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Topic:Clinical Findings

Clinical findings in horses encompass a range of observable signs and symptoms identified during veterinary examinations that contribute to diagnosing and managing equine health conditions. These findings can include physical observations, such as changes in behavior, posture, or gait, as well as physiological measurements like heart rate, respiratory rate, and temperature. Diagnostics may also involve laboratory tests, imaging, and other diagnostic procedures to assess organ function and detect abnormalities. Recognizing and interpreting clinical findings are essential components of veterinary practice, aiding in the identification of diseases, monitoring treatment progress, and guiding therapeutic interventions. This page brings together peer-reviewed research studies and scholarly articles that explore the methodologies, interpretations, and implications of clinical findings in the context of equine health care.
Clinical, hematologic, hemostatic, and serum biochemical findings related to survival in Arabian horses with colic.
Veterinary clinical pathology    September 17, 2019   Volume 48, Issue 3 441-448 doi: 10.1111/vcp.12779
Nikvand AA, Jalali SM, Ghadrdan Mashhadi A, Razi Jalali M, Hassanpour Amirabadi S.The efficacy of clinical examinations, and hematologic, hemostatic, and serum biochemical assessments to determine appropriate early medical or surgical therapy in Arabian horses with colic have not been well-described. Objective: We aimed to evaluate clinical and hematologic findings, coagulation-fibrinolytic parameters, and organ dysfunction markers in association with survival in horses with colic. Methods: Seventeen Arabian horses with colic and ten healthy horses were enrolled. After clinical examinations, including heart rates (HRs), capillary refill times (CRTs), abdominal sounds, recta...
Ex Vivo Comparison of the Accuracy of a Clamped with a Hand-Held Drill Guide for Drilling Distal Third Metacarpals and Metatarsals in Equids.
Veterinary and comparative orthopaedics and traumatology : V.C.O.T    September 9, 2019   Volume 33, Issue 1 15-21 doi: 10.1055/s-0039-1694972
James OA, Elce Y, Cillán-Garcia E, Reardon RJM. The aim of this study was to determine whether a clamped drill guide can be used effectively to drill across equine distal third metacarpals and metatarsals and to compare accuracy and speed of a drilling with a hand-held drill guide. Methods:  Eighty equine cadaver limbs were divided between four surgeons with varying experience. The limbs were randomly allocated to clamped or hand-held drill guides and placed in a stand in an upright/standing position on a metal table. Drilling times from cis- to trans cortices were measured. Post-drilling computed tomography images were used to assess ...
Mare and foal survival following emergency Caesarean section at a UK hospital.
Equine veterinary journal    September 3, 2019   Volume 51 Suppl 53 6 doi: 10.1111/evj.02_13152
No abstract available
The influence of tenoscopic approaches on radiocarpal joint perforation during carpal sheath tenoscopy in horses.
Veterinary surgery : VS    August 29, 2019   Volume 49, Issue 2 274-280 doi: 10.1111/vsu.13316
Skov Hansen S, Tóth T.To report the frequency of radiocarpal joint (RCJ) perforation during two proximolateral carpal sheath (CS) approaches and to investigate whether the presence or absence of a natural communication between the RCJ and CS. Methods: Experimental, randomized, controlled study. Methods: Twelve adult horses and 12 cadaver front limbs. Methods: Proximolateral CS tenoscopy was performed on both carpi of 12 horses under general anaesthesia. Limbs were randomly assigned into two groups. In group 1, the instrument portal was centered at the level of the distal radial physeal remnant (PR). In group 2, the...
Evaluation of the effects of commonly used α2-adrenergic receptor agonists alone and in combination with butorphanol tartrate on objective measurements of lameness in horses.
American journal of veterinary research    August 27, 2019   Volume 80, Issue 9 868-877 doi: 10.2460/ajvr.80.9.868
Moorman VJ, Bass L, King MR.To determine the effects of 3 α2-adrenergic receptor agonists (α2-ARAs), alone or in combination with butorphanol tartrate, on objective measurements of lameness in horses. Methods: 17 adult polo horses with naturally occurring forelimb or hind limb lameness (or both). Methods: In a crossover design, each horse received each protocol (saline [0.09% NaCl] solution [2 mL, IV] or xylazine hydrochloride [0.33 mg/kg, IV], detomidine hydrochloride [0.007 mg/kg, IV], or romifidine hydrochloride [0.033 mg/kg, IV] alone or in combination with butorphanol [0.007 mg/kg, IV]) in random order, with a was...
Clinical findings and management of six horses with subtendinous bursitis of the long digital extensor tendon in the hind limb fetlock.
Veterinary surgery : VS    August 24, 2019   Volume 48, Issue 8 1514-1519 doi: 10.1111/vsu.13315
Iglesias-García M, Roquet I, Jiménez J, Martín-Cuervo M, Fuentes-Romero B, Ezquerra-Calvo LJ.To describe the history, clinical signs, and management of six horses in which subtendinous bursitis of the long digital extensor tendon (LDET) in the hind limb fetlock had been diagnosed. Methods: Retrospective case series. Methods: Six privately owned horses. Methods: The medical records of horses presented at the hospital with similar sypmtoms were evaluated and collected. Finally 6 horses met the inclusion criteria and the relevant data were compiled and analysed. In three of the six cases a surgical treatment was carried out. Results: All horses had similar clinical signs, mainly distenti...
Precision and accuracy of a point-of-care glucometer in horses and the effects of sample type.
Veterinary journal (London, England : 1997)    August 23, 2019   Volume 252 105359 doi: 10.1016/j.tvjl.2019.105359
Rendle DI, Armstrong SK, Heller J, Hughes KJ.Point-of-care glucometry is used commonly in clinical and research settings; however, accuracy and precision of this method are concerns. The objectives of this study were to determine the accuracy of glucometry in adult horses and the precision of duplicate measurements. Blood samples were collected from 62 horses into one plain syringe, one EDTA tube and three fluoride oxalate (FO) tubes. Immediately after collection, glucose concentrations in whole blood were determined, in duplicate, by glucometry from the syringe (plain whole blood [WB] group), EDTA tube (EDTA group) and one FO tube (FO g...
Prevalence of acute kidney injury in a population of hospitalized horses.
Journal of veterinary internal medicine    August 22, 2019   Volume 33, Issue 5 2294-2301 doi: 10.1111/jvim.15569
Savage VL, Marr CM, Bailey M, Smith S.Hospital-acquired acute kidney injury (AKI) in humans and dogs increases morbidity and nonsurvival. Azotemia at presentation has been associated with a poor outcome in horses; however, prevalence and consequences of hospital-acquired AKI are unreported. Objective: To evaluate the prevalence of AKI in hospitalized horses, risk factors associated with AKI, and the effect of AKI on short-term survival. We hypothesized that the prevalence of AKI in horses is similar to that reported in other domestic mammalian species and would be associated with nonsurvival. Methods: Adult horses hospitalized for...
[Is summer eczema predictable in imported Icelandic horses?].
Tierarztliche Praxis. Ausgabe G, Grosstiere/Nutztiere    August 21, 2019   Volume 47, Issue 4 271 doi: 10.1055/a-0975-5197
Hampe M.Torsteinsdottir S, Scheidegger S, Baselgia S et al. A prospective study on insect bite hypersensitivity in horses exported from Iceland into Switzerland. Acta Vet Scand 2018; 60: 69 BEIM SOMMEREKZEM HANDELT ES SICH UM EINE IGE-VERMITTELTE DERMATITIS INFOLGE EINER ALLERGISCHEN REAKTION AUF DEN SPEICHEL STECHENDER INSEKTEN (Z. B. CULICOIDES SPP.). BIS ZU 50 % DER AUS ISLAND NACH KONTINENTALEUROPA IMPORTIERTEN TIERE ERKRANKEN, DAGEGEN NUR 3–10 % DER AUF DEM FESTLAND GEBORENEN ISLäNDER. IN ISLAND GIBT ES DIE ERKRANKUNG NICHT, DA DIE VERURSACHENDEN GNITZEN DORT NICHT VORKOMMEN. HAT EINE SENSIBIL...
Clinical Effects of the Extract of the Seeds of the Indian Celery-Apium Graveolens-In Horses Affected by Chronic Osteoarthritis.
Animals : an open access journal from MDPI    August 20, 2019   Volume 9, Issue 8 doi: 10.3390/ani9080585
Battaglia B, Angelone M, Vera E, Basini G, Bussolati S, Paci M, Bue MD, Aldigeri R, Grolli S, Quintavalla F, Ramoni R.The extract of the seeds from Indian celery, Apium greaveolens (CSE), tested in experimental animals (rodents), and in humans affected by chronic osteoarthritic diseases, exhibits anti-inflammatory effects that can be compared, to some degree, to those of non-steroid anti-inflammatory drugs (NSAID). In view of a potential use of CSE in the equine species, it was tested on horses affected by chronic articular pathologies. The trial was performed on 20 horses divided into three different groups, orally treated with 0 (controls), 7.0 or 30 g of CSE BID. Basic orthopedic examinations were conducte...
Radiographic and arthroscopic features of third carpal bone slab fractures and their impact on racing performance following arthroscopic repair in a population of racing Thoroughbreds in the UK.
Equine veterinary journal    August 19, 2019   Volume 52, Issue 2 213-218 doi: 10.1111/evj.13155
Baldwin CM, Smith MRW, Allen S, Wright IM.Slab fractures of the third carpal bone (C3) are a common injury of Thoroughbred racehorses. Results of arthroscopically guided repair have not been reported since the initial description of the technique in 1986. Additionally, fracture details and racing outcomes in a population of Thoroughbreds racing under UK jurisdiction have not previously been described. Objective: To report the frequency distribution of C3 slab fractures and to determine the impact on racing performance following arthroscopically guided repair in a population of Thoroughbred racehorses. Methods: Retrospective case serie...
Retrospective evaluation of clinical use of cis-atracurium in horses.
PloS one    August 15, 2019   Volume 14, Issue 8 e0221196 doi: 10.1371/journal.pone.0221196
Tutunaru A, Dupont J, Gougnard A, Ida K, Serteyn D, Sandersen C.To the authors' knowledge, there are no reports describing the use of cis-atracurium in the horse. To describe the onset time and the duration of the neuromuscular blockade (NMB) of three different doses of cis-atracurium in horses and to determine the appropriate dose needed maintain a NMB. Retrospective study. Horses which received cis-atracurium as part of a balanced anaesthetic protocol at the Equine Teaching Hospital of the University of Liège between March 2014 and June 2017 were included in this study. A train-of-four (TOF) stimulation pattern was used to assess the NMB. The cis-atracu...
Use of perioperative variables to determine the requirement for repeat celiotomy in horses with postoperative reflux after small intestinal surgery.
Veterinary surgery : VS    August 12, 2019   Volume 48, Issue 7 1204-1210 doi: 10.1111/vsu.13306
Jacobs CC, Stefanovski D, Southwood LL.To determine whether perioperative variables can be used to differentiate a medical vs a surgical reason for postoperative reflux (POR) after small intestinal (SI) surgery in horses. Methods: Retrospective study. Methods: Horses >1 year of age that recovered from SI surgery and had POR. Methods: Medical records of horses that underwent SI surgery and developed POR from 2009-2015 were reviewed. Surgical reasons for POR were defined as an anastomosis complication, mechanical obstruction, or nonviable intestine identified at repeat celiotomy/necropsy. A medical reason for POR was presumed wh...
Partial resection of bilateral ulnar remnants for treatment of carpus valgus in a 3-week-old Hanoverian foal.
The Canadian veterinary journal = La revue veterinaire canadienne    August 9, 2019   Volume 60, Issue 8 864-868 
Dubuc J, Da Silveira EA.A 3-week old Hanoverian foal was presented with bilateral moderate to severe carpal valgus. The deviations were 10 and 14 degrees, respectively for the left and right carpi and orthogonal radiographs of both front limbs highlighted bilateral persistent ulnar remnants. A partial resection of the ulnar remnants and periosteal transection on the disto-lateral aspect of the radius were performed bilaterally under general anesthesia. The valgus deviations began to improve within the first month and the limbs were almost straight (2 degrees for the left and right carpi) 5 1/2 months after surgery. T...
Effects of acellular equine amniotic allografts on the healing of experimentally induced full-thickness distal limb wounds in horses.
Veterinary surgery : VS    August 6, 2019   Volume 48, Issue 8 1416-1428 doi: 10.1111/vsu.13304
Fowler AW, Gilbertie JM, Watson VE, Prange T, Osborne JA, Schnabel LV.To characterize the growth factors contained in equine amniotic membrane allograft (eAM; StemWrap scaffold and StemWrap+ injection) and to evaluate the effect of eAM on equine distal limb wound healing. Methods: Prospective experimental controlled study. Methods: Eight adult horses. Methods: Transforming growth factor (TGF)-β1, vascular endothelial growth factor (VEGF), epidermal growth factor, platelet-derived growth factor-BB, and prostaglandin E2 (PGE2 ) concentrations in StemWrap+ were assessed with enzyme-linked immunosorbent assay. Two full-thickness 6.25-cm2 skin wounds were created on...
Clinical insights: Equine anaesthesia and analgesia.
Equine veterinary journal    August 3, 2019   Volume 51, Issue 5 563-564 doi: 10.1111/evj.13147
Southwood L.No abstract available
Letter to the Editor: Prospective, randomised clinical trial of four different presurgical hand antiseptic techniques in equine surgery.
Equine veterinary journal    August 3, 2019   Volume 51, Issue 5 705 doi: 10.1111/evj.13139
Kampf G, Verwilghen D.No abstract available
Highlights of recent clinically relevant papers.
Equine veterinary education    August 1, 2019   Volume 31, Issue 9 450-451 doi: 10.1111/eve.13155
Wright S.No abstract available
Equine infectious keratitis in Finland: Associated microbial isolates and susceptibility profiles.
Veterinary ophthalmology    July 31, 2019   Volume 23, Issue 1 148-159 doi: 10.1111/vop.12701
Mustikka MP, Grönthal TSC, Pietilä EM.To retrospectively describe laboratory findings, treatment, and outcome associated with equine infectious keratitis in Finland. Unassigned: Medical records of horses diagnosed with infectious keratitis in University of Helsinki Equine Hospital from January 2007 to June 2018 were reviewed. Results: Forty-seven cases were included. Keratomycosis was diagnosed in 27 eyes and bacterial keratitis in 20 eyes. Aspergillus flavus was the most frequent fungal isolate (9/17, 53%), followed by Cylindrocarpon sp. (3/17, 18%) and Aspergillus fumigatus (2/17, 12%). Susceptibility was tested for 10/11 Asperg...
Equine cheek tooth extraction: Comparison of outcomes for five extraction methods.
Equine veterinary journal    July 30, 2019   Volume 52, Issue 2 181-186 doi: 10.1111/evj.13150
Caramello V, Zarucco L, Foster D, Boston R, Stefanovski D, Orsini JA.Post-operative complications are reported for all methods of equine cheek tooth extraction but not all methods carry the same risks. An outcome comparison for commonly used methods is needed so that clinicians can make informed treatment decisions. Objective: We conducted a side-by-side comparison of five cheek tooth extraction methods, comparing types and incidence of complications among oral extraction, tooth repulsion (three surgical approaches) and lateral buccotomy techniques. Methods: Retrospective clinical study using hospital medical records. Methods: Medical records of all horses unde...
Equine odontogenic tumors: Clinical presentation, CT findings, and outcome in 11 horses. Morgan RE, Fiske-Jackson AR, Hellige M, Gerhauser I, Wohlsein P, Biggi M.Odontogenic tumors present as locally invasive, slow growing, firm swellings on the face. They are rare in all species and are characterized histologically by the degree of differentiation and dental tissue of origin. Radiographic appearance is not pathognomonic for these lesions. Computed tomographic (CT) examination allows exact determination of tumor extension and aggressiveness. The objectives of this retrospective, case series study were to describe the clinical presentation, CT characteristics, and outcome in horses with histologically confirmed odontogenic tumors, and to identify imagin...
Ocular leptospiral infection leads to ciliary induction and local AA-amyloidosis in horses. Linke RP, Brandes K, Cielewicz MB, Gerhards H, Wollanke B.No abstract available
Lochial and endometrial cytological changes during the first 10 days post-partum with special reference to the nature of foaling and puerperium in equine.
Theriogenology    July 22, 2019   Volume 139 43-48 doi: 10.1016/j.theriogenology.2019.07.023
Krohn J, Eilenberg RD, Gajewski Z, Failing K, Wehrend A.During the puerperium, pregnancy-associated changes of the uterus need to be reversed. The duration of this process is of importance in terms of breeding efficiency and thus monitoring and treatment of the disturbed puerperium are essential. Aim of this investigation was to identify changes over time in the cellular composition of samples from endometrium and lochia in 120 mares with different obstetrical and puerperal history. In regular examinations up to 10 days post-partum the uterine involution was assessed by transrectal palpation and ultrasound. The vagina and cervix were examined using...
A study of residual lesions in horses that recovered from clinical signs of chronic equine dysautonomia.
Journal of veterinary internal medicine    July 22, 2019   Volume 33, Issue 5 2302-2311 doi: 10.1111/jvim.15567
Milne EM, Pirie RS, Hahn CN, Del-Pozo J, Drummond D, Moss S, McGorum BC.Equine dysautonomia (ED) causes degeneration and loss of autonomic neurons. Approximately 50% of chronic cases recover, but it is unclear how they survive neuronal loss. Objective: To assess lesions, autonomic neuron numbers, interstitial cells of Cajal (ICC), and neurodegeneration in recovered cases. Methods: Thirteen cases (group ED), euthanized 10.3 ± 5.2 (1-16) years from diagnosis and 6 age-matched controls (group C). Methods: Prospective, case control; routine post mortem examination, neuron counts in peripheral and enteric ganglia and immunohistochemical assessment of neural networ...
Agreement among equine veterinarians and between equine veterinarians and inertial sensor system during clinical examination of hindlimb lameness in horses.
Equine veterinary journal    July 21, 2019   Volume 52, Issue 2 326-331 doi: 10.1111/evj.13144
Leelamankong P, Estrada R, Mählmann K, Rungsri P, Lischer C.Hindlimb lameness evaluation is known to be challenging. Experience is essential for the ability of equine veterinarians to detect lameness. Nevertheless, even an experienced veterinarian is still subject to bias. Objective lameness detecting methods have been established to aid veterinarians. Objective: 1) To estimate the effect of experience on the interobserver agreement and the agreement between a body-mounted inertial sensor system (BMISS) and veterinarians on detecting hindlimb lameness, and 2) to estimate the agreement between the BMISS and highly experienced veterinarians on change in ...
Acute fatal poisoning by spontaneous ingestion of Enterolobium contortisiliquum (Mimosidae) pods in horses.
Toxicon : official journal of the International Society on Toxinology    July 19, 2019   Volume 168 122-125 doi: 10.1016/j.toxicon.2019.07.006
Machado M, Miguel MP, Terra JP, Ferreira JA, Riet-Correa F, de Castro MB.An outbreak of acute poisoning of horses by Enterolobium contortisiliquum pods is reported in the state of Goiás, Brazil. Three horses presented apathy, hyporexia, prostration, jaundice, recumbency and died in 24-48 hours. The main pathological findings were a yellowish liver with an enhanced lobular pattern, multifocal hepatic necrosis mostly in the midzones of lobules and sometimes with a random distribution across the hepatic lobes and swelling of hepatocytes. E. contortisiliquum trees has a wide distribution in South America and cases of poisoning have not been reported in horses.
Clinical efficacy of clodronic acid in horses diagnosed with navicular syndrome: A field study using objective and subjective lameness evaluation.
Research in veterinary science    July 19, 2019   Volume 125 298-304 doi: 10.1016/j.rvsc.2019.07.018
Argüelles D, Saitua A, de Medina AS, Muñoz JA, Muñoz A.Navicular syndrome, a common cause of equine forelimb lameness, is associated with pathological changes in the navicular bone. Consequently, administration of bisphosphonates (BPs) has been advocated in order to modify the rate of bone turnover. The present study aimed to assess the clinical efficacy of intramuscularly administered clodronic acid for the treatment of 11 horses with clinical and radiographic findings compatible with navicular syndrome. Magnetic resonance imaging was performed in 5 of the 11 horses. The animals were treated with an intramuscular dose of clodronic acid of 765 m...
Fetal Death Associated With Premature Mammary Gland Development and Lactation in a Mare Treated With Weekly Injections of Long-Acting Progesterone.
Journal of equine veterinary science    July 18, 2019   Volume 81 102783 doi: 10.1016/j.jevs.2019.07.004
McAfoos JL, Ellerbrock RE, Canisso IF.A 14-year-old, 530-kg, multiparous, pregnant Quarter Horse mare was referred for evaluation of premature mammary gland development and lactation. The mare was in the seventh month of gestation. The mare had a history of subfertility and was receiving weekly injections of long-acting progesterone, prescribed by the referring veterinarian. The last dose had been administered four days before presentation. Upon presentation, the mare had vital signs within normal limits, a moderately developed, nonpainful udder with galactorrhea, and no vulvar discharge. Transrectal palpation revealed a well-tone...
Ultrasonographic findings post laryngoplasty in the horse. Miller S, Carstens A.Laryngoplasty is commonly used to treat laryngeal hemiplegia in Thoroughbred racehorses. Evaluation of the success of the laryngoplasty is traditionally determined using endoscopy. Laryngeal ultrasonography and normal ultrasonographic appearance have been reported in the standing horse, but post-laryngoplasty and ventriculectomy ultrasonographic evaluation has limited literature coverage. A prospective case series of 10 Thoroughbred racehorses with left laryngeal hemiplegia was examined ultrasonographically and endoscopically prior to 3-10 days, 30-50 days, and 6-12 months after laryngoplasty ...
Restoration of arterial oxygen tension in horses recovering from general anaesthesia.
Equine veterinary journal    July 16, 2019   Volume 52, Issue 2 187-193 doi: 10.1111/evj.13142
Bardell D, Mosing M, Cripps PJ.Arterial hypoxaemia is common in anaesthetised horses, but little information exists regarding restoration of arterial oxygen tension (PaO ) during recovery from anaesthesia, or if intra-operative management factors exert any longer-term effect. Objective: To evaluate PaO in horses recovering from general anaesthesia up to 1 h after resuming standing. Methods: Prospective observational clinical cohort study. Methods: Systemically healthy adult horses undergoing inhalational general anaesthesia for elective surgical procedures were studied. Arterial blood samples were obtained anaerobically pr...
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