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Journal of the American Veterinary Medical Association.
Publisher:
[American Veterinary Medical Association,. Schaumburg, Ill. : American Veterinary Medical Association (1975)
Frequency: Semimonthly
Country: United States
Language: English
Author(s):
American Veterinary Medical Association.
Start Year:1915 -
Identifiers
| ISSN: | 0003-1488 (Print) 1943-569X (Electronic) 0003-1488 (Linking) |
| NLM ID: | 7503067 |
| (OCoLC): | 01084791 |
| (DNLM): | J12340000(s) |
| Coden: | JAVMA4 |
| LCCN: | 16022549 |
| Classification: | W1 JO911J |
Use of the meridian test for the detection of equine herpesvirus type 1 infection in horses with decreased performance. To evaluate use of the acupuncture meridian test for detection of recent or recently reactivated equine herpesvirus type 1 (EHV-1) infection in horses with decreased performance. Methods: Case-control study. Methods: 40 horses. Methods: Physical and neurologic examinations were performed, and acupuncture points on the bladder meridian were tested for sensitivity reactions in case and control horses. Polymerase chain reaction assays were performed to determine whether EHV-1 or equine herpesvirus type 4 (EHV-4) DNA could be detected in peripheral blood mononuclear cells. Complement fixation (CF)...
Effects of intravenous administration of dimethyl sulfoxide on cardiopulmonary and clinicopathologic variables in awake or halothane-anesthetized horses. To evaluate the cardiopulmonary and clinicopathologic effects of rapid IV administration of dimethyl sulfoxide (DMSO) in awake and halothane-anesthetized horses. Methods: Prospective study. Methods: 6 adult horses. Methods: Horses received IV infusion of 5 L of a balanced electrolyte solution with and without 1 g/kg (0.45 g/lb) of 10% DMSO solution when they were awake and anesthetized with halothane (4 treatments/horse). Arterial and venous blood samples were collected immediately before and at intervals during or after fluid administration and analyzed for blood gases and hematologic and ser...
Humoral response to West Nile virus vaccination in alpacas and llamas. To determine humoral responses to an equine West Nile virus (WNV) vaccine in healthy alpacas and llamas and compare responses in alpacas and llamas with responses in horses. Methods: Clinical trial. Methods: 28 alpacas, 56 llamas, and 16 horses. Methods: Horses received 2 vaccinations at 4-week intervals, and alpacas and llamas received 3 vaccinations at 3-week intervals. Fifty-five llamas received a fourth vaccination 3 weeks after the third. Blood samples were collected immediately prior to each vaccination, 3 weeks after the last vaccination for alpacas and llamas, and 4 weeks after the las...
Hypercalcemia and high serum parathyroid hormone-related protein concentration in a horse with multiple myeloma. A 13-year-old gelding was examined because of weight loss, hyperglobulinemia, and hypercalcemia. Possible causes of hypercalcemia that were considered included renal failure, primary hyperparathyroidism, vitamin D toxicosis, and malignancy. There was no history of vitamin D ingestion, and serum creatinine and parathyroid hormone concentrations were normal, making renal failure and primary hyperparathyroidism unlikely. The hypercalcemia was suspected to be a result of malignancy, but thorough testing did not reveal any neoplastic disease. Eight months later, serum parathyroid hormone-related pr...
Outcome of equids with clinical signs of West Nile virus infection and factors associated with death. To determine outcome of equids in the western United States with clinical signs of West Nile virus (WNV) infection and identify factors associated with risk of death in infected equids. Methods: Cross-sectional study. Methods: 484 equids in Nebraska and Colorado. Methods: Owners of 484 equids with laboratory-confirmed West Nile virus infection in Nebraska and Colorado were contacted by telephone, and a questionnaire was used to obtain information on signalment, management, clinical signs, date of disease onset, duration of disease, WNV vaccination status, and health status at the time of the i...
Risk factors associated with fecal Salmonella shedding among hospitalized horses with signs of gastrointestinal tract disease. To estimate prevalence of and identify risk factors for fecal Salmonella shedding among hospitalized horses with signs of gastrointestinal tract disease. Methods: Cross-sectional study. Methods: 465 hospitalized horses with gastrointestinal tract disease. Methods: Horses were classified as positive or negative for fecal Salmonella shedding during hospitalization by means of standard aerobic bacteriologic methods. The relationship between investigated exposure factors and fecal Salmonella shedding was examined by means of logistic regression. Results: The overall prevalence of fecal Salmonella ...
Investigation of an outbreak of encephalomyelitis caused by West Nile virus in 136 horses. To describe an outbreak of encephalomyelitis caused by West Nile virus (WNV) in horses in northern Indiana. Methods: Case series. Methods: 170 horses. Methods: Horses with clinical signs suggestive of encephalomyelitis caused by WNV were examined. Date, age, sex, breed, and survival status were recorded. Serum samples were tested for anti-WNV antibodies, and virus isolation was attempted from samples of brain tissue. Climate data from local weather recording stations were collected. An epidemic curve was constructed, and case fatality rate was calculated. Results: The most common clinical sign...
Excision as treatment of dermal melanomatosis in horses: 11 cases (1994-2000). To determine whether excision was an acceptable treatment for dermal melanomatosis in horses. Methods: Retrospective study. Methods: 11 horses with dermal melanomatosis involving the perineal, perianal, or perirectal region or ventral surface of the tail in which treatment consisted of tumor excision. Methods: Medical records were reviewed. Follow-up information was obtained from owners through telephone interviews. Results: 9 of the 11 horses were alive at the time of follow-up interviews. None of the horses had regrowth at the surgery site where the primary tumor was removed. There were no c...
Association between race history and risk of superficial digital flexor tendon injury in Thoroughbred racehorses. To determine whether race history, including the number of races and total race distance, was associated with risk of superficial digital flexor tendon (SDFT) injury in Thoroughbred racehorses in Japan. Methods: Matched case-control study. Methods: 515 Thoroughbred racehorses (case horses) that sustained an SDFT injury during training or racing in Japan during 2002 and 951 horses (control horses) without SDFT injury that were matched with case horses on the basis of age and month of the latest race. Methods: Variables related to race history were compared between case and control horses by mea...
Idiopathic gastroesophageal reflux disease in an adult horse. Chronic gastroesophageal reflux disease was diagnosed in a 22-year-old female Tennessee Walking Horse that had signs of bruxism and ptyalism. Esophageal ulceration was detected via endoscopy. Compared with the damage to the proximal portions of the esophagus, the severity of the ulceration increased toward the gastroesophageal junction. Esophageal ulceration attributable to chronic gastric acid reflux is usually secondary to pyloric outflow obstruction in horses. In the horse of this report, there was no evidence of either a chronic pyloric or duodenal obstruction that could have resulted in e...
Acute recumbency associated with Anaplasma phagocytophilum infection in a horse. An 11-year-old Hanoverian-cross gelding was evaluated because of acute onset of ataxia, recumbency, and fever. At the stable, this and other horses had recently been infested with ticks. Results of analysis of a sample of CSF were within reference limits, but hematologic abnormalities included lymphopenia, thrombocytopenia, mild anemia, and intracytoplasmic inclusion bodies in neutrophils that were consistent with Anaplasma phagocytophilum (previously Ehrlichia equi). Results of serum biochemical analyses were characteristic of infection and included high, unconjugated bilirubin concentration....
Use of magnetic resonance imaging identify suspensory desmitis and adhesions between exostoses of the second metacarpal bone and the suspensory ligament in four horses. Four horses were examined because of chronic forelimb lameness. In all horses, the cause of the lameness was localized to the metacarpus by means of physical examination and diagnostic anesthesia, and radiography of the affected limb revealed a small exostosis of the second metacarpal bone. Magnetic resonance imaging revealed suspensory desmitis in the region of this exostosis in all 4 horses. In addition, an abnormal area of low signal intensity, suggestive of an adhesion, was seen between the exostosis and the suspensory ligament. In all horses, an adhesion between the suspensory ligament an...
Arthroscopic findings in horses with subtle radiographic evidence of osteochondral lesions of the medial femoral condyle: 15 cases (1995-2002). To determine arthroscopic findings in lame horses with subtle radiographic lesions of the medial femoral condyle. Methods: Retrospective study. Methods: 15 horses examined because of lameness that had subtle radiographic evidence of osteochondral lesions involving the medial femoral condyle in at least 1 joint. Methods: Medical records were reviewed, and results of physical examination, radiography, and arthroscopy were recorded. Follow-up information was obtained through reexamination of the horses or telephone conversations with the referring veterinarians, owners, or trainers. Results: Lame...
Gracilis muscle injury as a cause of lameness in two horses. Injury to the gracilis muscle can cause acute, severe lameness in horses. Two female Quarter Horses that were used for barrel racing sustained gracilis muscle tear injuries. The site of injury was localized by direct infiltration of the area with mepivacaine. The extent of muscle tearing and seroma formation was determined via ultrasonographic evaluation. One horse developed fibrotic myopathy approximately 3 months after the original injury and underwent surgery to transect a palpable fibrous band at the previous injury site. Both horses returned to barrel racing 5 to 6 months after the injury...
Radiotherapy of a recurrent ossifying fibroma in the paranasal sinuses of a horse. A 7-year-old female Thoroughbred was admitted with a history of labored breathing, stridor, and exercise intolerance. Examination revealed a mass in the left paranasal sinuses that was determined to be an ossifying fibroma. Initial treatment consisted of surgical removal of the mass alone; however, the mass recurred 9 months after surgery. The mass was again removed, and adjunctive radiotherapy consisting of 3,000 cGy of cobalt radiation was administered. This time, the tumor did not recur for > 6 years. A third surgery was performed to remove the mass, and adjunctive radiotherapy consisting o...
Use of distraction osteogenesis for the correction of deviated nasal septum and premaxilla in a horse. A 13-month-old female Andalusian was evaluated because of a congenital left deviation of the maxilla and nasal septum, which had resulted in a gross malocclusion of the maxillary incisor teeth. Surgical correction of a deviated nasal septum and premaxilla in a horse was first reported in 1978 and involved a pre-maxilla osteotomy and use of an autogenous rib graft, with a nasal septum osteotomy performed in a second surgery; to the authors' knowledge, no alternative surgical treatments have since been described. In this horse, a new surgical treatment by distraction osteogenesis without nasal s...
In vitro study of heat production during power reduction of equine mandibular teeth. To measure the amount of heat generated during 3 methods of equine dental reduction with power instruments. Methods: In vitro study. Methods: 30 premolar and molar teeth removed from mandibles of 8 equine heads collected at an abbatoir. Methods: 38-gauge copper-constantan thermocouples were inserted into the lingual side of each tooth 15 mm (proximal) and 25 mm (distal) from the occlusal surface, at a depth of 5 mm, which placed the tip close to the pulp chamber. Group-NC1 (n = 10) teeth were ground for 1 minute without coolant, group-NC2 (10) teeth were ground for 2 minutes without coolant, a...
Treatment for a severe reaction to intravenous administration of diatrizoate in an anesthetized horse. A mature horse developed acute signs of bronchoconstriction causing hypoxemia and hypercapnia during anesthesia for computerized tomography of the maxillary sinus after i.v. administration of diatrizoate contrast medium. The horse was treated with aerosolized albuterol, atropine, and oxygen insufflation and recovered uneventfully despite severe hypoxemia and low hemoglobin saturation. The horse's condition continued to improve after treatment, and the horse was discharged with no further complications. Caution is advised with the use of contrast media in anesthetized horses.
Treatment of suppurative facial cellulitis and panniculitis caused by Corynebacterium pseudotuberculosis in two horses. Two horses were examined for large head wounds suspected to be the result of trauma and characterized by extensive necrosis of the skin and subcutaneous tissue, with abundant purulent exudate. Corynebacterium pseudotuberculosis was isolated from the facial wounds in both horses. Histopathologic examination revealed severe suppurative cellulitis and panniculitis with fistulous tracts and granulation tissue in 1 horse. Both horses were treated with local wound care, nonsteroidal anti-inflammatory drugs, and administration of antimicrobials. The concept of moist wound care was used in the second ...
Evaluation of suspected pituitary pars intermedia dysfunction in horses with laminitis. To determine prevalence and clinical features of pituitary pars intermedia dysfunction (PPID) in horses with laminitis. Methods: Case series. Methods: 40 horses with laminitis. Methods: Horses with laminitis that survived an initial episode of pain and were not receiving medications known to alter the hypothalamic-pituitary-adrenal axis were tested for PPID by evaluation of endogenous plasma ACTH concentration. Signalment, suspected cause, month of onset and duration of laminitis, Obel grade of lameness, pedal bone rotation, physical examination findings, results of endocrine function tests, t...
Pericarditis and pleuritis caused by Corynebacterium pseudotuberculosis in a horse. A 13-year-old Oldenburg mare was evaluated for lethargy and signs of mild colic. Pericardial tamponade caused by fibrinoeffusive pericarditis was diagnosed. Cytologic and biochemical evaluation of pericardial fluid was consistent with a septic effusion. Corynebacterium pseudotuberculosis, the cause of pigeon fever, was identified by bacteriologic culture of pericardial fluid. Drainage and lavage of the pericardial sac, local (intrapericardial) and systemic antimicrobial treatment, and subsequent corticosteroid treatment resulted in a successful outcome in this horse. To the authors' knowledge,...
Thyroid function and pregnancy status in broodmares. To determine whether thyroid function was associated with pregnancy status in broodmares. Methods: Prospective study. Methods: 79 Thoroughbred and Standardbred broodmares between 2 and 22 years old. Methods: Serum triiodothyronine (T3) concentration was measured before and 2 hours after i.v. administration of thyrotropin releasing hormone (TRH), and serum thyroxine (T4) concentration was measured before and 4 hours after TRH administration. Pregnancy status was monitored by means of transrectal ultrasonography beginning 16 days after ovulation. Results: Baseline T3 and T4 concentrations varied...
Use of chemotherapy for treatment of a mixed-cell thoracic lymphoma in a horse. A 4-year-old Oldenburg mare was evaluated because of signs of lower airway disease and subsequently developed bilateral pleural effusion. Neoplastic cells were not identified in the fluid sample obtained via the initial thoracocentesis. A thoracic mass was detected radiographically, but its location prevented collection of a tissue sample. A diagnosis of lymphoma was made on the basis of results of immunophenotyping of pleural fluid specimens. Treatment of thoracic lymphoma in horses has been attempted, but there are limited data regarding chemotherapeutic-induced remission. In this horse, rem...
Bacterial meningitis and brain abscesses secondary to infectious disease processes involving the head in horses: seven cases (1980-2001). To determine clinical features of horses with bacterial meningitis or brain abscesses secondary to infectious disease processes involving the head. Methods: Retrospective study. Methods: 7 adult horses. Methods: Medical records of Tufts University, the University of Pennsylvania, and the Livestock Disease Diagnostic Center (Lexington, Ky) were reviewed to identify adult (> 12 months old) horses in which a postmortem diagnosis of bacterial meningitis or brain abscess had been made. Horses were included in the study if an intracranial infection was confirmed, the horse had a primary infectious d...
