Topic:Anthelmintic Treatment
Anthelmintic treatment involves the use of drugs to control parasitic worm infections in horses. These treatments target various types of internal parasites, such as strongyles, ascarids, and tapeworms, which can affect equine health and performance. The administration of anthelmintics is a common practice in equine management to reduce parasite burdens and minimize the risk of disease transmission. Different classes of anthelmintics, including benzimidazoles, macrocyclic lactones, and pyrantel, are used based on the specific parasitic threats and resistance patterns. This page compiles peer-reviewed research studies and scholarly articles that explore the efficacy, resistance development, and management strategies associated with anthelmintic treatment in horses.
Observations on thiabendazole as an equine anthelmintic. No signs of intoxication were seen in horses dosed with thiabendazole at either 200 mg. or 400 mg. per kg. body-weight. 17 horses were dosed with the drug at a level of 100 mg. per kg. These horses had a mean egg count of 1, 296 e.p.g. before treatment; all were negative for strongyle eggs by the 7th day after treatment. 3 of these horses were killed and few or no strongyles were found; an untreated control animal killed at the same time had many thousands of strongyle worms. Thiabendazole was effective when given either by stomach tube or when mixed in the feed.
Critical tests with polymethylenepiperazine (PMP) against parasites of the horse. In five horses dosed with polymethylenepiperazine at dose levels of 21, 51 or 106 mg. per Ib. body-weight clearance of ascarids was obtained with all dosages. The effect against oxyurids was much less marked and large numbers of immature worms were found at autopsy four days after treatment. About 85% of small strongyles were removed at dosages of 21 mg. per Ib. and above and about 50% of Strongylus vulgaris were removed at dosages of 51 mg. per Ib. and above. The drug was inactive against S. edentatus, Trichostrongylus axei, Habronema muscae and Strongyloides westeri. In another eight horses ...
Field studies with piperazine-carbon disulfide complex against parasites of the horse. In field studies in which 197 sucklings, weanlings and yearlings and mares were treated with Parvex at the dosage rate of 37-5 mg. per Ib. body-weight, both immature and mature ascarids were effectively removed; but this dosage level did not have any apparent action against Strongylus vulgaris or Strongyloides westeri. Low level phenothiazine medication was effective in depressing egg production and inhibiting larval development of strongyles, especially S. vulgaris.