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Topic:Disease Management

Disease management in horses encompasses the strategies and practices employed to prevent, control, and treat diseases affecting equine populations. This field involves understanding the etiology, transmission, and clinical presentation of various equine diseases, as well as implementing biosecurity measures and therapeutic interventions. Common diseases in horses include equine influenza, strangles, and equine herpesvirus. Effective disease management relies on accurate diagnosis, vaccination protocols, and the use of antimicrobials and other treatments. This page compiles peer-reviewed research studies and scholarly articles that explore the methodologies, challenges, and advancements in managing diseases in equine health.
Drugs for cardiovascular support in anesthetized horses.
The Veterinary clinics of North America. Equine practice    February 1, 2013   Volume 29, Issue 1 19-49 doi: 10.1016/j.cveq.2012.11.011
Schauvliege S, Gasthuys F.Despite the use of balanced anesthesia and fluids, drugs for cardiovascular support are often needed in anesthetized horses. Antimuscarinics can be used to treat bradycardia unrelated to hypertension. Vasopressors can be useful when hypotension is caused by vasodilation and/or when the effect of fluids and inotropes is insufficient. In most cases, however, inotropes, including sympathomimetics, calcium salts, and phosphodiesterase inhibitors, are preferred. Of the β-sympathomimetics, dobutamine remains the agent of choice. Calcium salts are mainly useful in hypocalcemic patients. Phosphodiest...
Oleander toxicosis in equids: 30 cases (1995-2010).
Journal of the American Veterinary Medical Association    February 1, 2013   Volume 242, Issue 4 540-549 doi: 10.2460/javma.242.4.540
Renier AC, Kass PH, Magdesian KG, Madigan JE, Aleman M, Pusterla N.To determine clinical, laboratory analysis, and necropsy findings for equids with oleander toxicosis and to identify factors associated with outcome. Methods: Retrospective case series. Methods: 30 equids. Methods: Medical records of equids with detectable concentrations of oleandrin in serum, plasma, urine, or gastrointestinal fluid samples and equids that had not received cardiac glycoside drugs but had detectable concentrations of digoxin in serum were identified via a medical records database search. Descriptive statistics were calculated for medical history, physical examination, laborato...
The history of arboviral infections of horses in Australia is being rewritten.
Australian veterinary journal    January 30, 2013   Volume 91, Issue 1-2 4 doi: 10.1111/avj.12030
Studdert MJ.No abstract available
Fungal diseases of horses.
Veterinary microbiology    January 29, 2013   Volume 167, Issue 1-2 215-234 doi: 10.1016/j.vetmic.2013.01.015
Cafarchia C, Figueredo LA, Otranto D.Among diseases of horses caused by fungi (=mycoses), dermatophytosis, cryptococcosis and aspergillosis are of particular concern, due their worldwide diffusion and, for some of them, zoonotic potential. Conversely, other mycoses such as subcutaneous (i.e., pythiosis and mycetoma) or deep mycoses (i.e., blastomycosis and coccidioidomycosis) are rare, and/or limited to restricted geographical areas. Generally, subcutaneous and deep mycoses are chronic and progressive diseases; clinical signs include extensive, painful lesions (not pathognomonic), which resemble to other microbial infections. In ...
Species’ life-history traits explain interspecific variation in reservoir competence: a possible mechanism underlying the dilution effect.
PloS one    January 24, 2013   Volume 8, Issue 1 e54341 doi: 10.1371/journal.pone.0054341
Huang ZY, de Boer WF, van Langevelde F, Olson V, Blackburn TM, Prins HH.Hosts species for multi-host pathogens show considerable variation in the species' reservoir competence, which is usually used to measure species' potential to maintain and transmit these pathogens. Although accumulating research has proposed a trade-off between life-history strategies and immune defences, only a few studies extended this to host species' reservoir competence. Using a phylogenetic comparative approach, we studied the relationships between some species' life-history traits and reservoir competence in three emerging infectious vector-borne disease systems, namely Lyme disease, W...
Longitudinal study of horses for carriage of methicillin-resistant Staphylococcus aureus following wound infections.
Veterinary microbiology    January 23, 2013   Volume 163, Issue 3-4 388-391 doi: 10.1016/j.vetmic.2013.01.004
Bergström K, Bengtsson B, Nyman A, Grönlund Andersson U.An outbreak of methicillin-resistant Staphylococcus aureus (MRSA) infections in horses in Sweden raised questions concerning the risk posed by horses to their surroundings following MRSA infections. This initiated a longitudinal study to investigate how long MRSA-infected horses remained positive and to test the sensitivity of different anatomical sampling sites for detection of MRSA. Between October 2008 and June 2010, 9 of 15 horses notified as having MRSA-infected wounds fitted the case criteria for the study. The cases were sampled at five anatomical sites (nostrils, corner of mouth, paste...
Australian plants show anthelmintic activity toward equine cyathostomins in vitro.
Veterinary parasitology    January 23, 2013   Volume 196, Issue 1-2 153-160 doi: 10.1016/j.vetpar.2013.01.012
Payne SE, Kotze AC, Durmic Z, Vercoe PE.Anthelmintic resistance in gastrointestinal parasites of horses is an increasing problem, particularly in cyathostomins, and there is a need to find alternative means for the control of these parasites. We screened crude extracts from 37 species of Australian native plants for their anthelmintic activity in vitro against cyathostomin larvae (development from egg to third larval stage), with the aim of identifying those species that may be suitable for incorporation into sustainable parasite management programs. Water extracts from seven species, namely Acacia baileyana, Acacia melanoxylon, Aca...
Equine sarcoidosis: clinical signs, diagnosis, treatment and outcome of 22 cases.
Veterinary dermatology    January 22, 2013   Volume 24, Issue 1 218-24.e48 doi: 10.1111/j.1365-3164.2012.01108.x
Sloet van Oldruitenborgh-Oosterbaan MM, Grinwis GC.Equine sarcoidosis may present as a generalized or localized exfoliative dermatitis and/or as a granulomatous inflammation of multiple organs. Objective: To report the clinical signs, diagnosis, treatment and outcome for 22 horses with histologically confirmed sarcoidosis. Methods: Twenty-two horses of different breeds, between 3 and 17 years of age. Methods: Diagnosis was based on clinical signs and histopathological findings. Results: The following three forms of equine sarcoidosis were identified: generalized (13.6%), partially generalized (18.2%) and localized (68.2%). High-dose systemic c...
Further evidence for better prevention of equine osteochondrosis.
The Veterinary record    January 22, 2013   Volume 172, Issue 3 66-67 doi: 10.1136/vr.f310
Robert C.No abstract available
Reining in equine metabolic syndrome: a gluttony of challenges.
Veterinary journal (London, England : 1997)    January 18, 2013   Volume 196, Issue 2 141-142 doi: 10.1016/j.tvjl.2012.12.014
de Laat MA.no abstract available
Anesthesia for the horse with colic.
The Veterinary clinics of North America. Equine practice    January 18, 2013   Volume 29, Issue 1 193-214 doi: 10.1016/j.cveq.2012.11.005
Boesch JM.This article discusses anesthesia for horses with colic from acute gastrointestinal disease. Emphasis is placed on new developments in pre-, intra-, and immediate postoperative management over the last decade, including early goal-directed therapy (EGDT) in the resuscitation of septic patients, the controversy over the optimal fluid type to administer, and the management of complications, such as cardiovascular depression, hypoventilation and hypoxemia, and decreased colloid oncotic pressure (COP). An update on analgesia is also provided; older drugs such as ketamine and lidocaine are increasi...
Equine disease surveillance: quarterly summary.
The Veterinary record    January 15, 2013   Volume 172, Issue 2 39-41 doi: 10.1136/vr.f61
Equine infectious anaemia in Europe Equine herpesvirus in the UK Summary of surveillance testing, July to September 2012 These are among matters discussed in the quarterly equine disease surveillance report for July to September 2012, prepared by Defra, the Animal Health Trust and the British Equine Veterinary Association.
The efficacy of rabbit antithymocyte globulin with cyclosporine in comparison to horse antithymocyte globulin as a first-line treatment in adult patients with severe aplastic anemia: a single-center retrospective study.
Annals of hematology    January 15, 2013   Volume 92, Issue 6 817-824 doi: 10.1007/s00277-013-1674-8
Shin SH, Yoon JH, Yahng SA, Lee SE, Cho BS, Eom KS, Kim YJ, Lee S, Min CK, Kim HJ, Cho SG, Kim DW, Min WS, Park CW, Lee JW.Antithymocyte globulin (ATG) is the drug of choice for immunosuppressive therapy (IST) in patients with severe aplastic anemia (SAA) ineligible for allogeneic stem cell transplantation. Recently, rabbit ATG with cyclosporine A has been used as a first-line IST regimen in patients with SAA because of unavailability of horse ATG. We retrospectively analyzed adult SAA patients who were treated with horse ATG (n=46) or rabbit ATG (n=53) between Feb 2001 and May 2010 to compare hematologic response and survival. Overall response rates at 3, 6, 12, and 18 months were similar in both the horse and ra...
Validated UHPLC-MS-MS method for rapid analysis of capsaicin and dihydrocapsaicin in equine plasma for doping control.
Journal of analytical toxicology    January 11, 2013   Volume 37, Issue 2 122-132 doi: 10.1093/jat/bks098
You Y, Uboh CE, Soma LR, Guan F, Taylor D, Li X, Liu Y, Chen J.A method involving ultra high-performance liquid chromatography-tandem mass spectrometry was developed and validated for the analysis of capsaicin and dihydrocapsaicin in equine plasma. The analytes were recovered from plasma by liquid-liquid extraction using methyl tert-butyl ether and separated on a sub-2 micron column. The mobile phase was composed of 2 mM ammonium formate and methanol. A triple quadrupole mass spectrometer was used to detect the analytes in positive electrospray ionization mode with selected reaction monitoring. The limits of detection, quantification and confirmation for ...
Evaluation of contact heat thermal threshold testing for standardized assessment of cutaneous nociception in horses – comparison of different locations and environmental conditions.
BMC veterinary research    January 8, 2013   Volume 9 4 doi: 10.1186/1746-6148-9-4
Poller C, Hopster K, Rohn K, Kästner SB.The aim of the study was to evaluate the performance of contact heat thermal stimulation in horses at different body sites and under different environmental conditions and different test situations. Five warm-blood horses were equipped with the thermal probe located on the skin of nostril (N), withers (W) or coronary band (C). Skin temperature and reaction temperature (thermal threshold) at each location were measured and percent thermal excursion (% TE = 100 * (threshold temperature - skin temperature)/(cut-out temperature - skin temperature) was calculated. Environmental conditions were ...
Effect of a stent bandage on the likelihood of incisional infection following exploratory coeliotomy for colic in horses: a comparative retrospective study.
Equine veterinary journal    January 7, 2013   Volume 45, Issue 5 564-569 doi: 10.1111/evj.12026
Tnibar A, Grubbe Lin K, Thurøe Nielsen K, Christophersen MT, Lindegaard C, Martinussen T, Ekstrøm CT.Incisional infections are common in horses after colic surgery. There is a clinical impression that the use of a stent bandage reduces the prevalence of such infections. Objective: To determine the effect of a stent bandage on the likelihood of incisional infection after ventral midline exploratory coeliotomy. It was hypothesised that the use of a stent bandage would reduce the likelihood of incisional infection. Methods: Medical records of horses that underwent exploratory coeliotomy for colic between January 2005 and September 2011 were reviewed. Inclusion criteria were animals that had one ...
The accuracy of the National Equine Database in relation to vector-borne disease risk modelling of horses in Great Britain.
Equine veterinary journal    January 7, 2013   Volume 45, Issue 3 302-308 doi: 10.1111/evj.12018
Robin CA, Lo Iacono G, Gubbins S, Wood JL, Newton JR.The National Equine Database (NED) contains information on the size and distribution of the horse population, but the data quality remains unknown. These data could assist with surveillance, research and contingency planning for equine infectious disease outbreaks. Objective: 1) To assess the extent of obsolete and missing data from NED, 2) evaluate the extent of spatial separation between horse and owner location and 3) identify relationships between spatial separation and land use. Methods: Two questionnaires were used to assess data accuracy in NED utilising local authority passport inspect...
Complications associated with cheek tooth extraction in the horse.
Journal of veterinary dentistry    January 1, 2013   Volume 30, Issue 4 220-235 doi: 10.1177/089875641303000404
Earley ET, Rawlinson JE, Baratt RM.Common indications for cheek tooth extraction in the horse include dental fracture, periodontal disease, severe decay/ caries, mandibular fracture with alveolar/tooth involvement, and periapical abscess. Complications secondary to extraction of cheek teeth are prevalent. Typical complications may include retained root tip(s), collateral damage of neighboring teeth and alveolar bone, mandibular fracture non-union or delayed union, cemental ankylosis, dilacerated root(s), oroantral/oronasal fistula, palatal deviation of cheek teeth, bone sequestration, sinus involvement, alveolar plug failure, a...
Comparison of a body-mounted inertial sensor system-based method with subjective evaluation for detection of lameness in horses.
American journal of veterinary research    December 29, 2012   Volume 74, Issue 1 17-24 doi: 10.2460/ajvr.74.1.17
Keegan KG, Wilson DA, Kramer J, Reed SK, Yonezawa Y, Maki H, Pai PF, Lopes MA.To compare data obtained with an inertial sensor system with results of subjective lameness examinations performed by 3 experienced equine veterinarians for evaluation of lameness in horses. Methods: 106 horses. Methods: Horses were evaluated for lameness with a body-mounted inertial sensor system during trotting in a straight line and via subjective evaluation by 3 experienced equine practitioners who performed complete lameness examinations including lunging in a circle and limb flexion tests. Agreement among evaluators regarding results of subjective evaluations and correlations and agreeme...
Controlling equine influenza: policy networks and decision-making during the 2007 Australian equine influenza outbreak.
Transboundary and emerging diseases    December 28, 2012   Volume 61, Issue 5 449-463 doi: 10.1111/tbed.12046
Schemann K, Gillespie JA, Toribio JA, Ward MP, Dhand NK.Rapid, evidence-based decision-making is critical during a disease outbreak response; however, compliance by stakeholders is necessary to ensure that such decisions are effective - especially if the response depends on voluntary action. This mixed method study evaluated technical policy decision-making processes during the 2007 outbreak of equine influenza in Australia by identifying and analysing the stakeholder network involved and the factors driving policy decision-making. The study started with a review of the outbreak literature and published policy documents. This identified six policy ...
Improving the diagnosis of equine colic.
The Veterinary record    December 25, 2012   Volume 171, Issue 25 636 doi: 10.1136/vr.e8562
No abstract available
Diagnosis of dourine in outbreaks in Italy.
Veterinary parasitology    December 20, 2012   Volume 193, Issue 1-3 30-38 doi: 10.1016/j.vetpar.2012.12.006
Pascucci I, Di Provvido A, Cammà C, Di Francesco G, Calistri P, Tittarelli M, Ferri N, Scacchia M, Caporale V.Dourine is trypanosomosis that affects equids, it's mainly sexually transmitted. The disease was first eradicated in Italy in the 1940s, but there was then a serious epidemic in the mid-70s. After sporadic reports at the end of the 1990s, in May 2011 it was reported once more. Clinical diagnosis of dourine can be complex, as clinical signs and gross lesions are not always present. Direct laboratory diagnosis is also problematic, given the low number of parasites normally present in infected tissues and the mild, short-lasting parasitaemia. This article describes the epidemiological, clinical a...
Lack of Cyathostomin sp. reduction after anthelmintic treatment in horses in Brazil.
Veterinary parasitology    December 20, 2012   Volume 194, Issue 1 35-39 doi: 10.1016/j.vetpar.2012.12.020
Canever RJ, Braga PR, Boeckh A, Grycajuck M, Bier D, Molento MB.The increase of anthelmintic resistance in the last years in the nematode population of veterinary importance has become a major concern. The objective of the present study was to evaluate the efficacy of the main anthelmintic drugs available in the market against small strongyles of horses in Brazil. A total of 498 horses from 11 horse farms, located in the states of Paraná, São Paulo, Rio de Janeiro and Minas Gerais, in Brazil, were treated with ivermectin, moxidectin, pyrantel and fenbendazole, orally at their recommended doses. The fecal egg count reduction test (FECRT) was used to deter...
Transmission of equine influenza virus during an outbreak is characterized by frequent mixed infections and loose transmission bottlenecks.
PLoS pathogens    December 20, 2012   Volume 8, Issue 12 e1003081 doi: 10.1371/journal.ppat.1003081
Hughes J, Allen RC, Baguelin M, Hampson K, Baillie GJ, Elton D, Newton JR, Kellam P, Wood JL, Holmes EC, Murcia PR.The ability of influenza A viruses (IAVs) to cross species barriers and evade host immunity is a major public health concern. Studies on the phylodynamics of IAVs across different scales - from the individual to the population - are essential for devising effective measures to predict, prevent or contain influenza emergence. Understanding how IAVs spread and evolve during outbreaks is critical for the management of epidemics. Reconstructing the transmission network during a single outbreak by sampling viral genetic data in time and space can generate insights about these processes. Here, we ob...
Tackling fly grazing in Wales.
The Veterinary record    December 19, 2012   Volume 171, Issue 24 608 doi: 10.1136/vr.e8397
No abstract available
Use of antibody titers measured via serum synergistic hemolysis inhibition testing to predict internal Corynebacterium pseudotuberculosis infection in horses.
Journal of the American Veterinary Medical Association    December 14, 2012   Volume 242, Issue 1 86-92 doi: 10.2460/javma.242.1.86
Jeske JM, Spier SJ, Whitcomb MB, Pusterla N, Gardner IA.To estimate likelihood ratios (LRs) of correctly identifying internal Corynebacterium pseudotuberculosis infection in horses by measurement of antibody titers via serum synergistic hemolysis inhibition (SHI) testing. Methods: Retrospective case-control study. Methods: 170 horses (171 records; 92 cases of C pseudotuberculosis infection and 79 controls). Methods: Medical records were reviewed, and horses were grouped on the basis of evidence of internal or external C pseudotuberculosis infection. The LRs and 95% confidence intervals for identification of internal C pseudotuberculosis infection b...
Reducing injuries in racehorses: mission impossible?
Equine veterinary journal    December 13, 2012   Volume 45, Issue 1 6-7 doi: 10.1111/evj.12009
Verheyen KL.No abstract available
Outbreaks of African horse sickness in Senegal, and methods of control of the 2007 epidemic.
The Veterinary record    December 7, 2012   Volume 172, Issue 6 152 doi: 10.1136/vr.101083
Diouf ND, Etter E, Lo MM, Lo M, Akakpo AJ.Since first being detected in Nigeria in January 2007, African horse sickness virus serotype 2 (AHSV-2) has spread throughout the northern hemisphere, and was first reported in Senegal. A retrospective study was conducted from December 2009 to April 2010 using data collected in the field combined with information available at the Direction of Veterinary Services. The epidemic started in the Dakar region with two outbreaks in March and June 2007, respectively, and spread in several parts of the country between July and November 2007. During this period, 232 outbreaks and 1137 horse deaths were ...
Medical management of sand enteropathy in 62 horses.
Equine veterinary journal    December 4, 2012   Volume 45, Issue 4 465-469 doi: 10.1111/evj.12014
Hart KA, Linnenkohl W, Mayer JR, House AM, Gold JR, Giguère S.Medical management of sand enteropathy is common in equine practice, but the clinical features and outcomes associated with medically managed sand enteropathy are not well described. Objective: To review clinical features, therapeutic approaches and outcomes associated with primary medical management of sand enteropathy in the mature horse. Methods: Medical record databases at 3 equine referral hospitals from January 2000 to April 2010 were reviewed for cases of sand enteropathy diagnosed via abdominal radiographs in mature horses that were initially managed medically. Data were collected and ...
A histological study of peripheral dental caries of equine cheek teeth.
Journal of veterinary dentistry    December 1, 2012   Volume 29, Issue 3 150-156 doi: 10.1177/089875641202900303
Erridge ME, Cox AL, Dixon PM.Peripheral caries of equine cheek teeth is a poorly described disorder and, in particular little is known of its histopathology. Histological examinations of decalcified sections of 21 equine peripheral caries-affected cheek teeth showed two different patterns of cemental lesions; including progressive enlargement of focal, flask-like lesions leading to breakdown of the adjacent cementum, and secondly; a more generalized flaking-off of thin layers of under-run, surface cementum. A thick layer of plaque and food material usually lay on the surface of affected cementum and also within cemental d...
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