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Topic:Complications

Complications in horses refer to unexpected medical or surgical issues that arise during the course of treatment or recovery. These complications can affect various systems within the horse's body and may result from underlying conditions, medical interventions, or environmental factors. Common complications in equines include laminitis, colic, infections, and respiratory issues. Each complication presents distinct clinical challenges and requires careful management to mitigate adverse outcomes. This section compiles peer-reviewed research studies and scholarly articles that explore the incidence, etiology, management strategies, and outcomes associated with complications in equine health.
Identification of Arcanobacterium haemolyticum isolated from postcastrational complications of a horse.
Folia microbiologica    January 21, 2011   Volume 55, Issue 6 666-668 doi: 10.1007/s12223-010-0108-4
Hijazin M, Ulbegi-Mohyla H, Alber J, Lämmler C, Hassan AA, Prenger-Berninghoff E, Weiss R, Zschöck M.An Arcanobacterium haemolyticum strain isolated from a postcastrational lesion of a horse was identified phenotypically and genotypically. The latter was performed by sequencing the 16S-23S rDNA intergenic spacer region (ISR), by amplification of the gene encoding A. haemolyticum phospholipase D, by amplification of A. haemolyticum specific parts of ISR-23S rDNA and by amplification of the newly described CAMP factor family protein encoding gene of A. haemolyticum. This indicates (as described previously for seven additional A. haemolyticum strains; Hassan et al. 2009) that A. haemolyticum see...
Standing hand-assisted laparoscopic ovariectomy in 65 mares.
Veterinary surgery : VS    December 23, 2010   Volume 40, Issue 1 90-92 doi: 10.1111/j.1532-950X.2010.00771.x
Goodin JT, Rodgerson DH, Gomez JH.To review the efficacy and safety of unilateral ovariectomy by use of a standing hand-assisted laparoscopic approach and evaluate the effect of ovary size on posttransection hemorrhage after application of a linear stapling device. Methods: Case series. Methods: Horses (n=65) aged 2-20 years. Methods: Medical records of mares that had ovariectomy performed by use of a standing hand-assisted laparoscopic approach were reviewed. Data retrieved were signalment, ovary removed (left, right), ovarian size, ovarian pathology, intraoperative and postoperative complications, and length of hospitalizati...
Evaluation of a novel post operative treatment for sinonasal disease in the horse (1996-2007).
Equine veterinary journal    December 15, 2010   Volume 43, Issue 1 24-29 doi: 10.1111/j.2042-3306.2010.00133.x
Hart SK, Sullins KE.Results of surgical treatment of sinonasal disease in horses have been reported previously; however, this paper describes the outcome of horses in which a specific post operative treatment protocol was used. Objective: The objectives of the study were to determine: 1) short- and long-term outcome; 2) complications; and 3) recurrence rates of different disease processes, when horses were treated with a specific treatment protocol. Methods: Medical records of horses presented for surgical treatment of sinonasal disease from 1996-2007 were reviewed. Results and duration of surgical exploration we...
Treatment of type 2 and 4 olecranon fractures with locking compression plate osteosynthesis in horses: a prospective study (2002-2008).
Veterinary and comparative orthopaedics and traumatology : V.C.O.T    November 19, 2010   Volume 24, Issue 1 57-61 doi: 10.3415/VCOT-10-02-0020
Jackson M, Kummer M, Auer J, Hagen R, Fuerst A.This prospective study describes a series of 18 olecranon fractures in 16 horses that were treated with locking compression plates (LCP). Twelve of the 18 fractures were simple (type 2), whereas six were comminuted (type 4). Six fractures were open and 12 were closed. Each horse underwent LCP osteosynthesis consisting of open reduction and application of one or two LCP. Complete fracture healing was achieved in 13 horses. Three horses had to be euthanatized: two because of severe infection and one because of a comminuted radial fracture 11 days after fixation of the olecranon fracture. Complic...
Wooden, metallic, hair, bone, and plant foreign bodies in horses: 37 cases (1990-2005).
Journal of the American Veterinary Medical Association    November 16, 2010   Volume 237, Issue 10 1173-1179 doi: 10.2460/javma.237.10.1173
Farr AC, Hawkins JF, Baird DK, Moore GE.To characterize features of diagnosis, treatment, and outcome in horses with foreign bodies, exclusive of enteric, inhaled, and foot-penetrating foreign bodies. Methods: Retrospective case series. Methods: 37 horses with foreign bodies. Methods: The incidence of equine foreign bodies from 1990 through 2005 was determined by review of data from veterinary schools participating in the Veterinary Medical Database (VMDB). Medical records of horses with foreign bodies at Purdue University were reviewed, and the following information was retrieved: clinical history; signalment; results of physical, ...
Occurrence of incisional complications and associated risk factors using a right ventral paramedian celiotomy incision in 159 horses.
Veterinary surgery : VS    November 9, 2010   Volume 40, Issue 1 82-89 doi: 10.1111/j.1532-950X.2010.00750.x
Anderson SL, Vacek JR, Macharg MA, Holtkamp DJ.To evaluate the occurrence of, and variables associated with, incisional complications after right ventral paramedian celiotomy in horses. Methods: Case series. Methods: Horses (n=159). Methods: Occurrence of incisional complications after right ventral paramedian celiotomy was determined in 159 horses (161 celiotomies) that survived at least 30 days after surgery at a private equine hospital (2003-2007). Follow-up information for 121 horses was obtained ≥90 days after surgery. Univariate analysis and multivariate logistic regression was performed to evaluate variables associated with incisi...
Comparison of complications and long-term survival rates following hand-sewn versus stapled side-to-side jejunocecostomy in horses with colic.
Journal of the American Veterinary Medical Association    November 3, 2010   Volume 237, Issue 9 1060-1067 doi: 10.2460/javma.237.9.1060
Freeman DE, Schaeffer DJ.To evaluate survival rate and complications after jejunocecostomy in horses with colic and to compare outcomes after hand-sewn versus stapled side-to-side jejunocecostomy. Methods: Retrospective cohort study. Methods: 32 horses. Methods: Information was retrieved from medical records and through telephone calls on horses that had a hand-sewn or stapled side-to-side jejunocecostomy for treatment of colic, which was performed by or under the supervision of the same surgeon. Kaplan-Meier life table analysis was used to compare survival times and rates between horses that underwent a hand-sewn or ...
Long-term outcome after implantation of a suprachoroidal cyclosporine drug delivery device in horses with recurrent uveitis.
Veterinary ophthalmology    September 16, 2010   Volume 13, Issue 5 294-300 doi: 10.1111/j.1463-5224.2010.00807.x
Gilger BC, Wilkie DA, Clode AB, McMullen RJ, Utter ME, Komaromy AM, Brooks DE, Salmon JH.To determine the long-term efficacy, complications, and duration of effect of a cyclosporine (CsA) suprachoroidal implant (CSI) in horses with equine recurrent uveitis (ERU). Methods: Horses with ERU were treated with a 6-mm diameter, 25 mg, reservoir matrix CsA implant in the deep sclera adjacent to the suprachoroidal space. Horses with follow-up >1 year were examined for frequency of uveitis episodes, complications, and vision at last recheck. Results: Data from 151 eyes of 133 horses from the USA and Europe that had CsA devices implanted for ERU were reviewed. Follow-up time ranged from 13 ...
Extraction of cheek teeth using a lateral buccotomy approach in 114 horses (1999-2009).
Equine veterinary journal    August 26, 2010   Volume 43, Issue 3 348-353 doi: 10.1111/j.2042-3306.2010.00169.x
O'Neill HD, Boussauw B, Bladon BM, Fraser BS.There are few published data regarding the success rates of cheek tooth (CT) removal by lateral buccotomy in the horse. Objective: A retrospective study of 114 horses admitted to 2 private equine referral hospitals over a 10 year period (1999-2009), which underwent CT removal via a lateral buccotomy. Methods: Hospital records were analysed and details including case details, presenting complaint and results of all diagnostic tests and surgical reports were documented. Information obtained during post operative reassessment was also available for analysis. Long-term follow-up information (>2 mo...
Extraluminal, C shaped polyethylene prostheses in two ponies with tracheal collapse.
Veterinary surgery : VS    August 14, 2010   Volume 39, Issue 6 776-783 doi: 10.1111/j.1532-950X.2010.00715.x
Busschers E, Epstein KL, Holt DE, Parente EJ.To describe the surgical technique, complications, and outcome after use of extraluminal prostheses in 2 ponies with severe tracheal collapse. Methods: Clinical report. Methods: Ponies (n=2) with severe tracheal collapse. Methods: A ventral median approach was used to expose the trachea from the larynx to the manubrium. Extraluminal, high-density polyethylene, C-shaped prostheses were sutured to the dorsal tracheal membrane and tracheal rings to provide external tracheal support. Results: The surgical approach provided good tracheal access and placement of the rings was uncomplicated. Initial ...
Removal of 11 incompletely erupted, impacted cheek teeth in 10 horses using a dental alveolar transcortical osteotomy and buccotomy approach.
Veterinary surgery : VS    August 12, 2010   Volume 39, Issue 7 884-890 doi: 10.1111/j.1532-950X.2010.00724.x
Tremaine WH, McCluskie LK.To describe surgical technique and outcome in 10 horses with impacted cheek teeth that were removed by a transcortical osteotomy and buccotomy technique. Methods: Case series. Methods: Horses (n=10) with impacted cheek teeth. Methods: Medical records (2002-2008) of horses with impacted cheek teeth requiring removal were reviewed; surgical technique and outcome were determined. Results: Exodontia of 11 cheek teeth was performed surgically in 10 horses; 3 horses had complications (residual swelling of the mandible) that resolved and all horses returned to their previous use. Conclusions: Transco...
Clinical features and prognostic variables in 109 horses with esophageal obstruction (1992-2009).
Journal of veterinary internal medicine    August 12, 2010   Volume 24, Issue 5 1147-1152 doi: 10.1111/j.1939-1676.2010.0573.x
Chiavaccini L, Hassel DM.Esophageal obstruction is common in horses and can result in life-threatening complications. Previous studies have described clinical findings in horses with esophageal obstruction, but there are no reports that attempt to make correlations of clinical findings with outcome. Objective: Specific clinical features of horses with esophageal obstruction are associated with increased likelihood of complications. Methods: One hundred and nine horses with esophageal obstruction. Methods: Retrospective cross-sectional study. All clinical records of horses admitted between April 1992 and February 2009 ...
Evaluation of a transvaginal laparoscopic natural orifice transluminal endoscopic surgery approach to the abdomen of mares.
Veterinary surgery : VS    August 12, 2010   Volume 39, Issue 7 873-878 doi: 10.1111/j.1532-950X.2010.00722.x
Alford C, Hanson R.To report natural orifice transluminal endoscopic surgery (NOTES) using laparoscopic and endoscopic instrumentation transvaginally into the mare's abdomen and identify structures visible using this approach. Methods: Descriptive experimental study. Methods: Mares (n=8). Methods: A standing, transvaginal approach was made in the cranial vaginal vault at either the 1 (right; 4 mares) or 11 (left; 4 mares) o'clock position relative to the cervix. The abdomen was visually explored and the viscera evaluated using a 2 m flexible endoscope followed by a 62 cm laparoscope. Incisional healing was monit...
Thoracoscopic lung biopsies in heaves-affected horses using a bipolar tissue sealing system.
Veterinary surgery : VS    August 3, 2010   Volume 39, Issue 7 839-846 doi: 10.1111/j.1532-950X.2010.00720.x
Relave F, David F, Leclère M, Alexander K, Hélie P, Meulyzer M, Lavoie JP, Marcoux M.To validate the use of the LigaSure™ Vessel Sealing System (LVSS) to perform thoracoscopic lung tissue biopsies in heaves-affected horses. Methods: Prospective clinical study. Methods: Heaves-affected horses (n=12). Methods: Lung biopsies (n=34) were collected with the LVSS (2-4 biopsies/horse) in horses with and without clinical signs of heaves. Thoracoscope (13th intercostal space [ICS]) and 2 instruments (between the 12-15th ICS) portals were used. Selected clinical and arterial blood gas variables were monitored. Postoperative pneumothorax was evaluated. Depth of thermal injury to the su...
Standing lateral thoracotomy in horses: indications, complications, and outcomes.
Veterinary surgery : VS    August 3, 2010   Volume 39, Issue 7 847-855 doi: 10.1111/j.1532-950X.2010.00713.x
Hilton H, Aleman M, Madigan J, Nieto J.To describe the indications for, complications arising from, and outcome of horses that had standing lateral thoracotomy for pleural or pericardial disease. Methods: Case series. Methods: Horses (n=16). Methods: Medical records (January 1990-December 2008) of sedated standing horses that had lateral thoracotomy were reviewed. Clinical and surgical findings, perioperative and short-term complications were recorded. Long-term (>6 months) outcome was determined through telephone conversations with owners and veterinarians. Results: Mean (±SD) horse age was 6.6±5.3 years (range, 1-15 years). ...
Outcome and long-term follow-up of 20 horses undergoing surgery for caecal impaction: a retrospective study (2000-2008).
Equine veterinary journal    July 20, 2010   Volume 42, Issue 5 388-392 doi: 10.1111/j.2042-3306.2010.00087.x
Smith LC, Payne RJ, Boys Smith SJ, Bathe AP, Greet TR.If untreated, caecal impaction may progress to rupture of the caecum and reports of long-term outcome for horses undergoing surgery for caecal impaction are required. Objective: To describe short- and long-term complication rates for horses undergoing surgery for caecal impaction in an otherwise life-threatening gastrointestinal condition. Methods: Case records were reviewed for horses undergoing surgery for caecal impaction. Horses were included in the study if an abnormally large, fluid-distended or feed-impacted caecum was the primary diagnosis at surgery and excluded if the caecum had alre...
Risk factors for incisional complications after exploratory celiotomy in horses: do skin staples increase the risk?
Veterinary surgery : VS    July 20, 2010   Volume 39, Issue 5 616-620 doi: 10.1111/j.1532-950X.2009.00636.x
Torfs S, Levet T, Delesalle C, Dewulf J, Vlaminck L, Pille F, Lefere L, Martens A.To assess risk factors for celiotomy incisional infection in horses, especially the use of staples for skin closure. Methods: Case series. Methods: Horses (n=356) that had 1 exploratory celiotomy for colic and survived >2 weeks after surgery between March 1, 2004 and December 31, 2007. Methods: Incisions were classified as "normal" (no complication, only edema, serous drainage lasting <24 hours) or as "surgical site infection (SSI)" (persistent serosanguinous drainage or purulent drainage with or without positive bacterial culture). All possible risk factors, including method of skin closure (...
Use of a pinless external fixator for unilateral mandibular fracture repair in nine equids.
Veterinary surgery : VS    June 18, 2010   Volume 39, Issue 6 761-764 doi: 10.1111/j.1532-950X.2010.00709.x
Haralambus RM, Werren C, Brehm W, Tessier C.To report use of a pinless external fixator (PEF) for unilateral mandibular fractures in 9 equids. Methods: Case series. Methods: Equids (n=9) with unilateral mandibular fractures. Methods: All fractures were stabilized with the AO/ASIF PEF using a minimum of 4 clamps, under general anesthesia. Fracture configuration, complications, outcome, and owner satisfaction were evaluated. Results: All fractures were stabilized; 2 equids were euthanatized; 1 because of an inability to stand after surgery and 1 because of owner decision after PEF dislodgement. Seven repairs healed with good outcome and o...
Difference in incisional complications following exploratory celiotomies using antibacterial-coated suture material for subcutaneous closure: Prospective randomised study in 100 horses.
Equine veterinary journal    June 9, 2010   Volume 42, Issue 4 304-309 doi: 10.1111/j.2042-3306.2009.00020.x
Bischofberger AS, Brauer T, Gugelchuk G, Klohnen A.Incisional complications are a major post operative challenge following ventral midline exploratory celiotomy for abdominal pain in horses. They lead to discomfort, prolonged hospitalisation, longer recovery times and increased cost; therefore, investigation of preventative procedures are warranted. Objective: To determine the clinical effect of antibacterial (triclosan) coated 2-0 polyglactin 910 suture material on the likelihood of incisional infections when used for closure of subcutaneous tissue following ventral midline celiotomies in horses. Methods: One hundred horses undergoing explora...
A case of disseminated infection caused by Streptococcus equi subspecies zooepidemicus. Poulin MF, Boivin G.Human infections with Streptococcus equi subspecies zooepidemicus, a group C streptococcus, are very rare and are generally associated with contact with horses, and consumption of unpasteurized milk products, goat cheese or pork. In most cases S zooepidemicus leads to fulminant infections. The case of a middle-aged woman who had sporadic contact with horses is described in the present report. She developed a bacteremia with severe and extensive complications that included meningitis, mitral endocarditis and blindness due to bilateral endophthalmitis. To the authors' knowledge, this is the firs...
Semiconductor diode laser transscleral cyclophotocoagulation for the treatment of glaucoma in horses: a retrospective study of 42 eyes.
Veterinary ophthalmology    May 27, 2010   Volume 13, Issue 3 204-209 doi: 10.1111/j.1463-5224.2010.00779.x
Annear MJ, Wilkie DA, Gemensky-Metzler AJ.To evaluate the outcome of diode laser transscleral cyclophotocoagulation (TSCP) for the treatment of glaucoma in horses. Methods: Medical records at The Ohio State University were reviewed. All horses that underwent diode laser TSCP between the years of 1995 and 2007 were included. Preoperative, procedural and clinical follow-up data were collected, and telephone follow-up was performed. Results: Forty-two eyes of 36 horses were included. Twenty-four hours prior to surgery mean intraocular pressure (IOP) was 37.17 + or - 13.48 mmHg (42 eyes). Forty-one of 42 eyes (98%) were sighted and 39 of ...
Standing laparoscopic ovariectomy technique with intraabdominal dissection for removal of large pathologic ovaries in mares.
Veterinary surgery : VS    May 6, 2010   Volume 39, Issue 6 737-741 doi: 10.1111/j.1532-950X.2010.00695.x
De Bont MP, Wilderjans H, Simon O.To describe a standing laparoscopic ovariectomy technique with intraabdominal ovarian dissection inside a specimen retrieval bag for removal of large pathologic ovaries through small incisions. Methods: Case series. Methods: Mares (n=43) aged 2-21 years and weighing 380-680 kg. Methods: Unilateral laparoscopic ovariectomy was performed on 43 standing sedated mares. Ovaries were approached via 3 portal sites, 2 in the paralumbar fossa and a 3rd between the 17th and 18th ribs on the ipsilateral side. Ovaries were dissected free using either a LiNA Tripol-bipolar laparoscopic forceps or a Ligasur...
Physical and clinicopathologic findings in foals derived by use of somatic cell nuclear transfer: 14 cases (2004-2008).
Journal of the American Veterinary Medical Association    May 4, 2010   Volume 236, Issue 9 983-990 doi: 10.2460/javma.236.9.983
Johnson AK, Clark-Price SC, Choi YH, Hartman DL, Hinrichs K.To describe the health status of foals derived by use of somatic cell nuclear transfer (NT) at a university laboratory. Methods: Retrospective case series. Methods: 14 live-born NT-derived foals. Methods: Medical records from 2004 through 2008 were evaluated to identify all pregnancies resulting in live-born NT-derived foals. Information obtained included gestation length, birth weight, foaling complications, gross abnormalities of the fetal membranes, appearance of the umbilicus, mentation of the foal, limb deformities, and any other abnormalities detected in the neonatal period. Clinicopatho...
Osteomyelitis and osteonecrosis after intraosseous perfusion with gentamicin.
Veterinary surgery : VS    April 29, 2010   Volume 39, Issue 5 644-648 doi: 10.1111/j.1532-950X.2010.00685.x
Parker RA, Bladon BM, McGovern K, Smith KC.To describe and discuss previously unreported complications associated with intraosseous perfusion with gentamicin in horses. Methods: Case report. Methods: Ten-year-old Warmblood gelding. Methods: Intraosseous perfusion with gentamicin into the proximal phalanx (P1) was used as part of the treatment regimen for distal interphalangeal joint and navicular bursa synovial sepsis. Although the sepsis responded favorably complications developed at the perfusion site, including persistent osteomyelitis, progressive osteonecrosis, and ultimately pathologic fracture of P1. Results: The progression of ...
Resection and anastomosis of the descending colon in 43 horses.
Veterinary surgery : VS    April 29, 2010   Volume 39, Issue 6 748-753 doi: 10.1111/j.1532-950X.2010.00700.x
Prange T, Holcombe SJ, Brown JA, Dechant JE, Fubini SL, Embertson RM, Peroni J, Rakestraw PC, Hauptman JG.To determine (1) the short- (to hospital discharge) and long- (>6 months) term survival, (2) factors associated with short-term survival, and (3) the perioperative course for horses with resection and anastomosis of the descending colon. Methods: Multicentered case series. Methods: Horses (n=43) that had descending colon resection and anastomosis. Methods: Medical records (January 1995-June 2009) of 7 equine referral hospitals were reviewed for horses that had descending colon resection and anastomosis and were recovered from anesthesia. Retrieved data included history, results of clinical and...
Pararectal cystotomy for urolith removal in nine horses.
Veterinary surgery : VS    April 29, 2010   Volume 39, Issue 5 654-659 doi: 10.1111/j.1532-950X.2010.00689.x
Abuja GA, García-López JM, Doran R, Kirker-Head CA.To report outcome of horses after standing pararectal cystotomy for removal of uroliths. Methods: Case series. Methods: Horses (n=9) with cystic calculi. Methods: Medical records (December 1998-May 2007) of horses with cystic calculi that had standing pararectal cystotomy were reviewed. Signalment; urolith number, size, and type; surgical technique; sedation and analgesia protocols; intra- and postoperative complications and outcome were analyzed. Results: Uroliths (mean diameter, 6.37 cm; median, 6 cm; range, 3-10 cm) were removed intact without need for fragmentation. Eight (89%) horses had ...
Postoperative complications and survival after enterolith removal from the ascending or descending colon in horses.
Veterinary surgery : VS    March 24, 2010   Volume 39, Issue 5 609-615 doi: 10.1111/j.1532-950X.2010.00647.x
Pierce RL, Fischer AT, Rohrbach BW, Klohnen A.To compare incidence of postoperative complications and survival of horses that had surgery for enterolithiasis of the ascending (AC) or descending (DC) colon. Methods: Case series Methods: Horses (n=236) that had celiotomy for AC (n=97) or DC (n=139) enterolithiasis. Methods: Medical records (1999-2005) were reviewed for signalment, presenting clinical signs, surgical findings, postoperative complications, and short-term survival until discharge. Information on performance and survival > or = 1 year was obtained by telephone or mailed questionnaire. Results: Number of postoperative complicati...
Induration of the cricoid cartilage complicates prosthetic laryngoplasty in a horse.
Veterinary surgery : VS    March 10, 2010   Volume 39, Issue 1 128-130 doi: 10.1111/j.1532-950X.2009.00575.x
Tatarniuk DM, Carmalt JL, Allen AL.To report intraoperative complications during needle penetration and suture placement through the cricoid cartilage during a prosthetic laryngoplasty procedure. Methods: Case report. Methods: An 11-year-old American Paint gelding with grade IV left laryngeal hemiplegia underwent a terminal prosthetic laryngoplasty for teaching purposes. Passage of the needle through the cricoid cartilage was difficult and resulted in needle breakage before eventual success using a new needle. The larynx was examined postmortem. Results: Palpation of the larynx revealed hardening of the cricoid cartilage. Radio...
Inflammatory reaction to implanted equine pericardium xenograft.
The Journal of foot and ankle surgery : official publication of the American College of Foot and Ankle Surgeons    December 21, 2009   Volume 49, Issue 2 155-158 doi: 10.1053/j.jfas.2009.10.003
DeCarbo WT, Feldner BM, Hyer CF.Equine pericardium xenograft is now widely used to augment Achilles tendon repair. In this article, we describe the case of a postoperative complication in a healthy 37-year-old male who underwent primary repair, augmented with equine pericardium, of his acutely ruptured Achilles tendon. At 4 months postoperative, an indurated and fluctuant subcutaneous soft tissue reaction was noted at the repair site. Further questioning led the patient to recall having an allergy to horses, although it had been a very long time since he had experienced any symptoms related to the allergy and, as such, he fa...
Evaluation of indwelling intravenous catheters for the regional perfusion of the limbs of horses.
The Veterinary record    October 27, 2009   Volume 165, Issue 17 496-501 doi: 10.1136/vr.165.17.496
Kelmer G, Catasus CT, Saxton AM, Elliot SB.The feasibility of maintaining indwelling intravenous catheters in the saphenous, cephalic or palmar digital vein of horses for seven days to infuse antimicrobial drugs was investigated in 18 horses. The horses were randomly assigned to six groups according to the vein catheterised and whether they received amikacin or erythromycin. None of the catheters was replaced more than once, and 11 of the 18 catheters remained patent for all seven days. Neither the drug administered nor the vein catheterised significantly affected the survival of the catheter. In all but three cases, complications, inc...
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