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Topic:Epidemiology

Epidemiology in horses involves the study of the distribution and determinants of health-related states and events in equine populations. It encompasses the investigation of patterns, causes, and effects of diseases and health conditions within horse populations. This field of study aims to identify risk factors for disease and targets for preventive healthcare. Key components of equine epidemiology include disease surveillance, outbreak investigation, and the study of disease dynamics within herds or regions. Research in this area often focuses on infectious diseases, zoonotic diseases, and the impact of environmental factors on equine health. This page compiles peer-reviewed research studies and scholarly articles that explore various aspects of epidemiology in horses, including disease prevalence, transmission pathways, and strategies for disease prevention and control.
Validation of computerized Swedish horse insurance data against veterinary clinical records.
Preventive veterinary medicine    July 17, 2007   Volume 82, Issue 3-4 236-251 doi: 10.1016/j.prevetmed.2007.05.020
Penell JC, Egenvall A, Bonnett BN, Pringle J.The aim was to evaluate the agreement between computerized insurance data in a large Swedish horse insurance database and the information in the corresponding clinical records (CR). A random sample of 400 veterinary care and 140 life claims was included. Information on name of the horse, breed and gender, year of birth, specific diagnosis and system diagnosis (e.g. joints, digestive and skeletal) was compared between sources. The concordance for demographic variables was categorized as agreement, disagreement or data missing. For diagnostic information, the categories were agreement, minor dis...
Evidence-based immunization in horses.
The Veterinary clinics of North America. Equine practice    July 10, 2007   Volume 23, Issue 2 481-508 doi: 10.1016/j.cveq.2007.04.003
Barquero N, Gilkerson JR, Newton JR.Evidence of vaccine efficacy is essential for practitioners when giving advice to clients about the relative merits of different vaccines or when trying to evaluate the economic benefits of instituting a vaccine program. In equine veterinary medicine, this sort of data, which are necessary to make informed decisions about vaccine use and effectiveness, are often not available. Veterinarians need to consider the epidemiology of the disease in question, the type of vaccine that they are administering to the animal, the immunologic constraints of the vaccine technology, and the available evidence...
Community-associated MRSA SCCmec type IVd in Irish equids.
The Veterinary record    July 10, 2007   Volume 161, Issue 1 35-36 doi: 10.1136/vr.161.1.35
Maeda Y, Millar BC, Loughrey A, Goldsmith CE, Rooney PJ, Moore JE, Rao J, Buckley T, Egan C, Dooley JS, Lowery CJ, Matsuda M.No abstract available
Evidence-based gastrointestinal medicine in horses: it’s not about your gut instincts.
The Veterinary clinics of North America. Equine practice    July 10, 2007   Volume 23, Issue 2 243-266 doi: 10.1016/j.cveq.2007.03.008
Nolen-Walston R, Paxson J, Ramey DW.The use of an evidence-based approach allows veterinary clinicians to assess questions that are clinically relevant to the diagnosis and treatment of equine gastrointestinal tract disease. This approach involves formulating a clinical question, searching the literature, and answering the question with the best available evidence, with the results summarized as a clinical "bottom line." This article is organized to reinforce the principle that the cornerstone of evidence-based medicine is the clinical question. Specific questions are further categorized as to topic, with epidemiologic risk fact...
Epidemiological perspectives on Hendra virus infection in horses and flying foxes.
Australian veterinary journal    July 7, 2007   Volume 85, Issue 7 268-270 doi: 10.1111/j.1751-0813.2007.00170.x
Field HE, Breed AC, Shield J, Hedlefs RM, Pittard K, Pott B, Summers PM.No abstract available
Diversity in Indian equine rotaviruses: identification of genotype G10,P6[1] and G1 strains and a new VP7 genotype (G16) strain in specimens from diarrheic foals in India.
Journal of clinical microbiology    July 7, 2007   Volume 45, Issue 7 2354 doi: 10.1128/JCM.00900-07
Gulati BR, Deepa R, Singh BK, Rao CD.No abstract available
Comparative evaluation of Rose Bengal plate agglutination test, mallein test, and some conventional serological tests for diagnosis of equine glanders. Naureen A, Saqib M, Muhammad G, Hussain MH, Asi MN.The Rose Bengal plate agglutination test (RBT) was evaluated for the diagnosis of equine glanders, and its diagnostic efficiency was compared with that of mallein and other serological tests, including indirect hemagglutination test (IHAT), complement fixation test (CFT), and modified counter immunoelectrophoresis test (mCIET). Sera from 70 naturally infected culture-positive, 96 potentially exposed cohorts, and 110 healthy equines were tested. All tests but mCIET showed 100% specificity when testing the sera from glanders-negative equines. The calculated sensitivities of RBT, IHAT, CFT, mCIET...
Seroprevalence of Neospora spp. among asymptomatic horses, aborted mares and horses demonstrating neurological signs in Israel.
Veterinary parasitology    July 5, 2007   Volume 148, Issue 2 109-113 doi: 10.1016/j.vetpar.2007.06.002
Kligler EB, Shkap V, Baneth G, Mildenberg Z, Steinman A.Sera from 800 asymptomatic horses were examined for the presence of antibodies to Neospora caninum by immunofluorescence antibody test (IFAT). The presence of antibodies to N. caninum was also tested in sera from 52 mares that had aborted and 40 horses exhibiting neurological signs. A total of 95 (11.9%) of the 800 sera had antibodies for Neospora. Significantly higher seropositivity was obtained from horses that had neurological signs (21.2%) and from aborted mares (37.5%). There was significant linear-by-linear association between age and seropositivity. This is the first serologic survey fo...
What is your diagnosis? Onchocerciasis.
Journal of the American Veterinary Medical Association    July 4, 2007   Volume 231, Issue 1 39-40 doi: 10.2460/javma.231.1.39
Metry CA, Beard DM, Simon E.No abstract available
Risk factors for proximal sesamoid bone fractures associated with exercise history and horseshoe characteristics in Thoroughbred racehorses.
American journal of veterinary research    July 4, 2007   Volume 68, Issue 7 760-771 doi: 10.2460/ajvr.68.7.760
Anthenill LA, Stover SM, Gardner IA, Hill AE.To assess individual and combined associations of high-speed exercise and horseshoe characteristics with risk of forelimb proximal sesamoid bone fractures and proximal sesamoid bone midbody fractures in Thoroughbred racehorses. Methods: 269 deceased Thoroughbred racehorses. Methods: A case-control study design was used to compare 121 horses with a fracture of at least 1 of 4 forelimb proximal sesamoid bones (75 horses had a midbody fracture) and 148 horses without a forelimb proximal sesamoid bone fracture. Univariable and multivariable logistic regression analyses were used to evaluate potent...
Prevalence of reduced fibrinogen binding to platelets in a population of Thoroughbreds.
American journal of veterinary research    July 4, 2007   Volume 68, Issue 7 716-721 doi: 10.2460/ajvr.68.7.716
Norris JW, Pratt SM, Hunter JF, Gardner IA, Tablin F.To measure the frequency and magnitude of reduced fibrinogen binding in a population of horses from a Thoroughbred breeding farm. Methods: 444 Thoroughbred horses, 1 to 27 years old, including 316 females, 72 geldings, and 56 sexually intact males. Methods: Blood was collected from horses into tubes containingacid citrate dextrose adenine, and washed platelets were examined by use of flow cytometry for their ability to bind fibrinogen. Results: Data regarding fibrinogen binding to activated platelets were normally distributed, with nearly identical amounts of variation regardless of sex. In 3 ...
Vitamin E deficiency and risk of equine motor neuron disease.
Acta veterinaria Scandinavica    July 2, 2007   Volume 49, Issue 1 17 doi: 10.1186/1751-0147-49-17
Mohammed HO, Divers TJ, Summers BA, de Lahunta A.Equine motor neuron disease (EMND) is a spontaneous neurologic disorder of adult horses which results from the degeneration of motor neurons in the spinal cord and brain stem. Clinical manifestations, pathological findings, and epidemiologic attributes resemble those of human motor neuron disease (MND). As in MND the etiology of the disease is not known. We evaluated the predisposition role of vitamin E deficiency on the risk of EMND. Methods: Eleven horses at risk of EMND were identified and enrolled in a field trial at different times. The horses were maintained on a diet deficient in vitami...
Detection of equine herpesviruses in aborted foetuses by consensus PCR.
Veterinary microbiology    June 28, 2007   Volume 126, Issue 1-3 20-29 doi: 10.1016/j.vetmic.2007.06.019
Léon A, Fortier G, Fortier C, Freymuth F, Tapprest J, Leclercq R, Pronost S.The major role of EHV-1 in equine abortion is widely reported in the literature but the contribution of EHV-2, EHV-3, EHV-4 or EHV-5 remains less well documented. The objective of this study is to evaluate the contribution of these five different EHVs to equine abortion in a variety of biological tissues using a consensus polymerase chain reaction (PCR). The test was validated for specificity and sensitivity in horses before screening specimens from 407 foetuses, stillbirths and premature foals collected over a 2.5-year interval. Positive results obtained with this assay were compared to other...
[Detection of Babesia caballi (Nuttall, 1910) and Theileria equi (Syn. Babesia equi , Laveran, 1901) by the polymerase chain reaction (PCR) in show and sport horses in the region of Ankara].
Turkiye parazitolojii dergisi    June 28, 2007   Volume 31, Issue 2 89-93 
Güçlü HZ, Karaer KZ.The aim of this study was to compare the diagnosis of Babesia caballi and Theileria equi by the polymerase chain reaction (PCR) and microscopic examination of blood specimens collected from show and sport horses in the region of Ankara in 2004. The blood specimens were collected from randomly selected 200 show and sport horses in the region of Ankara during the tick season as well as before and after the tick season for PCR testing. At the same time, Giemsa stained peripheral blood smears were examined for the presence of Babesia spp. and also the horses were examined for the presence of ticks...
Epitope-blocking enzyme-linked immunosorbent assay to differentiate west nile virus from Japanese encephalitis virus infections in equine sera.
Clinical and vaccine immunology : CVI    June 27, 2007   Volume 14, Issue 8 1024-1031 doi: 10.1128/CVI.00051-07
Kitai Y, Shoda M, Kondo T, Konishi E.West Nile virus (WNV) is now widely distributed worldwide, except in most areas of Asia where Japanese encephalitis virus (JEV) is distributed. Considering the movement and migration of reservoir birds, there is concern that WNV may be introduced in Asian countries. Although manuals and guidelines for serological tests have been created in Japan in preparedness for the introduction of WNV, differential diagnosis between WNV and JEV may be complicated by antigenic cross-reactivities between these flaviviruses. Here, we generated a monoclonal antibody specific for the nonstructural protein 1 (NS...
[Presence of west Nile virus in northeast Mexico].
Salud publica de Mexico    June 26, 2007   Volume 49, Issue 3 210-217 doi: 10.1590/s0036-36342007000300006
Fernández-Salas I, de Lourdes Garza-Rodríguez M, Beaty BJ, Jiménez JR, Rivas-Estilla AM.To investigate the presence of WNV in birds, horses and humans in northeast Mexico. Methods: Serum samples from 33 birds, 24 horses and 237 humans were screened by ELISA for Anti-WNV antibodies. Human serum samples were also screened for WNV RNA using an RT-PCR assay. Results: Positive sera were found in three birds and 15 horses. Forty percent of the human serum samples were positive for IgG antibodies and 0% for IgM antibodies and viral RNA. Conclusions: The results of this study show that WNV is present in northeast Mexico and it is a new emergent infectious agent that represents a challeng...
Equine rhinosporidiosis.
The Veterinary record    June 26, 2007   Volume 160, Issue 25 883 doi: 10.1136/vr.160.25.883-c
Peaty M.No abstract available
Are distributions of secondary osteon variants useful for interpreting load history in mammalian bones?
Cells, tissues, organs    June 26, 2007   Volume 185, Issue 4 285-307 doi: 10.1159/000102176
Skedros JG, Sorenson SM, Jenson NH.In cortical bone, basic multicellular units (BMUs) produce secondary osteons that mediate adaptations, including variations in their population densities and cross-sectional areas. Additional important BMU-related adaptations might include atypical secondary osteon morphologies (zoned, connected, drifting, elongated, multiple canal). These variants often reflect osteonal branching that enhances toughness by increasing interfacial (cement line) complexity. If these characteristics correlate with strain mode/magnitude-related parameters of habitual loading, then BMUs might produce adaptive diffe...
Population sub-structuring among Trypanosoma evansi stocks.
Parasitology research    June 22, 2007   Volume 101, Issue 5 1215-1224 doi: 10.1007/s00436-007-0603-y
Njiru ZK, Constantine CC.To investigate the population genetic structure of Trypanosoma evansi from domesticated animals, we have analysed 112 stocks from camels, buffaloes, cattle and horses using the tandemly repeated coding sequence (MORF2) and minisatellite markers 292 and cysteine-rich acidic integral membrane protein (CRAM). We recorded a total of six alleles at the MORF2 locus, seven at 292 and 12 at the CRAM loci. Nei's genetic distance showed reduced allelic diversity between buffaloes and cattle stocks (1.2) as compared to the diversity between camels and buffaloes (3.75) and camels and cattle stock (1.69). ...
Relationships between uterine culture, cytology and pregnancy rates in a Thoroughbred practice.
Theriogenology    June 21, 2007   Volume 68, Issue 3 395-402 doi: 10.1016/j.theriogenology.2007.05.050
Riddle WT, LeBlanc MM, Stromberg AJ.Endometrial cytology and culture specimens (n=2123) were collected concurrently with a guarded uterine culture instrument from 970 mares (738 barren, 1230 foaling and 155 maiden mares) during three breeding seasons (2001-2004). Results were compared to the 28-d pregnancy rate for the cycle from which the samples were taken. Cytological smears were evaluated for inflammation at x100 and graded as: not inflammatory (0-2 neutrophils/field), moderate inflammation (2-5 neutrophils/field), severe inflammation (>5 neutrophils/field), or hypocellular (scant epithelial cells and no neutrophils). Ute...
Equine influenza in England.
The Veterinary record    June 19, 2007   Volume 160, Issue 24 851 doi: 10.1136/vr.160.24.851
Newton R, Elton D, Bryant N, Rash A, Hammond TA.No abstract available
Pathomorphological study on gastroduodenal ulceration in horses: localisation of lesions.
Acta veterinaria Hungarica    June 9, 2007   Volume 55, Issue 2 241-249 doi: 10.1556/AVet.55.2007.2.10
Bezdekova B, Jahn P, Vyskocil M.Gastroduodenal ulceration is a prevalent disease in foals and adult horses. Decreased performance as well as fatal complications relate to this syndrome. The objective of our study was to determine the prevalence of gastric ulceration in a mixed population of horses by postmortem examination and to evaluate a possible association between equine gastric ulcer syndrome (EGUS) and sex or age of the examined horses, to evaluate the localisation of lesions in the proximal part of the gastrointestinal tract and to determine the occurrence of gastric parasites. Postmortem examinations were performed ...
Possibility of selecting racehorses on jumping ability based on their steeplechase race results in France, the United Kingdom and Ireland.
Journal of animal breeding and genetics = Zeitschrift fur Tierzuchtung und Zuchtungsbiologie    June 7, 2007   Volume 124, Issue 3 124-132 doi: 10.1111/j.1439-0388.2007.00644.x
Bokor A, Blouin C, Langlois B.The aim of this study was to detect Thoroughbred mare families and sire lines, in France, in the United Kingdom and Ireland, whose offspring may be successful in steeplechase races and can be recommended therefore for sport horse breeding. Race results were collected from all steeplechase races in these countries between 1998 and 2003, which contained the results of 17,355 horses from 12,861 dams and 2452 sires. In France, non-Thoroughbred horses were also included in the analysis because they race and mate together with Thoroughbreds. Performance was measured with two criteria: earnings and r...
Is there a benefit from an early booster vaccination in the control of equine influenza?
Veterinary journal (London, England : 1997)    June 7, 2007   Volume 174, Issue 3 592-598 doi: 10.1016/j.tvjl.2007.03.004
Heldens JG, van Loon AA, van de Zande S.Conventional equine influenza vaccination schedules consist of a primary course of two vaccinations given 4-6 weeks apart followed by a third vaccination (booster) given approximately 5 months later. In between the primary course and the third vaccination, horses are generally considered not to be adequately protected against influenza. This study aimed to investigate whether Thoroughbred foals would benefit from a vaccination schedule in which the third vaccination was given earlier than in conventional vaccination schedules. The vaccines used were an inactivated whole virus equine influenza ...
Molecular characterization of the equine herpesvirus 1 strains RacL11 and Kentucky D.
The Journal of veterinary medical science    June 7, 2007   Volume 69, Issue 5 573-576 doi: 10.1292/jvms.69.573
Ghanem YM, Ibrahim el-SM, Yamada S, Matsumura T, Osterrieder N, Yamaguchi T, Fukushi H.The pathogenicities of RacL11 and Kentucky D strains of equine herpesvirus 1 in the hamster infection model are different from those of Ab4p and the Japanese isolates. Virus genome restriction fragment length polymorphism analysis and sequence comparison of an intergenic region, glycoproteins and tegument genes showed higher conservation but with some strain-specific differences. These results indicate that point nucleotide differences in RacL11 and Kentucky D might be responsible for their pathogenicity in rodent models.
Serological evidence for West Nile virus infection in horses in Croatia.
The Veterinary record    June 5, 2007   Volume 160, Issue 22 772-773 doi: 10.1136/vr.160.22.772
Madić J, Savini G, Di Gennaro A, Monaco F, Jukić B, Kovac S, Rudan N, Listes E.No abstract available
Serum antibodies in mares and foals to Actinobacillus equuli whole cells, outer membrane proteins, and Aqx toxin.
Veterinary immunology and immunopathology    June 3, 2007   Volume 118, Issue 3-4 310-316 doi: 10.1016/j.vetimm.2007.05.013
Holyoak GR, Smith CM, Boyette R, Montelongo M, Wray JH, Ayalew S, Duggan VE, Confer AW.Actinobacillus equuli is carried in the alimentary tract of mares and can cause severe septicemia of neonatal foals. A hemolytic subspecies, A. equuli subsp. haemolyticus, and a non-hemolytic subspecies, A. equuli subsp. equuli, have been identified. Hemolytic strains produce the RTX toxin Aqx. The purpose of this study was to demonstrate sequentially in two sets of mare-foal pairs antibodies to A. equuli whole bacterial cells, outer membrane proteins, and recombinant Aqx and to compare the transfer of antibodies to these antigens between mares and their foals. Two mare/foal sets of sera were ...
Statistical approaches to uncertainty: P values and confidence intervals unpacked.
Equine veterinary journal    May 25, 2007   Volume 39, Issue 3 275-276 doi: 10.1111/j.2042-3306.2007.tb00999.x
Doll H, Carney S.No abstract available
Equine herpesvirus-1-specific interferon gamma (IFNgamma) synthesis by peripheral blood mononuclear cells in thoroughbred horses.
Equine veterinary journal    May 25, 2007   Volume 39, Issue 3 202-209 doi: 10.2746/042516407x174216
Luce R, Shepherd M, Paillot R, Blacklawst B, Wood JL, Kydd JH.An assay has been developed that measures EHV-1 specific interferon gamma synthesis (IFNgamma), a cytokine produced following the activation of memory T lymphocytes and therefore a measure of cell mediated immunity. The method requires validation in the field. Objective: To measure the frequency of EHV-1 specific, IFNgamma synthesising peripheral blood mononuclear cells (PBMC) in a population of Thoroughbred horses, and examine its relationship with age, gender, premises and history of vaccination or field infection with EHV-1. Methods: Lymphocytes from 200 Thoroughbred horses were stimulated ...
Seroprevalence of antibotulinum neurotoxin type C antibodies in horses in Israel.
Equine veterinary journal    May 25, 2007   Volume 39, Issue 3 232-235 doi: 10.2746/042516407x158368
Steinman A, Kachtan I, Levi O, Shpigel NY.Clostridium botulinum type C is prevalent in Israel and outbreaks recorded in many species, other than horses. Association between levels of anti-BoNT/C antibodies and equine grass sickness (EGS) have been demonstrated but seroprevalence of anti-BoNT/C antibodies in horses has not been reported nor has EGS been reported in Israel. Objective: To determine the seroprevalence of specific anti-BoNT/C antibodies in horses in Israel and to determine whether age, breed and gender, or geographical region of farms are potential risk factors for exposure to BoNT/C. Objective: Anti-BoNT/C antibodies are ...