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Topic:Equine Health

Equine health encompasses the study and management of diseases, disorders, and overall well-being of horses. It involves understanding various physiological systems, preventive care, and treatment strategies to maintain optimal health in equine populations. Common areas of focus include nutrition, infectious diseases, orthopedic conditions, and reproductive health. Research in equine health aims to advance knowledge on diagnostic methods, therapeutic interventions, and management practices that improve horse welfare and performance. This page collects peer-reviewed research studies and scholarly articles that explore the diverse aspects of equine health, offering insights into current findings and advancements in the field.
Echinococcus granulosus (Taeniidae) and autochthonous echinococcosis in a North American horse.
The Journal of parasitology    February 1, 1994   Volume 80, Issue 1 141-144 
Hoberg EP, Miller S, Brown MA.We report the first documented case of autochthonous echinococcosis in a horse of North American origin. Three fully mature and viable unilocular hydatid cysts of Echinococcus granulosus (Batsch, 1786) were an incidental finding at necropsy in the liver of a 14-yr-old gelding thoroughbred that had been foaled in Virginia and raised in Maryland. Protoscolices were armed with 2 rows of 28-37 rostellar hooks; small hooks measured 23-30 microns; large hooks measured 26-33 microns. Morphologically, these were compatible with rostellar armature considered typical for the equine strain of E. granulos...
Expression cloning of an equine T-lymphocyte glycoprotein CD2 cDNA. Structure-based analysis of conserved sequence elements.
European journal of biochemistry    February 1, 1994   Volume 219, Issue 3 969-976 doi: 10.1111/j.1432-1033.1994.tb18579.x
Tavernor AS, Kydd JH, Bodian DL, Jones EY, Stuart DI, Davis SJ, Butcher GW.An equine CD2 cDNA has been isolated by monoclonal antibody screening of a T-lymphocyte cDNA library. The cDNA contained an open reading frame of 1041 bp encoding a translated product of 347 amino acids. Northern blotting analysis revealed a single mRNA species expressed in spleen, thymus and activated peripheral lymphocytes. The predicted amino acid sequence has 50-65% identity with the human, rat and mouse CD2 sequences with greatest similarity shared with the human homologue. Evolutionarily conserved structural and functional domains in CD2 were identified by comparing the sequences of the ...
Characterization, distribution, and microbiological associations of Fusobacterium spp. in clinical specimens of animal origin.
Journal of clinical microbiology    February 1, 1994   Volume 32, Issue 2 384-387 doi: 10.1128/jcm.32.2.384-387.1994
Jang SS, Hirsh DC.During the years from 1984 through 1991, 1,067 specimens from canine, equine, exotic, feline, porcine, and ruminant animal sources were found to contain members of the genus Fusobacterium: The most common sites or conditions from which members of this genus were isolated were abscesses, the respiratory tract, and pleural and peritoneal cavities. Most specimens contained a single Fusobacterium species. The most commonly isolated species was Fusobacterium necrophorum. Almost all of the specimens contained other obligate anaerobes together with facultative and obligate aerobes. The identities of ...
Adverse drug reactions: report of the Australian Veterinary Association Adverse Drug Reaction Subcommittee, 1993.
Australian veterinary journal    February 1, 1994   Volume 71, Issue 2 53-57 doi: 10.1111/j.1751-0813.1994.tb06154.x
Maddison JE.Fifty-nine reports of suspected adverse drug reactions (ADRs) were received by the Adverse Drug Reaction Subcommittee of the Australian Veterinary Association from April 1992-March 1993 inclusive. The number of reports received/number of animals involved per species was: dogs (30/43); cats (11/14); horses (8/10); cattle (9/30); ferret (1/1). Of these, 37 (63%) were classified as definite ADRs and 12 (20%) as probable ADRs. In 10 (17%) reports an ADR could not be substantiated or there was insufficient information available to make a decision. Twenty-three reports involved apparent hypersensiti...
Cardiovascular effects of intermittent positive pressure ventilation in the anesthetized horse.
The Journal of veterinary medical science    February 1, 1994   Volume 56, Issue 1 39-44 doi: 10.1292/jvms.56.39
Mizuno Y, Aida H, Hara H, Fujinaga T.Intermittent positive pressure ventilation (IPPV) is useful method for compensate of respiratory function in anesthetized horses. However, IPPV may decrease cardiac output. Alterations in cardiac output of three groups (N = 5) healthy, halothane-anesthetized mares were determined and compared during a 120 min period of anesthesia. The groups were as follows: spontaneous ventilation (SV), controlled ventilation using an end-inspiratory pressure of 20 cmH2O (CV20) and a third group using 25 cmH2O (CV25) inspiratory pressure. In the CV groups, respiratory function was adequately maintained. Altho...
Use of anabolic steroids in horses.
Journal of the American Veterinary Medical Association    February 1, 1994   Volume 204, Issue 3 329-330 
Cohen ND, Carter GK.No abstract available
Trimethoprim/sulfonamide combinations in the horse: a review.
Journal of veterinary pharmacology and therapeutics    February 1, 1994   Volume 17, Issue 1 64-73 doi: 10.1111/j.1365-2885.1994.tb00524.x
Van Duijkeren E, Vulto AG, Van Miert AS.The indications for use, side-effects, and pharmacokinetic parameters of trimethoprim, sulfonamides and their combinations in the horse are reviewed. Trimethoprim/sulfonamide (TMPS) combinations are used for the treatment of various diseases caused by gram-positive and gram-negative bacteria, including infections of the respiratory tract, urogenital tract, alimentary tract, skin joints and wounds. TMPS combinations can be administered orally, since absorption from the gastrointestinal tract is relatively good. However, peak serum concentrations can vary significantly between individual horses....
Enterolithiasis in two zebras.
Journal of the American Veterinary Medical Association    February 1, 1994   Volume 204, Issue 3 430-432 
McD○ LA, Dart AJ, Schiffman P, Parrot JJ.Enterolithiasis, as a cause of colic, was diagnosed and treated during surgical intervention in 2 Grant's zebras (Equus burchelli bohmi). The zebras were part of a wild herd in a zoo in the western United States. The clinical signs of enterolithiasis in both zebras were similar to those reported for horses. Analysis of the enterolith from 1 zebra revealed a composition identical to enteroliths that have been analyzed from horses. Three other zebras from this herd had enteroliths at necropsy. Enterolithiasis should be considered as a differential diagnosis for zebras with low-grade obstructive ...
The molecular weight of therapeutic hyaluronan (sodium hyaluronate): how significant is it?
The Journal of rheumatology    February 1, 1994   Volume 21, Issue 2 297-301 
Aviad AD, Houpt JB.Various molecular weight hyaluronic acid (HA) preparations have been injected into joints for the treatment of human and equine osteoarthritis. A therapeutic advantage has been claimed for commercial products with a molecular weight in the range found in normal synovial fluid (SF), compared to lower molecular weight products. But a correlation between molecular weight and efficacy is not borne out by an analysis of the available literature on clinical results. SF viscosity, HA concentration, HA molecular weight and rate of synthesis in joint disease. It is proposed that the beneficial effect o...
Polymorphism in the coding sequence of the horse transferrin gene.
Genome    February 1, 1994   Volume 37, Issue 1 157-165 doi: 10.1139/g94-020
Carpenter MA, Broad TE.Transferrin, the iron transport protein of the blood, is highly polymorphic in many species, including the horse. A number of sequence polymorphisms that distinguish several of the variants of horse transferrin are reported here. Previous studies indicated that exons 12 and 15 were likely to be polymorphic. Sequencing regions of exons 12 and 15 from D and R variants revealed 10 nucleotide substitutions that encoded six amino acid replacements. The F1, F2, H2, and * variants were identical to D, and the O variant was almost identical to R, in the regions studied. The data indicated that the hor...
[Basic principles and effects of hippotherapy within the comprehensive treatment of paraplegic patients].
Die Rehabilitation    February 1, 1994   Volume 33, Issue 1 39-43 
Exner G, Engelmann A, Lange K, Wenck B.A total of 67 patients, both paraplegic and quadriplegic, had participated in a hippotherapy programme over a study period of almost 18 months, with positive effects found relative to spasticity, certain pain syndromes, as well as contraction syndromes associated with impaired joint mobility. Frequently the only effective measure at all, and moreover of astonishingly lasting effect, the spasticity-reducing treatment turned out especially beneficial. Along with these statistically supported findings, a number of associated effects were noted in the physiotherapy and, especially, the nursing sec...
Comparison of oral erythromycin formulations in the horse using pharmacokinetic profiles.
Journal of veterinary pharmacology and therapeutics    February 1, 1994   Volume 17, Issue 1 17-23 doi: 10.1111/j.1365-2885.1994.tb00516.x
Ewing PJ, Burrows G, MacAllister C, Clarke C.The pharmacokinetic properties of four erythromycin formulations were compared in six adult horses after administration of single and multiple oral doses. Formulations of erythromycin administered were estolate and phosphate given 37.5 mg/kg every 12 h and 25 mg/kg every 8 h, and stearate and ethylsuccinate given 25 mg/kg every 8 h. Areas under the curve (AUC) and maximum plasma erythromycin concentrations (Cmax) were equal or greater (P > or = 0.05) following administration of erythromycin phosphate and stearate compared with those values following administration of erythromycin estolate or e...
Effect of intestinal distention on local blood flow.
American journal of veterinary research    February 1, 1994   Volume 55, Issue 2 307 
Freeman DE.No abstract available
The equine herpesvirus type 1 glycoprotein homologous to herpes simplex virus type 1 glycoprotein M is a major constituent of the virus particle.
The Journal of general virology    February 1, 1994   Volume 75 ( Pt 2) 439-442 doi: 10.1099/0022-1317-75-2-439
Pilling A, Davison AJ, Telford EA, Meredith DM.Glycoprotein 45 is a major envelope glycoprotein of equine herpesvirus type 1. The gene encoding this protein is located between map units 0.615 and 0.636 on the virus genome and evidence has suggested that it is encoded by gene 52, one of four genes within this region. Using PCR we have amplified gene 52 and subsequently cloned it into a mammalian expression vector under the control of the human cytomegalovirus immediate early gene promoter. The gene was expressed in COS-7 cells and its product was detected by immunofluorescence and Western blotting. The results indicate that glycoprotein 45 ...
Kinetic evaluation of muscle damage during exercise by calculation of amount of creatine kinase released.
The American journal of physiology    February 1, 1994   Volume 266, Issue 2 Pt 2 R434-R441 doi: 10.1152/ajpregu.1994.266.2.R434
Volfinger L, Lassourd V, Michaux JM, Braun JP, Toutain PL.To quantify the extent of muscle alteration during prolonged exercise, the release rate of creatine kinase (CK) from striated muscle was measured in six horses during a rest period (6 h) and during three exercise tests (15, 30, and 60 km) at a constant speed of 200 m/min. CK clearance was measured after intravenous bolus administration (150 U/kg) of a CK solution obtained from horse muscle. The CK steady-state volume of distribution was 0.059 +/- 0.0215 l/kg, the terminal half-life was 123 +/- 28 min, and the plasma clearance was 0.36 +/- 0.10 ml.kg-1 x min-1. After an intramuscular CK adminis...
Ovarian follicular growth and development in mammals.
Biology of reproduction    February 1, 1994   Volume 50, Issue 2 225-232 doi: 10.1095/biolreprod50.2.225
Fortune JE.Evidence from several species indicates that the initial stages of follicular growth proceed very slowly. In contrast, the stages after antrum formation are much more rapid. Atresia seems to be most prevalent as follicles approach the size at which they could be recruited for potential ovulation. Although most follicles become atretic around that stage, a few are recruited into a cohort or wave of follicles that continue to grow beyond the stage at which atresia normally occurs. Next, a species-specific number of follicles is selected for dominance. In some species (e.g. rats, primates, pigs),...
Preparation and characterization of monoclonal antibodies against equine chondrocytes, osteoblasts and osteocytes.
Zentralblatt fur Veterinarmedizin. Reihe A    February 1, 1994   Volume 41, Issue 1 31-36 doi: 10.1111/j.1439-0442.1994.tb00062.x
Katayama Y, Oikawa M, Kaneko M, Yoshihara T, Yoshikawa H, Yoshikawa T.Three monoclonal antibodies capable of individually recognizing chondrocytes, osteoblasts and osteocytes were prepared. EB-1 reacted with a 55-kDa antigen on the chondrocyte membrane, EB-2 with a 110-kDa antigen on the membrane of osteoblasts and/or partial osteocytes, and EB-3 with a 130-kDa antigen on the membrane of osteocytes. These monoclonal antibodies may be useful probes for studying the differentiation and maturation of osteogenic cells.
Detection of Borna disease virus RNA in naturally infected animals by a nested polymerase chain reaction.
Journal of virological methods    February 1, 1994   Volume 46, Issue 2 133-143 doi: 10.1016/0166-0934(94)90098-1
Zimmermann W, Dürrwald R, Ludwig H.Borna disease virus in naturally infected horses, a donkey and sheep was detected for the first time by amplification of viral RNA using PCR. In contrast to a control group of healthy horses, brain tissue was positive by this assay in all animals with neurological symptoms. The use of a second round of PCR with nested primers following Southern hybridization confirmed the specificity and increased the sensitivity of the test. Comparison with conventional methods recommends this technique for monitoring of BDV infections at a molecular level.
Structure determination of the disialylated poly-(N-acetyllactosamine)-containing O-linked carbohydrate chains of equine chorionic gonadotropin.
Glycoconjugate journal    February 1, 1994   Volume 11, Issue 1 35-41 doi: 10.1007/BF00732430
Hokke CH, Roosenboom MJ, Thomas-Oates JE, Kamerling JP, Vliegenthart JF.The disialylated poly-(N-acetyllactosamine)-containing O-linked oligosaccharide alditols, released by alkaline borohydride treatment of the enzymically N-deglycosylated beta-subunit of equine chorionic gonadotropin, were purified by fast protein liquid chromatography (FPLC) on Mono Q and analysed by fast ion bombardment mass spectrometry (FAB-MS) and 1H-NMR spectroscopy. The identified oligosaccharide alditols have the following structure: [Formula: see text]
Characterization of A/eq-1 virus isolated during the equine influenza epidemic in India.
Acta virologica    February 1, 1994   Volume 38, Issue 1 25-26 
Singh G.The equine influenza virus, Ludhiana/5/87, isolated from the clinical material during the epidemic of equine influenza in India in 1987 was inhibited in haemagglutination-inhibition test by the antiserum against the prototype A/eq/Prague/1/56 (H7N7) virus and by post-epidemic horse sera. In haemagglutinin and neuraminidase analysis, the A/eq/Ludhiana/5/87 isolate appeared similar to the prototype A/eq/Prague/1/56 virus and was characterized as the H7N7 subtype.
‘Bishoping’ of horses.
The Veterinary record    January 29, 1994   Volume 134, Issue 5 124 doi: 10.1136/vr.134.5.124-a
Kertez P.No abstract available
‘Bishoping’ of horses.
The Veterinary record    January 29, 1994   Volume 134, Issue 5 124 doi: 10.1136/vr.134.5.124-b
Griffiths RB.No abstract available
Adrenocortical carcinoma in a 12-year-old mare.
The Veterinary record    January 29, 1994   Volume 134, Issue 5 113-115 doi: 10.1136/vr.134.5.113
van der Kolk JH, Mars MH, van der Gaag I.A 12-year-old Dutch warmblood mare was examined because it had suffered colic intermittently for a few years and had lost weight in the previous two months. Palpation per rectum revealed a large firm mass in the left sublumbar region; the mass was classified post mortem as an adrenocortical carcinoma. The basal plasma cortisol concentration (at 10.00) of the mare was 94 nmol/litre, within the normal range. As in another case of adrenocortical neoplasm, a functional tumour could not be demonstrated. Only one of the 21 horses with a neoplasm of the pituitary-adrenocortical axis examined by the a...
Sedation of horses with romifidine and butorphanol.
The Veterinary record    January 22, 1994   Volume 134, Issue 4 90-91 doi: 10.1136/vr.134.4.90
Browning AP, Collins JA.Combinations of romifidine and butorphanol were used to sedate 55 horses for a variety of surgical, therapeutic and diagnostic procedures. Eighteen of the horses were given the drugs separately, romifidine first followed by butorphanol four minutes later, and 37 were given the drugs together. The levels of sedation and ataxia were assessed and graded, and there were no statistically significant differences between the two methods of administration. The side effects were typical of the alpha-2 agonists, including bradycardia, heart block and some sweating. Box-walking was observed in one horse....
Update on equine influenza.
The Veterinary record    January 15, 1994   Volume 134, Issue 3 71 doi: 10.1136/vr.134.3.71-b
Mumford JA.No abstract available
Prevalence and factors associated with development of laminitis in horses with duodenitis/proximal jejunitis: 33 cases (1985-1991).
Journal of the American Veterinary Medical Association    January 15, 1994   Volume 204, Issue 2 250-254 
Cohen ND, Parson EM, Seahorn TL, Carter GK.Medical records of 116 horses admitted to the Texas Veterinary Medical Center between Jan 1, 1984 and Dec 31, 1991 with duodenitis/proximal jejunitis (DPJ) were reviewed. The prevalence of laminitis was 28.4% (33/116; 95% confidence interval: 20.2 to 36.6%). The prevalence of DPJ and DPJ-associated laminitis did not appear to vary significantly by year during the study period. Anamnesis, physical examination, clinicopathologic data, and initial treatment recorded at the time of admission were reviewed to determine risk factors associated with development of laminitis associated with DPJ. A tre...
[An outbreak of equine arteritis virus infection in a riding school].
Tijdschrift voor diergeneeskunde    January 15, 1994   Volume 119, Issue 2 30-32 
van Gorkom LP, van Wessum R, van den Hoven R.A major part of the residing horses and ponies of a riding school in Noord-Holland became affected by a febrile disorder that included anorexia, depression, conjunctivitis, urticaria, edema of the legs and laborious locomotion. All remaining horses fell ill within one week. Based on the clinical symptoms the disorder was diagnosed as vasculitis. With serology the causative agent of the disorder appeared to be equine arteritis virus.
Effect of oxytetracycline on metacarpophalangeal and distal interphalangeal joint angles in newborn foals.
Journal of the American Veterinary Medical Association    January 15, 1994   Volume 204, Issue 2 246-249 
Madison JB, Garber JL, Rice B, Stumf AJ, Zimmer AE, Ott EA.Thirty-five newborn foals were assigned to 1 of 3 groups and treated with 0.9% NaCl solution (saline; group 1; n = 12), oxytetracycline (44 mg/kg of body weight; group 2; n = 12), or 2-pyrrolidone (oxytetracycline vehicle; group 3; n = 11) in saline solution during the first 36 hours after birth. Serum biochemical analyses were performed on samples obtained from group-1 and group-2 foals before treatment and 24 and 96 hours after treatment. Lateral to medial radiographic views of the forelimbs were obtained before treatment and 24 and 96 hours after treatment in all foals. Metacarpophalangeal ...
Investigation of the metabolism of azaperone in the horse.
Journal of chromatography    January 14, 1994   Volume 652, Issue 1 23-33 doi: 10.1016/0378-4347(93)e0384-3
Chui YC, Esaw B, Laviolette B.Urine samples collected from a horse after intramuscular administration of 40 mg of azaperone were extracted at pH 10 before and after acid hydrolysis. The extracts were concentrated and analysed by LC-MS-MS. Two N-dealkylated metabolites, N-despyridinylazaperol and N-despyridinylazaperone, and a low concentration of azaperone were detected in the unhydrolysed urine. Six metabolites; hydroxyazaperol, two hydroxyazaperones, azaperol, N-despyridinylazaperol and N-despyridinylazaperone were detected in the hydrolysed urine extracts. Using XAD-2 resin extraction, three glucuronide conjugated azape...
Genetics of racing performance in the Japanese Thoroughbred horse:: I. Description of the data.
Journal of animal breeding and genetics = Zeitschrift fur Tierzuchtung und Zuchtungsbiologie    January 12, 1994   Volume 111, Issue 1-6 121-127 doi: 10.1111/j.1439-0388.1994.tb00445.x
Oki H, Willham RL, Sasaki Y.The Japan Racing Association (JRA) operates 10 national racecourses with both turf and dirt tracks. JRA formulates the rules for horseracing; registers owners, colors, and horses using foal registration; and licenses all JRA trainers and jockeys. In 1990, at the 10 racecourses there were 288 racing days, 3,353 races, and some 38,397 horses. Horse breeding is concentrated in 7 locations with 93% of the Thoroughbreds foaled each year coming from Hokkaido. Thoroughbred flat racing comprise 92% of all races held. Two year olds race together and nearly 40% of their races are run at 1200 m. Some 39%...