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Topic:Equine Medicine

Equine Medicine encompasses the study and application of medical practices specifically related to the health and well-being of horses. This field involves the diagnosis, treatment, and prevention of diseases and disorders affecting equine species. It covers a wide range of topics, including internal medicine, surgery, reproduction, and pharmacology. Research in equine medicine often focuses on understanding the physiological and pathological processes unique to horses, as well as developing effective therapeutic interventions. This page aggregates peer-reviewed research studies and scholarly articles that explore various aspects of equine medicine, providing insights into the latest advancements and methodologies in the care and management of horse health.
Prognostic value of colonic and peripheral venous lactate measurements in horses with large colon volvulus.
Veterinary surgery : VS    January 9, 2020   Volume 49, Issue 3 472-479 doi: 10.1111/vsu.13361
Orr KE, Baker WT, Lynch TM, Hughes FE, Clark CK, Slone DE, Fogle CA, Gonzalez LM.To determine the prognostic value of (1) colonic venous lactate or peripheral lactate values obtained before and after manual correction of a large colon volvulus and (2) a combination of variables including pelvic flexure biopsy. Methods: Prospective clinical study. Methods: Forty adult horses in which large colon volvulus was diagnosed intraoperatively. Methods: Colonic venous, peripheral venous, and arterial blood samples were collected to measure lactate values before and after manual correction. Mucosal biopsy samples were obtained in cases that underwent enterotomy or colonic resection a...
[Colonel Hermann Schwyter, equine surgeon, a formative personality of equine medicine].
Schweizer Archiv fur Tierheilkunde    January 4, 2020   Volume 162, Issue 1 53-60 doi: 10.17236/sat00243
Meier H.The biography of Colonel Hermann Schwyter, equine surgeon of the Swiss Army from 1928 to 1937, and the history of training of farriers in Switzerland since the 18th century are presented. Hermann Schwyters dissertation examined the changes of equine hoof confirmation as a result of standing and gait in approximately 2,000 horses and numerous anatomical specimens. He defines the foot placement, describes possible variations, their causes and effects. Significant is also his study of the compression pathology in horses and mules. His recommendations are still valid today. The present article ref...
Morphological and Imaging Evaluation of the Metacarpophalangeal and Metatarsophalangeal Joints in Healthy and Lame Donkeys.
Journal of equine veterinary science    December 26, 2019   Volume 88 102904 doi: 10.1016/j.jevs.2019.102904
El-Gendy SAA, Alsafy MAM, Rutland CS, El-Khamary AN, Abu-Ahmed HM, El-Kammar MH.The donkey is of socio-economic value yet imaging techniques in both healthy and abnormal limbs are a limiting factor in research and medicine. The objective was to determine anatomical features of both healthy and clinically abnormal donkey metacarpophalangeal and metatarsophalangeal joints (n = 13) using anatomical dissection, casting, X-ray and computed tomography. The joint capsule contained two palmar/plantar and two dorsal recesses. The proximal-palmar or plantar recess was larger than the distodorsal recess and potential sites of approaches to the recesses were determined. Soft tissue ...
Can Extracorporeal Shockwave Promote Osteogenesis of Equine Bone Marrow-Derived Mesenchymal Stem Cells In Vitro?
Stem cells and development    December 17, 2019   Volume 29, Issue 2 110-118 doi: 10.1089/scd.2019.0202
Colbath AC, Kisiday JD, Phillips JN, Goodrich LR.Both bone marrow-derived mesenchymal stem cells (BMDMSCs) and extracorporeal shockwave (ESW) have shown promise for enhancing fracture repair. If exposure of BMDMSCs to ESW enhances osteogenic differentiation, these therapies may be combined in vivo or used as a method for preconditioning BMDMSCs. The objective of this study was to determine the effect of ESW on the osteogenic ability of equine BMDMSCs. We hypothesized that ESW would promote osteogenesis evidenced by increased gene expression, alkaline phosphatase (ALPL) expression, slide morphologic score, and protein expression. BMDMSCs were...
Time of first polar body extrusion affects the developmental competence of equine oocytes after intracytoplasmic sperm injection.
Reproduction, fertility, and development    November 21, 2019   Volume 31, Issue 12 1805-1811 doi: 10.1071/RD19248
Rodríguez MB, Gambini A, Clérico G, Ynsaurralde-Rivolta AE, Briski O, Largel H, Sansinena M, Salamone DF.Assisted reproduction techniques (ARTs) have become widespread in the equine breeding industry. In particular, the combination of oocyte recovery from live mares followed by IVM and intracytoplasmic sperm injection (ICSI) has increased markedly among the ARTs used with valuable or low-fertility animals. There is currently no consensus among research groups regarding the optimal oocyte maturation period to produce high-quality embryos. In this study, we report the maturation dynamics of equine oocytes at different time points, from 20 to 40h (Experiment 1). In addition, in Experiment 2, equine ...
What is your diagnosis? Nasal lesion in a horse with exophthalmos.
Veterinary clinical pathology    November 7, 2019   Volume 48, Issue 4 771-773 doi: 10.1111/vcp.12790
Zibura AE, Manning LK, Gwynn A, Sharkey L, de Linde Henriksen M, Coppelman E, O'Brien TD.No abstract available
Piroplasmosis in Italian Standardbred Horses: 15 Years of Surveillance Data.
Journal of equine veterinary science    October 18, 2019   Volume 83 102813 doi: 10.1016/j.jevs.2019.102813
Padalino B, Rosanowski SM, Di Bella C, Lacinio R, Rubino GTR.This study aimed to document the prevalence of chronic equine piroplasmosis (EP) in poorly performing Standardbred racehorses and to explore associations between the disease and sex, age, and hematological parameters. Blood was collected between 2004 and 2018; blood cell counts were performed using a cell counter analyzer, biochemical parameters using a photometer, and serum proteins using agarose gel electrophoresis. Blood smears were prepared, colored with a modified Giemsa, and an experienced technician identified the presence of protozoa. The horses were categorized into piroplasmosis posi...
Phaeohyphomycotic Rhinitis Caused by Bipolaris hawaiiensis in a Horse.
Journal of equine veterinary science    October 1, 2019   Volume 82 102798 doi: 10.1016/j.jevs.2019.102798
Legere RM, Wooldridge AA, Sandey M, Hanson RR, Cole R.This case represents the first reported case of Bipolaris hawaiiensis infection in an equid, and its aggressive clinical course. This case provides important descriptive and prognostic information for horses diagnosed with phaeohyphomycotic rhinitis. A 19-year-old American Quarter Horse mare was presented for second opinion of stertor and exercise intolerance of four-month duration. Endoscopy revealed generalized, proximal nasal edema, and computed tomography identified a soft tissue mass eroded through the rostral nasal bone. Biopsy of the mass was identified as a fungal granuloma caused by B...
Delayed onset vagus nerve paralysis after occipital condyle fracture in a horse.
Journal of veterinary internal medicine    September 26, 2019   Volume 33, Issue 6 2780-2785 doi: 10.1111/jvim.15581
Martin-Giménez T, Cruz AM, Barragán A, Montero E, Sanchez PG, Caballero G, Corradini I.Occipital condylar fractures (OCFs) causing delayed onset lower cranial nerve paralysis (LCNPs) are rare. We present a 7-year-old Friesian horse with delayed onset dysphagia caused by vagus nerve (CNX) paralysis and suspicion of glossopharyngeal nerve (CNIX) paralysis developed several days after a minor head injury. Endoscopic examination revealed right laryngeal hemiplegia and intermittent dorsal displacement of the soft palate. An area of submucosal hemorrhage and bulging was appreciated over the dorsal aspect of the medial compartment of the right guttural pouch. Radiological examination o...
Diffusion of fluoroquinolones into equine fetal fluids did not induce fetal lesions after enrofloxacin treatment in early gestation.
Veterinary journal (London, England : 1997)    September 7, 2019   Volume 253 105376 doi: 10.1016/j.tvjl.2019.105376
Ellerbrock RE, Canisso IF, Podico G, Roady PJ, Uhl E, Lima FS, Li Z.While recent work demonstrated that enrofloxacin and ciprofloxacin reach the fetoplacental unit without causing obvious lesions in the 9-month-old equine fetus or resulting foal, many practitioners still hesitate to prescribe a fluoroquinolone during pregnancy. Since early gestation is a critical time for fetal skeletal development, if fluoroquinolones are chondrotoxic to the fetus at any point during gestation, this period would be important. The aim of this study was to assess the effects of 2 weeks' exposure to enrofloxacin on the equine fetus between 46 and 60 days gestation. Twelve pregna...
Dear Donkey and Mule: You Deserve More Appreciation and Better Medicine.
The Veterinary clinics of North America. Equine practice    September 3, 2019   Volume 35, Issue 3 xiii-xiv doi: 10.1016/j.cveq.2019.08.015
Toribio RE.No abstract available
State-of-the-Art Diagnostic Methods to Diagnose Equine Spinal Disorders, With Special Reference to Transcranial Magnetic Stimulation and Transcranial Electrical Stimulation.
Journal of equine veterinary science    September 3, 2019   Volume 81 102790 doi: 10.1016/j.jevs.2019.102790
Journée SL, de Meeus d'Argenteuil C, De Maré L, Boshuizen B, Vanderperren K, Journée LH, de Bruijn M, Bergmann W, Delesalle C.Spinal cord disorders are a common problem in equine medicine. However, finding the site of the lesion is challenging for veterinarians because of a lack of sensitive diagnostic methods that can assess neuronal functional integrity in horses. Although medical imaging is frequently applied to help diagnose corticospinal disorders, this approach does not reveal functional information. For the latter, transcranial magnetic stimulation (TMS) and more recently transcranial electrical stimulation (TES) can be useful. These are brain stimulation techniques that create either magnetic or electrical fi...
Equine cheek tooth extraction: Comparison of outcomes for five extraction methods.
Equine veterinary journal    July 30, 2019   Volume 52, Issue 2 181-186 doi: 10.1111/evj.13150
Caramello V, Zarucco L, Foster D, Boston R, Stefanovski D, Orsini JA.Post-operative complications are reported for all methods of equine cheek tooth extraction but not all methods carry the same risks. An outcome comparison for commonly used methods is needed so that clinicians can make informed treatment decisions. Objective: We conducted a side-by-side comparison of five cheek tooth extraction methods, comparing types and incidence of complications among oral extraction, tooth repulsion (three surgical approaches) and lateral buccotomy techniques. Methods: Retrospective clinical study using hospital medical records. Methods: Medical records of all horses unde...
Sex identification in horses (Equus caballus) based on the gene pair NLGN4X/NLGN4Y.
Animal genetics    July 10, 2019   Volume 50, Issue 5 551 doi: 10.1111/age.12823
Zaffalon S, Latz A, Krasteva-Christ G, Maxeiner S.No abstract available
And Now for Something Completely Different: Some Controversies in Equine Medicine, Surgery, and Reproduction.
The Veterinary clinics of North America. Equine practice    July 8, 2019   Volume 35, Issue 2 xi-xii doi: 10.1016/j.cveq.2019.05.001
MacKay RJ.No abstract available
Girthiness: Retrospective Study of 37 Horses (2004-2016).
Journal of equine veterinary science    June 8, 2019   Volume 79 100-104 doi: 10.1016/j.jevs.2019.05.025
Millares-Ramirez EM, Le Jeune SS.Girth aversion or girthiness is a nonspecific clinical sign anecdotally associated with multiple conditions in the horse (behavioral problems, gastric ulcers, back pain); however, studies have not been conducted to definitively correlate this clinical sign to specific pathologies. This retrospective study aims to describe the clinical signs and final diagnoses of 37 horses evaluated at the University of California, Davis with a presenting complaint of girthiness. Medical records of all horses presented to the veterinary hospital between 2004 and 2016 for girthiness were reviewed. Twelve horses...
Analysis of neurofilament concentration in healthy adult horses and utility in the diagnosis of equine protozoal myeloencephalitis and equine motor neuron disease.
Research in veterinary science    May 11, 2019   Volume 125 1-6 doi: 10.1016/j.rvsc.2019.04.018
Morales Gómez AM, Zhu S, Palmer S, Olsen E, Ness SL, Divers TJ, Bischoff K, Mohammed HO.Neurofilaments (NFs) are structural proteins of neurons that are released in significant quantities in the cerebrospinal fluid and blood as a result of neuronal degeneration or axonal damage. Therefore, NFs have potential as biomarkers for neurologic disorders. Neural degeneration increases with age and has the potential to confound the utility of NFs as biomarkers in the diagnosis of neurologic disorders. We investigated this relationship in horses with and without neurological diagnosis. While controlling for horse type (draft, pleasure, and racing), we evaluated the relationship between ser...
A Suspected Case of Rocky Mountain Spotted Fever in an Adult Horse in the Southeastern United States.
Journal of equine veterinary science    May 11, 2019   Volume 78 134-137 doi: 10.1016/j.jevs.2019.05.003
Freese S, Sheats MK.A 20-year-old Paint gelding was evaluated for fever of unknown origin. History and clinical signs were consistent with potential tick-borne disease. Samples were collected and submitted for tick-borne disease panel, herpes virus, complete blood count, and serum biochemistry. Based on physical examination findings and vaccination history, the gelding was treated for suspected tick-borne disease with oxytetracycline (8 mg/kg intravenously BID) for 5 days, followed by doxycycline (10 mg/kg PO BID) for an additional 5 days. Although titers to Borrelia burgdorferi, Anaplasma phagocytophilum, an...
First description of Theiler’s disease-associated virus infection and epidemiological investigation of equine pegivirus and equine hepacivirus coinfection in Brazil.
Transboundary and emerging diseases    May 8, 2019   Volume 66, Issue 4 1737-1751 doi: 10.1111/tbed.13210
Figueiredo AS, de Moraes MVDS, Soares CC, Chalhoub FLL, de Filippis AMB, Dos Santos DRL, de Almeida FQ, Godoi TLOS, de Souza AM, Burdman TR....Recent advances in the study of equine pegivirus (EPgV), Theiler's disease-associated virus (TDAV) and equine hepacivirus (EqHV) highlight their importance to veterinary and human health. To gain some insight into virus distribution, possible risk factors, presence of liver damage and genetic variability of these viruses in Brazil, we performed a cross-sectional study of EPgV and TDAV infections using a simultaneous detection assay, and assessed EqHV coinfection in different horse cohorts. Of the 500 serum samples screened, TDAV, EPgV and EPgV-EqHV were present in 1.6%, 14.2% and 18.3%, respec...
Potential new sources of hypoglycin A poisoning for equids kept at pasture in spring: a field pilot study.
The Veterinary record    May 2, 2019   Volume 184, Issue 24 740 doi: 10.1136/vr.104424
Votion DM, Habyarimana JA, Scippo ML, Richard EA, Marcillaud-Pitel C, Erpicum M, Gustin P.Equine atypical myopathy in Europe results from hypoglycin A (HGA) exposure through the ingestion of samaras or seedlings of the sycamore maple tree. This pilot study aimed at better defining sources of HGA intoxication in spring. Samaras fallen on the ground and then seedlings were collected at two-week intervals from sycamore, Norway, and field maple trees over the spring 2016. In early April, rainwater from wet seedlings collected after a rainy night was harvested to be analysed. Mid-May, samaras of the box elder, common ash, and inflorescences of sycamore maples were collected on the tree....
Haematological profile in foals during the first year of life.
The Veterinary record    April 17, 2019   Volume 184, Issue 16 503 doi: 10.1136/vr.104461
Faramarzi B, Rich L.Foals' haematological values change constantly during their first year of life. The use of updated age-based reference intervals (RIs) is imperative for providing accurate diagnosis and optimum care for sick foals. The authors' objective was to provide updated RIs for 13 haematological values in 2, 7, 14, 30, 90, 180 and 365-day-old foals and to investigate the changes over time in each measured value. Venous blood was collected at those ages from clinically healthy foals. Thirteen haematological values were analysed. The 95% RIs were reported using a bootstrapping method. Differences over tim...
Clinical insights: Equine dentistry.
Equine veterinary journal    April 6, 2019   Volume 51, Issue 3 277-279 doi: 10.1111/evj.13083
Barnett TP.No abstract available
Oral Administration of Meloxicam Suppresses Low-Dose Endotoxin Challenge-Induced Pain in Thoroughbred Horses.
Journal of equine veterinary science    March 21, 2019   Volume 77 139-143 doi: 10.1016/j.jevs.2019.03.001
Urayama S, Tanaka A, Kusano K, Sato H, Nagashima T, Fukuda I, Fujisawa C, Matsuda H.Nonsteroidal anti-inflammatory drugs such as flunixin meglumine have been used to treat signs of systemic inflammatory conditions, but it is also known to have the side effect to small intestine mucosa. It may be considered to be due to inhibition of both cyclooxygenase (COX)-1 and COX-2. On the other hand, meloxicam is widely used in equine clinical practice and an effective nonsteroidal anti-inflammatory drug with the preferential inhibitory effect on COX-2. However, it has not yet been evaluated in equine systemic inflammation. The aim of this study was to evaluate the effect of meloxicam a...
Middle East respiratory syndrome coronavirus infection in non-camelid domestic mammals.
Emerging microbes & infections    March 15, 2019   Volume 8, Issue 1 103-108 doi: 10.1080/22221751.2018.1560235
Kandeil A, Gomaa M, Shehata M, El-Taweel A, Kayed AE, Abiadh A, Jrijer J, Moatasim Y, Kutkat O, Bagato O, Mahmoud S, Mostafa A, El-Shesheny R....Dromedary camels are natural host of the Middle East respiratory syndrome coronavirus (MERS-CoV). However, there are limited studies of MERS-CoV infection of other domestic mammals exposed to infected dromedaries. We expanded our surveillance among camels in Egypt, Tunisia, and Senegal to include other domestic mammalian species in contact with infected camels. A total of 820 sera and 823 nasal swabs from cattle, sheep, goats, donkeys, buffaloes, mules, and horses were collected. Swabs were tested using RT-PCR and virus RNA-positive samples were genetically sequenced and phylogenetically analy...
In vitro antimicrobial susceptibility of equine clinical isolates from France, 2006-2016.
Journal of global antimicrobial resistance    March 15, 2019   Volume 19 144-153 doi: 10.1016/j.jgar.2019.03.006
Duchesne R, Castagnet S, Maillard K, Petry S, Cattoir V, Giard JC, Leon A.This study aimed to analyse antimicrobial susceptibility evolution of equine pathogens isolated from clinical samples from 2006-2016. A collection of 25 813 bacterial isolates was studied, clustered according to their origins (respiratory tract, cutaneous, genital and other), and analysed for their antimicrobial susceptibility using the disk diffusion method. The most frequently isolated pathogens were group C Streptococci (27.6%), Escherichia coli (20.0%), Staphylococcus aureus (7.8%), Pseudomonas aeruginosa (4.0%), Enterobacter spp. (3.4%), Klebsiella pneumoniae (2.4%), and Rhodococcus equi ...
Peripheral blood-derived mesenchymal stem cells demonstrate immunomodulatory potential for therapeutic use in horses.
PloS one    March 14, 2019   Volume 14, Issue 3 e0212642 doi: 10.1371/journal.pone.0212642
Longhini ALF, Salazar TE, Vieira C, Trinh T, Duan Y, Pay LM, Li Calzi S, Losh M, Johnston NA, Xie H, Kim M, Hunt RJ, Yoder MC, Santoro D, McCarrel TM....Previously, we showed that mesenchymal stem cells (MSC) can be mobilized into peripheral blood using electroacupuncture (EA) at acupoints, LI-4, LI-11, GV-14, and GV-20. The purpose of this study was to determine whether EA-mobilized MSC could be harvested and expanded in vitro to be used as an autologous cell therapy in horses. Peripheral blood mononuclear cells (PBMC) isolated from young and aged lame horses (n = 29) showed a marked enrichment for MSCs. MSC were expanded in vitro (n = 25) and administered intravenously at a dose of 50 x 106 (n = 24). Treatment resulted in significant improve...
A Comparative Review of Equine SIRS, Sepsis, and Neutrophils.
Frontiers in veterinary science    March 12, 2019   Volume 6 69 doi: 10.3389/fvets.2019.00069
Sheats MK.The most recent definition of sepsis in human medicine can be summarized as organ dysfunction caused by a dysregulated host response to infection. In equine medicine, although no consensus definition is available, sepsis is commonly described as a dysregulated host systemic inflammatory response to infection. Defense against host infection is the primary role of innate immune cells known as neutrophils. Neutrophils also contribute to host injury during sepsis, making them important potential targets for sepsis prevention, diagnosis, and treatment. This review will present both historical and u...
Problem of Pin Breakage in Equine Transfixation Pin Casting: Biomechanical Ex Vivo Testing of Four Different Pins.
Veterinary and comparative orthopaedics and traumatology : V.C.O.T    March 7, 2019   Volume 32, Issue 3 222-233 doi: 10.1055/s-0039-1678734
Keller SA, Valet S, Martens A, Weisse B, Fürst AE, Kümmerle JM. The aim of this study was to evaluate cyclic fatigue behaviour of a new pin with a thread run-out design in comparison with three other types of pins commonly used for equine transfixation pin casting. Methods:  Twenty-four pairs of equine cadaveric third metacarpal bones (MC3) equipped with one transfixation pin placed horizontally in the distal metaphysis were tested using a simplified model, mimicking the biomechanical situation of equine transfixation pin casting. A 6.3/8.0-mm Imex Duraface pin with thread run-out design (ITROP) was compared with a 6.1-mm smooth Steinmann pin (SSP), a...
An unusual case of giant cell tumor of soft parts in an American Warmblood horse.
Open veterinary journal    February 26, 2019   Volume 9, Issue 1 44-48 doi: 10.4314/ovj.v9i1.8
Zimmerman K, Almy F, Saunders G, Crisman M, Leonardi L.Fine needle aspiration and tissue biopsy samples were taken from a subcutaneous mass in the cranial stifle region of a 10-yr-old horse. Key cytologic features included numerous mildly to moderately pleomorphic histiocytic cells admixed with mononuclear inflammatory cells, occasional fibroblasts, multinucleated cells, and hemosiderin-laden macrophages. Based on these features, cytologic differentials included granulomatous inflammation with reactive fibroplasia, histiocytic sarcoma, giant cell tumor of soft parts (GCTSPs), and giant cell tumor of bone. The tissue biopsy supported a diagnosis of...
Fluoroscopically guided neocanalization for treatment of nasolacrimal atresia in two horses.
Veterinary ophthalmology    February 15, 2019   Volume 22, Issue 4 538-544 doi: 10.1111/vop.12653
Berkowski W, Plummer CE, Ramos R, Czerwinski S, Brooks D, Gallagher A.A yearling Thoroughbred stallion and an 8-year-old Saddlebred mare were evaluated for persistent mucoid ocular discharge. Results: Examination of both horses revealed copious yellow-tan mucoid ocular discharge with a negative Jones I test, absent nasal punctum, and unsuccessful anterograde nasolacrimal duct (NLD) irrigation. Clinical abnormalities were present on the right side only in one horse and bilaterally in the other. Computed tomography (CT) with contrast confirmed nasolacrimal duct atresia in both horses. Results: Under general anesthesia, the affected NLD was catheterized anterograde...
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