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Topic:Epidemiology

Epidemiology in horses involves the study of the distribution and determinants of health-related states and events in equine populations. It encompasses the investigation of patterns, causes, and effects of diseases and health conditions within horse populations. This field of study aims to identify risk factors for disease and targets for preventive healthcare. Key components of equine epidemiology include disease surveillance, outbreak investigation, and the study of disease dynamics within herds or regions. Research in this area often focuses on infectious diseases, zoonotic diseases, and the impact of environmental factors on equine health. This page compiles peer-reviewed research studies and scholarly articles that explore various aspects of epidemiology in horses, including disease prevalence, transmission pathways, and strategies for disease prevention and control.
[Molecular diagnostic of congenital babesiosis in neonates foals from State of Rio de Janeiro, Brazil]. Santos TM, Santos HA, Massard CL.The aim of this study was to demonstrate, through nested PCR (nPCR) method, the occurrence of congenital babesiosis in two foals born of carrier mares. All mares were positive for T. equi based in visualization of intraerytrocytic parasites in blood smears, in indirect fluorescent antibody test (IFAT) and nPCR reactions. Just one mare was nPCR-positive for B. caballi. After the birth, all foals presented nPCR-positive for T. equi, while just one foal presented nPCR-positive for B. caballi. The present study prove the occurrence of congenital babesiosis in new-born foals, however, new studies a...
[Seroepidemiological studies on Babesia equi in horses from the State of Rio Grande do Sul determined by indirect immunoflourecence test and Elisa]. Golynski AA, Fernandes KR, Baldani CD, Golynski AL, Madeiro AS, Machado RZ, Botteon Pde T, Massard CL.This research was performed to study the prevalence of antibodies against Babesia equi in horses of the northern region of Rio Grande do Sul state, using ELISA and indirect immunofluorescence antibody test (IFA). The total sera sample was 380, this number was considered as statistically representative of the population, as determined by mathematical model. The prevalence of B. equi was 31.6% and 35.8% by ELISA and IFA, respectively. The concordance between the assays was 0.87 (indices kappa), which is considered an optimal result. The results did not show any significant statistical difference...
[Quantitative prevalence of Anoplocephala sp. and egg shedding consistency in horses]. De Almeida JC, Augusto Mde M, Da Silva TG, De Toledo PS, De Souza DF, Antunes J, Molento MB.The objective of this work was to determine the quantitative prevalence of Anoplocephala sp. in thoroughbred horses raised in São José dos Pinhais, PR using the modified centrifugal-flotation technique. Repeatability values for the eggs per gram (EPG) were evaluated at 28-day intervals. The coproparasitological tests were made in 28 one-year old animals, 25 two-year old animals and 28 mares during the 2007 period of January 31st and June 15th. In the comparison of EPG, all mares presented low values than the foals (P = 0.04). The prevalence results indicated 50, 18 and 40% Anoplocephala sp. ...
Investigation of antigen specific lymphocyte responses in healthy horses vaccinated with an inactivated West Nile virus vaccine.
Veterinary immunology and immunopathology    August 30, 2008   Volume 126, Issue 3-4 293-301 doi: 10.1016/j.vetimm.2008.08.007
Davis EG, Zhang Y, Tuttle J, Hankins K, Wilkerson M.West Nile virus (WNV) is a single-stranded, enveloped RNA virus capable of causing encephalitic disease in horses. Unvaccinated horses are at risk for developing WNV disease in endemic geographic regions. Effective vaccination reduces disease frequency and diminishes disease severity in vaccinated individuals that become infected with WNV. Recent data indicate CD4+ lymphocytes are required for effective protection against disease; in particular, cross talk between CD4+ and CD8+ lymphocytes must be functional. The objective of this project was to investigate immune responses in horses throughou...
REVIEW paper: mare reproductive loss syndrome.
Veterinary pathology    August 30, 2008   Volume 45, Issue 5 710-722 doi: 10.1354/vp.45-5-710
Sebastian MM, Bernard WV, Riddle TW, Latimer CR, Fitzgerald TD, Harrison LR.An epidemic of early fetal loss (EFL), late fetal loss (LFL), fibrinous pericarditis, and unilateral uveitis which occurred during the spring of 2001, are together now known as the mare reproductive loss syndrome (MRLS). A similar epidemic with less intensity was reported during the same period of time from southern Ohio, West Virginia, and Tennessee. The same syndrome with lesser intensity recurred in 2002. The estimated economic loss from the syndrome in 2001 and 2002 together was approximately $500 million. Both EFL and LFL were characterized by the absence of specific clinical signs in abo...
Identification of equid herpesvirus-5 in respiratory liquids: a retrospective study of 785 samples taken in 2006-2007.
Veterinary journal (London, England : 1997)    August 30, 2008   Volume 182, Issue 2 346-348 doi: 10.1016/j.tvjl.2008.07.004
Fortier G, Pronost S, Miszczak F, Fortier C, Léon A, Richard E, Van Erck E, Thiry E, Lekeux P.During a case control study undertaken in 2006-2007, a screening and consensus polymerase chain reaction (PCR) was performed to evaluate the potential role of equid herpesviruses (EHV) in several occurrences of respiratory disorders in 661 horses. Of 785 bronchoalveolar or tracheal lavage fluid samples submitted for analysis, 20 were positive for EHV-5 DNA by sequential analysis of the consensus PCR product. Nineteen of those samples were confirmed using a specific EHV-5 PCR. No particular changes in cytological profile could be associated with the detection of EHV-5 in contrast to suggestions...
Arterial calcification in race horses.
Veterinary pathology    August 30, 2008   Volume 45, Issue 5 617-625 doi: 10.1354/vp.45-5-617
Arroyo LG, Hayes MA, Delay J, Rao C, Duncan B, Viel L.Calcification of large arteries has been sporadically reported in horses. The pathogenesis is still unknown, but recent studies in humans suggest that this is a regulated biomineralizing process. This study surveyed the prevalence, distribution, and severity of vascular calcification in Thoroughbred and Standardbred racehorses. Histopathologic, ultrastructural imaging, and energy dispersive X-ray elemental analyses were used to examine the lesions. Calcification of the tunica media, predominantly the pulmonary artery, was found in 82% of horses (83/101). Young adult horses (mean [SD] age in ye...
Public health use of surveillance for West Nile virus in horses: Saskatchewan, 2003-2005.
Transboundary and emerging diseases    August 27, 2008   Volume 55, Issue 9-10 411-416 doi: 10.1111/j.1865-1682.2008.01051.x
Epp T, Waldner C, Corrigan R, Curry P.West Nile virus (WNV) infection in horses was first reported in Canada in 2001 and in the province of Saskatchewan in 2002. This paper outlines the surveillance results of WNV in Saskatchewan horses from 2003 to 2005 and describes the usefulness of its inclusion in an integrated surveillance program in Saskatchewan. The number of human and horse cases was highest in 2003, the epidemic year and then substantially lower in 2004 and 2005. Horses provided additive information about WNV activity in rural areas with low human population, however, this required willingness and active participation by...
Serum antibodies to West Nile virus in naturally exposed and vaccinated horses.
Journal of medical microbiology    August 23, 2008   Volume 57, Issue Pt 9 1087-1093 doi: 10.1099/jmm.0.47849-0
Magnarelli LA, Bushmich SL, Anderson JF, Ledizet M, Koski RA.A polyvalent ELISA and plaque reduction neutralization tests (PRNTs) were used to measure serum antibodies to West Nile virus (WNV) in horses naturally exposed to or vaccinated against this flavivirus in Connecticut and New York State, USA. Relying on a PRNT as a 'gold standard', the main objective was to validate a modified ELISA containing a recombinant WNV envelope protein antigen. It was also important to assess specificity by testing sera from horses that had other, undiagnosed illnesses. Sera for the latter study were obtained from 43 privately owned horses during 1995-1996. Analyses by ...
Glanders.
Journal of the American Veterinary Medical Association    August 20, 2008   Volume 233, Issue 4 570-577 doi: 10.2460/javma.233.4.570
Dvorak GD, Spickler AR.No abstract available
Equine veterinary journal. Issue content.
Equine veterinary journal    August 16, 2008   Volume 40, Issue 5 430 doi: 10.2746/042516408x327431
Rossdale PD.No abstract available
Toxoplasmosis in livestock in Italy: an epidemiological update.
Parassitologia    August 13, 2008   Volume 50, Issue 1-2 59-61 
Infection with Toxoplasma gondii is one of the most common parasitic infections of human being and other warm-blooded animals. It has been found worldwide from Alaska to Australia. Public health organizations repeatedly encourage the collection of accurate data about T. gondii in animals and humans due to its medical importance as a major source of parasitic zoonosis. For these reasons, epidemiological updates on toxoplasmosis in livestock are strongly advised also to plan control strategies. In the present paper, seroprevalence data on T. gondii that have been recorded in livestock from diffe...
The demographics of equestrian-related injuries in the United States: injury patterns, orthopedic specific injuries, and avenues for injury prevention.
The Journal of trauma    August 13, 2008   Volume 65, Issue 2 447-460 doi: 10.1097/TA.0b013e31817dac43
Loder RT.It was the purpose of this study to review equestrian-related injuries using a large nation wide database and analyze predictors of significant injury. Methods: The National Electronic Surveillance System database was queried for equestrian injuries from 2002 to 2004. The presence of a fracture, dislocation, traumatic brain injury, musculoskeletal injury, orthopedic injury, and spinal injury, as well as injury mechanism, geographical location, and emergency room disposition were noted. Bivariate, cosinor seasonal, and multiple logistic regression analyses were performed. p < 0.01 was considere...
Analysis of horse-related injuries in children.
Pediatric surgery international    August 12, 2008   Volume 24, Issue 10 1165-1169 doi: 10.1007/s00383-008-2214-9
Kiss K, Swatek P, Lénárt I, Mayr J, Schmidt B, Pintér A, Höllwarth ME.The purpose of the present study was to investigate factors affecting the nature, characteristics, severity and outcome of horseback and horse care injuries in paediatric patients and to create guidelines for injury prevention. Methods: Detailed clinical records of 265 children sustained horse-riding related injuries have been analysed. Questionnaires were mailed to provide follow-up information for patients who have been treated in either Department of Paediatric Surgery in Pécs, Hungary, or Department of Paediatric Surgery in Graz, Austria between 1999 and 2003. Those 112 children (42%) who...
Isolation and analysis of the genetic diversity of repertoires of VSG expression site containing telomeres from Trypanosoma brucei gambiense, T. b. brucei and T. equiperdum.
BMC genomics    August 12, 2008   Volume 9 385 doi: 10.1186/1471-2164-9-385
Young R, Taylor JE, Kurioka A, Becker M, Louis EJ, Rudenko G.African trypanosomes (including Trypanosoma brucei) are unicellular parasites which multiply in the mammalian bloodstream. T. brucei has about twenty telomeric bloodstream form Variant Surface Glycoprotein (VSG) expression sites (BESs), of which one is expressed at a time in a mutually exclusive fashion. BESs are polycistronic transcription units, containing a variety of families of expression site associated genes (ESAGs) in addition to the telomeric VSG. These polymorphic ESAG families are thought to play a role in parasite-host adaptation, and it has been proposed that ESAG diversity might ...
Preliminary molecular identification of drug resistant cyathostomes in Italy.
Veterinary research communications    August 8, 2008   Volume 32 Suppl 1 S211-S213 doi: 10.1007/s11259-008-9156-5
Lia RP, Traversa D, Iorio R, Otranto D, Klei TR, Ricci V, Giangaspero A.No abstract available
A serological survey of African horse sickness in Botswana.
Journal of the South African Veterinary Association    August 6, 2008   Volume 79, Issue 1 44-45 doi: 10.4102/jsava.v79i1.240
Hyera JM, Baipoledi EK.A retrospective serological survey of African horse sickness (AHS) in Botswana covering a 10-year period (1995-2004) is reported. The survey involved horses showing clinical symptoms of the disease; the horses had not been vaccinated against AHS. Over the period surveyed, serological evidence suggestive of infection with AHS virus (AHSV) was found in 99 clinical cases out of which 41.4% (41/99) cases were found during the 1st half (1995-1999) and 58.6 % (58/99) cases were found in the 2nd half of the survey period (2000-2004). These serological findings are discussed in relation to AHSV seroty...
Detection of equine herpesvirus-1 in nasal swabs of horses by quantitative real-time PCR.
Journal of veterinary internal medicine    August 6, 2008   Volume 22, Issue 5 1234-1238 doi: 10.1111/j.1939-1676.2008.0172.x
Perkins GA, Goodman LB, Dubovi EJ, Kim SG, Osterrieder N.Early identification of inhalation-transmitted equine herpesvirus type 1 (EHV-1) infections has been facilitated by the availability of a number of real-time quantitative PCR (qPCR) tests. A direct comparison between nasal swab qPCR and traditional virus isolation (VI) requires a method for normalizing the qPCR samples and controlling for PCR inhibitors present in some clinical samples. Objective: To quantify EHV-1 shedding in viral swabs using an internal control and to compare fast qPCR to VI for the detection of EHV-1 in nasal swabs from horses. Methods: Fifteen horses experimentally infect...
Glycogen synthase 1 (GYS1) mutation in diverse breeds with polysaccharide storage myopathy.
Journal of veterinary internal medicine    August 6, 2008   Volume 22, Issue 5 1228-1233 doi: 10.1111/j.1939-1676.2008.0167.x
McCue ME, Valberg SJ, Lucio M, Mickelson JR.A missense mutation in the GYS1 gene was recently described in horses with polysaccharide storage myopathy (PSSM). Objective: The first objective was to determine the prevalence of the GYS1 mutation in horses with PSSM from diverse breeds. The second objective was to determine if the prevalence of the GYS1 mutation differed between horses diagnosed with PSSM based on grade 1 (typically amylase-sensitive) or grade 2 (typically amylase-resistant) polysaccharide. Methods: Eight hundred and thirty-one PSSM horses from 36 breeds. Methods: Horses with PSSM diagnosed by histopathology of skeletal mus...
Epidemiological survey on farms with documented occurrence of equine proliferative enteropathy due to Lawsonia intracellularis.
The Veterinary record    August 5, 2008   Volume 163, Issue 5 156-158 doi: 10.1136/vr.163.5.156
Pusterla N, Higgins JC, Smith P, Mapes S, Gebhart C.No abstract available
Macrocyclic lactone resistance in cyathostomins.
The Veterinary record    August 5, 2008   Volume 163, Issue 5 163-164 doi: 10.1136/vr.163.5.163-a
Dudeney A, Campbell C, Coles G.No abstract available
Plasma levels of zinc, copper, copper/zinc ratio, and activity of carbonic anhydrase in equine piroplasmosis.
Biological trace element research    August 3, 2008   Volume 125, Issue 1 41-45 doi: 10.1007/s12011-008-8136-5
Dede S, Değer Y, Değer S, Tanritanir P.We have determined the plasma concentrations of copper, zinc, copper/zinc ratio, and carbonic anhydrase activity in horses infected with Babesia equi. The study was conducted in 14 horses with the disease and 10 healthy animals that served as controls. The infection was confirmed by the clinical manifestations of the disease and by Giemsa staining of thin blood smears showing the parasites inside red blood cells. The horses with piroplasmosis had lower plasma levels of zinc, elevated copper, and increased activity of carbonic anhydrase. Consequently, the copper/zinc ratio was also higher than ...
Evaluation of the pathogenicity of African Horsesickness (AHS) isolates in vaccinated animals.
Vaccine    August 3, 2008   Volume 26, Issue 39 5014-5021 doi: 10.1016/j.vaccine.2008.07.037
von Teichman BF, Smit TK.The polyvalent African Horsesickness (AHS) attenuated live vaccine (ALV) produced by Onderstepoort Biological Products (OBP) Ltd., South Africa, has been associated with some safety concerns and alleged cases of vaccine failure or vaccine-induced disease. The risk of reassortment and reversion to virulence is a common concern associated with the use of ALVs, and a phenomenon reported for viruses with segmented RNA genomes. The purpose of this study was to determine whether or not reassortment of AHS vaccine strains could result in reassortants and reversion to virulence and therefore cause AHS...
Denatured virion protein 1 of equine rhinitis B virus 1 contains authentic B-cell epitopes recognised in an enzyme-linked immunosorbent assay–short communication.
Acta veterinaria Hungarica    August 2, 2008   Volume 56, Issue 2 265-270 doi: 10.1556/AVet.56.2008.2.14
Kriegshäuser G, Cullinane A, Kuechler E, Skern T.Equine rhinitis B virus 1 (ERBV1), genus Erbovirus, family Picornaviridae, is a pathogen of horses which causes clinical and subclinical infection of the upper respiratory tract in horses. The virus is widespread in European horse populations and the current standard method for the detection of antibody against ERBV1 is by virus neutralisation (VN). VN tests, however, are labour-intensive and time-consuming, require tissue culture facilities, and generally do not provide same-day results. In this study, a protocol for the high-level expression and purification of recombinant virion protein 1 (...
Equine disease surveillance. Equine disease surveillance, January to March 2008.
The Veterinary record    August 1, 2008   Volume 162, Issue 25 803-806 doi: 10.1136/vr.162.25.803
No abstract available
Report of the 3rd Havemeyer workshop on allergic diseases of the Horse, Hólar, Iceland, June 2007.
Veterinary immunology and immunopathology    July 31, 2008   Volume 126, Issue 3-4 351-361 doi: 10.1016/j.vetimm.2008.07.008
Marti E, Gerber V, Wilson AD, Lavoie JP, Horohov D, Crameri R, Lunn DP, Antczak D, Björnsdóttir S, Björnsdóttir TS, Cunningham F, Dérer M....Allergic diseases occur in most mammals, although some species such as humans, dogs and horses seem to be more prone to develop allergies than others. In horses, insect bite hypersensitivity (IBH), an allergic dermatitis caused by bites of midges, and recurrent airway obstruction (RAO), a hyperreactivity to stable born dust and allergens, are the two most prevalent allergic diseases. Allergic diseases involve the interaction of three major factors: (i) genetic constitution, (ii) exposure to allergens, and (iii) a dysregulation of the immune response determined by (i) and (ii). However, other e...
North American encephalitic arboviruses.
Neurologic clinics    July 29, 2008   Volume 26, Issue 3 727-ix doi: 10.1016/j.ncl.2008.03.012
Davis LE, Beckham JD, Tyler KL.Arboviruses continue to be a major cause of encephalitis in North America, and West Nile virus neuroinvasive disease is now the dominant cause of encephalitis. Transmission to humans of North American arboviruses occurs by infected mosquitoes or ticks. Most infections are asymptomatic or produce a flulike illness. Rapid serum or cerebrospinal fluid IgM antibody capture ELISA assays are available to diagnosis the acute infection for all North American arboviruses. Unfortunately, no antiviral drugs are approved for the treatment of arbovirus infection and current therapy is supportive.
Diagnostic equine serology.
The Veterinary clinics of North America. Equine practice    July 26, 2008   Volume 24, Issue 2 311-vi doi: 10.1016/j.cveq.2008.03.002
Zimmerman KL, Crisman MV.This article is presented with two main goals: (1) to provide equine clinicians with a resource for identifying types of serum tests available and (2) to outline briefly the necessary sample type, assay principle, and relative strengths and weakness of the various methods. Specific etiologies are presented and grouped by clinical diagnosis categories, along with brief comments concerning each disorder and its relevant diagnostic assays. This organization provides an abstracted list of infectious disorders commonly considered for the various clinical presentations and a summary of available ser...
Identification of factors associated with the development of insect bite hypersensitivity in horses in The Netherlands.
Tijdschrift voor diergeneeskunde    July 25, 2008   Volume 133, Issue 13 554-559 
van den Boom R, Ducro B, Sloet van Oldruitenborgh-Oosterbaan MM.An Internet-based questionnaire among horse owners was carried out to identify factors affecting the incidence of insect bite hypersensitivity (IBHI) among horses in the Netherlands. Information was obtained for 794 horses of various breeds, but the breed distribution was not representative for the Dutch horse population. Of the horses for which information was available, 56% suffered from IBH and 44% did not. The most common clinical symptoms were pruritus, scaling, and hair loss, occurring mainly at the base of the tail and along the mane. Breed, age, region (and local habitat), stabling, ty...
Demographics and costs of colic in Swedish horses.
Journal of veterinary internal medicine    July 24, 2008   Volume 22, Issue 4 1029-1037 doi: 10.1111/j.1939-1676.2008.0136.x
Egenvall A, Penell J, Bonnett BN, Blix J, Pringle J.Colic is an important cause of morbidity and mortality in horses. In Sweden, an insurance database with diagnostic medical information is maintained on >30% of the nation's horse population. Objective: The objective was to describe the occurrence of colic, defined by costly veterinary care and life claims, in horses at 1 insurance company during 1997-2002. HORSES: All horses (<21 years of age) with complete insurance for veterinary care and life during the period 1997-2002 were included. Methods: Colic was defined as conditions where the main clinical sign was abdominal pain and the prob...