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Topic:Equine Health

Equine health encompasses the study and management of diseases, disorders, and overall well-being of horses. It involves understanding various physiological systems, preventive care, and treatment strategies to maintain optimal health in equine populations. Common areas of focus include nutrition, infectious diseases, orthopedic conditions, and reproductive health. Research in equine health aims to advance knowledge on diagnostic methods, therapeutic interventions, and management practices that improve horse welfare and performance. This page collects peer-reviewed research studies and scholarly articles that explore the diverse aspects of equine health, offering insights into current findings and advancements in the field.
Bluetongue and equine viral arteritis viruses as models of virus-induced fetal injury and abortion.
Animal reproduction science    June 14, 2000   Volume 60-61 643-651 doi: 10.1016/s0378-4320(00)00105-6
MacLachlan NJ, Conley AJ, Kennedy PC.A number of viruses have the capacity to cross the placenta and infect the fetus to cause, among other potential outcomes, developmental defects (teratogenesis), fetal death and abortion. Bluetongue virus (BTV) infection of fetal ruminants provides an excellent model for the study of virus-induced teratogenesis. This model has shown that only viruses modified by passage in cell culture, such as modified live virus vaccine strains, readily cross the ruminant placenta, and that the timing of fetal infection determines the outcome. Thus, cerebral malformations only occur after fetal infection at ...
Post-breeding endometritis in the mare.
Animal reproduction science    June 14, 2000   Volume 60-61 221-232 doi: 10.1016/s0378-4320(00)00110-x
Watson ED.Post-breeding endometritis is a major cause of subfertility in the mare. Endometritis is a normal event in the immediate period after mating, but the presence of ultransonographically visible uterine fluid more than 12 h later is thought to be evidence of uterine pathology. In mares that are free of venerally transmitted endometritis, treatment is aimed at removing the intraluminal fluid. If the endometritis persists past day 5, when the embryo enters the uterine lumen, the cytotoxic environment will not be compatible with pregnancy. Reproductive anatomy, defective myometrial contractility, lo...
Comparative aspects of equine embryonic development.
Animal reproduction science    June 14, 2000   Volume 60-61 691-702 doi: 10.1016/s0378-4320(00)00075-0
Betteridge KJ.The developmental changes in the equine conceptus, its maternal environment and their interaction during the first 4 weeks following fertilization are reviewed. Attention is drawn to species-specific events to show why the horse is such a valuable model in which to study early pregnancy.
Use of repetitive sequence-based polymerase chain reaction for molecular epidemiologic analysis of Streptococcus equi subspecies equi.
American journal of veterinary research    June 13, 2000   Volume 61, Issue 6 699-705 doi: 10.2460/ajvr.2000.61.699
Al-Ghamdi GM, Kapur V, Ames TR, Timoney JF, Love DN, Mellencamp MA.To determine whether repetitive sequence-based polymerase chain reaction (rep-PCR) could be used to differentiate Streptococcus equi isolates, to examine S equi isolates from throughout the world, and to determine whether a horse had > 1 subtype of S equi during an outbreak of disease. Methods: An initial group of 32 S equi isolates, 63 S equi isolates from various geographic areas, and 17 S equi isolates obtained during outbreaks of disease. Methods: An aliquot of S equi genomic DNA was amplified, using enterobacterial repetitive intergenic consensus primers. Gel electrophoresis was perfor...
Imaging diagnosis–occipitoatlantoaxial malformation in a miniature horse foal. Rosenstein DS, Schott HC, Stickle RL.This research article presents a case study of a one-month-old Miniature Horse colt that was diagnosed with a rare congenital condition called occipitoatlantoaxial malformation (OAAM). Case Presentation The foal was […]
Effects of warm-up intensity on kinetics of oxygen consumption and carbon dioxide production during high-intensity exercise in horses.
American journal of veterinary research    June 13, 2000   Volume 61, Issue 6 638-645 doi: 10.2460/ajvr.2000.61.638
Geor RJ, McCutcheon LJ, Hinchcliff KW.To compare effects of low and high intensity warm-up exercise on oxygen consumption (VO2) and carbon dioxide production (VCO2) in horses. Methods: 6 moderately conditioned adult Standard-breds. Methods: Horses ran for 2 minutes at 115% of maximum oxygen consumption (VO2max), 5 minutes after each of the following periods: no warm-up (NoWU); 10 minutes at 50% of VO2max (LoWU); or 7 minutes at 50% VO2max followed by 45-second intervals at 80, 90, and 100% VO2max (HiWU). Oxygen consumption and VCO2 were measured during exercise, and kinetics of VO2 and VCO2 were calculated. Accumulated O2 deficit ...
Gait and speed as exercise components of risk factors associated with onset of fatigue injury of the third metacarpal bone in 2-year-old Thoroughbred racehorses.
American journal of veterinary research    June 13, 2000   Volume 61, Issue 6 602-608 doi: 10.2460/ajvr.2000.61.602
Boston RC, Nunamaker DM.To determine the degree to which components of the training program of 2-year-old Thoroughbred racehorses influence their susceptibility to fatigue injury of the third metacarpal bone (bucked shins). Methods: 226 two-year-old Thoroughbred racehorses. Methods: Daily training information and health reports on 2-year-old Thoroughbreds were compiled from records provided from 5 commercial stables. For each horse, data (exercise variables) were collected that comprised distance jogged (approx speed of 5 m/s), galloped (approx 11 m/s), and breezed (approx 15 to 16 m/s) until a single instance of buc...
Concentrations of substance P and prostaglandin E2 in synovial fluid of normal and abnormal joints of horses.
American journal of veterinary research    June 13, 2000   Volume 61, Issue 6 714-718 doi: 10.2460/ajvr.2000.61.714
Kirker-Head CA, Chandna VK, Agarwal RK, Morris EA, Tidwell A, O'Callaghan MW, Rand W, Kumar MS.To correlate substance P content of synovial fluid with prostaglandin E2 content, radiographic evidence of joint abnormality, and anatomic location of the joint for normal and osteoarthritic joints of horses. Methods: Synovial fluid from 46 normal joints in 21 horses and 16 osteoarthritic joints in 10 horses. Methods: Normal and osteoarthritic joints were identified by clinical and radiographic examination, by response to nerve blocks, during scintigraphy or surgery, or by clinicopathologic evaluation. Substance P and prostaglandin E2 contents of synovial fluid were determined by radioimmunoas...
Effects of interleukin-1beta and tumor necrosis factor-alpha on expression of matrix-related genes by cultured equine articular chondrocytes.
American journal of veterinary research    June 13, 2000   Volume 61, Issue 6 624-630 doi: 10.2460/ajvr.2000.61.624
Richardson DW, Dodge GR.To determine the effects of interleukin-1beta (IL-1beta) and tumor necrosis factor-alpha (TNF-alpha) on expression and regulation of several matrix-related genes by equine articular chondrocytes. Methods: Articular cartilage harvested from grossly normal joints of 8 foals, 6 yearling horses, and 8 adult horses. Methods: Chondrocytes maintained in suspension cultures were treated with various doses of human recombinant IL-1beta or TNF-alpha. Northern blots of total RNA from untreated and treated chondrocytes were probed with equine complementary DNA (cDNA) probes for cartilage matrix-related ge...
[The treatment of articular and bone infections in large animals with gentamicin-impregnated collagen sponges].
Schweizer Archiv fur Tierheilkunde    June 13, 2000   Volume 142, Issue 5 292-298 
Steiner A, Hirsbrunner G, Rytz U, Zulauf M, Philipp M, Martig J.No abstract available
Concentrations of trace minerals in the spinal cord of horses with equine motor neuron disease.
American journal of veterinary research    June 13, 2000   Volume 61, Issue 6 609-611 doi: 10.2460/ajvr.2000.61.609
Polack EW, King JM, Cummings JF, Mohammed HO, Birch M, Cronin T.To compare concentrations of trace minerals in the spinal cord of horses with equine motor neuron disease (EMND) with those of horses without neurologic disease (control horses). Methods: 24 horses with EMND and 22 control horses. Methods: Spinal cord trace mineral concentrations in horses with EMND and control horses were analyzed by use of inductively coupled plasma atomic emission spectroscopy (calcium, phosphorus, sodium, potassium, magnesium, copper, iron, manganese, nickel, zinc, aluminum, cobalt, and chromium), atomic absorption spectrophotometry (lead and cadmium), flameless atomic abs...
Pharmacokinetics of enrofloxacin administered intravenously and orally to foals.
American journal of veterinary research    June 13, 2000   Volume 61, Issue 6 706-709 doi: 10.2460/ajvr.2000.61.706
Bermingham EC, Papich MG, Vivrette SL.To determine the pharmacokinetics of enrofloxacin administered IV and orally to foals. Methods: 5 clinically normal foals. Methods: A 2-dose cross-over trial with IV and oral administration was performed. Enrofloxacin was administered once IV (5 mg/kg of body weight) to 1-week-old foals, followed by 1 oral administration (10 mg/kg) after a 7-day washout period. Blood samples were collected for 48 hours after the single dose IV and oral administrations and analyzed for plasma enrofloxacin and ciprofloxacin concentrations by use of high-performance liquid chromatography. Results: For IV administ...
[Lung function tests in horses with special reference to ultrasound-spirometry/capnography].
Schweizer Archiv fur Tierheilkunde    June 13, 2000   Volume 142, Issue 5 299-303 
Herholz C, Busato A, Straub R.No abstract available
Changes in kinematic variables observed during pressure-induced forelimb lameness in adult horses trotting on a treadmill.
American journal of veterinary research    June 13, 2000   Volume 61, Issue 6 612-619 doi: 10.2460/ajvr.2000.61.612
Keegan KG, Wilson DA, Smith BK, Wilson DJ.To determine whether kinematic changes induced by heel pressure in horses differ from those induced by toe pressure. Methods: 10 adult Quarter Horses. Methods: A shoe that applied pressure on the cuneus ungulae (frog) or on the toe was used. Kinematic analyses were performed before and after 2 levels of frog pressure and after 1 level of toe pressure. Values for stride displacement and time and joint angles were determined from horses trotting on a treadmill. Results: The first level of frog pressure caused decreases in metacarpophalangeal (fetlock) joint extension during stance and increases ...
Radiographic diagnosis–ethmoid hematoma. Gasser AM, Love NE, Tate LP.No abstract available
Pulmonary vascular pressures of thoroughbred horses exercised 1, 2, 3 and 4 h after furosemide administration.
Journal of veterinary pharmacology and therapeutics    June 10, 2000   Volume 23, Issue 2 81-89 doi: 10.1046/j.1365-2885.2000.00252.x
Magid JH, Manohar M, Goetz TE, Baker GJ, Ulbricht R, Bontkowski S, Ghantous S.Furosemide premedication of horses 4 h prior to exercise significantly attenuates exercise-induced pulmonary capillary hypertension which may help diminish the severity of exercise-induced pulmonary haemorrhage. As pulmonary hemodynamic effects of furosemide may be mediated via a reduction in plasma volume (which is most pronounced 15-30 min postfurosemide administration, with plasma volume recovering thereafter), we hypothesized that administration of furosemide at intervals shorter than 4 h before exertion may be more effective in attenuating the exercise-induced rise in pulmonary capillary ...
Pharmacokinetics of a long-acting oxytetracycline-polyethylene glycol formulation in horses.
Journal of veterinary pharmacology and therapeutics    June 10, 2000   Volume 23, Issue 2 107-110 doi: 10.1046/j.1365-2885.2000.00249.x
Dowling PM, Russell AM.No abstract available
Pharmacokinetics of fleroxacin in horses.
Journal of veterinary pharmacology and therapeutics    June 10, 2000   Volume 23, Issue 2 103-105 doi: 10.1046/j.1365-2885.2000.00248.x
Rebuelto M, Otero P, Albarellos G, Ambros L, Kreil V, Waxman S, Montoya L, Hallu R.No abstract available
Influence of interleukin-1beta and hyaluronan on proteoglycan release from equine navicular hyaline cartilage and fibrocartilage.
Journal of veterinary pharmacology and therapeutics    June 10, 2000   Volume 23, Issue 2 67-72 doi: 10.1046/j.1365-2885.2000.00247.x
Frean SP, Gettinby G, May SA, Lees P.Proteoglycan (PG) release, in response to recombinant human interleukin-1beta (rh-IL-1beta), was measured in cartilage explants obtained from the equine distal sesamoid bone (navicular bone). Fibrocartilage from the surface of the navicular bone apposing the deep digital flexor tendon and hyaline cartilage from the surface of the navicular bone articulating with the middle phalanx were labelled with 35SO4. Hyaline cartilage from the distal metacarpus was used as a control tissue. Following radiolabel incorporation, the three cartilage types were treated with rh-IL-1beta (100 U/mL) in the prese...
Streptococcus equi with truncated M-proteins isolated from outwardly healthy horses.
Microbiology (Reading, England)    June 10, 2000   Volume 146 ( Pt 6) 1361-1369 doi: 10.1099/00221287-146-6-1361
Chanter N, Talbot NC, Newton JR, Hewson D, Verheyen K.The M-protein genes of Streptococcus equi isolated from 17 outwardly healthy horses after 4 strangles outbreaks had ended, including a quarantined animal, were compared with those of S. equi isolates from 167 active cases of strangles across 4 countries. The healthy horses included 16 persistent S. equi carriers, at least one from each of the four outbreaks. These carriers, despite being outwardly healthy, had empyema of the guttural pouch(es), an enlargement of the equine Eustachian tube. A persistent carrier from two of these outbreaks, the quarantined animal and a healthy animal with normal...
[Is there a predictable correlation between time of birth, birth and the puerperal period and clinical and hormonal findings in horses?].
Berliner und Munchener tierarztliche Wochenschrift    June 10, 2000   Volume 113, Issue 5 209-214 
Glatzel PS, Kangasniemi A, Belz JP, Lange A.The investigations were done on 108 mares (78 warm-blooded horses, 25 cold-blooded horses and 5 trotters). To pursue the question in the title, progesterone and estradiol values in jugular vein-blood were examined starting from 30 days before the calculated date of parturition until 30 days after that event. In parallel to that Ca/Mg ratio was measured by means of a semiquantitative test-strip in the milk. Clinical signs of the birth, parturition itself and the post partum period were recorded. In respect to the P4 and E2 values it was that the P4:E2 ratio changed towards parturition in favour...
Risk factors for enterolithiasis among horses in Texas.
Journal of the American Veterinary Medical Association    June 9, 2000   Volume 216, Issue 11 1787-1794 doi: 10.2460/javma.2000.216.1787
Cohen ND, Vontur CA, Rakestraw PC.To identify risk factors for enterolithiasis in horses. Methods: Matched case-control study. Methods: 26 horses with enteroliths, 104 horses with other causes of colic that underwent surgery (52 horses, surgical control group) or were treated medically (52 horses, nonsurgical control group). Methods: Medical records were reviewed for horses with enteroliths and control horses. Information collected included signalment, anamnesis, and findings on physical examination and clinicopathologic testing at admission. Horses with enteroliths and control horses were compared by means of conditional logi...
Pythiosis with bone lesions in a pregnant mare.
Journal of the American Veterinary Medical Association    June 9, 2000   Volume 216, Issue 11 1795-1760 doi: 10.2460/javma.2000.216.1795
Worster AA, Lillich JD, Cox JH, Rush BR.A 9-year-old pregnant mare was referred for evaluation of a nonhealing wound of 8 weeks' duration on the lateral aspect of the left forelimb. A soft tissue mass encircled the proximal two thirds of the metacarpus; radiography revealed a moderate periosteal reaction affecting metacarpal bone i.v. Histologic and immunohistochemical examinations revealed eosinophilic granulomatous inflammation and Pythium sp in the soft tissues. The mare was treated for 12 days with antimicrobials, medicated wound dressings, debridement, and i.v. administration of sodium iodide; radiography revealed progression o...
Arthroscopic removal of patellar fracture fragments in horses: five cases (1989-1998).
Journal of the American Veterinary Medical Association    June 9, 2000   Volume 216, Issue 11 1799-1801 doi: 10.2460/javma.2000.216.1799
Marble GP, Sullins KE.To evaluate the use of arthroscopy as the primary method for removal of large patellar fracture fragments. Methods: Retrospective study. Methods: 5 performance horses of various breeds with patellar fractures. Methods: Clinical signs of lameness, external evidence of injury, and radiography were used to diagnose and determine fracture orientation. Arthroscopy of the stifle joint was performed on the affected limb with the horse positioned in dorsal recumbency and under general anesthesia. Progress after surgery was determined by evaluating medical records and via telephone conversations with o...
Incidence of equine herpesvirus 1 infection in thoroughbred weanlings on two stud farms.
Australian veterinary journal    June 7, 2000   Volume 78, Issue 4 277-278 doi: 10.1111/j.1751-0813.2000.tb11757.x
Gilkerson JR, Love DN, Whalley JM.No abstract available
A fatal case of Hendra virus infection in a horse in north Queensland: clinical and epidemiological features.
Australian veterinary journal    June 7, 2000   Volume 78, Issue 4 279-280 doi: 10.1111/j.1751-0813.2000.tb11758.x
Field HE, Barratt PC, Hughes RJ, Shield J, Sullivan ND.No abstract available
Identification and molecular characterization of Hendra virus in a horse in Queensland.
Australian veterinary journal    June 7, 2000   Volume 78, Issue 4 281-282 doi: 10.1111/j.1751-0813.2000.tb11759.x
Hooper PT, Gould AR, Hyatt AD, Braun MA, Kattenbelt JA, Hengstberger SG, Westbury HA.No abstract available
Study of the hyaloid apparatus in the neonatal thoroughbred foal.
The Veterinary record    June 6, 2000   Volume 146, Issue 20 579-584 doi: 10.1136/vr.146.20.579
Munroe G.Over 80 per cent of 169 neonatal thoroughbred foals had some part of the hyaloid artery present bilaterally and its degree of completeness, colour and character was statistically symmetrical. The complete artery was present in over 60 per cent of the foals. The incidence of the hyaloid artery and its completeness, colour and character were related to the age of the foal. The hyaloid system atrophies in the early stages of the neonatal period and generally its presence did not cause any significant ocular problems. The presence and morphology of the posterior pupillary membrane was highly corre...
Mushroom toxicity in a horse with meningioangiomatosis.
Veterinary and human toxicology    June 6, 2000   Volume 42, Issue 3 166-167 
Frazier K, Liggett A, Hines M, Styer E.We describe a fatal case of mushroom intoxication in an 18-y-o horse presumably due to Amanita verna. Horses are normally regarded as too fastidious to eat the ill-flavored toadstools. In this case, the horse had a rare benign brain tumor, meningioangiomatosis, which may have altered the horse's normal eating behavior resulting in consumption of the mushrooms.
Detecting Taxus poisoning in horses using liquid chromatography/mass spectrometry.
Veterinary and human toxicology    June 6, 2000   Volume 42, Issue 3 151-154 
Kite GC, Lawrence TJ, Dauncey EA.A method is described for the analysis of taxine alkaloids by liquid chromatography/mass spectrometry. It is applicable to the detection of taxine alkaloids in the stomach contents of horses in which Taxus poisoning is suspected. Analysis of a leaf extract of Taxus baccata revealed unreported alkaloids of the same relative molecular mass as taxine B and isotaxine B.