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Topic:Disease

The study of diseases in horses encompasses a wide range of conditions affecting equine health, including infectious diseases, metabolic disorders, and genetic abnormalities. These diseases can impact various systems within the horse, such as respiratory, gastrointestinal, and musculoskeletal systems, and can lead to significant health challenges. Research in this area focuses on understanding the pathophysiology, diagnosis, prevention, and treatment of equine diseases. Common diseases studied include equine influenza, equine herpesvirus, and laminitis. This page provides access to peer-reviewed research studies and scholarly articles that explore the etiology, clinical presentation, and management strategies of diseases in horses, contributing to the advancement of equine veterinary medicine.
Rectal packing as initial management of grade 3 rectal tears.
Equine veterinary journal. Supplement    June 1, 1989   Issue 7 121-123 doi: 10.1111/j.2042-3306.1989.tb05670.x
Baird AN, Taylor TS, Watkins JP.Grade 3 rectal tears were created in 14 horses. Epidural anaesthesia was maintained in all horses for 8 h post injury. In seven horses with cotton filled stockinette packing the rectum, neither gross faecal contamination nor progression of the rectal tear occurred. Seven horses without rectal packing developed faecal contamination of the rectal tear with formation of a faeces filled serosal or mesorectal diverticulum.
DNA polymorphism analysis of hereditary multiple exostoses in horses.
American journal of veterinary research    June 1, 1989   Volume 50, Issue 6 978-983 
Li JK, Moloney BK, Shupe JL, Gardner EJ, Leone NC, Elsner Y.Genomic DNA polymorphisms obtained by restriction fragment-length polymorphism from healthy horses and horses with hereditary multiple exostoses were analyzed. These DNA were digested by 12 restriction enzymes and were hybridized against 6 isotopically labeled oncogene probes. Hybridization was not detected with the viral oncogene, v-ras, which indicated this oncogene was absent in the equine genome. Oncogenes (c-raf-1, c-fes, c-myb, c-myc, and c-sis) were present and had similar hybridization patterns and signal intensities in DNA from healthy horses and horses with hereditary multiple exosto...
Diagnostic aids for the detection of urine in the equine ejaculate.
Theriogenology    June 1, 1989   Volume 31, Issue 6 1141-1148 doi: 10.1016/0093-691x(89)90082-4
Althouse GC, Seager SW, Varner DD, Webb GW.An experiment was conducted to evaluate three commercially available test kits, the Azostix, Multistix and Uric-acid test, for the detection of urine in the equine ejaculate. Azostix, which tests for urea nitrogen, consistently detected urine in the equine ejaculate. Urine contamination was evident when a color change occurred in the reagent pad, going from yellow to green after 10 sec of exposure. The sensitivity of Azostix to urea nitrogen in contaminated samples was 39 mg/dl. The Multistix test kit also successfully detected urine in semen. In the Multistix nitrite pad the color changed fro...
The effect of Strongylus vulgaris larvae on equine intestinal myoelectrical activity.
Equine veterinary journal. Supplement    June 1, 1989   Issue 7 8-13 doi: 10.1111/j.2042-3306.1989.tb05646.x
Lester GD, Bolton JR, Cambridge H, Thurgate S.The myoelectrical activity of the ileum, caecum and large colon was monitored from Ag-AgCl bipolar recording electrodes in four conscious 'parasite-naive' weanling foals. All foals were inoculated with 1000 infective 3rd-stage Strongylus vulgaris larvae and alterations to the myoelectrical activity observed. The frequencies of caecal and colonic spike bursts increased significantly in all post infection periods coinciding with assumed larval penetration into the intestinal mucosa and migration through the vasculature. Peaks in caecal and colonic activity occurred at Days 1 to 5 post infection....
Atresia of the right atrioventricular orifice with complete transposition of the great arteries in a horse.
Anatomia, histologia, embryologia    June 1, 1989   Volume 18, Issue 2 177-182 doi: 10.1111/j.1439-0264.1989.tb00594.x
Zamora CS, Vitums A, Nyrop KA, Sande RD.The heart of a 6-week old Arabian filly with a history of poor health and exercise intolerance revealed at postmortem examination, multiple cardiac malformations which included atresia of the right atrioventricular orifice (tricuspid atresia, with associated atrial and ventricular septal defects), complete transposition of the great arteries, anomalous drainage of the venae cavae and coronary sinus into the left atrium, coarctation of the aorta, and a small but patent ductus arteriosus. The course of blood through the heart was suggested and discussed.
Plasma thromboxane B2 levels in horses experimentally infected with Strongylus vulgaris.
Equine veterinary journal. Supplement    June 1, 1989   Issue 7 14-18 doi: 10.1111/j.2042-3306.1989.tb05647.x
Cambridge H, Reynoldson JA, Dunsmore JD.Plasma thromboxane B2 (TXB2) the stable inactive metabolite of thromboxane A2 (TXA2), was measured daily by specific radioimmunoassay in three groups of animals before and after experimental infection with Strongylus vulgaris. Infection of four 'parasite naive' foals produced a typical acute syndrome with intermittent but statistically insignificant rises in TXB2 levels. Interpretation of results was complicated by the presence of a non-septic peritonitis associated with implantation of the foals with electrodes for recording myoelectrical activity. In two foals of similar age, with some natur...
Uterine clearance mechanisms during the early postovulatory period in mares.
American journal of veterinary research    June 1, 1989   Volume 50, Issue 6 864-867 
LeBlanc MM, Asbury AC, Lyle SK.Uterine response to inoculation with Streptococcus zooepidemicus organisms, 51Cr-labeled 15-microns microspheres, and charcoal was evaluated in 9 mares (4 resistant and 5 susceptible to endometritis) to determine mechanical and cellular clearance rates during the early postovulatory period. Mares were inoculated at estrus prior to ovulation during estrous cycles 1, 3, and 5. Uterine swab specimens for aerobic and anaerobic bacteriologic culture and serum for progesterone determination were obtained on postovulation day 3 during estrous cycle 1, on the day of ovulation during estrous cycle 3, a...
Comparison of detomidine, butorphanol, flunixin meglumine and xylazine in clinical cases of equine colic.
Equine veterinary journal. Supplement    June 1, 1989   Issue 7 111-116 doi: 10.1111/j.2042-3306.1989.tb05668.x
Jochle W, Moore JN, Brown J, Baker GJ, Lowe JE, Fubini S, Reeves MJ, Watkins JP, White NA.Detomidine hydrochloride, butorphanol tartrate, flunixin meglumine and xylazine hydrochloride were evaluated in a blind multi-centre clinical trial in 152 horses with abdominal pain. The drugs were administered as follows: detomidine 20 or 40 micrograms/kg bodyweight (bwt); butorphanol 0.1 mg/kg bwt; flunixin meglumine 1.0 mg/kg bwt; xylazine hydrochloride 0.5 mg/kg bwt. Each centre compared responses to the two doses of detomidine with those to one of the other analgesics. The drugs were administered intravenously (i.v.) after clinical assessment of the degree of sweating, kicking, pawing, he...
Development of an enzyme-linked immunosorbent assay for equine infectious anemia virus detection using recombinant Pr55gag.
Journal of clinical microbiology    June 1, 1989   Volume 27, Issue 6 1167-1173 doi: 10.1128/jcm.27.6.1167-1173.1989
Archambault D, Wang ZM, Lacal JC, Gazit A, Yaniv A, Dahlberg JE, Tronick SR.To provide more sensitive and convenient methods for the detection of equine infectious anemia virus (EIAV), we developed an enzyme-linked immunosorbent assay (ELISA) employing the EIAV gag precursor (Pr55gag) produced by using recombinant DNA techniques. The antigenic reactivity of the recombinant EIAV Pr55gag was found to be equivalent to that of the virion p24gag and elicited high-titered antiserum in rabbits. When a large number of horse sera were analyzed for the presence of antibodies to EIAV by this ELISA, a radioimmunoassay for EIAV p15gag, or the standard agar gel immunodiffusion test...
Resistance to gentamicin and amikacin of gram-negative organisms isolated from horses.
American journal of veterinary research    June 1, 1989   Volume 50, Issue 6 923-925 
Orsini JA, Benson CE, Spencer PA, Van Miller E.Resistance of gram-negative bacteria to gentamicin has become an increasingly common problem among clinical isolates from human beings. Susceptibility of isolates from horses to gentamicin and amikacin was evaluated for the period from July, 1983 to June, 1985. All isolates of Escherichia coli, and species of Enterobacter, Klebsiella, Proteus, and Pseudomonas examined were susceptible to amikacin, except 2 of the 46 Pseudomonas isolates. In contrast, 13 to 50% of isolates were resistant to gentamicin. Escherichia coli, and Klebsiella, Proteus, and Enterobacter species isolates were highly sign...
Benzimidazole resistance in a herd of horses.
The Veterinary record    May 27, 1989   Volume 124, Issue 21 560-561 doi: 10.1136/vr.124.21.560
Love S, McKellar QA, Duncan JL.No abstract available
Borrelia burgdorferi infection in horses.
Journal of the American Veterinary Medical Association    May 15, 1989   Volume 194, Issue 10 1384 
Lindenmayer J, Weber M, Onderdonk A.No abstract available
Unusual reaction following overdose of xylazine in a mare.
The Veterinary record    May 13, 1989   Volume 124, Issue 19 511 doi: 10.1136/vr.124.19.511-a
Groenendyk J, Hall LW.No abstract available
Equine herpesvirus.
The Veterinary record    May 13, 1989   Volume 124, Issue 19 519 doi: 10.1136/vr.124.19.519-a
No abstract available
Equine herpesvirus.
The Veterinary record    May 6, 1989   Volume 124, Issue 18 496 doi: 10.1136/vr.124.18.496
Collins A.No abstract available
Nephrolithiasis and ureterolithiasis in horses and their association with renal disease and failure.
Equine veterinary journal    May 1, 1989   Volume 21, Issue 3 161-162 doi: 10.1111/j.2042-3306.1989.tb02128.x
Divers TJ.No abstract available
Clinical, ultrasonographic and pathological findings in a horse with splenic lymphosarcoma and pseudohyperparathyroidism.
Equine veterinary journal    May 1, 1989   Volume 21, Issue 3 221-226 doi: 10.1111/j.2042-3306.1989.tb02152.x
Marr CM, Love S, Pirie HM.No abstract available
Experimental vaccinia virus infection of horses.
Australian veterinary journal    May 1, 1989   Volume 66, Issue 5 157-159 doi: 10.1111/j.1751-0813.1989.tb09788.x
Studdert MJ.No abstract available
Evolution of the ECG from Spanish bred foals during the post natal stage.
Research in veterinary science    May 1, 1989   Volume 46, Issue 3 358-362 
Tovar P, Escabias MI, Santisteban R.A study of electrocardiograms recorded from foals during the first two weeks of life has been made in order to detect any changes of the cardiac activation and recuperation processes during this period. A stepwise discriminant analysis revealed significant differences between the first and second week of age, fundamentally on the basis of the T and P wave amplitudes which gave the lowest values at 14 days, and on the PQ segment duration that showed the highest values at the same age.
Chronic renal failure associated with bilateral nephroliths and ureteroliths in a two-year-old Thoroughbred colt.
Equine veterinary journal    May 1, 1989   Volume 21, Issue 3 228-231 doi: 10.1111/j.2042-3306.1989.tb02154.x
Hope WD, Wilson JH, Hager DA, Garry MR, Calderwood-Mays MB.No abstract available
[A comparison of suturing and non-suturing of scrotal wounds following castration in stallions].
Tijdschrift voor diergeneeskunde    May 1, 1989   Volume 114, Issue 9 489-492 
Homburg-van den Broek FT, Rutgers LJ.It was found that wound infections may be considerably reduced when castration is carried out under strictly aseptic conditions. In this clinical review, healing of the wound following castration with and without closure of the scrotal wounds is compared. All castrations were performed under similar aseptic conditions, general anaesthesia having been produced in the recumbent stallion. The results do not show that there is a significant difference in the appearance of wound infections in scrotal wounds which are closed and those which are left completely open. On the basis of both papers and t...
Observations on the occurrence of five species of Gasterophilus larvae in free-ranging horses in Umbria, central Italy.
Veterinary parasitology    May 1, 1989   Volume 31, Issue 2 173-177 doi: 10.1016/0304-4017(89)90032-0
Principato M.Comparative data collected over 4 years show the most frequent species of Gasterophilus infesting free-ranging horses in Umbria (Central Italy) to be G. intestinalis (93.8%), G. nasalis (76.5%) and G. inermis (71%). G. pecorum and G. haemorrhoidalis were less frequent and appeared in 39.3 and 10.8% of the animals, respectively. For each of the 5 species, the duration of gastric and enteric lesions, the average numbers of larvae isolated throughout the year and the probable duration of oral lesions were discussed.
Pulmonary vascular reactivity of the newborn pony foal.
Equine veterinary journal    May 1, 1989   Volume 21, Issue 3 181-185 doi: 10.1111/j.2042-3306.1989.tb02137.x
Drummond WH, Sanchez IR, Kosch PC, Webb AI.Adult ponies develop pulmonary hypertension at altitude (Bisgard, Orr and Will 1975), but the neonatal response to acute hypoxaemia is unknown. Seven foals aged five days were instrumented with a systemic and a Swan-Ganz pulmonary artery catheter while anesthetised and intubated. Cardiac index, pulmonary (PAP) and systemic (SAP) vascular pressures were measured as the foals breathed gas mixtures with FI02 of 8 to 94 per cent. Because foramen ovale or ductus arteriosus shunts might have altered thermodilution cardiac index measurements in the stressed foals, the ratio, PAP/SAP was calculated to...
Osteomyelitis of the calcaneus in horses: 28 cases (1972-1987).
Journal of the American Veterinary Medical Association    May 1, 1989   Volume 194, Issue 9 1317-1323 
MacDonald MH, Honnas CM, Meagher DM.Medical records of 28 horses with osteomyelitis of the calcaneus were reviewed to evaluate signalment, history, diagnostic and treatment methods, outcome, and long-term follow-up information. Trauma was the most commonly reported cause (24). Physical examination revealed lameness in 27 horses, and 22 (79%) had a wound or draining tract over the plantar aspect of the calcaneus. Radiography of all horses was done prior to the initiation of treatment, and follow-up radiography was done on 20 horses. The most common radiographic findings were soft tissue swelling (25), bony lysis of the calcaneus ...
[The possibility of using equine serum albumin in place of bovine serum albumin and ovalbumin in radioimmunological and immunoenzyme analyses and in virological practice].
Zhurnal mikrobiologii, epidemiologii i immunobiologii    May 1, 1989   Issue 5 47-50 
Kolmakova MV, Kuskova ZR, Ratner GM, Laptakova LM.Horse serum albumin has been shown to meet the requirements to protein preparations for microanalysis and thus to be suitable for use in kits of reagents for the radioimmunological determination of insulin and myoglobin, for the determination of tick-borne encephalitis virus antigen by the method of the enzyme immunoassay and for the stabilization of proteins in the hemagglutination test and the hemagglutination inhibition test.
[The occurrence and significance of plasma coagulase negative staphylococci from the genital tract of horses].
DTW. Deutsche tierarztliche Wochenschrift    May 1, 1989   Volume 96, Issue 5 256-258 
Hüthwohl H, Weiss R, Schmeer N, Schliesser T.Classification based on biochemical characteristics of 389 strains of plasma-coagulase-negative (plc-) staphylococci isolated from the genital tract of mares and stallions resulted in the following distribution of species: St. sciuri 130 (33.4%), St. equorum 42 (10.8%), St. xylosus 16 (4.1%), St. epidermidis 35 (9.0%), St. simulans 24 (6.2%), St. haemolyticus 33 (8.5%), St. warneri 18 (4.6%), St. lentus 12 (3.1%), St. hyicus 11 (2.8%). Strains of St. cohnii, St. capitis, St. gallinarum, St. saprophyticus and St. hominis have only been found sporadically (a. 1%). 48 (12.3%) strains could not be...
Equine herpesvirus outbreaks.
The Veterinary record    April 29, 1989   Volume 124, Issue 17 471 doi: 10.1136/vr.124.17.471-d
Frank C.No abstract available
EHV-1: a recurrent problem.
The Veterinary record    April 29, 1989   Volume 124, Issue 17 443-444 doi: 10.1136/vr.124.17.443
No abstract available
Fragments of nasogastric tubes as esophageal foreign bodies in two horses.
Journal of the American Veterinary Medical Association    April 15, 1989   Volume 194, Issue 8 1068-1070 
Baird AN, True CK.Two horses were referred with fragments of nasogastric tubes as esophageal foreign bodies. Radiography and endoscopy were used to identify the location of the fragments. Portions of the tubes were retrieved by esophagotomy in 1 horse and by manual examination of the oral cavity in the other. Both tubes were friable in focal areas, but were quite pliable over most of the length of the tube.
Bilateral eyelid swelling attributable to lymphosarcoma in a horse.
Journal of the American Veterinary Medical Association    April 1, 1989   Volume 194, Issue 7 939-942 
Murphy CJ, Lavoie JP, Groff J, Hacker D, Pryor P, Bellhorn RW.Bilateral swelling of upper and lower eyelids was caused by lymphocytic infiltration in an 8-year-old Thoroughbred mare. The condition worsened with pregnancy and became associated with subcutaneous dissemination of lymphosarcoma at distant sites.