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Topic:Clinical Findings

Clinical findings in horses encompass a range of observable signs and symptoms identified during veterinary examinations that contribute to diagnosing and managing equine health conditions. These findings can include physical observations, such as changes in behavior, posture, or gait, as well as physiological measurements like heart rate, respiratory rate, and temperature. Diagnostics may also involve laboratory tests, imaging, and other diagnostic procedures to assess organ function and detect abnormalities. Recognizing and interpreting clinical findings are essential components of veterinary practice, aiding in the identification of diseases, monitoring treatment progress, and guiding therapeutic interventions. This page brings together peer-reviewed research studies and scholarly articles that explore the methodologies, interpretations, and implications of clinical findings in the context of equine health care.
The incidence and severity of intercarpal ligament damage in the equine carpus.
Australian veterinary journal    March 1, 1993   Volume 70, Issue 3 89-91 doi: 10.1111/j.1751-0813.1993.tb03283.x
Kannegieter NJ, Colgan SA.The arthroscopic findings in 104 intercarpal joints in 76 horses were reviewed to determine the incidence and severity of changes in the medial intercarpal ligament. Damage to the intercarpal ligament was observed in 43 joints in 35 horses, ranging from mild fraying of the edges of the ligament to complete disruption of all fibres. This represented an incidence of 41% of joints being affected. In 9 joints examined arthroscopically primarily as a further diagnostic procedure, ligament damage was evident in all cases. In horses undergoing arthroscopic surgery primarily for the treatment of osteo...
Factors influencing the outcome of equine anaesthesia: a review of 1,314 cases.
Equine veterinary journal    March 1, 1993   Volume 25, Issue 2 147-151 doi: 10.1111/j.2042-3306.1993.tb02926.x
Young SS, Taylor PM.Patient data, physiological variables and recovery quality were extracted from 1,314 records of equine anaesthetics covering a 7-year period and analysed retrospectively. Better recovery quality was significantly associated with shorter duration of anaesthesia, longer recovery times, less invasive surgery, a lower pulse rate at induction and higher pulse and respiratory rates during anaesthesia. Nineteen animals suffered serious anaesthetic-related problems (1.4% incidence) and 9 died (0.68% incidence). Clinical treatment of hypotension during anaesthesia significantly reduced the hypotensive ...
Excision of intralaryngeal granulation tissue in 25 horses using a neodymium:YAG laser (1986 to 1991).
Veterinary surgery : VS    March 1, 1993   Volume 22, Issue 2 129-134 doi: 10.1111/j.1532-950x.1993.tb01686.x
Hay WP, Tulleners E.Granulation tissue masses arising from the axial surface of the arytenoid cartilage in 25 horses were excised using a contact neodymium:yttrium aluminum garnet laser. A technique that eliminated the need for general anesthesia or laryngotomy was developed for transen-doscopic removal of the masses in standing horses. Nineteen racehorses made abnormal upper respiratory tract noises or their performance was decreased, whereas six horses not used for racing had a history of stertor (five horses) or epistaxis after nasogastric intubation (one horse). Thoroughbreds were significantly (p = .0126) ov...
Nephrogenic diabetes insipidus in sibling colts.
Journal of veterinary internal medicine    March 1, 1993   Volume 7, Issue 2 68-72 doi: 10.1111/j.1939-1676.1993.tb03172.x
Schott HC, Bayly WM, Reed SM, Brobst DF.Nephrogenic diabetes insipidus was diagnosed in two full sibling Thoroughbred colts. Each colt had a history of excessive urination. Extreme polydipsia (greater than 80 L per day) was documented in both colts. Inability to concentrate urine in response to water deprivation, infusion of hypertonic saline, or exogenous vasopressin administration indicated insensitivity of the collecting duct epithelial cells to vasopressin. A diagnosis of nephrogenic diabetes insipidus was further supported by a normal increase in plasma vasopressin concentration after water deprivation in the one colt in which ...
Clinical evaluation of an infusion of xylazine, guaifenesin and ketamine for maintenance of anaesthesia in horses.
Equine veterinary journal    March 1, 1993   Volume 25, Issue 2 115-119 doi: 10.1111/j.2042-3306.1993.tb02919.x
Young LE, Bartram DH, Diamond MJ, Gregg AS, Jones RS.General anaesthesia was maintained in 40 horses by the continuous intravenous infusion of a mixture of 500 ml 10% guaifenesin solution, 1 g ketamine and 500 mg xylazine. The median duration of infusion was 65 mins (interquartile range 51-95 mins). Anaesthesia was characterised by active palpebral reflexes, variable degrees of nystagmus and occasional swallowing. Swallowing was considered to be undesirable in horses undergoing laryngeal surgery, but the infusion produced satisfactory conditions for all other surgical procedures performed. Arterial blood pressure was well maintained in all cases...
Recognition of Pneumocystis carinii in foals with respiratory distress.
Equine veterinary journal    March 1, 1993   Volume 25, Issue 2 103-108 doi: 10.1111/j.2042-3306.1993.tb02917.x
Ainsworth DM, Weldon AD, Beck KA, Rowland PH.Five 3-month-old foals presenting with fever and respiratory disease were found to have pulmonary abscesses with patchy to diffuse alveolar and interstitial pneumonia on post-mortem examination. All affected foals had evidence of Rhodococcus equi infection and had few to abundant Pneumocystis carinii cysts in the sections of affected lung. Of the 5 foals examined radiographically, 3 had a distinct reticulonodular (miliary) pattern which may aid in the ante-mortem diagnosis of P. carinii pneumonia (PCP). Leukocyte counts of foals with PCP were significantly greater than in the control group of ...
Summer pasture-associated obstructive pulmonary disease in horses: 21 cases (1983-1991).
Journal of the American Veterinary Medical Association    March 1, 1993   Volume 202, Issue 5 779-782 
Seahorn TL, Beadle RE.Medical records of 21 horses with summer pasture-associated obstructive pulmonary disease were reviewed, and history, signalment, clinical signs, radiographic signs, clinicopathologic data, and therapeutic response were determined. Most affected horses were used as pleasure horses, and for the most part, remained at pasture when not in use. The mean age (+/- SD) was 13.7 +/- 3.6 years. Clinical signs included intermittent nasal discharge, cough, tachypnea, labored expiratory effort, and crackles and wheezes on auscultation. Radiography frequently revealed interstitial patterns in the lung fiel...
The contribution of complement to opsonic activity in the uterine secretions of mares free of endometritis.
Theriogenology    March 1, 1993   Volume 39, Issue 3 601-609 doi: 10.1016/0093-691x(93)90247-3
Hakansson A, Albihn A, Magnusson U.The aim of the present study was to investigate if complement contributes to opsonic activity in the uterine secretions of mares with normal reproductive functions. Five mares with a mean age of 9 years were used in the study. The mares were considered to be free of endometritis based upon clinical history, palpation per rectum and ultrasonogaraphy of the genital tract, videoendoscopic inspection of the uterus, electronmicroscopy of endometrial biopsies, and bacteriological and cytological examination of swabs from the endometrium. The hormonal status of the mares was also determined. Uterine ...
Pathological lesions associated with Anoplocephala perfoliata at the ileo-caecal junction of horses.
The Veterinary record    February 20, 1993   Volume 132, Issue 8 179-182 doi: 10.1136/vr.132.8.179
Pearson GR, Davies LW, White AL, O'Brien JK.The intestinal tracts of 20 horses, killed at a local abattoir and of unknown age, sex and previous clinical history were examined for the presence of Anoplocephala perfoliata attached to the ileo-caecal junction. Four horses had no tape-worms, nine had one to 20 tapeworms attached to the mucosa and seven had more than 100 attached to the mucosa. The histological changes of thickening, ulceration and eosinophil infiltration of the mucosa at the ileo-caecal junction were more severe when more than 100 parasites were present.
Use of esophagoscopy in the diagnosis of esophageal squamous cell carcinoma in a horse.
Journal of the American Veterinary Medical Association    February 15, 1993   Volume 202, Issue 4 617-618 
Campbell-Beggs CL, Kiper ML, MacAllister C, Henry G, Roszel JF.Esophagoscopy allowed visualization and biopsy of a lesion within a diverticulum of the esophagus in an adult horse. Although the biopsy specimen obtained was small, diagnosis of squamous cell carcinoma was possible from histologic examination of the esophageal tissue sample retrieved by use of endoscopy.
Hoary alyssum (Berteroa incana) toxicity in a herd of broodmare horses.
Veterinary and human toxicology    February 1, 1993   Volume 35, Issue 1 39-40 
Hovda LR, Rose ML.A herd of pregnant horses exposed to hoary alyssum through ingested hay developed acute and severe gastrointestinal toxicity accompanied by intravascular hemolysis. Postmortem lesions were consistent with these signs. Three horses had late-term abortions.
Nervous system injuries in horseback-riding accidents.
The Journal of trauma    February 1, 1993   Volume 34, Issue 2 227-232 doi: 10.1097/00005373-199302000-00008
Hamilton MG, Tranmer BI.A review of 156 horseback-riding accidents that occurred in southern Alberta over a 6-year period and resulted in nervous system trauma, including 11 deaths, is presented. The majority (81%) of accidents occurred during recreational activity and 81% were associated with falling or being thrown from a horse. Head injury occurred in 92% of patients and accounted for all of the 11 deaths. Spinal injury occurred in 13% of the patients and was associated with head injury in 40%. One peripheral nerve injury was identified. Helmets were used by only two victims. The 11 deaths that occurred as a conse...
Bilateral optic disc colobomas and microphthalmos in a thoroughbred horse.
The Veterinary record    January 30, 1993   Volume 132, Issue 5 101-103 doi: 10.1136/vr.132.5.101
Williams DL, Barnett KC.A thoroughbred colt had bilateral but unequal microphthalmos together with microcornea, abnormalities of the iris and lens and posterior segment colobomas. The case is compared with other reports of microphthalmos and coloboma in horses.
Self-mutilative behavior in horses.
Journal of the American Veterinary Medical Association    January 15, 1993   Volume 202, Issue 2 179-180 
McClure SR, Chaffin MK.No abstract available
Intratumoral chemotherapy with cisplatin in oily emulsion in horses.
Journal of the American Veterinary Medical Association    January 15, 1993   Volume 202, Issue 2 261-267 
Théon AP, Pascoe JR, Carlson GP, Krag DN.Twenty horses with 30 lesions were studied to evaluate the effects of intratumoral chemotherapy with cisplatin in sesame oil on equine sarcoids (n = 19), squamous cell carcinomas (n = 7), and squamous cell papillomas (n = 4). Treatment consisted of 4 sessions of intratumoral cisplatin chemotherapy at 2-week intervals. A controlled-release formulation of cisplatin in sesame oil was used to limit drug egress from the injection site. Mean dosage per session was 0.97 (+/- 0.17, SEM) mg of cisplatin/cm3 of tumor tissue treated for tumor volumes ranging from 10 to 20 cm3. Dosage tended to be slightl...
Qualitative and morphometric radiographic findings in the distal phalanx and digital soft tissues of sound thoroughbred racehorses.
American journal of veterinary research    January 1, 1993   Volume 54, Issue 1 38-51 
Linford RL, O'Brien TR, Trout DR.Lameness examinations and radiography of the distal phalanx and associated soft-tissue structures of the front feet of 103 Thoroughbred racehorses, 4 to 9 years old, were performed to determine normal radiographic appearance and morphometry. Of 103 horses examined, 41 were used in the study that were without clinical signs of foot problems or lameness, had raced at least twice prior to radiography, and had raced at least twice more in the 6 months after radiography. Lateromedial and dorsoproximal-palmarodistal radiographic views of each front distal phalanx were used to measure 28 bone and sof...
Fracture of the caudal medial femoral condyle in a horse.
Equine veterinary journal    January 1, 1993   Volume 25, Issue 1 75-77 doi: 10.1111/j.2042-3306.1993.tb02907.x
Dabareiner RM, Sullins KE.No abstract available
Segmental ischemic necrosis of the small intestine in two postparturient mares.
Journal of the American Veterinary Medical Association    January 1, 1993   Volume 202, Issue 1 101-103 
Zamos DT, Ford TS, Cohen ND, Crossland LE.Two mares developed segmental ischemic necrosis of the small intestine after parturition. In one mare, the mesentery of the small intestine apparently tore during parturition, after which necrosis developed in a 52-cm segment of the distal portion of jejunum. In the other mare, a 52-cm segment of the proximal portion of ileum tore during parturition. Three weeks later, a 40-cm segment of the distal portion of jejunum became incarcerated in the mesenteric rent and twisted 360 degrees on its mesentery. Both mares recovered after resection of affected intestine and are functioning as broodmares.
Scleral mastocytosis in a horse.
Equine veterinary journal    January 1, 1993   Volume 25, Issue 1 79-80 doi: 10.1111/j.2042-3306.1993.tb02909.x
Ward DA, Lakritz J, Bauer RW.No abstract available
[Doppler ultrasound measurement of the cardiac volume of the horse].
Tierarztliche Praxis. Supplement    January 1, 1993   31 
Stadler P, Kinkel N, Deegen E.No abstract available
[Echocardiographic findings in auricular fibrillation of the horse].
Tierarztliche Praxis. Supplement    January 1, 1993   30 
Stadler P, Deegen E.No abstract available
Poliomyelomalacia and ganglioneuritis in a horse with paralytic rabies. O'Toole D, Mills K, Ellis J, Welch V, Fillerup M.No abstract available
A retrospective evaluation of laminitis in horses.
Equine veterinary journal    January 1, 1993   Volume 25, Issue 1 61-64 doi: 10.1111/j.2042-3306.1993.tb02903.x
Hunt RJ.Case records of 202 horses treated for laminitis were reviewed with the intent of determining the long-term outcome and correlating this with digital radiographic findings and with the degree of pain associated with the laminitis. At long-term follow-up 57 horses had returned to athletic soundness (Group 1), 20 horses were intermittently lame (Group 2), 19 horses had permanent severe lameness (Group 3), 97 were dead (Group 4), and 9 were lost to follow up. Using simple regression analysis, functional outcome did not correlate with the degree of rotation (R2 = 0.004) or the presence of distal d...
An investigation of injection techniques for local analgesia of the equine distal tarsus and proximal metatarsus.
Equine veterinary journal    January 1, 1993   Volume 25, Issue 1 30-35 doi: 10.1111/j.2042-3306.1993.tb02897.x
Dyson SJ, Romero JM.A positive radiographic contrast agent was injected into the tarsometatarsal (TMT) joints of both hindlimbs of 10 horses. Lateromedial radiographic views were obtained at 5, 15 and 30 mins after injection. Injection was successful in 19 of 20 limbs. Communication between the centrodistal (CD) and TMT joints was identified in 7 limbs (35%). Contrast agent extended around the tendons of tibialis cranialis (TC) and fibularis tertius (FT) in 18 limbs, and in 7 limbs some contrast entered the tarsal sheath. Slight to moderate plantar and/or distal extension of contrast agent was identified in 13 li...
Partial arytenoidectomy in the horse using an extralaryngeal approach.
Veterinary surgery : VS    January 1, 1993   Volume 22, Issue 1 50-56 doi: 10.1111/j.1532-950x.1993.tb00368.x
Hay WP, Tulleners EP, Ducharme NG.An extralaryngeal approach to partial arytenoidectomy in the horse was developed by in vitro experiments on isolated larynges and then on intact equine cadavers. The goals of the approach were to preserve the laryngeal mucosa, eliminate the need for a laryngotomy or tracheotomy, and minimize postoperative complications. The new approach was evaluated in seven horses with normal upper respiratory tracts. Left laryngeal hemiplegia was surgically created, and, after a 30-day convalescence, left partial arytenoidectomy was performed using an extralaryngeal approach. The left-to-right hemilaryngeal...
Naturally occurring selenosis in Wyoming. Raisbeck MF, Dahl ER, Sanchez DA, Belden EL, O'Toole D.A review of Wyoming State Veterinary Laboratory records for 1947-1987 revealed no substantiated cases of naturally occurring selenosis. However, older reports attributed thousands of animal deaths to selenium each year in this area. Beginning in August 1988, cases of suspected selenosis and selenium deficiency were solicited from veterinarians and producers by announcements in various statewide livestock publications. As of August 1991, 4 cases (all horses) of naturally occurring selenosis have been confirmed. Clinical signs were most often referable to epithelial damage, e.g., hoof lesions an...
Plasma potassium measurement with a new reagent carrier (Reflotron): comparison with ion-selective electrode results.
Research in veterinary science    January 1, 1993   Volume 54, Issue 1 127-129 doi: 10.1016/0034-5288(93)90022-8
Braun JP, Carstensen CA.Potassium concentrations were measured in the plasma of 336 animals with a new reagent carrier (Reflotron; Boehringer Mannheim) K+ and with an ion-specific electrode system: results were highly correlated (r = 0.991; y = 0.993 x + 0.02) and day-to-day coefficient of variation of the new reagent measurements was lower than 2.5 per cent. This system offers a good alternative to the ion-selective electrode system for plasma potassium measurement in veterinary practice.
Quantitative determination of equine alkaline phosphatase isoenzymes in foal and adult serum.
Journal of veterinary internal medicine    January 1, 1993   Volume 7, Issue 1 20-24 doi: 10.1111/j.1939-1676.1993.tb03164.x
Hank AM, Hoffmann WE, Sanecki RK, Schaeffer DJ, Dorner JL.Automated and semiautomated assays were developed and validated for the determination of equine alkaline phosphatase isoenzymes including intestinal (IALP), bone (BALP), and liver (LALP). The addition of levamisole selectively inhibited more than 97% of LALP while inhibiting only 55% of IALP. Because these percentages were highly reproducible in an automated system, the IALP activity could be calculated in a sample. Bone alkaline phosphatase isoenzyme was selectively precipitated by adding an equal volume of wheat germ agglutinin (5 mg/mL), incubating for 30 minutes at 37 degrees C, and centri...
Mal seco, a grass sickness-like syndrome of horses in Argentina.
Veterinary research communications    January 1, 1993   Volume 17, Issue 6 449-457 doi: 10.1007/BF01839212
Uzal FA, Robles CA.Mal seco is a grass sickness-like syndrome of horses which has mainly been observed in Patagonia, Argentina, although some reports indicate that the disease may exist in other Argentinian provinces and in the south of Chile. The aetiology of mal seco remains unknown but the disease seems to be restricted to animals grazing on natural pastures and not receiving supplementary feeding. Mal seco is clinically characterized by total or partial bowel stasis and the main findings at post-mortem examination are almost exclusively restricted to the bowel. The most striking histopathological changes fou...
Motor neuron degeneration in a horse.
Journal of the American Veterinary Medical Association    January 1, 1993   Volume 202, Issue 1 86-88 
Step DL, Cummings JF, de Lahunta A, Valentine BA, Summers BA, Rowland PH, Mohammed HO, Eckerlin RH, Rebhun WC.A 9-year-old Quarter Horse mare was examined because of progressive weight loss, weakness, muscle atrophy and tremors, and behavioral change. Selenium and glutathione peroxidase assays, blood lead analysis, erythrocyte transketolase analysis, pseudorabies and Borrelia burgdorferi serology, electromyography, and CSF analysis were performed. Motor neuron degeneration was diagnosed by microscopic examination of neural tissues. The cause of the disease was not substantiated, but several possibilities were excluded via diagnostic testing. Diagnosis of motor neuron degeneration in horses may be made...