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Topic:Equine Health

Equine health encompasses the study and management of diseases, disorders, and overall well-being of horses. It involves understanding various physiological systems, preventive care, and treatment strategies to maintain optimal health in equine populations. Common areas of focus include nutrition, infectious diseases, orthopedic conditions, and reproductive health. Research in equine health aims to advance knowledge on diagnostic methods, therapeutic interventions, and management practices that improve horse welfare and performance. This page collects peer-reviewed research studies and scholarly articles that explore the diverse aspects of equine health, offering insights into current findings and advancements in the field.
Assessment of viability and mitochondrial function of equine spermatozoa using double staining and flow cytometry.
Theriogenology    July 15, 1997   Volume 48, Issue 2 299-312 doi: 10.1016/s0093-691x(97)84077-0
Papaioannou KZ, Murphy RP, Monks RS, Hynes N, Ryan MP, Boland MP, Roche JF.An objective double-staining method was developed to evaluate viability and mitochondrial function of stallion spermatozoa using flow cytometry. Sperm viability was assessed by propidium iodide (PI) exclusion, and mitochondrial function was measured by the intensity of rhodamine 123 (R123) fluorescence. Flow cytometry estimates of sperm viability measured by PI were equivalent (P > 0.05) to estimates made using Hoechst 33258 stain and fluorescent microscopy (% dead: 25 +/- 2.4 vs 21.5 +/- 3.5). The use of both PI and R123 was validated by addition of various proportions of freeze-shocked (m...
Evaluation of itraconazole-dimethyl sulfoxide ointment for treatment of keratomycosis in nine horses.
Journal of the American Veterinary Medical Association    July 15, 1997   Volume 211, Issue 2 199-203 
Ball MA, Rebhun WC, Gaarder JE, Patten V.To evaluate the efficacy of itraconazole-dimethyl sulfoxide ointment for treatment of keratomycosis in horses in the northeastern United States. Methods: Prospective clinical trial. Methods: 9 horses (10 affected eyes). Methods: All horses treated for keratomycosis at Cornell University between July 1994 and July 1996 were included in the study. The diagnosis of keratomycosis was confirmed by cytologic examination, and all horses were treated with 0.25 ml of a 1% itraconazole-30% dimethyl sulfoxide petrolatum-based ointment, applied to the affected eye every 4 hours. Results: Topical applicati...
Ventral peritoneal rectal tear repair in a mare.
The Veterinary record    July 12, 1997   Volume 141, Issue 2 51-52 doi: 10.1136/vr.141.2.51
David A, Butson RJ, May SA.No abstract available
Equine botulism.
The Veterinary record    July 12, 1997   Volume 141, Issue 2 56 
Dyson S, Marr CM, Barr TJ.No abstract available
Surgical treatment of a comminuted articular fracture of the accessory carpal bone in a thoroughbred horse.
The Veterinary record    July 12, 1997   Volume 141, Issue 2 47-49 doi: 10.1136/vr.141.2.47
Munroe GA, Cauvin E.The clinical, radiographic and ultrasonographic findings in a case of a comminuted articular fracture of the accessory carpal bone of a thoroughbred chaser are described, and its surgical treatment and aftercare are detailed. The horse made an uneventful recovery and successfully returned to racing.
Uterus unicornis in two mares.
The Veterinary record    July 5, 1997   Volume 141, Issue 1 21 doi: 10.1136/vr.141.1.21
Newcombe JR.No abstract available
Ageing draft and trotter horses by their dentition.
The Veterinary record    July 5, 1997   Volume 141, Issue 1 17-20 doi: 10.1136/vr.141.1.17
Muylle S, Simoens P, Lauwers H, Van Loon G.The accuracy of ageing horses by their dentition was assessed by comparing the dental features with the known dates of birth of 212 trotter horses and 189 Belgian draft horses. The horses ranged in age from two to 25 years. In both breeds it was observed that the shedding of the incisors and the appearance of the dental stars were the most reliable features for age determination. In young animals, the dental configuration was similar in both breeds. With increasing age the incisor teeth of draft horses were more liable to abrasion than those of trotter horses. The sequential changes in appeara...
The ICP0 protein of equine herpesvirus 1 is an early protein that independently transactivates expression of all classes of viral promoters.
Journal of virology    July 1, 1997   Volume 71, Issue 7 4904-4914 doi: 10.1128/JVI.71.7.4904-4914.1997
Bowles DE, Holden VR, Zhao Y, O'Callaghan DJ.To assess the role of the equine herpesvirus type 1 (EHV-1) ICP0 protein (EICP0) in gene regulation, a variety of molecular studies on the EICP0 gene and gene products of both the attenuated cell culture-adapted Kentucky A (KyA) strain and the Ab4p strain were conducted. These investigations revealed that (i) the ICP0 open reading frame (ORF) of the KyA virus strain is 1,257 bp in size and would encode a protein of 419 amino acids, and in comparison to the ICP0 gene (ORF63) of the Ab4p strain of 1,596 bp (E. A. Telford, M. S. Watson, K. McBride, and A. J. Davison, Virology 189:304-316, 1992), ...
Laparoscopic cryptorchidectomy in standing horses.
Veterinary surgery : VS    July 1, 1997   Volume 26, Issue 4 326-331 doi: 10.1111/j.1532-950x.1997.tb01505.x
Davis EW.The purpose of this study was to determine the feasibility of using laparoscopy to remove cryptorchid testes from standing horses. Methods: Prospective clinical study. Methods: Eleven client-owned horses ranging in age from 4 months to 2 years. Methods: Abdominal insufflation was initiated and maintained using a 20 F insufflation tube, attached via a stopcock, to the low pressure regulator on a standard carbon dioxide pressure tank. After trocar and laparoscope placement in the ipsilateral flank the testes were identified. Local anesthesia of the structures to be manipulated was administered t...
Strains fall mainly on the transverse plane.
The Canadian veterinary journal = La revue veterinaire canadienne    July 1, 1997   Volume 38, Issue 7 448 
Farrow CS.No abstract available
Endocrine changes in cerebrospinal fluid, pituitary effluent, and peripheral plasma of anesthetized ponies.
American journal of veterinary research    July 1, 1997   Volume 58, Issue 7 765-770 
Luna SP, Taylor PM, Bloomfield M.To investigate the effects of inhalation and total IV anesthesia on pituitary-adrenal activity in ponies. Methods: 9 healthy ponies: 5 geldings and 4 mares. Methods: Catheters were placed in the cavernous sinus below the pituitary gland and in the subarachnoid space via the lumbosacral space. After 72 hours, administration of acepromazine was followed by induction of anesthesia with thiopentone and maintenance with halothane (halothane protocol), or for the IV protocol, anesthesia induction with detomidine and ketamine was followed by maintenance with IV infusion of a detomidine-ketamine-guaif...
Utilization of both phenotypic and molecular analyses to investigate an outbreak of multidrug-resistant Salmonella anatum in horses. Hartmann FA, West SE.Phenotypic and molecular techniques, including antimicrobial susceptibility testing, plasmid analysis, and pulsed-field gel electrophoresis (PFGE) were used to characterize 15 isolates of multidrug-resistant (MDR) Salmonella anatum cultured during a 16 mo period from horses and a veterinary clinic environment. The isolates were resistant to multiple antimicrobial agents and could be placed into 4 groups based on their antimicrobial resistance patterns. The isolates contained multiple plasmids ranging in size from 2 to > 100 kb that could be grouped into 3 different plasmid profile patterns;...
Diagnosis and management of a malignant granulosa cell tumor in a holstein nulligravida: a case study.
Theriogenology    July 1, 1997   Volume 48, Issue 1 11-17 doi: 10.1016/S0093-691X(97)00188-X
Hosteller DE, Sprecher DJ, Yamini B, Ames NK.Transrectal palpation of an 18-mo-old, anestrous Holstein nulligravida revealed an enlarged left ovary. Ultrasonographically, the mass resembled known equine granulosa cell tumor (GCT) images. Slowly, virilism developed. Fifty-five days after initial diagnosis, unilateral ovariectomy was performed The presurgical serum concentration of testosterone was equal to that of a mature bull. During the 3 mo period following surgery, estrus expression resumed, the serum testosterone concentration returned to baseline, and the heifer was diagnosed pregnant following AI. A low grade, malignant GCT was th...
Clinical evaluation of the serodiagnostic value of enzyme-linked immunosorbent assay for Rhodococcus equi infection in foals.
Equine veterinary journal    July 1, 1997   Volume 29, Issue 4 274-278 doi: 10.1111/j.2042-3306.1997.tb03123.x
Higuchi T, Hashikura S, Gojo C, Inui T, Satoh S, Yoshida M, Ishiyama T, Yamada H, Takai S.An enzyme-linked immunosorbent assay (ELISA) for detection of serum IgG antibodies against Tween 20-extracted antigen of strain ATCC 6939 was applied in Hidaka, Japan to a total of 752 sick foals showing a variety of signs of infectious disease. An optical density (OD) value of more than 0.3 was tentatively fixed to be positive on the basis of readings made of healthy horse sera in previous studies. During a 2 year study, 138 of the 752 sick foals showed an OD value of 0.3 or higher and were designated as 'suspected of R. equi infection'. Age distribution during the initial medical examination...
Development and validation of a series of three-dimensional finite element models of the equine metacarpus.
Journal of biomechanics    July 1, 1997   Volume 30, Issue 7 737-742 doi: 10.1016/s0021-9290(97)00007-9
Les CM, Keyak JH, Stover SM, Taylor KT.Three-dimensional finite element (FE) models of the left metacarpi of five adult horses were developed from quantitative computed tomography data, using the algorithms of Keyak et al. (1990, J Biomed. Engng 12, 389-397). The metacarpi were then equipped with 12 rosette strain gauges and loaded non-destructively in a mechanical testing machine. The bones and the models were loaded in axial compression, with the load evenly distributed across the distal row of carpal bones, and with a point load placed mediad to the sagittal midline, to a load equivalent to three times body weight (-15 kN); and ...
Localized sequence heterogeneity in the long terminal repeats of in vivo isolates of equine infectious anemia virus.
Journal of virology    July 1, 1997   Volume 71, Issue 7 4929-4937 doi: 10.1128/JVI.71.7.4929-4937.1997
Maury W, Perryman S, Oaks JL, Seid BK, Crawford T, McGuire T, Carpenter S.The role of in vivo long terminal repeat (LTR) sequence variation of the lentivirus equine infectious anemia virus (EIAV) has not been explored. In this study, we investigated the heterogeneity found in the LTR sequences from seven EIAV-seropositive horses: three horses with clinical disease and four horses without any detectable signs of disease. LTR sequences were targeted in this study because the LTR U3 enhancer region of tissue culture-derived isolates has been identified as one of the few hypervariable regions of the EIAV genome. Furthermore, LTR variation may regulate EIAV expression in...
Equine gastric impaction, ulceration, and perforation due to persimmon (Diospyros virginiana) ingestion. Cummings CA, Copedge KJ, Confer AW.No abstract available
Borna disease virus infection in animals and humans.
Emerging infectious diseases    July 1, 1997   Volume 3, Issue 3 343-352 doi: 10.3201/eid0303.970311
Richt JA, Pfeuffer I, Christ M, Frese K, Bechter K, Herzog S.The geographic distribution and host range of Borna disease (BD), a fatal neurologic disease of horses and sheep, are larger than previously thought. The etiologic agent, Borna disease virus (BDV), has been identified as an enveloped nonsegmented negative-strand RNA virus with unique properties of replication. Data indicate a high degree of genetic stability of BDV in its natural host, the horse. Studies in the Lewis rat have shown that BDV replication does not directly influence vital functions; rather, the disease is caused by a virus-induced T-cell mediated immune reaction. Because antibodi...
Incomplete nasomaxillary dysplasia in a foal.
The Canadian veterinary journal = La revue veterinaire canadienne    July 1, 1997   Volume 38, Issue 7 445-447 
Theoret CL, Grahn BH, Fretz PB.Atresia of the nasal punctum is the most common congenital anomaly for the equine nasolacrimal system. Nasomaxillary dysplasia has not been previously documented in foals, is of unknown etiology, and appears to be a rare condition. Conjunctivomaxillary sinostomy was successful in resolving the epiphora.
Comparative studies on mammalian Müller (retinal glial) cells.
Journal of neurocytology    July 1, 1997   Volume 26, Issue 7 439-454 doi: 10.1023/a:1018525222826
Chao TI, Grosche J, Friedrich KJ, Biedermann B, Francke M, Pannicke T, Reichelt W, Wulst M, Mühle C, Pritz-Hohmeier S, Kuhrt H, Faude F, Drommer W....Müller cells from 22 mammalian species were subjected to morphological and electrophysiological studies. In the 'midperiphery' of retinae immunocytochemically labeled for vimentin, estimates of Müller cell densities per unit retinal surface area, and of neuron-to-(Müller) glia indices were performed. Müller cell densities were strikingly similar among the species studied (around 8000-11,000 mm-2) with the extremes of the horse ( or = 20,000 mm-2). By contrast, the number of neurons per Müller cell varied widely, being clustered at 6-8 (in retinae with many cones), at about 16, and at up t...
Eosinophilic enterocolitis associated with recurrent colonic impactions in a mare.
Equine veterinary journal    July 1, 1997   Volume 29, Issue 4 322-325 doi: 10.1111/j.2042-3306.1997.tb03131.x
Bassage LH, Johnston JK, Krotec KL, Meyer BS.No abstract available
Pyogranulomatous encephalitis associated with an unidentified Sarcocystis neurona-like organism in a horse. Hamir AN, Gerros TC, Dubey JP.No abstract available
Cellular heterogeneity in cathepsin D distribution in equine articular cartilage.
Equine veterinary journal    July 1, 1997   Volume 29, Issue 4 267-273 doi: 10.1111/j.2042-3306.1997.tb03122.x
Hernandez-Vidal G, Jeffcott LB, Davies ME.The distribution of cathepsin D in normal equine growth cartilage has been examined immunocytochemically using an antiserum raised against human cathepsin D. The cross-reactivity and specificity of the antiserum for equine cathepsin D was confirmed, and its lysosomal localisation was demonstrated in horse skin fibroblasts by confocal scanning microscopy. Cultured horse chondrocytes were heterogenous in their expression of cathepsin D. Heterogeneity of distribution of the enzyme was also seen in chondrocytes in cartilage from different anatomical sites. A high level of cathepsin D was observed ...
Anesthetic potency of desflurane in the horse: determination of the minimum alveolar concentration.
Veterinary surgery : VS    July 1, 1997   Volume 26, Issue 4 354-357 doi: 10.1111/j.1532-950x.1997.tb01511.x
Tendillo FJ, Mascías A, Santos M, López-Sanromán J, De Rossi R, San Román F, Gómez de Segura IA.To determine the minimum alveolar concentration (MAC) of desflurane (DES) in the horse. Methods: Prospective study. Methods: Six healthy adult horses (three males and three females) weighing 370 +/- 16 kg and aged 9 +/- 2 years old. Methods: Anesthesia was induced with DES vaporized in oxygen via a face mask connected to a large-animal, semiclosed anesthetic circle system. The horses were endotracheally intubated and positioned in right lateral recumbency. Inspired and end-tidal DES were monitored using a calibrated Ohmeda RGM 5250 multigas analyzer (Ohmeda-BOC, Spain). The MAC of desflurane t...
Transmission of some species of internal parasites in horses born in 1993, 1994, and 1995 on the same pasture on a farm in central Kentucky.
Veterinary parasitology    July 1, 1997   Volume 70, Issue 4 225-240 doi: 10.1016/s0304-4017(96)01155-7
Lyons ET, Tolliver SC, Collins SS, Drudge JH, Granstrom DE.Data are presented on the last 3 years of a 7-year study (1989-1995) on transmission of natural infections of internal parasites in horse foals (n = 27) born in 1993, 1994, and 1995 on the same pasture on a farm in central Kentucky. The foals were in a closed breeding herd of horses. Research on the first 4 years (1989-1992) of the study was published earlier (Lyons et al., 1991, 1994). Thirty-five species of endoparasites were identified, including 24 species of small strongyles. Monthly, seasonal, and host-age transmission patterns were elucidated for the parasites. Comparison of data betwee...
Cervical diskospondylitis in two horses.
Australian veterinary journal    July 1, 1997   Volume 75, Issue 7 477-479 doi: 10.1111/j.1751-0813.1997.tb14375.x
Colbourne CM, Raidal SL, Yovich JV, Howell JM, Richardson JL.No abstract available
[Case report. Cholangiopathy and cholelithiasis and acute hepatic syndrome].
Tierarztliche Praxis    July 1, 1997   Volume 25, Issue 4 317-372 
Grabner A.No abstract available
The acute phase serum amyloid A protein (SAA) in the horse: isolation and characterization of three isoforms.
Veterinary immunology and immunopathology    July 1, 1997   Volume 57, Issue 3-4 215-227 doi: 10.1016/s0165-2427(97)00021-4
Hultén C, Sletten K, Foyn Bruun C, Marhaug G.Serum amyloid A (SAA) from acute phase horse serum was isolated using hydrophobic interaction chromatography, gel filtration and ion exchange chromatography. Three SAA isoforms with different isoelectric points, i.e. SAA pI 8.0, SAA pI 9.0 and SAA pI 9.7, were identified by two-dimensional electrophoresis and further characterized with amino acid sequence analysis. These isoforms were found in similar concentrations in all animals investigated, with SAA pI 9.7 constituting about half of the total SAA content. Partial amino acid sequence analysis verified the previously published heterogeneous ...
Expression and cellular localization of inhibin alpha-subunit mRNA in equine fetal gonads.
The Journal of veterinary medical science    July 1, 1997   Volume 59, Issue 7 569-573 doi: 10.1292/jvms.59.569
Yamanouchi K, Hirasawa K, Hondo E, Hasegawa T, Ikeda A, Sugawara Y, Matsuyama S, Miyazawa K, Sawasaki T, Tojo H, Tachi C, Takahashi M.The expression of inhibin alpha-subunit mRNA in equine fetal gonads during pregnancy (Days 90 to 300) was examined by means of Northern blot analysis. In all samples examined, a single species of transcript was detected at the size of 1.5 kb. A digoxigenin-labeled antisense cRNA probe specific to equine inhibin alpha-subunit was synthesized and in situ hybridization analysis to locate the inhibin alpha-subunit mRNA positive cells was performed using frozen tissue sections of equine fetal ovary (day 150 of pregnancy) and equine fetal testis (day 180 of pregnancy). In the fetal ovary, positive c...
Disruption of sphingolipid metabolism and induction of equine leukoencephalomalacia by Fusarium proliferatum culture material containing fumonisin B(2) or B(3).
Environmental toxicology and pharmacology    July 1, 1997   Volume 3, Issue 3 221-228 doi: 10.1016/s1382-6689(97)00015-x
Riley RT, Showker JL, Owens DL, Ross PF.Fumonisin B(1), B(2), and B(3) are inhibitors of ceramide synthase, a key enzyme in the pathway for de novo sphingolipid biosynthesis. Corn, naturally contaminated with either predominantly fumonisin B(1) or pure fumonisin B(1), has been shown to cause equine leukoencephalomalacia (ELEM). It has been hypothesized that fumonisin-induced disruption of sphingolipid metabolism is an early event in the development of ELEM. Recently, it was shown that Fusarium proliferatum corn culture diets containing predominantly fumonisin B(2), but not diets which were predominantly fumonisin B(3), at 75 ppm (0....