Equine health encompasses the study and management of diseases, disorders, and overall well-being of horses. It involves understanding various physiological systems, preventive care, and treatment strategies to maintain optimal health in equine populations. Common areas of focus include nutrition, infectious diseases, orthopedic conditions, and reproductive health. Research in equine health aims to advance knowledge on diagnostic methods, therapeutic interventions, and management practices that improve horse welfare and performance. This page collects peer-reviewed research studies and scholarly articles that explore the diverse aspects of equine health, offering insights into current findings and advancements in the field.
Smith JS, Mayhew IG.The sympathetic nervous innervation of the head was surgically transected in the horse, cow, sheep and goat. The site of transection was preganglionic in all 4 species and ganglionic-postganglionic in 2 additional horses. The Horner's syndrome, manifested as a result of the iatrogenic lesion, varied with the species. Ptosis was the most constant sign in all species. Unilateral sweating over the face and proximal neck, particularly at the base of the ear, was the most prominent feature in the horse. The cow revealed distension of vasculature and cutaneous heat of the pinna, and a reduced produc...
Duncan ID, Baker GJ, Heffron CJ, Griffiths IR.The larynges of 6 horses were examined endoscopically and the findings correlated with the gross and histological appearance of the intrinsic laryngeal muscles and their nerve supply. In all cases it appeared that the balance between abductor and adductor muscle groups had been lost due to preferential atrophy of individual muscles or groups of muscles. The laryngeal abnormalities recorded were asymmetry of the larynx with asynchronous left sided abduction and fluttering or trembling of the left vocal cord and arytenoid cartilage. It is suggested that these changes represent the early signs of...
Zakin MM, Peña C, Poskus E, Stewart JM, Paladini AC.The immunological properties of a synthetic human growth hormone fragment comprising the amino acids 73 through 128 and of the homologous natural horse growth fragment formed by amino acids 73 through 123, have been comparatively studied. Antisera obtained in rabbits inoculated with the native human hormone or with the fragments, were used. By hemagglutination experiments both fragments have the same reactivity toward the anti-human growth hormone serum, but complement fixation curves detect the existence of at least two populations of antibodies presumably originated against the sequence 73-1...
Böhm D, Waibl H.Of 28 fractures of the first phalanx 21 were treated with osteosynthesis; one was treated conservatively. 2 to 4 compression screws have been applied, while the distal part of the limb was immobilized by a light cast bandage for 8 days. The implants were removed 2 to 3 months post operationem. All patients are again used in sports.
Sumner-Smith G, Bell M, Manley P, Caddell E, Hoare J.The advances made by the use of a telemetric system in the study of bone strain in a free-moving horse are reported. A rosette strain gauge was bonded to the craniomedial aspect of the metacarpus of the horse. Attachment of a miniature FM transmitter to lead wires facilitated telemetric transmission of of resistance changes which corresponded to limb movement. During 3 different gaits, the trace pattern remained similar, although frequency and amplitude varied. The tracings were similar to those reported in other species in which nontelemetric transmission was used.
Mahoney DF, Wright IG, Frerichs WM, Groenendyk S, O'Sullivan BM, Roberts MC, Waddell AH.A Babesia parasite, isolated from the blood of a horse at Bowral, New South Wales, was identified on the basis of its morphological features, host specificity and serological reactions, as Babesia equi (Laveran 1901). The case was originally reported by Churchill and Best (1976, Aust. vet. J. 52: 487) and is the first record of equine babesiosis in Australia. In preliminary studies, the organism produced only a mild disease in an intact horse, but caused the typical clinical syndrome of acute babesiosis in a splenectomised horse, which died 19 days after the intravenous inoculation of the para...
Gerber JD, Marron AE, Bass EP, Beckenhauer WH.The cell-mediated immune response and antibody response of horses of varying ages and of pregnant horses to equine herpesvirus 1 antigen were examined. Six to eight month old horses showed either no increase or slight increases in anti-equine herpesvirus 1 serum neutralizing antibody following vaccination and revaccination with a modified live equine herpesvirus 1 vaccine. However, these same horses showed a marked increase in the cell-mediated immune response to equine herpesvirus 1 as measured by the lymphocyte transformation test. Eighteen to 21 month old horses showed four to 64-fold incre...
Cazalet E.The paper examines the responsibilities of the veterinary surgeon in relation to the advances more recently made in the field of equine cardiology. Notwithstanding such advances it is stated that the normal established legal principles apply, in particular in relation to the preparation of certificates, namely that the veterinary surgeon must be sufficiently expert to give the opinion sought, that he must make himself fully aware of the purpose for which the certificate is required and that he must make clear the nature and limitations of any examination carried out.
Roberts MC.Progressive leukaemic changes and a persistent anaemia were demonstrated in the blood of a 7 year old gelding, which had shown early signs of lowered performance and unthriftiness, and later developed dependent oedema and became dull and listless. The total leucocyte count, initially within the normal range although reflecting an absolute lymphocytosis, increased fourfold in 6 days from excessive lymphoid production involving predominantly the more immature cell types; lymphoblasts, prolymphocytes and large lymphocytes. The severity of the condition was confirmed by bone marrow biopsy.
Greatorex JC.The clinical manifestations, diagnosis and differential diagnosis of "verminous aneurysm" formation at the root of the cranial mesenteric artery and coeliac artery resulting from Strongylus vulgaris larvae migration are described. Forty-nine of 57 cases were successfully treated with low molecular weight dextran (dextran 70).
Snow DH.Using adrenergic agonists and antagonists this study has demonstrated that adrenaline induced sweating is mediated via beta2-adrenoreceptors in the horse.
Knight HD, Costner GC.During the summer and fall of 1973, a few horses, goats, and cattle in the Napa Valley of California became intoxicated by bromide via the ingestion of volunteer oat hay that had been cut from a field treated with methyl bromide, a soil fumigant. The bromide content of the hay ranged from 6,00 to 8,400 ppm. Signs of intoxication were lethargy, weakness, and ataxia. Animals experimentally fed the contaminated hay developed signs of intoxication between the 7th and 9th days.
Farrell RK, Hilbert BJ.Methods of equine identification including signalment, blood typing tattooing and freeze marking are discussed. A new system of individually identifying horses with an unalterable freeze mark is proposed. Unalterable numerical and alphabetical symbols have been developed to apply a registration number to the animal.
Dyson DA, Smith GR.When incorporated in solid medium at a concentration of 15 per cent, the defibrinated blood of certain horses strongly suppressed the growth of some, but not all, strains of Mycoplasma mycoides subsp mycoides so that many colonies failed to develop to a visible size. Blood from a single rabbit was tested and found to exert a similar effect. There was striking variation in the degree of inhibition produced by different samples of horse blood and, of five strains of the organism examined, the T1 vaccine strain was the most susceptible. The results suggested that the effect was not due to antibod...
Myers J.At the outbreak of equine influenza (EI) we chose to close our horse-based business, as we did not want to risk our horses contracting the disease and the demand for our services ceased. We report our experiences of the outbreak.
Webb PD, Steven DH.The adrenal cortex from twelve fetal foals (gestational ages from 61 to 300 days) was examined by light and electron microscopy. Adrenal glands from three newborn foals were also examined by light microscopy. Between 61 and 100 days of gestation the adrenal cortex became organised into two distinct regions, the zona glomerulosa and zona fasciculata, which grew steadily in thickness until the 300th day. Between 300 days and birth there was a dramatic increase in the width of the zona fasciculata. From 200 days a narrow band of compact cells marked the cortico-medullary border. Though these cell...
Brown MP, Kelly RH, Gronwall RR, Stover SM.Six healthy adult mares were given a single IV dose (25 mg/kg of body weight) of chloramphenicol sodium succinate. Chloramphenicol concentrations in serum, synovial fluid, peritoneal fluid, and urine were measured serially over a 48-hour period. The highest measured serum chloramphenicol concentration was 6.21 micrograms/ml at 0.5 hour. Chloramphenicol was detected in synovial and peritoneal fluids, with mean peak concentrations of 3.89 micrograms/ml and 3.50 micrograms/ml, respectively, at 0.5 hour. Serum and synovial concentrations declined rapidly and were not measurable at 3 hours. Chloram...
Adland-Davenport P, Brown MP, Robinson JD, Derendorf HC.Fourteen foals less than four days of age were treated with the aminoglycoside, amikacin sulphate, and either penicillin or ampicillin for septicaemia, pneumonia, and/or failure of passive immunoglobulin transfer. Serum amikacin concentrations were determined at three times during an 8 or 12 h dosing interval. A 7.0 mg/kg bodyweight dose of amikacin every 8 h was appropriate. Prematurity did not influence mortality. All seven premature foals survived, whereas four of the seven full term foals died. Uraemia in three foals was caused by urinary bladder rupture; amikacin-induced nephrotoxicity wa...
Cerullo M, Driessen B, Douglas H, Hopster K. In anesthetized adult horses, changes in recumbency can influence the cardiovascular system but how arterial blood pressures and oxygen tension change in isoflurane anesthetized animals as a direct result of hoisting has not been investigated. To evaluate effects of hoisting on hemodynamic function and pulmonary gas exchange in isoflurane-anesthetized horses. Prospective, experimental study. Six adult horses were anesthetized three times using isoflurane in pure oxygen (inspired fraction 0.9-1.0), and allowed breathing spontaneously in lateral recumbency. After 45 min horses were hoisted u...
Hyland JH, Langsford DA.Foetal death was induced in 10 Standardbred mares at day 45 of gestation by injecting 20 to 45 ml of hypertonic (24% W/V) saline into the conceptus at surgery. Ten mares underwent sham treatment and acted as controls. Blood and urine samples were collected every other day between days 30 and 45 post ovulation and at 0, 3 and 6 h relative to the infusion of saline in the treated mares, or sham treatment in control mares. Blood and urine samples were then collected daily between days 46 and 55 post ovulation. Urine oestrone sulphate (E1S) concentrations, measured by radioimmunoassay, increased b...
Sievert M, Schuler G, Wehrend A.Due to the time-limited intestinal uptake of colostral immunoglobulins, the suggested treatment of hypogammaglobulinemia in new-born foals is usually plasma transfusion. The aims of this study were twofold: firstly, to investigate the course of serum IgG concentration after plasma transfusion in newborn foals; and secondly, to determine the amount of transfusion required for a significant increase in serum IgG concentration. For this purpose, the IgG concentration was measured in 23 foals at three different points in time: before transfusion, 1 hour after transfusion, and 24 hours after transf...
Weiss DJ, Evanson OA, McClenahan D, Fagliari J, Walcheck B.To determine whether platelets become activated and form platelet-platelet or platelet-neutrophil aggregates, or both, when subjected to shear. Methods: Blood obtained from 3 Thoroughbreds. Methods: Blood, with PCV adjusted to 32 (low hematocrit) or 60 (high hematocrit)%, was subjected to shear rates of 11.25, 22.5, 45, 90, 225, and 750/s for 3 minutes by use of a cone-plate viscometer. Flow cytometric techniques were used to identify activated platelets, platelet-platelet aggregates, and platelet-neutrophil aggregates. Results: Shear resulted in decreased platelet count, increased mean platel...
Drudge JH, Lyons ET, Tolliver SC.The basic-dose confirmation tests of tioxidazole for removal of susceptible populations of gastrointestinal parasites of the horse were made in 10 naturally infected horses, using the critical test method (experiment A). A single dose of toxidazole, given at the rate of 11 mg/kg of body weight, was administered to 5 horses by stomach tube and to 5 horses by mixing the drug with the daily grain ration. In the 5 horses given the drug by stomach tube, aggregate average removals were 90% or more for 5 horses infected with Stronglyus vulgaris, 5 infected with S edentatus, 5 infected with small stro...
Claerhoudt S, Pille F, Vanderperren K, Hauspie S, Duchateau L, Van der Vekens E, Saunders JH.To investigate whether in navicular bones (NB) from warmbloods, distal border fragmentation is associated with the shape of the proximal articular border or other radiological findings. Methods: Radiographs of the front feet of 325 normal, subadult horses presented for admission as breeding stallions were reviewed. Results: The proximal articular border of the total of 650 NB was classified as straight (n = 278), convex (n = 184), undulating (n = 147) or concave (n = 41). Distal border fragments were present in 57 NB (8.8%). They were significantly more prevalent in NB with a concave (9/41; 22...
Tamin A, Rota PA.Hendra virus (HeV) and Nipah virus (NiV) are the causative agents of emerging transboundary animal disease in pigs and horses. They also cause fatal disease in humans. NiV has a case fatality rate of 40 - 100%. In the initial NiV outbreak in Malaysia in 1999, about 1.1 million pigs had to be culled. The economic impact was estimated to be approximately US$450 million. Worldwide, HeV has caused more than 60 deaths in horses with 7 human cases and 4 deaths. Since the initial outbreak, HeV spillovers from Pteropus bats to horses and humans continue. This article presents a brief review on the cur...
Gallagher K, Stowe HD.Blood samples were obtained from 45 racing Standardbred horses immediately before and immediately after a training jog at a commercial race track to establish reference values for serum selenium and related values of the peroxide reduction system of racing horses. Hemoglobin, hematocrit, and serum selenium increased significantly (P < 0.001), whereas RBC-reduced glutathione decreased significantly (P < 0.01) immediately after exercise. Glutathione peroxidase and glutathione reductase were not altered by exercise. Serum copper and magnesium were significantly increased (P < 0.01) after exercise...
Tulleners EP, Becht JL, Richardson DW, Divers TJ.Obstructive choledocholithiasis in a 12-year-old mare was corrected surgically by choledocholithotripsy. The mare had a history of chronic weight loss, intermittent fever, partial anorexia, jaundice, recurrent abdominal pain, and an abdominal mass palpable per rectum. Values for alkaline phosphatase, bilirubin, gamma-glutamyl transferase, sorbitol dehydrogenase, and bromsulpthalein half-life were increased and bilirubinuria was evident before surgery. Two liver biopsies revealed periportal and portal fibrosis, bile duct proliferation, cholestasis, and variable amounts of hepatocellular necrosi...
Beroza GA.In horses, ventral laryngotomies are typically allowed to heal by second intention. Partial closure of the laryngotomy incision, however, was associated wtih less exudate, less aftercare, shorter hospitalization, and better cosmetic results, compared with the traditional technique. The partial closure technique did not result in complications in the 3 horses in which it was attempted.
Mason TA.A case of bicipital bursitis in a six-year-old mare is described. The horse was presented with acute lameness, pyrexia and hot swelling over the right shoulder region. Although antibiotic treatment relieved these signs, a firm cold swelling remained which had to be removed by surgical resection and drainage.
Timofeev BA, Bolotin IM, Stepanova LP, Bogdanov AA, Georgiu Kh, Malyshev SN, Petrovskiĭ , Klibanov AL, Torchilin VP.The cultures of Nuttalia eque mainly develop in the reticuloendothelial organs and so in treatment of nuttaliosis in horses and the Nuttalia carriers diamidine, an analog of imidocarb or imidozoline, was used encapsulated in liposomes. The liposomes were prepared with a modification of the phase inversion method (the lipids were dissolved in a mixture of freon-11 and chloroform). The content of the organic solvents in the preparation, as evidenced by gas liquid chromatography, was less than 0.2 per cent. The main fraction consisted of particles 1.5 to 2.5 microns in diameter. The tests on anim...