in horses. For the present study, we re-investigated a large horse family segregating a variable white spotting phenotype, for which conventional Sanger sequencing of the candidate genes' individual exons had failed to reveal the causative variant. We obtained whole genome sequence data from an affected horse and specifically searched for structural variants in the known candidate genes. This...
Head and pelvic movement asymmetries at trot in riding horses in training and perceived as free from lameness by the owner.
PloS one    April 25, 2017   Volume 12, Issue 4 e0176253 doi: 10.1371/journal.pone.0176253
Rhodin M, Egenvall A, Haubro Andersen P, Pfau T.Recent studies evaluating horses in training and considered free from lameness by their owners have identified a large proportion of horses with motion asymmetries. However the prevalence, type and magnitude of asymmetries when trotting in a straight line or on the lunge have not been investigated. The aim of this study was to objectively investigate the presence of motion asymmetries in riding horses in training by identifying the side and quantifying the degree and type (impact, pushoff) of forelimb and hind limb asymmetries found during straight line trot and on the lunge. In a cross-sectio...
Dourine: a neglected disease of equids.
Tropical animal health and production    April 24, 2017   Volume 49, Issue 5 887-897 doi: 10.1007/s11250-017-1280-1
Gizaw Y, Megersa M, Fayera T.Dourine is a venereal transmitted trypanosomosis causing a major health problem threatening equines worldwide. The origin and identification of Trypanosoma equiperdum within the subgenus Trypanozoon is still a subject of debate. Unlike other trypanosomal infections, dourine is transmitted almost exclusively by coitus. Diagnosis of dourine has continued to be a challenge, due to limited knowledge about the parasite and host-parasite interaction following infection. The pathological lesions caused by the diseases are poorly described and are observed mainly in the reproductive organs, in the ner...
Equine ovarian tissue viability after cryopreservation and in vitro culture.
Theriogenology    April 23, 2017   Volume 97 139-147 doi: 10.1016/j.theriogenology.2017.04.029
Gastal GDA, Aguiar FLN, Alves BG, Alves KA, de Tarso SGS, Ishak GM, Cavinder CA, Feugang JM, Gastal EL.Ovarian tissue cryopreservation allows the preservation of the female fertility potential for an undetermined period. The objectives of this study were to compare the efficiency of cryoprotective agents (CPAs; dimethyl sulfoxide, DMSO; ethylene glycol, EG; and propylene glycol, PROH) using slow-freezing and vitrification methods, and evaluate the viability of cryopreserved equine ovarian tissue after 7 days of culture. Fresh and cryopreserved ovarian fragments were evaluated for preantral follicle morphology, stromal cell density, EGFR, Ki-67, Bax, and Bcl-2 protein expression, and DNA fragmen...
Angiographic anatomy of the extracranial and intracranial portions of the internal carotid arteries in donkeys.
Irish veterinary journal    April 20, 2017   Volume 70 12 doi: 10.1186/s13620-017-0090-0
Khairuddin NH, Sullivan M, Pollock PJ.In horses, the extracranial and intracranial pathway of the internal carotid artery has been described. The extracranial pathway of the internal carotid artery begins at the carotid termination and runs on the dorsal surface of the medial compartment of the guttural pouch. Thereafter the internal carotid artery passes through the foramen lacerum to continue intracranially, forming part of the rostrolateral quadrants of the cerebral arterial circle (Circle of Willis). The objectives of this study were to define and record the anatomy of the carotid arterial tree and the internal carotid artery ...
Leisure riding horses: research topics versus the needs of stakeholders.
Animal science journal = Nihon chikusan Gakkaiho    April 19, 2017   Volume 88, Issue 7 953-958 doi: 10.1111/asj.12800
Janczarek I, Wilk I.Horses intended for leisure riding do not undergo any selection and most often retired sports horses or defective horses are chosen, as a low selling price determines their purchase by a leisure riding center. Unfortunately, horses bought at low prices usually have low utility value, are difficult to handle, require a special or individual approach and do not provide satisfaction in riding. However, neither modern horse breeding nor scientific research address the need to breed horses for leisure activities. There is no clear definition of a model leisure horse and criteria or information for ...
Vet students help regiments declare their horses to be ‘strangles free’.
The Veterinary record    April 15, 2017   Volume 180, Issue 15 373 doi: 10.1136/vr.j1816
No abstract available
Influence of riders’ skill on plasma cortisol levels of horses walking on forest and field trekking courses.
Animal science journal = Nihon chikusan Gakkaiho    April 12, 2017   Volume 88, Issue 10 1629-1635 doi: 10.1111/asj.12801
Ono A, Matsuura A, Yamazaki Y, Sakai W, Watanabe K, Nakanowatari T, Kobayashi H, Irimajiri M, Hodate K.The aim of this study was to evaluate the influence of rider's skill on the plasma cortisol levels of trekking horses on two courses, walking on field and forest courses (about 4.5 to 5.1 km each). Three riders of different skills did horse trekking (HT) in a tandem line under a fixed order: advanced-leading, beginner-second and intermediate-last. A total of six horses were used and they experienced all positions in both courses; a total of 12 experiments were done. Blood samples were obtained before HT, immediately after and 2 h after HT. As a control, additional blood samples were obtained...
Science-in-brief: Equine asthma diagnosis: Beyond bronchoalveolar lavage cytology.
Equine veterinary journal    April 8, 2017   Volume 49, Issue 3 263-265 doi: 10.1111/evj.12679
Bullone M, Lavoie JP.No abstract available
[Doping relevant substances in horse feed].
Schweizer Archiv fur Tierheilkunde    April 7, 2017   Volume 159, Issue 4 231-235 doi: 10.17236/sat00112
Herholz C, Zink N, Laska H, Gumpendobler M, Trolliet C, Probst S.Horse feed material of Swiss and foreign production available on the Swiss market was tested with regard to possible contamination with 7 different alkaloids, atropine and colchicine. Twenty-eight feed samples as well as 2 poppy seed samples were analyzed. Out of 28 feed samples 18 were positive for prohibited substances in Equestrian sports. The concentration of prohibited substances was in none of the samples high enough to cause an effect on the body of the horse. The poppy seed sample, which was obtained by conventional harvesting and cleaning methods, contained a very high Morphine concen...
Management of horses with focus on blanketing and clipping practices reported by members of the Swedish and Norwegian equestrian community.
Journal of animal science    April 6, 2017   Volume 95, Issue 3 1104-1117 doi: 10.2527/jas.2016.1146
Hartmann E, Bøe KE, Jørgensen GH, Mejdell CM, Dahlborn K.Limited information is available on the extent to which blankets are used on horses and the owners' reasoning behind clipping the horse's coat. Research on the effects of those practices on horse welfare is scarce but results indicate that blanketing and clipping may not be necessary from the horse's perspective and can interfere with the horse's thermoregulatory capacities. Therefore, this survey collected robust, quantitative data on the housing routines and management of horses with focus on blanketing and clipping practices as reported by members of the Swedish and Norwegian equestrian com...
Maxillary nerve blocks in horses: an experimental comparison of surface landmark and ultrasound-guided techniques.
Veterinary anaesthesia and analgesia    April 6, 2017   Volume 44, Issue 4 951-958 doi: 10.1016/j.vaa.2016.09.005
Stauffer S, Cordner B, Dixon J, Witte T.The aim of this preliminary proof-of-concept study was to evaluate and compare the success and complication rate of infiltration of the maxillary nerve of cadaver heads using previously described surface landmarks, standard ultrasound and a novel needle guidance positioning ultrasound system (SonixGPS). Methods: Prospective, anatomical, method-comparison study. Methods: Thirty-eight equine cadaver heads. Methods: Twenty-six veterinary students performed the three methods consecutively on cadaver heads using an 18 gauge, 8.9 cm spinal needle and 0.5 mL iodinated contrast medium. Computed tomog...
Detecting taxonomic and phylogenetic signals in equid cheek teeth: towards new palaeontological and archaeological proxies.
Royal Society open science    April 5, 2017   Volume 4, Issue 4 160997 doi: 10.1098/rsos.160997
Cucchi T, Mohaseb A, Peigné S, Debue K, Orlando L, Mashkour M.The Plio-Pleistocene evolution of and the subsequent domestication of horses and donkeys remains poorly understood, due to the lack of phenotypic markers capable of tracing this evolutionary process in the palaeontological/archaeological record. Using images from 345 specimens, encompassing 15 extant taxa of equids, we quantified the occlusal enamel folding pattern in four mandibular cheek teeth with a single geometric morphometric protocol. We initially investigated the protocol accuracy by assigning each tooth to its correct anatomical position and taxonomic group. We then contrasted the ph...
Horses in Denmark Are a Reservoir of Diverse Clones of Methicillin-Resistant and -Susceptible Staphylococcus aureus.
Frontiers in microbiology    April 3, 2017   Volume 8 543 doi: 10.3389/fmicb.2017.00543
Islam MZ, Espinosa-Gongora C, Damborg P, Sieber RN, Munk R, Husted L, Moodley A, Skov R, Larsen J, Guardabassi L.Denmark is a country with high prevalence of livestock-associated methicillin-resistant Staphylococcus aureus (MRSA) clonal complex (CC) 398 in pigs. Even though pig farming is regarded as the main source of human infection or colonization with MRSA CC398, 10-15% of the human cases appear not to be linked to pigs. Following the recent reports of MRSA CC398 in horses in other European countries and the lack of knowledge on S. aureus carriage in this animal species, we carried out a study to investigate whether horses constitute a reservoir of MRSA CC398 in Denmark, and to gain knowledge on the ...
UK to get a centralised national database for horses this summer.
The Veterinary record    April 2, 2017   Volume 180, Issue 13 320-321 doi: 10.1136/vr.j1569
No abstract available
Characterization of the zoonotic potential of Toxoplasma gondii in horses from Rio de Janeiro State.
Acta tropica    April 2, 2017   Volume 171 159-162 doi: 10.1016/j.actatropica.2017.03.036
Venturi SS, da Silva AF, Frazão-Teixeira E, de Oliveira FCR, Consalter A, Padilha FGF, Fonseca ABM, Ferreira AMR.The aim of this study was to perform a survey on the prevalence of anti-Toxoplasma gondii antibodies in horses from Rio de Janeiro State, Brazil. From 2012 to 2013, a total of 624 blood samples were collected from horses from the eight regions comprising Rio de Janeiro State (Baixadas Litorâneas, Serrana, Norte Fluminense, Noroeste Fluminense, Centro-Sul, Metropolitana, Médio Paraíba, and Costa Verde). All sera samples were tested for anti-T. gondii antibodies by performing the modified agglutination test with a cut-off of 1:25. Positive serology for T. gondii was detected in 22.8% (142/624...
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