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Topic:Equine Health

Equine health encompasses the study and management of diseases, disorders, and overall well-being of horses. It involves understanding various physiological systems, preventive care, and treatment strategies to maintain optimal health in equine populations. Common areas of focus include nutrition, infectious diseases, orthopedic conditions, and reproductive health. Research in equine health aims to advance knowledge on diagnostic methods, therapeutic interventions, and management practices that improve horse welfare and performance. This page collects peer-reviewed research studies and scholarly articles that explore the diverse aspects of equine health, offering insights into current findings and advancements in the field.
Fatal experimental equine arteritis virus infection of a pregnant mare: immunohistochemical staining of viral antigens. MacLachlan NJ, Balasuriya UB, Rossitto PV, Hullinger PA, Patton JF, Wilson WD.No abstract available
Laryngospasm, dysphagia, and emaciation associated with hyperkalemic periodic paralysis in a horse.
Journal of the American Veterinary Medical Association    July 1, 1996   Volume 209, Issue 1 115-117 
Guglick MA, MacAllister CG, Breazile JE.An 18-month-old Quarter Horse gelding was examined because of weight loss and dysphagia of 1 month's duration. Clinical signs included lethargy, dehydration, ptyalism, and probable aspiration pneumonia. Severe dyspnea and cyanosis were evident after mild exercise. Endoscopy revealed laryngospasm and pharyngospasm. Because clinical signs and endoscopic findings were suggestive of hyperkalemic periodic paralysis (HPP), acetazolamide treatment was instituted. Marked improvement was observed within 48 hours. The horse was determined to be homozygous for HPP. It is likely that this horse's dysphagi...
Phenylbutazone increases right atrial pressure and heart rate of running horses.
Journal of applied physiology (Bethesda, Md. : 1985)    July 1, 1996   Volume 81, Issue 1 312-317 doi: 10.1152/jappl.1996.81.1.312
Mitten LA, Hinchcliff KW, Pate JL.The effect of inhibition of cyclooxygenase activity on the hemodynamic response to exertion was examined in 6 horses. Rates of O2 consumption and CO2 production and carotid, pulmonary arterial, and right atrial pressures were measured while the horses performed a standardized exercise test on a treadmill after treatment with phenylbutazone or a placebo. Phenylbutazone (8.8 mg/kg p.o. for 2 days and 4.4 mg/kg i.v. 60 min before exertion) abolished the exertion-induced increases in plasma 6-ketoprostaglandin F1 alpha and thromboxane B2 concentrations, confirming inhibition of cyclooxygenase acti...
Equine cryptococcal endometritis and placentitis with neonatal cryptococcal pneumonia. Petrites-Murphy MB, Robbins LA, Donahue JM, Smith B.No abstract available
Induction of early-phase endotoxin tolerance in horses.
Equine veterinary journal    July 1, 1996   Volume 28, Issue 4 269-274 doi: 10.1111/j.2042-3306.1996.tb03090.x
Allen GK, Campbell-Beggs C, Robinson JA, Johnson PJ, Green EM.Six, clinically healthy horses, of mixed age and sex, were infused via a jugular venous catheter with 100 ml of pyrogenfree sterile saline (PFSS; 0.9% NaCl). Animals were infused with Escherichia coli O55:B5 endotoxin (total dose = 50 ng/kg bwt), 24 (LPS-1) and 48 h (LPS-2) after PFSS infusion. Blood was collected before, and every 15 min after, each infusion for the first 8 h and then every 2 h for the following 14 h. Clinical responses (rectal temperature, heart rate, respiration rate and blood pressure) were determined before and every 4 h after each infusion for 20 h. Geometric mean anti-e...
Leptospiral abortion in horses following a flooding incident.
Equine veterinary journal    July 1, 1996   Volume 28, Issue 4 327-330 doi: 10.1111/j.2042-3306.1996.tb03097.x
Kinde H, Hietala SK, Bolin CA, Dowe JT.No abstract available
Ultrastructure of equine morbillivirus.
Virus research    July 1, 1996   Volume 43, Issue 1 1-15 doi: 10.1016/0168-1702(96)01307-x
Hyatt AD, Selleck PW.The ultrastructure of the equine morbillivirus (EMV) which was implicated in the death of one human and fourteen horses in Queensland, Australia during September 1994 and a 36 year old man from Queensland in October 1995 is described. The ultrastructure of the virus and the intracellular virus-specific structures are characteristic for the family Paramyxoviridae. Cytoplasmic nucleocapsids were observed within the infected cells monolayers, endothelial cells (lung) of infected horses and the neurons within the brain of the 36 year old Queensland man. Aggregates of smaller nucleocapsid-like stru...
Acid-base and electrolyte effects of shortening steeplechase in a three-day-event.
Equine veterinary journal. Supplement    July 1, 1996   Issue 22 85-90 doi: 10.1111/j.2042-3306.1996.tb05035.x
Foreman JH, Grubb TL, Benson GJ, Frey LP, Foglia RA, Griffin RL.This study was designed to characterise the acid-base and electrolyte effects of shortening the distance required during steeplechase (Phase B) in the face of hot and humid weather conditions during a treadmill-simulated Speed and Endurance test. Eight conditioned Thoroughbred horses underwent 3 randomised permutations of a standardised exercise test on a high speed treadmill. Each test consisted of trotting at 3.7 m/s for 10 min (Phase A); galloping at 11 m/s (Phase B) for 4 (cool laboratory conditions), 3 (hot and humid), or 2 (hot and humid) min; trotting at 3.7 m/s for 30 min (Phase C); an...
Physiological responses in nonheat acclimated horses performing treadmill exercise in cool (20 degrees C/40% RH), hot dry (30 degrees C/40% RH) and hot humid (30 degrees C/80% RH) conditions.
Equine veterinary journal. Supplement    July 1, 1996   Issue 22 70-84 
Marlin DJ, Scott CM, Schroter RC, Mills PC, Harris RC, Harris PA, Orme CE, Roberts CA, Marr CM, Dyson SJ, Barrelet F.The aim of the present study was to determine the effect of different environmental conditions on physiological response to exercise. Four winter acclimatised, nonheat acclimated horses of different breeds were exercised at 20 degrees C/40% RH (CD), 30 degrees C/40% RH (HD) and 30 degrees C/80% RH (HH). The exercise test was designed to represent the structure and intensity of a One star Speed and Endurance test (competition exercise test [CET]). All 4 horses were able to complete the full CET (60 min + 30 min active recovery) in CD and HD, but only one horse completed the CET in HH. Two horse...
Targetting the use of beta 2-adrenoceptor agonists to meet physiological and rule book requirements.
Equine veterinary journal    July 1, 1996   Volume 28, Issue 4 250-252 doi: 10.1111/j.2042-3306.1996.tb03085.x
Nolan A, McKellar Q.No abstract available
Rectal biopsy–a piece of the diagnostic jigsaw puzzle.
Equine veterinary journal    July 1, 1996   Volume 28, Issue 4 254-255 doi: 10.1111/j.2042-3306.1996.tb03087.x
Ricketts SW.No abstract available
Control of chronic obstructive pulmonary disease in the horse.
The British veterinary journal    July 1, 1996   Volume 152, Issue 4 365-367 doi: 10.1016/s0007-1935(96)80030-3
Lekeux P, Art T, Roberts C.No abstract available
Analysis of MHC class I expression in equine trophoblast cells using in situ hybridization.
Placenta    July 1, 1996   Volume 17, Issue 5-6 351-359 doi: 10.1016/s0143-4004(96)90060-0
Maher JK, Tresnan DB, Deacon S, Hannah L, Antczak DF.Down-regulation of major histocompatibility complex (MHC) genes by trophoblast cells is considered to be a primary mechanism preventing maternal immune rejection of the fetal-placental unit in mammalian pregnancy by rendering these cells, which form the primary barrier between mother and fetus, relatively non-antigenic. In situ hybridization with probes encoding human and horse MHC class I genes was used to characterize the pattern of MHC class I mRNA expression in the various forms of horse trophoblast. Strong hybridization signals were observed in the invasive trophoblast cells of chorionic ...
Third International Workshop on Animal Locomotion: components of applied science.
Equine veterinary journal    July 1, 1996   Volume 28, Issue 4 253 doi: 10.1111/j.2042-3306.1996.tb03086.x
Deuel NR.No abstract available
Characterisation of proteins in the seminal plasma of stallions, geldings and supplemented with testosterone.
Research in veterinary science    July 1, 1996   Volume 61, Issue 1 33-37 doi: 10.1016/s0034-5288(96)90107-1
McDowell KJ, Little TV, Timoney PJ, Adams MH.The major proteins in stallion seminal plasma were characterised by two-dimensional polyacrylamide gel electrophoresis, and compared with the patterns of proteins in normal geldings (castrated males) and geldings supplemented with testosterone. The major proteins or groups of proteins identified according to their approximate relative molecular weight in kilodaltons (kDa) and apparent isoelectric point (pl) were: 1) 60 kDa. pl 7; 2) 23 kDa, pl 4-5; 3) 25-30 kDa, pl 5.5-6; 4) 23 kDa, pl 7-8; and 5) 15-20 kDa, pl 6-7.5. Protein groups 1 and 2 were more prominent in the seminal plasma from the st...
Evaluation of a biofragmentable anastomosis ring for small intestinal anastomosis in ponies.
Veterinary surgery : VS    July 1, 1996   Volume 25, Issue 4 327-335 doi: 10.1111/j.1532-950x.1996.tb01421.x
Bleyaert HF, Madison JB, Bailey JE, Johnson CM.Six ponies divided into two groups of three were used in a double crossover study design. Group 1 ponies had a small intestinal resection and anastomosis performed using a biofragmentable anastomosis ring (BAR); group 2 ponies had a hand-sewn small intestinal resection and anastomosis using a Gambee suture pattern. Approximately 30 days later, all ponies had a second celiotomy and anastomosed segments were removed. Group 1 ponies had a hand-sewn anastomosis performed and group 2 had a BAR. The anastomotic sites were collected at necropsy approximately 30 days later. Anastomosed intestinal segm...
Avulsion of the cranial cruciate ligament insertion in a horse.
Equine veterinary journal    July 1, 1996   Volume 28, Issue 4 334-336 doi: 10.1111/j.2042-3306.1996.tb03099.x
Edwards RB, Nixon AJ.No abstract available
Clinical presentation of experimentally induced rabies in horses.
Zentralblatt fur Veterinarmedizin. Reihe B. Journal of veterinary medicine. Series B    July 1, 1996   Volume 43, Issue 5 277-285 doi: 10.1111/j.1439-0450.1996.tb00315.x
Hudson LC, Weinstock D, Jordan T, Bold-Fletcher NO.Twelve naive and nine test-vaccinated horses which developed clinical signs of rabies as a result of the required protocol of a vaccine trial were prospectively observed. Nineteen of the 21 cases were confirmed positive for rabies infection of the brain by fluorescent antibody test. The two horses with negative results had ganglioneuritis of the trigeminal ganglion or lymphocytic perivascular cuffing in the brain stem in addition to clinical signs. Average incubation period was 12.3 days and average morbidity was 5.5 days. Naive animals had significantly shorter incubation and morbidity period...
Strategies for voluntary rehydration in horses during endurance exercise.
Equine veterinary journal. Supplement    July 1, 1996   Issue 22 99-106 doi: 10.1111/j.2042-3306.1996.tb05037.x
Nyman S, Jansson A, Dahlborn K, Lindholm A.To avoid dehydration and a decrease in performance capacity in horses, fluid and electrolyte losses need to be compensated for during long distance rides as well as on other occasions when sweat losses are high during exercise. Thirteen endurance-trained horses, age 5-14 years, were used to compare 3 strategies of voluntary rehydration during prolonged exercise, offering 1) water, 2) water after administering salt paste (3 x 30 g of NaCl) per os and 3) 0.9% saline. The ride covered 62 km and consisted of 3 rounds, of 20, 22 and 20 km, respectively. During the first 20 km, no fluid was offered ...
Adaptations to daily exercise in hot and humid ambient conditions in trained thoroughbred horses.
Equine veterinary journal. Supplement    July 1, 1996   Issue 22 63-68 doi: 10.1111/j.2042-3306.1996.tb05033.x
Geor RJ, McCutcheon LJ, Lindinger MI.The objectives of this study were to: 1) determine the effects of heat and high relative humidity (RH) on the clinical and physiological responses of horses during and after daily exercise training and 2) determine whether repeated exposure to, and exercise in, the heat would result in improved thermal tolerance (heat acclimation). Six trained Thoroughbred horses completed 1 h of submaximal exercise in cool, dry conditions (CD) and during a daily 4 h period of exposure to high heat and humidity (HH, room temperature = 33-35 degrees C, RH = 80-85%) for 22 days. Rectal temperature (Tre) and hear...
What is your neurologic diagnosis? Tetanus.
Journal of the American Veterinary Medical Association    July 1, 1996   Volume 209, Issue 1 57-58 
Sedrish SA, Seahorn TL, Martin G.No abstract available
Congenital polyalveolar lobe in three foals.
Journal of comparative pathology    July 1, 1996   Volume 115, Issue 1 85-88 doi: 10.1016/s0021-9975(96)80030-2
Hong CB.Three cases of congenital polyalveolar lobe (pulmonary hamartoma) were diagnosed in female Thoroughbred foals. Foal 1 was born at full term but died shortly afterwards. Foal 2 was aborted at the seventh month of gestation. Parturition was induced at the tenth month of gestation in foal 3 because it developed hydrops of the amnion and ascites. In all three foals, the polyalveolar lobe occurred on the right side and affected the entire right lung. In each case, the right lung formed a tumour-like mass, and expanded into the left chest cavity. The lung masses were pink to dark red and spongy to r...
Restoration of water and electrolyte balance in horses after repeated exercise in hot and humid conditions.
Equine veterinary journal. Supplement    July 1, 1996   Issue 22 108-112 doi: 10.1111/j.2042-3306.1996.tb05038.x
Hyyppä S, Saastamoinen M, Pösö AR.Nine adult riding horses performed on a treadmill a competition exercise test (CET) and 24 h later a standardised exercise test (SET) at mean temperature 28 degrees C and relative humidity 58%. Each horse performed the tests 5 times at 2 week intervals. The horses were given isotonic glucose-electrolyte solution via a nasogastric tube 30 min after the CET, except after the last trial when water was given. Blood lactate, plasma concentration of aldosterone, arginine vasopressin, protein, sodium, potassium, chloride, magnesium and calcium were measured. Heart rate at blood lactate concentration ...
Use of the Wet Bulb Globe Temperature (WBGT) index to quantify environmental heat loads during three-day-event competitions.
Equine veterinary journal. Supplement    July 1, 1996   Issue 22 3-6 doi: 10.1111/j.2042-3306.1996.tb05025.x
Schroter RC, Marlin DJ, Jeffcott LB.No abstract available
Acute renal disease due to Leptospira interrogans in a weanling.
Equine veterinary journal    July 1, 1996   Volume 28, Issue 4 331-333 doi: 10.1111/j.2042-3306.1996.tb03098.x
Hogan PM, Bernard WV, Kazakevicius PA, Fitzgerald MR.No abstract available
Modified ventilated capsule for the measurement of sweating rate in the exercising horse.
Equine veterinary journal. Supplement    July 1, 1996   Issue 22 48-53 doi: 10.1111/j.2042-3306.1996.tb05031.x
Scott CM, Marlin DJ, Schroter RC.Modification of a ventilated capsule technique for the measurement of sweating rate (SR) is described for application in an exercising horse. The plastic capsule was sealed against the coat of the horse. Dry air was blown through the capsule over the skin and the change in absolute humidity (g/m3) between air entering and leaving the capsule was used to calculate SR. The effect of flow rate on the response characteristics of the system was investigated and measured over a range of sweating rates in a group of horses completing a short exercise test. Repeatability of SR measurements made at 2 s...
Oral bioavailability and in vitro stability of pivampicillin, bacampicillin, talampicillin, and ampicillin in horses.
American journal of veterinary research    July 1, 1996   Volume 57, Issue 7 1021-1024 
Ensink JM, Vulto AG, van Miert AS, Tukker JJ, Winkel MB, Fluitman MA.To determine the oral bioavailabilities of 3 ampicillin esters (pivampicillin, bacampicillin, and talampicillin) and ampicillin sodium, and to determine in vitro stability of the ampicillin esters in ileal contents (pH 8.3 to 8.5). Methods: A crossover design to administer the 4 drugs orally, and ampicillin i.v. to all horses in the study. Methods: 4 healthy adult horses. Methods: The drugs were administered intragastrically to the horses at a dosage equimolar to 15 mg of ampicillin/kg of body weight. Also, ampicillin sodium was administered i.v. at the same dosage. Blood samples were taken up...
Sequence analysis and polymerase chain reaction amplification of small subunit ribosomal DNA from Sarcocystis neurona.
American journal of veterinary research    July 1, 1996   Volume 57, Issue 7 975-981 
Marsh AE, Barr BC, Madigan J, Lakritz J, Conrad PA.To identify Sarcocystis neurona-specific DNA sequences in the nuclear small subunit ribosomal RNA (nss-rRNA) gene that could be used to distinguish S neurona from other closely related protozoal parasites, and to evaluate a polymerase chain reaction (PCR) test, using broad based primers and a unique species-specific probe on CSF for detection of S neurona in equids. Methods: Sequencing of the nuclear small subunit ribosomal RNA gene from a new S neurona isolate (UCD 1) was performed. The sequence was compared with that of other closely related Sarcocystidae parasites. From this sequence, conse...
Kinematics of the distal hindlimb during stance phase in the fast trotting standardbred.
Equine veterinary journal    July 1, 1996   Volume 28, Issue 4 263-268 doi: 10.1111/j.2042-3306.1996.tb03089.x
Johnston C, Roepstorff L, Drevemo S, Kallings P.Fast trotting Standardbred horses were filmed along a straight on an oval dirt track. Five consecutive stance phases were analysed to describe the planar kinematics of the distal hindlimb. The rapid changes in the geometry of the distal hindlimb that occur during the early stance phase were studied. The hoof segment was initially braked vertically and moved in the direction of the horse. The hoof moved forward on the track surface for more than 20% of the stance time (ST). Two specific deviations in the otherwise smooth course of the fetlock joint angle appeared at 16 and 29% of ST. Tarsal ang...
Elemental composition of muscle at rest and potassium levels in muscle, plasma and sweat of horses exercising at 20 degrees C and 35 degrees C.
Equine veterinary journal. Supplement    July 1, 1996   Issue 22 35-41 doi: 10.1111/j.2042-3306.1996.tb05029.x
Gottlieb-Vedi M, Dahlborn K, Jansson A, Wroblewski R.In this study, 4 Standardbred geldings were exercised at 20 and 35 degrees C. The exercise test (ET) consisted of 2 exercise bouts separated by 2 h of rest in their boxes. Blood samples were taken before, during and after the second exercise bout and muscle (m. gluteus medius) biopsies were taken before the first exercise bout and after an intensive trot over 2600 m in the second exercise bout. The blood samples were analysed for plasma potassium and total plasma protein concentration (TPP) and the muscle fibres were analysed for elemental composition by x-ray microanalysis. The intracellular ...