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Topic:Disease Management

Disease management in horses encompasses the strategies and practices employed to prevent, control, and treat diseases affecting equine populations. This field involves understanding the etiology, transmission, and clinical presentation of various equine diseases, as well as implementing biosecurity measures and therapeutic interventions. Common diseases in horses include equine influenza, strangles, and equine herpesvirus. Effective disease management relies on accurate diagnosis, vaccination protocols, and the use of antimicrobials and other treatments. This page compiles peer-reviewed research studies and scholarly articles that explore the methodologies, challenges, and advancements in managing diseases in equine health.
Therapy of Non-Dermatophytic Mycoses in Animals.
Journal of fungi (Basel, Switzerland)    October 30, 2018   Volume 4, Issue 4 doi: 10.3390/jof4040120
Elad D.This review focuses on aspects of antimycotic therapy specific to veterinary medicine. In the first part, drug availability, limited mostly by economic consideration but also by clinical applicability and specific adverse effects, is described for polyenes, 5 fluorocytosine, azoles, echinocandins and terbinafine. In the second part, current knowledge and experience in the treatment of selected fungal infections are overviewed. These mycoses include disseminated mold infections in small animals (dogs and cats) and avian species, upper respiratory tract infections of small animals (sino-nasal an...
Diagnosing and treating laminitis in horses.
The Veterinary record    October 27, 2018   Volume 183, Issue 16 505-506 doi: 10.1136/vr.k4485
Menzies-Gow N.No abstract available
Can heart rate variability parameters derived by a heart rate monitor differentiate between atrial fibrillation and sinus rhythm?
BMC veterinary research    October 25, 2018   Volume 14, Issue 1 320 doi: 10.1186/s12917-018-1650-6
Broux B, De Clercq D, Vera L, Ven S, Deprez P, Decloedt A, van Loon G.Heart rate variability (HRV) parameters, and especially RMSSD (root mean squared successive differences in RR interval), could distinguish atrial fibrillation (AF) from sinus rhythm(SR) in horses, as was demonstrated in a previous study. If heart rate monitors (HRM) automatically calculating RMSSD could also distinguish AF from SR, they would be useful for the monitoring of AF recurrence. The objective of the study was to assess whether RMSSD values obtained from a HRM can differentiate AF from SR in horses. Furthermore, the impact of artifact correction algorithms, integrated in the analyses ...
Equine parvovirus: An emerging equine health concern.
Equine veterinary journal    October 23, 2018   Volume 51, Issue 1 138 doi: 10.1111/evj.13025
Ou J, Lu G, Zhang G, Li S.No abstract available
Choosing the Best Approach to Wound Management and Closure.
The Veterinary clinics of North America. Equine practice    October 17, 2018   Volume 34, Issue 3 499-509 doi: 10.1016/j.cveq.2018.07.005
Kamus L, Theoret C.This article aims to help the practitioner by providing the tools to decide which type of closure or healing is best in a given situation. An overview of the main criteria and the different approaches to wound closure is presented. Each wound must be considered as a unique problem that requires a clinician to take into account all of its characteristics and limits to determine the best management approach.
Validation of a new experimental model for assessing drug efficacy against infection with Trypanosoma equiperdum in horses.
Veterinary parasitology    October 9, 2018   Volume 263 27-33 doi: 10.1016/j.vetpar.2018.10.005
Hébert L, Guitton E, Madeline A, Géraud T, Carnicer D, Lakhdar L, Pitel PH, Coste M, Laloy E, Giraudet A, Zientara S, Büscher P, Laugier C, Hans A....Trypanosoma equiperdum, the causative agent of dourine, may affect the central nervous system, leading to neurological signs in infected horses. This location protects the parasite from most (if not all) existing chemotherapies. In this context, the OIE terrestrial code considers dourine as a non-treatable disease and imposes a stamping-out policy for affected animals before a country may achieve its dourine-free status. The use of practices as drastic as euthanasia remains controversial, but the lack of a suitable tool for studying a treatment's efficacy against dourine hampers the developmen...
Celebrating excellence in equine medicine.
The Veterinary record    October 6, 2018   Volume 183, Issue 13 400 doi: 10.1136/vr.k4178
No abstract available
Identification of loci affecting sexually dimorphic patterns for height and recurrent laryngeal neuropathy risk in American Belgian Draft Horses.
Physiological genomics    September 28, 2018   Volume 50, Issue 12 1051-1058 doi: 10.1152/physiolgenomics.00068.2018
Brooks SA, Stick J, Braman A, Palermo K, Robinson NE, Ainsworth DM.Equine recurrent laryngeal neuropathy (RLN) is a bilateral mononeuropathy with an unknown etiology. In Thoroughbreds (TB), we previously demonstrated that the haplotype association for height (LCORL/NCAPG locus on ECA3, which affects body size) and RLN was coincident. In the present study, we performed a genome-wide association scan (GWAS) for RLN in 458 American Belgian Draft Horses, a breed fixed for the LCORL/NCAPG risk alelle. In this breed, RLN risk is associated with sexually dimorphic differences in height, and we identified a novel locus contributing to height in a sex-specific manner:...
Is there a future for ‘specials’ in equine practice?
The Veterinary record    September 22, 2018   Volume 183, Issue 11 338 doi: 10.1136/vr.k3984
No abstract available
Conservative versus surgical treatment of 21 sports horses with osseous trauma in the proximal phalangeal sagittal groove diagnosed by low-field MRI.
Veterinary surgery : VS    September 14, 2018   Volume 47, Issue 7 908-915 doi: 10.1111/vsu.12936
Lipreri G, Bladon BM, Giorio ME, Singer ER.To compare the outcome following conservative vs surgical management of sports horses with a diagnosis of subchondral bone trauma of the proximal aspect of the proximal phalanx (PP) by low-field MRI. Methods: Retrospective case series. Methods: Twenty-one mature sports horses with evidence of high water signal within the proximal sagittal groove of the PP according to low-field MRI of the fetlock, with no definitive radiographic evidence of fracture. Methods: Medical records (2010-2017) of horses admitted to 2 referral hospitals were reviewed. Historical, clinical, radiographic, and MRI findin...
Concussion History, Reporting Behaviors, Attitudes, and Knowledge in Jockeys.
Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine    September 14, 2018   Volume 30, Issue 6 578-584 doi: 10.1097/JSM.0000000000000658
O'Connor S, Warrington G, Whelan G, McGoldrick A, Cullen S.To examine concussion history, knowledge, and attitudes among Irish professional and amateur jockeys. Cross-sectional survey. Questionnaire was distributed through e-mails sent to all licensed jockeys, over social media and during professional and amateur race meetings. An average of 23.6% (12%-44%) Irish professional and amateur jockeys (n = 119) holding a license in 2017. Jockeys reported their previous concussion history, actions after their most recent concussion and responded to questions examining their knowledge and attitudes toward concussion. Amateur (32.4%) and professional (19.6%) j...
Antimicrobial resistance in bacteria isolated from horses from the Atlantic Provinces, Canada (1994 to 2013).
The Canadian veterinary journal = La revue veterinaire canadienne    September 11, 2018   Volume 59, Issue 9 951-957 
Awosile BB, Heider LC, Saab ME, McClure JT.This study determined the antimicrobial susceptibility patterns and trends for selected bacteria isolated from horses using diagnostic data from the Atlantic Veterinary College Diagnostic Services Bacteriology Laboratory, Charlottetown, Prince Edward Island over a 20-year period. subsp. and were the most commonly isolated bacteria over the study period. Clinical samples were most frequently submitted from respiratory and reproductive systems. Most bacterial isolates were susceptible to ceftiofur. Resistance was most common in Gram-negative enteric bacteria, while streptococci were frequentl...
Equine disease surveillance: quarterly summary.
The Veterinary record    September 9, 2018   Volume 183, Issue 9 289-292 doi: 10.1136/vr.k3819
No abstract available
Equine degenerative myeloencephalopathy: prevalence, impact, and management.
Veterinary medicine (Auckland, N.Z.)    September 7, 2018   Volume 9 63-67 doi: 10.2147/VMRR.S148542
Burns EN, Finno CJ.Equine neuroaxonal dystrophy/equine degenerative myeloencephalopathy is an inherited neurodegenerative disorder affecting many horse breeds. Clinical signs include a symmetric ataxia and an abnormal stance at rest, similar to cervical vertebral compressive myelopathy, equine protozoal myeloencephalitis, and equine herpesvirus 1 myeloencephalopathy. This review will provide an update on the disease prevalence, management, impact, and ongoing research.
Development of an indirect ELISA for the serological diagnosis of dourine.
Veterinary parasitology    September 4, 2018   Volume 261 86-90 doi: 10.1016/j.vetpar.2018.08.014
Dourine is a parasitic venereal disease of equines caused by T. equiperdum. Humoral antibodies are found in infected animals, but diagnosis of dourine must include history, clinical, and pathological findings in addition to serology. Complement Fixation Test (CFT) is the Office International des Epizooties (OIE) recommended test for international trade; however, some uninfected equines may give inconsistent or nonspecific reactions in CFT due to the anticomplementary effects of their sera. In this study an Indirect Enzyme Linked Immunosorbent Assay (iELISA) was developed. This test could be us...
Long-term management of horses with atopic dermatitis in southeastern England: a retrospective questionnaire study of owners’ perceptions.
Veterinary dermatology    September 3, 2018   Volume 29, Issue 6 526-e176 doi: 10.1111/vde.12685
Loeffler A, Herrick D, Allen S, Littlewood JD.Allergic pruritus and urticaria in the horse are challenging for veterinarians and owners; little is known about their long-term management. Objective: To summarize intradermal allergen test results (IDT), and to assess owners' perceptions of skin disease and the effects of medical treatment and management changes in their atopic horses over time. Methods: Eighty two horses with atopic dermatitis in southeastern England between 2006 and 2011. Methods: The IDT results were reviewed retrospectively. Owners completed telephone questionnaires on skin changes, medication, effect of allergen-specifi...
The clinical diagnosis of equine sarcoids-Part 2: Assessment of case features typical of equine sarcoids and validation of a diagnostic protocol to guide equine clinicians in the diagnosis of equine sarcoids.
Veterinary journal (London, England : 1997)    September 1, 2018   Volume 240 14-18 doi: 10.1016/j.tvjl.2018.08.010
Haspeslagh M, Gerber V, Knottenbelt DC, Schüpbach G, Martens A, Koch C.Research has shown that the accuracy of the clinical diagnosis of equine sarcoids (ES) can be improved. Particularly, less experienced veterinarians are often mistaken in their clinical judgement despite a high level of diagnostic confidence. The aim of this study was to develop and assess the performance of a diagnostic protocol (DP) to improve diagnostic accuracy and identify diagnostically challenging cases. The design of the DP was based on typical clinical features of ES and its algorithm was optimised through repeated tests on clinical cases prior to validating its performance in a repre...
Molecular survey and genetic diversity of piroplasmids in equids from Midwestern Brazil. Schein FB, Maia MO, Witter R, Marcili A, Camargo LM, Dutra V, Nakazato L, Candido SL, Almeida EM, Oliveira ACS, Pacheco RC.We evaluated the distribution of piroplasmids in equids from the Mato Grosso state in Midwestern Brazil using molecular methods and the interspecific genetic diversity. For this, 1,624 blood samples of equids from 973 farms were examined by PCR, using primer pairs that amplify a fragment of the genes rap-1 and ema-1 of Babesia caballi and Theileria equi, respectively. For molecular characterization and phylogenetic studies, 13 and 60 sequences of the rap-1 and ema-1 genes, respectively, were used to build a dendogram using maximum parsimony. B. caballi and T. equi were detected in 4.11% and 28...
Recommendations from the Australian and New Zealand Equine Endocrine Group and the interpretation of plasma endogenous ACTH concentrations for the diagnosis of pituitary pars intermedia dysfunction (PPID).
Australian veterinary journal    August 29, 2018   Volume 96, Issue 9 317-318 doi: 10.1111/avj.12743
McGowan C.No abstract available
Evaluation of chromocystoscopy in the diagnosis of cystitis in female donkeys.
PloS one    August 29, 2018   Volume 13, Issue 8 e0202596 doi: 10.1371/journal.pone.0202596
Abd El Kader NA, Farghali HA, Abu-Seida AM, Salem NY, Khattab MS.Early detection of cystitis in equine is essential to improve the prognosis and outcome of therapy. However, the conventional white light endoscopy is not sufficiently accurate for this purpose. Hence, this study evaluated chromoendoscopy as a recent diagnostic tool for cystitis in female donkeys. For this purpose, 5 apparently normal donkeys (control group) and 5 female donkeys with cystitis (diseased group) were used. Physical and rectal examinations, urine analysis, white light cystoscopy, methylene blue-based chromoendoscopy and histopathology were performed in all animals. Turbid urine ex...
Management practices associated with strongylid parasite prevalence on horse farms in rural counties of Kentucky.
Veterinary parasitology, regional studies and reports    August 23, 2018   Volume 14 25-31 doi: 10.1016/j.vprsr.2018.08.002
Scare JA, Steuer AE, Gravatte HS, Kálmán C, Ramires L, Dias de Castro LL, Norris JK, Miller F, Camargo F, Lawyer A, De Pedro P, Jolly B, Nielsen MK.Anthelmintic resistance among cyathostomin parasites is a wide-spread problem. The parasite control guidelines written by the American Association of Equine Practitioners (AAEP) encourages the preservation of anthelmintic efficacy by reducing treatment frequency, using targeted deworming, and implementing environmental management practices. While there is knowledge regarding parasite management practices of affluent horse farms in the United States, surveys rarely explore the rural and underserved regions. The purpose of this study was to observe the management practices of horse farms in rura...
Acinetobacter in veterinary medicine, with an emphasis on Acinetobacter baumannii.
Journal of global antimicrobial resistance    August 23, 2018   Volume 16 59-71 doi: 10.1016/j.jgar.2018.08.011
van der Kolk JH, Endimiani A, Graubner C, Gerber V, Perreten V.Acinetobacter spp. are aerobic, rod-shaped, Gram-negative bacteria belonging to the Moraxellaceae family of the class Gammaproteobacteria and are considered ubiquitous organisms. Among them, Acinetobacter baumannii is the most clinically significant species with an extraordinary ability to accumulate antimicrobial resistance and to survive in the hospital environment. Recent reports indicate that A. baumannii has also evolved into a veterinary nosocomial pathogen. Although Acinetobacter spp. can be identified to species level using matrix-assisted laser desorption/ionisation time-of-flight mas...
Environmental stressors may cause equine herpesvirus reactivation in captive Grévy’s zebras (Equus grevyi).
PeerJ    August 22, 2018   Volume 6 e5422 doi: 10.7717/peerj.5422
Seeber PA, Quintard B, Sicks F, Dehnhard M, Greenwood AD, Franz M.Equine Herpesviruses (EHV) are common and often latent pathogens of equids which can cause fatalities when transmitted to non-equids. Stress and elevated glucocorticoids have been associated with EHV reactivation in domestic horses, but little is known about the correlation between stress and viral reactivation in wild equids. We investigated the effect of an environmental stressor (social group restructuring following a translocation event) on EHV reactivation in captive Grévy's zebras (). A mare was translocated by road transport from Zoo Mulhouse, France, to join a resident group of three ...
Lower airway disease: Does research fit our practice needs?
Equine veterinary journal    August 18, 2018   Volume 50, Issue 5 701 doi: 10.1111/evj.12988
Kinnison T, Cardwell J, Smith K, Couëtil L, Wylie C, Whiting M, Roder C.No abstract available
Schmallenberg virus expands its geographical range in Northern Ireland.
The Veterinary record    July 22, 2018   Volume 183, Issue 3 88-91 doi: 10.1136/vr.k3177
No abstract available
Fifty years of recurring struggles with recurrent laryngeal neuropathy.
Equine veterinary journal    July 21, 2018   Volume 50, Issue 6 870 doi: 10.1111/evj.12981
Cook WR.No abstract available
Neurologic Conditions Affecting the Equine Athlete.
The Veterinary clinics of North America. Equine practice    July 17, 2018   Volume 34, Issue 2 277-297 doi: 10.1016/j.cveq.2018.04.006
Bedenice D, Johnson AL.EPM, CVSM, and EDM are currently recognized as the 3 most common neurologic diseases in US horses, with the latter 2 conditions being most prevalent in young animals. Moreover, horses competing at shows and performance events are at greater risk for exposure to highly contagious, neurologic EHV-1 outbreaks. A clinical diagnosis of any neurologic disease should be based on a careful history, complete neurologic examination, and appropriate diagnostic testing and interpretation. However, mild or early neurologic signs can often mimic or be mistaken for an orthopedic condition when horses present...
First report of anthelmintic resistance of equine cyathostomins in Cuba.
Veterinary parasitology, regional studies and reports    July 17, 2018   Volume 13 220-223 doi: 10.1016/j.vprsr.2018.07.005
Salas-Romero J, Gómez-Cabrera KA, Salas JE, Vázquez R, Arenal A, Nielsen MK.Anthelmintic resistance in equine cyathostomins has been described worldwide, with resistance to the benzimidazole class being particularly widespread. The status of anthelmintic efficacy in Cuba has been virtually unknown due to the lack of equine labelled products. One recent report documented suboptimal efficacy levels of extra-label albendazole products against cyathostomins, but it remains unknown to which extent benzimidazole resistance exists in the population. The aim of the present study was to evaluate the anthelmintic efficacy of two benzimidazole products labelled for equines, fenb...
What is your diagnosis? Bladder mass in a mare.
Veterinary clinical pathology    July 16, 2018   Volume 47, Issue 4 665-666 doi: 10.1111/vcp.12637
Fielder S, Breshears M.No abstract available
Identification of genetic variation in equine collagenous lectins using targeted resequencing.
Veterinary immunology and immunopathology    July 7, 2018   Volume 202 153-163 doi: 10.1016/j.vetimm.2018.07.001
Fraser RS, Arroyo LG, Meyer A, Lillie BN.Collagenous lectins are a family of soluble pattern recognition receptors that play an important role in innate immune resistance to infectious disease. Through recognition of carbohydrate motifs on the surface of pathogens, some collagenous lectins can activate the lectin pathway of complement, providing an effective means of host defense. Genetic polymorphisms in collagenous lectins have been shown in several species to predispose animals to a variety of infectious diseases. Infectious diseases are an important cause of morbidity in horses, however little is known regarding the role of equin...
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