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Topic:Diagnosis

Diagnosis in horses involves the systematic identification of diseases and conditions affecting equine health. This process relies on a combination of clinical evaluations, laboratory tests, imaging techniques, and other diagnostic tools to assess the health status of horses. Veterinarians utilize these methods to identify symptoms, determine the underlying causes of health issues, and formulate appropriate treatment plans. Diagnostic procedures in equine medicine can include blood tests, ultrasound, radiography, endoscopy, and more specialized tests such as genetic screening or advanced imaging modalities like MRI and CT scans. This page aggregates peer-reviewed research studies and scholarly articles that explore various diagnostic techniques, their applications, and advancements in the field of equine veterinary medicine.
Equine glandular gastric disease: prevalence, impact and management strategies.
Veterinary medicine (Auckland, N.Z.)    July 16, 2019   Volume 10 69-76 doi: 10.2147/VMRR.S174427
Banse HE, Andrews FM.Equine glandular gastric disease (EGGD) is an increasingly recognized disease of the glandular mucosa of the equine stomach. Diagnosis is confirmed by gastric endoscopy and scored based upon one of several different endoscopic scoring systems. Prevalence appears to be variable, depending upon breed and discipline. Primary identified risk factors include exercise frequency, and stress; therefore, management strategies are focused on reducing exercise and stress. Limiting grain intake and increasing pasture turnout may also be helpful preventative measures. Pharmacologic treatment consists prima...
Ultrasonographic findings post laryngoplasty in the horse. Miller S, Carstens A.Laryngoplasty is commonly used to treat laryngeal hemiplegia in Thoroughbred racehorses. Evaluation of the success of the laryngoplasty is traditionally determined using endoscopy. Laryngeal ultrasonography and normal ultrasonographic appearance have been reported in the standing horse, but post-laryngoplasty and ventriculectomy ultrasonographic evaluation has limited literature coverage. A prospective case series of 10 Thoroughbred racehorses with left laryngeal hemiplegia was examined ultrasonographically and endoscopically prior to 3-10 days, 30-50 days, and 6-12 months after laryngoplasty ...
Evaluation of four techniques for injection of the proximal interphalangeal joint in horses.
Veterinary surgery : VS    July 16, 2019   Volume 48, Issue 8 1437-1443 doi: 10.1111/vsu.13296
Mereu M, Hawkes C, Cuddy LC, Perez Olmos JF, Pazzola M, McNally TP.To describe a dorsoproximal midline (DPM) standing technique for proximal interphalangeal joint (PIPJ) injection and to compare it to established dorsolateral flexed (DLF), palmaroproximal (PP), and dorsolateral standing (DLS) techniques. Methods: Ex vivo study. Methods: Sixty cadaver equine thoracic limbs. Methods: Limbs were divided into four groups (n = 15 each group), DLF, DPM, PP, and DLS. For each technique, three operators injected radiopaque contrast and methylene blue into the PIPJ in five limbs. The number of attempts required was recorded. Successful injection was confirmed by radio...
Oral Lesions in the Bit Area in Finnish Trotters After a Race: Lesion Evaluation, Scoring, and Occurrence.
Frontiers in veterinary science    July 12, 2019   Volume 6 206 doi: 10.3389/fvets.2019.00206
Tuomola K, Mäki-Kihniä N, Kujala-Wirth M, Mykkänen A, Valros A.Oral lesions in the bit area are common in horses, but not comprehensively studied in harness racing horses. This study describes the type and occurrence of oral soft tissue lesions in the area affected by the bit, hereafter called the bit area, in trotters after a race. Based on our results, we suggest a system for scoring lesions according to size, type (bruise or wound), age, and depth (superficial or deep). The data was collected during a welfare program for trotters, conducted by The Finnish Trotting and Breeding Association (Suomen Hippos ry). The rostral part of the mouth of 261 horses ...
Internal fixation of a complete ventral luxation of the dens axis in an American quarter horse yearling.
Veterinary surgery : VS    July 12, 2019   Volume 48, Issue 8 1500-1506 doi: 10.1111/vsu.13283
Schulze N, Ehrle A, Noguera Cender AC, Lischer C.To report surgical treatment of a complete luxation of the atlantoaxial articulation with a 4.5-mm T-locking compression plate (T-LCP) in a horse. Methods: Case report. Methods: A one-year-old American quarter horse filly. Methods: A one-year-old American quarter horse filly presented with a complete luxation of the atlantoaxial articulation. Closed and open reduction of the luxation were attempted under general anesthesia with the aid of a pulley system. Because the manual reduction was unsuccessful, the dens axis was excised, and the atlas and axis were stabilized with a 4.5-mm T-LCP. Fo...
The diagnostic performance of human urinary dipsticks to estimate urine pH, specific gravity (SpG), and protein in horses: are they reliable?
BMC veterinary research    July 12, 2019   Volume 15, Issue 1 242 doi: 10.1186/s12917-019-1998-2
Hekmatynia F, Eskandarzadeh N, Imani M, Rezaei M, Zamani-Ahmadmahmudi M.Urinalysis is a critical diagnostic test which is performed in routine veterinary medicine practice. In this diagnostic test, semiquantitative measurement of urine biochemical substances is carried out using urinary dipstick. In the current study, we evaluated the diagnostic performance of human urinary dipsticks to estimate pH, specific gravity (SpG), and protein in 80 urine specimens collected from horses. These parameters were measured using two commercial human dipsticks (KP and MN in abbreviation) and quantitative reference methods. The reference methods for pH, SpG, and protein were pH m...
Actinobacillus species isolated from Japanese Thoroughbred racehorses in the last two decades.
The Journal of veterinary medical science    July 11, 2019   Volume 81, Issue 9 1234-1237 doi: 10.1292/jvms.19-0192
Uchida-Fujii E, Niwa H, Kinoshita Y, Nukada T.Actinobacillus species are known to be pathogenic to horses. To clarify etiological agents of actinobacillosis in Japanese adult horses, 27 isolates from Japanese Thoroughbred racehorses putatively identified by matrix-assisted laser desorption ionization time-of-flight mass spectrometry as Actinobacillus were further identified by PCR of the A. equuli toxin gene, by CAMP test, and by 16S rRNA sequencing analysis. Actinobacillus equuli subsp. haemolyticus was isolated most frequently (16/27) and was related to respiratory infections. Actinobacillus equuli subsp. equuli (4/27) was isolated from...
Assessment of body fluids and blood parameters associated with rapid weight change in heavy horses.
The Canadian veterinary journal = La revue veterinaire canadienne    July 10, 2019   Volume 60, Issue 7 721-724 
Greco-Otto P, Léguillette R.Horses competing in pulling competitions often undergo rapid weight change to enter lower weight categories. The aim of this study was to assess weight change and the associated changes of body water compartments in pulling horses. Weight change was attributed primarily to body water losses; however, losses from other sources were also indicated. . Les chevaux participant à des compétitions de trait subissent souvent des changements de poids rapides pour s’inscrire à des catégories de poids inférieurs. Le but de cette étude consistait à évaluer le changement de poids et les changemen...
Normograde nasolacrimal placement of an ocular-lavage system for treatment of equine eye diseases.
The Canadian veterinary journal = La revue veterinaire canadienne    July 10, 2019   Volume 60, Issue 7 744-748 
Dennis DA, Pinard CL, Kenney DG, Salcedo RJ, Trout DR.The standard placement of a subpalpebral lavage system may not be feasible in some horses with eyelid disease. We describe placement of a commercially available, indwelling nasolacrimal lavage system that circumvents eyelid perforation. This novel approach provided for effective delivery of drugs to 1 horse with periocular and corneal disease. . Le placement standard d’un système de lavage subpalpébral peut ne pas être réalisable chez certains chevaux atteints de maladies oculaires. Nous décrivons le placement d’un système de lavage nasolacrymal à demeure qui évite la perforation d...
Reliability of three common fecal egg counting techniques for detecting strongylid and ascarid infections in horses.
Veterinary parasitology    July 10, 2019   Volume 272 53-57 doi: 10.1016/j.vetpar.2019.07.001
Nápravníková J, Petrtýl M, Stupka R, Vadlejch J.The detection and quantification of nematode eggs using fecal egg count techniques have an irreplaceable role in equine parasitic control. The reliability, particularly precision and accuracy, of individual techniques have been described only for strongylid infections. The aim of this study was to compare three fecal egg count techniques used for the detection of the two most common equine nematode infections: strongylid and ascarid. The Simple McMaster, Concentration McMaster and Mini-FLOTAC techniques were tested on spiked fecal samples with various levels of egg concentration (50, 100, 200,...
Determining factors and interspecific modeling for serum amyloid a concentrations in working horses, donkeys, and mules.
Research in veterinary science    July 9, 2019   Volume 125 256-265 doi: 10.1016/j.rvsc.2019.07.004
Kay G, Tligui N, Semmate N, Azrib R, González FJN, Brizgys L, McLean A.Serum amyloid A (SAA) is an acute phase protein and α-globulin that is produced in the liver in response to inflammatory cytokines. Considered a major acute phase protein in most domestic species, its concentrations rapidly decrease after resolution of inflammation, making SAA measurement a useful tool for monitoring the course of inflammation in an individual animal. The objective of this study was to compare SAA values in working equids including mules, donkeys and horses as well as values for different diseases at various times of the year. Samples were collected from 77 equids; 13 mules, ...
Meta-analysis of the effects of lidocaine on postoperative reflux in the horse.
Veterinary surgery : VS    July 9, 2019   Volume 49, Issue 1 44-52 doi: 10.1111/vsu.13286
Durket E, Gillen A, Kottwitz J, Munsterman A.To determine the efficacy of lidocaine at reducing incidence of postoperative reflux (POR) in horses by using quantitative statistical analysis. Methods: Systematic meta-analytical review. Methods: Studies on horses undergoing gastrointestinal surgery for small intestinal lesions, identified by systematic search between 2001 and 2017. Methods: A search with PubMed/MEDLINE, Web of Science, and Google Scholar was performed, followed by secondary searches of veterinary trade journals and bibliographies of relevant articles. The primary outcome measure for this study was the effect of lidocaine th...
And Now for Something Completely Different: Some Controversies in Equine Medicine, Surgery, and Reproduction.
The Veterinary clinics of North America. Equine practice    July 8, 2019   Volume 35, Issue 2 xi-xii doi: 10.1016/j.cveq.2019.05.001
MacKay RJ.No abstract available
Molecular detection of Streptococcus equi subspecies equi in face flies (Musca autumnalis) collected during a strangles outbreak on a Thoroughbred farm.
Medical and veterinary entomology    July 7, 2019   Volume 34, Issue 1 120-122 doi: 10.1111/mve.12394
Pusterla N, Bowers J, Barnum S, Hall JA.The objective of this study was to detect Streptococcus equi subspecies equi (S. equi) (Lactobacillales: Streptococcaceae) using quantitative polymerase chain reaction (qPCR) in flies collected from a farm with a documented outbreak of strangles. A total of 1856 face flies [Musca autumnalis (Diptera: Muscidae)] were collected using conventional fly traps. The flies were processed for nucleic acid purification and tested for the presence of S. equi by qPCR. A total of 10/1856 flies (0.54%) tested qPCR-positive for S. equi. The results may implicate the presence of face flies as a risk factor...
Evaluation of a Novel Bone Substitute Injection Technique for Potential Treatment of Impact Injury to the Equine Palmar Metacarpal Condyle.
Veterinary and comparative orthopaedics and traumatology : V.C.O.T    July 6, 2019   Volume 32, Issue 6 447-453 doi: 10.1055/s-0039-1692984
Rice HC, Brokken MT, Hostnik ET, Bertone AL. The aim of this study was to evaluate the injection of a bone substitute material (BSM) into an impact lesion in the palmar condyle of the third metacarpal bone. Methods:  This was an controlled study performed on six horses. Methods:  Medial metacarpal condyles were exposed via arthrotomy and a compressive lesion created in anaesthetized horses using 80 psi (27.6 MPa) onto the articular surface ( = 12). Paired limbs were randomly selected as a control or for extra-articular injection of BSM towards the subchondral bone near the compressive lesion. Parameters of the surgical tech...
Experimentally Induced Open Pneumothorax in Horses.
Journal of equine veterinary science    July 5, 2019   Volume 80 90-97 doi: 10.1016/j.jevs.2019.06.011
Canola PA, Valadão CAA, Canola JC, Flôres FN, Lopes MCS.The objective of this study was to evaluate clinical and cardiovascular parameters and pleural and intra-abdominal pressures of horses after experimentally induced unilateral open pneumothorax. Prospective, experimental study-animals: seven healthy adult horses, 4 females and 3 males. Left hemithorax thoracotomy was carried out to create an open pneumothorax for 60 minutes. Pleural pressure (P) was directly obtained at the midpoint of the left eighth intercostal space before thoracotomy. Esophageal pressure (P), arterial blood gas analysis, left ventricular function, and ultrasonographic asses...
Isolation of an Equine Foamy Virus and Sero-Epidemiology of the Viral Infection in Horses in Japan.
Viruses    July 5, 2019   Volume 11, Issue 7 613 doi: 10.3390/v11070613
Kirisawa R, Toishi Y, Hashimoto H, Tsunoda N.An equine foamy virus (EFV) was isolated for the first time in Japan from peripheral blood mononuclear cells of a broodmare that showed wobbler syndrome after surgery for intestinal volvulus and the isolate was designated as EFVeca_LM. Complete nucleotide sequences of EFVeca_LM were determined. Nucleotide sequence analysis of the long terminal repeat (LTR) region, and genes revealed that EFVeca_LM and the EFV reference strain had 97.2% to 99.1% identities. For a sero-epidemiological survey, indirect immunofluorescent antibody tests were carried out using EFVeca_LM-infected cells as an antige...
Polyphasic Discrimination of Trichophyton tonsurans and T. equinum from Humans and Horses.
Mycopathologia    July 5, 2019   Volume 185, Issue 1 113-122 doi: 10.1007/s11046-019-00344-9
Kandemir H, Dukik K, Hagen F, Ilkit M, Gräser Y, de Hoog GS.The anthropophilic dermatophyte Trichophyton tonsurans and its zoophilic counterpart T. equinum are phylogenetically closely related. The barcoding marker rDNA internal transcribed spacer (ITS) shows limited variation between these two species. In the current study, we combined molecular approaches with phenotypic data to determine the species boundaries between T. tonsurans (n = 52) and T. equinum (n = 15) strains originating from humans (n = 40), horses (n = 26), and a mouse (n = 1). Culture characteristics and physiology on Trichophyton agar media 1 and 5 were evaluated....
First Molecular Detection and Phylogenetic Analyses of Zoonotic Giardia intestinalis in Horses in Turkey.
Journal of equine veterinary science    July 4, 2019   Volume 80 56-60 doi: 10.1016/j.jevs.2019.06.017
Demircan K, Onder Z, Duzlu O, Yildirim A, Okur M, Ciloglu A, Yetismis G, Inci A.The goal of our study was to investigate the molecular prevalence of Giardia intestinalis in naturally infected horses in Kayseri, Central Anatolia Region in Turkey, to determine the molecular characterization of the obtained isolates and to exhibit the potential role of horses in zoonotic transmission of G. intestinalis. Fecal samples were randomly collected from totally 150 horses with clinically healthy between March and June of 2018. After the genomic DNA extractions, 25 (16.6%) of the 150 fecal samples, were found positive for G. intestinalis by nested PCR analyses of β-giardin gene. P...
Standing MRI for surgical planning of equine fracture repair.
Veterinary surgery : VS    July 3, 2019   Volume 48, Issue 8 1372-1381 doi: 10.1111/vsu.13272
Genton M, Vila T, Olive J, Rossignol F.To report the feasibility of standing MRI (sMRI) and document the value of sMRI in surgical planning for surgical repair of limb fractures in the horse. Methods: Retrospective case series. Methods: Thirty-one horses with preoperative sMRI. Methods: Medical records were reviewed for fracture type, application of a polyester cast, sMRI sequences performed, technical variables, and image quality. Fracture geometry and concomitant lesions were compared between sMRI and radiography. The relative value of sMRI with regard to surgical planning was classified as minor (sMRI did not provide additional ...
Surgical corrections and postsurgical complications of epiglottic entrapment in Thoroughbreds: 12 cases (2009-2015).
Journal of equine science    July 3, 2019   Volume 30, Issue 2 41-45 doi: 10.1294/jes.30.41
Lee SK, Lee I.Twelve Thoroughbred racehorses were diagnosed as epiglottic entrapment at the Korea Racing Authority equine hospital. Four different surgical correction techniques were used to treat epiglottic entrapment: the transnasal hook bistoury, transoral unshielded hook bistoury, transnasal shielded hook bistoury, and transendoscopic laser techniques. Eleven cases were surgically resolved eventually, with one case of recurrence. Five complications related to surgical correction occurred: a severe nasal passage laceration and bleeding (n=1), epiglottic laceration (n=1), epiglottis tip burns (n=2), and m...
Chronic equine hepacivirus infection in an adult gelding with severe hepatopathy.
Veterinary medicine and science    July 3, 2019   Volume 5, Issue 3 372-378 doi: 10.1002/vms3.181
Tegtmeyer B, Echelmeyer J, Pfankuche VM, Puff C, Todt D, Fischer N, Durham A, Feige K, Baumgärtner W, Steinmann E, Cavalleri JV.Equine hepacivirus (EqHV) in equids represents the closest homologue to hepatitis C virus (HCV) infecting humans. A majority of HCV infected patients develop a chronic course of infection leading to liver fibrosis, cirrhosis and liver failure. However, in horses mostly transient mild subclinical infections are reported for EqHV to date. EqHV can be involved in chronic liver diseases of horses. Biochemical parameters in serum samples were measured. Viral load was determined using qPCR. Next generation sequencing (NGS) of serum was performed. Liver tissue was stained with haematoxylin and eosin ...
Prevalence of post-race exertional heat illness in Thoroughbred racehorses and climate conditions at racecourses in Japan.
Journal of equine science    July 3, 2019   Volume 30, Issue 2 17-23 doi: 10.1294/jes.30.17
Nomura M, Shiose T, Ishikawa Y, Mizobe F, Sakai S, Kusano K.Despite growing recognition of post-race exertional heat illness (EHI) in the horse racing industry, reports on its prevalence are limited. The purpose of this study was to investigate the prevalence of post-race EHI and climate conditions at racecourses in Japan. The overall prevalence of EHI from 1999 to 2018 was 0.04% (387 cases for 975,247 starters) in races operated by the Japan Racing Association (JRA). The yearly prevalence has been increasing, exceeding 0.07% in the last four years of the studied period. The overall prevalence in summer (May-September) was 0.086% (352 cases for 409,908...
Pressuring of Acupoints as a Complement to the Diagnosis of Stifle Diseases in Horses.
Journal of acupuncture and meridian studies    July 2, 2019   Volume 12, Issue 5 151-159 doi: 10.1016/j.jams.2019.06.001
Mariani LPR, Sampaio F, Silveira AB, Bastos LF, Weber SH, Michelotto PV.Diseases of the stifle joint remain a challenge for veterinarians. The objective of this study was to achieve a valuable acupuncture suggestive diagnosis to be considered for stifle joint diseases in horses. Thirty-nine nonlame horses involved in different activities were assessed. Acupuncture was independently performed by two evaluators. Reactions of the animal when pressurizing the point suggestive of stifle disease (PSSD), Bladder-20 and/or Bladder-21, were considered as the inclusion criteria for inclusion in the stifle group (SG, n = 31), and the animals with no reactions were assigne...
Pathology in Practice.
Journal of the American Veterinary Medical Association    July 2, 2019   Volume 255, Issue 2 173-176 doi: 10.2460/javma.255.2.173
Bertram CA, Ertelt A, Lübke-Becker A, Erickson NA, Kershaw O.No abstract available
Surgical Repair of an Occipital Meningocele in a Foal.
Journal of equine veterinary science    July 2, 2019   Volume 81 102771 doi: 10.1016/j.jevs.2019.06.010
Alonso JM, Filho PTH, Ávila AR, Machado VMV, Hataka A, Bueno LMC, Alves ALG, Hussni CA, Rodrigues CA, Watanabe MJ.There are no previous reports of cranial meningocele in horses. In this report, we present the case of a 1-day-old male Quarter Horse that was born with a mass in the occipital region. The newborn was brought to the veterinary hospital, and a meningocele was diagnosed. The patient then underwent surgical closure of the defect. After an initial favorable response, the patient displayed signs of infection. The antibiotic therapy was changed, and the patient's condition improved. On the 13th postoperative day, the patient exhibited ataxia, difficulty standing, and limb hypertonia. Hydrocephalus w...
T2* and quantitative susceptibility mapping in an equine model of post-traumatic osteoarthritis: assessment of mechanical and structural properties of articular cartilage.
Osteoarthritis and cartilage    July 2, 2019   Volume 27, Issue 10 1481-1490 doi: 10.1016/j.joca.2019.06.009
Nykänen O, Sarin JK, Ketola JH, Leskinen H, Te Moller NCR, Tiitu V, Mancini IAD, Visser J, Brommer H, van Weeren PR, Malda J, Töyräs J, Nissi MJ.To investigate the potential of quantitative susceptibility mapping (QSM) and T2* relaxation time mapping to determine mechanical and structural properties of articular cartilage via univariate and multivariate analysis. Samples were obtained from a cartilage repair study, in which surgically induced full-thickness chondral defects in the stifle joints of seven Shetland ponies caused post-traumatic osteoarthritis (14 samples). Control samples were collected from non-operated joints of three animals (6 samples). Magnetic resonance imaging (MRI) was performed at 9.4 T, using a 3-D multi-echo gr...
Highlights of recent clinically relevant papers.
Equine veterinary education    July 1, 2019   Volume 31, Issue 8 394-395 doi: 10.1111/eve.13139
Wright S.No abstract available
Equine viral arteritis: not just a reproductive disease.
The Veterinary record    June 30, 2019   Volume 184, Issue 26 791-793 doi: 10.1136/vr.l4437
Following the recent confirmation of cases of equine viral arteritis in stallions in south-west England, James Crabtree of Equine Reproductive Services (UK) discusses the disease and its potential routes of spread into and around the UK.
Effect of proinflammatory cytokines on endometrial collagen and metallopeptidase expression during the course of equine endometrosis.
Cytokine    June 29, 2019   Volume 123 154767 doi: 10.1016/j.cyto.2019.154767
Szóstek-Mioduchowska AZ, Baclawska A, Okuda K, Skarzynski DJ.Equine endometrosis (endometrial fibrosis) is a degenerative chronic process that occurs in the uterus of the mare and disturbs proper endometrial function. Fibrosis is attributed to excessive deposition of extracellular matrix (ECM) components. The turnover of ECM is mediated by matrix metallopeptidases (MMP). Previously, it was shown that cytokines modulate MMP expression in other tissues and may regulate fibrosis indirectly by attracting inflammatory cells to the site of inflammation and directly on various tissues. However, the regulation of MMP expression in equine endometrosis is still r...