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Topic:Equine Health

Equine health encompasses the study and management of diseases, disorders, and overall well-being of horses. It involves understanding various physiological systems, preventive care, and treatment strategies to maintain optimal health in equine populations. Common areas of focus include nutrition, infectious diseases, orthopedic conditions, and reproductive health. Research in equine health aims to advance knowledge on diagnostic methods, therapeutic interventions, and management practices that improve horse welfare and performance. This page collects peer-reviewed research studies and scholarly articles that explore the diverse aspects of equine health, offering insights into current findings and advancements in the field.
Status of natural infection with Japanese encephalitis virus in Japan: prevalence of antibodies to the nonstructural 1 protein among humans and horses.
Vaccine    September 30, 2009   Volume 27, Issue 50 7129-7130 doi: 10.1016/j.vaccine.2009.09.052
Konishi E.The literature on natural infections with Japanese encephalitis virus in Japan and subclinical:clinical infection rates was summarized. To detect natural infections, conventional serologic methods were used in the past, while nonstructural 1 protein-based methods have been used recently. Annual infection rates in humans and horses indicated the status of natural virus activity in Japan.
Functional relationships among intrafollicular insulin-like growth factor 1, circulatory gonadotropins, and development of the dominant follicle in mares.
Animal reproduction science    September 30, 2009   Volume 118, Issue 2-4 270-278 doi: 10.1016/j.anireprosci.2009.09.002
Checura CM, Beg MA, Parrish JJ, Ginther OJ.The functional relationships among intrafollicular free insulin-like growth factor 1 (IGF1), circulatory gonadotropins, and development of the dominant follicle were studied in 40 mares in two experiments. A GnRH antagonist (Acyline) was given i.m. at the expected beginning of follicular deviation (largest follicle or F1> or =20mm; Day 0) alone (Acyline group) or in combination with intrafollicular treatment of F1 with rhIGF1 (Acyline/IGF1 group). In Experiment 1, blood samples, follicular-fluid samples, and diameter of F1 were taken on Days 1 and 2. In Experiment 2, daily follicular diamet...
Normal function of the hypothalamic-pituitary growth axis in three dwarf Friesian foals.
The Veterinary record    September 29, 2009   Volume 165, Issue 13 373-376 doi: 10.1136/vr.165.13.373
de Graaf-Roelfsema E, Back W, Keizer HA, Stout TA, van der Kolk JH.Serial blood samples were collected from three dwarf Friesian foals to examine their endogenous growth hormone (GH) profiles, and the integrity of the GH-insulin-like growth factor-1 (IGF-1) axis was tested in one of them by examining its responses to the administration of GH-releasing hormone (GHRH) and to 10 days of treatment with recombinant equine GH. The basal serum concentrations of IGF-1 in the three dwarf foals were compared with those in nine age-matched normal foals. All the dwarf foals secreted endogenous GH. Stimulation with 7.0 microg/kg GHRH led to a 1400 per cent increase in pla...
Challenging the current paradigm of equine castration.
Veterinary surgery : VS    September 29, 2009   Volume 38, Issue 7 902-903 doi: 10.1111/j.1532-950X.2009.00591.x
Maxwell JA.No abstract available
Inguinal herniation of the large colon in a cob gelding four weeks after castration.
The Veterinary record    September 29, 2009   Volume 165, Issue 13 380-381 doi: 10.1136/vr.165.13.380
Ivens PA, Piercy RJ, Eliashar E.No abstract available
Endoscope-guided balloon sinuplasty of the equine nasomaxillary opening.
Veterinary surgery : VS    September 29, 2009   Volume 38, Issue 7 791-797 doi: 10.1111/j.1532-950X.2009.00579.x
Bell C, Tatarniuk D, Carmalt J.To describe and evaluate an endoscope-guided balloon sinuplasty technique for dilation of the equine nasomaxillary opening (NMO). Methods: Experimental study. Methods: Equine cadaver heads (n=5); Quarter Horses (n=4). Methods: A custom rigid balloon introducer was passed into position within the NMO at the caudal recess of the middle meatus. Under endoscopic guidance, a balloon catheter was passed via the introducer into the NMO and inflated to 6 atmospheres, for 30 seconds 3 times, to dilate the NMO. Drainage rates after sinuplasty were evaluated for the caudal maxillary sinus in 5 cadaver he...
Arthrodesis of the equine proximal interphalangeal joint: a biomechanical comparison of two parallel headless, tapered, variable-pitched, titanium compression screws and two parallel 5.5 mm stainless-steel cortical screws.
Veterinary surgery : VS    September 29, 2009   Volume 38, Issue 7 861-867 doi: 10.1111/j.1532-950X.2009.00574.x
Wolker RR, Carmalt JL, Wilson DG.To compare the biomechanical characteristics, failure mode, and effects of side (left or right limb) and end (forelimb or hindlimb) of different screws in 2-screw, parallel-screw proximal interphalangeal joint arthrodesis constructs in horses. Methods: In vitro experimental study. Methods: Twenty limbs from 6 cadavers (4 complete limb sets, 2 partial sets-total of 4 forelimb and 6 hindlimb pairs). Methods: Two parallel 5.5 mm cortical (AO) screws were inserted in lag fashion in 1 randomly allocated limb of a pair, and 2 parallel headless, tapered, variable-pitched, titanium compression screws ...
Two cases of equine pregnancy loss associated with Leptospira infection in England.
The Veterinary record    September 29, 2009   Volume 165, Issue 13 377-378 doi: 10.1136/vr.165.13.377
Whitwell KE, Blunden AS, Miller J, Errington J.No abstract available
Equine transcriptome quantification using human GeneChip arrays can be improved using genomic DNA hybridisation and probe selection.
Veterinary journal (London, England : 1997)    September 27, 2009   Volume 186, Issue 3 323-327 doi: 10.1016/j.tvjl.2009.08.030
Graham NS, Clutterbuck AL, James N, Lea RG, Mobasheri A, Broadley MR, May ST.Affymetrix GeneChip arrays are a powerful tool for transcriptome profiling and have been applied to a wide range of species. A genomic DNA (gDNA)-based probe selection method has been developed which broadens the range of species to which GeneChips may be successfully applied. This study demonstrated that gDNA-based probe selection on the Affymetrix U133+2 GeneChip array can be used to study the equine transcriptome which, to date, has received only limited attention. More than 29,000 transcripts can be detected in equine brain and liver and in primary cultures of equine articular chondrocytes...
Identification of 21 781 equine microsatellites on the horse genome assembly 2.0.
Animal genetics    September 26, 2009   Volume 41, Issue 2 222 doi: 10.1111/j.1365-2052.2009.01970.x
Mittmann EH, Wrede J, Pook J, Distl O.No abstract available
Moxidectin: a review of chemistry, pharmacokinetics and use in horses.
Parasites & vectors    September 25, 2009   Volume 2 Suppl 2, Issue Suppl 2 S5 doi: 10.1186/1756-3305-2-S2-S5
Cobb R, Boeckh A.This article reviews the current knowledge of the use of moxidectin (MOX) in horses, including its mode of action, pharmacokinetic and pharmacodynamic properties, efficacy, safety and resistance profile.Moxidectin is a second generation macrocyclic lactone (ML) with potent endectocide activity. It is used for parasite control in horses in an oral gel formulation. The principal mode of action of MOX and of other MLs is binding to gamma-aminobutyric (GABA) and glutamate-gated chloride channels. Moxidectin is different from other MLs in that it is a poor substrate for P-glycoproteins (P-gps) and ...
Effect of dietary omega-3 fatty acid source on plasma and red blood cell membrane composition and immune function in yearling horses.
Journal of animal science    September 25, 2009   Volume 88, Issue 1 248-257 doi: 10.2527/jas.2009-2253
Vineyard KR, Warren LK, Kivipelto J.To determine the effect of different sources of dietary n-3 fatty acids (FA) on plasma and red blood cell (RBC) FA composition and immune response, 18 Quarter Horse yearlings were randomly and equally assigned to 1 of 3 treatments: encapsulated fish oil (n = 6), milled flaxseed (n = 6), or no supplementation (control, n = 6). Fish oil contained 15 g of eicosapentaenoic acid (C20:5n-3) and 12.5 g of docosahexaenoic acid (C22:6n-3), and flaxseed contained 61 g of alpha-linolenic acid (C18:3n-3) per 100 g of FA. Horses had free access to bahiagrass pasture during the active growing season and wer...
Equine parasites: diagnosis and control – a current perspective.
Parasites & vectors    September 25, 2009   Volume 2 Suppl 2, Issue Suppl 2 I1 doi: 10.1186/1756-3305-2-S2-I1
Traversa D.No abstract available
Effects of worm control practices examined by a combined faecal egg count and questionnaire survey on horse farms in Germany, Italy and the UK.
Parasites & vectors    September 25, 2009   Volume 2 Suppl 2, Issue Suppl 2 S3 doi: 10.1186/1756-3305-2-S2-S3
von Samson-Himmelstjerna G, Traversa D, Demeler J, Rohn K, Milillo P, Schurmann S, Lia R, Perrucci S, di Regalbono AF, Beraldo P, Barnes H, Cobb R....For the control of worm infections, the strategic use of anthelmintics, often accompanied by additional farm and/or pasture management procedures, is currently applied on most horse farms in industrialized countries. However, the particular effects of the specific worm control procedures are often unclear and have only been investigated to a limited extent. We examined faecal egg count (FEC), faecal egg count reduction (FECR) and questionnaire data on farm and pasture management procedures. The aim of this study was to determine whether specific worm control practices reported to be applied in...
Determination of genomic DNA sequences for beta-tubulin isotype 1 from multiple species of cyathostomin and detection of resistance alleles in third-stage larvae from horses with naturally acquired infections.
Parasites & vectors    September 25, 2009   Volume 2 Suppl 2, Issue Suppl 2 S6 doi: 10.1186/1756-3305-2-S2-S6
Lake SL, Matthews JB, Kaplan RM, Hodgkinson JE.Genetic resistance against benzimidazole (BZ) anthelmintics is widespread in cyathostomins, the commonest group of intestinal parasitic nematodes of horses. Studies of BZ-resistant nematodes of sheep, particularly Haemonchus contortus, have indicated that an anthelmintic resistance-conferring T/A polymorphism, encoding an F (phenylalanine) to Y (tyrosine) substitution, in beta-tubulin isotype 1 is present at two loci, codons 167 and 200 (F167Y, F200Y). Recent studies using complementary (c) DNA derived from BZ-susceptible and -resistant cyathostomins identified statistical differences in the f...
Faecal Cyathostomin Egg Count distribution and efficacy of anthelmintics against cyathostomins in Italy: a matter of geography?
Parasites & vectors    September 25, 2009   Volume 2 Suppl 2, Issue Suppl 2 S4 doi: 10.1186/1756-3305-2-S2-S4
Milillo P, Boeckh A, Cobb R, Otranto D, Lia RP, Perrucci S, di Regalbono AF, Beraldo P, von Samson-Himmelstjerna G, Demeler J, Bartolini R, Traversa D.In the framework of a trial carried out in 2008 in Europe to evaluate the efficacy of major parasiticides against horse cyathostomins, pre- and/or post-treatment Faecal Egg Counts (FEC) were evaluated in a total of 84 yards and 2105 horses from nine different regions from the South, the Center, the North-Center and North-East of Italy. Specifically, on the basis of FECs of the horses present in each property, 60 out of the 84 yards were enrolled for a Faecal Egg Count Reduction Test (FECRT) using fenbendazole, pyrantel, ivermectin and moxidectin. Results: Of the 1646 horses bred in the 60 recr...
MMP-mediated collagen breakdown induced by activated protein C in equine cartilage is reduced by corticosteroids.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society    September 25, 2009   Volume 28, Issue 3 370-378 doi: 10.1002/jor.21001
Garvican ER, Vaughan-Thomas A, Redmond C, Gabriel N, Clegg PD.The plasma serine protease activated protein C (APC) is synthesized by human chondrocytes at sites of pathological cartilage fibrillation. APC levels are increased in osteoarthritis (OA) synovial fluid, and in vitro APC has been shown to synergize with interleukin-1beta (IL-1) to promote degradation from ovine cartilage. A model of equine cartilage degradation was established and used to explore corticosteroid activities. Intraarticular corticosteroids are a commonly prescribed treatment for joint disease, however their role in disease modification remains unclear. APC synergized with IL-1 or ...
Restrictions of anthelmintic usage: perspectives and potential consequences.
Parasites & vectors    September 25, 2009   Volume 2 Suppl 2, Issue Suppl 2 S7 doi: 10.1186/1756-3305-2-S2-S7
Nielsen MK.Given the increasing levels of anthelmintic resistance in equine parasites, parasitologists now recommend traditional treatment approaches to be abandoned and replaced by more sustainable strategies. It is of crucial importance to facilitate veterinary involvement to ensure that treatment decisions are based on parasitic knowledge. Despite recommendations given for the past two decades, strategies based on the selective therapy principle have not yet been implemented on a larger scale in equine establishments. In contrast, treatment regimens appear to be derived from recommendations originally...
Equine cyathostomins: a review of biology, clinical significance and therapy.
Parasites & vectors    September 25, 2009   Volume 2 Suppl 2, Issue Suppl 2 S1 doi: 10.1186/1756-3305-2-S2-S1
Corning S.The small strongyles of horses, also known as cyathostomins, are considered the most prevalent and pathogenic parasites of horses today. The clinical syndrome of larval cyathostominosis which occurs as a result of mass emergence of inhibited stages has a high fatality rate despite the best standard of care given to affected horses. Management of the challenge level of cyathostomins to prevent the syndrome is preferable. Many different management programmes have been tried over the past two decades, with mixed success. Programmes have relied heavily on repeated use of anthelmintic treatments th...
Role of melastatin-related transient receptor potential channel TRPM1 in the retina: Clues from horses and mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience    September 25, 2009   Volume 29, Issue 38 11720-11722 doi: 10.1523/JNEUROSCI.3275-09.2009
Schmidt TM.No abstract available
Anthelmintic resistance in cyathostomin populations from horse yards in Italy, United Kingdom and Germany.
Parasites & vectors    September 25, 2009   Volume 2 Suppl 2, Issue Suppl 2 S2 doi: 10.1186/1756-3305-2-S2-S2
Traversa D, von Samson-Himmelstjerna G, Demeler J, Milillo P, Schürmann S, Barnes H, Otranto D, Perrucci S, di Regalbono AF, Beraldo P, Boeckh A....A large survey was carried out in 2008 in Europe to evaluate the efficacy of fenbendazole (FBZ), pyrantel (PYR), ivermectin (IVM) and moxidectin (MOX), i.e. the major anthelmintic molecules used in current practice against cyathostomins affecting horses. A total of 102 yards and 1704 horses was studied in three countries: 60 yards and 988 horses from Italy, 22 and 396 from the UK, 20 and 320 from Germany. The survey consisted of Faecal Egg Count Reduction Tests (FECRTs) with a faecal egg count reduction (FECR) categorization of (I) resistance present if FECR <90% and the lower 95% confidenc...
Autistic rider.
Caring : National Association for Home Care magazine    September 24, 2009   Volume 28, Issue 8 62 
Hammerschlag CA.No abstract available
Ticks on domestic animals in Pernambuco, Northeastern Brazil. Dantas-Torres F.The objective of this article was to discuss some aspects of ticks associated with domestic animals in the State of Pernambuco, northeastern Brazil, based on a literature review and present new data obtained from recent tick collections carried out in this northeastern Brazilian state. From August 2007 to June 2008, 1,405 ticks were collected and five species were identified: Amblyomma cajennense (Fabricius, 1787), Amblyomma ovale Koch, 1844, Dermacentor nitens Neumann, 1897, Rhipicephalus (Boophilus) microplus (Canestrini, 1887), and Rhipicephalus sanguineus (Latreille, 1806). Dogs from urban...
Insect bite hypersensitivity in the horse: comparison of IgE-binding proteins in salivary gland extracts from Simulium vittatum and Culicoides nubeculosus.
Veterinary immunology and immunopathology    September 24, 2009   Volume 132, Issue 1 62-67 doi: 10.1016/j.vetimm.2009.09.016
Hellberg W, Mellor PS, Torsteinsdóttir S, Marti E.Insect bite hypersensitivity (IBH) is an IgE-mediated allergic dermatitis of horses caused by bites of insects such as Culicoides or Simulium spp. The aim of the present study was to compare the IgE-binding pattern of sera of IBH-affected horses to Culicoides nubeculosus and Simulium vittatum salivary gland extracts (SGE). Individual IgE responses to proteins of S. vittatum and C. nubeculosus SGEs were evaluated in 15 IBH-affected and three healthy horses on immunoblots. Fourteen out of the 15 IBH-affected but none of the healthy horses showed individual IgE binding patterns to seven and six m...
Cloning of IgE-binding proteins from Simulium vittatum and their potential significance as allergens for equine insect bite hypersensitivity.
Veterinary immunology and immunopathology    September 23, 2009   Volume 132, Issue 1 68-77 doi: 10.1016/j.vetimm.2009.09.017
Schaffartzik A, Weichel M, Crameri R, Björnsdóttir TS, Prisi C, Rhyner C, Torsteinsdóttir S, Marti E.Insect bite hypersensitivity (IBH) is an allergic dermatitis of horses caused by bites of Culicoides and sometimes Simulium spp. The aim of this investigation was to identify Simulium allergens associated with IBH. A phage surface display cDNA library expressing recombinant Simulium vittatum salivary gland proteins was screened using sera of IBH-affected horses sensitized to S. vittatum salivary gland proteins as shown in immunoblot, resulting in the identification of seven cDNAs encoding IgE-binding proteins. The deduced amino acid sequences of these proteins showed sequence similarities to a...
IgE in horses: occurrence in health and disease.
Veterinary immunology and immunopathology    September 23, 2009   Volume 132, Issue 1 21-30 doi: 10.1016/j.vetimm.2009.09.011
Wagner B.Since the initial characterization of IgE by Ishizaka et al. (1966), IgE was described in several mammalian species. In horses, a single gene encoding the IgE heavy chain constant region (IGHE gene) exists per haploid genome and several allelic variants of the equine IGHE gene were found. IgE occurs in its soluble form in equine serum and physiological concentrations of total IgE are around 1000-fold higher in normal horse than in normal human serum. Maternal IgE is enriched in the colostrum and transferred to the neonatal foal after birth. Foals do not produce detectable concentrations of end...
The effect of hormone treatments (hCG and cloprostenol) and season on the incidence of hemorrhagic anovulatory follicles in the mare: a field study.
Theriogenology    September 23, 2009   Volume 72, Issue 9 1262-1267 doi: 10.1016/j.theriogenology.2009.07.022
Cuervo-Arango J, Newcombe JR.The association between use of hormone treatments to induce estrus and ovulation and the incidence of hemorrhagic anovulatory follicles (HAFs) was studied in a mixed population of mares (Equus caballus) during two breeding seasons in a commercial breeding clinic. Mares treated with cloprostenol (CLO) were more likely to develop HAFs than were mares with spontaneous cycles (P0.05) from that of mares with ovulatory cycles (10.5+/-1.5 yr).
Potential treatments for insulin resistance in the horse: a comparative multi-species review.
Veterinary journal (London, England : 1997)    September 23, 2009   Volume 186, Issue 3 282-291 doi: 10.1016/j.tvjl.2009.08.032
Tinworth KD, Harris PA, Sillence MN, Noble GK.Insulin resistance and hyperinsulinaemia increase the risk of laminitis and horse owners and veterinarians should attempt to enhance insulin sensitivity in at-risk groups. In obese animals this may be achieved, in part, by promoting weight loss and increasing exercise, but such intervention may not be appropriate in non-obese insulin-resistant animals, or where exercise is contra-indicated for clinical reasons. An alternative approach to controlling insulin sensitivity in obese and non-obese horses may be the use of certain herbal compounds that have shown promise in humans and laboratory anim...
[Construction and in vitro evaluation of an infectious clone of the equine infectious anemia virus vaccine strain EIAV(FDDV) with four reverse-mutated vaccine-specific sites in the S2 gene].
Bing du xue bao = Chinese journal of virology    September 23, 2009   Volume 25, Issue 4 309-315 
Gao X, Jiang CG, Han XE, Zhao LP, Shen RX, Xiang WH, Zhou JH.To elucidate the function of the S2 gene in equine infectious anemia virus (EIAV) and its role in the attenuation of the Chinese attenuated EIAV vaccine strains, the S2 in the EIAV vaccine strain EIAV (FDDV) was reverse-mutated and the in vitro replication character of the resultant virus was evaluated. Based on the sequence variation of the S2 gene between the EIAV virulent strains and vaccine strains, all the four vaccine-specific sites in the S2 of an EIAV(FDDV) infectious clone, pFDDV3-8, were reverse-mutated to the sequences of the virulent strain EIAV(DV115). The reverse-mutated molecula...
Pedigree analysis in the Austrian Noriker draught horse: genetic diversity and the impact of breeding for coat colour on population structure.
Journal of animal breeding and genetics = Zeitschrift fur Tierzuchtung und Zuchtungsbiologie    September 22, 2009   Volume 126, Issue 5 348-356 doi: 10.1111/j.1439-0388.2008.00790.x
Druml T, Baumung R, Sölkner J.The pedigree of the current Austrian Noriker draught horse population comprising 2808 horses was traced back to the animals considered as founders of this breed. In total, the number of founders was 1991, the maximum pedigree length was 31 generations, with an average of 12.3 complete generations. Population structure in this autochthonous Austrian draught horse breed is defined by seven breeding regions (Carinthia, Lower Austria, Salzburg, Styria, Tyrol, Upper Austria and Vorarlberg) or through six coat colour groups (Bay, Black, Chestnut, Roan, Leopard, Tobiano). Average inbreeding coefficie...