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Topic:Equine Health

Equine health encompasses the study and management of diseases, disorders, and overall well-being of horses. It involves understanding various physiological systems, preventive care, and treatment strategies to maintain optimal health in equine populations. Common areas of focus include nutrition, infectious diseases, orthopedic conditions, and reproductive health. Research in equine health aims to advance knowledge on diagnostic methods, therapeutic interventions, and management practices that improve horse welfare and performance. This page collects peer-reviewed research studies and scholarly articles that explore the diverse aspects of equine health, offering insights into current findings and advancements in the field.
Instrumentation and techniques in respiratory surgery.
The Veterinary clinics of North America. Equine practice    August 1, 1996   Volume 12, Issue 2 351-372 doi: 10.1016/s0749-0739(17)30286-9
Stick JA.In this article, videoendoscopy in conjunction with high-speed treadmill exercise and other specialized diagnostic techniques used to measure upper airway function are reviewed as they pertain to the four most commonly diagnosed functional upper airway obstructions: (1) laryngeal hemiplegia, (2) arytenoid chondritis, (3) epiglottic entrapment, and (4) intermittent dorsal displacement of the soft palate. Using experimental and clinical findings obtained with these new instruments and diagnostic techniques, current recommendations for surgery of these obstructions are presented.
Identification of Rhodococcus equi using the polymerase chain reaction.
Letters in applied microbiology    August 1, 1996   Volume 23, Issue 2 72-74 doi: 10.1111/j.1472-765x.1996.tb00033.x
Bell KS, Philp JC, Christofi N, Aw DW.Two regions in the gene coding for 16S rRNA in Rhodococcus equi were selected as species-specific primer sequences for the polymerase chain reaction (PCR). PCR using these primers was tested against 10 strains of R. equi (including the type strain) and gave positive results for all but was negative for all other tested species of Rhodococcus; representatives of the most closely related genera and a number of other bacterial species. This method could therefore be used to identify this species which can infect the lungs or other organs of horses, pigs, humans and other animals.
A method of signal processing in motion analysis of the trotting horse.
Journal of biomechanics    August 1, 1996   Volume 29, Issue 8 1111-1114 doi: 10.1016/0021-9290(95)00179-4
Peham C, Scheidl M, Licka T.The aim of this paper is to present a method of signal processing necessary for motion analysis in the trotting horse. Motion analysis is widely used to assess lameness in horses. By definition, lameness in trot is present if the movements during the stance phases of both fore or hind limbs differ. The motion of the horse is recorded using a system for motion analysis (Selcom, 1983, SELSPOT II User Manual, Pad Nr. 6710) and the vertical motion of the head during both stance phases is compared. The symmetry is analyzed comparing the values of the Fourier coefficients. Additional head movements ...
Surgical materials and wound closure techniques.
The Veterinary clinics of North America. Equine practice    August 1, 1996   Volume 12, Issue 2 195-205 doi: 10.1016/s0749-0739(17)30279-1
Kawcak CE, Baxter GM.Recent innovations in surgical materials have helped to enhance wound healing and protect surgical wounds from infection. Materials such as polyglyconate have been evaluated in equine tissues and found efficacious. Other materials, such as poliglecaprone 25, appear to have qualities useful to equine surgery but are untested in equine tissues. Care must be taken to fully evaluate a new surgical material because its usefulness in equine tissues may not match that in human or laboratory animal tissues. Furthermore, use of disposable materials in surgery, although considered ideal for maintenance ...
Structure of equine infectious anemia virus proteinase complexed with an inhibitor.
Protein science : a publication of the Protein Society    August 1, 1996   Volume 5, Issue 8 1453-1465 doi: 10.1002/pro.5560050802
Gustchina A, Kervinen J, Powell DJ, Zdanov A, Kay J, Wlodawer A.Equine infectious anemia virus (EIAV), the causative agent of infectious anemia in horses, is a member of the lentiviral family. The virus-encoded proteinase (PR) processes viral polyproteins into functional molecules during replication and it also cleaves viral nucleocapsid protein during infection. The X-ray structure of a complex of the 154G mutant of EIAV PR with the inhibitor HBY-793 was solved at 1.8 A resolution and refined to a crystallographic R-factor of 0.136. The molecule is a dimer in which the monomers are related by a crystallographic twofold axis. Although both the enzyme and t...
Multiple gene expression in baculovirus system. Third generation vaccines for bluetongue disease and African horsesickness disease.
Annals of the New York Academy of Sciences    July 23, 1996   Volume 791 318-332 doi: 10.1111/j.1749-6632.1996.tb53539.x
Roy P.No abstract available
An attempt to reproduce ‘mal seco’ in horses by feeding them Festuca argentina.
The Veterinary record    July 20, 1996   Volume 139, Issue 3 68-70 doi: 10.1136/vr.139.3.68
Uzal FA, Woodman MP, Giraudo CG, Robles CA, Doxey DL.'Mal seco' is an almost invariably fatal disease of horses in Argentina and Chile, which resembles grass sickness, a dysautonomia of horses in Europe. The aetiology of mal seco remains unknown. An attempt to reproduce the disease was made by feeding horses with Festuca argentina, a plant considered to be toxic to animals and which was consistently found in the diet of nine horses suffering from mal seco. Three horses were fed with F argentina ad libitum for 28 days. The plant was infected with an endophytic fungus, whose morphological characteristics were in agreement with descriptions of Acre...
Flexion tests during horse-purchase examination.
The Veterinary record    July 20, 1996   Volume 139, Issue 3 76 
Plenderleith RW.No abstract available
Pergolide treatment for Cushing’s syndrome in a horse.
The Veterinary record    July 13, 1996   Volume 139, Issue 2 41-43 doi: 10.1136/vr.139.2.41
Muñoz MC, Doreste F, Ferrer O, González J, Montoya JA.A 16-year-old, male, Hanoverian horse had a three-month history of weight loss, hirsutism and polyuria/polydypsia. Examinations revealed neutrophilia, lymphopenia, hyper glycaemia and abnormalities in hepatic function. A tentative diagnosis of hyperadrenocorticism was made. The results of thyroid-releasing hormone and combined dexamethasone suppression and ACTH stimulation tests suggested the presence of a pituitary adenoma. The horse was treated with pergolide and beneficial clinical and biochemical responses were observed within one to six months.
Treatment of superficial digital flexor tendonitis.
The Veterinary record    July 13, 1996   Volume 139, Issue 2 48 
Dyson S.No abstract available
Effects of transporting horses facing either forwards or backwards on their behaviour and heart rate.
The Veterinary record    July 6, 1996   Volume 139, Issue 1 7-11 doi: 10.1136/vr.139.1.7
Waran NK, Robertson V, Cí·¯ord D, Kokoszko A, Marlin DJ.The effects of transporting horses facing either forwards or backwards were compared by transporting six thoroughbred horses in pairs in a lorry on one journey facing in the direction of travel, and on another journey facing away from the direction of travel, over a standard one-hour route. Heart rate monitors were used to record their heart rate before, during and after the journey and the horses' behaviour was recorded by scan sampling each horse every other minute. The average heart rate was significantly lower (P < 0.05) when the horses were transported facing backwards, and they also t...
Zoonoses control. Equine morbillivirus in Queensland.
Releve epidemiologique hebdomadaire    July 5, 1996   Volume 71, Issue 27 208-210 
No abstract available
Rectal biopsy diagnosis in horses with clinical signs of intestinal disorders: a retrospective study of 116 cases.
Equine veterinary journal    July 1, 1996   Volume 28, Issue 4 275-284 doi: 10.1111/j.2042-3306.1996.tb03091.x
Lindberg R, Nygren A, Persson SG.The histology from rectal biopsy specimens taken 1980-1990 on 131 occasions from 116 horses, age 1-18 years, with clinical signs of intestinal disease was evaluated and classified retrospectively. In 40 horses, autopsy results were studied for comparison. Biopsy specimens (21 horses) and post mortem rectal tissue (9 horses) from 30 healthy horses, age 4-22 years, were used as controls. In 105 clinical cases, a biopsy was performed on only one occasion, while repeat biopsy was performed in 11 cases. Specimens showed pathological changes in 60 horses. The findings were classified into acute, chr...
Generation of in vitro natural cytotoxicity of horse lymphocytes against sarcoid-derived tumor cells not expressing major histocompatibility complex antigens.
American journal of veterinary research    July 1, 1996   Volume 57, Issue 7 992-999 
Broström H, Troye-Bomberg M, Perlmann P.To analyze in vitro lymphocyte-mediated immune responses of horses with sarcoids against allogeneic sarcoid cells containing endogenous retrovirus but not expressing major histocompatibility complex antigens. Methods: Lymphocyte-mediated immune reactions were assessed by means of proliferative responses in mixed lymphocyte tumor cell culture (MLTC) assay and lymphocyte-mediated cytotoxicity against various equine target cells. Methods: 12 horses with sarcoid tumors and 15 control horses. Methods: Blood lymphocytes were cocultured in MLTC with allogeneic sarcoid cells (Mc-1, BayMc-1), equine te...
Character and duration of pharmacological effects of intravenous isoxsuprine.
Equine veterinary journal    July 1, 1996   Volume 28, Issue 4 320-326 doi: 10.1111/j.2042-3306.1996.tb03096.x
Harkins JD, Mundy GD, Stanley S, Woods WE, Sams RA, Richardson DR, Tobin T.Isoxsuprine is a therapeutic medication used to treat navicular disease and other lower limb problems in horses and is one of the more frequently detected therapeutic agents in racing horses. In a crossover study, horses were administered isoxsuprine i.v. to determine the character and duration of its pharmacological effects. Isoxsuprine significantly increased heart rate 5-150 min following injection. Unrestrained activity following isoxsuprine treatment was significantly greater than control activity for 105 min after treatment. There was an apparent, although statistically nonsignificant, i...
Cloning of a polymorphic sequence from the nontranscribed spacer of horse rDNA.
Mammalian genome : official journal of the International Mammalian Genome Society    July 1, 1996   Volume 7, Issue 7 539-541 doi: 10.1007/s003359900159
No abstract available
Reproducibility of the blood lactate-running speed curve in horses under field conditions.
American journal of veterinary research    July 1, 1996   Volume 57, Issue 7 1059-1062 
Guhl A, Lindner A, von Wittke P.To examine the reproducibility of blood lactate-running speed curve parameters derived by a curve-fit equation and by linear interpolation from the results of 4-speed tests of sport horses under field conditions. Methods: Thoroughbreds completed 10 test pairs with 3 to 11 days between tests and retest. Methods: 7 Thoroughbreds. Methods: The 4-speed test consisted of 4 runs over a distance of 2,110 m. Exercise intensity was increased by 1 m/s for each run. Blood lactate concentration measured after each run was plotted against running speed to determine the blood lactate-running speed relation....
Removal of the premaxillae and rostral portions of the maxillae of a horse.
Journal of the American Veterinary Medical Association    July 1, 1996   Volume 209, Issue 1 118-119 
Schumacher J, Kemper DL, Helman RG, Edwards JL.The incisive bones (premaxillae) and rostral portions of the maxillae of a horse were infected with dermatiaceous fungi causing phaeohyphomycosis. The pre-maxillae were exposed by creating and reflecting labial and palatal mucoperiosteal flaps, and obstetrical wire was used to remove the affected bones. Labial and palatal flaps were apposed in 2 layers, using absorbable sutures. The sutured wound healed without complication. The horse was able to prehend hay and long grass without difficulty, and the owner considered the horse's facial appearance to be nearly normal. This technique may be usef...
Necrotizing enterocolitis in horses: a retrospective study.
Journal of veterinary internal medicine    July 1, 1996   Volume 10, Issue 4 265-270 doi: 10.1111/j.1939-1676.1996.tb02060.x
Saville WJ, Hinchcliff KW, Moore BR, Kohn CW, Reed SM, Mitten LA, Rivas LJ.The clinical and clinicopathologic characteristics of fatal necrotizing enterocolitis were examined in 16 horses (age 4 months to 12 years). At initial presentation, 8 of 16 horses were pyrexic (median temperature, 38.4 degrees C; range, 33.8 to 40.6 degrees C); all 16 were tachycardic (median heart rate, 93 bpm, range, 66 to 138 bpm); 13 of 16 were tachypneic (median heart rate, 36 bpm, range, 16 to 80 bpm), dehydrated, and had discolored mucous membranes. All horses that were pyrexic were also tachycardic and tachypneic. PCV was high (> 45%) in 14 horses. Six horses were leukopenic (< 5,000 ...
The relationship between respiratory exchange ratio, plasma lactate and muscle lactate concentrations in exercising horses using a valved gas collection system. Gauvreau GM, Young SS, Staempfli H, McCutcheon LJ, Wilson BA, McDonell WN.A valved gas collection system for horses was validated, then used to examine the relationship between the respiratory exchange ratio (RER), and plasma and muscle lactate in exercising horses. Four healthy Standardbred horses were trained to breathe through the apparatus while exercising on a treadmill. Comparisons of arterial blood gas tensions were made at 3 work levels for each horse, without (control), and with the gas collection system present. At the highest work level, the arterial oxygen tension (PaO2) was significantly lower (P < 0.05), and the arterial carbon dioxide tension (PaCO2) ...
[Heart diseases in foals. A literature review exemplified by 2 case reports].
Tijdschrift voor diergeneeskunde    July 1, 1996   Volume 121, Issue 13 382-387 
de Groot J, Sloet van Oldruitenborgh-Oosterbaan MM, van der Linda-Sipman JS, Kalsbeek HC.A review of the congenital and acquired heart diseases of foals is given on the basis of two patients. A 3-month-old foal with a history of collapse after exercise had a systolic murmur on all heart valves on both sides. Necropsy revealed endocarditis ulcerosa of the left atrioventricular valves. A 6-week-old foal with systolic murmur on the left atrioventricular valves and on the aorta showed, on ultrasonography, signs of endocarditis of the atrioventricular valves. This foal recovered after a long course of antibiotics.
Effect of high-molecular weight dextran macromolecules on low-flow ischemia and reperfusion of the large colon in horses.
American journal of veterinary research    July 1, 1996   Volume 57, Issue 7 1067-1073 
Moore RM, Bertone AL, Muir WW.To evaluate the effect of high-molecular weight (MW) dextran macromolecules on low-flow ischemia and reperfusion of the large colon in horses. Methods: Horses subjected to low-flow ischemia and reperfusion of the large colon were treated with either 0.9 NaCl (group 1, n = 6) or high-MW dextran (group 2, n = 6) solutions. Methods: 12 adults horses. Methods: Horses were subjected to 3 hours' low-flow ischemia followed by 3 hours' reperfusion. A dose of either 0.9% NaCl or a 6% solution of high-MW (250,000) dextran (10 ml/kg of body weight) was administered i.v., 30 minutes prior to reperfusion. ...
Comparison and simulation of different levels of erythrocyte aggregation with pig, horse, sheep, calf, and normal human blood.
Biorheology    July 1, 1996   Volume 33, Issue 4-5 365-377 doi: 10.1016/0006-355x(96)00028-5
Weng X, Cloutier G, Pibarot P, Durand LG.Erythrocyte aggregation levels in pig, horse, sheep, and calf blood samples were investigated and compared to that of normal human blood. The aggregation kinetics and adhesive forces between red cells, and an index of structure of the aggregates were determined with an erythroaggregameter (Regulest, France) at constant hematocrit (0.40 l/l) and temperature (37 degrees C). The adhesive forces and the index of structure in pig blood were close to those of normal human blood. The results for horse blood showed a very high level of aggregation kinetics and adhesive forces between red cells. For sh...
Gait, estimated net cost of transport and heat production at different speeds in three-day-event horses.
Equine veterinary journal. Supplement    July 1, 1996   Issue 22 16-23 doi: 10.1111/j.2042-3306.1996.tb05027.x
Schroter RC, Baylis E, Marlin DJ.Heart rate and gait characteristics (stride length and frequency) were studied in 6 horses subjected to a standardised incremental exercise test, involving moving at the trot and increasing speeds up to a fast gallop and subsequently during the steeplechase phase of a 3-day-event. The studies were performed in hot conditions. Appropriate scaling, based on hindleg length (hh), stride length (L), stride frequency (f) and speed (Sp) for nondimensional stride length (lambda = (L/hh), nondimensional stride frequency (phi = f(hh/g)1/2) and nondimensional velocity (û = Sp/(ghh)1/2), where g is the g...
The diagnostic utility of cerebrospinal fluid creatine kinase activity in the horse.
Journal of veterinary internal medicine    July 1, 1996   Volume 10, Issue 4 246-251 doi: 10.1111/j.1939-1676.1996.tb02057.x
Jackson C, de Lahunta A, Divers T, Ainsworth D.We evaluated creatine kinase (CK) activity in the cerebrospinal fluid (CSF) of 128 horses with various neurological disorders. No association was found between CSF CK activity and CSF red blood cell count, CSF nucleated cell count, CSF total protein concentration, or serum CK activity. The sensitivity and specificity of CSF CK activity as a diagnostic test for protozoal myelitis in horses (61% and 56%, respectively) was higher than for cervical stenotic myelopathy, degenerative myelopathy, or motor neuron disease, but was considered to be inadequate to be of use diagnostically. Contamination o...
Sweat fluid and ion losses in horses during training and competition in cool vs. hot ambient conditions: implications for ion supplementation.
Equine veterinary journal. Supplement    July 1, 1996   Issue 22 54-62 doi: 10.1111/j.2042-3306.1996.tb05032.x
McCutcheon LJ, Geor RJ.The objectives of this study were to: 1) determine incremental and total sweat fluid and ion losses during and following (a) exercise training and (b) a treadmill Speed and Endurance exercise test (SEET) which simulated running speeds and distances required for each phase of an Olympic level (CCI****) 3-day-event in cool and hot ambient conditions and 2) determine the requirement for ion supplementation based on the calculated ion losses associated with these activities. Six exercise-trained Thoroughbred horses completed 2 weeks of exercise training in each of 2 ambient conditions: cool, dry (...
In vitro evaluation of four methods of attaching transfixation pins into a fiberglass cast for use in horses.
American journal of veterinary research    July 1, 1996   Volume 57, Issue 7 1098-1101 
McClure SR, Watkins JP, Hogan HA.To compare the axial stability provided by 4 methods of attaching transfixation pins into a fiberglass cast. Methods: Axial stability of 4 methods of transfixation pin attachment to a fiberglass cast cylinder was determined in vitro. Methods of attachment included simple incorporation of the pins into the cast, placement of a washer and nut on the pin and incorporation into the cast, extension of pins beyond the cast and attachment to a steel halo, and washers within the cast and attachment to a steel halo. Methods: A model was designed to simulate a transfixation cast applied to the equine me...
Comparison of the deduced matrix and fusion protein sequences of equine morbillivirus with cognate genes of the Paramyxoviridae.
Virus research    July 1, 1996   Volume 43, Issue 1 17-31 doi: 10.1016/0168-1702(96)01308-1
Gould AR.The nucleotide sequence of the matrix protein of equine morbillivirus (EMV) was determined to be 1062 nucleotides and coded for a deduced protein of M(r) 40148 having a net charge of + 19 at neutral pH. The matrix protein gene was separated from the P and F genes by intercistronic regions of 546 and 469 nucleotides, respectively. The nucleotide sequence which coded for the F protein was 1641 nucleotides and coded for a deduced protein of 546 amino acids having an M(r) of 60,447 and a charge + 4 at neutral pH. Partial sequence information was also determined for the P/V proteins. M, P and F pro...
Nutrition of grazing brood mares and growing horses.
Australian veterinary journal    July 1, 1996   Volume 74, Issue 1 64-70 doi: 10.1111/j.1751-0813.1996.tb13738.x
McMeniman NP.No abstract available
Evaluation of detomidine-induced analgesia in horses with chronic hoof pain.
The Journal of pharmacology and experimental therapeutics    July 1, 1996   Volume 278, Issue 1 179-184 
Owens JG, Kamerling SG, Stanton SR, Keowen ML.Detomidine (10, 20 and 40 micrograms/kg i.v.) and saline were administered to eight adult horses with hoof pain and lameness associated with chronic laminitis. Mechanical noxious stimulation was applied to 16 loci over the solar surface of each forefoot by means of an electronic hoof tester to determine chronic pain thresholds. Horses were evaluated before and at 25, 55 and 120 min after treatment for lameness and to determine hoof compression thresholds (HCTs), the percentage of responsive loci and the subjective grade of hoof withdrawal response at each responsive locus. Detomidine produced ...