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Topic:Equine Health

Equine health encompasses the study and management of diseases, disorders, and overall well-being of horses. It involves understanding various physiological systems, preventive care, and treatment strategies to maintain optimal health in equine populations. Common areas of focus include nutrition, infectious diseases, orthopedic conditions, and reproductive health. Research in equine health aims to advance knowledge on diagnostic methods, therapeutic interventions, and management practices that improve horse welfare and performance. This page collects peer-reviewed research studies and scholarly articles that explore the diverse aspects of equine health, offering insights into current findings and advancements in the field.
Application of organ culture of small intestine to the investigation of enterocyte damage by equine rotavirus.
Journal of pediatric gastroenterology and nutrition    April 1, 1995   Volume 20, Issue 3 326-332 doi: 10.1097/00005176-199504000-00011
Batt RM, Embaye H, van de Waal S, Burgess D, Edwards GB, Hart CA.We used organ culture of jejunal mucosal explants obtained from ponies aged between 2 and 12 months to study enterocyte damage by group A strains of equine rotavirus. Electron microscopy of jejunal explants maintained for < or = 48 h in the presence of organ culture medium alone showed that enterocytes were structurally intact and had a densely packed brush border and overlying mucus. Similarly, examination of explants maintained in the presence of rotavirus for 48 h revealed no apparent ultrastructural abnormalities. However, obvious replication and assembly of virus in enterocytes had occ...
[Susceptibility of bacterial isolates from the equine respiratory tract to trimethoprim, sulfadoxine, sulfadimethoxine and combinations of these compounds].
Tierarztliche Praxis    April 1, 1995   Volume 23, Issue 2 148-154 
Fey K, Schmid P.Using a broth microdilution technique, the in vitro susceptibility of bacterial isolates from the equine respiratory tract to trimethoprim, sulfadoxine, sulfadimethoxine, and combinations of these compounds was determined. The bacterial strains (n = 88) isolated recently from horses with respiratory symptoms belonged to the following species: Streptococcus equi subsp. zooepidemicus (n = 34), Streptococcus equi subsp. equi (n = 22), Staphylococcus aureus (n = 9), Klebsiella pneumoniae (n = 7), Rhodococcus equi (n = 4), Pseudomonas spp. (n = 3) and Escherichia coli (n = 3). In addition, two isol...
Treatment of olecranon bursitis in horses: 10 cases (1986-1993).
Journal of the American Veterinary Medical Association    April 1, 1995   Volume 206, Issue 7 1022-1026 
Honnas CM, Schumacher J, McClure SR, Crabill MR, Carter GK, Schmitz DG, Hoffman AG.Medical records of 10 horses with olecranon bursitis were reviewed to examine treatments, evaluate a technique for en bloc resection of the bursa in standing horses, and determine outcome of the horses after treatment. Before admission, 6 horses had been treated by needle aspiration of fluid from the mass, followed by injection of corticosteroids. Subsequent treatment for 2 of these 6 horses included open drainage and packing of the cavity with gauze soaked in 7% iodine solution. None resolved after these treatments. After admission to the hospital, 5 horses were treated medically and 5 were t...
The accuracy of predicting Thoroughbred heart scores.
New Zealand veterinary journal    April 1, 1995   Volume 43, Issue 2 57-59 doi: 10.1080/00480169.1995.35848
Blakely JA, Blakely AA.Veterinarians commonly predict mature heart scores for yearling and 2-year-old horses to aid clients in assessing a horse's racing potential. Sixty-six thoroughbreds were assessed as a yearlings or 2-year-olds, then re-assessed as a mature horse (over the age of 3). Of these horses, 82% of the yearlings and 87% of the 2-year-olds had a correctly predicted mature heart score within one heart score range (i.e. three points).
Influence of radiographically detectable orthopedic changes on racing performance in standardbred trotters.
Journal of the American Veterinary Medical Association    April 1, 1995   Volume 206, Issue 7 1013-1017 
Grøndahl AM, Engeland A.The tarsocrural, metacarpophalangeal, and metatarsophalangeal joints of 753 Standardbred yearlings were radiographed. On the basis of radiographic findings, the horses were allotted into 4 groups. Group-1 horses had osteochondrosis in the tarsocrural joints. Group-2 horses had palmar/plantar bony fragments in the metacarpo- and metatarsophalangeal joints. Group-3 horses had radiographic changes in the metacarpo- and metatarsophalangeal joint region, such as bony fragments located at the dorsoproximal end of the proximal phalanx, osteochondrosis of the sagittal ridge of the third metacarpus/met...
Cutaneous pythiosis in the horse.
The Veterinary clinics of North America. Equine practice    April 1, 1995   Volume 11, Issue 1 91-103 doi: 10.1016/s0749-0739(17)30334-6
Chaffin MK, Schumacher J, McMullan WC.Pythiosis of horses in an invasive, ulcerative, proliferative, pyogranulomatous disease of the skin and subcutis caused by Pythium insidiosum, a fungus-like oomycete in the order Peronosporales of the kingdom Protista. Pythiosis is a form of "phycomycosis," which is a complex of pyogranulomatous diseases that also includes conidiobolomysosis, basidiobolobysosis, and disorders caused by members of the order Mucorales.
Comparative treatment of mares susceptible to chronic uterine infection.
American journal of veterinary research    April 1, 1995   Volume 56, Issue 4 468-472 
Troedsson MH, Scott MA, Liu IK.Four intrauterine treatment strategies were evaluated for effectiveness in mares that were confirmed to be susceptible to chronic uterine infection. Pretreatment samples were obtained at detection of estrus, and a genital strain of Streptococcus zooepidemicus was infused into the uterus when a preovulatory (> 35 mm) follicle was detected. At 12 hours after inoculation, mares were assigned to 1 of 4 selected treatment groups: autologous plasma, 100 ml (n = 5); potassium penicillin, 5 million U in 100 ml of phosphate-buffered saline solution (PBSS; n = 5); 10 mg of prostaglandin F2 alpha in 1...
Systemic/topical therapy.
The Veterinary clinics of North America. Equine practice    April 1, 1995   Volume 11, Issue 1 127-146 doi: 10.1016/s0749-0739(17)30337-1
Rosenkrantz WS.Hopefully, the practitioner has obtained a basic broader knowledge of the options available for topical and systemic equine dermatologic therapy. There are many topical and systemic agents that can aid in the treatment of specific skin disease and there are safer alternatives to glucocorticoid therapy. Because equine dermatology is still in its infancy, there is still much to be learned. The practitioner is encouraged to pay close attention to this specialty because it will continue to evolve rapidly.
Pharmacokinetics of ketoprofen after multiple intravenous doses to mares.
Journal of veterinary pharmacology and therapeutics    April 1, 1995   Volume 18, Issue 2 108-116 doi: 10.1111/j.1365-2885.1995.tb00563.x
Sams R, Gerken DF, Ashcraft SM.The pharmacokinetics and urinary excretion of ketoprofen in six healthy mares after the first and last of five daily intravenous doses of 2.2 mg of ketoprofen per kg body weight were investigated using a high-performance liquid chromatographic (HPLC) method for determining plasma and urinary ketoprofen concentrations. Plasma ketoprofen concentrations declined triexponentially after each dose with no significant differences in plasma concentrations or pharmacokinetic parameter values between the first and last doses. The harmonic mean of the terminal elimination half-life of ketoprofen after th...
The function of the equine carpal joint: a review.
New Zealand veterinary journal    April 1, 1995   Volume 43, Issue 2 45-47 doi: 10.1080/00480169.1995.35845
Deane NJ, Davies AS.The most consistent published ideas on the function of the carpal joint of the horse concern the elasticity of the joint, and its limits to extension. Most of these are not well substantiated experimentally. Compression stress appears to be absorbed by the intercarpal ligaments as the carpal bones are separated by a wedge action during loading. Overextension is prevented by occlusion of dorsally located stop facets on the rows of carpal bones, and by the support of a stay apparatus.
Eosinophilic nodular dermatoses.
The Veterinary clinics of North America. Equine practice    April 1, 1995   Volume 11, Issue 1 75-89 doi: 10.1016/s0749-0739(17)30333-4
Mathison PT.This article describes the etiology, clinical signs, diagnosis, and treatment of various equine nodular diseases. Although of different etiologies, this group of diseases shares a common histologic reaction pattern characterized by infiltration of eosinophils and collagen degeneration. Collagenolytic granuloma, axillary nodular necrosis, unilateral papular dermatosis/eosinophilic folliculitis, amyloidosis, habronemiasis, and mast cell tumors are discussed.
Entomologic evaluation of insect hypersensitivity in horses.
The Veterinary clinics of North America. Equine practice    April 1, 1995   Volume 11, Issue 1 29-41 doi: 10.1016/s0749-0739(17)30329-2
Greiner EC.Potential methods of incriminating insects as the cause of insect hypersensitivity are presented. A listing of the biting midges known to attack horses in North America is presented also. An example of how species may be determined to be the cause of the hypersensitivity is given using data from a recent study in Florida. Light trap collections indicated the temporal and geographic distribution of potential contributing species and collections made by vacuuming horses further delineated species by proving they feed on horses and the correct locations on the horses to match lesion distribution....
Infectious crusting dermatoses.
The Veterinary clinics of North America. Equine practice    April 1, 1995   Volume 11, Issue 1 53-59 doi: 10.1016/s0749-0739(17)30331-0
Rosser EJ.Although there are numerous dermatoses in the horse in which the formation of crusts occurs, there are two relatively common and important infectious crusting dermatoses, namely, dermatophytosis and dermatophilosis. This article reviews the current concepts regarding the etiology and pathogenesis of each disease, as well as the more common clinical presentations, methods of diagnosis, and treatment.
Permeation of small molecules into the cavity of ferritin as revealed by proton nuclear magnetic resonance relaxation.
The Biochemical journal    April 1, 1995   Volume 307 ( Pt 1), Issue Pt 1 253-256 doi: 10.1042/bj3070253
Yang D, Nagayama K.The NMR relaxation technique was used to investigate the permeation of molecules into the cavity of ferritin. Spin-lattice relaxation times in the rotating frame of various probe molecules were measured for solutions of recombinant horse L-apoferritin without iron and horse spleen apoferritin with very small amounts of ferric ions. The results show that molecules larger than the size of the ferritin channels can pass through the channels into the ferritin interior, and that the maximum size of molecules for the permeation is smaller than maltotriose.
Sedative and analgesic effects of detomidine and romifidine in horses.
The Veterinary record    April 1, 1995   Volume 136, Issue 13 324-327 doi: 10.1136/vr.136.13.324
Hamm D, Turchi P, Jöchle W.In a double blind study, eight horses were treated intravenously at seven-day intervals with detomidine at doses of 10, 20 and 40 micrograms/kg, or with romifidine at doses of 40, 80 and 120 micrograms/kg, or with a placebo solution. Their sedative and analgesic effects were evaluated by objective measurements and by a clinician at 15-minute intervals for three hours and the horses' instability in stocks, locomotor ataxia and heart rate were recorded simultaneously. The administration of both drugs at all doses resulted in sedation. The sedation achieved with romifidine was significantly shall...
Problems in the diagnosis of pituitary adenoma (Cushing’s syndrome) in horses.
New Zealand veterinary journal    April 1, 1995   Volume 43, Issue 2 79-82 doi: 10.1080/00480169.1995.35854
Thompson JC, Ellison R, Gillett R, Badcoe L.Thyrotropin releasing hormone (TRH) stimulation tests were carried out on a number of horses, including one clinically affected horse whose age and clinical signs suggested that a pituitary adenoma was most unlikely. The results of these tests indicated that, according to criteria published overseas, the majority of these horses had pituitary adenomas. The fact that clinically normal or affected horses may have marked increases in cortisol concentrations indicates that the TRH stimulation test is not suitable for the diagnosis of pituitary adenoma. Other tests, including alterations in glucose...
Taxon-specific probes for the cellulolytic genus Fibrobacter reveal abundant and novel equine-associated populations.
Applied and environmental microbiology    April 1, 1995   Volume 61, Issue 4 1348-1351 doi: 10.1128/aem.61.4.1348-1351.1995
Lin C, Stahl DA.A total of six 16S rRNA targeted oligonucleotide probes were used to quantify Fibrobacter abundance and diversity in the gastrointestinal contents of a pony. Approximately 12% of the total 16S rRNA extracted from cecal contents hybridized with a Fibrobacter genus-specific probe and a Fibrobacter succinogenes species-specific probe. However, no significant hybridization was observed with a probe for the species. Fibrobacter intestinalis or with three probes for F. succinogenes subspecies. This suggested the presence of a previously undescribed population of F. succinogenes-like organisms. Novel...
Identification of Ehrlichia risticii as the causative agent of two equine abortions following natural maternal infection. Long MT, Goetz TE, Whiteley HE, Kakoma I, Lock TE.Two pregnant mares diagnosed as having equine monocytic ehrlichiosis based on history, clinical signs, and high serum antibody titers to Ehrlichia risticii aborted subsequent to recovery from illness. Mare 1 and mare 2 experienced clinical illness at 120 and 143 days of gestation and aborted at 203 and 226 days of gestation, respectively. The fetuses were expelled in fresh condition, and both mares retained their placentas upon abortion. Gross findings for the fetuses included meconium staining and petechiation of external surfaces. Internally, there was increased volume of feces within the sm...
Intravenous disposition kinetics, oral and intramuscular bioavailability and urinary excretion of norfloxacin nicotinate in donkeys.
Journal of veterinary pharmacology and therapeutics    April 1, 1995   Volume 18, Issue 2 101-107 doi: 10.1111/j.1365-2885.1995.tb00562.x
Lavy E, Ziv G, Glickman A.An aqueous solution of norfloxacin nicotinate (NFN) was administered to donkeys (Aquus asinus) intravenously (once at 10 mg/kg), intramuscularly and orally (both routes once at 10 and 20 mg/kg, and for 5 days at 20 mg/kg/day). Blood samples were collected at predetermined times after each treatment and urine was sampled after intravenous drug administration. Serum NFN concentrations were determined by microbiological assay. Intravenous injection of NFN over 45-60 s resulted in seizures, profuse sweating and tachycardia. The intravenous half-life (t1/2 beta) was 209 +/- 36 min, the apparent vol...
Maximal accumulated oxygen deficit in thoroughbred horses.
Journal of applied physiology (Bethesda, Md. : 1985)    April 1, 1995   Volume 78, Issue 4 1564-1568 doi: 10.1152/jappl.1995.78.4.1564
Eaton MD, Evans DL, Hodgson DR, Rose RJ.Thoroughbred horses have a high aerobic capacity, approximately twice that of elite human athletes. Whereas the aerobic capacity of horses can be accurately measured, there have been no measurements of anaerobic capacity. The aim of this study was to determine whether maximal accumulated O2 deficit (MAOD) could be measured in horses and used as an estimate of anaerobic capacity, as in human athletes. Six fit Thoroughbred horses were used with the exercise protocol utilizing a treadmill set at a 10% incline. O2 uptake VO2 was measured via an open-flow system for seven submaximal speeds (3-9 m/s...
Overview of equine papular and nodular dermatoses.
The Veterinary clinics of North America. Equine practice    April 1, 1995   Volume 11, Issue 1 61-74 doi: 10.1016/s0749-0739(17)30332-2
Fadok VA.Papules and nodules are common lesions on horses and have a variety of underlying causes. This article addresses inflammatory and congenital nodules primarily, including urticaria, erythema multiforme, those nodules caused by infectious agents, epidermoid and dermoid cysts, and the uniquely equine skin tumor, the sarcoid. The eosinophilic nodules and other tumors are covered elsewhere in this issue. Diagnostic and therapeutic approaches to each of the diseases are emphasized.
Comparison of aerobic capacity between racing standardbred horses.
Journal of applied physiology (Bethesda, Md. : 1985)    April 1, 1995   Volume 78, Issue 4 1447-1451 doi: 10.1152/jappl.1995.78.4.1447
Gauvreau GM, Staempfli H, McCutcheon LJ, Young SS, McDonell WN.A standardized treadmill test was used to compare metabolic and ventilatory measurements between 10 standardbred racehorses. The horses were divided into two groups: group A (n = 5) had mean racing speeds of 4.4 s faster than group B (n = 5) over a 1-mi. distance. Each horse was fitted with a venous catheter and connected to a valved gas-collection system. The exercise test consisted of 1-min incremental workloads ranging from 4.0 to 12.0 m/s at a treadmill incline of 3 degrees. Group A had significantly higher (P < 0.05) measurements of maximal O2 consumption (VO2max), O2 pulse, and tidal ...
Equine parentage testing by microsatellite locus at chromosome 1q2.1.
Animal genetics    April 1, 1995   Volume 26, Issue 2 123-124 doi: 10.1111/j.1365-2052.1995.tb02647.x
Sakagami M, Tozaki T, Mashima S, Hirota K, Mukoyama H.No abstract available
Comparative hematological study of two breeds of foals (Andalusian and Arab) subjected to exercise of progressive intensity.
The Journal of veterinary medical science    April 1, 1995   Volume 57, Issue 2 311-315 doi: 10.1292/jvms.57.311
Rubio MD, Muñoz A, Santisteban R, Tovar P, Castejón FM.Exercise-induced hematological alterations were studied in 20 four-year old foals, 11 Andalusian and 9 Arabian. They were subjected to a test exercise program consisting of 4 levels of gradually increasing intensity (15, 20, 25 and 30 km/hr) with a duration of 5 min each. Blood samples were taken during resting, after each exercise level and at 10 and 30 min of recovery from exercise. The following hematic parameters were analyzed: red blood count, hematocrit value, hemoglobin, volumetric indexes (MCV, MCH and MHCH) and total plasma proteins. The alterations as a result of the physical effort ...
Hyperplasia of the thyroid gland and musculoskeletal deformities in two equine abortuses.
The Canadian veterinary journal = La revue veterinaire canadienne    April 1, 1995   Volume 36, Issue 4 234-236 
Allen AL.No abstract available
[Clinical case. A Hannover gelding, 15 years old, jumping horse].
Tierarztliche Praxis    April 1, 1995   Volume 23, Issue 2 116-201 
Grevemeyer B, Gerhards H.No abstract available
Cloning and sequence analysis of a protective M-like protein gene from Streptococcus equi subsp. zooepidemicus.
Infection and immunity    April 1, 1995   Volume 63, Issue 4 1440-1445 doi: 10.1128/iai.63.4.1440-1445.1995
Timoney JF, Walker J, Zhou M, Ding J.Streptococcus equi subsp. zooepidemicus, a Lancefield group C streptococcus, is a frequently isolated opportunist pathogen from a variety of animal hosts, including the horse. Previous studies have indicated that equine strains carry antigens with characteristics of the antiphagocytic M proteins on the Lancefield groups A and G streptococci. We have cloned a protective M-like protein gene (SzPW60) of an equine strain of S. equi subsp. zooepidemicus W60 and determined its sequence. This gene encodes a protein with a molecular weight of 40,123 which protects mice against subsp. zooepidemicus but...
Eicosanoid concentrations in digital venous blood from horses with chronic laminitis.
American journal of veterinary research    April 1, 1995   Volume 56, Issue 4 507-510 
Owens JG, Kamerling SG, Keowen ML.The eicosanoids are a family of lipid-derived autocoids that are released in response to a variety of physical and hormonal stimuli. In this study, prostaglandin E2 (PGE2) and leukotriene B4 (LTB4) were measured in the digital veins of clinically normal horses and horses with chronic laminitis to determine whether these arachidonic acid metabolites have a role in mediating signs of hoof pain and lesions associated with chronic laminitis. Horses were evaluated at rest and after a brief exercise period, to determine whether eicosanoids are released into the circulation after mild concussion. Dig...
Parameters of forelimb ground reaction force in 48 normal ponies.
The Veterinary record    March 25, 1995   Volume 136, Issue 12 283-286 doi: 10.1136/vr.136.12.283
Barr AR, Dow SM, Goodship AE.Recordings of forelimb ground reaction forces were made from 48 normal ponies moving at the trot, to evaluate the relationships between bodyweight, vertical ground reaction forces, the timing of individual events within the stance phase and the total contact time. There were highly significant correlations between the mean vertical ground reaction forces and bodyweight. The mean vertical ground reaction forces, corrected for bodyweight, were inversely correlated with the total contact time suggesting that higher trotting speeds may be associated with greater vertical ground reaction forces. Th...
‘Normal’ blood copper levels in horses.
The Veterinary record    March 18, 1995   Volume 136, Issue 11 275 doi: 10.1136/vr.136.11.275-b
Mee JF, McLaughlin J.No abstract available