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Topic:Animal Health

Animal Health encompasses a broad range of topics focused on maintaining and improving the well-being of equine species. This field addresses various aspects of horse care, including disease prevention, diagnosis, treatment, and management of health conditions. Key areas of interest include equine nutrition, vaccination protocols, parasite control, dental care, and the management of chronic conditions such as laminitis and colic. Additionally, animal health research in horses investigates the impact of exercise and training on physical health, the role of genetics in disease susceptibility, and the development of new therapeutic approaches. This page compiles peer-reviewed research studies and scholarly articles that explore the latest advancements, challenges, and best practices in preserving and enhancing the health of horses.
Techniques and Accuracy of Abdominal Ultrasound in Gastrointestinal Diseases of Horses and Foals.
The Veterinary clinics of North America. Equine practice    February 7, 2018   Volume 34, Issue 1 25-38 doi: 10.1016/j.cveq.2017.11.001
Cribb NC, Arroyo LG.Diagnostic ultrasonography has been used as a test to determine the presence or absence of gastrointestinal disease in horses and foals. General techniques and anatomic landmarks are reviewed. Many clinical reports that have included diagnostic ultrasound as part of their diagnostic process and accuracy studies are necessary to determine the usefulness of diagnostic ultrasound in clinical practice.
Poisoning by Brunfelsia uniflora in sheep and donkeys. Mello GW, Riet-Correa F, Batista MC, Carvalho CJ, Dias AC, Franklin FL, Silva SM, Dias A.Farmers in the State of Piauí in northeastern Brazil reported nervous signs in ruminants and donkeys after ingestion of Brunfelsia uniflora at the start of the rainy season when the plant is flowering. Leaves of the plant, collected at the start or at the end of the rainy season, were administered in single doses of 5-20 g/kg body weight to 8 sheep and 3 donkeys. Two sheep and 1 donkey that ingested 10 g/kg of the plant in November at the start of the rainy season, when the plant was flowering, developed severe convulsions and diarrhea. One sheep was euthanized and autopsied, and no significa...
Improving working equine welfare in ‘hard-win’ situations, where gains are difficult, expensive or marginal.
PloS one    February 6, 2018   Volume 13, Issue 2 e0191950 doi: 10.1371/journal.pone.0191950
Pritchard J, Upjohn M, Hirson T.Brooke is a non-government organisation with working equine welfare programmes across Africa, Asia and Latin America. In 2014, staff from ten country programmes were asked to identify 'no-win' situations (subsequently reframed as 'hard-wins')-where improving equine welfare is proving difficult, expensive and/or marginal-in order to inform strategic decisions on how to approach, manage and mitigate for such situations. The Delphi-type consultation process had three phases. Round 1 posed five questions in the form of a workshop, survey and semi-structured interviews. Round 2 re-presented key the...
Congenital Hepatic Fibrosis in a Purebred Spanish Horse Foal: Pathology and Genetic Studies on PKHD1 Gene Mutations.
Veterinary pathology    February 5, 2018   Volume 55, Issue 3 457-461 doi: 10.1177/0300985817754122
Molín J, Asín J, Vitoria A, Sanz A, Gimeno M, Romero A, Sánchez J, Pinczowski P, Vázquez FJ, Rodellar C, Luján L.A 1-month-old Purebred Spanish Horse (PSH) foal presented with progressive hepatic failure culminating in death. Hepatic lesions were consistent with congenital hepatic fibrosis (CHF). Genetic studies in the PKHD1 gene in the affected foal revealed that it was heterozygous for the 2 previously described single-nucleotide polymorphisms (SNPs) linked to CHF in Swiss Franches-Montagnes (SFM) horses. In addition, 2 novel mutations were detected, the foal being homozygous for one of them and heterozygous for the other. Genetic studies in a healthy PSH population ( n = 35) showed a 3-fold higher gen...
Prevalence of Rhodococcus equi from the nasal cavity of 1010 apparently healthy horses.
Equine veterinary journal    February 5, 2018   Volume 50, Issue 5 667-671 doi: 10.1111/evj.12804
Gressler LT, Machado G, da Silveira BP, Cohen ND, Corbellini LG, Leotti VB, Diehl GN, Dos Santos LC, de Vargas AC.Rhodococcus equi is an important cause of foal pneumonia. While its isolation from different sources has been widely evaluated, there is a need to better understand the R. equi epidemiology from samples of the nasal cavity of healthy horses. Objective: To determine the prevalence of R. equi from the nasal cavity of healthy horses, along with its virulence profile, antimicrobial susceptibility and environmental variables associated. Methods: Cross-sectional study. Methods: Swabs from the nasal cavity of 1010 apparently healthy horses from 341 farms were submitted for bacteriological analyses. T...
Short-term tolerance of equine spermatozoa to various abiotic factors.
Reproduction in domestic animals = Zuchthygiene    February 5, 2018   Volume 53, Issue 2 534-544 doi: 10.1111/rda.13142
Pérez-Marín CC, Requena FD, Arando A, Requena L, Requena F, Agüera EI.The aim of this study was to determine the effects of various abiotic factors, such as light, physical stress (pipetting) and thermal shock, on the quality of fresh and cooled equine sperm. In experiment I, four sperm aliquots were subjected to different light exposures: (i) protected control samples (CTRL), (ii) exposed to UV light at 10 cm (UV10), (iii) exposed to UV light at 20 cm (UV20) and (iv) exposed to laboratory lighting (LAB). In experiment II, four semen aliquots were subjected to repeated pipetting for 0, 10, 20 and 30 times (CTRL, P10, P20 and P30, respectively). In experiment I...
Stress level effects on sport performance during trotting races in Spanish Trotter Horses.
Research in veterinary science    February 4, 2018   Volume 118 86-90 doi: 10.1016/j.rvsc.2018.01.017
Negro S, Bartolomé E, Molina A, Solé M, Gómez MD, Valera M.The stress level is suggested to have a negative effect on horses during equestrian competitions, specifically in trotter racing. The main objectives of this study were to measure stress levels in Spanish Trotter Horse races with a reliable non-invasive method, and determining the threshold level of stress that leads to the best performance results and also shows when the stress perceived by the horse becomes distress. One hundred and thirty individuals were evaluated, measuring their performance (based on racing time per kilometre (TPK)) and their stress (based on eye temperature, assessed wi...
Strangvac: A recombinant fusion protein vaccine that protects against strangles, caused by Streptococcus equi.
Vaccine    February 2, 2018   Volume 36, Issue 11 1484-1490 doi: 10.1016/j.vaccine.2018.01.030
Robinson C, Frykberg L, Flock M, Guss B, Waller AS, Flock JI.The host-restricted pathogen Streptococcus equi causes strangles in the horse, which is characterised by abscessation of the lymph nodes of the head and neck. The disease is endemic throughout the world causing considerable welfare and economic cost to the horse industry. Here we report the results of three studies where ponies were vaccinated with combinations of recombinant fusion proteins to optimise vaccine production and the level of protection conferred. Optimal protection was conferred by a prototype multicomponent subunit vaccine, Strangvac 4, which contained eight proteins CNE, SclC, ...
Comparison of incisional bursting strength of 2-strand continuous crossing and simple continuous patterns for closure of the equine linea alba.
The Canadian veterinary journal = La revue veterinaire canadienne    February 2, 2018   Volume 59, Issue 2 171-173 
Souza CRS, Farnsworth KD, Ragle CA.The objective of this study was to assess and compare the bursting pressure and mode of failure of a 2-strand continuous crossing suture pattern and a simple continuous suture pattern for closure of the equine linea alba. No difference in bursting strength or mode of failure was found between the 2 suture patterns. Comparaison de la force d’éclatement des incisions des sutures simples continues et des sutures croisées continues à deux fils pour la fermeture de la linea alba des équidés. Cette étude avait pour objectif d’évaluer et de comparer la pression d’éclatement et le mode d...
The contribution of total and free iodothyronines to welfare maintenance and management stress coping in Ruminants and Equines: Physiological ranges and reference values.
Research in veterinary science    February 2, 2018   Volume 118 134-143 doi: 10.1016/j.rvsc.2018.01.025
Ferlazzo A, Cravana C, Fazio E, Medica P.In order to acquire a pattern of thyroid involvement in welfare maintenance in Ruminants and Equines, this review summarizes data concerning the reference values of total and free iodothyronines and their modifications in physiological conditions and in different management conditions (pregnancy, lactation, weaning, growth, isolation, restraint, shearing, confinement and transportation). Thyroidal and extrathyroidal tissues efficiently respond to management practices, giving a differentiated contribution to circulating iodothyronine changes. The hormonal response could be mainly attributed to ...
Evaluation of conjugated linoleic acid supplementation on markers of joint inflammation and cartilage metabolism in young horses challenged with lipopolysaccharide.
Journal of animal science    February 1, 2018   Volume 96, Issue 2 579-590 doi: 10.1093/jas/skx076
Bradbery AN, Coverdale JA, Vernon KL, Leatherwood JL, Arnold CE, Dabareiner RA, Kahn MK, Millican AA, Welsh TH.Seventeen yearling Quarter Horses were used in a randomized complete block design for a 56-d trial to determine ability of dietary CLA to mitigate joint inflammation and alter cartilage turnover following an inflammatory insult. Horses were blocked by age, sex, and BW, and randomly assigned to dietary treatments consisting of commercial concentrate offered at 1% BW (as-fed) supplemented with either 1% soybean oil (CON; n = 6), 0.5% soybean oil and 0.5% CLA (LOW; n = 5; 55% purity; Lutalin, BASF Corp., Florham Park, NJ), or 1% CLA (HIGH; n = 6) top-dressed daily. Horses were fed individually ev...
On the brink of daily clinical application of objective gait analysis: What evidence do we have so far from studies using an induced lameness model?
Veterinary journal (London, England : 1997)    January 31, 2018   Volume 234 11-23 doi: 10.1016/j.tvjl.2018.01.006
Serra Bragança FM, Rhodin M, van Weeren PR.Quantitative gait analysis has the potential to offer objective and unbiased gait information that can assist clinical decision-making. In recent years, a growing number of gait analysis systems have come onto the market, highlighting the demand for such technology in equine orthopaedics. However, it is imperative that the measured variables which are used as outcome parameters are supported by scientific evidence and that the interpretation of such measurements is backed by a proper understanding of the biomechanical principles of equine locomotion. This review, which is based on studies on e...
Genetic analysis of the Hungarian draft horse population using partial mitochondrial DNA D-loop sequencing.
PeerJ    January 31, 2018   Volume 6 e4198 doi: 10.7717/peerj.4198
Csizmár N, Mihók S, Jávor A, Kusza S.The Hungarian draft is a horse breed with a recent mixed ancestry created in the 1920s by crossing local mares with draught horses imported from France and Belgium. The interest in its conservation and characterization has increased over the last few years. The aim of this work is to contribute to the characterization of the endangered Hungarian heavy draft horse populations in order to obtain useful information to implement conservation strategies for these genetic stocks. Methods: To genetically characterize the breed and to set up the basis for a conservation program, in the present study a...
Free and bound cortisol in plasma and saliva during ACTH challenge in dairy cows and horses.
Journal of animal science    January 30, 2018   Volume 96, Issue 1 76-84 doi: 10.1093/jas/skx008
Schwinn AC, Sauer FJ, Gerber V, Bruckmaier RM, Gross JJ.Cortisol levels reflect hypothalamic-pituitary-adrenocortical (HPA) axis activity. While most plasma cortisol is supposed to be bound to the soluble corticosteroid-binding globulin (CBG), only free cortisol (FC) actively regulates metabolic and immunological processes. We aimed to establish a multispecies suitable method to assess FC in cows and horses which in combination with total cortisol (TC) allows interpreting proportional changes of cortisol in saliva as well as in blood in response to a standardized HPA axis activation via ACTH. We further investigated if the ratios of cortisol fracti...
Extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli and Acinetobacter baumannii among horses entering a veterinary teaching hospital: The contemporary “Trojan Horse”.
PloS one    January 30, 2018   Volume 13, Issue 1 e0191873 doi: 10.1371/journal.pone.0191873
Walther B, Klein KS, Barton AK, Semmler T, Huber C, Wolf SA, Tedin K, Merle R, Mitrach F, Guenther S, Lübke-Becker A, Gehlen H.Pathogens frequently associated with multi-drug resistant (MDR) phenotypes, including extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae (ESBL-E) and Acinetobacter baumannii isolated from horses admitted to horse clinics, pose a risk for animal patients and personnel in horse clinics. To estimate current rates of colonization, a total of 341 equine patients were screened for carriage of zoonotic indicator pathogens at hospital admission. Horses showing clinical signs associated with colic (n = 233) or open wounds (n = 108) were selected for microbiological examination of nost...
Effect of trotting speed on kinematic variables measured by use of extremity-mounted inertial measurement units in nonlame horses performing controlled treadmill exercise.
American journal of veterinary research    January 24, 2018   Volume 79, Issue 2 211-218 doi: 10.2460/ajvr.79.2.211
Cruz AM, Vidondo B, Ramseyer AA, Maninchedda UE.OBJECTIVE To assess effects of speed on kinematic variables measured by use of extremity-mounted inertial measurement units (IMUs) in nonlame horses performing controlled exercise on a treadmill. ANIMALS 10 nonlame horses. PROCEDURES 6 IMUs were attached at predetermined locations on 10 nonlame Franches Montagnes horses. Data were collected in triplicate during trotting at 3.33 and 3.88 m/s on a high-speed treadmill. Thirty-three selected kinematic variables were analyzed. Repeated-measures ANOVA was used to assess the effect of speed. RESULTS Significant differences between the 2 speeds were ...
Modulation of chaperone-like and membranolytic activities of major horse seminal plasma protein HSP-1/2 by L-carnitine.
Journal of biosciences    January 24, 2018   Volume 42, Issue 3 469-479 doi: 10.1007/s12038-017-9693-6
Sudheer Kumar C, Swamy MJ.The major protein of horse seminal plasma, HSP-1/2, exhibits membranolytic and chaperone-like activities and plays a crucial role in regulating sperm capacitation. L-Carnitine is a small polar molecule present in high concentrations in mammalian seminal plasma. The present results demonstrate that L-carnitine binds to HSP-1/2 and increases its thermal stability, enhances cooperativity of its chemical unfolding and decreases both chaperone-like and membranolytic activities of this protein. The HSP-1/2-L-carnitine complex exhibits anti-oxidative behaviour by inhibiting the production of hydroxyl...
Exclusion of adrenoceptor alpha 2 variants in a horse insensitive to medetomidine.
Animal genetics    January 23, 2018   Volume 49, Issue 2 141 doi: 10.1111/age.12636
Schmutz I, Jagannathan V, Diez Bernal S, Lanz S, Kalbfleisch T, Leeb T, Spadavecchia C.No abstract available
Plasticity effect of rider-horse interaction on genetic evaluations for Show Jumping discipline in sport horses.
Journal of animal breeding and genetics = Zeitschrift fur Tierzuchtung und Zuchtungsbiologie    January 23, 2018   Volume 135, Issue 2 138-148 doi: 10.1111/jbg.12315
Bartolomé E, Menéndez-Buxadera A, Molina A, Valera M.To obtain a sport horse that excels in the highest levels of competition, breeders must take into account certain genetic and environmental factors that could influence the sport horse's performance, such as the rider-horse interaction (RHI). The main aim of this study was to describe this interaction in a genetic model by modelling it in relation to the horse's age. A total of 31,129 sport results from Spanish Sport Horses were used from a total of 1,101 animals evaluated, and these were grouped in three age levels and had been ridden by 606 different riders. Only riders who had ridden more t...
Tick infestation on sheep, goat, horse and wild hare in Tamil Nadu.
Journal of parasitic diseases : official organ of the Indian Society for Parasitology    January 23, 2018   Volume 42, Issue 1 127-129 doi: 10.1007/s12639-018-0977-z
Soundararajan C, Nagarajan K, Muthukrishnan S, Arul Prakash M.The prevalence of tick infestation and their predilection sites on sheep, goat, horse and wild hare were studied at various places of Tamil Nadu, India. The prevalence of tick infestation in Madras red sheep, Tellicherry goat and horse was 77.11, 78.21 and 13.33%, respectively. Sheep were heavily infested with followed by , and . . The ticks from goats were identified as . , . , . and . . Horses were infested with and . . The ticks on wild hare () were identified as . and . . Wild hare acts as a source of infestation to the sheep and goats since these animals shared the same field.
Influences of dietary supplementation with Lepidium meyenii (Maca) on stallion sperm production and on preservation of sperm quality during storage at 5 °C.
Andrology    January 22, 2018   Volume 6, Issue 2 351-361 doi: 10.1111/andr.12463
Del Prete C, Tafuri S, Ciani F, Pasolini MP, Ciotola F, Albarella S, Carotenuto D, Peretti V, Cocchia N.Stallion semen is damaged by oxidative stress during cooling and transport. Semen processing and extenders have been tested to improve the fertilizing capacity of semen and to preserve semen during transport. Dietary supplementation with natural antioxidants has been proposed to prevent oxidative damages. In this study, for the first time, the effect of dietary supplementation with Lepidium meyenii (Maca) on the characteristics of fresh and chilled stallion semen was evaluated. Maca is a traditional Andean crop used as a nutraceutical for the fertility-enhancing properties that are linked with...
Pharmacokinetic evaluation and safety of topical 1% morphine sulfate application on the healthy equine eye.
Veterinary ophthalmology    January 19, 2018   Volume 21, Issue 5 516-523 doi: 10.1111/vop.12541
Gordon E, Stang BV, Heidel J, Poulsen KP, Cebra CK, Schlipf JW.To determine if corneal epithelial cell integrity is detrimentally affected by short-term administration of 1.0% morphine sulfate. Additionally, we sought to determine if topical 1.0% morphine applied to the equine cornea would result in ocular or systemic absorption. Methods: Six healthy horses. Methods: Morphine sulfate (1.0%) was applied topically to one eye every four hours for 72 h before horses were euthanized. Serum samples were collected at varying time points during the study and aqueous and vitreous humor were collected immediately after euthanasia. Morphine quantification in serum, ...
Genetic monitoring of horses in the Czech Republic: A large-scale study with a focus on the Czech autochthonous breeds.
Journal of animal breeding and genetics = Zeitschrift fur Tierzuchtung und Zuchtungsbiologie    January 19, 2018   Volume 135, Issue 1 73-83 doi: 10.1111/jbg.12313
Putnová L, Štohl R, Vrtková I.We propose the first comprehensive in-depth study monitoring horses in the Czech Republic. We scanned 9,289 animals from 44 populations for 17 equine STRs. Other equids analysed involved Equus przewalskii and Equus asinus. The total of 228 different alleles were detected, with the mean number of 13.4 per locus. The highest allelic richness (AR) was found in the Welsh Part Bred (6.01), followed by the Camargue (5.93) and Czech Sport Pony (5.91), whereas the Friesian exhibited the lowest AR (3.06). Interpopulation differences explained approximately nine per cent of the total genetic diversity. ...
Emergence of blaCTX-M-55 associated with fosA, rmtB and mcr gene variants in Escherichia coli from various animal species in France.
The Journal of antimicrobial chemotherapy    January 18, 2018   Volume 73, Issue 4 867-872 doi: 10.1093/jac/dkx489
Lupo A, Saras E, Madec JY, Haenni M.In Asian countries, blaCTX-M-55 is the second most common ESBL-encoding gene. blaCTX-M-55 frequently co-localizes with fosA and rmtB genes on epidemic plasmids, which remain sporadic outside Asia. During 2010-13, we investigated CTX-M-55-producing Escherichia coli isolates and their co-resistance to fosfomycin, aminoglycosides, fluoroquinolones and colistin as part of a global survey of ESBLs in animals in France. blaCTX-M-55, fosA, rmtB and plasmidic quinolone and colistin resistance genes were characterized by PCR, sequencing and hybridization experiments. Plasmids were classified according ...
Estimating the proportion of clinically diagnosed infectious and non-infectious animal diseases in Ganta Afeshum woreda, Eastern Tigray zone, Ethiopia.
BMC research notes    January 15, 2018   Volume 11, Issue 1 29 doi: 10.1186/s13104-018-3158-3
Tedla M, Gebreselassie M.This study was performed with the objective of identifying the proportion of emerging and endemic livestock diseases using cross sectional survey. Results: A total of 285 clinically diseased animals were presented to a veterinary clinic and diagnosed tentatively based on history, clinical sign, and simple laboratory diagnostics and from the study, actinomycosis (15.83%), mastitis (15%), tick infestation (10%), respiratory diseases (9.16%) and gastro intestinal parasitism (9.16%) were confirmed with higher proportion in large animals. Pasteurollosis (38, 31%), contagious ecthyma (12, 10%), tick...
Pharmacokinetics, pharmacodynamics and clinical use of trazodone and its active metabolite m-chlorophenylpiperazine in the horse.
Journal of veterinary pharmacology and therapeutics    January 14, 2018   Volume 41, Issue 3 393-401 doi: 10.1111/jvp.12477
Davis JL, Schirmer J, Medlin E.Trazodone is a serotonin receptor antagonist and reuptake inhibitor used extensively as an anxiolytic in human and small animal veterinary medicine. The aims of this study were to determine the pharmacokinetics of oral trazodone in experimental horses and to evaluate the effect of oral trazodone in clinical horses. Six experimental horses were administered trazodone at 7.5 or 10 mg/kg. Plasma concentrations of trazodone and its metabolite (m-CPP) were determined via UPLC-MS/MS. Noncompartmental pharmacokinetic analysis, sedation and ataxia scores were determined. Trazodone was rapidly absorbe...
The UK’s legal position on Animal Sentience.
Equine veterinary journal    January 12, 2018   Volume 50, Issue 2 277 doi: 10.1111/evj.12800
Roger P.No abstract available
Development of a novel equine influenza virus live-attenuated vaccine.
Virology    January 11, 2018   Volume 516 76-85 doi: 10.1016/j.virol.2018.01.005
Rodriguez L, Reedy S, Nogales A, Murcia PR, Chambers TM, Martinez-Sobrido L.H3N8 equine influenza virus (EIV) is an important and significant respiratory pathogen of horses. EIV is enzootic in Europe and North America, mainly due to the suboptimal efficacy of current vaccines. We describe, for the first time, the generation of a temperature sensitive (ts) H3N8 EIV live-attenuated influenza vaccine (LAIV) using reverse-genetics approaches. Our EIV LAIV was attenuated (att) in vivo and able to induce, upon a single intranasal administration, protection against H3N8 EIV wild-type (WT) challenge in both a mouse model and the natural host, the horse. Notably, since our EIV...
Seasonal variation in the prevalence of equine tapeworms using coprological diagnosis during a seven-year period in Denmark.
Veterinary parasitology, regional studies and reports    January 11, 2018   Volume 12 22-25 doi: 10.1016/j.vprsr.2018.01.002
Engell-Sørensen K, Pall A, Damgaard C, Holmstrup M.We investigated the prevalence of equine tapeworms, Anoplocephala spp., in Danish horses during a seven-year period assessed by coprological analysis. The data material included >11,000 observations distributed over the period 2009-2015, and four major geographic regions in Denmark representing sandy soils and clayey moraine soils, respectively. This allowed us to test for possible differences between regions (or soil types) and seasons. For a sub-set of the data (about 1200 observations) age of horses was also known, and it was shown that prevalence was highest in the age group 1-5years and t...
Integrating direct observation and GPS tracking to monitor animal behavior for resource management.
Environmental monitoring and assessment    January 10, 2018   Volume 190, Issue 2 75 doi: 10.1007/s10661-018-6463-3
Walden-Schreiner C, Leung YF, Kuhn T, Newburger T.Monitoring the behavior of pack animals in protected areas informs management about use patterns and the potential associated negative impacts. However, systematic assessments of behavior are uncommon due to methodological and logistical constraints. This study integrated behavior mapping with GPS tracking, and applied behavior change point analysis, as an approach to monitor the behaviors of pack animals during overnight periods. The integrated approach identified multiple grazing patterns (i.e., locally intense grazing, ambulatory grazing) not feasible through a single methodology alone. Mon...