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Topic:Clinical Findings

Clinical findings in horses encompass a range of observable signs and symptoms identified during veterinary examinations that contribute to diagnosing and managing equine health conditions. These findings can include physical observations, such as changes in behavior, posture, or gait, as well as physiological measurements like heart rate, respiratory rate, and temperature. Diagnostics may also involve laboratory tests, imaging, and other diagnostic procedures to assess organ function and detect abnormalities. Recognizing and interpreting clinical findings are essential components of veterinary practice, aiding in the identification of diseases, monitoring treatment progress, and guiding therapeutic interventions. This page brings together peer-reviewed research studies and scholarly articles that explore the methodologies, interpretations, and implications of clinical findings in the context of equine health care.
Clinicopathologic evidence of myocardial injury in horses with acute abdominal disease.
Journal of the American Veterinary Medical Association    October 20, 2012   Volume 241, Issue 9 1202-1208 doi: 10.2460/javma.241.9.1202
Nath LC, Anderson GA, Hinchcliff KW, Savage CJ.To determine whether there is evidence of myocardial injury in horses with acute abdominal disease. Methods: Prospective case series. Methods: 18 healthy horses and 69 horses with acute abdominal disease. Methods: 18 healthy horses had been admitted to the hospital for investigation and were assigned to group 1. Horses examined for acute abdominal disease were assigned to 3 groups: strangulating obstruction, nonstrangulating obstruction, or inflammatory disease (groups 2, 3, and 4, respectively). Heart rate, Hct, and blood lactate and cardiac troponin I (cTnI) concentrations were measured at i...
Musculoskeletal injury in thoroughbred racehorses: correlation of findings using multiple imaging modalities.
The Veterinary clinics of North America. Equine practice    October 18, 2012   Volume 28, Issue 3 539-561 doi: 10.1016/j.cveq.2012.09.005
Gaschen L, Burba DJ.Adaptive and nonadaptive stress remodeling in Thoroughbred racehorses leads to most of their musculoskeletal injuries, and imaging plays an important role in its detection. Bone scintigraphy is important for detecting stress remodeling and stress fractures and aids in decision making when more than one lesion is present on MRI or radiographic examinations. MRI likely represents the best modality for the assessment of osteoarthritis of the metacarpophalangeal and metatarsophalangeal joints. Ultrasonography remains important as the first modality for the assessment of tendon and ligamentous inju...
Advances in nuclear medicine.
The Veterinary clinics of North America. Equine practice    October 18, 2012   Volume 28, Issue 3 527-538 doi: 10.1016/j.cveq.2012.09.004
Selberg K, Ross M.Nuclear scintigraphy is a mainstay of diagnostic imaging and has preserved its relevance in the imaging of acute and chronic trauma. It is particularly useful in the evaluation of athletic injuries. Pitfalls of interpretation, false negatives and false positives exist as with many imaging modalities. Synthesis of physical exam findings, lameness evaluation and, when possible, diagnostic analgesia in combination with nuclear scintigraphy imaging findings, will allow for the most information to be applied to the patient's clinical problem.
The effects of a loading dose followed by constant rate infusion of xylazine compared with romifidine on sedation, ataxia and response to stimuli in horses.
Veterinary anaesthesia and analgesia    October 11, 2012   Volume 40, Issue 2 157-165 doi: 10.1111/j.1467-2995.2012.00784.x
Ringer SK, Portier K, Torgerson PR, Castagno R, Bettschart-Wolfensberger R.To compare xylazine and romifidine constant rate infusion (CRI) protocols regarding degree of sedation, and effects on postural instability (PI), ataxia during motion (A) and reaction to different stimuli. Methods: Blinded randomized experimental cross-over study. Methods: Ten adult horses. Methods: Degree of sedation was assessed by head height above ground (HHAG). Effects on PI, A and reaction to visual, tactile and acoustic stimulation were assessed by numerical rating scale (NRS) and by visual analogue scale (VAS). After baseline measurements, horses were sedated by intravenous loading dos...
EcPV2 DNA in equine papillomas and in situ and invasive squamous cell carcinomas supports papillomavirus etiology.
Veterinary pathology    October 11, 2012   Volume 50, Issue 4 686-692 doi: 10.1177/0300985812463403
Lange CE, Tobler K, Lehner A, Grest P, Welle MM, Schwarzwald CC, Favrot C.Equine penile papillomas, in situ carcinomas, and invasive carcinomas are hypothesized to belong to a continuum of papillomavirus-induced diseases. The former ones clinically present as small grey papules, while the latter 2 lesions are more hyperplasic or alternatively ulcerated. To test the hypothesis that these lesions are papillomavirus-induced, samples of 24 horses with characteristic clinical and histologic findings of penile papillomas or in situ or invasive squamous cell carcinomas were collected. As controls, 11 horses with various lesions--namely, Balanoposthitis (6 cases), melanoma ...
Intrathoracic pulsion diverticulum in a horse.
The Canadian veterinary journal = La revue veterinaire canadienne    October 2, 2012   Volume 53, Issue 4 408-411 
Yamout SZ, Magdesian KG, Tokarz DA, le Jeune SS.This is a report of a 12-year-old Swedish Warmblood gelding with a ruptured esophageal pulsion diverticulum associated with atypical clinical signs of colic and septic peritonitis on presentation. The location of this diverticulum at the hiatus was unique and was most likely responsible for the unusual presentation of this horse. Diverticule de Zenker intrathoracique chez un cheval. Ceci est un rapport d’un hongre de race Swedish Warmblood âgé de 12 ans présentant un diverticule de Zenker perforé associé à des signes cliniques atypiques de coliques et de péritonite septique à la pré...
MRI findings in 232 horses with lameness localized to the metacarpo(tarso)phalangeal region and without a radiographic diagnosis. King JN, Zubrod CJ, Schneider RK, Sampson SN, Roberts G.Two hundred and thirty-two horses with lameness localized to the metacarpo(tarso)phalangeal (MCP/MTP) region without a radiographic diagnosis were evaluated. All horses had high-field magnetic resonance (MR) imaging of the MCP/MTP region performed for the lame limb and the contralateral limb for comparison. There were 46 horses that had bilateral abnormalities in the forelimbs; 27 of these horses were not lame in the contralateral limb at the time of examination. Bilateral hind limb abnormalities were observed in 37 horses; 22 horses were not lame in the contralateral limb. Soft tissue abnorma...
Benign intraocular teratoid medulloepithelioma causing glaucoma in an 11-year-old Arabian mare.
Veterinary ophthalmology    October 1, 2012   Volume 16, Issue 4 297-302 doi: 10.1111/j.1463-5224.2012.01067.x
Leiva M, Felici F, Carvalho A, Ramis A, Peña T.An 11-year-old Arabian mare was presented for investigation of a visible, pale-colored intraocular mass in the right eye. Results: An intraocular mass was detected clinically and ultrasonographically as originating from the superior temporal quadrant of the ciliary body and iris and causing secondary glaucoma. The echodense mass was occupying the majority of the vitreous chamber and extended into the anterior chamber. The left eye appeared normal. Results: Enucleation was recommended for therapeutic and diagnostic purposes. No adjuvant treatment was given. Histopathological examination demonst...
Fatal musculoskeletal injuries of Quarter Horse racehorses: 314 cases (1990-2007).
Journal of the American Veterinary Medical Association    September 28, 2012   Volume 241, Issue 7 935-942 doi: 10.2460/javma.241.7.935
Sarrafian TL, Case JT, Kinde H, Daft BM, Read DH, Moore JD, Uzal FA, Stover SM.To determine major causes of death and the anatomic location of musculoskeletal injuries in Quarter Horse racehorses in California. Methods: Retrospective case series. Methods: 314 Quarter Horse racehorses with musculoskeletal injuries that were necropsied through the California Horse Racing Board Postmortem Program from 1990 to 2007. Methods: Postmortem pathology reports were retrospectively reviewed. Musculoskeletal injuries were categorized by anatomic region and described. The number of Quarter Horse starts and starters for the same period of time were obtained from a commercial database f...
Ophthalmological findings in a closed herd of Lipizzaners.
Equine veterinary journal    September 26, 2012   Volume 45, Issue 2 209-213 doi: 10.1111/j.2042-3306.2012.00630.x
Rushton J, Tichy A, Brem G, Druml T, Nell B.There are no studies on the ophthalmic health status in the Lipizzaner breed. Objective: To perform an ophthalmological survey in a closed herd in 3 housing systems. Methods: All horses at the Federal Stud Piber, Heldenberg and the Spanish Riding School Vienna were subjected to ophthalmological examination. Findings were documented and correlated with factors such as age, gender, location and housing situation. The interrelation of abnormalities of different regions was determined by calculating accuracy. Pedigree analysis of horses affected by cataract was performed. Results: A total of 267 h...
Pulpar temperature changes during mechanical reduction of equine cheek teeth: comparison of different motorised dental instruments, duration of treatments and use of water cooling.
Equine veterinary journal    September 26, 2012   Volume 45, Issue 3 355-360 doi: 10.1111/j.2042-3306.2012.00650.x
O'Leary JM, Barnett TP, Parkin TD, Dixon PM, Barakzai SZ.Although equine motorised dental instruments are widely used, there is limited information on their thermal effect on teeth. The recently described variation in subocclusal secondary dentine depth overlying individual pulp horns may affect heat transmission to the underlying pulps. Objective: This study compared the effect of 3 different equine motorised dental instruments on the pulpar temperature of equine cheek teeth with and without the use of water cooling. It also evaluated the effect of subocclusal secondary dentine thickness on pulpar temperature changes. Methods: A thermocouple probe ...
Factors influencing foaling rate following colic surgery in pregnant Thoroughbred mares in Central Kentucky.
Equine veterinary journal    September 26, 2012   Volume 45, Issue 3 346-349 doi: 10.1111/j.2042-3306.2012.00652.x
Drumm NJ, Embertson RM, Woodie JB, Ruggles AJ, Hopper SA, Fimmers R, Handler J.Clinical experience has suggested that foaling rates following colic surgery in the pregnant mare are influenced by days of gestation. This premise has not been supported in previous studies. We also aimed to determine the effects of other potential influencing factors. Objective: To determine the influence of age of gestation on foaling rates in pregnant mares following colic surgery and evaluate the relationships between other factors and foaling rates. Methods: Medical records of Thoroughbred mares, which had colic surgery performed from 1993 to 2007 at the Rood and Riddle Equine Hospital, ...
Magnetic resonance imaging of pulp in normal and diseased equine cheek teeth. Gerlach K, Ludewig E, Brehm W, Gerhards H, Delling U.A retrospective analysis of 619 upper and lower cheek teeth from 62 horses was performed. Based on clinical findings, as well as radiographic and magnetic resonance (MR) imaging findings, the teeth were classified into five groups. There were 20 teeth with abnormal MR imaging signals as well as clinical alterations and 599 healthy teeth. Using MR imaging, the appearance of pulp in diseased and disease-free teeth was compared, and the appearance of abnormal pulp was studied. Subsequently, the ability of MR imaging to diagnose pulpitis and pulp necrosis in teeth with normal external appearance w...
Equine multinodular pulmonary fibrosis in association with asinine herpesvirus type 5 and equine herpesvirus type 5: a case report.
Acta veterinaria Scandinavica    September 25, 2012   Volume 54, Issue 1 57 doi: 10.1186/1751-0147-54-57
Back H, Kendall A, Grandón R, Ullman K, Treiberg-Berndtsson L, Ståhl K, Pringle J.A standardbred gelding with a history of 10 days pyrexia and lethargy was referred to the Equine Hospital at the Swedish University of Agricultural Sciences in Uppsala, Sweden.The horse had tachypnea with increased respiratory effort and was in thin body condition. Laboratory findings included leukocytosis, hyperfibrinogenemia and hypoxemia. Thoracic radiographs showed signs of pneumonia with a multifocal nodular pattern, which in combination with lung biopsy findings indicated Equine Multinodular Pulmonary Fibrosis (EMPF). EMPF is a recently described disease in adult horses with clinical s...
Magnetic resonance imaging features of sinonasal disorders in horses. Tessier C, Brühschwein A, Lang J, Konar M, Wilke M, Brehm W, Kircher P.Diseases of paranasal sinuses and nasal passages in horses can be a diagnostic challenge because of the complex anatomy of the head and limitations of many diagnostic modalities. Our hypothesis was that magnetic resonance (MR) imaging would provide excellent anatomical detail and soft tissue resolution, and would be accurate in the diagnosis of diseases of the paranasal sinuses and nasal passages in horses. Fourteen horses were imaged. Inclusion criteria were lesions located to the sinuses or nasal passages that underwent MR imaging and subsequent surgical intervention and/or histopathologic e...
Survival of horses following strangulating large colon volvulus.
Equine veterinary journal    September 19, 2012   Volume 45, Issue 2 219-223 doi: 10.1111/j.2042-3306.2012.00620.x
Suthers JM, Pinchbeck GL, Proudman CJ, Archer DC.The pattern of long-term survival and specific factors associated with long-term survival have not previously been evaluated in horses with a strangulating large colon volvulus (LCV). Objective: To provide data on the long-term survival of horses with LCV and to identify pre-, intra- and post operative variables associated with survival. Methods: Clinical data and long-term follow-up information were obtained from 116 horses with a strangulating LCV (≥360°) undergoing general anaesthesia. Two multivariable Cox proportional hazards models for post operative survival time were developed: Mode...
Farriery for the hoof with low or underrun heels.
The Veterinary clinics of North America. Equine practice    September 18, 2012   Volume 28, Issue 2 351-364 doi: 10.1016/j.cveq.2012.06.002
Hunt RJ.Underrun heels are common and involve hoof capsule distortion in which the horn tubules of the heels undergo bending and lengthening, resulting in decreased strength and functionality. The syndrome varies in clinical presentation, depending on duration, severity of distortion, presence of secondary problems, and presence of lameness. Primary treatment goals are to maintain soundness and functional integrity of the foot and to establish a normal hoof capsule. Resolution of the problem is generally not achieved in horses in a heavy work schedule, and realistic goals in this situation are to main...
Crotalariosis equorum (“jaagsiekte”) in horses in southern Mozambique, a rare form of pyrrolizidine alkaloid poisoning. Botha CJ, Lewis A, du Plessis EC, Clift SJ, Williams MC.Twenty-eight horses in southern Mozambique died after exhibiting severe respiratory distress. At necropsy, the overinflated lungs did not collapse, had prominent rib impressions, and were fibrotic and emphysematous. Microscopically, prominent proliferation of nonciliated epithelial (Clara) cells in the terminal bronchioles and pulmonary fibrosis were observed, indicative of chronic pneumotoxicity. Transmission electron microscopy demonstrated hyperplasia, desquamation, and apical bulging of Clara cells into the bronchiolar lumen. The outbreak was attributed to ingestion of Crotalaria dura J.M....
Farriery for the hoof with a high heel or club foot.
The Veterinary clinics of North America. Equine practice    September 18, 2012   Volume 28, Issue 2 365-379 doi: 10.1016/j.cveq.2012.06.007
O'Grady SE, Dryden VC.A club foot or flexural deformity may affect a horse at any stage of life from neonate through adulthood. The emphasis of this article is on defining and recommending the appropriate farriery for flexural deformities involving the deep digital flexor tendon and the distal interphalangeal joint. Clinical management of the flexural deformity is influenced by the severity, duration, and etiology of the club foot as well as the degree and source of lameness. Also discussed is the management of mismatched hoof angles, which remains a controversial subject for both farrier and veterinarian.
Acupuncture Points of the Horse’s Distal Thoracic Limb: A Neuroanatomic Approach to the Transposition of Traditional Points.
Animals : an open access journal from MDPI    September 17, 2012   Volume 2, Issue 3 455-471 doi: 10.3390/ani2030455
Lancaster LS, Bowker RM.Veterinary acupuncture charts were developed based on the concept of transpositional points whereby human acupuncture maps were adapted to animal anatomy. Transpositional acupuncture points have traditionally been placed in specific locations around the horse's coronet and distal limb believed to be the closest approximation to the human distal limb points. Because the horse has a single digit and lacks several structures analogous to the human hand and foot, precisely transposing all of the human digital points is not anatomically possible. To date there is no published research on the effect...
Content validity of the Rodeo-SCAT.
International journal of sports medicine    September 7, 2012   Volume 34, Issue 2 170-175 doi: 10.1055/s-0032-1311651
Lafave MR, Butterwick DJ, Murray RP, Freeman T, Lau BH.The purpose of this study was to establish the content validity of the Rodeo SCAT for the sport of rodeo and bull riding. The study design was comprised of expert consensus and content validation. A modified Ebel procedure was employed to content validate the rodeo SCAT. Content validation using this method includes experts agreeing on the importance of each item that comprises the rodeo SCAT. This 3-stage process involved: 1) face validation by a local committee: 2) initial expert consensus measurement via distance; and 3) a face-to-face discussion for items that did not originally achieve 80...
Finite element analysis of stress in the equine proximal phalanx.
Equine veterinary journal    September 4, 2012   Volume 45, Issue 3 273-277 doi: 10.1111/j.2042-3306.2012.00635.x
O'Hare LM, Cox PG, Jeffery N, Singer ER.To improve understanding of the internal structure of the proximal phalanx (P1), response of the bone to load and possible relation to the pathogenesis of fractures in P1. Objective: To model the P1 and replicate the loads experienced by the bone in stance, walk, trot and gallop using finite element analysis. Methods: The geometry of the P1 was captured using micro-computed tomography (μCT) and was reconstructed in 3 dimensions. Values for material properties and forces experienced at stance, walk, trot and gallop were taken from the literature and were applied to the reconstructed model. Usi...
Equine keratomycoses in California from 1987 to 2010 (47 cases).
Equine veterinary journal    September 4, 2012   Volume 45, Issue 3 361-366 doi: 10.1111/j.2042-3306.2012.00623.x
Reed Z, Thomasy SM, Good KL, Maggs DJ, Magdesian KG, Pusterla N, Hollingsworth SR.Equine keratomycosis in the western USA has received little study, probably owing to its low prevalence. Objective: To determine clinical features, predominant fungal isolates, treatment modalities and outcomes of horses with keratomycosis in California and compare these with results from different geographic regions. Methods: Records of horses presented to the University of California-Davis Veterinary Medical Teaching Hospital (UCD-VMTH) with confirmed keratomycosis between 1987 and 2010 were reviewed for this retrospective study. Information retrieved from the record included background, oph...
A retrospective study of horses investigated for weight loss despite a good appetite (2002-2011).
Equine veterinary journal    September 4, 2012   Volume 45, Issue 3 340-345 doi: 10.1111/j.2042-3306.2012.00624.x
Metcalfe LV, More SJ, Duggan V, Katz LM.Weight loss despite a good appetite is a frequent diagnostic challenge for equine veterinarians; however, there are few objective reports and little descriptive information regarding risk factors and prognostic indicators. Objective: To provide a descriptive epidemiological analysis of horses evaluated for weight loss despite a good appetite and evaluate relationships between historical and clinicopathological findings and final outcome (survival vs. nonsurvival) to identify risk factors and prognostic indicators. Methods: Medical records of horses referred for investigation of weight loss des...
Ocular abnormalities in healthy Standardbred foals.
Veterinary ophthalmology    September 3, 2012   Volume 16, Issue 4 245-250 doi: 10.1111/j.1463-5224.2012.01063.x
Barsotti G, Sgorbini M, Marmorini P, Corazza M.To determine the prevalence and describe ocular abnormalities in healthy Standardbred foals within 48 h of birth. Methods: One hundred and two neonatal foals. Methods: All foals had an unassisted delivery. On the basis of physical examination and the results of hematological and biochemical parameters, all foals were unaffected by systemic diseases. A complete ophthalmic examination was performed within 48 h of birth. Foals with ocular hemorrhages were re-examined weekly until the abnormalities were resolved. Results: 65/102 (63.7%) foals did not show ocular abnormalities, while in 37/102 (36....
Eastern equine encephalitis: MRI findings in two patients.
Medicine and health, Rhode Island    August 30, 2012   Volume 95, Issue 7 227-229 
Ethier M, Rogg J.No abstract available
Extensive myenteric ganglionitis in a case of equine chronic intestinal pseudo-obstruction associated with EHV-1 infection.
Journal of comparative pathology    August 27, 2012   Volume 148, Issue 4 289-293 doi: 10.1016/j.jcpa.2012.07.004
Pavone S, Sforna M, Gialletti R, Prato S, Marenzoni ML, Mandara MT.A 7-year-old male trotter horse with a history of recurrent colic displayed clinical findings consistent with chronic intestinal pseudo-obstruction (CIP). At laparotomy, an impaction of the descending colon associated with marked atrophy of the right dorsal colon was found. The horse was humanely destroyed and tissues collected at necropsy examination revealed diffuse enteric ganglionitis comprising an infiltrate of CD3(+) T lymphocytes and plasma cells. At all levels of the intestinal tract the number of myenteric ganglia and of normal ganglion cells was decreased significantly. There were ch...
Liver lobe torsion in six horses.
Journal of the American Veterinary Medical Association    August 25, 2012   Volume 241, Issue 5 615-620 doi: 10.2460/javma.241.5.615
Tennent-Brown BS, Mudge MC, Hardy J, Whelchel DD, Freeman DE, Fischer AT.6 horses were determined to have torsion of a liver lobe at 4 referral institutions over a 21-year period. Results: Clinical findings were nonspecific but often included signs of marked inflammation. Two of the 6 horses were examined because of colic, and 2 were assessed because of peritonitis that failed to respond to treatment; the remaining 2 horses were examined because of nonspecific clinical signs that included inappetence, lethargy, and weight loss. The results of laboratory tests were widely variable, and values for liver enzyme activities were typically within reference limits or only...
Pyogranulomatous lesion causing neurological signs localised to the sacral region in a horse.
Australian veterinary journal    August 23, 2012   Volume 90, Issue 10 392-394 doi: 10.1111/j.1751-0813.2012.00982.x
Cudmore LA, Groenendyk JC, Hodge P, Church S.This case report describes neurological signs associated with a pyogranulomatous lesion within the sacral vertebral canal of a horse. The clinical findings included urinary overflow incontinence and reduced anal, perianal and tail tone. The horse failed to respond to medical management and a guarded prognosis for return to athletic performance initiated the decision for euthanasia.
Right dorsal displacement of the large colon as a cause of surgical colic in three foals in New Zealand.
New Zealand veterinary journal    August 21, 2012   Volume 60, Issue 6 360-364 doi: 10.1080/00480169.2012.694406
Hennessy SE, Fraser BS.Over a 3-year period between July 2008 and July 2011, 10 exploratory laparotomies were performed on foals in a Waikato referral facility in New Zealand. Results: Right dorsal displacement of the large colon (RDDLC) was identified during four exploratory laparotomies in three foals that presented for mild-to-moderate colic that was non-responsive to medical management. One foal required a repeat laparotomy 7 weeks post initial surgery, and RDDLC was again diagnosed. Methods: Right dorsal displacement of the large colon in foals. Conclusions: Further investigation may identify risk factors or ma...
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