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Topic:Equine Health

Equine health encompasses the study and management of diseases, disorders, and overall well-being of horses. It involves understanding various physiological systems, preventive care, and treatment strategies to maintain optimal health in equine populations. Common areas of focus include nutrition, infectious diseases, orthopedic conditions, and reproductive health. Research in equine health aims to advance knowledge on diagnostic methods, therapeutic interventions, and management practices that improve horse welfare and performance. This page collects peer-reviewed research studies and scholarly articles that explore the diverse aspects of equine health, offering insights into current findings and advancements in the field.
Use of continuous positive airway pressure (CPAP) to optimise oxygenation in anaesthetised horses–a clinical study.
Equine veterinary journal    December 19, 2012   Volume 45, Issue 4 414-418 doi: 10.1111/evj.12011
Mosing M, Rysnik M, Bardell D, Cripps PJ, MacFarlane P.Hypoxaemia is a common problem during equine anaesthesia. Continuous positive airway pressure (CPAP) is a ventilation mode routinely employed in man to overcome hypoxaemia but has not been objectively assessed in horses. Objective: To test the effects of CPAP on oxygenation and its indices in anaesthetised horses in a clinical setting. Methods: Twenty-four healthy horses requiring anaesthesia in dorsal recumbency were anaesthetised using a standard protocol. Following orotracheal intubation and connection to an anaesthetic machine capable of applying CPAP, horses were randomly allocated to ven...
Retrospective evaluation of facilitated pastern ankylosis using intra-articular ethanol injections: 34 cases (2006-2012).
Equine veterinary journal    December 19, 2012   Volume 45, Issue 4 442-447 doi: 10.1111/evj.12012
Caston S, McClure S, Beug J, Kersh K, Reinertson E, Wang C.While surgical arthrodesis is the treatment of choice for osteoarthritis of the proximal interphalangeal joint, some clients are unable to pursue surgery due to costs. A more economical technique was sought using intra-articular ethyl alcohol injections to facilitate ankylosis. Objective: To describe the technique and outcome of intra-articular ethyl alcohol injections for facilitated ankylosis of proximal interphalangeal joints with osteoarthritis. Methods: As a retrospective case series, the medical records (2006-2012) of clinical cases diagnosed with proximal interphalangeal joint osteoarth...
Multiple secretoglobin 1A1 genes are differentially expressed in horses.
BMC genomics    December 19, 2012   Volume 13 712 doi: 10.1186/1471-2164-13-712
Côté O, Lillie BN, Hayes MA, Clark ME, van den Bosch L, Katavolos P, Viel L, Bienzle D.Secretoglobin 1A1 (SCGB 1A1), also called Clara cell secretory protein, is the most abundantly secreted protein of the airway. The SCGB1A1 gene has been characterized in mammals as a single copy in the genome. However, analysis of the equine genome suggested that horses might have multiple SCGB1A1 gene copies. Non-ciliated lung epithelial cells produce SCGB 1A1 during inhalation of noxious substances to counter airway inflammation. Airway fluid and lung tissue of horses with recurrent airway obstruction (RAO), a chronic inflammatory lung disease affecting mature horses similar to environmental...
Physiological and behavioral responses of horses during police training.
Animal : an international journal of animal bioscience    December 17, 2012   Volume 7, Issue 5 822-827 doi: 10.1017/S1751731112002327
Munsters CC, Visser EK, van den Broek J, Sloet van Oldruitenborgh-Oosterbaan MM.Mounted police horses have to cope with challenging, unpredictable situations when on duty and it is essential to gain insight into how these horses handle stress to warrant their welfare. The aim of the study was to evaluate physiological and behavioral responses of 12 (six experienced and six inexperienced) police horses during police training. Horses were evaluated during four test settings at three time points over a 7-week period: outdoor track test, street track test, indoor arena test and smoke machine test. Heart rate (HR; beats/min), HR variability (HRV; root means square of successiv...
Equine pathology for the surgical pathologist.
International journal of surgical pathology    December 17, 2012   Volume 21, Issue 2 146 doi: 10.1177/1066896912470164
Coyne JD.No abstract available
Forces applied with a hoof tester to cadaver feet vary widely between users.
The Veterinary record    December 15, 2012   Volume 172, Issue 7 182 doi: 10.1136/vr.101049
Arndt JL, Pfau T, Day P, Pardoe C, Bolt DM, Weller R.Hoof testers are commonly used in equine practice. In this study, we determined the intraoperator and interoperator reliability of force application with hoof testers for different groups: experienced veterinarians, novices and farriers. For this purpose, we have developed and validated an instrumented hoof tester. Forces varied significantly between the different regions of the foot for experienced operators applying the highest forces to the heels, then the frog, then the toe, and the lowest forces to the quarters. Novices applied significantly more force to the toe versus the frog. Intraope...
Risk factors associated with cast complications in horses: 398 cases (1997-2006).
Journal of the American Veterinary Medical Association    December 14, 2012   Volume 242, Issue 1 93-98 doi: 10.2460/javma.242.1.93
Janicek JC, McClure SR, Lescun TB, Witte S, Schultz L, Whittal CR, Whitfield-Cargile C.To determine the frequency of and risk factors for complications associated with casts in horses. Methods: Multicenter retrospective case series. Methods: 398 horses with a half-limb or full-limb cast treated at 1 of 4 hospitals. Methods: Data collected from medical records included age, breed, sex, injury, limb affected, time from injury to hospital admission, surgical procedure performed, type of cast (bandage cast [BC; fiberglass tape applied over a bandage] or traditional cast [TC; fiberglass tape applied over polyurethane resin-impregnated foam]), limb position in cast (flexed, neutral, o...
Use of antibody titers measured via serum synergistic hemolysis inhibition testing to predict internal Corynebacterium pseudotuberculosis infection in horses.
Journal of the American Veterinary Medical Association    December 14, 2012   Volume 242, Issue 1 86-92 doi: 10.2460/javma.242.1.86
Jeske JM, Spier SJ, Whitcomb MB, Pusterla N, Gardner IA.To estimate likelihood ratios (LRs) of correctly identifying internal Corynebacterium pseudotuberculosis infection in horses by measurement of antibody titers via serum synergistic hemolysis inhibition (SHI) testing. Methods: Retrospective case-control study. Methods: 170 horses (171 records; 92 cases of C pseudotuberculosis infection and 79 controls). Methods: Medical records were reviewed, and horses were grouped on the basis of evidence of internal or external C pseudotuberculosis infection. The LRs and 95% confidence intervals for identification of internal C pseudotuberculosis infection b...
Comparison of the use of scapular ultrasonography, physical examination, and measurement of serum biomarkers of bone turnover versus scintigraphy for detection of bone fragility syndrome in horses.
Journal of the American Veterinary Medical Association    December 14, 2012   Volume 242, Issue 1 76-85 doi: 10.2460/javma.242.1.76
Arens AM, Puchalski SM, Whitcomb MB, Bell R, Gardner IA, Stover SM.To define scintigraphic, physical examination, and scapular ultrasonographic findings consistent with bone fragility syndrome (BFS) in horses; develop indices of BFS severity; and assess accuracy of physical examination, scapular ultrasonography, and serum biomarkers for BFS diagnosis. Methods: Prospective case-control study. Methods: 48 horses (20 horses with BFS and 28 control horses). Methods: Horses underwent forelimb scintigraphic evaluation, physical examination, scapular ultrasonography, and serum collection. Scintigraphy was used as a reference standard to which physical examination, s...
Evaluation of regional limb perfusion with erythromycin using the saphenous, cephalic, or palmar digital veins in standing horses.
Journal of veterinary pharmacology and therapeutics    December 14, 2012   Volume 36, Issue 5 434-440 doi: 10.1111/jvp.12028
Kelmer G, Martin-Jimenez T, Saxton AM, Catasus C, Elliot SB, Lakritz J.There are no reported studies evaluating the use of erythromycin for regional limb perfusion (RLP) in horses. Our hypothesis was that using the cephalic and saphenous veins for RLP will enable delivery of therapeutic concentrations of erythromycin to the distal limb. Nineteen healthy horses participated in the study. The cephalic, saphenous or palmar digital (PD) vein was used to perfuse the limb with erythromycin. Synovial samples were collected from the metacarpo/metatarso-phalangeal (MCP/MTP) joint and blood samples were collected from the jugular vein. Maximum concentration (C(max)) of ery...
Cutaneous neoplastic lesions of equids in the central United States and Canada: 3,351 biopsy specimens from 3,272 equids (2000-2010).
Journal of the American Veterinary Medical Association    December 14, 2012   Volume 242, Issue 1 99-104 doi: 10.2460/javma.242.1.99
Schaffer PA, Wobeser B, Martin LE, Dennis MM, Duncan CG.To identify epidemiological trends in cutaneous neoplasms affecting equids in central North America and compare them with previously reported trends. Methods: Retrospective case series. Methods: 3,351 cutaneous biopsy specimens from 3,272 equids with a neoplastic diagnosis. Methods: Diagnostic reports from 2 diagnostic laboratories (Colorado State University and Prairie Diagnostic Services Inc) were reviewed for frequency of specific lesions and epidemiological trends. Variables included in analyses (if known) were age, sex, breed, geographic location, date of diagnosis, location of neoplasm o...
Chronic subdural hematomas and the elderly: Surgical results from a series of 125 cases: Old “horses” are not to be shot!
Surgical neurology international    December 14, 2012   Volume 3 150 doi: 10.4103/2152-7806.104744
de Araújo Silva DO, Matis GK, Costa LF, Kitamura MA, de Carvalho Junior EV, de Moura Silva M, Barbosa BJ, Pereira CU, da Silva JC, Birbilis TA....To present the accumulated experience from treating chronic subdural hematomas (CSDH) in a local hospital of a third world country. Methods: One hundred and twenty-five consecutive patients with CSDH who were surgically treated in the Neurosurgical Department of the Hospital da Restauração, Recife-PE, Brazil, between January 2006 and May 2008, were retrospectively studied. Glasgow Outcome Scale (GOS) was employed to define outcome at 6 months as good (GOS 4 and 5) or poor (GOS ≤ 3). Age, admission Glasgow Coma Scale (GCS), location of hematomas (unilateral/bilateral), drainage system place...
Misoprostol: is it safety or a lack of understanding that prevents its more frequent usage?
Equine veterinary journal    December 13, 2012   Volume 45, Issue 1 8 doi: 10.1111/evj.12017
Blikslager AT.No abstract available
Comparative pharmacokinetics of desfuroylceftiofur acetamide after intramuscular versus subcutaneous administration of ceftiofur crystalline free acid to adult horses.
Journal of veterinary pharmacology and therapeutics    December 13, 2012   Volume 36, Issue 3 309-312 doi: 10.1111/jvp.12030
Fultz L, Giguère S, Berghaus LJ, Davis JL.No abstract available
Exploration of global gene expression changes during the estrous cycle in equine endometrium.
Biology of reproduction    December 13, 2012   Volume 87, Issue 6 136 doi: 10.1095/biolreprod.112.103226
Gebhardt S, Merkl M, Herbach N, Wanke R, Handler J, Bauersachs S.The equine endometrium exhibits characteristic morphological and functional changes during the estrous cycle controlled by the interplay of progesterone and estradiol. A microarray analysis of endometrial tissue samples derived from five time points of the estrous cycle (Day [D] 0, D3, D8, D12, and D16) was performed to study the dynamics of equine endometrial gene expression. Statistical analysis revealed 4996 genes differentially expressed during the estrous cycle. Clustering of similar expression profiles was performed to find groups of coregulated genes. This revealed eight major profiles:...
Outcome after arthroscopic treatment of lateral femoral trochlear ridge osteochondrosis in sport horses. A retrospective study of 37 horses.
Veterinary and comparative orthopaedics and traumatology : V.C.O.T    December 13, 2012   Volume 26, Issue 2 105-109 doi: 10.3415/VCOT-11-12-0182
UpRichard K, Elce YA, Piat P, Beauchamp G, Laverty S.To determine the short- and long-term outcome for sport horses after arthroscopic treatment of osteochondrosis of the lateral trochlear ridge of the femur. Methods: A retrospective study was performed using the medical records of horses intended for use as English sport horses. Outcome was obtained through telephone questionnaire. Results: Thirty-seven horses, mainly Warmbloods, underwent arthroscopic surgery for treatment of lateral femoral trochlear ridge osteochondrosis. Short-term outcome revealed that 27 of 37 horses had no complications. Seven horses had postoperative lameness and effusi...
The equine endometrial cup reaction: a fetomaternal signal of significance.
Annual review of animal biosciences    December 13, 2012   Volume 1 419-442 doi: 10.1146/annurev-animal-031412-103703
Antczak DF, de Mestre AM, Wilsher S, Allen WR.A remarkable feature of equine pregnancy is the development of the invasive trophoblast of the chorionic girdle and its formation of the gonadotrophin-secreting endometrial cup cells in early gestation. The details of this process have been revealed only slowly over the past century, since the first description of the endometrial cups in 1912. This centennial presents an opportunity to review the characteristics of the cells and molecules involved in this early, critical phase of placentation in the mare. The invasiveness of the chorionic girdle trophoblast appears to represent an atavistic at...
Robot-assisted surgery: searching for the pony.
Journal of endourology    December 13, 2012   Volume 26, Issue 12 1540-1541 doi: 10.1089/end.2012.1554
Menon M.No abstract available
Reducing injuries in racehorses: mission impossible?
Equine veterinary journal    December 13, 2012   Volume 45, Issue 1 6-7 doi: 10.1111/evj.12009
Verheyen KL.No abstract available
Case-control study of high-speed exercise history of Thoroughbred and Quarter Horse racehorses that died related to a complete scapular fracture.
Equine veterinary journal    December 13, 2012   Volume 45, Issue 3 284-292 doi: 10.1111/j.2042-3306.2012.00644.x
Vallance SA, Entwistle RC, Hitchens PL, Gardner IA, Stover SM.Identification of exercise history patterns that are related to catastrophic scapular fracture will facilitate prevention of racehorse fatalities. Objective: To determine if exercise patterns are associated with scapular fracture in Thoroughbred (TB) and Quarter Horse (QH) racehorses. Methods: High-speed exercise histories for 65 TB and 26 QH racehorses that had a complete scapular fracture (cases) and 2 matched control racehorses were retrospectively studied. Exercise variables were created from lifetime race and official timed workout reports. Associations between exercise variables and scap...
Science in brief: Interactions between the rider, the saddle and the horse.
Equine veterinary journal    December 13, 2012   Volume 45, Issue 1 3-4 doi: 10.1111/evj.12006
Clayton HM.No abstract available
Acid-base indicators in the venous and arterial blood of horses affected by recurrent airway obstruction (RAO).
Polish journal of veterinary sciences    December 12, 2012   Volume 15, Issue 3 463-467 doi: 10.2478/v10181-012-0071-x
Stopyra A, Sobiech P, Waclawska-Matyjasik A.The acid-base equilibrium is closely linked to gas exchange in the lungs, and respiratory exchange ratios are used to evaluate respiratory effectiveness and tissue oxygen levels. Acid-base indicators are determined in both arterial and venous blood samples. This study compares the usefulness of acid-base indicators of venous and arterial blood in monitoring the condition of horses with recurrent airway obstruction. Prior to treatment involving bronchodilating glucocorticoids, expectorant and mucolytic drugs, more pronounced changes were observed in venous blood (pH 7.283, pCO2 61.92 mmHg, pO2 ...
Histopathological features in subsequent muscle biopsies in a warmblood mare with myotonic dystrophy.
The veterinary quarterly    December 12, 2012   Volume 32, Issue 3-4 187-192 doi: 10.1080/01652176.2012.749548
Ludvikova E, Lukas Z, Vondracek P, Jahn P.No abstract available
Identification of protoxins and a microbial basis for red maple (Acer rubrum) toxicosis in equines. Agrawal K, Ebel JG, Altier C, Bischoff K.The leaves of Acer rubrum (red maple), especially when wilted in the fall, cause severe oxidative damage to equine erythrocytes, leading to potentially fatal methemoglobinemia and hemolytic anemia. Gallic acid and tannins from A. rubrum leaves have been implicated as the toxic compounds responsible for red maple toxicosis, but the mechanism of action and toxic principle(s) have not been elucidated to date. In order to investigate further how red maple toxicosis occurs, aqueous solutions of gallic acid, tannic acid, and ground dried A. rubrum leaves were incubated with contents of equine ileum,...
What is your diagnosis? Bilateral SDFT rupture.
Journal of the American Veterinary Medical Association    December 12, 2012   Volume 241, Issue 12 1563-1564 doi: 10.2460/javma.241.12.1563
Levine RS, Pacheco AP, Chope K, García López JM, Gates S, Costa LR.No abstract available
Clinical use of antimicrobial regional limb perfusion in horses: 174 cases (1999-2009).
Journal of the American Veterinary Medical Association    December 12, 2012   Volume 241, Issue 12 1650-1658 doi: 10.2460/javma.241.12.1650
Rubio-Martínez LM, Elmas CR, Black B, Monteith G.To describe the clinical use of regional limb perfusion with antimicrobials (A-RLP), complications, and outcome in a large series of patients. Methods: Retrospective case series. Methods: 174 horses. Methods: Medical records of horses treated with A-RLP between 1999 and 2009 were reviewed. Signalment, primary complaint, horse use, etiology, duration of clinical signs, previous treatment, structures involved, concurrent conditions, A-RLP characteristics, additional treatments, complications, and outcome were recorded. At long-term follow-up, 2 outcomes were investigated: survival rate and retur...
How do metacarpophalangeal joint extension, collateromotion and axial rotation influence dorsal surface strains of the equine proximal phalanx at different loads in vitro?
Journal of biomechanics    December 12, 2012   Volume 46, Issue 4 738-744 doi: 10.1016/j.jbiomech.2012.11.028
Singer E, Garcia T, Stover S.The biomechanical circumstances that promote sagittal fracture of the equine proximal phalanx (P1) are poorly understood. In order to improve our understanding of equine metacarpophalangeal joint (MCPJ) biomechanics and potential aetiologies of sagittal P1 fractures, the study objectives were to quantify P1 bone strains, collateromotion and axial rotation during MCPJ extension under controlled loading circumstances. Unilateral limbs from six cadavers were instrumented with bone reference markers for measurement of P1 movement relative to third metacarpal bone positions during axial limb loadin...
The examination of biophysical parameters of skin (transepidermal water loss, skin hydration and pH value) in different body regions of ponies.
Polish journal of veterinary sciences    December 12, 2012   Volume 15, Issue 3 553-559 doi: 10.2478/v10181-012-0081-8
Szczepanik MP, Wilkołek PM, Pluta M, Adamek ŁR, Pomorski ZJ.The purpose of this study was to evaluate transepidermal water loss, skin hydration and skin pH in normal ponies. Sixteen ponies of both sexes were examined in the study. Measurements were taken from seven different sites: the neck region, the shoulder, thorax, lumbar, inguinal, lip region and the auricle. In each of the regions transepidermal water loss (TEWL), skin hydration and skin pH were measured. For transepidermal water loss, the lowest values were observed in the lumbar region (9.71g/hm2), while the highest values were observed in the lip region (22.35 g/hm2). In the case of skin hydr...
Thrombelastographic characterization of coagulation/fibrinolysis in horses: role of carboxyheme and metheme states.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis    December 12, 2012   Volume 24, Issue 3 273-278 doi: 10.1097/MBC.0b013e32835bfd6e
Olver CS, Nielsen VG.Carboxyheme and metheme states modulate hemostasis in humans and other species. Further, carbon monoxide and/or nitric oxide production increase in inflammatory disorders involving the gastrointestinal tract, with associated hypercoagulability or hypocoagulability. In particular, the horse suffers both thrombotic or coagulopathic complications during acute gastrointestinal disease. This investigation characterized the thrombelastographic response to carboxyheme (via CORM-2) or metheme (via phenylhydroxylamine, PHA) states without/with addition of tissue type plasminogen activator. Citrated pla...
Serological evidence for infections with Borna disease virus in Turkey.
Berliner und Munchener tierarztliche Wochenschrift    December 12, 2012   Volume 125, Issue 11-12 452-455 
Yeşilbağ K, Herzog S, Kennerman E, Tuncer P, Schmid S, Kaya G, Thiel HJ.Distribution of Borna disease virus (BDV) infection outside endemic areas has been studied in several countries. We examined serum samples for anti-BDV antibodies in purebred racing horses and other domestic animals in Turkey. In total serum samples of 437 animals including 282 horses, 50 sheep, 25 goats, 50 cattle, and 30 cats were tested by indirect immunofluorescence assay (IFA). Anti-BDV antibodies were detected in 4.9% of horses, 12% of sheep, 4% of goats, 14% of cattle and 6.6% of cats. No statistical difference was observed between seroprevalence in Arabic and English purebred horses fr...