Topic:Biomedical Research
Biomedical research involving horses encompasses the study of biological processes, diseases, and therapeutic interventions in equine species. This field investigates various aspects such as genetics, physiology, pathology, and pharmacology to enhance understanding of equine health and disease mechanisms. Research often focuses on conditions affecting horses, including musculoskeletal disorders, respiratory diseases, and infectious diseases, with the aim of developing effective treatments and preventive measures. Studies also explore the use of horses as models for human diseases, given their physiological similarities in certain areas. This page compiles peer-reviewed research studies and scholarly articles that explore various biomedical topics related to equine health, including disease pathogenesis, diagnostic advancements, and therapeutic innovations.
Electromagnetic blood flowmeters and flow probes: theoretic and practical considerations. Electromagnetic blood flowmeters and flow probes are used to measure blood flow in blood vessels throughout the circulatory system. The principle of this measuring device is based on laws of electromagnetic induction discovered in the 19th century. The instrument has been predominantly used in research, but is presently used in human cardiovascular units to measure blood flow in blood vessels, and in prosthesis in conjection with cardiovascular surgical procedures. Electromagnetic flow equipment provides the most accurate measurement (in vivo) of blood flow available, both for acute and chroni...
Collateral flow resistance and time constants in dog and horse lungs. We studied collateral flow resistance in exsanguinated, excised lower lobes and accessory lobes of dog and horse lungs, respectively. A double lumen catheter obstructed a peripheral airway isolating a segment of the lobe. Oxygen flowed into the segment via a rotameter which measured flow (Vcoll) while the inner catheter recorded segment pressure (Ps). Gas delivered into the segment flowed out via collateral channels. Collateral flow resistance was calculated as (Ps - PL)/Vcoll, where PL = static transpulmonary pressure. Rcoll at PL = 20, 10, and 5 cm H2O averaged 0.24, 1.25, and 2.65 cmH2O.ml-...
Plasmapheresis of horses by extracorporeal circulation of blood. A simple apparatus is described for the collection of plasma from horses while maintaining their blood in extracorporeal circulation. Using this device, nearly 2.5 kg of plasma protein was collected from a horse during a period of 3 weeks without any obvious adverse effect upon the animal. The blood’s packed cell volume showed little variation throughout this period, although its content of plasma protein was found to fall. The normal plasma protein level was almost completely re-established after 3 weeks rest. A horse immunized with tetanus toxoid and subjectcd to repeated cycles of plasmap...
Studies on the equine cardiac electric field. I. Body surface potentials. The paper describes the distribution of cardiac potentials on the body surface of four horses. Potentials were recorded at 200 to 300 equallyspaced sites synchronously with a reference lead; they were measured at 10 msec. instants of time, and were plotted on diagrams. While some evidence of multiple dipolar activity occurred during each part of the cardiac cycle, the majority of potentials arose as if from a single resultant dipole.