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Topic:Equine Health

Equine health encompasses the study and management of diseases, disorders, and overall well-being of horses. It involves understanding various physiological systems, preventive care, and treatment strategies to maintain optimal health in equine populations. Common areas of focus include nutrition, infectious diseases, orthopedic conditions, and reproductive health. Research in equine health aims to advance knowledge on diagnostic methods, therapeutic interventions, and management practices that improve horse welfare and performance. This page collects peer-reviewed research studies and scholarly articles that explore the diverse aspects of equine health, offering insights into current findings and advancements in the field.
[Precision-controlled echocardiographic left ventricular function parameters by repeated measurement on three consecutive days in trained and untrained warmblood horses].
DTW. Deutsche tierarztliche Wochenschrift    March 25, 2005   Volume 112, Issue 2 48-54 
Gehlen H, Marnette S, Rohn K, Kreienbrock L, Stadler P.Echocardiographic measurements have to be reliable and reproducible with only a low day to day variability for detecting pathological changes of left ventricular myocardial function in horses. The day dependent fluctuation margin represents an important indicator for the reproducibility of a method. To find out the day to day variability of echocardiographic parameter in healthy warmblood horses, in the present study repeated echocardiographic measurements at three consecutive days were carried out (at the same time and by the same examiner) at 11 untrained and 7 trained warmblood horses. The ...
Phenylbutazone and equine research.
The Veterinary record    March 25, 2005   Volume 156, Issue 10 327-328 doi: 10.1136/vr.156.10.327-b
Coles G.No abstract available
Polymorphisms of the upstream regulatory region of the major histocompatibility complex DRB genes in domestic horses.
International journal of immunogenetics    March 25, 2005   Volume 32, Issue 2 91-98 doi: 10.1111/j.1744-313X.2005.00496.x
Díaz S, Giovambattista G, Peral-García P.Sequence information was obtained on the variation of the ELA-DRB upstream regulatory region (URR) after polymerase chain reaction-single strand conformation polymorphism (PCR-SSCP) cloning and sequencing of approximately 220 bp upstream of the first exon of horse DRB genes. The sequence of the proximal URR of equine DRB is composed of highly conserved sequence motifs, showing the presence of the W, X, Y, CAAT and TATA conserved boxes of major histocompatibility complex (MHC) class II promoters. Five different polymorphic horse DRB promoter sequences were detected in five horse breeds. The res...
Development of cardiovascular function in the horse fetus.
The Journal of physiology    March 24, 2005   Volume 565, Issue Pt 3 1019-1030 doi: 10.1113/jphysiol.2004.078469
Giussani DA, Forhead AJ, Fowden AL.In mammals, the mechanisms regulating an increase in fetal arterial blood pressure with advancing gestational age remain unidentified. In all species studied to date, the prepartum increase in fetal plasma cortisol has an important role in the maturation of physiological systems essential for neonatal survival. In the horse, the prepartum elevation in fetal cortisol and arterial blood pressure are delayed relative to other species. Hence, the mechanisms governing the ontogenic increase in arterial blood pressure in the horse fetus may mature much closer to term than in other fetal animals. In ...
Rhodococcus equi-specific cytotoxic T lymphocytes in immune horses and development in asymptomatic foals.
Infection and immunity    March 24, 2005   Volume 73, Issue 4 2083-2093 doi: 10.1128/IAI.73.4.2083-2093.2005
Patton KM, McGuire TC, Hines MT, Mealey RH, Hines SA.Rhodococcus equi is an important cause of pneumonia in young horses; however, adult horses are immune due to their ability to mount protective recall responses. In this study, the hypothesis that R. equi-specific cytotoxic T lymphocytes (CTL) are present in the lung of immune horses was tested. Bronchoalveolar lavage (BAL)-derived pulmonary T lymphocytes stimulated with R. equi lysed infected alveolar macrophages and peripheral blood adherent cells (PBAC). As with CTL obtained from the blood, killing of R. equi-infected targets by pulmonary effectors was not restricted by equine lymphocyte all...
Modified frontonasal sinus flap surgery in standing horses: surgical findings and outcomes of 60 cases.
Equine veterinary journal    March 23, 2005   Volume 37, Issue 2 138-142 doi: 10.2746/0425164054223750
Quinn GC, Kidd JA, Lane JG.Previous studies of sinus surgery on standing horses have been based on techniques which utilise powered hand bone saws and preserve the bone flap, which was thought to be essential for a good cosmetic result. This report describes a simplified technique applied to the standing horse where the sinus flap construction used a large skull trephine and where the bone flap is necessarily discarded. Objective: To assess whether the modified standing frontonasal flap (SFF) surgery offers an effective method to investigate and/or treat sinunasal disorders in the horse. Methods: The case records of 60 ...
Diagnosing cardiac disease in equine athletes: the role of stress testing.
Equine veterinary journal    March 23, 2005   Volume 37, Issue 2 101-103 doi: 10.2746/0425164054223732
Durando M.No abstract available
Lameness associated with foot pain: results of magnetic resonance imaging in 199 horses (January 2001–December 2003) and response to treatment.
Equine veterinary journal    March 23, 2005   Volume 37, Issue 2 113-121 doi: 10.2746/0425164054223804
Dyson SJ, Murray R, Schramme MC.The diagnosis of foot-related lameness often remains elusive and it can be difficult to offer rational treatment, or to predict outcome. Objective: To describe the spectrum of injuries of the foot identified using magnetic resonance imaging (MRI), to determine their relative prevalence among MRI diagnoses and to establish the long-term results of treatment. Methods: The MR images of horses examined from January 2001--December 2003 were reviewed. Horses were selected for MRI if the pain causing lameness was localised to the foot using perineural analgesia but any clinical, radiological or ultra...
Effect of systemic lidocaine on visceral and somatic nociception in conscious horses.
Equine veterinary journal    March 23, 2005   Volume 37, Issue 2 122-127 doi: 10.2746/0425164054223723
Robertson SA, Sanchez LC, Merritt AM, Doherty TJ.Commonly used analgesics (nonsteroidal anti-inflammatory agents, opioids and alpha2-agonists) have unwanted side effects. An effective alternative with minimal adverse effects would benefit clinical equine pain management. Objective: To compare the effect of lidocaine or saline on duodenal and rectal distension threshold pressure and somatic thermal threshold in conscious mature horses. Objective: Systemically administered lidocaine would increase somatic and visceral nociceptive thresholds. Methods: Lidocaine (2 mg/kg bwt bolus followed by 50 microg/kg bwt/min for 2 h) or saline was administe...
Standing oral extraction of cheek teeth in 100 horses (1998–2003).
Equine veterinary journal    March 23, 2005   Volume 37, Issue 2 105-112 doi: 10.2746/0425164054223822
Dixon PM, Dacre I, Dacre K, Tremaine WH, McCann J, Barakzai S.Extraction of cheek teeth (CT) by the conventional repulsion technique requires general anaesthesia and carries a high rate of post operative complications. Consequently, an alternative method of extraction, i.e. orally in standing horses, was evaluated. Objective: The need for and risks of general anaesthesia could be avoided and post extraction sequelae reduced by performing extractions orally in standing horses. Methods: One hundred mainly younger horses (median age 8, range 2-18 years) with firmly attached CT that required extraction because of apical infections, displacements, diastemata,...
Effect of age at presentation on outcome following arthroscopic debridement of subchondral cystic lesions of the medial femoral condyle: 85 horses (1993–2003).
Equine veterinary journal    March 23, 2005   Volume 37, Issue 2 175-180 doi: 10.2746/0425164054223741
Smith MA, Walmsley JP, Phillips TJ, Pinchbeck GL, Booth TM, Greet TR, Richardson DW, Ross MW, Schramme MC, Singer ER, Smith RK, Clegg PD.Subchondral cystic lesions of the medial femoral condyle (SCMFC) are well documented in horses < or =3 years; arthroscopic debridement or enucleation of the cyst is currently the surgical treatment of choice. However, studies of occurence and outcome following surgery in older horses are lacking. Objective: To identify factors important in outcome for horses with SCMFC treated by arthroscopic debridement. Objective: Age of horse at presentation has a significant influence on return to work following arthroscopic treatment for SCMFC. Clinical and diagnostic findings are also significant with re...
Concentration of methylprednisolone in the centrodistal joint after administration of methylprednisolone acetate in the tarsometatarsal joint.
Equine veterinary journal    March 23, 2005   Volume 37, Issue 2 172-174 doi: 10.2746/0425164054223778
Serena A, Schumacher J, Schramme MC, Degraves F, Bell E, Ravis W.The centrodistal (CD) and tarsometatarsal (TMT) joints are often injected individually with a corticosteroid to resolve lameness caused by osteoarthritis (OA). There are no data available regarding diffusion of methylprednisolone (MP) from the TMT joint to the CD joint. Objective: A therapeutic concentration of MP diffuses into the CD joint after methylprednisolone acetate (MPA) is administered into the TMT joint. Objective: To measure the concentration of MP in the CD joint after MPA was administered into the TMT joint. Methods: MPA was administered into a TMT joint of 16 horses. At different...
Functional adaptation of articular cartilage from birth to maturity under the influence of loading: a biomechanical analysis.
Equine veterinary journal    March 23, 2005   Volume 37, Issue 2 148-154 doi: 10.2746/0425164054223769
Brommer H, Brama PA, Laasanen MS, Helminen HJ, van Weeren PR, Jurvelin JS.The concept of functional adapatation of articular cartilage during maturation has emerged from earlier biochemical research. However, articular cartilage has principally a biomechanical function governed by joint loading. Objective: To verify whether the concept of functional adaptation can be confirmed by direct measurement of biomechanical properties of cartilage. Objective: Fetuses have homogeneous (i.e. site-independent) cartilage with regard to biomechanical properties. During growth and development to maturity, the biomechanical characteristics adapt according to functional (loading) de...
Osteoarthritis of the talocalcaneal joint in 18 horses.
Equine veterinary journal    March 23, 2005   Volume 37, Issue 2 166-171 doi: 10.2746/0425164054223813
Smith RK, Dyson SJ, Schramme MC, Head MJ, Payne RJ, Platt D, Walmsley J.Talocalcaneal osteoarthritis (TO) is an uncommon cause of moderate to severe hindlimb lameness, on which only isolated case reports have been published to date. Objective: To review the clinical features of TO and determine optimal methods for diagnosis, management and prognosis. Methods: The case records from 4 referral centres of 18 horses showing hindlimb lameness considered, as a result of clinical investigation, to be caused by TO, were reviewed. Results: TO affected mature sports and pleasure horses (age 7-16 years) and caused moderate to severe lameness, usually of sudden onset with no ...
Genetic diagnosis of sex chromosome aberrations in horses based on parentage test by microsatellite DNA and analysis of X- and Y-linked markers.
Equine veterinary journal    March 23, 2005   Volume 37, Issue 2 143-147 doi: 10.2746/0425164054223787
Kakoi H, Hirota K, Gawahara H, Kurosawa M, Kuwajima M.Sex chromosome aberrations are often associated with clinical signs that affect equine health and reproduction. However, abnormal manifestation with sex chromosome aberration usually appears at maturity and potential disorders may be suspected infrequently. A reliable survey at an early stage is therefore required. Objective: To detect and characterise sex chromosome aberrations in newborn foals by the parentage test and analysis using X- and Y-linked markers. Methods: We conducted a genetic diagnosis combined with a parentage test by microsatellite DNA and analysis of X- and Y-linked genetic ...
Atropine reduces dobutamine-induced side effects in ponies undergoing a pharmacological stress protocol.
Equine veterinary journal    March 23, 2005   Volume 37, Issue 2 128-132 doi: 10.2746/0425164054223868
Sandersen CF, Detilleux J, Delguste C, Pierard L, van Loon G, Amory H.High-dose dobutamine stress echocardiography has been shown to be cardiotoxic and arrhythmogenic in horses. However, the test may have benefit in practice as a pharmacological challenge of exercise without the treadmill being required. Objective: To investigate the effect of low-dose dobutamine on cardiac performance in ponies previously treated with atropine, in order to develop a pharmacological protocol that allows examination of the equine heart under stimulation. Methods: In 13 healthy Shetland ponies, heart rate (HR), stroke index (SI) and cardiac index (CI) were calculated from pulsed-w...
In vitro comparison of three materials as apical sealants of equine premolar and molar teeth.
Equine veterinary journal    March 23, 2005   Volume 37, Issue 2 133-136 doi: 10.2746/0425164054223840
Steenkamp G, Olivier-Carstens A, van Heerden WF, Crossley DA, Boy SC.Surgical endodontic therapy is a conservative dental technique used in horses with some degree of clinical success. Failure of this procedure can partially be explained by inadequate sealing of the root apices with resultant microleakage in the periapical area. Objective: To assess and compare in vitro sealing ability of 3 different dental restorative materials used as apical sealants during equine surgical endodontics. Methods: Thirty extracted equine cheek teeth were divided randomly into 3 groups and subjected to apicoectomy and apical sealing using 3 materials: reinforced zinc oxide-eugeno...
Pain therapy in horses.
Equine veterinary journal    March 23, 2005   Volume 37, Issue 2 98-100 doi: 10.2746/0425164054223831
Muir WW.No abstract available
Clinical diagnosis and results of surgical treatment of 13 cases of acquired bilateral stringhalt (1991–2003).
Equine veterinary journal    March 23, 2005   Volume 37, Issue 2 181-183 doi: 10.2746/0425164054223877
Torre F.No abstract available
Deep digital flexor tendon force and digital mechanics in normal ponies and ponies with rotation of the distal phalanx as a sequel to laminitis.
Equine veterinary journal    March 23, 2005   Volume 37, Issue 2 161-165 doi: 10.2746/0425164054223859
McGuigan MP, Walsh TC, Pardoe CH, Day PS, Wilson AM.Previous studies have implicated tension in the deep digital flexor tendon (DDFT) in the rotation of the distal phalanx (DP) after the breakdown of the dorsal laminae caused by laminitis. Howeveer, once the DP has rotated, the DDFT should become shorter, reducing the force it exerts on the DP. Objective: To compare DDFT force and ground reaction forces (GRFs) in normal ponies and ponies with rotation of the DP as a sequel to laminitis. Methods: Six normal ponies (Group 1) and 6 sound ponies with 6-13 degrees of rotation of the DP in relation to the dorsal hoof wall (Group 2) were assessed at t...
Dose responses to inhalation of endotoxin, hay dust suspension and Aspergillus fumigatus extract in horses as measured by levels and activation of matrix metalloproteinase-9.
Equine veterinary journal    March 23, 2005   Volume 37, Issue 2 155-160 doi: 10.2746/0425164054223796
Simonen-Jokinen T, Pirie RS, McGorum B, Maisi P.Airway matrix metalloproteinases (MMPs) increase after endotoxin (LPS) exposure, but there are no reports describing dose-dependent increases or activation following exposure. Objective: To study matrix metalloproteinase-9 (MMP-9) and -2 (MMP-2) responses in bronchoalveolar lavage fluid (BALF) from heaves-susceptible and control horses following inhalation of hay dust suspension (HDS), LPS and Aspergillus fumigatus extract (AFE). Methods: Heaves-susceptible (n = 7) and control (n = 6) horses received inhalation challenges with 3 different doses of HDS and LPS. Heaves-susceptible horses (n = 6)...
Ribotyping of Burkholderia mallei isolates.
FEMS immunology and medical microbiology    March 23, 2005   Volume 44, Issue 1 91-97 doi: 10.1016/j.femsim.2004.12.002
Harvey SP, Minter JM.In this study, the subspecies differentiation of 25 isolates of Burkholderia mallei was attempted based on their ribotype polymorphisms. The isolates were from human and equine infections that occurred at various times around the world. DNA samples from each isolate were digested separately with PstI and EcoRI enzymes and probed with an Escherichia coli-derived 18-mer rDNA sequence to identify diagnostic fragments. Seventeen distinct ribotypes were identified from the combined data obtained with the two restriction enzymes. The results demonstrate the general utility of ribotyping for the subs...
Prevalence of neutralizing antibodies to Equine rhinitis A and B virus in horses and man.
Veterinary microbiology    March 22, 2005   Volume 106, Issue 3-4 293-296 doi: 10.1016/j.vetmic.2004.12.029
Kriegshäuser G, Deutz A, Kuechler E, Skern T, Lussy H, Nowotny N.Equine rhinitis viruses (ERVs) are the causative agents of mild to severe upper respiratory infections in horses worldwide. Immunologically, four serotypes of ERVs have been identified. Equine rhinitis A virus (ERAV) and Equine rhinitis B virus 1 (ERBV1) are the most frequent serotypes in Europe. Both viruses have a broad host range in cultured cells with ERAV being able to infect humans. Since there is neither information on the seroprevalence of ERAV and ERBV1 in Austria nor on the zoonotic potential of ERBV1, we investigated 200 horse and 137 veterinary sera for the presence of neutralizing...
Comparison of nonspecific indications and quantitative methods for the assessment of insulin resistance in horses and ponies.
Journal of the American Veterinary Medical Association    March 22, 2005   Volume 226, Issue 5 712-719 doi: 10.2460/javma.2005.226.712
Kronfeld DS, Treiber KH, Geor RJ.No abstract available
Prevalence and response to surgical treatment of lateral palmar intercarpal ligament avulsion in horses: 37 cases (1990-2001).
Journal of the American Veterinary Medical Association    March 22, 2005   Volume 226, Issue 5 760-766 doi: 10.2460/javma.2005.226.760
Beinlich CP, Nixon AJ.To clarify the diagnosis of avulsion of the lateral palmar intercarpal ligament (LPICL), correlate avulsion of this ligament with lameness, determine the prevalence of avulsion of the LPICL in a hospital population, and evaluate the response to surgical removal of the avulsion fragment in horses. Methods: Retrospective study. Methods: 37 horses with avulsion of the LPICL. Methods: Medical records and radiographs of horses with avulsion of the LPICL were reviewed; follow-up information was obtained from race records and from owners via a telephone survey. Results: Of 6,418 horses evaluated for ...
Use of continuous-flow peritoneal dialysis for the treatment of acute renal failure in an adult horse.
Journal of the American Veterinary Medical Association    March 22, 2005   Volume 226, Issue 5 756-732 doi: 10.2460/javma.2005.226.756
Gallatin LL, Couëtil LL, Ash SR.A 15-year-old Paso Fino gelding was evaluated because of acute renal failure following an episode of exertional rhabdomyolysis. The horse was azotemic and treated conservatively at another referral practice with no improvement in the azotemia. With conservative treatment and intermittent peritoneal dialysis, the horse had minimal improvement. Continuous-flow peritoneal dialysis (CFPD) was instituted on day 7 and continued for 3 consecutive days. Dramatic changes in the horse's attitude and serum creatinine concentration were detected within the first 24 hours of CFPD treatment. The horse remai...
[Information in communal animal housing].
Tijdschrift voor diergeneeskunde    March 19, 2005   Volume 130, Issue 5 142 
Boissevain I.No abstract available
Characterization and localization of 17 microsatellites derived from BACs in the horse.
Animal genetics    March 18, 2005   Volume 36, Issue 2 164-166 doi: 10.1111/j.1365-2052.2004.01235.x
Milenkovic D, Mariat D, Swinburne J, Chadi-Taourit S, Binns M, Guérin G.No abstract available
Effect of moxidectin selection on the genetic variation within Cylicocyclus nassatus based on amplified fragment length polymorphism (AFLP).
International journal for parasitology    March 18, 2005   Volume 35, Issue 7 813-819 doi: 10.1016/j.ijpara.2005.02.004
Tandon R, Lyons ET, Tolliver SC, Kaplan RM.Cyathostomins are among the most important intestinal nematodes of horses, yet, the literature on the molecular genetics of these worms is scarce. In this study, the technique of amplified fragment length polymorphism (AFLP) was applied to study the genetic diversity as well as to determine the effect of moxidectin selection on the population genetic diversity for Cylicocyclus nassatus, one of the most common cyathostomin species. Genomic DNAs from 30 individual male worms were used from each of two populations: an avermectin-milbemycin (AM)-naive population (Population-S) and a population der...
In vivo evaluation of an EIAV vector for the systemic genetic delivery of therapeutic antibodies.
Gene therapy    March 18, 2005   Volume 12, Issue 12 988-998 doi: 10.1038/sj.gt.3302484
Lamikanra A, Myers KA, Ferris N, Mitrophanous KA, Carroll MW.Lentiviral-based vectors hold great promise as gene delivery vehicles for the treatment of a wide variety of diseases. We have previously reported the development of a nonprimate lentiviral vector system based on the equine infectious anaemia virus (EIAV), which is able to efficiently transduce dividing and nondividing cells both in vitro and in vivo. Here, we report on the application of EIAV vectors for the systemic delivery of an antibody fusion protein designed for the treatment of cancer. The therapeutic potential of a single chain antibody against the tumour-associated antigen, 5T4, fuse...