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Animals : an open access journal from MDPI2023; 13(16); 2663; doi: 10.3390/ani13162663

Current and Future Advances in the Detection and Surveillance of Biosecurity-Relevant Equine Bacterial Diseases Using Loop-Mediated Isothermal Amplification (LAMP).

Abstract: Horses play an important role throughout the world, whether for work, culture, or leisure, providing an ever-growing significant contribution to the economy. The increase in importation and movement of horses, both nationally and internationally, has inevitably allowed for the global equine industry to grow. Subsequently, however, the potential for transmission of fatal equine bacterial diseases has also escalated, and devasting outbreaks continue to occur. To prevent such events, disease surveillance and diagnosis must be heightened throughout the industry. Current common, or "gold-standard" techniques, have shown to be inadequate at times, thus requiring newer technology to impede outbreaks. Loop-mediated isothermal amplification (LAMP) has proven to be a reliable, rapid, and accessible tool in both diagnostics and surveillance. This review will discuss equine bacterial diseases of biosecurity relevance and their current diagnostic approaches, as well as their respective LAMP assay developments. Additionally, we will provide insight regarding newer technology and advancements associated with this technique and their potential use for the outlined diseases.
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Publication Date: 2023-08-18 PubMed ID: 37627456PubMed Central: PMC10451754DOI: 10.3390/ani13162663Google Scholar: Lookup
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  • Review

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The research article is about the latest progress and future potential of Loop-Mediated Isothermal Amplification (LAMP) in detecting, tracking, and controlling equine bacterial diseases relevant to biosecurity.

Understanding the Context

  • The paper emphasizes the globally increasing significance of the horse industry for work, sports, cultural reasons, and economic contribution. With the amplifying importation and movement of horses, the global horse industry is thriving.
  • However, the increased movement of horses also heightens the risk of transmitting fatal equine bacterial diseases, which can result in severe outbreaks. As such, it calls for enhanced disease detection and monitoring mechanisms.
  • The industry’s current diagnostic techniques, often referred to as “gold-standard,” have proven to be insufficient at times. This inefficiency necessitates the introduction of advanced technology to prevent disease outbreaks.

Loop-Mediated Isothermal Amplification (LAMP)

  • LAMP emerges as a reliable, quick, and accessible tool for disease diagnosis and surveillance in the horse industry.
  • this research article particularly reviews equine bacterial diseases related to biosecurity, the present diagnostic methodologies, and their respective developments in LAMP assays.

Significance and Future Developments

  • Apart from this, the researchers in the paper also shed light on the latest advancements and technologies related to LAMP, intending to use them for the outlined diseases.
  • The adoption of advanced techniques like LAMP can greatly enhance our capabilities in detecting and mitigating horse diseases at an early stage, thereby ensuring biosecurity.

Cite This Article

APA
Knox A, Zerna G, Beddoe T. (2023). Current and Future Advances in the Detection and Surveillance of Biosecurity-Relevant Equine Bacterial Diseases Using Loop-Mediated Isothermal Amplification (LAMP). Animals (Basel), 13(16), 2663. https://doi.org/10.3390/ani13162663

Publication

Animals : an open access journal from MDPI
ISSN: 2076-2615
NlmUniqueID: 101635614
Country: Switzerland
Language: English
Volume: 13
Issue: 16
PII: 2663

Researcher Affiliations

Knox, Alexandra
  • Department of Animal, Plant and Soil Sciences, Centre for AgriBioscience, La Trobe University, Bundoora, VIC 3082, Australia.
Zerna, Gemma
  • Department of Animal, Plant and Soil Sciences, Centre for AgriBioscience, La Trobe University, Bundoora, VIC 3082, Australia.
Beddoe, Travis
  • Department of Animal, Plant and Soil Sciences, Centre for AgriBioscience, La Trobe University, Bundoora, VIC 3082, Australia.

Grant Funding

  • na / Cooperative Research Centres Project (CRC-P)
  • na / Defence Science Institute

Conflict of Interest Statement

The authors declare no conflict of interest.

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