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Topic:Equine Medicine

Equine Medicine encompasses the study and application of medical practices specifically related to the health and well-being of horses. This field involves the diagnosis, treatment, and prevention of diseases and disorders affecting equine species. It covers a wide range of topics, including internal medicine, surgery, reproduction, and pharmacology. Research in equine medicine often focuses on understanding the physiological and pathological processes unique to horses, as well as developing effective therapeutic interventions. This page aggregates peer-reviewed research studies and scholarly articles that explore various aspects of equine medicine, providing insights into the latest advancements and methodologies in the care and management of horse health.
Pelger-Huët anomaly in an Arabian horse.
Veterinary clinical pathology    September 7, 2007   Volume 36, Issue 3 306-310 doi: 10.1111/j.1939-165x.2007.tb00231.x
Grondin TM, DeWitt SF, Keeton KS.A 9-year-old Arabian mare was evaluated for a 7-day history of malaise. Results of a CBC included a leukocyte concentration within the reference interval (8.4 x 10(3)/microL, reference interval 6.0-14.0 x 10(3)/microL) with an apparent degenerative left shift (segmented neutrophils 1.2 x 10(3)/microL, reference interval 2.5-7.5 x 10(3)/microL; hyposegmented neutrophils 1.8 x 10(3)/microL, reference interval 0.0-0.2 x 10(3)/microL). Serum clinical chemistry results included increased aspartate transaminase, alkaline phosphatase, and gamma-glutamyltransferase activities. A presumptive diagnosis ...
Gabapentin for the treatment of neuropathic pain in a pregnant horse.
Journal of the American Veterinary Medical Association    September 4, 2007   Volume 231, Issue 5 755-758 doi: 10.2460/javma.231.5.755
Davis JL, Posner LP, Elce Y.A 24-year-old 732-kg (1,610-lb) pregnant Belgian draft horse mare developed neuropathy and signs of intractable pain following colic surgery. Results: Following recovery from colic surgery to treat compression of the small and large intestines because of a large fetus, the mare was noticed to have signs of femoral neuropathy involving the left hind limb. Within 36 hours after recovery, the mare developed signs of severe pain that were unresponsive to conventional treatment. No gastrointestinal tract or muscular abnormalities were found, and the discomfort was attributed to neuropathic pain. Re...
[Organization Horse commences].
Tijdschrift voor diergeneeskunde    July 14, 2007   Volume 132, Issue 12 482-484 
de Groot SJ, Gostelie HR.No abstract available
Evidence-based medicine in equine critical care.
The Veterinary clinics of North America. Equine practice    July 10, 2007   Volume 23, Issue 2 293-316 doi: 10.1016/j.cveq.2007.04.001
Bedenice D.One of the fundamental skills required for practicing evidence-based medicine is the development of a well-built clinical question, which specifies the patient group or problem, intervention, and outcome of interest. For this purpose, various "levels of evidence" have been developed in the human literature, which rank the validity of evidence. Our established conclusions and advice are thus supported by specific "grades of recommendations," which are intended to give an indication of the "strength" of a clinical recommendation. This article was compiled with these principles in mind.
Common procedures in broodmare practice: what is the evidence?
The Veterinary clinics of North America. Equine practice    July 10, 2007   Volume 23, Issue 2 385-402 doi: 10.1016/j.cveq.2007.03.003
Brinsko SP.Many procedures performed as part of routine broodmare practice are based on sound clinical judgment and experience or scientific evidence; however, others are based on perceived problems and needs to address them. This article presents four procedures commonly used in broodmare practice, for which there is questionable evidence to substantiate their use.
Evidence-based respiratory medicine in horses.
The Veterinary clinics of North America. Equine practice    July 10, 2007   Volume 23, Issue 2 215-227 doi: 10.1016/j.cveq.2007.03.006
Williamson KK, Davis MS.It is clear from a review of the current scientific literature that an evidence-based approach to medical treatment of equine respiratory disease can be applied, at least in the instance of common lower respiratory diseases. In particular, there is clear evidence for efficacious treatments for recurrent airway obstruction and exercise-induced pulmonary hemorrhage, and with the recognition of this evidence, these treatments should be the first to be considered by a practitioner when treating these conditions. The purpose of this article is not only to identify the existence of relevant high-qua...
Establishment of a panel of reference Trypanosoma evansi and Trypanosoma equiperdum strains for drug screening.
Veterinary parasitology    July 10, 2007   Volume 148, Issue 2 114-121 doi: 10.1016/j.vetpar.2007.05.020
Gillingwater K, Büscher P, Brun R.The animal pathogenic protozoan, Trypanosoma evansi, leads to a wasting disease in equines, cattle and camels, commonly known as Surra. It is extensively distributed geographically with a wide range of mammalian hosts and causes great economical loss. Trypanosoma equiperdum causes a venereal disease called Dourine in horses and donkeys. Chemotherapy appears to be the most effective form of control for T. evansi, whereas infections caused by T. equiperdum are considered incurable. Due to emerging drug resistance, efficient control of T. evansi is severely threatened, emphasising the urgent need...
Cetirizine in horses: pharmacokinetics and pharmacodynamics following repeated oral administration.
Veterinary journal (London, England : 1997)    June 19, 2007   Volume 177, Issue 2 242-249 doi: 10.1016/j.tvjl.2007.03.026
Olsén L, Bondesson U, Broström H, Tjälve H, Ingvast-Larsson C.The pharmacokinetics of the histamine H(1)-antagonist cetirizine and its effect on histamine-induced cutaneous wheal formation were studied in six healthy horses following repeated oral administration. After three consecutive administrations of cetirizine (0.2 mg/kg body weight, bw) every 12h, the trough plasma concentration of cetirizine was 16+/-4 ng/mL (mean+/-SD) and the wheal formation was inhibited by 45+/-23%. After four additional administrations of cetirizine (0.4 mg/kg bw) every 12 h, the trough plasma concentration was 48+/-15 ng/mL and the wheal formation was inhibited by 68+/-11%....
The clinical evidence article by Proudman et al. (2007).
Equine veterinary journal    May 25, 2007   Volume 39, Issue 3 287 
Freeman DE.No abstract available
VetCell Bioscience Ltd–regenerative medicine for the world of animal health.
Regenerative medicine    May 1, 2007   Volume 1, Issue 3 393-396 doi: 10.2217/17460751.1.3.393
Mountford D.VetCell Bioscience is a UK-based company focused on pioneering the use of regenerative medicine in the animal health market. VetCell was formed in partnership with the Royal Veterinary College and the Institute for Orthopaedic and Musculoskeletal Science to develop the use of cellular therapies to treat athletic injuries in horses. This ground-breaking work has been the springboard from which the Company has expanded into other areas of veterinary regenerative medicine.
Head and body centre of mass movement in horses trotting on a circular path.
Equine veterinary journal. Supplement    April 4, 2007   Issue 36 462-467 doi: 10.1111/j.2042-3306.2006.tb05588.x
Clayton HM, Sha DH.Horses are often worked along a circular trajectory but the mechanics of turning have not been reported. Objective: To develop a methodology for kinematic analysis of horses during circling and to report preliminary findings describing movements of the total body centre of mass (COMbody). Methods: Seventy-five skin markers, distributed over the head, neck, trunk and limbs of 5 sound horses, were tracked in a global coordinate system at 120 Hz as the horses trotted around a small circle. Based on segmental inertial data, 3D positions of the segmental centres of mass and COMbody were calculated....
Measurements of right ventricular internal dimensions and their relationships to severity of tricuspid valve regurgitation in national hunt thoroughbreds.
Equine veterinary journal. Supplement    April 4, 2007   Issue 36 171-177 doi: 10.1111/j.2042-3306.2006.tb05535.x
Helwegen MM, Young LE, Rogers K, Wood JL.The effect of tricuspid valve regurgitation (TR) in right ventricular (RV) chamber size has not been reported. Methods: An echocardiographic and auscultation study was conducted on 394 race-fit National Hunt Thoroughbreds (TBs) in 4 training yards. Auscultation was performed on each horse and audible murmurs of TR graded using a 1-6 scale. Echocardiography was also performed and standard, 2-dimensional (2D), short (SA) and long axis (LA) images of the RV obtained from a right parasternal location. An m-mode image was recorded from an SA view of the RV just below the level of the tricuspid valv...
Fire and smoke inhalation injury in horses.
The Veterinary clinics of North America. Equine practice    March 24, 2007   Volume 23, Issue 1 19-30 doi: 10.1016/j.cveq.2006.11.005
Marsh PS.Although not common in horses, fire and smoke inhalation trauma may require veterinary assistance at several levels. Most commonly, the equine clinician is called on to provide care of potentially complex and emotionally charged cases. Thermal injury, along with smoke inhalation, can cause local and diffuse lesions. Massive tissue edema may occur, which can be a challenge to manage as well as creating organ dysfunction at distant sites. Further complications of severely affected patients are varied and include life-threatening sepsis. This article reviews some of the important features of this...
Oxidative stress.
The Veterinary clinics of North America. Equine practice    March 24, 2007   Volume 23, Issue 1 135-157 doi: 10.1016/j.cveq.2006.11.004
Soffler C.Oxidative stress refers to the cellular injury and pathologic change that occurs when there is an imbalance favoring oxidants over antioxidants within a living organism. In human medicine, oxidative stress has been implicated in numerous disease processes, which has led to further research into the clinical benefits and efficacy of antioxidant therapy. The evaluation of oxidative stress in the horse has been limited primarily to ischemia-reperfusion injury of the gastrointestinal tract, recurrent airway obstruction, exercise, osteoarthritis, equine motor neuron disease, and pituitary pars inte...
Comparison of prednisolone and dexamethasone effects in the presence of environmental control in heaves-affected horses.
Veterinary journal (London, England : 1997)    March 23, 2007   Volume 175, Issue 2 227-233 doi: 10.1016/j.tvjl.2006.12.006
Couroucé-Malblanc A, Fortier G, Pronost S, Siliart B, Brachet G.This study was designed to compare the efficacy of oral prednisolone and intramuscular (IM) dexamethasone in heaves-affected horses with environmental control. A total of 16 horses, aged 8-20years, with heaves were included in the study. Complete examinations were performed on Day 0 (before treatment), Day 13 (after treatment) and Day 30. Clinical variables, arterial blood gases, mucus scoring and carina evaluation (during endoscopy), and bronchoalveolar lavage (BAL) cytological analysis were all assessed. The horses were randomly assigned to receive either oral prednisolone (1mg/kg) or IM dex...
Cloning of equine prostaglandin dehydrogenase and its gonadotropin-dependent regulation in theca and mural granulosa cells of equine preovulatory follicles during the ovulatory process.
Reproduction (Cambridge, England)    February 20, 2007   Volume 133, Issue 2 455-466 doi: 10.1530/REP-06-0210
Sayasith K, Bouchard N, Doré M, Sirois J.The mammalian ovulatory process is accompanied by a gonadotropin-dependent increase in follicular levels of prostaglandin E2 (PGE2) and PGF2alpha, which are metabolized by 15-hydroxy prostaglandin dehydrogenase (PGDH). Little is known about ovarian PGDH regulation in non-primate species. The objectives of this study were to characterize the structure of equine PGDH and its regulation in follicles during human chorionic gonadotropin (hCG)-induced ovulation. The full-length equine PGDH was obtained by RT-PCR, 5'- and 3'-rapid amplification of cDNA ends (RACE). Its open reading frame encodes a 26...
Nuclear scintigraphy: uses and limitations.
Veterinary journal (London, England : 1997)    December 15, 2006   Volume 173, Issue 1 12-13 doi: 10.1016/j.tvjl.2006.01.001
Dyson S.No abstract available
Equine cloning.
The Veterinary clinics of North America. Equine practice    November 30, 2006   Volume 22, Issue 3 857-866 doi: 10.1016/j.cveq.2006.07.004
Hinrichs K.Equine cloning is now in use as a clinical technique. It is available commercially, and its efficiency seems to be increasing. The foals produced by cloning may differ in some phenotypic and behavioral traits from the original animal but should produce offspring that reflect those that the original donor animal would have produced. This is especially true in the case of male animals, where the mitochondrial DNA is not passed to the progeny. Results of pregnancies due in 2006 should add significantly to our understanding of the factors affecting production of viable cloned foals and of the simi...
Clinical trials of efficacy of praziquantel horse paste 9% against tapeworms and its safety in horses.
Veterinary parasitology    November 13, 2006   Volume 144, Issue 3-4 366-370 doi: 10.1016/j.vetpar.2006.09.038
Slocombe JO, Heine J, Barutzki D, Slacek B.The aim of this study with horses and a few ponies naturally infected with tapeworms was to confirm in clinical trials the efficacy and safety of a praziquantel horse paste 9%. The field trials were conducted in 1997 and 1998 in Canada, France, Germany and New Zealand. A secondary aim of the study in Canada was to determine if a 24h post-treatment fecal sample provides the best estimate of the prevalence of tapeworms in horses when using a fecal examination technique. Fecal samples were taken from each of 1062 animals at least three times pre-treatment (PRT). In Canada, fecal samples were exam...
Magnetic resonance imaging study in horses.
The Veterinary record    November 8, 2006   Volume 159, Issue 19 643 doi: 10.1136/vr.159.19.643-a
Smith M, Murray R, Dyson S, Mair T, Boswell J.No abstract available
Treatment of squamous cell carcinoma in a horse.
The Veterinary record    October 3, 2006   Volume 159, Issue 14 462-463 doi: 10.1136/vr.159.14.462-c
Ellis DR.No abstract available
Molecular cross-sectional survey of gastric habronemosis in horses.
Veterinary parasitology    June 23, 2006   Volume 141, Issue 3-4 285-290 doi: 10.1016/j.vetpar.2006.05.021
Traversa D, Iorio R, Capelli G, Paoletti B, Bartolini R, Otranto D, Giangaspero A.Gastric habronemosis of horses caused by Habronema microstoma and Habronema muscae (Nematoda, Spirurida) is characterized by catarrhal gastritis, diarrhoea, progressive weight loss and ulcers. Despite its importance in the equine industry and in clinical practice, knowledge of the epidemiology of this infection is still incomplete as diagnosis in live animals is challenging. A two-step semi-nested PCR assay using ribosomal DNA (rDNA) markers has recently been used for the molecular diagnosis in vivo of gastric habronemosis based on the detection of H. microstoma and/or H. muscae DNA in equine ...
Nuclear transfer saddles up.
Nature biotechnology    June 2, 2006   Volume 24, Issue 6 605-607 doi: 10.1038/nbt0606-605
Church SL.No abstract available
Ultrasonographic detection of a wooden foreign body in a horse.
The Veterinary record    May 30, 2006   Volume 158, Issue 21 739-740 doi: 10.1136/vr.158.21.739
Rademacher N, Fürst A, Kaser-Hotz B.No abstract available
Perinatal asphyxia syndrome in a quarter horse foal.
The Veterinary clinics of North America. Equine practice    April 22, 2006   Volume 22, Issue 1 193-208 doi: 10.1016/j.cveq.2005.12.007
Katz L.No abstract available
Equine disease surveillance, October to December 2005.
The Veterinary record    March 28, 2006   Volume 158, Issue 12 390-392 doi: 10.1136/vr.158.12.390
No abstract available
Unintended lessons from the veterinarian.
Annals of emergency medicine    March 27, 2006   Volume 48, Issue 6 757-758 doi: 10.1016/j.annemergmed.2006.02.007
Braude D.No abstract available
Endothelin receptor alterations in equine airway hyperreactivity. Venugopal CS, Polikepahad S, Holmes EP, Heuvel JV, Leas TL, Moore RM.The purpose of this study was to evaluate the role of endothelin-1 (ET-1) and its receptors in the airway hyperreactivity of horses with obstructive pulmonary disease associated with summer pasture (SPAOPD). The right diaphragmatic lobe of the lung of 8 clinically healthy (unaffected) and 8 SPAOPD-affected horses was collected immediately after euthanasia. Bronchial rings (4 mm wide) were prepared and mounted in organ baths and attached to force transducers interfaced with a polygraph. Four rings were used to study each ET-1 receptor; 1 ring served as the control, and the other 3 were incubate...
The temporomandibular joint: component of clinical complexity.
Equine veterinary journal    March 16, 2006   Volume 38, Issue 2 102-104 doi: 10.2746/042516406776563323
Ramzan PH.No abstract available
Theriogenology question of the month. What are the 3 management options for a mare with twin fetuses at this stage of gestation?
Journal of the American Veterinary Medical Association    January 24, 2006   Volume 228, Issue 2 207-209 doi: 10.2460/javma.228.2.207
Gray GA, Dascanio JJ, Kolster KA.No abstract available
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